Deficiency of G protein- coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein- related peptidase 4 (Klk4) during pH cycling process Invited Reviewed International journal

Chiba Y, Yoshizaki K, Sato H, Ikeuchi T, Rhodes C, Chiba M, Saito K, Nakamura T, Iwamoto T, Yamada A, Yamada Y, Fukumoto S.

FASEB JOURNAL   37 ( 4 )   2023.4

Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. Invited Reviewed International journal

Yuta T, Tian T, Chiba Y, Miyazaki K, Funada K, Mizuta K, Fu Y, Kawahara J, Iwamoto T, Takahashi I, Fukumoto S, Yoshizaki K.

Sci Rep.   2023.2

GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. Reviewed International journal

Yamada A, Yoshizaki K, Saito K, Ishikawa M, Chiba Y, Hoshikawa S, Chiba M, Hino R, Maruya Y, Sato H, Masuda K, Yamaza H, Nakamura T, Iwamoto T, Fukumoto S.

J Oral Biosci.   2022.12

Integration of Single-Cell RNA- and CAGE-seq Reveals Tooth-Enriched Genes Invited Reviewed International journal

Chiba Y, Yoshizaki K, Tian T, Miyazaki K, Martin D; Genomics and Computational Biology Core, Saito K, Yamada A, Fukumoto S.

JOURNAL OF DENTAL RESEARCH   101 ( 5 )   542 - 550   2022.5

von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation Invited Reviewed International journal

Iwata K, Kawarabayashi K, Yoshizaki K, Tian T, Saito K, Sugimoto A, Kurogoushi R, Yamada A, Yamamoto A, Kudo Y, Ishimaru N, Fukumoto S, Iwamoto T.

JOURNAL OF CELLULAR PHYSIOLOGY   237 ( 3 )   1964 - 1979   2022.3

An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. Invited Reviewed International journal

Tian T, Miyazaki K, Chiba Y, Funada K, Yuta T, Mizuta K, Fu Y, Kawahara J, Han X, Ando Y, Funada A, Yamada A, Iwamoto T, Nakamura S, Takahashi I, Fukumoto S, Yoshizaki K.

Scientific reports   12 ( 1 )   3093 - 3093   2022.2

The tooth-specific basic helix-loop-helix factor AmeloD promotes differentiation of ameloblasts Invited Reviewed International journal

Jia L, Chiba Y, Saito K, Yoshizaki K, Tian T, Han X, Mizuta K, Chiba M, Wang X, Al Thamin S, Yamada A, Fukumoto S.

JOURNAL OF CELLULAR PHYSIOLOGY   237 ( 2 )   1597 - 1606   2022.2

Deletion of epithelial cell-specific p130Cas impairs the maturation stage of amelogenesis Invited Reviewed International journal

Inoue A, Kiyoshima T, Yoshizaki K, Nakatomi C, Nakatomi M, Ohshima H, Shin M, Gao J, Tsuru K, Okabe K, Nakamura I, Honda H, Matsuda M, Takahashi I, Jimi E.

BONE   154   2022.1

Transcriptional regulation of the basic helix-loop-helix factor AmeloD during tooth development Invited Reviewed International journal

Al Thamin S, Chiba Y, Yoshizaki K, Tian T, Jia L, Wang X, Saito K, Li J, Yamada A, Fukumoto S.

JOURNAL OF CELLULAR PHYSIOLOGY   236 ( 11 )   7533 - 7543   2021.11

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation Invited Reviewed International journal

Yamada A, Yoshizaki K, Ishikawa M, Saito K, Chiba Y, Fukumoto E, Hino R, Hoshikawa S, Chiba M, Nakamura T, Iwamoto T, Fukumoto S.

FRONTIERS IN PHYSIOLOGY   12   2021.9

Characteristics of craniofacial morphology and factors affecting them in patients with isolated cleft palate Invited Reviewed International journal

Tsuji K, Haruyama N, Nomura S, Murata N, Yoshizaki K, Mitsuyasu T, Nakano H, Nakamura S, Mori Y, Takahashi I.

PEERJ   9   2021.4

Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation Invited Reviewed International journal

Hino R, Yamada A, Chiba Y, Yoshizaki K, Fukumoto E, Iwamoto T, Maruya Y, Otsu K, Harada H, Saito K, Fukumoto S.

