Updated on 2024/10/09

Information

 

写真a

 
LIU CHENCHEN
 
Organization
Faculty of Science Department of Chemistry Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス

Degree

  • University of Shanghai for Science and Technology, Doctoral Degree

  • Kyoto University, Doctoral Degree

Research History

  • 2021年10月 - 2022年03月 京都大学 大学院工学研究科 材料化学専攻 ポスドク 2016年10月 - 2018年10月 華東理工大学 ポスドク

    2021年10月 - 2022年03月 京都大学 大学院工学研究科 材料化学専攻 ポスドク 2016年10月 - 2018年10月 華東理工大学 ポスドク

Awards

  • 第74回日本電気泳動学会学術大会 一般演題優秀賞

    2023.5   第74回日本電気泳動学会学術大会   Online fluorescent imaging method for improving the accuracy of quantitative capillary electrophoresis

Papers

  • Recent advances in microscale separation techniques for glycome analysis Invited Reviewed

    Chenchen Liu, Koji Otsuka, Takayuki Kawai

    Journal of Separation Science   47 ( 11 )   e2400170   2024.6   ISSN:1615-9306 eISSN:1615-9314

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    The glycomic analysis holds significant appeal due to the diverse roles that glycans and glycoconjugates play, acting as modulators and mediators in cellular interactions, cell/organism structure, drugs, energy sources, glyconanomaterials, and more. The glycomic analysis relies on liquid‐phase separation technologies for molecular purification, separation, and identification. As a miniaturized form of liquid‐phase separation technology, microscale separation technologies offer various advantages such as environmental friendliness, high resolution, sensitivity, fast speed, and integration capabilities. For glycan analysis, microscale separation technologies are continuously evolving to address the increasing challenges in their unique manners. This review discusses the fundamentals and applications of microscale separation technologies for glycomic analysis. It covers liquid‐phase separation technologies operating at scales generally less than 100 µm, including capillary electrophoresis, nanoflow liquid chromatography, and microchip electrophoresis. We will provide a brief overview of glycomic analysis and describe new strategies in microscale separation and their applications in glycan analysis from 2014 to 2023.

    DOI: 10.1002/jssc.202400170

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  • Development of transient trapping micellar electrokinetic chromatography coupled with mass spectrometry for steroids analysis Invited Reviewed International journal

    Yanawut Manmana, Chenchen Liu, Hiroshi Koino, Kenji Sueyoshi, Fumihiko Kitagawa, Takuya Kubo*, Koji Otsuka

    Chirality   34 ( 10 )   1328 - 1337   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/chir.23489

  • Specific recognition of a target protein, cytochrome c, using molecularly imprinted hydrogels Reviewed International journal

    Chenchen Liu, Takuya Kubo, Koji Otsuka

    Journal of Materials Chemistry B   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d2tb00501h

  • Fluorescent detection of target proteins via a molecularly imprinted hydrogel

    Takuya Kubo, Naoki Watanabe, Seiji Ikari, Chenchen Liu, Eisuke Kanao, Toyohiro Naito, Tomoharu Sano, Koji Otsuka

    ANALYTICAL METHODS   13 ( 27 )   3086 - 3091   2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d0ay02341h

  • Hydrogels in Electrophoresis: Applications and Advances

    Chenchen Liu, Takuya Kubo, Koji Otsuka

    ANALYTICAL SCIENCES   37 ( 6 )   807 - 816   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2116/analsci.20R004

  • Online fluorescence imaging method by reducing the inequivalent photobleaching for quantitative capillary electrophoresis

    Chenchen Liu, Yoshinori Yamaguchi, Yi Wang, Xiaoming Dou, Takuya Kubo, Koji Otsuka

    SENSORS AND ACTUATORS B-CHEMICAL   319   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.snb.2020.128035

  • Controllable Molecular Sieving by copoly(Poly(ethylene glycol) Acrylate/Poly(ethylene glycol) Diacrylate)-Based Hydrogels via Capillary Electrophoresis for DNA Fragments

    Chenchen Liu, Takuya Kubo, Toyohiro Naito, Koji Otsuka

    ACS Applied Polymer Materials   2 ( 9 )   3886 - 3893   2020.9

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsapm.0c00567

  • Rapid and quantitative detection of trace Sudan black B in dyed black rice by surface-enhanced Raman spectroscopy (SERS)

    Yubin Zhao, Yoshinori Yamaguchi, Chenchen Liu, Mingda Li, Xiaoming Dou

    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY   216   202 - 206   2019.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.saa.2019.03.030

  • Precise and simultaneous enumeration of multiplex pathogens using multiplex polymer chain reaction coupled with a novel quantitative capillary electrophoresis

    Liu, C., Yamaguchi, Y., Sekine, S., Ni, Y., Dou, X.

    Sensors and Actuators, B: Chemical   258   2018.4

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.snb.2017.11.106

  • Quantitative Detection of Ethanol/Acetone in Complex Solutions Using Raman Spectroscopy Based on Headspace Gas Analysis

    Yubin Zhao, Yoshinori Yamaguchi, Chenchen Liu, Shinichi Sekine, Xiaoming Dou

    APPLIED SPECTROSCOPY   72 ( 2 )   280 - 287   2018.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/0003702817738010

  • Analysis of Capillary Electrophoresis Noise Characteristics

    Chen, G., Zhu, X.-F., Dou, X.-M., Liu, C.-C., Xu, Q.-Q., Yamaguchi, Y., Ni, Y.

    Guangzi Xuebao/Acta Photonica Sinica   46 ( 6 )   2017.6

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.3788/gzxb20174606.0612004

  • Molecular sieving polymer for DNA/RNA separation in capillary electrophoresis

    Liu, C., Yamaguchi, Y., Dou, X.

    International Journal of Modern Physics B   31 ( 16-19 )   2017.5

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1142/S0217979217440945

  • Effective length calibration method for processing the fluorescence signal detected by charge-coupled device in capillary electrophoresis

    Ni, Y., Liu, C., Chen, J., Chen, Q., Zhu, X., Dou, X.

    Journal of Separation Science   40 ( 9 )   2017.3

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jssc.201601458

  • Rapid identification and quantitation for oral bacteria based on short-end capillary electrophoresis

    Chen, J., Ni, Y., Liu, C., Yamaguchi, Y., Chen, Q., Sekine, S., Zhu, X., Dou, X.

    Talanta   160   2016.11

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.talanta.2016.07.049

  • Analysis of the inhibition of nucleic acid dyes on polymerase chain reaction by capillary electrophoresis

    Li, Z., Liu, C., Ma, S., Zhang, D., Yamaguchi, Y.

    Analytical Methods   8 ( 11 )   2016.2

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c5ay02705e

  • Capillary electrophoresis of RNA in hydroxyethylcellulose polymer with various molecular weights

    Li, Z., Liu, C., Zhang, D., Luo, S., Yamaguchi, Y.

    Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences   1011   2016.1

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jchromb.2015.12.057

  • Gene analysis of multiple oral bacteria by the polymerase chain reaction coupled with capillary polymer electrophoresis

    Liu, C., Yamaguchi, Y., Sekine, S., Ni, Y., Li, Z., Zhu, X., Dou, X.

    Journal of Separation Science   39 ( 5 )   2015.12

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jssc.201501087

  • Theoretical investigation on the performance of DNA electrophoresis under programmed step electric field strength: Two-step condition

    Ni, Y., Liu, C., Chen, Q., Zhu, X., Dou, X.

    Journal of Separation Science   38 ( 20 )   2015.10

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jssc.201500640

  • Polyethylene Oxide (PEO) and Polyethylene Glycol (PEG) Polymer Sieving Matrix for RNA Capillary Electrophoresis (vol 10, e0123406, 2015)

    Yoshinori Yamaguchi, Zhenqing Li, Xifang Zhu, Chenchen Liu, Dawei Zhang, Xiaoming Dou

    PLOS ONE   10 ( 6 )   2015.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0131265

  • Analysis of small interfering RNA by capillary electrophoresis in hydroxyethylcellulose solutions

    Liu, C., Yamaguchi, Y., Zhu, X., Zhenqing, L., Ni, Y., Dou, X.

    Electrophoresis   36 ( 14 )   2015.4

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/elps.201500018

  • Quantification of Periodontal Pathogens Cell Counts by Capillary Electrophoresis

    Li, Z., Chen, S., Liu, C., Zhang, D., Dou, X., Yamaguchi, Y.

    Journal of Chromatography A   1361   2014.8

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.chroma.2014.07.100

  • Electromigration behavior of nucleic acids in capillary electrophoresis under pulsed-field conditions

    Li, Z., Liu, C., Dou, X., Ni, Y., Wang, J., Yamaguchi, Y.

    Journal of Chromatography A   1331   2014.3

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.chroma.2014.01.021

  • Capillary electrophoresis of a wide range of DNA fragments in a mixed solution of hydroxyethyl cellulose

    Li, Z., Liu, C., Yamaguchi, Y., Ni, Y., You, Q., Dou, X.

    Analytical Methods   6 ( 8 )   2014.1

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c3ay41965g

  • Capillary electrophoresis of DNA in hydroxyethylcellulose

    Liu, C., Li, Z., Meng, F., Ni, Y., Dou, X., Yoshinori, Y.

    Acta Chimica Sinica   71 ( 2 )   2012.12

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.6023/A12110935

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Research Projects

  • Single-cell Mitochondria Analysis using Molecularly Imprinted Material

    Grant number:23K13776  2023 - 2024

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Early-Career Scientists

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • Functionalized capillary device for mass spectrometry-based subcellular lipid profiling

    Grant number:22K20560  2022 - 2023

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Research Activity start-up

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 分子認識PEGゲルキャピラリー電気泳動による生体分子の構造・サイズ選択的分離

    Grant number:20J15151  2020 - 2021

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • キャピラリー電気泳動の分離性能の向上の研究-新しいポリマーゲルを使用した一本鎖コンフォメーション多型(google translation)

    Grant number:21804042  2017 - 2021

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding