https://kyushu-u.elsevierpure.com/en/persons/eikichi-ihara
　Reseacher Profiling Tool　Kyushu University Pure

http://www.intmed3.med.kyushu-u.ac.jp/english/
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, .

MD, PhD

No

Gastroenterology, Endoscopy, Gastrointestinal motility disorder, Disorders of Gut-Brain Interaction

0000-0002-7070-6610

04years00months

Outline of research:
Coordinated regulation of gastrointestinal (GI) motility contributes to general health and wellness when functioning normally but is also associated with morbidity and mortality when dysfunctional. Alterations in GI motility with resultant changes in transit can contribute to abdominal pain, intestinal cramping, diarrhea, constipation and urgency to defecate.The GI smooth muscle itself plays an important role in gastrointestinal (GI) motility. In overt inflammatory conditions of the bowel, such as infectious colitis and inflammatory bowel disease (IBD), there have been longstanding observations of altered motility and impaired function of the GI smooth muscle. While the inflammatory mediators are known to affect GI smooth muscle and impaired gastrointestinal motility, it still remains to be investigated how the inflammatory mediators affects GI smooth muscle. The research goals are to those mechanisms which possibly lead to generation of novel therapeutics for patients with GI motility disorders.
Education:
I give lectures on gastroenterology and metabolic gastroenterology to medical students in kyushu university. I also instruct, supervise and evaluate their clinical trainings. Alternatively, I teach gastroenterological endoscopy and radiology to gastroenterology trainees.

Research Interests

• The research about chronic constipation
  keyword : Constipation
  2023.04～2027.03.
• Elucidation of underlying pathogenesis of esophageal achalasia
  keyword : esophageal achalasia
  2023.04～2025.03.
• Etiology and pathogenesis of esophageal motility disorders and their novel treatments
  keyword : Esophageal motility disorder, high-resolution manometry
  2016.04～2025.03.
• The underlying mechanisms of regulation of lower esophageal sphincter tone.
  keyword : Lower esophageal sphincter、Mechanism of smooth muscle contraction、Myogenic tone regulation、Rho kinase
  2016.04～2025.03.
• To elucidate the pathogenesis of Gastroesophageal reflux disease
  keyword : High resolution manometry、Esophageal impedance-pH monitoring、Gastroesophageal reflux disease、Esophageal motility disorders
  2016.04～2025.03.
• The underlying mechanisms by which intestinal inflammation associated with various gastrointestinal (GI) disorders impairs contractile function of intestinal smooth muscle and GI motility.
  keyword : altered GI motility, intestinal smooth muscle, intestinal inflammation
  2016.04～2021.03.

Academic Activities