Pediatric Dental Journal   30 ( 3 )   208 - 214   2020.12

Transcriptional Regulation of Dental Epithelial Cell Fate Invited Reviewed International journal

Yoshizaki K, Fukumoto S, Bikle DD, Oda Y.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   21 ( 23 )   2020.12

G protein-coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts Invited Reviewed International journal

Chiba Y, Yoshizaki K, Saito K, Ikeuchi T, Iwamoto T, Rhodes C, Nakamura T, de Vega S, Morell RJ, Boger ET, Martin D, Hino R, Inuzuka H, Bleck CKE, Yamada A, Yamada Y, Fukumoto S.

JOURNAL OF BIOLOGICAL CHEMISTRY   295 ( 45 )   15328 - 15341   2020.11

Expression Patterns of Claudin Family Members During Tooth Development and the Role of Claudin-10 (Cldn10) in Cytodifferentiation of Stratum Intermedium Invited Reviewed International journal

Wang X, Chiba Y, Jia L, Yoshizaki K, Saito K, Yamada A, Qin M, Fukumoto S.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY   8   2020.10

Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes Invited Reviewed International journal

Chiba Y, Saito K, Martin D, Boger ET, Rhodes C, Yoshizaki K, Nakamura T, Yamada A, Morell RJ, Yamada Y, Fukumoto S.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY   8   2020.9

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ Invited Reviewed International journal

Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S.

ISCIENCE   23 ( 7 )   2020.7

microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Reviewed International journal

Funada K, Yoshizaki K, MIyazaki K, Han X, Yuta T, Tian T, Mizuta K, Fu Y, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.

Scientific Reports   2020.3

Mouse embryonic tooth germ dissection and ex vivo culture protocol. Invited Reviewed International journal

Han X, Yoshizaki K, Tian T, Miyazaki K, Takahashi I, Fukumoto S.

Bio-protocol   2020.2

Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1. Reviewed International journal

Miyazaki A, Sugimoto A, Yoshizaki K, Kawarabayashi K, Iwata K, Kurogoushi R, Kitamura T, Otsuka K, Hasegawa T, Akazawa Y, Fukumoto S, Ishimaru N, Iwamoto T

Scientific Reports   2019.10

The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology Invited Reviewed International journal

Chiba Y, He B, Yoshizaki K, Rhodes C, Ishijima M, Bleck CKE, Stempinski E, Chu EY, Nakamura T, Iwamoto T, de Vega S, Saito K, Fukumoto S, Yamada Y.

JOURNAL OF BIOLOGICAL CHEMISTRY   294 ( 10 )   3406 - 3418   2019.3

Identification of the Novel Tooth-Specific Transcription Factor AmeloD Invited Reviewed International journal

He B, Chiba Y, Li H, de Vega S, Tanaka K, Yoshizaki K, Ishijima M, Yuasa K, Ishikawa M, Rhodes C, Sakai K, Zhang P, Fukumoto S, Zhou X, Yamada Y.

JOURNAL OF DENTAL RESEARCH   98 ( 2 )   234 - 241   2019.2

The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development Reviewed International journal

Han X, Yoshizaki K, Miyazaki K, Arai C, Funada K, Yuta T, Tian T, Chiba Y, Saito K, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.

JOURNAL OF BIOLOGICAL CHEMISTRY   293 ( 38 )   14572 - 14584   2018.9

Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells Invited Reviewed International journal

Sugimoto A, Miyazaki A, Kawarabayashi K, Shono M, Akazawa Y, Hasegawa T, Ueda-Yamaguchi K, Kitamura T, Yoshizaki K, Fukumoto S, Iwamoto T.

SCIENTIFIC REPORTS   7   2017.12

Stim1 Regulates Enamel Mineralization and Ameloblast Modulation Invited Reviewed International journal

Furukawa Y, Haruyama N, Nikaido M, Nakanishi M, Ryu N, Oh-Hora M, Kuremoto K, Yoshizaki K, Takano Y, Takahashi I.

JOURNAL OF DENTAL RESEARCH   96 ( 12 )   1422 - 1429   2017.11

Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene Invited Reviewed International journal

Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, Den Besten P, Bikle DD, Oda Y, Yamada Y.

