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Hori Yuichiro Last modified date：2024.06.03

Professor / Organic Chemistry and Biochemistry
Department of Chemistry
Faculty of Sciences


Graduate School
Department of Chemistry
Graduate School of Sciences
Undergraduate School
Department of Chemistry
School of Sciences


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Homepage
https://kyushu-u.elsevierpure.com/en/persons/yuichiro-hori
　Reseacher Profiling Tool　Kyushu University Pure
http://chem.kyushu-univ.jp/horilab/en/index.html
Homepage for Laboratory of Dynamic Chemical Life Science .
Phone
092-802-4161
Academic Degree
Ph.D.
Country of degree conferring institution (Overseas)
No
Field of Specialization
Chemical biology, Fluorescence imaging, Protein chemistry
ORCID(Open Researcher and Contributor ID)
0000-0002-2905-5502
Total Priod of education and research career in the foreign country
02years04months
Outline Activities
I am developing chemical biology techniques to label and visualize proteins with synthetic fluorescent molecules by devising and applying chemical principles. In living cells, countless biomolecules exist, dynamically changing their localization and controlling cellular events by performing the biomolecular functions in a subcellular region where they are needed. Visualization of the movement of these biomolecules provides important information to elucidate the physiological functions they control. Coworkers and I have developed original technology for fluorescent labeling of proteins to reveal how proteins move in living cells and regulate biological phenomena. Furthermore, I aim to elucidate biological phenomena regulated by nucleic acids, glycans, and extracellular vesicles in addition to proteins, and to control functions of biomolecules at will by making full use of our protein labeling technology.
Research
Research Interests
  • Dynamic chemical life science
    keyword : Chemical biology, fluorescence imaging, fluorescence labeling
    2022.04.
Academic Activities
Reports
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Papers
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1. Kenji Torii, Sam Benson, Yuichiro Hori, Marc Vendrell, Kazuya Kikuchi , No-wash fluorogenic labeling of proteins for reversible photoswitching in live cells, Chemical Science, 10.1039/d3sc04953a , 15, 4, 1393-1401, 2023.12.
2. Miyako Nishiura, Yuichiro Hori, Maho Umeno, Kazuya Kikuchi, Visualization of multiple localizations of GLUT4 by fluorescent probes of PYP-tag with designed unnatural warhead, Chemical Science, 10.1039/d3sc00724c, 2023.05, Fluorescent probes with a designed unnatural warhead for binding to PYP-tag enabled intracellular/cell-surface selective protein labeling. This unique imaging tool was successfully applied to reveal multiple subcellular localizations of GLUT4..
Membership in Academic Society
  • THE CHEMICAL SOCIETY OF JAPAN
  • THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
  • JAPANESE SOCIETY FOR CHEMICAL BIOLOGY


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