The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival

Niiro H, Maeda A, Kurosaki T, Clark EA

J Exp Med   2002.1

Comparing the safety and efficacy of nintedanib starting dose in patients with connective tissue disease-associated interstitial lung diseases. Reviewed International journal

Ayano M, Tsubouchi K, Suzuki K, Kimoto Y, Arinobu Y, Akashi K, Horiuchi T, Okamoto I, Niiro H.

Scand J Rheumatol   1 - 8   2024.4

No clear influence of treatment escalation on flare prevention in serologically active clinically quiescent patients with systemic lupus erythematosus: a retrospective cohort study. Reviewed International journal

Ayano M, Hirata A, Tokunaga S, Furuhashi H, Kimoto Y, Ono N, Arinobu Y, Nakashima N, Akashi K, Horiuchi T, Niiro H.

Rheumatol Int   2024.4

Establishing clinical remission criteria for giant cell arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis. Reviewed International journal

Sugihara T, Yoshifuji H, Uchida HA, Maejima Y, Watanabe Y, Tanemoto K, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Niiro H, Ishii T, Nakaoka Y, Harigai M.

Mod Rheumatol   34 ( 3 )   568 - 575   2024.3

Individual and population-level variability in HLA-DR associated immunogenicity risk of biologics used for the treatment of rheumatoid arthritis. Reviewed International journal

Sugiyama N, Terry FE, Gutierrez AH, Hirano T, Hoshi M, Mizuno Y, Martin W, Yasunaga SI, Niiro H, Fujio K, De Groot AS.

Front Immunol   15   2024.3

Effectiveness and safety of Sarilumab in patients with rheumatoid arthritis: A multicenter, retrospective, inverse probability of treatment-weighted analysis based on the FRAB-registry. Reviewed International journal

Harada H, Kondo M, Maeyama A, Fukuda T, Ikemura S, Shono E, Tsuru T, Inoue Y, Yoshizawa S, Niiro H, Nakashima Y.

Clin Rheumatol   43 ( 5 )   1447 - 1459   2024.3

Relationships between type 1 IFN signature and clinical features of the Newly-onset lupus patients in Japan. Reviewed International journal

Shirahama Y, Hashimoto A, Ono N, Takeyama Y, Maruyama A, Inoue T, Tada Y, Niiro H.

Mod Rheumatol   34 ( 2 )   346 - 351   2024.2

Immunosuppressive therapy and humoral response to third mRNA COVID-19 vaccination with a six-month interval in rheumatic disease patients Reviewed International journal

Kashiwado Y, Kimoto Y, Ohshima S, Sawabe T, Irino K, Nakano S, Hiura J, Yonekawa A, Wang Q, Doi G, Ayano M, Mitoma H, Ono N, Arinobu Y, Niiro H, Hotta T, Kang D, Shimono N, Akashi K, Takeuchi T, Horiuchi T

Rheumatology (Oxford)   63 ( 3 )   725 - 733   2024.1

GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region. Reviewed International journal

15 ( 1 )   319   2024.1

Recent advances in the treatment strategy for AAV improved outcomes with intensive GC tapering. Reviewed International journal

Ono N, Kai T, Takeyama Y, Inoue Y, Ueda N, Nagano S, Ohta S, Inoue H, Sawabe T, Chifu Y, Yoshizawa S, Oryoji K, Kimoto Y, Miyake K, Ayano M, Mitoma H, Arinobu Y, Miyamura T, Horiuchi T, Akashi K, Tada Y, Niiro H.

Int J Rheum Dis   27 ( 1 )   e15009   2024.1

Determination of the factors associated with antigen-specific CD4+ T-cell response to BNT162b2 in patients with rheumatoid arthritis Reviewed International journal

Sagawa F, Yamada H, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kondo M, Nakashima Y, Akashi K, Horiuchi T, Niiro H

RMD Open   10 ( 1 )   e003693   2024.1

Low avidity observed for anti-citrullinated peptide antibody is not a general phenomenon for autoantibodies Reviewed International journal

Yamada H, Haraguchi A, Tsuru T, Kondo M, Sagawa F, Niiro H, Nakashima Y

Ann Rheum Dis   82 ( 12 )   1637 - 1638   2023.12

Granzyme-K- and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease Reviewed International journal

Koga R, Maehara T, Aoyagi R, Munemura R, Murakami Y, Doi A, Kono M, Yamamoto H, Niiro H, Kiyoshima T, Tanabe M, Nakano T, Matsukuma Y, Kawano M, Stone JH, Pillai S, Nakamura S, Kawano S

J Allergy Clin Immunol   2023.12

Anti-dsDNA IgE induces IL-4 production from basophils, potentially involved in B-cell differentiation in systemic lupus erythematosus Reviewed International journal

Fujimoto S, Arinobu Y, Miyawaki K, Ayano M, Mitoma H, Kimoto Y, Ono N, Akashi K, Horiuchi T, Niiro H

Rheumatology (Oxford)   62 ( 10 )   3480 - 3489   2023.10

Peripheral helper-T-cell-derived CXCL13 is a crucial pathogeneic factor in idiopathic multicentric Castleman disease Reviewed International journal

Harada T, Kikushige Y, Miyamoto T, Uno K, Niiro H, Kawakami A, Koga T, Akashi K, Yoshizaki K

Nt Commun   14 ( 1 )   6959   2023.10

Safety and efficacy of switching immunosuppressive drugs for maintenance treatment in patients with systemic lupus erythematosus: a retrospective cohort study. Reviewed International journal

Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Mod Rheumatol   33 ( 5 )   961 - 967   2023.8

Immunosuppressive therapy and humoral response to third mRNA COVID-19 vaccination with a six-month interval in rheumatic disease patients. Reviewed International journal

Kashiwado Y, Kimoto Y, Ohshima S, Sawabe T, Irino K, Nakano S, Hiura J, Yonekawa A, Wang Q, Doi G, Ayano M, Mitoma H, Ono N, Arinobu Y, Niiro H, Hotta T, Kang D, Shimono N, Akashi K, Takeuchi T, Horiuchi T.

