Updated on 2024/10/13

Information

 

写真a

 
YOSHIDA HIROSHI
 
Organization
Faculty of Mathematics Division of Analysis Associate Professor
School of Sciences Department of Mathematics(Concurrent)
Graduate School of Mathematics Department of Mathematics(Concurrent)
Joint Graduate School of Mathematics for Innovation (Concurrent)
Graduate School of Systems Life Sciences Department of Systems Life Sciences(Concurrent)
Title
Associate Professor
External link

Degree

  • Ph. D.

Research Interests・Research Keywords

  • Research theme: A pattern to regenerate through turnover

    Keyword: turnover, regenerative field

    Research period: 2010.1 - 2022.3

Papers

  • A model for analyzing phenomena in multicellular organisms with multivariable polynomials: Polynomial Life Reviewed International journal

    Hiroshi Yoshida

    Int. J. Biomath.   11 ( 1 )   1850007   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

  • An extended steepness model for leg-size determination based on Dachsous/Fat trans-dimer system Reviewed International journal

    Hiroshi Yoshida, Tetsuya Bando, Taro Mito, Hideyo Ohuchi, Sumihare Noji

    Scientific Reports   4   4335   2014.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    What determines organ size has been a long-standing biological question. Lawrence et al. (2008) proposed the steepness hypothesis suggesting that the protocadherin Dachsous/Fat (Ds/Ft) system may provide some measure of dimension to the cells in relation to the gradient. In this paper we extended the model as a means of interpreting experimental results in cricket leg regeneration. We assumed that (1) Ds/Ft trans-heterodimers or trans-homodimers are redistributed during cell division, and (2) growth would cease when a differential of the dimer across each cell decreases to a certain threshold. We applied our model to simulate the results obtained by leg regeneration experiments in a cricket model. The results were qualitatively consistent with the experimental data obtained for cricket legs by RNA interference methodology. Using our extended steepness model, we provided a molecular-based explanation for leg size determination even in intercalary regeneration and for organ size determination.

    DOI: 10.1038/srep04335

    Other Link: http://dx.doi.org/10.1038/srep04335

  • A pattern to regenerate through turnover International journal

    Hiroshi Yoshida

    Biosystems   110   2012.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.biosystems.2012.08.001

    Other Link: http://dx.doi.org/10.1016/j.biosystems.2012.08.001

  • Elliptic curves and Fibonacci numbers arising from Lindenmayer system with Symbolic Computation Reviewed International journal

    Hiroshi Yoshida, Yoshihiro Miwa, Masanobu KANEKO

    Applicable Algebra in Engineering, Communication and Computing   22 ( 2 )   2011.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00200-011-0143-7

    Other Link: http://dx.doi.org/10.1007/s00200-011-0143-7

  • An Integrated Topological-Lindenmayer System Model of Volvox Embryonic Inversion And Cell Division, Apoptosis and Cancer Growth Models Reviewed

    SARANYA DAS ROY and HIROSHI YOSHIDA

    8th International Conference on Computational Biology and Bioinformatics   2024.11

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    Authorship:Last author   Language:English   Publishing type:Research paper (international conference proceedings)  

  • A condition for regeneration of a cell chain inspired by the Dachsous-Fat system Reviewed

    Hiroshi Yoshida

    Journal of Math-for-Industry   3   2011.10

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books

  • 代数生物学

    吉田 寛(Role:Sole author)

    講談社サイエンティフィック  2008.6 

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    Responsible for pages:『大規模・高精度計算が拓いた新技法』 若山 正人 (編集), pp. 62-117   Language:Japanese   Book type:Scholarly book

Presentations

  • A model of regenerating patterns using a random-walk model International conference

    Hiroshi Yoshida

    Moscow Conference on Computational Molecular Biology  2019.7 

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    Event date: 2019.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:モスクワ   Country:Russian Federation  

  • A model of regenerating pattern using multivariable polynomials ーーPolynomial Lifeーー International conference

    Hiroshi Yoshida

    International Conference on Bioinformatics and Systems Biology  2018.10 

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    Event date: 2018.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:アラハバード   Country:India  

  • A model for analyzing phenomena in multicellular organisms with multivariable polynomials International conference

    吉田 寛

    EMBO Conference: From Functional Genomics to Systems Biology  2016.11 

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    Event date: 2016.11

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:ハイデルベルグ   Country:Germany  

  • A model towards multicell-turnover patterns using multivariable polynomials - Polynomial Life International conference

    Hiroshi Yoshida

    Hybrid Systems Biology  2015.9 

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    Event date: 2015.9

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Madrid   Country:Spain  

  • A model of cell-division stop for the limb regeneration

    吉田寛

    第50回生物物理学会  2012.9 

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    Event date: 2012.9

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • リンデンマイアシステム上の多細胞モデルと限量記号消去法

    吉田 寛

    第10回論理と計算セミナー  2012.9 

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    Event date: 2012.9

    Presentation type:Oral presentation (general)  

    Venue:九州産業大   Country:Japan  

  • A model of cell-division stop for the limb regeneration International conference

    Hiroshi Yoshida, Tetsuya Bando, and Sumihare Noji

    BSCB/BSDB/JSDB Joint meeting  2012.4 

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    Event date: 2012.4

    Presentation type:Symposium, workshop panel (public)  

    Venue:Coventry, Univ. of Warwick   Country:United Kingdom  

  • A Model for Cell-division Stop and Re- generation based on Dachsous/Fat heterodimer system International conference

    Hiroshi Yoshida, Tetsuya Bando, and Sumihare Noji

    The 2nd international conference on the Cricket/RNAi Symposium  2012.3 

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    Event date: 2012.3

    Presentation type:Oral presentation (general)  

    Venue:徳島大学   Country:Japan  

  • Models of Cell-division Stoppage based on Dachsous/Fat heterodimer system International conference

    Hiroshi Yoshida, Tetsuya Bando, and Sumihare Noji

    The 21st CDB Meeting: from Regeneration Biology to Regenerative Medicine  2011.11 

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    Event date: 2011.11

    Presentation type:Symposium, workshop panel (public)  

    Venue:神戸   Country:Japan  

  • Regenerative equations of Dachsous=Fat heterodimeric system

    吉田 寛

    第49回生物物理学会  2011.9 

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    Event date: 2011.9

    Presentation type:Oral presentation (general)  

    Venue:姫路   Country:Japan  

  • A condition for regeneration of a cell chain based on Dachsous:Fat heterodimer system International conference

    H. Yoshida

    The European Conference on Mathematical and Theoretical Biology  2011.6 

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    Event date: 2011.6 - 2011.7

    Presentation type:Oral presentation (general)  

    Venue:Krakow   Country:Poland  

  • Analysis of multicell-turnover patterns with multivariable polynomial modeling International conference

    吉田 寛

    International Conference on Systems Biology 2014  2014.9 

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    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Melbourne   Country:Australia  

  • A model towards analysis of regenerating patterns using multivariable polynomials — Polynomial Life — International conference

    Hiroshi Yoshida

    21st International Symposium on Artificial Life and Robotics  2016.1 

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    Language:English   Presentation type:Oral presentation (general)  

    Venue:B-Con PLAZA, 別府   Country:Japan  

  • A model of cell-group regeneration with the aid of log-periodic curves International conference

    H. Yoshida

    AROB-ISBC-SWARM22  2022.1 

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    Event date: 2022.1

    Language:English   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  • A model for analyzing phenomena in multicellular organisms with multivariable polynomials: Polynomial-life model

    吉田 寛

    第56回 生物物理学会  2018.9 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:岡山   Country:Japan  

  • A model for analyzing phenomena in multicellular organisms with multivariable polynomials

    吉田 寛

    第54回生物物理学会  2016.11 

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    Event date: 2016.11

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:筑波   Country:Japan  

  • Polynomial-life model towards analysis of turnover and regeneration

    Hiroshi Yoshida

    第53回生物物理学会  2015.9 

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    Event date: 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:金沢   Country:Japan  

  • A model of multicellular organisms using multivariable polynomials ー Polynomial Life ー

    Hiroshi Yoshida

    数理生物学会  2015.8 

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    Event date: 2015.8

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:同志社大学   Country:Japan  

  • Toward analysis of multicell-turnover patterns by using multivariable polynomials

    吉田 寛

    第52回生物物理学会  2014.9 

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    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:札幌   Country:Japan  

  • 消去パラメータ付L システムを用いた赤血球と白血球の動的恒常性の再現

    石田航己 吉田寛

    2024年度数理生物学会  2024.9 

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    Presentation type:Oral presentation (general)  

    Venue:北大  

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MISC

  • 多細胞生物の再帰的増殖と細胞タイプ多様性の両立条件

    吉田寛、古澤力、金子邦彦

    生物物理 (中西印刷)   2007.2

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Professional Memberships

  • 生物物理学会

  • 数理生物学会

Research Projects

  • Polynomial-lifeモデルで探る肢のフィボナッチ比発生とセグメント再生

    Grant number:18K12036  2018.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 多細胞の多変数多項式モデルの構築で迫る動的恒常維持機構の原理と限界

    2014 - 2016

    Grants-in-Aid for Scientific Research  Grant-in-Aid for challenging Exploratory Research

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • Dachsous:Fatシグナル系実験に基づく再生方程式の導出

    Grant number:23124509  2011 - 2012

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 楕円曲線=代数方程式による多細胞起源の理解

    Grant number:21740077  2009 - 2011

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • コンパートメントモデルにおける薬物動態のラプラス空間上での代数方程式による解析

    Grant number:19790881  2007 - 2008

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

Class subject

  • 微分積分学Ⅱ

    2023.10 - 2024.3   Second semester

  • 数学演習B

    2023.4 - 2023.9   First semester

  • 微分積分学Ⅰ

    2023.4 - 2023.9   First semester

  • 応用数学Ⅳ

    2023.4 - 2023.6   Spring quarter

  • Bioinformatics, Advanced Course Ⅹ

    2023.4 - 2023.6   Spring quarter

  • 生命情報数理モデル特論

    2023.4 - 2023.6   Spring quarter

  • 微分積分学Ⅱ

    2022.10 - 2023.3   Second semester

  • 微分積分学Ⅱ

    2022.10 - 2023.3   Second semester

  • 微分積分学Ⅰ

    2022.4 - 2022.9   First semester

  • 微分積分学Ⅰ

    2022.4 - 2022.9   First semester

  • 応用数学Ⅳ

    2022.4 - 2022.6   Spring quarter

  • Bioinformatics, Advanced Course Ⅹ

    2022.4 - 2022.6   Spring quarter

  • 生命情報数理モデル特論

    2022.4 - 2022.6   Spring quarter

  • 応用数学Ⅳ

    2021.10 - 2021.12   Fall quarter

  • Bioinformatics, Advanced Course Ⅹ

    2021.10 - 2021.12   Fall quarter

  • 生命情報数理モデル特論

    2021.10 - 2021.12   Fall quarter

  • 生命情報数理モデル特論

    2021.10 - 2021.12   Fall quarter

  • 線形代数同演習

    2021.4 - 2022.3   Full year

  • 微分積分3

    2021.4 - 2021.9   First semester

  • 生命情報科学2

    2021.4 - 2021.6   Spring quarter

  • 応用数学Ⅳ

    2020.10 - 2020.12   Fall quarter

  • 生命情報数理モデル特論

    2020.10 - 2020.12   Fall quarter

  • Bioinformatics, Advanced Course Ⅹ

    2020.10 - 2020.12   Fall quarter

  • 生命情報数理モデル特論

    2020.10 - 2020.12   Fall quarter

  • 線形代数同演習

    2020.4 - 2021.3   Full year

  • 微分積分同演習

    2020.4 - 2021.3   Full year

  • 機能数理学概論Ⅰ

    2020.4 - 2020.9   First semester

  • 生命情報科学2

    2020.4 - 2020.6   Spring quarter

  • 日韓留学生予備コース

    2018.10 - 2019.3   Second semester

  • 微分積分学・同演習AB

    2018.4 - 2019.3   Full year

  • 数学展望

    2018.4 - 2018.9   First semester

  • 微分積分学・同演習III

    2018.4 - 2018.9   First semester

  • 線形代数

    2018.4 - 2018.9   First semester

  • 生命情報数理モデル特論(応用数学Ⅳ)

    2018.4 - 2018.6   Spring quarter

  • 日韓留学生予備コース

    2017.10 - 2018.3   Second semester

  • 数学展望

    2017.10 - 2018.3   Second semester

  • 微分積分学

    2017.10 - 2018.3   Second semester

  • 線形代数・同演習AB

    2017.4 - 2018.3   Full year

  • 線形代数

    2017.4 - 2017.9   First semester

  • 線形代数

    2016.10 - 2017.3   Second semester

  • 数理科学Ⅱ

    2016.10 - 2017.3   Second semester

  • 微分積分学・同演習AB

    2016.4 - 2017.3   Full year

  • 微分積分学・同演習Ⅲ

    2016.4 - 2016.9   First semester

  • 複素関数論

    2016.4 - 2016.9   First semester

  • 線形代数・同演習B

    2015.10 - 2016.3   Second semester

  • 日韓留学生予備コース

    2015.10 - 2016.3   Second semester

  • 微分積分学

    2015.4 - 2015.9   First semester

  • 複雑システム大意

    2015.4 - 2015.9   First semester

  • 微分積分学・同演習III

    2015.4 - 2015.9   First semester

  • 数学IA(常微分方程式)

    2014.10 - 2015.3   Second semester

  • 複雑システム大意

    2014.10 - 2015.3   Second semester

  • 線形代数・同演習AB

    2014.4 - 2015.3   Full year

  • 数理学講究第II (4年生 卒業研究)

    2014.4 - 2015.3   Full year

  • 微分積分続論

    2014.4 - 2014.9   First semester

  • 数理科学II

    2014.4 - 2014.9   First semester

  • 理系コア・数学II

    2014.4 - 2014.9   First semester

  • 数学IA(常微分方程式)

    2013.10 - 2014.3   Second semester

  • 線形代数・同演習

    2013.4 - 2014.3   Full year

  • 微分積分続論

    2013.4 - 2013.9   First semester

  • 理系コア・数学II

    2013.4 - 2013.9   First semester

  • 線形代数・同演習

    2012.4 - 2013.3   Full year

  • 微分積分・同演習

    2012.4 - 2013.3   Full year

  • MMA コース、数理モデル概論

    2011.10 - 2012.3   Second semester

  • 微分積分

    2011.4 - 2012.3   Full year

  • 線形代数

    2011.4 - 2012.3   Full year

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FD Participation

  • 2018.5   Role:Participation   Title:生物学科教育支援室の5年間とこれから

    Organizer:[Undergraduate school/graduate school/graduate faculty]

Social Activities

  • 出張講義

    佐賀西高校  佐賀県  2015.8

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    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • オープンキャンパス

    九州大学 数理学研究院  九大 伊都キャンパス  2013.8

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    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture