Deficiency of G protein- coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein- related peptidase 4 (Klk4) during pH cycling process 招待 査読 国際誌

Chiba Y, Yoshizaki K, Sato H, Ikeuchi T, Rhodes C, Chiba M, Saito K, Nakamura T, Iwamoto T, Yamada A, Yamada Y, Fukumoto S.

FASEB JOURNAL   37 ( 4 )   2023年4月

Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues. 招待 査読 国際誌

Yuta T, Tian T, Chiba Y, Miyazaki K, Funada K, Mizuta K, Fu Y, Kawahara J, Iwamoto T, Takahashi I, Fukumoto S, Yoshizaki K.

Sci Rep.   2023年2月

GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. 査読 国際誌

Yamada A, Yoshizaki K, Saito K, Ishikawa M, Chiba Y, Hoshikawa S, Chiba M, Hino R, Maruya Y, Sato H, Masuda K, Yamaza H, Nakamura T, Iwamoto T, Fukumoto S.

J Oral Biosci.   2022年12月

Integration of Single-Cell RNA- and CAGE-seq Reveals Tooth-Enriched Genes 招待 査読 国際誌

Chiba Y, Yoshizaki K, Tian T, Miyazaki K, Martin D; Genomics and Computational Biology Core, Saito K, Yamada A, Fukumoto S.

JOURNAL OF DENTAL RESEARCH   101 ( 5 )   542 - 550   2022年5月

von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation 招待 査読 国際誌

Iwata K, Kawarabayashi K, Yoshizaki K, Tian T, Saito K, Sugimoto A, Kurogoushi R, Yamada A, Yamamoto A, Kudo Y, Ishimaru N, Fukumoto S, Iwamoto T.

JOURNAL OF CELLULAR PHYSIOLOGY   237 ( 3 )   1964 - 1979   2022年3月

An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs. 招待 査読 国際誌

Tian T, Miyazaki K, Chiba Y, Funada K, Yuta T, Mizuta K, Fu Y, Kawahara J, Han X, Ando Y, Funada A, Yamada A, Iwamoto T, Nakamura S, Takahashi I, Fukumoto S, Yoshizaki K.

Scientific reports   12 ( 1 )   3093 - 3093   2022年2月

The tooth-specific basic helix-loop-helix factor AmeloD promotes differentiation of ameloblasts 招待 査読 国際誌

Jia L, Chiba Y, Saito K, Yoshizaki K, Tian T, Han X, Mizuta K, Chiba M, Wang X, Al Thamin S, Yamada A, Fukumoto S.

JOURNAL OF CELLULAR PHYSIOLOGY   237 ( 2 )   1597 - 1606   2022年2月

Deletion of epithelial cell-specific p130Cas impairs the maturation stage of amelogenesis 招待 査読 国際誌

Inoue A, Kiyoshima T, Yoshizaki K, Nakatomi C, Nakatomi M, Ohshima H, Shin M, Gao J, Tsuru K, Okabe K, Nakamura I, Honda H, Matsuda M, Takahashi I, Jimi E.

BONE   154   2022年1月

Transcriptional regulation of the basic helix-loop-helix factor AmeloD during tooth development 招待 査読 国際誌

Al Thamin S, Chiba Y, Yoshizaki K, Tian T, Jia L, Wang X, Saito K, Li J, Yamada A, Fukumoto S.

JOURNAL OF CELLULAR PHYSIOLOGY   236 ( 11 )   7533 - 7543   2021年11月

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation 招待 査読 国際誌

Yamada A, Yoshizaki K, Ishikawa M, Saito K, Chiba Y, Fukumoto E, Hino R, Hoshikawa S, Chiba M, Nakamura T, Iwamoto T, Fukumoto S.

FRONTIERS IN PHYSIOLOGY   12   2021年9月

Characteristics of craniofacial morphology and factors affecting them in patients with isolated cleft palate 招待 査読 国際誌

Tsuji K, Haruyama N, Nomura S, Murata N, Yoshizaki K, Mitsuyasu T, Nakano H, Nakamura S, Mori Y, Takahashi I.

PEERJ   9   2021年4月

Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation 招待 査読 国際誌

Hino R, Yamada A, Chiba Y, Yoshizaki K, Fukumoto E, Iwamoto T, Maruya Y, Otsu K, Harada H, Saito K, Fukumoto S.

Pediatric Dental Journal   30 ( 3 )   208 - 214   2020年12月

Transcriptional Regulation of Dental Epithelial Cell Fate 招待 査読 国際誌

Yoshizaki K, Fukumoto S, Bikle DD, Oda Y.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   21 ( 23 )   2020年12月

G protein-coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts 招待 査読 国際誌

Chiba Y, Yoshizaki K, Saito K, Ikeuchi T, Iwamoto T, Rhodes C, Nakamura T, de Vega S, Morell RJ, Boger ET, Martin D, Hino R, Inuzuka H, Bleck CKE, Yamada A, Yamada Y, Fukumoto S.

JOURNAL OF BIOLOGICAL CHEMISTRY   295 ( 45 )   15328 - 15341   2020年11月

Expression Patterns of Claudin Family Members During Tooth Development and the Role of Claudin-10 (Cldn10) in Cytodifferentiation of Stratum Intermedium 招待 査読 国際誌

Wang X, Chiba Y, Jia L, Yoshizaki K, Saito K, Yamada A, Qin M, Fukumoto S.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY   8   2020年10月

Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes 招待 査読 国際誌

Chiba Y, Saito K, Martin D, Boger ET, Rhodes C, Yoshizaki K, Nakamura T, Yamada A, Morell RJ, Yamada Y, Fukumoto S.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY   8   2020年9月

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ 招待 査読 国際誌

Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S.

ISCIENCE   23 ( 7 )   2020年7月

microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. 査読 国際誌

Funada K, Yoshizaki K, MIyazaki K, Han X, Yuta T, Tian T, Mizuta K, Fu Y, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.

Scientific Reports   2020年3月

Mouse embryonic tooth germ dissection and ex vivo culture protocol. 招待 査読 国際誌

Han X, Yoshizaki K, Tian T, Miyazaki K, Takahashi I, Fukumoto S.

Bio-protocol   2020年2月

Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1. 査読 国際誌

Miyazaki A, Sugimoto A, Yoshizaki K, Kawarabayashi K, Iwata K, Kurogoushi R, Kitamura T, Otsuka K, Hasegawa T, Akazawa Y, Fukumoto S, Ishimaru N, Iwamoto T

Scientific Reports   2019年10月

The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology 招待 査読 国際誌

Chiba Y, He B, Yoshizaki K, Rhodes C, Ishijima M, Bleck CKE, Stempinski E, Chu EY, Nakamura T, Iwamoto T, de Vega S, Saito K, Fukumoto S, Yamada Y.

JOURNAL OF BIOLOGICAL CHEMISTRY   294 ( 10 )   3406 - 3418   2019年3月

Identification of the Novel Tooth-Specific Transcription Factor AmeloD 招待 査読 国際誌

He B, Chiba Y, Li H, de Vega S, Tanaka K, Yoshizaki K, Ishijima M, Yuasa K, Ishikawa M, Rhodes C, Sakai K, Zhang P, Fukumoto S, Zhou X, Yamada Y.

JOURNAL OF DENTAL RESEARCH   98 ( 2 )   234 - 241   2019年2月

The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development 査読 国際誌

Han X, Yoshizaki K, Miyazaki K, Arai C, Funada K, Yuta T, Tian T, Chiba Y, Saito K, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.

JOURNAL OF BIOLOGICAL CHEMISTRY   293 ( 38 )   14572 - 14584   2018年9月

Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells 招待 査読 国際誌

Sugimoto A, Miyazaki A, Kawarabayashi K, Shono M, Akazawa Y, Hasegawa T, Ueda-Yamaguchi K, Kitamura T, Yoshizaki K, Fukumoto S, Iwamoto T.

SCIENTIFIC REPORTS   7   2017年12月

Stim1 Regulates Enamel Mineralization and Ameloblast Modulation 招待 査読 国際誌

Furukawa Y, Haruyama N, Nikaido M, Nakanishi M, Ryu N, Oh-Hora M, Kuremoto K, Yoshizaki K, Takano Y, Takahashi I.

JOURNAL OF DENTAL RESEARCH   96 ( 12 )   1422 - 1429   2017年11月

Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene 招待 査読 国際誌

Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, Den Besten P, Bikle DD, Oda Y, Yamada Y.

JOURNAL OF BIOLOGICAL CHEMISTRY   292 ( 33 )   13531 - 13540   2017年8月

Pannexin 3 regulates proliferation and differentiation of odontoblasts via its hemichannel activities 招待 査読 国際誌

Iwamoto T, Nakamura T, Ishikawa M, Yoshizaki K, Sugimoto A, Ida-Yonemochi H, Ohshima H, Saito M, Yamada Y, Fukumoto S

PLOS ONE   12 ( 5 )   2017年5月

A Longitudinal Study of the Presence of Dental Anomalies in the Primary and Permanent Dentitions of Cleft Lip and/or Palate Patients. 招待 査読 国際誌

Suzuki A, Nakano M, Yoshizaki K, Yasunaga A, Haruyama N, Ichiro Takahashi

Cleft Palate Craniofac J   2017年5月

Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains 招待 査読 国際誌

SCIENTIFIC REPORTS   7   2017年3月

口唇裂口蓋裂患者の矯正歯科受診と咬合の実態　–九州大学病院矯正歯科における43年 間の臨床統計− 招待 査読 国際誌

祐田 京子, 丸山　和宏, 鈴木 陽, 安永　敦, 下村　卓弘, 吉﨑 恵悟, 春山 直人, 髙橋 一郎

日本口蓋裂学会雑誌   41 ( 3 )   192 - 200   2016年10月

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation. 査読 国際誌

Liu J, Saito K, Maruya Y, Nakamura T, Yamada A, Fukumoto E, Ishikawa M, Iwamoto T, Miyazaki K, Yoshizaki K, Ge L, Fukumoto S

Sci Rep.   2016年3月

Plakophilin-1, a Novel Wnt Signaling Regulator, Is Critical for Tooth Development and Ameloblast Differentiation. 査読 国際誌

Miyazaki K, Yoshizaki K, Arai C, Yamada A, Saito K, Ishikawa M, Xue H, Funada K, Haruyama N, Yamada Y, Fukumoto S, Ichiro Takahashi

PLoS One.   11 ( 3 )   e0152206.   2016年3月

Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. 査読 国際誌

Yamada A, Futagi M, Fukumoto E, Saito K, Yoshizaki K, Ishikawa M, Arakaki M, Hino R, Sugawara Y, Ishikawa M, Naruse M, Miyazaki K, Nakamura T, Fukumoto S

291 ( 2 )   904 - 912   2016年1月

MicroRNA-200a Regulates the Development of Mandibular Condylar Cartilage. 査読 国際誌

Umeda M, Fumie TERAO, Miyazaki K, Yoshizaki K, Ichiro Takahashi

J Dent Res.   94 ( 6 )   795 - 802   2015年6月

Interaction between Fibronectin and beta 1 Integrin Is Essential for Tooth Development

Saito K, Fukumoto E, Yamada A, Yuasa K, Yoshizaki K, Iwamoto T, Saito M, Nakamura T, Fukumoto S

PLOS ONE   10 ( 4 )   2015年4月

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair 査読 国際誌

Keigo Yoshizaki, Lizhi Hu, Thai Nguyen, Kiyoshi Sakai, Bing He, Chak Fong, Yoshihiko Yamada, , Daniel D. Bikle, Yuko Oda

PLOS ONE   9 ( 6 )   e9991   2014年6月

Tenurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS 国際誌

Suzuki N, Fukushi M, Kosaki K, Doyle AD, de Vega S, Keigo Yoshizaki, Akazawa C, Arikawa-Hirasawa E, Yamada Y

J Neurosci.   32 ( 34 )   11586 - 11599   2012年8月

Glycosphingolipids Regulate Ameloblastin Expression in Dental Epithelial Cells

Kamasaki, Y., Nakamura, T., Keigo Yoshizaki, Iwamoto, T., aya yamada, Fukumoto, E., Maruya, Y., Iwabuchi, K., Furukawa, K., Fujiwara, T., Satoshi Fukumoto

JOURNAL OF DENTAL RESEARCH   91 ( 1 )   2012年1月

Sprouty2 controls proliferation of palate mesenchymal cells via fibroblast growth factor signaling

Matsumura, Kaori, Taketomi, Takaharu, Keigo Yoshizaki, Arai, Shinsaku, Sanui, Terukazu, Yoshiga, Daigo, Yoshimura, Akihiko, Nakamura, Seiji

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   404 ( 4 )   2011年1月

PDGFs regulate tooth germ proliferation and ameloblast differentiation

Wu, Nan, Iwamoto, Tsutomu, Sugawara, Yu, Futaki, Masaharu, Keigo Yoshizaki, Yamamoto, Shinya, aya yamada, Nakamura, Takashi, Kazuaki Nonaka, Satoshi Fukumoto

ARCHIVES OF ORAL BIOLOGY   55 ( 6 )   2010年6月

Connexin43 plays an important role in lung development

Nagata, Kouji, Masumoto, Kouji, Esumi, Genshirou, Teshiba, Risa, Keigo Yoshizaki, Satoshi Fukumoto, Kazuaki Nonaka, Taguchi, Tomoaki

JOURNAL OF PEDIATRIC SURGERY   44 ( 12 )   2009年12月

Critical Role of Heparin Binding Domains of Ameloblastin for Dental Epithelium Cell Adhesion and Ameloblastoma Proliferation

Sonoda, Akira, Iwamoto, Tsutomu;, Nakamura, Takashi, Fukumoto, Emiko, Keigo Yoshizaki, aya yamada, Arakaki, Makiko, Harada, Hidemitsu, Kazuaki Nonaka, Seiji Nakamura, Yamada, Yoshihiko, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   284 ( 40 )   2009年10月

Prevalence of Natal/Neonatal Teeth in Cleft Lip and Palate Infants

Iwamoto T, Keigo Yoshizaki, Sonoda A, Nakamura Y, Matsuishi Y, Yamaguchi N, Kazuaki Nonaka

PEDIATRIC DENTAL JOURNAL   2009年1月

Dens evaginatus and dens invaginatus in a mandibular central incisor

Iwamoto T, Keigo Yoshizaki, Yuki Nakamura, Sonoda A, Nakamoto Y, Yukiko Okuma, Tamiya R, Kazuaki Nonaka

PEDIATRIC DENTAL JOURNAL   2009年1月

Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression

Yamamoto, Shinya, Fukumoto, Emiko, Keigo Yoshizaki, Fukumoto, Emiko, aya yamada, Tanaka, Kojiro, Suzuki, Hiroharu, Aizawa, Shizuko, Arakaki, Makiko, Yuasa, Kenji, Oka, Kyoko, Chai, Yang, Kazuaki Nonaka, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   283 ( 34 )   2008年8月

Neurotrophic factor neurotrophin-4 regulates ameloblastin expression via full-length TrkB

Keigo Yoshizaki, Yamamoto, Shinya, aya yamada, Yuasa, Kenji, Iwamoto, Tsutomu, Fukumoto, Emiko, Harada, Hidemitsu, Saito, Masahiro, Akihiko Nakasima, Nonaka, Kazuaki, Yamada, Yoshihiko, Satoshi Fukumoto

JOURNAL OF BIOLOGICAL CHEMISTRY   283 ( 6 )   2008年2月

Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice

Nagata Kouji, Masumoto Kouji, Uesugi Toru, Yamamoto Shinya, Keigo Yoshizaki, Satoshi Fukumoto, Kazuaki Nonaka, Taguchi Tomoaki

PEDIATRIC SURGERY INTERNATIONAL   23 ( 10 )   2007年10月

Retrospective evaluation of treatment outcome in Japanese children with complete unilateral cleft lip and palate. Part 1: Five-year-olds' index for dental arch relationships

Suzuki Akira, Keigo Yoshizaki, Honda Yasuo, Sasaguri Masaaki, Kubota Yasutaka, Nakamura Norifumi, Ohishi Masamichi, Oka Masuichiro, Tashiro Hideo, Katsuki Takeshi, Fujino Hiroshi

CLEFT PALATE-CRANIOFACIAL JOURNAL   44 ( 4 )   2007年7月

Amelogenin is a negative regulator of osteoclastogenesis via down-regulation of RANKL, M-CSF and expression in osteoblasts.

Nishiguchi M, Yuasa K, Saito K, Fukumoto E, aya yamada, Hasegawa T, Keigo Yoshizaki, Kamasaki Y, Kazuaki Nonaka, Fujiwara T, Satoshi Fukumoto

Arch Oral Biol.   2007年3月

TGF-beta 3 induces ectopic mineralization in fetal mouse dental pulp during tooth germ development

Huojia, M, Muraoka, N, Keigo Yoshizaki, Satoshi Fukumoto, MISAKO NAKASHIMA, Akifumi Akamine, Kazuaki Nonaka, Ohishi, M

DEVELOPMENT GROWTH & DIFFERENTIATION   47 ( 3 )   2005年4月

日本顎変形症学会