Updated on 2024/07/28

Information

 

写真a

 
HAYASHI YOSHIKI
 
Organization
Faculty of Science Department of Biology Lecturer
School of Sciences Department of Biology（Concurrent）
Graduate School of Systems Life Sciences Department of Systems Life Sciences（Concurrent）
Title
Lecturer
External link

Degree

  • Ph.D

Research Interests・Research Keywords

  • Research theme：“Germline” is the central cell lineage responsible for reproduction. By using an ideal genetic model organism, Drosophila, we are tackling to reveal the mystery of germline. During its developmental processes, germline possesses similar characteristics as multi-potent stem cells, and has a states of tissue stem cells. Since of those, germline research could contribute to understand not only for germline development, but also stem cell regulation. By investigating Drosophila germline, we try to understand the processes of cell differentiation, mechanisms of stem cell regulation and aging, in addition to reveal the mystery of germline.

    Keyword：Germline Drosophila Cellular-metabolism Epigenetic

    Research period： 2023.10 - 2028.10

Awards

  • Best Poster Award

    2018.1   KEY Forum: The 3rd International Symposium on Stem Cell Traits and Developmental Systems  

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    Best Poster Award of KEY Forum: The 3rd International Symposium on Stem Cell Traits and Developmental Systems

Papers

  • Differential heparan sulfate-dependency of the Drosophila glypicans

    Eriko Nakato, Keisuke Kamimura, Collin Knudsen, Suzuka Masutani, Masahiko Takemura, Yoshiki Hayashi, Takuya Akiyama, Hiroshi Nakato

    Journal of Biological Chemistry   105544   2023.12

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    Language：Others   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jbc.2023.105544

  • Mechanism underlying retinoic acid-dependent metamorphosis in the starfish International journal

    Yamakawa, Shumpei, Hayashi, Yoshiki, Kako, Koichiro, Sasakura, Yasunori, Morino, Yoshiaki, Wada, Hiroshi

    Developmental biology   2022.10

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    Language：English   Publishing type：Research paper (scientific journal)  

    Mechanism underlying retinoic acid-dependent metamorphosis in the starfish
    The evolution of the biphasic life cycle in marine invertebrates has attracted considerable interest in zoology. We recently provided evidence that retinoic acid (RA) is involved in the regulation of metamorphosis in starfish. It also functions in life cycle transitions of jellyfish (cnidaria). Thus, documenting the evolutionarily conserved role of RA in such transitions will help to trace the life cycle evolution of bilaterians and cnidarians. In this study, we examined the molecular mechanisms by which RA signaling is involved in the commencement of metamorphosis in starfish. First, we measured RA levels during the larval and metamorphosis stages by liquid chromatography-tandem mass spectrometry. We found that all-trans RA levels in the larval body are high before larvae acquire competence for metamorphosis, suggesting that the commencement of metamorphosis is not controlled by increased RA synthesis. Furthermore, the suppression of rar gene expression by TALEN-mediated gene knockout revealed that RA receptor (RAR) is essential for metamorphosis. These observations suggest that the initiation of metamorphosis is regulated at the level of synthesized RA to activate RAR. We discuss

    DOI： 10.1016/j.ydbio.2022.10.002

  • Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis Reviewed

    Hayashi, Yoshiki, Kashio, Soshiro, Murotomi, Kazutoshi, Hino, Shinjiro, Kang, Woojin, Miyado, Kenji, Nakao, Mitsuyoshi, Miura, Masayuki, Kobayashi, Satoru, Namihira, Masakazu

    Scientific reports   12 ( 1 )   5593   2022.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis
    Tissue aging is a major cause of aging-related disabilities and a shortened life span. Understanding how tissue aging progresses and identifying the factors underlying tissue aging are crucial; however, the mechanism of tissue aging is not fully understood. Here we show that the biosynthesis of S-adenosyl-methionine (SAM), the major cellular donor of methyl group for methylation modifications, potently accelerates the aging-related defects during Drosophila oogenesis. An aging-related increase in the SAM-synthetase (Sam-S) levels in the germline leads to an increase in ovarian SAM levels. Sam-S-dependent biosynthesis of SAM controls aging-related defects in oogenesis through two mechanisms, decreasing the ability to maintain germline stem cells and accelerating the improper formation of egg chambers. Aging-related increases in SAM commonly occur in mouse reproductive tissue and the brain. Therefore, our results raise the possibility suggesting that SAM is the factor related to tissue aging beyond the species and tissues.

    DOI： 10.1038/s41598-022-09424-1

  • Heparan sulfate proteoglycan molecules, syndecan and perlecan, have distinct roles in the maintenance of Drosophila germline stem cells Reviewed

    Hayashi, Yoshiki, Shibata, Arisa, Kamimura, Keisuke, Kobayashi, Satoru

    DEVELOPMENT GROWTH & DIFFERENTIATION   63 ( 6 )   295 - 305   2021.8

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    Heparan sulfate proteoglycan molecules, syndecan and perlecan, have distinct roles in the maintenance of Drosophila germline stem cells
    The Drosophila female germline stem cell (GSC) niche provides an excellent model for understanding the stem cell niche in vivo. The GSC niche is composed of stromal cells that provide growth factors for the maintenance of GSCs and the associated extracellular matrix (ECM). Although the function of stromal cells/growth factors has been well studied, the function of the ECM in the GSC niche is largely unknown. In this study, we investigated the function of syndecan and perlecan, molecules of the heparan sulfate proteoglycan (HSPG) family, as the main constituents of the ECM. We found that both of these genes were expressed in niche stromal cells, and knockdown of them in stromal cells decreased GSC number, indicating that these genes are important niche components. Interestingly, our genetic analysis revealed that the effects of syndecan and perlecan on the maintenance of GSC were distinct. While the knockdown of perlecan in the GSC niche increased the number of cystoblasts, a phenotype suggestive of delayed differentiation of GSCs, the same was not true in the context of syndecan. Notably, the overexpression of syndecan and perlecan did not cause an expansion of the GSC niche, opposing the results reported in the context of glypican, another HSPG gene. Altogether, our data suggest that HSPG genes contribute to the maintenance of GSCs through multiple mechanisms, such as the control of signal transduction, and ligand distribution/stabilization. Therefore, our study paves the way for a deeper understanding of the ECM functions in the stem cell niche.