Rheumatology   2023.6

Antibody Response to SARS-CoV-2 mRNA vaccines in patients with rheumatic diseases in Japan: Interim analysis of a multicenter cohort study. Reviewed International journal

Kashiwado Y, Kimoto Y, Sawabe T, Irino K, Nakano S, Hiura J, Wang Q, Kawano S, Ayano M, Mitoma H, Ono N, Arinobu Y, Niiro H, Hotta T, Kang D, Akashi K, Ohshima S, Takeuchi T, Horiuchi T.

Mod Rheumatol   33 ( 2 )   367 - 372   2023.3

Anti-dsDNA IgE induces IL-4 production from basophils, potentially involved in B-cell differentiation in systemic lupus erythematosus. Invited Reviewed International journal

Fujimoto S, Arinobu Y, Miyawaki K, Ayano M, Mitoma H, Kimoto Y, Ono N, Akashi K, Horiuchi T, Niiro H.

Rheumatology   2023.2

CEACAM 1, 3, 5 and 6 –positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis. Reviewed International journal

13   1016914   2022.10

Establishing clinical remission criteria and the framework of a Treat-To-Target algorithm for Takayasu arteritis: results of a Delphi exercise carried out by an expert panel of the Japan research committee of the ministry of health, labour, and welfare for intractable vasculitis. Reviewed International journal

Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasagawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M.

Mod Rheumatol   32 ( 5 )   930 - 937   2022.8

Clinical course of patients with rheumatoid arthritis who continue or discontinue biologic therapy after hospitalization for infection: a retrospective observational study. Reviewed International journal

Kashiwado Y, Kiyohara C, Kimoto Y, Nagano S, Sawabe T, Oryoji K, Mizuki S, Nishizaka H, Yoshizawa S, Yoshizawa S, Tsuru T, Inoue Y, Ueda N, Ota S, Miyamura T, Tada Y, Niiro H, Akashi K, Horiuchi T.

Arthritis Res Ther   24 ( 1 )   131   2022.6

Comparative efficacy and safety of mizoribine and mycophenolate mofetil for treating systemic lupus erythematosus: a retrospective cohort study. Reviewed International journal

Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Ther Adv Musculoskelet Dis   2022.5

Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study. Reviewed International journal

Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang YF, Amano K, Park DJ, Yang W, Tada Y, Lau YL, Yamaji K, Zhu Z, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y, JRC on IONFH; Yamamoto K, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC.

Ann Rheum Dis.   81 ( 9 )   1273 - 1280   2022.5

Activation of caspase-1 is mediated by stimulation of interferon genes and NLR family pyrin domain containing 3 in monocytes of active systemic lupus erythematosus. Reviewed International journal

Inokuchi S, Mitoma H, Kawano S, Ayano M, Kimoto Y, Akahoshi M, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Clin Exp Rheumatol   40 ( 3 )   522 - 531   2022.3

Novel Susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus. Reviewed International journal

Suetsugu H, Kim K, Yamamoto T, Bang SY, Sakamoto Y, Shin JM, Sugano N, Kim JS, Mukai M, Lee YK, Ohmura K, Park DJ, Takahashi D, Ahn GY, Karino K, Kwon YC, Miyamura T, Kim J, Nakamura J, Motomura G, Kuroda T, Niiro H, Miyamoto T, Takeuch T, Ikari K, Amano K, Tada Y, Yamaji K, Shimizu M, Atsumi T, Seki T, Tanaka Y, Kubo T, Hisada R, Yoshioka T, Yamazaki M, Kabata T, Kajino T, Ohta Y, Okawa T, Naito Y, Kaneuji A, Yasunaga Y, Ohzono K, Tomizuka K, Koido M, Matsuda K, Okada Y, Suzuki A, Kim BJ, Kochi Y, Lee HS, Ikegawa S, Bae SC, Terao C.

Hum Mol Genet   31 ( 7 )   1082 - 1095   2022.3

TNFR2 signaling enhances suppressive abilities of human circulating T follicular regulatory cells. Reviewed International journal

Kawano S, Mitoma H, Inokuchi S, Yamauchi Y, Yokoyama K, Nogami J, Semba Y, Ayano M, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

J Immunol   208 ( 5 )   1057 - 1065   2022.3

Hydroxychloroquine versus tacrolimus for the treatment of persistently active systemic lupus erythematosus. Reviewed International journal

Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Mod Rheumatol   32 ( 2 )   345 - 350   2022.2

Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry. Reviewed International journal

Fujiwara T, Kondo M, Yamada H, Haraguchi A, Fujimura K, Sakuraba K, Kamura S, Fukushi JI, Miyahara H, Inoue Y, Tsuru T, Shuto T, Yoshizawa S, Suematsu E, Miyamura T, Ayano M, Mitoma H, Arinobu Y, Niiro H, Ohishi M, Hirata A, Tokunaga S, Takada A, Hara D, Tsushima H, Akasaki Y, Ikemura S, Sueishi T, Toya M, Sakuragi T, Tsutsui T, Kai K, Arisumi S, Nakashima Y.

Arthritis Res Ther   24 ( 1 )   53   2022.2

Predictive factors of fetal and maternal pregnancy outcomes in Japanese patients with systemic lupus erythematosus. Reviewed International journal

Irino K, Arinobu Y, Ayano M, Kawano S, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H.

Lupus   30 ( 10 )   1637 - 1643   2021.9

HLA-B52 allele in giant cell arteritis may indicate diffuse large-vessel vasculitis formation: a retrospective study. Reviewed International journal

Kushimoto K, Ayano M, Nishimura K, Nakano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Arthritis Res Ther   23 ( 1 )   238   2021.9

Association of elevated serum soluble CD226 levels with the disease activity and flares of systemic lupus erythematosus. Reviewed International journal

Nakano M, Ayano M, kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Sci Rep   11 ( 1 )   16162   2021.8

Increased proportion of CD226+ B cells is associated with the disease activity and prognosis of systemic lupus erythematosus. Reviewed International journal

Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.

