https://kyushu-u.elsevierpure.com/en/persons/rie-sonoi
　Reseacher Profiling Tool　Kyushu University Pure

092-802-2805

No

Biochemical engineering

https://orcid.org/0000-0002-8597-8942

00years00months

Establishment of non-invasive and quantitative evaluation methods based on cell characteristics and behaviors

Research Interests

• １．Study on quantitative evaluation and regulation of the maturation through the migratory behaviors of human retinal pigment epithelial cells in confluent state (2011-2017).
  ２．Study on the development of process and quality control technology for inducing differentiation of human iPS cells into retinal pigment epithelial cells for use in the transplantation (2014-2015).
  ３．Study on the development of quantitative and non-invasive evaluation methods to understand drug toxicity in HepaRG aggregates using Optical Coherence Tomography (OCT) (2018-2021).
  ４．Study on establishment of quantitative and non-invasive evaluation methods to understand drug toxicity based on the change in the bile canaliculi behaviors of Hepatocytes (2018-2022).
  keyword : confluent state, epithelial cells, non-invasive evaluation, image analysis, regenerative medicine, drug discovery
  2023.01.
• A novel strategy to facilitate uniform epithelial cell maturation using liquid–liquid interfaces
  keyword : liquid-liquid interfaces，epithelial cell, uniform maturation, tight junction, cell behavior
  2023.04～2025.03.

Academic Activities
Membership in Academic Society

• The society for biotechnology
• The japanese society for regenerative medicine
• Parenteral Drug Association
• The Japanese Society for Biomaterials