JOURNAL OF BIOLOGICAL CHEMISTRY   292 ( 33 )   13531 - 13540   2017.8

Pannexin 3 regulates proliferation and differentiation of odontoblasts via its hemichannel activities Invited Reviewed International journal

Iwamoto T, Nakamura T, Ishikawa M, Yoshizaki K, Sugimoto A, Ida-Yonemochi H, Ohshima H, Saito M, Yamada Y, Fukumoto S

PLOS ONE   12 ( 5 )   2017.5

A Longitudinal Study of the Presence of Dental Anomalies in the Primary and Permanent Dentitions of Cleft Lip and/or Palate Patients. Invited Reviewed International journal

Suzuki A, Nakano M, Yoshizaki K, Yasunaga A, Haruyama N, Ichiro Takahashi

Cleft Palate Craniofac J   2017.5

Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains Invited Reviewed International journal

SCIENTIFIC REPORTS   7   2017.3

口唇裂口蓋裂患者の矯正歯科受診と咬合の実態　–九州大学病院矯正歯科における43年 間の臨床統計− Invited Reviewed International journal

祐田 京子, 丸山　和宏, 鈴木 陽, 安永　敦, 下村　卓弘, 吉﨑 恵悟, 春山 直人, 髙橋 一郎

日本口蓋裂学会雑誌   41 ( 3 )   192 - 200   2016.10

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation. Reviewed International journal

Liu J, Saito K, Maruya Y, Nakamura T, Yamada A, Fukumoto E, Ishikawa M, Iwamoto T, Miyazaki K, Yoshizaki K, Ge L, Fukumoto S

Sci Rep.   2016.3

Plakophilin-1, a Novel Wnt Signaling Regulator, Is Critical for Tooth Development and Ameloblast Differentiation. Reviewed International journal

Miyazaki K, Yoshizaki K, Arai C, Yamada A, Saito K, Ishikawa M, Xue H, Funada K, Haruyama N, Yamada Y, Fukumoto S, Ichiro Takahashi

PLoS One.   11 ( 3 )   e0152206.   2016.3

Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. Reviewed International journal

Yamada A, Futagi M, Fukumoto E, Saito K, Yoshizaki K, Ishikawa M, Arakaki M, Hino R, Sugawara Y, Ishikawa M, Naruse M, Miyazaki K, Nakamura T, Fukumoto S

291 ( 2 )   904 - 912   2016.1

MicroRNA-200a Regulates the Development of Mandibular Condylar Cartilage. Reviewed International journal

Umeda M, Fumie TERAO, Miyazaki K, Yoshizaki K, Ichiro Takahashi

J Dent Res.   94 ( 6 )   795 - 802   2015.6

Interaction between Fibronectin and beta 1 Integrin Is Essential for Tooth Development

Saito K, Fukumoto E, Yamada A, Yuasa K, Yoshizaki K, Iwamoto T, Saito M, Nakamura T, Fukumoto S

PLOS ONE   10 ( 4 )   2015.4

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair Reviewed International journal

Keigo Yoshizaki, Lizhi Hu, Thai Nguyen, Kiyoshi Sakai, Bing He, Chak Fong, Yoshihiko Yamada, , Daniel D. Bikle, Yuko Oda

PLOS ONE   9 ( 6 )   e9991   2014.6

Tenurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS International journal

Suzuki N, Fukushi M, Kosaki K, Doyle AD, de Vega S, Keigo Yoshizaki, Akazawa C, Arikawa-Hirasawa E, Yamada Y

J Neurosci.   32 ( 34 )   11586 - 11599   2012.8

Glycosphingolipids Regulate Ameloblastin Expression in Dental Epithelial Cells

Kamasaki, Y., Nakamura, T., Keigo Yoshizaki, Iwamoto, T., aya yamada, Fukumoto, E., Maruya, Y., Iwabuchi, K., Furukawa, K., Fujiwara, T., Satoshi Fukumoto

JOURNAL OF DENTAL RESEARCH   91 ( 1 )   2012.1

Sprouty2 controls proliferation of palate mesenchymal cells via fibroblast growth factor signaling

Matsumura, Kaori, Taketomi, Takaharu, Keigo Yoshizaki, Arai, Shinsaku, Sanui, Terukazu, Yoshiga, Daigo, Yoshimura, Akihiko, Nakamura, Seiji

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   404 ( 4 )   2011.1

PDGFs regulate tooth germ proliferation and ameloblast differentiation

Wu, Nan, Iwamoto, Tsutomu, Sugawara, Yu, Futaki, Masaharu, Keigo Yoshizaki, Yamamoto, Shinya, aya yamada, Nakamura, Takashi, Kazuaki Nonaka, Satoshi Fukumoto