    DOI： 10.1111/dgd.12741

  • Suppression of Non-Random Fertilization by MHC Class I Antigens Reviewed International journal

    Kamiya, Junki, Kang, Woojin, Yoshida, Keiichi, Takagi, Ryota, Kanai, Seiya, Hanai, Maito, Nakamura, Akihiro, Yamada, Mitsutoshi, Miyamoto, Yoshitaka, Miyado, Mami, Kuroki, Yoko, Hayashi, Yoshiki, Umezawa, Akihiro, Kawano, Natsuko, Miyado, Kenji

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   21 ( 22 )   2020.11

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    Suppression of Non-Random Fertilization by MHC Class I Antigens
    Hermaphroditic invertebrates and plants have a self-recognition system on the cell surface of sperm and eggs, which prevents their self-fusion and enhances non-self-fusion, thereby contributing to genetic variation. However, the system of sperm-egg recognition in mammals is under debate. To address this issue, we explored the role of major histocompatibility complex class I (MHC class I, also known as histocompatibility 2-Kb or H2-Kb and H2-Db in mice) antigens by analyzing H2-Kb-/-H2-Db-/-β2-microglobulin (β2M)
    -/-
    triple-knockout (T-KO) male mice with full fertility. T-KO sperm exhibited an increased sperm number in the perivitelline space of wild-type (WT) eggs in vitro. Moreover, T-KO sperm showed multiple fusion with zona pellucida (ZP)-free WT eggs, implying that the ability of polyspermy block for sperm from T-KO males was weakened in WT eggs. When T-KO male mice were intercrossed with WT female mice, the percentage of females in progeny increased. We speculate that WT eggs prefer fusion with T-KO sperm, more specifically X-chromosome-bearing sperm (X sperm), suggesting the presence of preferential (non-random) fertilization in mammals, including humans.

    DOI： 10.3390/ijms21228731

  • Correction: Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction. International journal

    Woojin Kang, Yuichirou Harada, Kenji Yamatoya, Natsuko Kawano, Seiya Kanai, Yoshitaka Miyamoto, Akihiro Nakamura, Mami Miyado, Yoshiki Hayashi, Yoko Kuroki, Hidekazu Saito, Yasuhiro Iwao, Akihiro Umezawa, Kenji Miyado

    Laboratory investigation; a journal of technical methods and pathology   100 ( 4 )   665 - 665   2020.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/s41374-019-0369-8

  • The regulation of Drosophila ovarian stem cell niches by signaling crosstalk Reviewed International journal

    Hayashi, Yoshiki, Yoshinari, Yuto, Kobayashi, Satoru, Niwa, Ryusuke

    Current opinion in insect science   37   23 - 29   2020.1

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    The regulation of Drosophila ovarian stem cell niches by signaling crosstalk
    The Drosophila female ovary is an excellent model for investigating how multiple stem cell types are coordinately regulated in vivo. The ovary contains at least two stem cell types, germline stem cells (GSCs) and somatic follicular stem cells (FSCs). Although GSCs and FSCs are maintained within a distinct extra-cellular microenvironment, known as a niche, they share some common signaling molecules to generate their own niche. To properly maintain these stem cell types, understanding how signaling molecules are regulated is essential. In this review, we summarize the recent understanding of the mechanisms maintaining GSCs and FSCs from the perspective of growth factor regulation and discuss how these regulatory mechanisms contribute to stem cell maintenance, competition, and survival.

    DOI： 10.1016/j.cois.2019.10.006

  • Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction Reviewed International journal

    Kang, Woojin, Harada, Yuichirou, Yamatoya, Kenji, Kawano, Natsuko, Kanai, Seiya, Miyamoto, Yoshitaka, Nakamura, Akihiro, Miyado, Mami, Hayashi, Yoshiki, Kuroki, Yoko, Saito, Hidekazu, Iwao, Yasuhiro, Umezawa, Akihiro, Miyado, Kenji

    Laboratory investigation; a journal of technical methods and pathology   100 ( 4 )   583 - 595   2019.12

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    Language：English   Publishing type：Research paper (scientific journal)  

    Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction
    Men and women become infertile with age, but the mechanism of declining male fertility, more specifically, the decrease in in sperm quality, is not well known. Citrate synthase (CS) is a core enzyme of the mitochondrial tricarboxylic acid (TCA) cycle, which directly controls cellular function. Extra-mitochondrial CS (eCS) is produced and abundant in the sperm head; however, its role in male fertility is unknown. We investigated the role of eCS in male fertility by producing eCs-deficient (eCs-KO) mice. The initiation of the first spike of Ca oscillation was substantially delayed in egg fused with eCs-KO sperm, despite normal expression of sperm factor phospholipase C zeta 1. The eCs-KO male mice were initially fertile, but the fertility dropped with age. Metabolomic analysis of aged sperm revealed that the loss of eCS enhances TCA cycle in the mitochondria with age, presumably leading to depletion of extra-mitochondrial citrate. The data suggest that eCS suppresses age-dependent male infertility, providing insights into the decline of male fertility with age.

    DOI： 10.1038/s41374-019-0353-3

  • Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis. Reviewed

    112 ( 5 )   1452 - 1457   2015.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    In Drosophila, pulsed production of the steroid hormone ecdysone plays a pivotal role in developmental transitions such as metamorphosis. Ecdysone production is regulated in the prothoracic gland (PG) by prothoracicotropic hormone (PTTH) and insulin-like peptides (Ilps). Here, we show that monoaminergic autocrine regulation of ecdysone biosynthesis in the PG is essential for metamorphosis. PG-specific knockdown of a monoamine G protein-coupled receptor, β3-octopamine receptor (Octβ3R), resulted in arrested metamorphosis due to lack of ecdysone. Knockdown of tyramine biosynthesis genes expressed in the PG caused similar defects in ecdysone production and metamorphosis. Moreover, PTTH and Ilps signaling were impaired by Octβ3R knockdown in the PG, and activation of these signaling pathways rescued the defect in metamorphosis. Thus, monoaminergic autocrine signaling in the PG regulates ecdysone biogenesis in a coordinated fashion on activation by PTTH and Ilps. We propose that monoaminergic autocrine signaling acts downstream of a body size checkpoint that allows metamorphosis to occur when nutrients are sufficiently abundant.