Front Immunol   12   713225   2021.7

Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus. Reviewed International journal

Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang Y, Amano K, Park DJ, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y; Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head, Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC.

Ann Rheum Dis   80 ( 5 )   632 - 640   2021.5

Outcomes of methotrexate-associated lymphoproliferative disorders in rheumatoid-arthritis patients treated with disease-modifying anti-rheumatic drugs. Invited Reviewed International journal

Harada T, Iwasaki H, Muta T, Urata S, Sakamoto A, Kohno K, Takase K, Miyamura T, Sawabe T, Asaoku H, Oryoji K, Fujisaki T, Mori Y, Yoshimoto G, Ayano M, Mitoma H, Miyamoto T, Niiro H, Yamamoto H, Oshiro Y, Miyoshi H, Ohshima K, Takeshita M, Akashi K, Kato K.

Brit J Haematol   194 ( 1 )   101 - 110   2021.4

Autoimmune manifestations associated with myelodysplastic syndrome predict a poor prognosis. Reviewed International journal

Arinobu Y, Kashiwado Y, Miyawaki K, Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Miyamoto T, Horiuchi T, Akashi K, Niiro H.

Medicine (Baltimore).   100 ( 13 )   e25406   2021.4

Human PD-1hiCD8+ T cells are a cellular source of IL-21 in rheumatoid arthritis Reviewed International journal

Higashioka K, Yoshimura M, Sakuragi T, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Horiuchi T, Akashi K, Niiro H

Front Immunol   12   654623   2021.3

Rituximab maintenance therapy for patients with antineutrophil cytoplasmic antibody-associated vasculitis in Japan. Reviewed International journal

Takeyama Y, Ono N, Shirahama Y, Inoue Y, Tanaka A, Ueda N, Nishimura N, Nagano S, Uchino A, Miyamura T, Oryoji K, Inoue H, Maruyama A, Ota S, Yoshizawa S, Sawabe T, Himuro N, Miyake K, Kimoto Y, Horiuchi T, Mitoma H, Niiro H, Takamori A, Tada Y.

Mod Rheumatol   31 ( 2 )   408 - 416   2021.3

The association of airway comorbidities with the clinical phenotypes and outcomes of ANCA-associated vasculitis patients. Reviewed International journal

Ono N, Inoue Y, Miyamura T, Ueda N, Nagano S, Inoue H, Oryoji K, Ota SI, Sawabe T, Yoshizawa S, Takeyama Y, Sadanaga Y, Takamori A, Kimoto Y, Miyake K, Horiuchi T, Nakashima H, Niiro H, Tada Y.

J Rheumatol   48 ( 3 )   417 - 425   2021.3

Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis Reviewed International journal

Nakayama T, Yoshimura M, Higashioka K, Miyawaki K, Ota Y, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Akashi K, Horiuchi T, Niiro H

Cell Immunol   360   104263   2021.2

First case of pyrin-associated autoinflammation with neutrophilic dermatosis complicated by amyloidosis. Reviewed International journal

Kiyota M, Oya M, Ayano M, Niiro H, Iwasaki T, Fujiwara M, Oda Y, Fujimoto K, Ida H.

Rheumatology (Oxford).   59 ( 9 )   e41 - e43   2020.9

Methotrexate enhances apoptosis of transmembrane TNF-expressing cells treated with an anti-TNF agent. Reviewed International journal

Wang Q, Oryoji D, Mitoma H, Kimoto Y, Koyanagi M, Ayano M, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T.

Front Immunol   11   2042   2020.8

Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica. Reviewed International journal

Ayano M, Arinobu Y, Tsukamoto H, Ota SI, Misaki K, Nishimura K, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H.

Rheumatol Int.   40 ( 7 )   1101 - 1109   2020.7

Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease Reviewed International journal

Higashioka K, Ota Y, Maehara T, Moriyama M, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Horiuchi T, Nakamura S, Akashi K, Niiro H

BMC Immunol   21 ( 1 )   31   2020.6

Generation of a novel CD30+ B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis Reviewed International journal

Higashioka K, Kikushige Y, Ayano M, Kimono Y, Mitoma H, Kikukawa M, Akahoshi M, Arinobu Y, Horiuchi T, Akashi K, Niiro H

Clin Exp Immunol   201 ( 3 )   233 - 243   2020.6

Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells Reviewed International journal

Inokuchi S, Mitoma H, Kawano S, Nakano S, Ayano M, Kimoto Y, Akahoshi M, Arinobu Y, Tsukamoto H, Akashi K, Horiuchi T, Niiro H

J Immunol   204 ( 8 )   2088 - 2097   2020.4

Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study Reviewed International journal

Nakaoka Y, Isobe M, Tanaka Y, Ishii T, Ooka S, Niiro H, Tamura N, Banno S, Yoshifuji H, Sakata Y, Kawakami A, Atsumi T, Furuta S, Kohsaka H, Suzuki K, Hara R, Maejima Y, Tsukamoto H, Takasaki Y, Yamashita K, Okada N, Yamakido S, Takei S, Yokota S, Nishimoto N

Rheumatology   59 ( 9 )   2427 - 2434   2020.1

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines Reviewed International journal

Takaki-Kuwahara A, Arinobu Y, Miyawaki K, Yamada H, Tsuzuki H, Irino K, Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Tsukamoto H, Horiuchi T, Niiro H, Akashi K

Arthritis Res Ther   21 ( 1 )   198   2019.8

CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan. Invited Reviewed International journal

Ayano M, Tsukamoto H, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Miyamoto T, Horiuchi T, Niiro H, Nagafuji K, Harada M, Akashi K

Arthritis Res Ther   2019.1

Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study. Reviewed International journal

Otsuka Y, Kiyohara C, Kashiwado Y, Sawabe T, Nagano S, Kimoto Y, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T

PLoS One   2018.4

Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration. Reviewed International journal

Wakasaki T, Niiro H, Jabbarzadeh-Tabrizi S, Ohashi M, Kimitsuki T, Nakagawa T, Komune S, Akashi K

BMC Neurosci   18   64   2017.6

Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes. Reviewed International journal

Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota S-I, Ota Y, Mitoma H, Akahoshi H, Mori Y, Iwasaki H, Niiro H, Tsukamoto H, Akashi K

Immunology   150 ( 1 )   64 - 73   2017.1

Safety, Pharmacokinetics and Pharmacodynamics of Epratuzumab in Japanese Patients with Moderate-to-Severe Systemic Lupus Erythematosus: Results from a Phase 1/2 Randomized Study. Reviewed International journal

Tomomi Tsuru, Yoshiya Tanaka, Mitsumasa Kishimoto, Kazuyoshi Saito, Seiji Yoshizawa, Yoshinari Takasaki, Tomoya Miyamura, Hiroaki Niiro, Shinji Morimoto, Junichi Yamamoto, Rocio Lledo-Garcia, Jing Shao, Shuichiro Tatematsu, Osamu Togo, Takao Koike

Mod Rheumatol.   26 ( 1 )   87 - 93   2016.1

Brodalumab, a human anti-interleukin-17-receptor antibody in the treatment of Japanese patients with moderate-to-severe plaque psoriasis: Efficacy and safety results from a phase II randomized controlled study. Reviewed International journal

Hidemi Nakagawa, Hiroaki Niiro, Kenji Ootaki

J Dermatol Sci.   81 ( 1 )   44 - 52   2016.1

Increased CD226 Expression on CD8+ T Cells Is Associated with Upregulated Cytokine Production and Endothelial Cell Injury in Patients with Systemic Sclerosis. Reviewed International journal

J Immunol.   195 ( 3 )   892 - 900   2015.8

Characteristics of MPO-ANCA-positive granulomatosis with polyangiitis: a retrospective multi-center study in Japan Reviewed International journal

Nobuyuki Ono, Hiroaki Niiro, Akira Ueda, Takuya Sawabe, Hiroaki Nishizaka, Isao Furugo, Seigi Yoshizawa, Shigeru Yoshizawa, Hiroshi Tsukamoto, Chikako Kiyohara, Yoshifumi Tada, Takahiko Horiuchi

Rheumatol Int   35 ( 3 )   555 - 559   2015.3

Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A Reviewed International journal

Kensuke Oryoji, Chikako Kiyohara, Takahiko Horiuchi, Hiroshi Tsukamoto, Hiroaki Niiro, Terufumi Shimoda, Koichi Akashi, Toshihiko Yanase

MODERN RHEUMATOLOGY   24 ( 1 )   86 - 92   2014.1

The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α. Reviewed International journal

19 ( 6 )   1224 - 1231   2013.5

PU.1 is a potent tumor suppressor in classical Hodgkin lymphoma cells. Reviewed International journal

Yuki H, Ueno S, Tatetsu H, Hiroaki Niiro, Tadafumi Iino, Endo S, Kawano Y, Komohara Y, Takeya M, Hata H, Okada S, Watanabe T, koichi akashi, Mitsuya H, Okuno Y

Blood   121 ( 6 )   962 - 970   2013.3

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity. Reviewed International journal

Atsushi Tanaka, Hiroshi Tsukamoto, Hiroaki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Inoue Yasushi, Yojiro Arinobu, Hiroaki Niiro, Takahiko Horiuchi, koichi akashi

Arthritis Res Ther   14 ( 6 )   R244   2012.11

Amplification of toll-like receptor-mediated signaling through Syk in human B activation. Reviewed International journal

Shigeru Iwata, Kunihiro Yamaoka, Hiroaki Niiro, Kazuhisa Nakano, Sheau-Pey Wang, koichi akashi, Yoshiya Tanaka

J Allergy Clin Immunol   129 ( 6 )   1594 - 1601   2012.6

Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis: predominant reconstitution of Th1 CD4+ T cells. Reviewed International journal

Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, and Akashi K

Rheumatology   50 ( 5 )   2011.5

Interaction between Toll-like receptors and natural iiller cells in the destruction of bile ducts in primary biliary cirrhosis. Reviewed International journal

Shimoda S, Harada K, Niiro H, Shirabe K, Taketomi A, Maehara Y, Tsuneyama K, Nakanuma Y, Leung P, Ansari AA, Gershwin ME, and Akashi K

Hepatology   53 ( 4 )   2011.4

A critical role of c-Cbl interacting protein of 85 kDa in the development and progression of head and neck squamous cell carcinomas via the Ras-ERK pathway. Reviewed International journal

Wakasaki T, Masuda M, Niiro H, Jabbarzadeh-Tabrizi S, Noda K, Taniyama T, Komune S, and Akashi K

Neoplasia   12 ( 10 )   2010.10

Tacrolimus is effective for lupus nephritis patients with persistent proteinuria Reviewed International journal

Uchino A, Tsukamoto H, Nakashima H, Yoshizawa S, Furugo I, Mitoma H, Oryoji K, Shimoda T, Niiro H, Tada Y, Yano T, Nonaka T, Oishi R, Akashi K, and Horiuchi T

Clin Exp Rheumatol   28 ( 1 )   2010.1

CX3CL1 (FRACTALKINE): A SIGNPOST FOR BILIARY INFLAMMATION IN PRIMARY BILIARY CIRRHOSIS. Reviewed International journal

Shimoda S, Harada K, Niiro H, Taketomi A, Maehara Y, Tsuneyama K, Kikuchi K, Nakanuma Y, Mackay IR, Gershwin EM, and Akashi K

Hepatology   2009.9

PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL. Reviewed International journal

Ueno S, Tatetsu H, Hata H, Iino T, Niiro H, Akashi K, Tenen DG, Mitsuya H, and Okuno Y

Oncogene   2009.9

Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells. Reviewed International journal

Koyama M, Hashimoto D, Aoyama K, Matsuoka K, Karube K, Niiro H, Harada M, Tanimoto M, Akashi K, and Teshima T

Blood   2009.2

Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor. Reviewed International journal

Mori Y, Iwasaki H, Kohno K, Yoshimoto G, Kikushige Y, Okeda A, Uike N, Niiro H, Takenaka K, Nagafuji K, Miyamoto T, Harada M, Takatsu K, Akashi K