ARCHIVES OF ORAL BIOLOGY   55 ( 6 )   2010.6

Connexin43 plays an important role in lung development

Nagata, Kouji, Masumoto, Kouji, Esumi, Genshirou, Teshiba, Risa, Keigo Yoshizaki, Satoshi Fukumoto, Kazuaki Nonaka, Taguchi, Tomoaki

JOURNAL OF PEDIATRIC SURGERY   44 ( 12 )   2009.12

Critical Role of Heparin Binding Domains of Ameloblastin for Dental Epithelium Cell Adhesion and Ameloblastoma Proliferation

Sonoda, Akira, Iwamoto, Tsutomu;, Nakamura, Takashi, Fukumoto, Emiko, Keigo Yoshizaki, aya yamada, Arakaki, Makiko, Harada, Hidemitsu, Kazuaki Nonaka, Seiji Nakamura, Yamada, Yoshihiko, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   284 ( 40 )   2009.10

Prevalence of Natal/Neonatal Teeth in Cleft Lip and Palate Infants

Iwamoto T, Keigo Yoshizaki, Sonoda A, Nakamura Y, Matsuishi Y, Yamaguchi N, Kazuaki Nonaka

PEDIATRIC DENTAL JOURNAL   2009.1

Dens evaginatus and dens invaginatus in a mandibular central incisor

Iwamoto T, Keigo Yoshizaki, Yuki Nakamura, Sonoda A, Nakamoto Y, Yukiko Okuma, Tamiya R, Kazuaki Nonaka

PEDIATRIC DENTAL JOURNAL   2009.1

Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression

Yamamoto, Shinya, Fukumoto, Emiko, Keigo Yoshizaki, Fukumoto, Emiko, aya yamada, Tanaka, Kojiro, Suzuki, Hiroharu, Aizawa, Shizuko, Arakaki, Makiko, Yuasa, Kenji, Oka, Kyoko, Chai, Yang, Kazuaki Nonaka, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   283 ( 34 )   2008.8

Neurotrophic factor neurotrophin-4 regulates ameloblastin expression via full-length TrkB

Keigo Yoshizaki, Yamamoto, Shinya, aya yamada, Yuasa, Kenji, Iwamoto, Tsutomu, Fukumoto, Emiko, Harada, Hidemitsu, Saito, Masahiro, Akihiko Nakasima, Nonaka, Kazuaki, Yamada, Yoshihiko, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   283 ( 6 )   2008.2

Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice

Nagata Kouji, Masumoto Kouji, Uesugi Toru, Yamamoto Shinya, Keigo Yoshizaki, Satoshi Fukumoto, Kazuaki Nonaka, Taguchi Tomoaki

PEDIATRIC SURGERY INTERNATIONAL   23 ( 10 )   2007.10

Retrospective evaluation of treatment outcome in Japanese children with complete unilateral cleft lip and palate. Part 1: Five-year-olds' index for dental arch relationships

Suzuki Akira, Keigo Yoshizaki, Honda Yasuo, Sasaguri Masaaki, Kubota Yasutaka, Nakamura Norifumi, Ohishi Masamichi, Oka Masuichiro, Tashiro Hideo, Katsuki Takeshi, Fujino Hiroshi

CLEFT PALATE-CRANIOFACIAL JOURNAL   44 ( 4 )   2007.7

Amelogenin is a negative regulator of osteoclastogenesis via down-regulation of RANKL, M-CSF and expression in osteoblasts.

Nishiguchi M, Yuasa K, Saito K, Fukumoto E, aya yamada, Hasegawa T, Keigo Yoshizaki, Kamasaki Y, Kazuaki Nonaka, Fujiwara T, Satoshi Fukumoto

Arch Oral Biol.   2007.3

TGF-beta 3 induces ectopic mineralization in fetal mouse dental pulp during tooth germ development

Huojia, M, Muraoka, N, Keigo Yoshizaki, Satoshi Fukumoto, MISAKO NAKASHIMA, Akifumi Akamine, Kazuaki Nonaka, Ohishi, M

DEVELOPMENT GROWTH & DIFFERENTIATION   47 ( 3 )   2005.4

日本顎変形症学会