    DOI： 10.1073/pnas.1414966112

  • Analysis of Drosophila glucuronyl C5-epimerase: implications for developmental roles of heparan sulfate sulfation compensation and 2-O-sulfated glucuronic acid. Reviewed

    Katsufumi,Dejima, Masahiko,Takemura, Eriko,Nakato, Jesse,Peterson, Yoshiki,Hayashi, Akiko,Kinoshita-Toyoda, Hidenao,Toyoda, Hiroshi,Nakato

    J Biol Chem.   288 ( 48 )   34384 - 34393   2013.11

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    Analysis of Drosophila glucuronyl C5-epimerase: implications for developmental roles of heparan sulfate sulfation compensation and 2-O-sulfated glucuronic acid.
    During the biosynthesis of heparan sulfate (HS), glucuronyl C5-epimerase (Hsepi) catalyzes C5-epimerization of glucuronic acid (GlcA), converting it to iduronic acid (IdoA). Because HS 2-O-sulfotransferase (Hs2st) shows a strong substrate preference for IdoA over GlcA, C5-epimerization is required for normal HS sulfation. However, the physiological significance of C5-epimerization remains elusive. To understand the role of Hsepi in development, we isolated Drosophila Hsepi mutants. Homozygous mutants are viable and fertile with only minor morphological defects, including the formation of an ectopic crossvein in the wing, but they have a short lifespan.Wepropose that two mechanisms contribute to the mild phenotypes of Hsepi mutants: HS sulfation compensation and possible developmental roles of 2-O-sulfated GlcA (GlcA2S). HS disaccharide analysis showed that loss of Hsepi resulted in a significant impairment of 2-O-sulfation and induced compensatory increases in N- and 6-O-sulfation. Simultaneous block of Hsepi and HS 6-O-sulfotransferase (Hs6st) activity disrupted tracheoblast formation, a well established FGF-dependent process. This result suggests that the increase in 6-O-sulfation in Hsepi mutants is critical for the rescue of FGF signaling.We also found that the ectopic crossvein phenotype can be induced by expression of a mutant form of Hs2st with a strong substrate preference for GlcA-containing units, suggesting that thisphenotypeis associated with abnormal GlcA 2-O-sulfation. Finally, we show that Hsepi formed a complex with Hs2st and Hs6st in S2 cells, raising the possibility that this complex formation contributes to the close functional relationships between these enzymes. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

    DOI： 10.1074/jbc.M113.499269

  • Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen Reviewed

    Yoshiki Hayashi, Travis R. Sexton, Katsufumi Dejima, Dustin W. Perry, Masahiko Takemura, Satoru Kobayashi, Hiroshi Nakato, Douglas A. Harrison

    DEVELOPMENT   139 ( 22 )   4162 - 4171   2012.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1242/dev.078055

  • Expression of β-adrenergic-like octopamine receptors during Drosophila development. Reviewed

    29 ( 2 )   83 - 89   2012.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.2108/zsj.29.83

  • Drosophila Sex lethal Gene Initiates Female Development in Germline Progenitors Reviewed

    Kazuya Hashiyama, Yoshiki Hayashi, Satoru Kobayashi

    SCIENCE   333 ( 6044 )   885 - 888   2011.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1126/science.1208146

  • ショウジョウバエ生殖幹細胞システムにおける ニッチの場構築の分子機構

    林,良樹, 中藤博志, 小林 悟

    細胞工学   29 ( 7 )   645 - 651   2010.9

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation Reviewed

    Adam Kleinschmit, Takashi Koyama, Katsufumi Dejima, Yoshiki Hayashi, Keisuke Kamimura, Hiroshi Nakato

    DEVELOPMENTAL BIOLOGY   345 ( 2 )   204 - 214   2010.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.ydbio.2010.07.006

  • Drosophila glypicans regulate the germline stem cell niche Reviewed

    Yoshiki Hayashi, Satoru Kobayashi, Hiroshi Nakato

    JOURNAL OF CELL BIOLOGY   187 ( 4 )   473 - 480   2009.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1083/jcb.200904118

  • MAMO, a maternal BTB/POZ-Zn-finger protein enriched in germline progenitors is required for the production of functional eggs in Drosophila. Reviewed

    Masanori,Mukai, Yoshiki,Hayashi, Yu,Kitadate, Kayo,Arita, Satoru,Kobayashi

    Mech. Dev.   124 ( 7-8 )   570 - 583   2007.8

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    MAMO, a maternal BTB/POZ-Zn-finger protein enriched in germline progenitors is required for the production of functional eggs in Drosophila.
    A hallmark of germline cells throughout the animal kingdom is their ability to execute meiosis. However, despite its prime importance, little is known about how germline progenitors acquire this ability. In Drosophila, the primordial germ cells (PGCs) are characterized by the inheritance of germ plasm, which contains maternal factors that have sufficient ability to direct germline development. Here, we show that a novel maternal factor, MAMO, is autonomously required in PGCs to produce functional gametes. MAMO protein which contains both a BTB/POZ ((B) under bar road Complex, (T) under bar ramtrack, (B) under bar rie-a-brac/(P) under bar ox virus and (Z) under bar inc finger) domain and C2H2 zinc finger motifs is enriched in PGCs during embryogenesis. The PGCs with reduced maternal MAMO activity are able to undergo oogenesis, but fail to execute meiosis properly. In the resulting oocytes, meiosis-specific chromosomal configurations are impaired. We additionally show that the decondensation of fertilized sperm nuclei is also affected in the eggs. We propose that maternal MAMO activates downstream genes to promote specialized morphological changes of both female meiotic chromosomes and the sperm nucleus, which are critical in zygote formation. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

    DOI： 10.1016/j.mod.2007.05.001

  • Soma-dependent modulations contribute to divergence of rhomboid expression during evolution of Drosophila eggshell morphology Reviewed

