TOCAN VLAD
Organization
Kyushu University Hospital Pediatrics Assistant Professor
Title
Assistant Professor
Profile
Areas of expertise: pediatric endocrinology, inherited metabolic disorders, genetic disorders
Homepage
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https://pediatr.kyushu-u.ac.jp/
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University
External link
ORCID
Degree
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Master of Human and Environmental Studies (Kyoto University)
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Ph.D. in Medicine (Kyushu University)
Research Interests・Research Keywords
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Research theme：Inherited metabolic disorders
Keyword：Inherited metabolic disorders
Research period： 2015.4
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Research theme：Pediatric endocrine diseases
Keyword：Pediatric endocrinology
Research period： 2015.4
Papers
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Hepatocyte polarity establishment and apical lumen formation are organized by Par3, Cdc42, and aPKC in conjunction with Lgl Reviewed International journal
@Vlad Tocan, @Junya Hayase, @Sachiko Kamakura, @Akira Kohda, @Shouichi Ohga, @Motoyuki Kohjima, @Hideki Sumimoto
JOURNAL OF BIOLOGICAL CHEMISTRY 297 ( 6 ) 2021.12
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Reappraising newborn screening for cobalamin C disorder Reviewed International journal
@Vlad Tocan, @Kazuhiro Ohkubo, @Kanako Higashi, @Naoko Toda, @Kanako Kojima-Ishii, @Kei Nishiyama, @Masataka Ishimura, @Hidetoshi Takada, @Osamu Sakamoto, @Fusako Sasaki, @Kazuko Yoshimura, @Shinichi Hirose, @Shouichi Ohga
PEDIATRICS AND NEONATOLOGY 59 ( 4 ) 415 - 417 2018.8
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Long-lasting pain and somatosensory disturbances in children with myelin oligodendrocyte glycoprotein antibody-associated disease: A single-institute study Reviewed International journal
@Yuko Ichimiya, @Pin Fee Chong, @Yuri Sonoda, @Vlad Tocan, @Mitsuru Watanabe, @Hiroyuki Torisu, @Ryutaro Kira, @Toshiyuki Takahashi, @Jun-Ichi Kira, @Noriko Isobe, @Yasunari Sakai, @Shouichi Ohga
European Journal of Pediatrics 2023.4
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The earliest enzyme replacement for infantile-onset Pompe disease in Japan Invited Reviewed International journal
PEDIATRICS INTERNATIONAL 64 ( 1 ) 2022.1
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Physical growth and neurodevelopment during the first year of life: a cohort study of the Japan Environment and Children's Study Reviewed International journal
BMC PEDIATRICS 21 ( 1 ) 2021.8
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Malignant Transformation of Phosphaturic Mesenchymal Tumor: A Case Report and Literature Review. Invited Reviewed International journal
@Oyama N, @Kojima-Ishii K, @Toda N, @Matsuo T, @Tocan V, @Ohkubo K, @Oba U, @Koga Y, @Setsu N, @Yamada Y, @Kohashi K, @Nakashima Y, @Oda Y, @Ihara K, @Ohga S.
Clin Pediatr Endocrinol. 29 ( 2 ) 69 - 75 2020.4
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The expanding phenotype of hypokalemic periodic paralysis in a Japanese family with p.Val876Glu mutation in CACNA1S Reviewed International journal
@Kurokawa M, @Torio M, @Ohkubo K, @Tocan V, @Ohyama N, @Toda N, @Ishii K, @Nishiyama K, @Mushimoto Y, @Sakamoto R, @Nakaza M, @Horie R, @Kubota T, @Takahashi MP, @Sakai Y, @Nomura M, @Ohga S.
