Nanotechnology/Materials / Chemical biology

Mode of molecular interaction of triterpenoid saponin ginsenoside Rh2 with membrane lipids in liquid-disordered phases

Darcy Garza-Miyazato, Shinya Hanashima, Yuichi Umegawa, Michio Murata, Masanao Kinoshita, Nobuaki Matsumori, Peter Greimel

Biochimica et Biophysica Acta (BBA) - Biomembranes   1866 ( 7 )   184366 - 184366   2024.10   （ ISSN:0005-2736 eISSN:1879-2642 ）

Highly Sensitive Two-dimensional Profiling of N-linked Glycans by Hydrophilic Interaction Liquid Chromatography and Dual Stacking Capillary Gel Electrophoresis

Takaya Miki, Sachio Yamamoto, Chenchen Liu, Kohei Torikai, Mitsuhiro Kinoshita, Nobuaki Matsumori, Takayuki Kawai

Analytica Chimica Acta   1320   342990 - 342990   2024.9   （ ISSN:0003-2670 eISSN:1873-4324 ）

Identification of lipid-specific proteins with high-density lipid-immobilized beads

Masayuki Morito, Hiroki Yasuda, Takaaki Matsufuji, Masanao Kinoshita, Nobuaki Matsumori

The Analyst   149 ( 14 )   3747 - 3755   2024.7   （ ISSN:0003-2654 eISSN:1364-5528 ）

Gold nanoparticle-powered screening of membrane protein-specific lipids from complex lipid mixtures Reviewed International journal

Supakorn Wangamnuayporn, Masanao Kinoshita, Takayuki Kawai, Nobuaki Matsumori

Analytical Biochemistry   687   115447   2024.4   （ ISSN:0003-2697 eISSN:1096-0309 ）

Truncated derivatives of amphidinol 3 reveal the functional role of polyol chain in sterol-recognition and pore formation Reviewed International journal

Nobuaki Matsumori, Manami Hieda, Masayuki Morito, Yuma Wakamiya, Tohru Oishi

Bioorganic & Medicinal Chemistry Letters   98   129594   2024.1   （ ISSN:0960-894X eISSN:1464-3405 ）

Cardiolipin binding enhances KcsA channel gating via both its specific and dianion-monoanion interchangeable sites Reviewed International journal

Masayuki Iwamoto, Masayuki Morito, Shigetoshi Oiki, Yudai Nishitani, Daisuke Yamamoto, Nobuaki Matsumori

iScience   26 ( 12 )   108471 - 108471   2023.12   （ ISSN:2589-0042 eISSN:2589-0042 ）

Variational autoencoder-based chemical latent space for large molecular structures with 3D complexity Reviewed International journal

Toshiki Ochiai, Tensei Inukai, Manato Akiyama, Kairi Furui, Masahito Ohue, Nobuaki Matsumori, Shinsuke Inuki, Motonari Uesugi, Toshiaki Sunazuka, Kazuya Kikuchi, Hideaki Kakeya, Yasubumi Sakakibara

Communications Chemistry   6 ( 1 )   249   2023.11   （ ISSN:2399-3669 ）

Impact of sphingomyelin acyl chain heterogeneity upon properties of raft-like membranes. Reviewed International journal

Kana Hirano, Masanao Kinoshita, Nobuaki Matsumori

Biochimica et biophysica acta. Biomembranes   1864 ( 12 )   184036 - 184036   2022.12   （ ISSN:0005-2736 eISSN:1879-2642 ）

Formation of a tight complex between amphidinol 3 and sterols in lipid bilayers revealed by short-range energy transfer Reviewed International journal

Manami Hieda, Koya Tsujimura, Masanao Kinoshita, Nobuaki Matsumori

Bulletin of the Chemical Society of Japan   95 ( 12 )   1753 - 1759   2022.11   （ ISSN:0009-2673 eISSN:1348-0634 ）

Behavior of Triterpenoid Saponin Ginsenoside Rh2 in Ordered and Disordered Phases in Model Membranes Consisting of Sphingomyelin, Phosphatidylcholine, and Cholesterol Reviewed International journal

Darcy Lacanilao Garza, Shinya Hanashima, Yuichi Umegawa, Michio Murata, Masanao Kinoshita, Nobuaki Matsumori, Peter Greimel

Langmuir   38 ( 34 )   10478 - 10491   2022.8   （ ISSN:0743-7463 eISSN:1520-5827 ）

Inimitable Impacts of Ceramides on Lipid Rafts Formed in Artificial and Natural Cell Membranes Reviewed International journal

Masanao Kinoshita, Nobuaki Matsumori

Membranes   12 ( 8 )   727 - 727   2022.7   （ ISSN:2077-0375 eISSN:2077-0375 ）

Molecular substructure of the liquid-ordered phase formed by sphingomyelin and cholesterol: sphingomyelin clusters forming nano-subdomains are a characteristic feature Reviewed International journal

Michio Murata, Nobuaki Matsumori, Masanao Kinoshita, Erwin London

Biophysical Reviews   14 ( 3 )   655 - 678   2022.6   （ ISSN:1867-2450 eISSN:1867-2469 ）

Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study. Reviewed International journal

Yuichi Umegawa, Tomoya Yamamoto, Mayank Dixit, Kosuke Funahashi, Sangjae Seo, Yasuo Nakagawa, Taiga Suzuki, Shigeru Matsuoka, Hiroshi Tsuchikawa, Shinya Hanashima, Tohru Oishi, Nobuaki Matsumori, Wataru Shinoda, Michio Murata

Science advances   8 ( 24 )   eabo2658   2022.6   （ ISSN:2375-2548 ）

Binding of cardiolipin to the KcsA channel at the membrane outer leaflet allosterically opens the inner gate

Masataka Inada, Masayuki Iwamoto, Norio Yoshida, Shigetoshi Oiki, Nobuaki Matsumori

2022.2

脂質ラフトを標的とする局所麻酔薬の作用機序

木下 祥尚, 松森 信明

Medical Science Digest   48   50 - 51   2022

Recent advances in microscale separation techniques for lipidome analysis. Invited Reviewed International journal

Takayuki Kawai, Nobuaki Matsumori, Koji Otsuka

The Analyst   146 ( 24 )   7418 - 7430   2021.12

Preparation of Nitrogen Analogues of Ceramide and Studies of Their Aggregation in Sphingomyelin Bilayers. International journal

Hiroki Yasuda, Kohei Torikai, Masanao Kinoshita, Md Abdullah Al Sazzad, Koya Tsujimura, J Peter Slotte, Nobuaki Matsumori

Langmuir : the ACS journal of surfaces and colloids   37 ( 42 )   12438 - 12446   2021.10

Amphidinol 3 preferentially binds to cholesterol in disordered domains and disrupts membrane phase separation. International journal

Manami Hieda, Akira Sorada, Masanao Kinoshita, Nobuaki Matsumori

Biochemistry and biophysics reports   26   100941 - 100941   2021.7

【再訪:麻酔メカニズム】脂質ラフトと麻酔メカニズム Invited Reviewed

松森 信明

麻酔   70 ( 7 )   724 - 731   2021.7

Metal Complex Lipids for Fluid-Fluid Phase Separation in Coassembled Phospholipid Membranes. International journal

Ryo Ohtani, Yuka Anegawa, Hikaru Watanabe, Yutaro Tajima, Masanao Kinoshita, Nobuaki Matsumori, Kenichi Kawano, Saeko Yanaka, Koichi Kato, Masaaki Nakamura, Masaaki Ohba, Shinya Hayami

Angewandte Chemie (International ed. in English)   60 ( 24 )   13603 - 13608   2021.6

Low-flux scanning electron diffraction reveals substructures inside the ordered membrane domain. International journal

Masanao Kinoshita, Shimpei Yamaguchi, Nobuaki Matsumori

Scientific reports   10 ( 1 )   22188 - 22188   2020.12

Pseudo-Membrane Jackets Two-Dimensional Coordination Polymers Achieving Visible Phase Separation in Cell Membrane Reviewed

Ryo Ohtani, Kenichi Kawano, Masanao Kinoshita, Saeko Yanaka, Hikaru Watanabe, Kenji Hirai, Shiroh Futaki, Nobuaki Matsumori, Hiroshi Uji-i, Masaaki Ohba, Koichi Kato, Shinya Hayami

Angewandte Chemie - International Edition   59 ( 41 )   17931 - 17937   2020.10

局所麻酔の新たなメカニズム

松森 信明

日本ペインクリニック学会誌   27 ( 3 )   IL1 - IL1   2020.10

Assembly formation of minor dihydrosphingomyelin in sphingomyelin-rich ordered membrane domains. International journal

Masanao Kinoshita, Takumi Kyo, Nobuaki Matsumori

Scientific reports   10 ( 1 )   11794 - 11794   2020.7

Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane Reviewed International journal

Shinichi Nishimura, Nobuaki Matsumori

Natural Product Reports   37 ( 5 )   677 - 702   2020.5

Biophysics at Kyushu University. Reviewed International journal

Ryo Akiyama, Masahiko Annaka, Daisuke Kohda, Hiroyuki Kubota, Yusuke Maeda, Nobuaki Matsumori, Daisuke Mizuno, Norio Yoshida

Biophysical reviews   12 ( 2 )   245 - 247   2020.4

Total Synthesis of Amphidinol 3: A General Strategy for Synthesizing Amphidinol Analogues and Structure-Activity Relationship Study. International journal

Yuma Wakamiya, Makoto Ebine, Nobuaki Matsumori, Tohru Oishi

Journal of the American Chemical Society   142 ( 7 )   3472 - 3478   2020.2

The influence of ceramide and its dihydro analog on the physico-chemical properties of sphingomyelin bilayers Reviewed

Masanao Kinoshita, Kaoru Tanaka, Nobuaki Matsumori

Chemistry and Physics of Lipids   226   2020.1

Archaeal Glycolipid S-TGA-1 Is Crucial for Trimer Formation and Photocycle Activity of Bacteriorhodopsin Reviewed International journal

Masataka Inada, Masanao Kinoshita, Nobuaki Matsumori

ACS Chemical Biology   15 ( 1 )   197 - 204   2020.1

Defining raft domains in the plasma membrane Reviewed

Akihiro Kusumi, Takahiro K. Fujiwara, Taka A. Tsunoyama, Rinshi S. Kasai, An An Liu, Koichiro M. Hirosawa, Masanao Kinoshita, Nobuaki Matsumori, Naoko Komura, Hiromune Ando, Kenichi G.N. Suzuki

Traffic   21 ( 1 )   106 - 137   2020.1

The Amphotericin B–Ergosterol Complex Spans a Lipid Bilayer as a Single-Length Assembly Reviewed

58 ( 51 )   5188 - 5196   2019.12

天然物のNMR研究―立体化学決定および溶液中と膜中における配座解析

松森信明

10   76‐81 (WEB ONLY)   2019.11

Mechanism of local anesthetic-induced disruption of raft-like ordered membrane domains Reviewed

Masanao Kinoshita, Takeshi Chitose, Nobuaki Matsumori

Biochimica et Biophysica Acta - General Subjects   1863 ( 9 )   1381 - 1389   2019.9

Cholesterol-Induced Conformational Change in the Sphingomyelin Headgroup Reviewed

Shinya Hanashima, Kazuhiro Murakami, Michihiro Yura, Yo Yano, Yuichi Umegawa, Hiroshi Tsuchikawa, Nobuaki Matsumori, Sangjae Seo, Wataru Shinoda, Michio Murata

Biophysical Journal   117 ( 2 )   307 - 318   2019.7

A concise method for quantitative analysis of interactions between lipids and membrane proteins. Reviewed International journal

Masataka Inada, Masanao Kinoshita, Ayumi Sumino, Shigetoshi Oiki, Nobuaki Matsumori

Analytica chimica acta   1059   103 - 112   2019.6

The Perpendicular Orientation of Amphotericin B Methyl Ester in Hydrated Lipid Bilayers Supports the Barrel-Stave Model Reviewed

Tomoya Yamamoto, Yuichi Umegawa, Masaki Yamagami, Taiga Suzuki, Hiroshi Tsuchikawa, Shinya Hanashima, Nobuaki Matsumori, Michio Murata

Biochemistry   58 ( 17 )   2282 - 2291   2019.4

Preparation and Membrane Distribution of Fluorescent Derivatives of Ceramide Reviewed

Takaaki Matsufuji, Masanao Kinoshita, Nobuaki Matsumori

Langmuir   2019.1

On the Importance of the C(1)-OH and C(3)-OH Functional Groups of the Long-Chain Base of Ceramide for Interlipid Interaction and Lateral Segregation into Ceramide-Rich Domains Reviewed

Langmuir   34 ( 51 )   15864 - 15870   2018.12

蛍光修飾したスフィンゴミエリン誘導体の脂質ラフト観察への応用

木下 祥尚, 松森 信明

生物物理   58 ( 6 )   321 - 323   2018.11

Sphingomyelin Stereoisomers Reveal That Homophilic Interactions Cause Nanodomain Formation Reviewed

Yo Yano, Shinya Hanashima, Tomokazu Yasuda, Hiroshi Tsuchikawa, Nobuaki Matsumori, Masanao Kinoshita, Md Abdullah Al Sazzad, J. Peter Slotte, Michio Murata

Biophysical Journal   115 ( 8 )   1530 - 1540   2018.10

Evidence of lipid rafts based on the partition and dynamic behavior of sphingomyelins Reviewed

Masanao Kinoshita, Kenichi G.N. Suzuki, Michio Murata, Nobuaki Matsumori

Chemistry and Physics of Lipids   215   84 - 95   2018.9

生体膜を標的にする天然有機化合物 天然物による厳密な脂質認識とそれに基づく表現型

西村 慎一, 掛谷 秀昭, 松森 信明

化学と生物   56 ( 10 )   678 - 684   2018.9

Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol. Reviewed

Cornelio K, Espiritu RA, Hanashima S, Todokoro Y, Malabed R, Kinoshita M, Matsumori N, Murata M, Nishimura S, Kakeya H, Yoshida M, Matsunaga S

Biochimica et biophysica acta. Biomembranes   1861 ( 1 )   228 - 235   2018.7

Synthesis and Stereochemical Revision of the C31-C67 Fragment of Amphidinol 3 Reviewed

Yuma Wakamiya, Makoto Ebine, Mariko Murayama, Hiroyuki Omizu, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Angewandte Chemie   130 ( 21 )   6168   2018.5

Synthesis and Stereochemical Revision of the C31–C67 Fragment of Amphidinol 3 Reviewed

57 ( 21 )   6060 - 6064   2018.5

Synthesis and complete structure determination of a sperm-activating and -attracting factor isolated from the ascidian ascidia sydneiensis Reviewed

Tomohiro Watanabe, Hajime Shibata, Makoto Ebine, Hiroshi Tsuchikawa, Nobuaki Matsumori, Michio Murata, Manabu Yoshida, Masaaki Morisawa, Shu Lin, Kosei Yamauchi, Ken Sakai, Tohru Oishi

Journal of Natural Products   81 ( 4 )   985 - 997   2018.4

Dynamic membrane interactions of antibacterial and antifungal biomolecules, and amyloid peptides, revealed by solid-state NMR spectroscopy Reviewed

Akira Naito, Nobuaki Matsumori, Ayyalusamy Ramamoorthy

Biochimica et Biophysica Acta - General Subjects   1862 ( 2 )   307 - 323   2018.2

Preparation and Membrane Properties of Oxidized Ceramide Derivatives Reviewed

Langmuir   34 ( 1 )   465 - 471   2018.1

Recent Solid-State NMR Studies of Hydrated Lipid Membranes Reviewed

Yuichi Umegawa, Nobuaki Matsumori, Michio Murata

Annual Reports on NMR Spectroscopy   2018.1

Channel Formation and Membrane Deformation via Sterol-Aided Polymorphism of Amphidinol Reviewed

Masayuki Iwamoto, Ayumi Sumino, Eri Shimada, Masanao Kinoshita, Nobuaki Matsumori, Shigetoshi Oiki

Scientific Reports   7 ( 1 )   2017.12

The impact of metal complex lipids on viscosity and curvature of hybrid liposomes Reviewed International journal

Ryo Ohtani, Tsukasa Tokita, Tomohisa Takaya, Koichi Iwata, Masanao Kinoshita, Nobuaki Matsumori, Masaaki Nakamura, Leonard F. Lindoy, Shinya Hayami

Chemical Communications   53 ( 99 )   13249 - 13252   2017.12

Emphatic visualization of sphingomyelin-rich domains by inter-lipid FRET imaging using fluorescent sphingomyelins Reviewed

Masanao Kinoshita, Hikaru Ano, Michio Murata, Kenta Shigetomi, Junichi Ikenouchi, Nobuaki Matsumori

Scientific Reports   7 ( 1 )   2017.12

NMR studies on natural product-stereochemical determination and conformational analysis in solution and in membrane

Nobuaki Matsumori, Michio Murata

Experimental Approaches of NMR Spectroscopy Methodology and Application to Life Science and Materials Science   383 - 414   2017.11

Structures of the Largest Amphidinol Homologues from the Dinoflagellate Amphidinium carterae and Structure-Activity Relationships Reviewed

Masayuki Satake, Kimberly Cornelio, Shinya Hanashima, Raymond Malabed, Michio Murata, Nobuaki Matsumori, Huiping Zhang, Fumiaki Hayashi, Shoko Mori, Jong Souk Kim, Chang Hoon Kim, Jong Soo Lee

Journal of Natural Products   80 ( 11 )   2883 - 2888   2017.11

Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent Reviewed

Takanori Nakane, Shinya Hanashima, Mamoru Suzuki, Haruka Saiki, Taichi Hayashi, Keisuke Kakinouchi, Shigeru Sugiyama, Satoshi Kawatake, Shigeru Matsuoka, Nobuaki Matsumori, Eriko Nango, Jun Kobayashi, Tatsuro Shimamura, Kanako Kimura, Chihiro Mori, Naoki Kunishima, Michihiro Sugahara, Yoko Takakyu, Shigeyuki Inoue, Tetsuya Masuda, Toshiaki Hosaka, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Tsuyoshi Inoue, Osamu Nureki, So Iwata, Michio Murata, Eiichi Mizohata

Proceedings of the National Academy of Sciences of the United States of America   113 ( 46 )   13039 - 13044   2016.11

The Structure of the Bimolecular Complex between Amphotericin B and Ergosterol in Membranes Is Stabilized by Face-to-Face van der Waals Interaction with Their Rigid Cyclic Cores Reviewed

Yasuo Nakagawa, Yuichi Umegawa, Naohiro Matsushita, Tomoya Yamamoto, Hiroshi Tsuchikawa, Shinya Hanashima, Tohru Oishi, Nobuaki Matsumori, Michio Murata

Biochemistry   55 ( 24 )   3392 - 3402   2016.6

Marine sponge cyclic peptide theonellamide A disrupts lipid bilayer integrity without forming distinct membrane pores Reviewed

Rafael Atillo Espiritu, Kimberly Cornelio, Masanao Kinoshita, Nobuaki Matsumori, Michio Murata, Shinichi Nishimura, Hideaki Kakeya, Minoru Yoshida, Shigeki Matsunaga

Biochimica et Biophysica Acta - Biomembranes   1858 ( 6 )   1373 - 1379   2016.6

Lipid Interactions and Organization in Complex Bilayer Membranes Reviewed

Oskar Engberg, Tomokazu Yasuda, Victor Hautala, Nobuaki Matsumori, Thomas K.M. Nyholm, Michio Murata, J. Peter Slotte

Biophysical Journal   110 ( 7 )   1563 - 1573   2016.4

TmDOTA as versatile thermometer compound for solid-state NMR of hydrated lipid bilayer membranes Reviewed

Yuichi Umegawa, Yuya Tanaka, Nobuaki Matsumori, Michio Murata

Magnetic Resonance in Chemistry   54 ( 3 )   227 - 233   2016.3

Sterol-dependent membrane association of the marine sponge-derived bicyclic peptide Theonellamide A as examined by¹H NMR Reviewed

Kimberly Cornelio, Rafael Atillo Espiritu, Yasuto Todokoro, Shinya Hanashima, Masanao Kinoshita, Nobuaki Matsumori, Michio Murata, Shinichi Nishimura, Hideaki Kakeya, Minoru Yoshida, Shigeki Matsunaga

Bioorganic and Medicinal Chemistry   24 ( 21 )   5235 - 5242   2016.1

Formation of Gel-like Nanodomains in Cholesterol-Containing Sphingomyelin or Phosphatidylcholine Binary Membrane As Examined by Fluorescence Lifetimes and ²H NMR Spectra Reviewed

Langmuir   31 ( 51 )   13783 - 13792   2015.12

Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane Reviewed International journal

BIOORGANIC & MEDICINAL CHEMISTRY   23 ( 17 )   5782 - 5788   2015.9

Bioactive Structure of Membrane Lipids and Natural Products Elucidated by a Chemistry-Based Approach Reviewed

Michio Murata, Shigeru Sugiyama, Shigeru Matsuoka, Nobuaki Matsumori

Chemical Record   15 ( 4 )   675 - 690   2015.8

Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior Reviewed International journal

BIOORGANIC & MEDICINAL CHEMISTRY   23 ( 13 )   2989 - 2994   2015.7

Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior Reviewed International journal

BIOORGANIC & MEDICINAL CHEMISTRY   23 ( 13 )   2015.7

Stereoselective synthesis of the head group of archaeal phospholipid PGP-Me to investigate bacteriorhodopsin-lipid interactions Reviewed International journal

ORGANIC & BIOMOLECULAR CHEMISTRY   13 ( 41 )   10279 - 10284   2015.6

Orientation and Order of the Amide Group of Sphingomyelin in Bilayers Determined by Solid-State NMR Reviewed

Nobuaki Matsumori, Toshiyuki Yamaguchi, Yoshiko Maeta, Michio Murata

Biophysical Journal   108 ( 12 )   2816 - 2824   2015.6

Deuterium NMR of Raft Model Membranes Reveals Domain-Specific Order Profiles and Compositional Distribution Reviewed

Tomokazu Yasuda, Hiroshi Tsuchikawa, Michio Murata, Nobuaki Matsumori

Biophysical Journal   108 ( 10 )   2502 - 2506   2015.5

Modification of Bafilomycin Structure to Efficiently Synthesize Solid-State NMR Probes that Selectively Bind to Vacuolar-Type ATPase Reviewed International journal

CHEMISTRY-AN ASIAN JOURNAL   10 ( 4 )   2015.4

Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane Reviewed

Tomoya Yamamoto, Yuichi Umegawa, Hiroshi Tsuchikawa, Nobuaki Matsumori, Shinya Hanashima, Michio Murata, Resul Haser, Bernard J. Rawlings, Patrick Caffrey

Bioorganic and Medicinal Chemistry   23 ( 17 )   5782 - 5788   2015.4

Phosphatidylcholine bearing 6,6-dideuterated oleic acid: A useful solid-state H-2 NMR probe for investigating membrane properties Reviewed International journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS   25 ( 2 )   2015.1

Axial hydrogen at C7 position and bumpy tetracyclic core markedly reduce sterol's affinity to amphotericin B in membrane Reviewed

Yasuo Nakagawa, Yuichi Umegawa, Kenichi Nonomura, Naohiro Matsushita, Tetsuro Takano, Hiroshi Tsuchikawa, Shinya Hanashima, Tohru Oishi, Nobuaki Matsumori, Michio Murata