    Yukio Nakamura, Tatsuo Kagesawa, Minori Nishikawa, Yoshiki Hayashi, Satoru Kobayashi, Teruyuki Niimi, Kenji Matsuno

    DEVELOPMENT   134 ( 8 )   1529 - 1537   2007.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1242/dev.001578

  • Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos Reviewed

    Yoshiki,Hayashi, Kimhiro,Sato, Yuichi,Ninomiya, Shuji,Shigenobu, Kayo,Arita, Masanori,Mukai, Satoru,Kobayashi

    Proc Natl Acad Sci U S A.   104 ( 18 )   7455 - 7460   2007.4

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    Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos

  • The role of mitochondrial rRNAs and nanos protein in germline formation in Drosophila embryos

    Satoru,Kobayashi, Kimihiro,Sato, Yoshiki,Hayashi

    Zoolog Sci.   22 ( 9 )   943 - 54   2005.9

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    The role of mitochondrial rRNAs and nanos protein in germline formation in Drosophila embryos
    Germ cells, represented by male sperm and female eggs, are specialized cells that transmit genetic material from one generation to the next during sexual reproduction. The mechanism by which multicellular organisms achieve the proper separation of germ cells and somatic cells is one of the longest standing issues in developmental biology. In many animal groups, a specialized portion of the egg cytoplasm, or germ plasm, is inherited by the cell lineage that gives rise to the germ cells (germline). Germ plasm contains maternal factors that are sufficient for germline formation. In the fruit fly, Drosophila, germ plasm is referred to as polar plasm and is distinguished histologically by the presence of polar granules, which act as a repository for the maternal factors required for germline formation. Molecular screens have so far identified several of these factors that are enriched in the polar plasm. This article focuses on the molecular functions of two such factors in Drosophila, mitochondrial ribosomal RNAs and Nanos protein, which are required for the formation and differentiation of the germline progenitors, respectively.

  • ショウジョウバエ極細胞の発生運命の制御機構

    林,良樹, 小林 悟

    蛋白質・核酸・酵素   2005.5

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Nanos suppresses somatic cell fate in Drosophila germ line Reviewed

    Y Hayashi, M Hayashi, S Kobayashi

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   101 ( 28 )   10338 - 10342   2004.7

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1073/pnas.040147101

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Books

  • Reproductive & Developmental Strategies for Life Continuity

    Yoshiki, Hayashi, Satoru, Kobayashi

    Springer Verlag  2018.6 

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    Reproductive & Developmental Strategies for Life Continuity

Presentations

  • ショウジョウバエ生殖系列の代謝的特徴とその役割 Invited

    @林良樹、@木村遼、@影山りお、@小林悟

    第46回日本分子生物学会年会  2023.12 

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    Event date： 2023.12

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：神戸ポートピアホテル（兵庫）   Country：Japan  

  • Overactivation of FGF signaling transforms chick primordial germ cells into soma in dorsal mesenteric environment

    #Iikawa. H., #Kishita, R., @Hayashi, Y., @Saito, D

    2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Country：Japan  

  • ショウジョウバエ生殖系列の代謝的特徴とその役割 Invited

    @林良樹、@木村遼、@影山りお、@小林悟

    第96回日本生化学会大会  2023.11 

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    Event date： 2023.11

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡国際会議場（福岡）   Country：Japan  

  • ニワトリ始原生殖細胞の発生における細胞内代謝の役割

    #西名藍花、@林良樹、@齋藤大介

    第96回日本生化学会大会  2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Venue：福岡国際会議場（福岡）   Country：Japan  

  • ニワトリPGCの初期発生過程におけるNotchシグナルの機能解析

    #龍野あすか、@林良樹、@齋藤大介

    第96回日本生化学会大会  2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Venue：福岡国際会議場（福岡）   Country：Japan  

  • ショウジョウバエ生殖系列の発生過程におけるヒストンラクチル化修飾の観察

    @林良樹, @影山りお

    第16回日本エピジェネティクス研究会年会  2023.6 

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    Event date： 2023.6

    Language：Japanese  

    Venue：学術総合センター一橋講堂（東京）   Country：Japan  

  • S-adenosylmethionine and its biosynthetic pathway in the corpus allatum are involved in juvenile hormone biosynthesis in Drosophila melanogaster

    Mizuno, Yosuke, Kurogi, Yoshitomo, Yoshinari, Yuto, Imura, Eisuke, Hoshino, Ryo, Hayashi, Yoshiki, Obata, Fumiaki, Niwa, Ryusuke

    The 6th International Insect Hormone Workshop 

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    Event date： 2023.6

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    S-adenosylmethionine and its biosynthetic pathway in the corpus allatum are involved in juvenile hormone biosynthesis in Drosophila melanogaster

  • 解糖系によるショウジョウバエ生殖系列の発生制御 Invited

    林, 良樹

    第45回日本分子生物学会年会 

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    Event date： 2022.11 - 2022.12

    Language：Others  

    Venue：幕張メッセ（千葉）   Country：Other  

  • ショウジョウバエ生殖系列の発生過程におけるヒストンラクチル化修飾の観察

    林, 良樹

    第45回日本分子生物学会年会 

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    Event date： 2022.11 - 2022.12

    Language：Others  

    Venue：幕張メッセ（千葉）   Country：Other  

  • ショウジョウバエ始原生殖細胞における解糖系によるヒストンアセチル化制御とクロマチン構造への影響評価に向けて

    林, 良樹

    第45回日本分子生物学会年会 

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    Event date： 2022.11 - 2022.12

    Language：Others  

    Venue：幕張メッセ（千葉）   Country：Other  

  • Investigating the importance of the methionine cycle for juvenile hormone biosynthesis in the fruit fly Drosophila melanogaster

    Mizuno, Yosuke, Kurogi, Yoshitomo, Yoshinari, Yuto, Imura, Eisuke, Hoshino, Ryo, Hayashi, Yoshiki, Niwa, Ryusuke

    15th Japan Drosophila Research Conference  2022.9 

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    Event date： 2022.9

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    Investigating the importance of the methionine cycle for juvenile hormone biosynthesis in the fruit fly Drosophila melanogaster

  • Glycolysis regulates primordial germ cell development of Drosophila

    2022.6 

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    Event date： 2022.6

    Language：Japanese  

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    Glycolysis regulates primordial germ cell development of Drosophila

  • Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis

    2022.6 

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    Event date： 2022.6

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    Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis

  • Glycolysis regulates Histone Acetylation during Primordial Germ Cell Development of Drosophila.

    2021.12 

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    Event date： 2021.12

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    Glycolysis regulates Histone Acetylation during Primordial Germ Cell Development of Drosophila.

  • Glycolysis regulates primordial germ cell development of Drosophila

    2021.12 

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    Event date： 2021.12

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    Glycolysis regulates primordial germ cell development of Drosophila

  • Glycolysis regulates primordial germ cell development of Drosophila-

    2021.12 

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    Event date： 2021.12

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    Glycolysis regulates primordial germ cell development of Drosophila-

  • ショウジョウバエ始原生殖細胞の発生過程における解糖系の役割

    林,良樹

    第94回日本生化学会大会  2021.11 

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    Event date： 2021.11

    Language：Japanese  

    Venue：オンライン（zoom）   Country：Other  

  • Glycolysis inhibits primordial germ-cell development of Drosophila melanogaster

    Hayashi,Yoshiki

    2021.9 

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    Event date： 2021.9

    Language：English  

    Country：Other  

    Glycolysis inhibits primordial germ-cell development of Drosophila melanogaster

  • Glycolysis inhibits primordial germ-cell development of Drosophila melanogaster

    2021.6 

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    Event date： 2021.6

    Language：Japanese  

    Country：Other  

    Glycolysis inhibits primordial germ-cell development of Drosophila melanogaster

  • 生体組織内 液-液相分離のラベルフリー非線形光学イメージング

    林,良樹

    第6回超高速エレクトロニクス（UFO)研究会  2021.2 

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    Event date： 2021.2

    Language：Japanese  

    Venue：オンライン   Country：Other  

  • ショウジョウバエ生殖系列の発生過程における細胞内代謝の役割

    林,良樹

    第7回メタボローム勉強会  2020.2 

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    Event date： 2020.2

    Language：Japanese  

    Venue：慶應義塾大学先端生命科学研究所 鶴岡   Country：Other  

  • メタボロミクスから見えてきたショウジョウバエ生殖系列の代謝的特徴とその役割 Invited

    林,良樹

    九州大学理学研究院・生物科学部門セミナー  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Country：Other  

  • メチオニン代謝制御による生殖系列におけるレトロトランスポゾンの抑制

    林,良樹

    第４２回日本分子生物学会年会 ーフェイトメタボライツ：細胞運命を決定する代謝物質群ー  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ生殖系列におけるメチオニン代謝制御によるレトロトランスポゾン抑制の仕組み

    林, 良樹, 日野信次朗, 樫尾宗志朗, 斎藤都暁, 三浦正幸, 中尾光善, 小林, 悟

    第４２回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Country：Other  

  • 始原生殖細胞の発生過程における細胞内代謝の役割

    林,良樹

    第３回がんと代謝研究会・若手の会  2019.11 

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    Event date： 2019.11

    Language：Japanese  

    Venue：熊本大学発生医学研究所   Country：Other  

  • メタボロミクスから見えてきたショウジョウバエ 生殖系列の代謝的性質とその役割

    林,良樹

    第１３回 メタボロームシンポジウム  2019.10 

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    Event date： 2019.10

    Language：Japanese  

    Venue：筑波大学大学会館 つくば   Country：Other  

  • The role of heparan sulfate proteoglycans in Drosophila germline stem cell niche.

    Hayashi,Yoshiki

    Proteoglycans 2019. New frontiers in the biology of proteoglycan research.  2019.9 

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    Event date： 2019.9 - 2019.10

    Language：English  

    Country：Other  

    The role of heparan sulfate proteoglycans in Drosophila germline stem cell niche.

  • メタボロミクスからみえてきたショウジョウバエ生殖系列の 代謝的性質とその役割 Invited

    林,良樹

    首都大学東京・教室セミナー  2019.9 

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    Event date： 2019.9

    Language：Japanese  

    Country：Other  

  • メチオニン代謝制御による生殖系列におけるトランスポゾン抑制機構

    林, 良樹, 小林, 悟

    第90回日本動物学会大会  2019.9 

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    Event date： 2019.9

    Language：Japanese  

    Country：Other  

  • Characteristics of Drosophila germ-line from metabolic aspects.

    Hayashi,Yoshiki

    TARA International Symposium, Satellite Meeting  2019.3 

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    Event date： 2019.3

    Language：English  

    Country：Other  

    Characteristics of Drosophila germ-line from metabolic aspects.

  • Methionine metabolism regulates retrotransposon expression in germline of Drosophila melanogaster.

    2018.11 

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    Event date： 2018.11

    Language：Japanese  

    Country：Other  

    Methionine metabolism regulates retrotransposon expression in germline of Drosophila melanogaster.

  • 生殖系列の代謝とその役割ーメチオニン代謝制御によるトランスポソンの発現抑制

    林,良樹

    日本発生生物学会秋季シンポジウム2018 ー次の１０年間の発生生物学の潮流を考えるー  2018.11 

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    Event date： 2018.11

    Language：Japanese  

    Country：Other  

  • Methionine metabolism regulates retrotransposon expression in germline of Drosophila melanogaster

    Hayashi, Yoshiki, Hino, Shinjiro, Sato, Tetsuya, Kashio, Soshiro, Noda, Chiyo, Miura, Masayuki, Nakao, Mitsuyoshi, Kobayashi, Satoru

    2018.11 

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    Event date： 2018.11

    Language：English  

    Country：Other  

    Methionine metabolism regulates retrotransposon expression in germline of Drosophila melanogaster

  • Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster. International conference

    Hayashi,Yoshiki

    Cold Spring Harbor Laboratory meeting on Germ Cells, 2018  2018.10 

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    Event date： 2018.10

    Language：English  

    Country：Other  

    Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster.

  • Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster International conference

    Hayashi, Yoshiki, Hino, Shinjiro, Kashio, Soshiro, Sato, Tetsuya, Noda, Chiyo, Miura, Masayuki, Nakao, Mitsuyoshi, Kobayashi, Satoru

    Cold Spring Harbor Laboratory Meeting  2018.10 

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    Event date： 2018.10

    Language：English  

    Country：Other  

    Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster

  • Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster.

    Hayashi,Yoshiki

    51st Annual Meeting of Japanese Society of Developmental Biologists  2018.6 

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    Event date： 2018.6

    Language：English  

    Country：Other  

    Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster.

  • Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster

    Hayashi, Yoshiki, Hino, Shinjiro, Kashio, Soshiro, Sato, Tetsuya, Noda, Chiyo, Miura, Masayuki, Nakao, Mitsuyoshi, Kobayashi, Satoru

    2018.6 

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    Event date： 2018.6

    Language：English  

    Country：Other  

    Role of Methionine Metabolism during Germ-line Development of Drosophila melanogaster

  • Characteristics of Drosophila Germ-line from Metabolic Aspects.-The role of methionine metabolism during germ-line development of Drosophila – Invited

    2018.3 

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    Event date： 2018.3

    Language：English  

    Country：Other  

  • メタボロミクスから見えてきたショウジョウバエ始原生殖細胞の代謝的性質とその役割 ～メチオニン代謝制御によるとランスポソン抑制の仕組み～ Invited

    第６回 生殖若手の会  2018.2 

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    Event date： 2018.2 - 2018.3

    Language：Japanese  

    Country：Other  

  • メタボロミクスから見えてきたショウジョウバエ始原生殖細胞の代謝的性質とその役割 ～メチオニン代謝制御によるとランスポソン抑制の仕組み～ Invited

    第５回 植物発生ロジック・メタボロミクス勉強会  2018.2 

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    Event date： 2018.2

    Language：Japanese  

    Country：Other  

  • The role of methionine metabolism during germ-line development of Drosophila melanogaster.

    Hayashi,Yoshiki

    KEY Forum: The 3rd International Symposium on Stem Cell Traits and Developmental Systems.  2018.1 

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    Event date： 2018.1

    Language：English  

    Country：Other  

    The role of methionine metabolism during germ-line development of Drosophila melanogaster.

  • メチオニン代謝制御による生殖系列におけるトランスポゾン抑制機構

    日本動物学会 第８８回 富山大会２０１７  2017.9 

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    Event date： 2017.9

    Language：Japanese  

    Venue：富山県民会館（富山）   Country：Other  

  • The role of methionine metabolism during germ-line development of Drosophila melanogaster.

    Hayashi,Yoshiki

    The international research symposium on regulation of germ cell development in vivo and in vitro.  2017.7 

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    Event date： 2017.7

    Language：English  

    Country：Other  

    The role of methionine metabolism during germ-line development of Drosophila melanogaster.

  • The role of methionine metabolism during germline development in Drosophila melanogaster

    Yoshiki, Hayashi, Chiyo, Noda, Kobayashi, Satoru

    The International Research Symposium on Regulation of Germ Cell Development in vivo and in vitro  2017.7 

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    Event date： 2017.7

    Language：English  

    Country：Other  

    The role of methionine metabolism during germline development in Drosophila melanogaster

  • メタボロミクスから見えてきたショウジョウバエ始原生殖細胞の代謝的性質とその役割 Invited

    東北大学農学研究科セミナー  2017.6 

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    Event date： 2017.6

    Language：Japanese  

    Country：Other  

  • The role of methionine metabolism during germline development in Drosophila melanogaster.

    Hayashi,Yoshiki

    50th annual meeting of Japanese Society of Developmental Biologists.  2017.5 

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    Event date： 2017.5

    Language：English  

    Country：Other  

    The role of methionine metabolism during germline development in Drosophila melanogaster.

  • The role of methionine metabolism during germline development in Drosophila melanogaster

    Hayashi, Yoshiki, Noda, Chiyo, Kobayashi, Satoru

    2017.5 

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    Event date： 2017.5

    Language：English  

    Country：Other  

    The role of methionine metabolism during germline development in Drosophila melanogaster

  • The role of methionine metabolism during germline development in Drosophila melanogaster.

    Hayashi,Yoshiki

    The joint meeting of the 22nd International Congress of Zoology and the 87th Meeting of the Zoological Society of Japan  2016.11 

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    Event date： 2016.11

    Language：English  

    Country：Other  

    The role of methionine metabolism during germline development in Drosophila melanogaster.

  • ショウジョウバエ始原生殖細胞の代謝的性質とその役割-生殖系列の品質管理におけるメチオニン代謝の役割ー Invited

    第３９回日本分子生物学会年会  2016.11 

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    Event date： 2016.11 - 2016.12

    Language：Japanese  

    Venue：神奈川   Country：Other  

  • メタボロミクスから見えてきた始原生殖細胞の代謝的性質とその役割 Invited

    林,良樹, 野田千代, 小林悟

    第１４回日本再生医療学会総会  2015.3 

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    Event date： 2015.3

    Language：Japanese  

    Country：Other  

  • The role of Glycolysis in primordial germ cell development of Fruit fly, Drosophila melanogaster Invited

    Hayashi,Yoshiki

    2014.12 

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    Event date： 2014.12

    Language：English  

    Country：Other  

    The role of Glycolysis in primordial germ cell development of Fruit fly, Drosophila melanogaster

  • メタボロミクスから見えてきた始原生殖細胞の代謝的性質とその役割 Invited

    林,良樹, 野田千代, 小林悟

    第８７回日本生化学会大会  2014.10 

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    Event date： 2014.10

    Language：Japanese  

    Country：Other  

  • Role of Glycolysis in Primordial-Germ-Cell Development in Drosophila embryos. International conference

    Hayashi,Yoshiki, Noda,Chiyo, Kobayashi,Satoru

    Cold Spring Horbor Laboratory meeting on Germ Cell  2014.10 

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    Event date： 2014.10

    Language：English  

    Country：Other  

    Role of Glycolysis in Primordial-Germ-Cell Development in Drosophila embryos.