MOLECULAR GENETICS & GENOMIC MEDICINE 8 ( 4 ) 2020.4
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Metabolic and immunological assessment of small-for-gestational-age children during one-year treatment with growth hormone: the clinical impact of apolipoproteins Reviewed International journal
@Kojima-Ishii K, @Toda N, @Okubo K, @Tocan V, @Ohyama N, @Makimura M, @Matsuo T, @Ochiai M, @Ohga S, @Ihara K
Endocrine Journal 65 ( 4 ) 449 - 459 2018.4
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Severe Hemolytic Anemia Following Intravenous Immunoglobulin in an Infant With Kawasaki Disease Invited Reviewed International journal
@Vlad Tocan, @Akari Inaba, @Tamami Kurano, @Motoshi Sonoda, @Keiji Soebijanto, @Hideki Nakayama
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY 39 ( 2 ) E100 - E102 2017.3
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Is Metastatic Rhabdomyosarcoma an Indication for Cardioverter Defibrillator Implantation? Reviewed International journal
@Vlad Tocan, @Yuhki Koga, @Hiroaki Ono, @Kentaro Nakashima, @Eiko Terashi, @Eiji Morihana, @Kenichiro Yamamura, @Takafumi Sakamoto, @Hidetoshi Takada
Pediatric Blood and Cancer 63 ( 8 ) 1501 - 1502 2016.8
Presentations
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Diagnosing uncertainty: suspected VLCAD deficiency in an infant with two ACADVL variants of uncertain significance
@Vlad Tocan, @Taro Shimamoto, @Yuichi Mushimoto, @Nozomi Abe, @Kanako Kojima-Ishii, @Shouichi Ohga
2022.12
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Suspected VLCAD deficiency in an infant with two ACADVL variants of uncertain significance
2022.11
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シャペロン療法の早期導入が神経症状に有効であったゴーシェ病2型の1歳児例
@トカン ヴラッド、@中尾泰介、@園田有里、@虫本雄一、@戸田尚子、@石井加奈子、@澤田 貴彰、@中村公俊、@大賀正一
第62回日本先天代謝異常学会学術集会 2021.11
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Central precocious puberty in a boy with pseudohypoparathyroidism type 1B
@Vlad Tocan, @Yuichi Mushimoto, @Kanako Kojima-Ishii, @Naoko Toda, @Shouichi Ohga
2021.10
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拡張型心筋症に対する補助人工心臓留置後の代謝発作から診断されたプロピオン酸血症の18歳男性
@島本太郎、@石井加奈子、@トカン ヴラッド、@安部希、@虫本雄一、@鳥尾倫子、@藤野剛雄、@大賀正一
第63回日本先天代謝異常学会学術集会 2023.11
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乳児期から高血圧を呈し、10歳時にKCNJ5変異が同定された家族性原発性アルドステロン症Ⅲ型の女児例
@牟田龍史、@石井加奈子、@安部希、@トカン ヴラッド、@虫本雄一、@長友雄作、@大野拓郎、@内田登、@長谷川奉延、@大賀正一
第55回日本小児内分泌学会学術集会 2022.11
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心不全から診断されたプロピオン酸血症の18歳男性
@安部希、@石井加奈子、@トカン ヴラッド、@虫本雄一
第７回女性医師による九州先天代謝異常ネットワークミーティング 2022.10
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心不全から診断されたプロピオン酸血症の18歳男性
@島本太郎、@石井加奈子、@トカン ヴラッド、@安部希、@虫本雄一、@鳥尾倫子、@藤野剛雄、@大賀正一
第518回日本小児科学会福岡地方会 2022.9
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生後9か月時に胃腸炎関連痙攣を契機に診断された原発性アルドステロン症女児例
@牟田龍史、@石井加奈子、@戸田尚子、@トカン ヴラッド、@虫本雄一
第5回日本小児内分泌学会九州・沖縄地方会 2022.2
Professional Memberships
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Japanese Society for Clinical Nutrition and Metabolism
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Japanese Society for Inherited Metabolic Diseases
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The Japan Society of Human Genetics
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The Japanese Society for Pediatric Endocrinology
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The Japan Endocrine Society
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Japan Pediatric Society
Research Projects
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ライソゾーム病患者における免疫異常の解析
2022.4 - 2027.3
Authorship：Principal investigator
Educational Activities
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I lecture for the second-year students of the Departments of Medicine and Biomedical Studies and supervise students during their basic research (third year), bedside practice (fourth and fifth year), and clinical clerkship (sixth year) programs.
Class subject
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遺伝学
2023.10 - 2024.3 Second semester
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臨床医学実習
2023.4 - 2024.3 Full year
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臨床医学基礎実習
2023.4 - 2023.9 First semester
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クリニカルクラークシップ
2023.4 - 2023.9 First semester
Specialized clinical area
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Biology / Medicine, Dentistry and Pharmacy / Internal Medicine / Pediatrics
Clinician qualification
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Specialist
Japan Pediatric Society
Year of medical license acquisition
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2012