J Exp Med   2009.1

Human Flt3 Is Expressed at the Hematopoietic Stem Cell and the Granulocyte/Macrophage Progenitor Stages to Maintain Cell Survival

Kikushige Y, Yoshimoto G, Miyamoto T, Iino T, Mori Y, Iwasaki H, Niiro H, Takenaka K, Nagafuji K, Harada M, Ishikawa F, Akashi K

J Immunol   2008.6

抗CD20抗体 リツキシマブ (リウマチ・膠原病治療薬ハンドブック)

新納　宏昭（ Role： Joint author）

文光堂  2018.4 

インターロイキンー2(IL-2)およびIL-2受容体 日本臨牀 68巻（増刊号７：広範囲 血液・尿化学検査，免疫学的検査（４））

新納　宏昭（ Role： Sole author）

日本臨床  2010.7 

インターロイキンー３(IL-3), IL-4, IL-5 日本臨牀 68巻（増刊号７：広範囲 血液・尿化学検査，免疫学的検査（４））

新納宏昭（ Role： Sole author）

日本臨床  2010.7 

組織球増殖症

新納宏昭、赤司浩一（ Role： Joint author）

朝倉書店  2007.7 

ADAMTS13活性低下を伴わないTMA Invited

新納 宏昭

第59回日本リウマチ学会総会・学術集会  2015.4 

関節リウマチ患者におけるトシリズマブの有効性および酸化ストレスマーカー変化量の検討 ー 52週解析から得られた知見 ー

新納 宏昭

第59回日本リウマチ学会総会・学術集会  2015.4 

健常人ならびにSLE患者B細胞におけるIRAK-M発現とその機能

新納 宏昭, JABBARZADEH TABRIZI SIAMAK, 大田俊一郎, 植木尚子, 廣崎友里, 野田久美子, 上田尚靖, 田中淳, 上田彰, 久本仁美, 綾野雅宏, 押領司大助, 赤星 光輝, 有信 洋二郎, 塚本 浩, 堀内 孝彦, 赤司 浩一

第57回日本リウマチ学会総会 学術集会  2013.4 

健常人ならびにSLE患者B細胞におけるIRAK発現とその役割

新納宏昭、ジャバルザデ　タブリジ　シアマック、大田俊一郎、野田久美子、上田尚靖、田中淳、藤健太郎、井上靖、有信洋二郎、塚本浩、堀内孝彦、赤司浩一

第55回日本リウマチ学会総会  2011.7 

ヒトB細胞におけるIRAK発現調節と自己免疫疾患におけるその関与

新納宏昭、Jabbarzadeh-Tabrizi Siamak、相澤久美子、上田尚靖、押領司健介、三苫弘喜、井上靖、有信洋二郎、塚本浩、堀内孝彦、赤司浩一

第54回日本リウマチ学会総会  2010.4 

A vital role of CIN85 in Cbl-mediated regulation of B cell survival, growth and differentiation International conference

Hiroaki Niiro, Siamak Jabbarzadeh-Tabrizi, Kumiko Noda, Yasushi Inoue, Yojiro Arinobu, Koichi Akashi

2010 Keystone Symposia  2010.2 

CblのB細胞機能制御におけるCIN85の役割/A vital role of CIN85 in Cbl-mediated regulation of B cell functions

第３９回日本免疫学会総会•学術集会  2009.12 

Critical role of CIN85 in Cbl-mediated regulation of B cell function after antigen receptor stimulation International conference

Hiroaki Niiro, Siamak Jabbarzadeh-Tabrizi, Kumiko Aizawa, Yasushi Inoue, Yojiro Arinobu, Koichi Akashi

96th annual meeting AAI Immunology 2009  2009.5 

抗原受容体シグナルによる正常ならびにSLE B細胞サブセットの生存の制御

新納宏昭、ジャバルザデ　タブリジ　シアマック、相澤久美子、三苫弘喜、井上　靖、有信　洋二郎、塚本　浩、堀内孝彦、赤司浩一

第53回日本リウマチ学会総会  2009.4 

SLE B細胞機能異常における新規アダプター分子CIN85の関与

新納宏昭、ジャバルザデシアマック、有信洋二郎、小野伸之、赤司浩一

第52回日本リウマチ学会総会  2008.4 

新規アダプター分子CIN85によるヒトB細胞の機能制御機構

新納宏昭、ジャバルザデシアマック、吉本五一、赤司浩一

第51回日本リウマチ学会総会  2007.4 

Elucidation of molecular mechanism of Breg induction in autoimmune diseases. International conference

Shun-ichiro Ota, Hiroaki Niiro, Naoko Ueki, Yuri Hirosaki, Hirofumi Tsuzuki, Kumiko Noda, JABBARZADEH TABRIZI SIAMAK, Atsushi Tanaka, Hiroki Mitoma, Yojiro Arinobu, Mitsuteru Akahoshi, Hiroshi Tsukamoto, Koichi Akashi

ACR annual meeting 2014  2014.11 

Cblアダプター分子CIN85によるB細胞機能制御とSLE患者B細胞における役割

新納 宏昭, ジャバルザデ　タブリジ　シアマック, 大田　俊一郎, 植木　尚子, 野田　久美子, 上田　尚靖, 田中　淳, 上田　彰, 綾野　雅宏, 久本　仁美, 古川　牧緒, 井上 靖, 有信 洋二郎, 塚本 浩, 堀内 孝彦, 赤司 浩一

第56回日本リウマチ学会総会  2012.4 

抗BAFF抗体、TACI-Ig Invited

新納 宏昭

第56回日本リウマチ学会総会  2012.4 

関節リウマチ患者におけるトシリズマブの有効性および酸化ストレスマーカー変化量の検討　—中間解析から得られた知見 -

新納 宏昭, 塚本 浩, 有信 洋二郎, 赤星 光輝, 木本 泰孝, 藤健太郎, 押領司健介, 井上靖, 澤部琢哉, 永野修司, 西坂浩明, 吉澤誠司, 多田芳史, 吉澤滋, 大塚毅, 上田章, 　中島衡, 堀内 孝彦, 赤司 浩一

第58回日本リウマチ学会総会  2014.4 

エフェクターB細胞 Invited

新納 宏昭

第42回日本臨床免疫学会総会  2014.9 

Pathogenic role of CXC chemokine receptor 3-positive B cells in bone destruction of rheumatoid arthritis. International conference

Yuri Hirosaki, Hiroaki Niiro, Shun-ichiro Ota, Naoko Ueki, Hirofumi Tsuzuki, JABBARZADEH TABRIZI SIAMAK, Kumiko Noda, Hiroki Mitoma, Mitsuteru Akahoshi, Yojiro Arinobu, Hiroshi Tsukamoto, Koichi Akashi

ACR annual meeting 2014  2014.11 

RA病態におけるIL-6阻害の意義を考える

新納 宏昭

第67回九州リウマチ学会  2024.3 

関節リウマチ治療におけるTNF阻害の意義

新納 宏昭

第67回九州リウマチ学会  2024.3 

自己抗体から考える関節リウマチの治療戦略

新納 宏昭

第38回日本臨床リウマチ学会  2023.11 

自己免疫疾患におけるB細胞異常と治療戦略 Invited

新納 宏昭

第51回日本臨床免疫学会総会  2023.10 

SLE治療における1型IFN制御の意義

新納 宏昭

第66回九州リウマチ学会  2023.9 

SLEの病態メカニズムを紐解く～Ⅰ型IFNの役割を含めて～

新納 宏昭

第58回日本臨床分子医学会学術集会  2023.4 

T-bet+ B細胞 Invited

新納 宏昭

第50回日本臨床免疫学会総会  2022.10 

リウマチ膠原病診療に重要な免疫の知識 Invited

新納 宏昭

第66回日本リウマチ学会総会・学術集会  2022.4 

肺病変・慢性感染症合併の関節リウマチ患者における生物学的製剤の使用

吉村 元樹、三嶋 耕司、綾野 雅宏、木本 泰孝、三苫 弘喜、赤星 光輝、有信 洋二郎、赤司 浩一、堀内 孝彦、新納 宏昭

第64回日本リウマチ学会総会学会  2020.8 

実臨床におけるべリムマブ使用下でのSLE患者の臨床経過の検討

吉村 元樹、三嶋 耕司、綾野 雅宏、木本 泰孝、三苫 弘喜、赤星 光輝、有信 洋二郎、赤司 浩一、堀内 孝彦、新納 宏昭

第64回日本リウマチ学会総会学会  2020.8 

T cell: a major protagonist in cancer, infection and autoimmunity

2020.8 

関節リウマチ治療におけるJAK阻害剤の役割

新納 　宏昭

第61回九州リウマチ学会  2021.3 

Type I and type II anti-CD20

Hiroaki Niiro

The 65th annual scientific meeting of the Japan college of rheumatology  2021.4 

同一模擬患者による臨床実習後OSCEトライアルの取り組み

@伊東 こずえ、@菊川 誠、@新納 宏昭

第51回日本医学教育学会大会  2019.7 

Tumor Necrosis Factor Receptor 2 Signaling Potentiates Proliferation and Suppressive Activities of Follicular Regulatory T Cells International conference

Shotaro Kawano, Hiroki Mitoma, Shoichiro Inokuchi, Masahiro Ayano, Yasutaka Kimoto, Mitsuteru Akahoshi, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi and Hiroaki Niiro

2019 ACR/ARP Annual Meeting  2019.11 

Identification of IFN-γ-producing Effector B Cells in Humans: Their Relevance to the Pathogenesis of Systemic Lupus Erythematosus International conference

2019.11 

高齢者における膠原病・リウマチ性疾患 Invited

新納 宏昭

第20回日本病院総合診療医学会学術総会  2020.2 

Distinct Roles of Tfh2, SLAMF7+ Tfh1 Cells and Th1 Cells in the Pathogenesis of IgG4-RD International conference

Kazuhiko Higashioka, Masahiro Ayano, Yasutaka Kimoto, Hiroki Mitoma, Mitsuteru Akahoshi, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi and Hiroaki Niiro.

2018 ACR/ARHP Annual Meeting  2018.10 

関節リウマチにおけるIL-21産生性CD8+T細胞の役割

東岡 和彦、中山 剛志、三嶋 耕司、綾野 雅宏、木本 泰孝、三苫 弘喜、赤星 光輝、有信 洋二郎、赤司 浩一、堀内 孝彦、新納 宏昭

第62回日本リウマチ学会総会・学術集会  2018.4 

大型血管炎の病態とサイトカインの役割 Invited

新納　宏昭

第45回日本臨床免疫学会総会  2017.9 

Role of the chemokine receptor CXCR3 in the function of regulatory B cells in patients with SLE International conference

Shun-ichiro Ota, Hiroaki Niiro, Naoko Ueki, Yuri Hirosaki, Hirofumi Tsuzuki, Siamak Jabbarzadeh-Tabrizi, Tsuyoshi Nakayama, Koji Mishima, Ayako Takaki, Hiroki Mitoma, Mitsuteru Akahoshi, Yojiro Arinobu, Hiroshi Tsukamoto, koichi akashi

2015 ACR/ARHP annual meeting  2015.11 

関節リウマチの骨破壊に寄与するRANKL 発現エフェクターB細胞の機能解析

廣崎 友里, 新納 宏昭, 大田 俊一郎, 植木　尚子, 中山 剛志, 三嶋 耕司, 猪口 翔一朗, 髙木 綾子, 中川 仁, 中野 翔太, 押領司 大助, 綾野 雅宏, 田中 淳, 三苫 弘喜, 赤星 光輝, 有信 洋二郎, 山田 久方, 久木田 明子, 塚本 浩

第59回日本リウマチ学会総会・学術集会  2015.4 

健常人ならびにSLE患者における制御性B細胞の比較検討

大田俊一郎、新納宏昭、Siamak Jabbarzadeh-Tabrizi、野田久美子、上田尚靖、田中淳、藤健太郎、井上靖、有信洋二郎、塚本浩、堀内孝彦、赤司浩一

第55回日本リウマチ学会総会  2011.7 

Defective induction of regulatory B cells (Breg) in RA patients International conference

Shun-ichiro Ota, Hiroaki Niiro, Hirofumi Tsuzuki, Naoko Ueki, Siamak Jabbarzadeh-Tabrizi, Yasushi Inoue, Yojiro Arinobu, Hiroshi Tsukamoto, Takahiko Horiuchi, and Koichi Akashi

2012 Keystone Symposia  2012.1 

Elucidation of the signaling pathways to induce human regulatory B cells International conference

Shun-ichiro Ota, Hiroaki Niiro, Hirofumi Tsuzuki, Siamak Jabbarzadeh-Tabrizi, Kumiko Noda, Yasushi Inoue, Yojiro Arinobu, Koichi Akashi

2011 Keystone Symposia  2011.4 

アダプター分子CIN85によるT細胞機能制御と自己免疫疾患へのその関与

相澤久美子、新納宏昭、Jabbarzadeh-Tabrizi Siamak、藤健太郎、押領司健介、井上靖、有信洋二郎、塚本浩、堀内孝彦、赤司浩一

第54回日本リウマチ学会総会  2010.4 

IL-25(IL-17E)レセプターは、骨髄球系前駆細胞に発現する

有信洋二郎、新納宏昭、相澤久美子、上田尚靖、藤健太郎、押領司健介、三苫弘喜、井上靖、塚本浩、堀内孝彦、赤司浩一

第54回日本リウマチ学会総会  2010.4 

関節リウマチ患者と健常人におけるB細胞のRANKL発現の比較検討

廣崎友里, 新納 宏昭, 大田俊一郎, 植木尚子, 綾野雅宏, 赤星 光輝, 有信 洋二郎, 塚本 浩, 堀内 孝彦, 赤司 浩一

第41回日本臨床免疫学会総会  2013.11 

関節リウマチにおけるB細胞滑膜炎と臨床フェノタイプ

新納 宏昭

リウマチ科   2021.4

巨細胞性動脈炎治療のメタ解析

新納 宏昭

リウマチ科   2019.9

重症強皮症に対するmyeloablative autologous stem cell transplantation

綾野雅宏、三苫弘喜、新納宏昭

リウマチ科   2019.4

リウマチ性類縁5疾患の最新知識 キャッスルマン病

新納 宏昭

臨床リウマチ   2019.1

ブロダルマブ

新納　宏昭

新興医学出版社   2018.9

自己免疫疾患におけるエフェクターB細胞.

新納 宏昭

日本臨床免疫会誌   2015.5

B細胞と自己免疫疾患

新納 宏昭

九州リウマチ   2014.9

全身性エリテマトーデスにおけるリンパ球異常

新納 宏昭, 赤司 浩一

腎と透析   2013.1

抗BAFF抗体，TACI-Ig

新納 宏昭

医薬ジャーナル   2012.6

SLEにおけるinterferon signature：発見から臨床試験までの道のり

新納宏昭、堀内孝彦

リウマチ科   2010.4

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1

Niiro H, and Clark EA

Immunity   2003.11

Regulation of B-cell fate by antigen-receptor signals

Niiro H, Clark EA

Nat Rev Immunol   2002.12

血管炎症候群の症候と診断　 巨細胞性動脈炎 (解説)

綾野 雅宏、新納 宏昭

2022.8

免疫系細胞のシグナル伝達と病態

新納　宏昭

日本臨牀   2022.4

SLEに対するepratuzumabの効果

中山 剛志, 新納 宏昭, 塚本 浩, 堀内 孝彦

リウマチ科   2015.4

BCRシグナルの制御とE3ユビキチンリガーゼおよびその関連分子

新納宏昭

臨床免疫•アレルギー科   2011.8

Aicardi-Goutieres syndrome (AGS)の遺伝子異常とそのphenotype-SLEの病因にせまれるか？

有信洋二郎、新納宏昭、堀内孝彦

リウマチ科   2011.4

自己免疫疾患と炎症

永淵正法、塚本浩、新納宏昭、小林隆志

細胞工学   2010.8

新規１型インターフェロン産生細胞と自己免疫

小野伸之、新納宏昭、堀内孝彦

2008.12

日本血液学会

日本免疫学会

日本リウマチ学会

座長

第51回日本免疫学会  （ 熊本城ホール（熊本県） ） 2022.12

Screening of academic papers

Role(s)： Peer review

2022

Screening of academic papers

Role(s)： Peer review

2021

Screening of academic papers

Role(s)： Peer review

2020

座長

第63回 日本リウマチ学会総会•学術集会  （ 国立京都国際会館/グランドプリンスホテル京都 ） 2019.4

座長

第63回 日本リウマチ学会総会•学術集会  （ グランドプリンスホテル京都 ） 2019.4

Screening of academic papers

Role(s)： Peer review

2019

座長

第62回 日本リウマチ学会総会•学術集会  （ 東京国際フォーラム ） 2018.4

Screening of academic papers

Role(s)： Peer review

2018

Screening of academic papers

Role(s)： Peer review

2017

Screening of academic papers

Role(s)： Peer review

2016

座長（Chairmanship）

第43回 日本臨床免疫学会総会  （ 神戸国際会議場 ） 2015.10

座長（Chairmanship）

第50回 九州リウマチ学会  2015.9

座長（Chairmanship）

第59回 日本リウマチ学会総会•学術集会  （ 名古屋国際会議場 ） 2015.4

座長（Chairmanship）

第49回 九州リウマチ学会  （ 福岡 ） 2015.3

座長（Chairmanship）

第42回 日本臨床免疫学会総会  （ 東京 ） 2014.9

座長（Chairmanship）

第48回 九州リウマチ学会  （ 久留米 ） 2014.9

座長（Chairmanship）

第58回 日本リウマチ学会総会•学術集会  （ 東京 ） 2014.4

座長（Chairmanship）

第46回九州リウマチ学会  （ 佐賀 ） 2013.9

座長（Chairmanship）

第57回日本リウマチ学会総会 学術集会  （ 京都 ） 2013.4

座長（Chairmanship）

第300回　日本内科学会九州地方会  2013.1

座長（Chairmanship）

第296回　日本内科学会九州地方会  （ 福岡 ） 2012.1

座長（Chairmanship）

第４１回九州リウマチ学会  （ 宮崎 ） 2011.3

座長（Chairmanship）

第３９回九州リウマチ学会  （ 福岡国際会議場 ） 2010.3

事務局

第３９回九州リウマチ学会  （ 福岡 ） 2010.3

IgG4関連疾患の病因解明と新規治療戦略 -特異なT・B細胞を標的として-

Grant number：18KK0260  2018 - 2021

日本学術振興会  科学研究費助成事業  国際共同研究強化(B)

自己免疫疾患におけるサイトカイン産生性エフェクターB細胞の役割

Grant number：18K08410  2018 - 2020

日本学術振興会  科学研究費助成事業  基盤研究(C)

ANCA関連血管炎（AAV）に対するトシリズマブの医師主導治験

2017 - 2020

科学研究費助成事業 

自己免疫疾患の病態におけるエフェクターB細胞と制御性B細胞の役割

Grant number：15K09528  2015 - 2017

日本学術振興会  科学研究費助成事業  基盤研究(C)

ヒト制御性B細胞の同定と自己免疫疾患におけるその役割

Grant number：24591450  2012 - 2015

日本学術振興会  科学研究費助成事業  基盤研究(C)

純化自己幹細胞移植術による難治性自己免疫疾患治療時の免疫再生メカニズムに関する研究

Grant number：22130801  2010 - 2012

科学研究費助成事業  厚生労働科学研究費補助金 (厚生労働省)

ヒト制御性B細胞の同定とリウマチ性疾患におけるその役割

2010

日本リウマチ財団　調査•研究助成費

ＣＢＬ会合アダプター（ＣＩＮ８５）による自己反応性Ｂ細胞の機能制御

Grant number：21591267  2009 - 2011

日本学術振興会  科学研究費助成事業  基盤研究(C)

内耳障害及び再生に関わる新規遺伝子の探索

Grant number：21592161  2009 - 2011

日本学術振興会  科学研究費助成事業  基盤研究(C)

腫瘍由来エクソゾーム中のマイクロRNAの機能解析と消化器癌診断への応用

Grant number：21590816  2009 - 2011

日本学術振興会  科学研究費助成事業  基盤研究(C)

CBL会合アダプター(CIN85)による正常ならびに自己免疫疾患B細胞の機能制御

Grant number：19591169  2007 - 2008

日本学術振興会  科学研究費助成事業  基盤研究(C)

新規アダプター分子によるB細胞機能の制御機構と自己免疫疾患におけるその役割

Grant number：17591047  2005 - 2006

日本学術振興会  科学研究費助成事業  基盤研究(C)

B細胞活性化の分子機構と自己免疫疾患におけるその制御

2004.6 - 2007.3

マクロファージ・好中球活性化の分子機構ならびに自己免疫疾患におけるその制御

1991.6 - 1998.7

臨床倫理

2022.10 - 2023.3   Second semester

基幹教育セミナー

2022.6 - 2022.8   Summer quarter

免疫学

2022.4 - 2022.9   First semester

膠原病総論

2022.4 - 2022.9   First semester

臨床倫理

2021.12 - 2022.2   Winter quarter

基幹教育セミナー

2021.6 - 2021.8   Summer quarter

膠原病総論

2021.4 - 2021.9   First semester

免疫学

2021.4 - 2021.9   First semester

内分泌代謝

2021.4 - 2021.9   First semester

臨床倫理

2020.10 - 2021.3   Second semester

臨床倫理

2020.10 - 2021.3   Second semester

ゲノム薬理学

2020.10 - 2021.3   Second semester

基幹教育セミナー

2020.6 - 2020.8   Summer quarter

免疫学

2020.4 - 2020.9   First semester

基幹教育セミナー

2020.4 - 2020.9   First semester

膠原病総論

2020.4 - 2020.9   First semester

内分泌代謝

2020.4 - 2020.9   First semester

臨床倫理

2019.10 - 2020.3   Second semester

免疫学

2019.4 - 2019.9   First semester

臨床倫理

2018.10 - 2019.3   Second semester

基幹教育セミナー

2018.6 - 2018.8   Summer quarter

免疫学

2018.4 - 2018.9   First semester

生命の科学Ａ

2018.4 - 2018.6   Spring quarter

臨床倫理

2017.10 - 2018.3   Second semester

基幹教育セミナー

2017.6 - 2017.8   Summer quarter

生命の科学A

2017.6 - 2017.8   Summer quarter

医学研究特論

2017.4 - 2017.9   First semester

膠原病総論

2017.4 - 2017.9   First semester

生命の科学A

2017.4 - 2017.6   Spring quarter

医療系統合教育

2016.10 - 2017.3   Second semester

アレルギー・膠原病、内分泌・代謝

2005.4 - 2006.3   Full year

内分泌代謝

2005.4 - 2005.9   First semester

2020.8   Role：Moderator   Title：医学科・生命科学科FD

Organizer：Undergraduate school department

2019.12   Role：Participation   Title：大学院FD

Organizer：[Undergraduate school/graduate school/graduate faculty]

2019.8   Role：Moderator   Title：医学科・生命科学科FD

Organizer：Undergraduate school department

2018.12   Role：Speech   Title：大学院FD

Organizer：[Undergraduate school/graduate school/graduate faculty]

2018.8   Role：Moderator   Title：医学科・生命科学科FD

Organizer：Undergraduate school department

2017.12   Role：Speech   Title：大学院FD

Organizer：[Undergraduate school/graduate school/graduate faculty]

2017.8   Role：Moderator   Title：医学科・生命科学科FD

Organizer：Undergraduate school department

Specialist

Japan College of Rheumatology（JCR）