  • ショウジョウバエ始原生殖細胞におけるメチオニン代謝状態とその発生過程における役割

    林,良樹, 野田千代, 小林悟

    第８５回日本動物学会大会  2014.9 

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    Event date： 2014.9

    Language：Japanese  

    Country：Other  

  • The role of Heparan Sulfate Proteoglycans in Drosophila germline stem cell niche. Invited

    Hayashi,Yoshiki, Sugiyama,Arisa, Kobayashi,Satoru

    2014.5 

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    Event date： 2014.5

    Language：English  

    Country：Other  

    The role of Heparan Sulfate Proteoglycans in Drosophila germline stem cell niche.

  • ショウジョウバエ始原生殖細胞の発生過程における解糖系の新規役割

    林,良樹

    日本発生生物学会 秋季シンポジウム２０１３  2013.11 

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    Event date： 2013.11

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程における解糖系の役割 Invited

    林,良樹

    第１回がんと代謝研究会  2013.10 

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    Event date： 2013.10 - 2013.11

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程における解糖系の新規役割

    林,良樹, 野田 千代, 小林悟

    第８４回日本動物学会大会  2013.9 

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    Event date： 2013.9

    Language：Japanese  

    Country：Other  

  • Role of Glycolysis in Primordial-Germ-Cell Development in Drosophila embryos

    Hayashi,Yoshiki, Noda,Chiyo, Kobayashi,Satoru

    2013.5 

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    Event date： 2013.5

    Language：English  

    Country：Other  

    Role of Glycolysis in Primordial-Germ-Cell Development in Drosophila embryos

  • "ショウジョウバエ配偶子形成過程におけるヘパラン硫酸プロテオグリカン の役割" Invited

    林,良樹, 中藤博志, 小林悟

    第８５回日本生化学会大会  2012.12 

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    Event date： 2012.12

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程における細胞内代謝の新規役割

    林,良樹, 野田千代, 小林悟

    第３５回日本分子生物学会年会  2012.12 

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    Event date： 2012.12

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程におけるエネルギー代謝の新規役割 Invited

    林,良樹

    第６４回日本発生工学会  2012.10 

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    Event date： 2012.10

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程における細胞内代謝の新規役割

    林,良樹, 野田千代, 小林悟

    第８３回日本動物学会大会  2012.9 

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    Event date： 2012.9

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始原生殖細胞の発生過程における細胞内代謝の新規役割

    林,良樹, 野田千代, 小林悟

    日本発生生物学会 秋季シンポジウム２０１１  2011.12 

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    Event date： 2011.12

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ始源生殖細胞における代謝状態の解析

    林,良樹, 野田千代, 小林悟

    第８２回日本動物学会大会  2011.9 

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    Event date： 2011.9

    Language：Japanese  

    Country：Other  

  • The role of heparan sulfate proteoglycans during Drosophila gametogenesisn

    Hayashi,Yoshiki, Kobayashi,Satoru, Nakato,Hiroshi

    2011.5 

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    Event date： 2011.5

    Language：English  

    Country：Other  

    The role of heparan sulfate proteoglycans during Drosophila gametogenesisn

  • The role of Heparan Sulfate Proteoglycans in Drosophila germline stem cell niche.

    Hayashi,Yoshiki, Kobayashi,Satoru, Nakato,Hiroshi

    the 16th international conference of the international society of differentiation  2010.11 

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    Event date： 2010.11

    Language：English  

    Country：Other  

    The role of Heparan Sulfate Proteoglycans in Drosophila germline stem cell niche.

  • An Essential Role of Heparan Sulfate Proteoglycans in Drosophila International conference

    Hayashi,Yoshiki, Nakato,Hiroshi, Kobayashi,Satoru

    Cold Spring Horbor Laboratory meeting on Germ Cell 2010  2010.10 

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    Event date： 2010.10

    Language：English  

    Country：Other  

    An Essential Role of Heparan Sulfate Proteoglycans in Drosophila

  • ショウジョウバエ生殖幹細胞ニッチの場におけるヘパラン硫酸プロテオグリカンの役割

    林,良樹, 小林悟, 中藤博志

    第８１回日本動物学会大会  2010.9 

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    Event date： 2010.9

    Language：Japanese  

    Country：Other  

  • An Essential Role of Heparan Sulfate Proteoglycans in Drosophila

    Hayashi,Yoshiki, Kobayashi,Satoru, Nakato,Hiroshi

    the 28th Naito Conference  2010.7 

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    Event date： 2010.7

    Language：English  

    Country：Other  

    An Essential Role of Heparan Sulfate Proteoglycans in Drosophila

  • ショウジョウバエ生殖幹細胞ニッチにおける ヘパラン硫酸プロテオグリカンの役割

    林,良樹, 津田弥生, 小林悟, 中藤博志

    第３２回日本分子生物学会  2009.12 

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    Event date： 2009.12

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ生殖幹細胞ニッチにおける ヘパラン硫酸プロテオグリカンの役割

    林,良樹, 津田弥生, 小林悟, 中藤博志

    第８０回日本動物学会大会  2009.9 

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    Event date： 2009.9

    Language：Japanese  

    Country：Other  

  • The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche

    Hayashi,Yoshiki, Tsuda,Yayoi, Kobayashi,Satoru, Nakato,Hiroshi

    2009.5 

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    Event date： 2009.5

    Language：English  

    Country：Other  

    The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche

  • The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche

    2008.12 

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    Event date： 2008.12

    Language：Japanese  

    Country：Other  

    The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche

  • The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche International conference