Biochemistry   54 ( 2 )   303 - 312   2015.1

Erratum Stereoselective synthesis of the head group of archaeal phospholipid PGP-Me to investigate bacteriorhodopsin-lipid interactions (Organic and Biomolecular Chemistry (015) DOI:10.1039/ c5ob01252j) Reviewed

Organic and Biomolecular Chemistry   13 ( 42 )   2015.1

Direct and Stereospecific Interaction of Amphidinol 3 with Sterol in Lipid Bilayers

BIOCHEMISTRY   53 ( 20 )   2014.5

Effect of Sterol Side Chain on Ion Channel Formation by Amphotericin B in Lipid Bilayers Reviewed International journal

BIOCHEMISTRY   53 ( 19 )   2014.5

Structure and Interaction in Lipid Bilayers Analyzed Using Bicelles Invited Reviewed

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   72 ( 5 )   2014.5

Coexistence of two liquid crystalline phases in dihydrosphingomyelin and dioleoylphosphatidylcholine binary mixtures Reviewed International journal

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES   1838 ( 5 )   2014.5

Design and Synthesis of 24-Fluorinated Bafilomycin Analogue as an NMR Probe with Potent Inhibitory Activity to Vacuolar-type ATPase Reviewed International journal

CHEMISTRY LETTERS   43 ( 4 )   2014.4

Structure and Biological Activity of 8-Deoxyheronamide C from a Marine-Derived Streptomyces sp.: Heronamides Target Saturated Hydrocarbon Chains in Lipid Membranes Reviewed International journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   136 ( 14 )   2014.4

Structure and interaction in lipid bilayers analyzed using bicelles Reviewed

Nobuaki Matsumori

Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry   72 ( 5 )   596 - 603   2014.1

Synthesis and structure revision of the C43-C67 part of amphidinol 3 Reviewed

Makoto Ebine, Mitsunori Kanemoto, Yoshiyuki Manabe, Yosuke Konno, Ken Sakai, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Organic Letters   15 ( 11 )   2846 - 2849   2013.6

Characterization of the ordered phase formed by sphingomyelin analogues and cholesterol binary mixtures Reviewed

Masanao Kinoshita, Sarah Goretta, Hiroshi Tsuchikawa, Nobuaki Matsumori, Michio Murata

Biophysics (Japan)   9   37 - 49   2013.5

Interaction between the marine sponge cyclic peptide theonellamide a and sterols in lipid bilayers as viewed by surface plasmon resonance and solid-state ²H nuclear magnetic resonance Reviewed

Rafael Atillo Espiritu, Nobuaki Matsumori, Michio Murata, Shinichi Nishimura, Hideaki Kakeya, Shigeki Matsunaga, Minoru Yoshida

Biochemistry   52 ( 14 )   2410 - 2418   2013.4

A novel sperm-activating and attracting factor from the ascidian Ascidia sydneiensis Reviewed

Nobuaki Matsumori, Yuki Hiradate, Hajime Shibata, Tohru Oishi, Shuichi Shimma, Michisato Toyoda, Fumiaki Hayashi, Manabu Yoshida, Michio Murata, Masaaki Morisawa

Organic Letters   15 ( 2 )   294 - 297   2013.1

Confirmation of the absolute configuration at C45 of amphidinol 3 Reviewed

Yoshiyuki Manabe, Makoto Ebine, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Journal of Natural Products   75 ( 11 )   2003 - 2006   2012.12

Possible conformation of amphotericin B dimer in membrane-bound assembly as deduced from solid-state NMR Reviewed

Yuichi Umegawa, Takeshi Adachi, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry   20 ( 19 )   5699 - 5704   2012.10

Effects of chemical modification of sphingomyelin ammonium group on formation of liquid-ordered phase Reviewed

Sarah A. Goretta, Masanao Kinoshita, Shoko Mori, Hiroshi Tsuchikawa, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry   20 ( 13 )   4012 - 4019   2012.7

Artificial ladder-shaped polyethers that inhibit maitotoxin-induced Ca ²⁺ influx in rat glioma C6 cells Reviewed

Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai, Futoshi Hasegawa, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry Letters   22 ( 11 )   3619 - 3622   2012.6

Head-to-tail interaction between amphotericin b and ergosterol occurs in hydrated phospholipid membrane Reviewed

Yuichi Umegawa, Yasuo Nakagawa, Kazuaki Tahara, Hiroshi Tsuchikawa, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Biochemistry   51 ( 1 )   83 - 89   2012.1

NMR-based conformational analysis of sphingomyelin in bicelles Reviewed

Toshiyuki Yamaguchi, Takashi Suzuki, Tomokazu Yasuda, Tohru Oishi, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry   20 ( 1 )   270 - 278   2012.1

Design and synthesis of sphingomyelin-cholesterol conjugates and their formation of ordered membranes Reviewed

Nobuaki Matsumori, Norio Tanada, Kohei Nozu, Hiroki Okazaki, Tohru Oishi, Michio Murata

Chemistry - A European Journal   17 ( 31 )   8568 - 8575   2011.7

Channels formed by amphotericin B covalent dimers exhibit rectification Reviewed

Minako Hirano, Yuko Takeuchi, Nobuaki Matsumori, Michio Murata, Toru Ide

Journal of Membrane Biology   240 ( 3 )   159 - 164   2011.4

Lysine proximity significantly affects glycation of lysine-containing collagen model peptides Reviewed

Asuka Kitamura, Kouta Matsui, Keiichi Konoki, Nobuaki Matsumori, Michio Murata, Toru Kawakami, Saburo Aimoto

Bioorganic and Medicinal Chemistry   19 ( 7 )   2125 - 2129   2011.4

Conformations of spermine in adenosine triphosphate complex The structural basis for weak bimolecular interactions of major cellular electrolytes Reviewed

Keisuke Maruyoshi, Toshiyuki Yamaguchi, Tetsuo Demura, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Chemistry - A European Journal   17 ( 17 )   4788 - 4795   2011.4

Synthesis of 6-F-ergosterol and its influence on membrane-permeabilization of amphotericin B and amphidinol 3 Reviewed

Yusuke Kasai, Nobuaki Matsumori, Hiroyuki Ueno, Kenichi Nonomura, Shinya Yano, Murata Michio, Tohru Oishi

Organic and Biomolecular Chemistry   9 ( 5 )   1437 - 1442   2011.3

Fluorinated cholesterol retains domain-forming activity in sphingomyelin bilayers Reviewed

Nobuaki Matsumori, Horoki Okazaki, Kaoru Nomura, Michio Murata

Chemistry and Physics of Lipids   164 ( 5 )   401 - 408   2011.1

Detection of Rap1A as a yessotoxin binding protein from blood cell membranes Reviewed

Satoru Ujihara, Tohru Oishi, Ryota Mouri, Rie Tamate, Keiichi Konoki, Nobuaki Matsumori, Michio Murata, Yasukatsu Oshima, Naoyuki Sugiyama, Masaru Tomita, Yasushi Ishihama

Bioorganic and Medicinal Chemistry Letters   20 ( 22 )   6443 - 6446   2010.11

3D structures of membrane-associated small molecules as determined in isotropic bicelles Reviewed

Nobuaki Matsumori, Michio Murata

Natural Product Reports   27 ( 10 )   1480 - 1492   2010.10

Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance Reviewed

Respati T. Swasono, Ryota Mouri, Nagy Morsy, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Bioorganic and Medicinal Chemistry Letters   20 ( 7 )   2215 - 2218   2010.4

Structural reevaluations of amphidinol 3, a potent antifungal compound from dinoflagellate Reviewed

Respati T. Swasono, Mitsunori Kanemoto, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Heterocycles   82 ( 2 )   1359 - 1369   2010.2

Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method Reviewed

Tetsuro Takano, Keiichi Konoki, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry   17 ( 17 )   6301 - 6304   2009.9

Direct interaction between amphotericin B and ergosterol in lipid bilayers as revealed by ²H NMR spectroscopy Reviewed

Nobuaki Matsumori, Kazuaki Tahara, Hiroko Yamamoto, Atsushi Morooka, Mototsugu Doi, Tohru Oishi, Michio Murata

Journal of the American Chemical Society   131 ( 33 )   11855 - 11860   2009.8

Ion channel complex of antibiotics as viewed by NMR Reviewed

Michio Murata, Yusuke Kasai, Yuichi Umegawa, Naohiro Matsushita, Hiroshi Tsuchikawa, Nobuaki Matsumori, Tohru Oishi

Pure and Applied Chemistry   81 ( 6 )   1123 - 1129   2009.7

Surface plasmon resonance-based detection of ladder-shaped polyethers by inhibition detection method Reviewed

Ryota Mouri, Tohru Oishi, Kohei Torikai, Satoru Ujihara, Nobuaki Matsumori, Michio Murata, Yasukatsu Oshima

Bioorganic and Medicinal Chemistry Letters   19 ( 10 )   2824 - 2828   2009.5

Conformational change of spermidine upon interaction with adenosine triphosphate in aqueous solution Reviewed

Keisuke Maruyoshi, Kaori Nonaka, Takeshi Sagane, Tetsuo Demura, Toshiyuki Yamaguchi, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Chemistry - A European Journal   15 ( 7 )   1618 - 1626   2009.2

Synthesis of 25- ¹³c-amphotericin B methyl ester A molecular probe for solid-state NMR measurements Reviewed

Naohiro Matsushita, Yukiko Matsuo, Hiroshi Tsuchikawa, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Chemistry Letters   38 ( 2 )   114 - 115   2009

Accurate measurement of vicinal carbon-hydrogen coupling constants via ammonium nitrogen based on HMBC experiments Reviewed

Toshiyuki Yamaguchi, Keisuke Marayoshi, Nobuaki Matsumori, Michio Murata

Chemistry Letters   37 ( 11 )   1172 - 1173   2008.12

Structure of membrane-bound amphidinol 3 in isotropic small bicelles Reviewed

Toshihiro Houdai, Nobuaki Matsumori, Michio Murata

Organic Letters   10 ( 19 )   4191 - 4194   2008.12

Structural features of dinoflagellate toxins underlying biological activity as viewed by NMR Reviewed

Michio Murata, Nobuaki Matsumori, Keiichi Konoki, Tohru Oishi

Bulletin of the Chemical Society of Japan   81 ( 3 )   307 - 319   2008.12

Interaction of ladder-shaped polyethers with transmembrane α-helix of glycophorin A as evidenced by saturation transfer difference NMR and surface plasmon resonance Reviewed

18 ( 23 )   6115 - 6118   2008.12

Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR Reviewed

Yuichi Umegawa, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Biochemistry   47 ( 51 )   13463 - 13469   2008.12

Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin Reviewed

10 ( 16 )   3599 - 3602   2008.12

Combinatorial synthesis of the 1,5-polyol system based on cross metathesis Structure revision of amphidinol 3 Reviewed

Tohru Oishi, Mitsunori Kanemoto, Respati Swasono, Nobuaki Matsumori, Michio Murata

Organic Letters   10 ( 22 )   5203 - 5206   2008.12

Design and synthesis of ladder-shaped tetracyclic, heptacyclic, and decacyclic ethers and evaluation of the interaction with transmembrane proteins Reviewed

Kohei Torikai, Tohru Oishi, Satoru Ujihara, Nobuaki Matsumori, Keiichi Konoki, Michio Murata, Saburo Aimoto

Journal of the American Chemical Society   130 ( 31 )   10217 - 10226   2008.8

Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance Reviewed

Ryota Mouri, Keiichi Konoki, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Biochemistry   47 ( 30 )   7807 - 7815   2008.7

Roles of integral protein in membrane permeabilization by amphidinols Reviewed

Nagy Morsy, Keiichi Konoki, Toshihiro Houdai, Nobuaki Matsumori, Tohru Oishi, Michio Murata, Saburo Aimoto

Biochimica et Biophysica Acta - Biomembranes   1778 ( 6 )   1453 - 1459   2008.6

Orientation of fluorinated cholesterol in lipid bilayers analyzed by ¹⁹F tensor calculation and solid-state NMR Reviewed

Nobuaki Matsumori, Yusuke Kasai, Tohru Oishi, Michio Murata, Kaoru Nomura

Journal of the American Chemical Society   130 ( 14 )   4757 - 4766   2008.4

Effects of lipid constituents on membrane-permeabilizing activity of amphidinols Reviewed

Nagy Morsy, Toshihiro Houdai, Keiichi Konoki, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Bioorganic and Medicinal Chemistry   16 ( 6 )   3084 - 3090   2008.3

Self-assembled amphotericin B is probably surrounded by ergosterol Bimolecular interactions as evidenced by solid-state NMR and CD spectra Reviewed

Yusuke Kasai, Nobuaki Matsumori, Yuichi Umegawa, Shigeru Matsuoka, Hiroyuki Ueno, Hiroki Ikeuchi, Tohru Oishi, Michio Murata

Chemistry - A European Journal   14 ( 4 )   1178 - 1185   2008.2

Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles Reviewed

Nobuaki Matsumori, Atsushi Morooka, Michio Murata

Journal of the American Chemical Society   129 ( 48 )   14989 - 14995   2007.12

Amphotericin B covalent dimers with carbonyl-amino linkage a new probe for investigating ion channel assemblies Reviewed

Yuichi Umegawa, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Tetrahedron Letters   48 ( 19 )   3393 - 3396   2007.5

Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A Reviewed

Shohei Sakuda, Nobuaki Matsumori, Kazuo Furihata, Hiromichi Nagasawa

Tetrahedron Letters   48 ( 14 )   2527 - 2531   2007.4

Conformation and position of membrane-bound amphotericin B deduced from NMR in SDS micelles Reviewed

Nobuaki Matsumori, Toshihiro Houdai, Michio Murata

Journal of Organic Chemistry   72 ( 3 )   700 - 706   2007.2

Design and synthesis of an artificial ladder-shaped polyether that interacts with glycophorin A Reviewed

Kohei Torikai, Hiroshi Yari, Megumi Mori, Satoru Ujihara, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Bioorganic and Medicinal Chemistry Letters   16 ( 24 )   6355 - 6359   2006.12

Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly ¹³C-enriched agent Reviewed

Shigeru Matsuoka, Hiroki Ikeuchi, Yuichi Umegawa, Nobuaki Matsumori, Michio Murata

Bioorganic and Medicinal Chemistry   14 ( 19 )   6608 - 6614   2006.10

Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities Reviewed

Nagy Morsy, Toshihiro Houdai, Shigeru Matsuoka, Nobuaki Matsumori, Seiji Adachi, Tohru Oishi, Michio Murata, Takashi Iwashita, Tsuyoshi Fujita

Bioorganic and Medicinal Chemistry   14 ( 19 )   6548 - 6554   2006.10

Large molecular assembly of amphotericin B formed in ergosterol-containing membrane evidenced by solid-state NMR of intramolecular bridged derivative Reviewed

Nobuaki Matsumori, Yuri Sawada, Michio Murata

Journal of the American Chemical Society   128 ( 36 )   11977 - 11984   2006.9

Synthesis of 28-¹⁹F-amphotericin B methyl ester Reviewed

Hiroshi Tsuchikawa, Naohiro Matsushita, Nobuaki Matsumori, Michio Murata, Tohru Oishi

Tetrahedron Letters   47 ( 35 )   6187 - 6191   2006.8

Detailed description of the conformation and location of membrane-bound erythromycin A using isotropic bicelles Reviewed

Nobuaki Matsumori, Atsushi Morooka, Michio Murata

Journal of Medicinal Chemistry   49 ( 12 )   3501 - 3508   2006.6

Derivatization and isotope labeling of amphotericin B aiming at elucidation of the ion-channel structure Reviewed

Nobuaki Matsumori, Tohru Oishi, Michio Murata

Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry   64 ( 5 )   502 - 513   2006.5

Ladder-shaped polyether compound, desulfated yessotoxin, interacts with membrane-integral α-helix peptides Reviewed

13 ( 17 )   5099 - 5103   2005.9

Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii Reviewed

Nagy Morsy, Shigeru Matsuoka, Toshihiro Houdai, Nobuaki Matsumori, Seiji Adachi, Michio Murata, Takashi Iwashita, Tsuyoshi Fujita

Tetrahedron   61 ( 36 )   8606 - 8610   2005.9

Bioactive fluorinated derivative of amphotericin B Reviewed

Nobuaki Matsumori, Yuichi Umegawa, Tohru Oishi, Michio Murata

Bioorganic and Medicinal Chemistry Letters   15 ( 15 )   3565 - 3567   2005.8

Mycosamine orientation of amphotericin B controlling interaction with ergosterol Sterol-dependent activity of conformation-restricted derivatives with an amino-carbonyl bridge Reviewed

Nobuaki Matsumori, Yuri Sawada, Michio Murata

Journal of the American Chemical Society   127 ( 30 )   10667 - 10675   2005.8

Hairpin conformation of amphidinols possibly accounting for potent membrane permeabilizing activities Reviewed

Toshihiro Houdai, Shigeru Matsuoka, Nagy Morsy, Nobuaki Matsumori, Masayuki Satake, Michio Murata

Tetrahedron   61 ( 11 )   2795 - 2802   2005.3

Dominant formation of a single-length channel by amphotericin B in dimyristoylphosphatidylcholine membrane evidenced by ¹³C- ³¹P rotational echo double resonance Reviewed

Shigeru Matsuoka, Hiroki Ikeuchi, Nobuaki Matsumori, Michio Murata

Biochemistry   44 ( 2 )   704 - 710   2005.1

Amphotericin B covalent dimers bearing a tartarate linkage Reviewed

Nobuaki Matsumori, Rie Masuda, Michio Murata

Chemistry and Biodiversity   1 ( 2 )   346 - 352   2004.12

Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate Reviewed

Toshihiro Houdai, Shigeru Matsuoka, Nobuaki Matsumori, Michio Murata

Biochimica et Biophysica Acta - Biomembranes   1667 ( 1 )   91 - 100   2004.11

Synthesis and conformation of deuterated spermidine for investigating weak interaction with polyanionic biomolecules Reviewed

Keisuke Maruyoshi, Tetsuo Demura, Takeshi Sagane, Nobuaki Matsumori, Tohru Oishi, Michio Murata

Tetrahedron   60 ( 24 )   5163 - 5170   2004.6

An amphotericin B-ergosterol covalent conjugate with powerful membrane permeabilizing activity Reviewed

Nobuaki Matsumori, Noritsugu Eiraku, Shigeru Matsuoka, Tohru Oishi, Michio Murata, Takaaki Aoki, Toru Ide

Chemistry and Biology   11 ( 5 )   673 - 679   2004.5

Amphotericin B-phospholipid covalent conjugates Dependence of membrane-permeabilizing activity on acyl-chain length Reviewed

Shigeru Matsuoka, Nobuaki Matsumori, Michio Murata

Organic and Biomolecular Chemistry   1 ( 22 )   3882 - 3884   2003.11

Amphotericin B Dimers with Bisamide Linkage Bearing Powerful Membrane-Permeabilizing Activity Reviewed

Nahoko Yamaji, Nobuaki Matsumori, Shigeru Matsuoka, Tohru Oishi, Michio Murata

Organic Letters   4 ( 12 )   2087 - 2089   2002.6

Amphotericin B covalent dimers forming sterol-dependent ion-permeable membrane channels Reviewed

Nobuaki Matsumori, Nahoko Yamaji, Shigeru Matsuoka, Tohru Oishi, Michio Murata

Journal of the American Chemical Society   124 ( 16 )   4180 - 4181   2002.4

Absolute configuration of aflastatin A, a specific inhibitor of aflatoxin production by Aspergillus parasiticus Reviewed

Hiroyuki Ikeda, Nobuaki Matsumori, Makoto Ono, Akinori Suzuki, Akira Isogai, Hiromichi Nagasawa, Shohei Sakuda

Journal of Organic Chemistry   65 ( 2 )   438 - 444   2000.1

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region Reviewed

Nobuaki Kudo, Nobuaki Matsumori, Hiroshi Taoka, Daisuke Fujiwara, Erwin P. Schreiner, Barbara Wolff, Minoru Yoshida, Sueharu Horinouchi

Proceedings of the National Academy of Sciences of the United States of America   96 ( 16 )   9112 - 9117   1999.8

Absolute configuration of amphidinol 3, the first complete structure determination from amphidinol homologues Application of a new configuration analysis based on carbon-hydrogen spin-coupling constants [8] Reviewed

Michio Murata, Shigeru Matsuoka, Nobuaki Matsumori, Gopal K. Paul, Kazuo Tachibana

Journal of the American Chemical Society   121 ( 4 )   870 - 871   1999.2

Stereochemical determination of acyclic structures based on carbon- proton spin-coupling constants. A method of configuration analysis for natural products Reviewed

Nobuaki Matsumori, Daisuke Kaneno, Michio Murata, Hideshi Nakamura, Kazuo Tachibana

Journal of Organic Chemistry   64 ( 3 )   866 - 876   1999.2

Absolute structure and total synthesis of lipogrammistin-A, a lipophilic ichthyotoxin of the soapfish Reviewed

Hiroyuki Onuki, Kei Ito, Yoshimasa Kobayashi, Nobuaki Matsumori, Kazuo Tachibana, Nobuhiro Fusetani

Journal of Organic Chemistry   63 ( 12 )   3925 - 3932   1998.6

Analysis of relative configuration of acyclic compounds based on long-range carbon-proton coupling constants determined by two dimensional NMR Reviewed

Michio Murata, Nobuaki Matsumori, Kazuo Tachibana

Unknown Journal   ( 11 )   749 - 757   1997.1

Involvement of AfsA in A-factor biosynthesis as a key enzyme Reviewed

Noriko Ando, Nobuaki Matsumori, Shohei Sakuda, Teruhiko Beppu, Sueharu Horinouchi

Journal of Antibiotics   50 ( 10 )   847 - 852   1997.1

Chemical structures of amphidinols 5 and 6 isolated from marine dinoflagellate Amphidinium klebsii and their cholesterol-dependent membrane disruption Reviewed

Gopal K. Paul, Nobuaki Matsumori, Keiichi Konoki, Michio Murata, Kazuo Tachibana

Journal of Marine Biotechnology   5 ( 2-3 )   124 - 128   1997

Long-range carbon-proton coupling constants for stereochemical assignment of acyclic structures in natural products Configuration of the C5-C9 portion of maitotoxin Reviewed

Nobuaki Matsumori, Taro Nonomura, Makoto Sasaki, Michio Murata, Kazuo Tachibana, Masayuki Satake, Takeshi Yasumoto

Tetrahedron Letters   37 ( 8 )   1269 - 1272   1996.2

The Complete Structure of Maitotoxin, Part II Configuration of the C135-C142 Side Chain and Absolute Configuration of the Entire Molecule Reviewed

Taro Nonomura, Makoto Sasaki, Nobuaki Matsumori, Michio Murata, Kazuo Tachibana, Takeshi Yasumoto

Angewandte Chemie (International Edition in English)   35 ( 15 )   1675 - 1678   1996.1

The Complete Structure of Maitotoxin, Part I Configuration of the C1-C14 Side Chain Reviewed

Makoto Sasaki, Nobuaki Matsumori, Takahiro Maruyama, Taro Nonomura, Michio Murata, Kazuo Tachibana, Takeshi Yasumoto

Angewandte Chemie (International Edition in English)   35 ( 15 )   1672 - 1675   1996.1

Stereochemical assignment of the C35-C39 Acyclic linkage in maitotoxin completion of stereochemical determination of C15-C134 Reviewed

Makoto Sasaki, Nobuaki Matsumori, Michio Murata, Kazuo Tachibana, Takeshi Yasumoto

Tetrahedron Letters   36 ( 49 )   9011 - 9014   1995.12

Conformational analysis of natural products using long-range carbon-proton coupling constants Three-dimensional structure of okadaic acid in solution Reviewed

Nobuaki Matsumori, Michio Murata, Kazuo Tachibana

Tetrahedron   51 ( 45 )   12229 - 12238   1995.11

Isolation and chemical structure of amphidinol 2, a potent hemolytic compound from marine dinoflagellate Amphidinium klebsii Reviewed

Gopal K. Paul, Nobuaki Matsumori, Michio Murata, Kazuo Tachibana

Tetrahedron Letters   36 ( 35 )   6279 - 6282   1995.8

脂質機能解明のための多角的分析 Invited

松森信明

脂質駆動学術産業創生研究部会  2022.12 

Interaction Analysis between Membrane Proteins and Lipids Invited International conference

Nobuaki Matsumori

ICPAC Kotakinabalu 2022  2022.11 

脂質と膜タンパク質の相互作用解析法の開発とその応用 Invited

松森信明

公益財団法人山田科学振興財団 2022年度研究交歓会  2022.10 

Interaction analysis between membrane proteins and lipids towards elucidation of lipid-related chemical communications International conference

Nobuaki Matsumori

Pacifichem2021  2021.12 

脂質ラフトと麻酔作用 Invited

松森信明

麻酔メカニズム研究会  2021.12 

Interaction analysis between membrane proteins and lipids to understand biological membranes Invited

Nobuaki Matsumori

The 59th Japanese Biophysical Society Meeting  2021.11 

脂質－膜タンパク質相互作用解析法の開発とその応用 Invited

松森信明

新学術領域研究「化学コミュニケーションのフロンティア」第8回公開シンポジウム  2021.7 

局所麻酔の新たなメカニズム Invited

松森信明

ペインクリニック学会第５４回学術集会  2020.11 

脂質膜における各種相互作用の解析 Invited

松森信明

生体膜を含む生体分子間相互作用研究の現状と課題  2019.8 

Development of novel fluorescent analogs of sphingomyelins, ceramide, and hybrid phosphatidylcholines. International conference

Takaaki Matsufuji, Kana Hirano, Yutaro Tajima, Masanao Kinoshita, and Nobuaki Matsumori

The International Conference on the Bioscience of Lipids (ICBL)  2019.6 

膜タンパク質―脂質相互作用解析法の開発：脂質ケミカルバイオロジー創成に向けて

#稲田壮峰、木下祥尚、松森信明

日本ケミカルバイオロジー学会　第14回年会  2019.6 

Integrated Analysis of Membrane Systems Invited International conference

Nobuaki Matsumori

International Seminar on Biophysics and Chemical Biology of Biomembrane and Lipid Bilayers  2017.10 

NMR and Fluorescent Studies of Lipid Rafts Invited International conference

Nobuaki Matsumori, Masanao Kinoshita

9th Korea-Japan Seminars on Biomolecular Sciences: Experimental and Simulations  2016.11 

脂質膜における動的挙動、構造および相互作用解析 Invited

松森 信明

蛋白研セミナー Mechanism of Biology of Membrane: 生体膜上の生物化学  2016.3 

脂質ラフト形成基盤の解明を目指したスフィンゴミエリンの動的およびNMR構造解析 Invited

松森 信明

日本化学会第96春季年会、ケミカルバイオロジーの新機軸ー機器分析とライフイノベーション  2016.3 

脂質ラフトにおける脂質分子の動的挙動および構造解析 Invited

松森 信明

第88回日本生化学会大会フォーラム  2015.12 

脂質膜の統合分析 Invited

松森 信明

第33回九州コロイドコロキウム  2015.11 

脂質ラフトのNMR解析 Invited

松森 信明

第53回日本生物物理学会年会  2015.9 

生体膜の統合分析を目指して Invited

松森 信明

統合分析・生物化学研究特区公開講演会  2015.3 

脳分子解析のための超高感度キャピラリー電気泳動-質量分析法の開発と応用

猪狩 世玲菜, 劉 晨晨, 木下 祥尚, 松森 信明, 淺野 紘史, 宮田 茂雄, 上田 修平, 竹本 さやか, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

神経芽腫細胞を用いた局所麻酔薬による脂質ラフトの形成抑制(Local anesthetics suppress the formation of lipid rafts in mouse neuroblastoma(Neuro2a) cell membranes)

Nishimura Aoi, Tanaka Yasuhiro, Kinoshita Masanao, Torikai Kohei, Kawai Takayuki, Matsumori Nobuaki

生物物理  2023.10  (一社)日本生物物理学会

生体膜マイクロドメインを標的とした微量脂質分析法の開発

久保田 颯, 伊藤 美由紀, 今田 皇緑, 劉 晨晨, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

液体クロマトグラフィー/キャピラリー電気泳動二次元糖鎖解析法の開発

三木 太陽, 劉 晨晨, 木下 祥尚, 松森 信明, 山本 佐知雄, 木下 充弘, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

脳分子解析のための超高感度キャピラリー電気泳動-質量分析法の開発と応用

猪狩 世玲菜, 劉 晨晨, 木下 祥尚, 松森 信明, 淺野 紘史, 宮田 茂雄, 上田 修平, 竹本 さやか, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

細胞破裂に基づく簡便な生体膜透過性評価法

猪狩 世玲菜, 劉 晨晨, 鳥飼 浩平, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2023.9  (公社)日本分析化学会

糖脂質糖鎖を対象とした超高感度キャピラリー電気泳動分析法の開発

何 甦恩, 三木 太陽, 劉 晨晨, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2023.9  (公社)日本分析化学会

神経芽腫細胞を用いた局所麻酔薬による脂質ラフトの形成抑制(Local anesthetics suppress the formation of lipid rafts in mouse neuroblastoma(Neuro2a) cell membranes)

Nishimura Aoi, Tanaka Yasuhiro, Kinoshita Masanao, Torikai Kohei, Kawai Takayuki, Matsumori Nobuaki

生物物理  2023.10  (一社)日本生物物理学会

生体膜局所の定量的脂質プロファイリングに向けたマイクロニードル固相抽出　質量分析法の開発

久保田 颯, 伊藤 美由紀, 劉 晨晨, 鳥飼 浩平, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2023.9  (公社)日本分析化学会

生体膜マイクロドメインを標的とした微量脂質分析法の開発

久保田 颯, 伊藤 美由紀, 今田 皇緑, 劉 晨晨, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

液体クロマトグラフィー/キャピラリー電気泳動二次元糖鎖解析法の開発

三木 太陽, 劉 晨晨, 木下 祥尚, 松森 信明, 山本 佐知雄, 木下 充弘, 川井 隆之

日本分析化学会講演要旨集  2022.9  (公社)日本分析化学会

核酸医薬品を対象とした超高感度キャピラリー電気泳動-質量分析の開発

山下 愛斗, 藤村 泰地, 劉 晨晨, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2023.9  (公社)日本分析化学会

一細胞薬物動態解析に向けた超高感度CE-MS分析法の開発

藤村 泰地, 劉 晨晨, 鳥飼 浩平, 木下 祥尚, 松森 信明, 川井 隆之

日本分析化学会講演要旨集  2023.9  (公社)日本分析化学会

日本ケミカルバイオロジー学会

The Biophysical Society of Japan

THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN

THE CHEMICAL SOCIETY OF JAPAN

THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY

American Chemical Society,

Biophysical Society

Organizer   Domestic

2015.4 - 2020.3   

日本分析化学会　九州支部   常任幹事   Domestic

2015.4 - 2016.3   

Screening of academic papers

Role(s)： Peer review

2021

実行委員会

第15回ケミカルバイオロジー学会年会  （ 九州大学 ） 2020.6

Screening of academic papers

Role(s)： Peer review

2020

実行委員会

第79回分析化学討論会  （ 北九州 ） 2019.5

Screening of academic papers

Role(s)： Peer review

2019

Screening of academic papers

Role(s)： Peer review

2018

座長 International contribution

（ 大阪大学 ） 2017.10

Screening of academic papers

Role(s)： Peer review

2017

座長（Chairmanship）

日本分析化学会第６５年会  （ 北海道大学工学部 ） 2016.9

科研費審査

Role(s)： Review, evaluation

日本学術振興会  2016.4 - 2017.3

実行委員

日本分析化学会第６４年会  （ 福岡市西区　九州大学伊都キャンパス ） 2015.9

座長（Chairmanship）

日本化学会年会  （ 名古屋 ） 2014.3

脂質が関与する化学コミュニケーション解明のための脂質認識天然物リガンドの探索

Grant number：20H04781  2020 - 2021

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

脂質特異的タンパク質の網羅的解析法の開発

2020 - 2021

山田科学振興財団 研究援助

脂質が関与する化学コミュニケーション解明のための脂質認識天然物リガンドの探索

Grant number：20H04781  2020

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究（研究領域提案型）

脂質ラフト阻害アッセイ法の開発と阻害剤の探索

Grant number：18K19149  2018 - 2019

日本学術振興会  科学研究費助成事業  挑戦的研究（萌芽）

蛍光標識脂質を用いた脂質膜の動的秩序解析

2016.3 - 2018.3

日本 

蛍光標識脂質を用いた脂質膜の動的秩序解析

Grant number：16H00773  2016 - 2017

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

脂質ケミカルバイオロジーの創出

2015.4 - 2018.3

九州大学 

脂質ケミカルバイオロジーの創成

Grant number：15H03121  2015 - 2017

日本学術振興会  科学研究費助成事業  基盤研究(B)

脂質ラフトにおける脂質分子の動的秩序解析

2014.4 - 2016.3

海産梯子状ポリエーテル化合物イェッソトキシンの標的分子

2014.4 - 2016.3

海産梯子状ポリエーテル化合物イェッソトキシンの標的分子

Grant number：26102731  2014 - 2015

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

脂質ラフトにおける脂質分子の動的秩序解析

Grant number：26102527  2014 - 2015

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

生体膜構成脂質の機能を探る小分子の再発見と作用機構の解明

2013.5 - 2017.3

生体膜構成脂質の機能を探る小分子の再発見と作用機構の解明

Grant number：25242073  2013 - 2017

日本学術振興会  科学研究費助成事業  基盤研究(A)

ERATO脂質構造活性プロジェクト

2011.4 - 2016.3

大阪大学 

化学特別講義Ⅳ

2023.4 - 2023.9   First semester

分析化学Ⅲ

2023.4 - 2023.9   First semester

分析化学特論ⅡA

2023.4 - 2023.6   Spring quarter

Advanced Analytical Chemistry ⅡA

2023.4 - 2023.6   Spring quarter

化学序説Ⅱ

2022.10 - 2023.3   Second semester

化学序説Ⅰ

2022.4 - 2022.9   First semester

分析化学Ⅲ

2022.4 - 2022.9   First semester

分析化学Ⅰ

2022.4 - 2022.9   First semester

化学序説（R3年度入学者及び2年次未進級者用）

2021.4 - 2022.3   Full year

分析化学Ⅲ

2021.4 - 2021.9   First semester

分析化学Ⅰ

2021.4 - 2021.9   First semester

分析化学特論ⅡA

2021.4 - 2021.6   Spring quarter

化学特別講義Ⅵ

2020.4 - 2021.3   Full year

分析化学Ⅲ

2020.4 - 2020.9   First semester

分析化学Ⅰ

2020.4 - 2020.9   First semester

分析化学Ⅰ

2019.4 - 2019.9   First semester

分析化学Ⅲ

2019.4 - 2019.9   First semester

分析化学特論Ⅱ

2019.4 - 2019.9   First semester

分析化学特論II

2019.4 - 2019.9   First semester

分析化学III

2019.4 - 2019.9   First semester

分析化学I

2019.4 - 2019.9   First semester

分析化学Ⅲ

2018.4 - 2018.9   First semester

化学序説

2018.4 - 2018.9   First semester

分析化学Ⅰ

2018.4 - 2018.9   First semester

身の回りの化学

2017.12 - 2018.2   Winter quarter

身の回りの化学

2017.10 - 2017.12   Fall quarter

分析化学Ⅲ

2017.4 - 2017.9   First semester

分析化学特論Ⅱ

2017.4 - 2017.9   First semester

分析化学Ⅰ

2017.4 - 2017.9   First semester

身の回りの化学

2016.12 - 2017.2   Winter quarter

分析化学III

2016.4 - 2016.9   First semester

分析化学I

2016.4 - 2016.9   First semester

身の回りの化学

2015.12 - 2016.2   Winter quarter

分析化学III

2015.10 - 2016.3   Second semester

身の回りの化学

2015.10 - 2015.12   Fall quarter

分析化学I

2015.4 - 2015.9   First semester

分析化学特論II

2015.4 - 2015.9   First semester

分析化学学生実験

2014.10 - 2015.3   Second semester

分析化学III

2014.10 - 2015.3   Second semester

2020.12   Role：Participation   Title：新型コロナウィルス感染拡大状況での学生のメンタルヘルス

Organizer：[Undergraduate school/graduate school/graduate faculty]

2020.11   Role：Participation   Title：事件等発生時の学生対応に関するＦＤ・ＳＤ

Organizer：University-wide

2018.9   Role：Participation   Title：M2B システムFD

Organizer：[Undergraduate school/graduate school/graduate faculty]

2018.3   Role：Moderator   Title：学生に起こりやすい問題とその対応ー発達障害を中心にー

Organizer：Undergraduate school department

2016.2   Role：Participation   Title：化学部門ＦＤ

Organizer：Undergraduate school department

2019  Class Teacher 

2018  Class Teacher 

2017  Class Teacher 

2017  Special Affairs 

2016  Class Teacher 

2015  Class Teacher 

2014  Class Teacher 

局所麻酔薬が脂質ラフトを破壊 ～麻酔作用発現に関する新たなメカニズムの提案～

九州大学よりプレスリリース https://www.kyushu-u.ac.jp/ja/researches/view/349  九州大学  2019.6

膜タンパク質の働きに深く関わる脂質を簡便に特定する方法の開発に成功 〜多様な脂質の生理機能の解明や医薬品開発に期待〜

九州大学よりプレスリリースhttps://www.kyushu-u.ac.jp/ja/researches/view/320  九州大学  2019.2

肌の保湿バリア機能を示す成分であるセラミドの挙動をありのままに観察できる蛍光分子の開発に世界で初めて成功 - セラミドの機能解明につながる新たなツールとして期待 -

九州大学よりプレスリリース https://www.kyushu-u.ac.jp/ja/researches/view/317  九州大学  2019.2

九州大学オープンキャンパス　理学部化学科紹介プログラム 「毒や薬から脂質膜までの分析化学」

九州大学  九州大学伊都キャンパス  2017.8

身の回りの化学物質：においや味から薬や毒まで

山口県立徳山高校  2017.2

化学科後期特別談話会　「脂質膜の統合分析を目指して　脂質ケミカルバイオロジー」

九州大学理学部化学科  九州大学  2016.12

化学科前期特別談話会　 脂質膜の統合分析を目指して　バイセルを用いたアプローチ

九州大学理学部化学科  九州大学  2014.12

2014, 2015年度　大学入試センター試験問題作成委員

2014.4