    Hayashi,Yoshiki, Tsuda,Yayoi, Kobayashi,Satoru, Nakato,Hiroshi

    Cold Spring Horbor Laboratory meeting on Germ Cell 2008  2008.10 

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    Event date： 2008.10

    Language：English  

    Country：Other  

    The Role of Heparan Sulfate Proteoglycan in Drosophila Germline Stem Cell Niche

  • ショウジョウバエ生殖幹細胞ニッチにおけるヘパラン硫酸プロテオグリカンの役割 Invited

    林,良樹

    第１６回プロテオグリカンフォーラム  2008.9 

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    Event date： 2008.9

    Language：Japanese  

    Country：Other  

  • ショウジョウバエ生殖幹細胞ニッチにおける ヘパラン硫酸プロテオグリカンの役割

    林,良樹, 津田弥生, 小林悟, 中藤博志

    第７９回日本動物学会大会  2008.9 

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    Event date： 2008.9

    Language：Japanese  

    Country：Other  

  • The Role of Heparan Sulfate Proteoglycans in Drosophila Germ Line Stem Cell Niche International conference

    Hayashi,Yoshiki, Tsuda,Yayoi, Hiroshi,Nakato

    Gordon Research Conference on Proteoglyans  2008.7 

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    Event date： 2008.7

    Language：English  

    Country：Other  

    The Role of Heparan Sulfate Proteoglycans in Drosophila Germ Line Stem Cell Niche

  • The role of heparan sulfate proteoglycans during Drosophila gametogenesis International conference

    Hayashi,Yoshiki, Tsuda,Yayoi, Nakato,Hiroshi

    2007.9 

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    Event date： 2007.9

    Language：English  

    Country：Other  

    The role of heparan sulfate proteoglycans during Drosophila gametogenesis

  • ショウジョウバエ生殖系列におけるメチオニン代謝制御によるレトロトランスポゾン抑制の仕組み

    林, 良樹, 日野信次朗, 樫尾宗志朗, 佐藤哲也, 野田千代, 三浦正幸, 中尾光善, 小林, 悟

    第89回日本動物学会大会  2018.9 

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    Language：Japanese  

    Country：Other  

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Industrial property rights

Patent   Number of applications: 1   Number of registrations: 0
Utility model   Number of applications: 0   Number of registrations: 0
Design   Number of applications: 0   Number of registrations: 0
Trademark   Number of applications: 0   Number of registrations: 0

Professional Memberships

  • 日本分子生物学会

  • 日本発生生物学会

  • 日本動物学会

  • 日本生化学会

  • 日本エピジェネティクス研究会

  • THE JAPANESE BIOCHEMICAL SOCIETY

  • The Molecular Biology Society of Japan

  • Japanese Society of Developmental Biologists

  • THE ZOOLOGICAL SOCIETY OF JAPAN

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Committee Memberships

  • Executive   Domestic

    2017.1 - 2023.6   

  • 日本発生生物学会   キャリア支援担当   Domestic

    2017.1 - 2023.6   

Academic Activities

  • シンポジウムオーガナイザー

    第96回日本生化学会大会  （ 福岡国際会議場 ） 2023.10 - 2023.11

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    Type：Competition, symposium, etc. 

  • Screening of academic papers

    Role(s)： Peer review

    2023

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    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：3

  • 文部科学省・科学技術・学術政策研究所・科学技術動向研究センター　専門調査委員

    Role(s)： Review, evaluation

    文部科学省・科学技術・学術政策研究所・科学技術動向研究センター  2015.4 - 2020.3

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    Type：Scientific advice/Review 

  • 生化学

    2014.4 - 2019.12

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    Type：Academic society, research group, etc. 

Other

  • 文部科学省 科学技術...

    2015.4

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    文部科学省 科学技術・学術政策研究所 科学技術動向研究センター 専門調査委員

  • 文部科学省 科学技術・学術政策研究所 科学技術動向研究センター 専門調査委員

    2015.4

  • 「生化学」誌 企画協...

    2014.4

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    「生化学」誌 企画協力委員

  • 「生化学」誌 企画協力委員

    2014.4

Research Projects

  • 抗老化創薬を目指した組織老化におけるS-アデノシルメチオニンの役割の解明

    2019

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • TIA連携プログラム「かけはし」/抗老化創薬を目指した組織老化におけるS-アデノシルメチオニンの役割の解明

    2019

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    Grant type：Donation

  • 生殖系列のメチオニン代謝制御によるレトロトランスポゾンの抑制機構の解明

    Grant number：18K06240  2018 - 2022

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type：Scientific research funding

  • ショウジョウバエ始原生殖細胞の転写抑制機構におけるメチオニン代謝の役割 Publicly

    Grant number：26116730  2014 - 2016

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • ショウジョウバエ始原生殖細胞におけるミトコンドリア品質管理機構の解析

    Grant number：25711020  2013 - 2017

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • ショウジョウバエ始原生殖細胞の遺伝子発現制御における細胞内代謝経路の役割

    Grant number：24116527  2012 - 2014

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 内藤記念特定研究助成/生殖幹細胞ニッチにおけるHSPGの役割

    2010

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    Grant type：Donation

  • ショウジョウバエ生殖幹細胞の「ニッチの場」形成の分子メカニズムの解析

    Grant number：21770253  2008 - 2012

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • ショウジョウバエ卵巣/精巣におけるGSC/ニッチ・システムの解明

    Grant number：20116002  2008 - 2012

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type：Scientific research funding

▼display all

Class subject

  • 生物科学I

    2024.4 - 2024.9   First semester

  • 生命の科学A

    2024.4 - 2024.9   First semester

  • 生物学演習

    2023.10 - 2023.12   Fall quarter

  • 自然科学総合実験

    2023.10 - 2023.12   Fall quarter

  • 発生生物学

    2023.10 - 2023.12   Fall quarter

Activities contributing to policy formation, academic promotion, etc.

  • 2021.6   日本発生生物学会

    日本発生生物学会第54回大会におけるキャリア支援ランチョンセミナー”イノベーションの再生に向けてー「知」を「価値」に変えるー”の開催

  • 2019.6   日本発生生物学会

    日本発生生物学会第52回大会におけるキャリア支援ランチョンセミナー”翔け博士人材”の開催

  • 2018.6   日本発生生物学会

    日本発生生物学会第51回大会におけるキャリア支援ランチョンセミナー”JREC-IN Portalの紹介　一度は見たことあるけど、どう使うの？”の開催

  • 2016.7 - 2017.6   日本発生生物学会・国立科学博物館

    国立科学博物館企画展”卵からはじまる形づくりー発生生物学への誘いー”制作委員