Updated on 2024/07/30

Information

 

写真a

 
SHIRAISHI MIYAKO
 
Organization
Faculty of Pharmaceutical Sciences Department of Pharmaceutical Health Care and Sciences Assistant Professor
Title
Assistant Professor

Degree

  • PhD in Agriculture

Research History

  • Osaka University

Awards

  • 九州大学学生表彰受賞

    2017.3  

  • 平成28年度生物資源環境科学府賞

    2017.3  

  • 平成28年度日本農芸化学会西日本支部奨励賞(学生)

    2017.1  

  • The International Society for Extremophiles Poster Award

    2016.9   The International Society for Extremophiles   The International Society for Extremophiles Poster Award

  • 2013年日本蛋白質科学会 若手ポスター賞

    2013.6   日本蛋白質科学会  

Papers

  • Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis. Reviewed International journal

    Corina N D'Alessandro-Gabazza, Taro Yasuma, Tetsu Kobayashi, Masaaki Toda, Ahmed M Abdel-Hamid, Hajime Fujimoto, Osamu Hataji, Hiroki Nakahara, Atsuro Takeshita, Kota Nishihama, Tomohito Okano, Haruko Saiki, Yuko Okano, Atsushi Tomaru, Valeria Fridman D'Alessandro, Miyako Shiraishi, Akira Mizoguchi, Ryoichi Ono, Junpei Ohtsuka, Masayuki Fukumura, Tetsuya Nosaka, Xuenan Mi, Diwakar Shukla, Kensuke Kataoka, Yasuhiro Kondoh, Masaki Hirose, Toru Arai, Yoshikazu Inoue, Yutaka Yano, Roderick I Mackie, Isaac Cann, Esteban C Gabazza

    Nature communications   13 ( 1 )   1558 - 1558   2022.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-022-29064-3

  • Endonuclease V from the archaeon Thermococcus kodakarensis is an inosine-specific ribonuclease. Reviewed International journal

    Miyako Shiraishi, Michihi Hidaka, Shigenori Iwai

    Bioscience, biotechnology, and biochemistry   2021.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/bbb/zbab219

  • Mutational analysis of Thermococcus kodakarensis endonuclease III reveals the roles of evolutionarily conserved residues Reviewed

    Miyako Shiraishi, Kento Mizutani, Junpei Yamamoto, Shigenori Iwai

    DNA Repair   90   102859   2020.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Repository Public URL: https://hdl.handle.net/2324/7183346

  • Development CRISPR-Cas12-based rapid EGFR mutation detection kit.

    Kei Kunimasa, Yuya Bando, Miyako Shiraishi, Emi Aizawa, Kazumi Nishino, Motohiro Tamiya, Takoko Inoue, Hanako Kuhara, Hayato Kawachi, Kika Kuno, Fumio Imamura, Shigenori Iwai, Toru Kumagai, Keiichiro SUzuki

    JOURNAL OF CLINICAL ONCOLOGY   38 ( 15 )   2020.5

     More details

    Language:English  

  • Molecular Basis of Substrate Recognition of Endonuclease Q from the Euryarchaeon Pyrococcus furiosus. Reviewed

    Shiraishi M, Iwai S

    Journal of bacteriology   202 ( 2 )   2020.1

     More details

    Language:Others  

    Molecular Basis of Substrate Recognition of Endonuclease Q from the Euryarchaeon Pyrococcus furiosus.

    DOI: 10.1128/JB.00542-19

  • The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG. Reviewed

    Shiraishi M, Ishino S, Heffernan M, Cann I, Ishino Y

    Scientific reports   8 ( 1 )   15791   2018.10

     More details

    Language:Others  

    The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG.

    DOI: 10.1038/s41598-018-34000-x

  • Fluorescence detection of DNA mismatch repair in human cells. Reviewed

    Ito S, Shiraishi M, Tsuchihashi K, Takatsuka R, Yamamoto J, Kuraoka I, Iwai S

    Scientific reports   8 ( 1 )   12181   2018.8

     More details

    Language:Others  

    Fluorescence detection of DNA mismatch repair in human cells.

    DOI: 10.1038/s41598-018-30733-x

  • A functional endonuclease Q exists in the bacterial domain: identification and characterization of endonuclease Q from Bacillus pumilus Reviewed

    Miyako Shiraishi, Sonoko Ishino, Isaac Cann, Yoshizumi Ishino

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   81 ( 5 )   931 - 937   2017.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/09168451.2016.1277946

  • PCNA is involved in the EndoQ-mediated DNA repair process in Thermococcales Reviewed

    Miyako Shiraishi, Sonoko Ishino, Kotaro Yoshida, Takeshi Yamagami, Isaac Cann, Yoshizumi Ishino

    SCIENTIFIC REPORTS   6   25532   2016.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/srep25532

  • EndoQ and EndoV work individually for damaged DNA base repair in Pyrococcus furiosus Reviewed

    Sonoko Ishino, Naruto Makita, Miyako Shiraishi, Takeshi Yamagami, Yoshizumi Ishino

    BIOCHIMIE   118   264 - 269   2015.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.biochi.2015.06.015

  • A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus Reviewed

    Miyako Shiraishi, Sonoko Ishino, Takeshi Yamagami, Yuriko Egashira, Shinichi Kiyonari, Yoshizumi Ishino

    NUCLEIC ACIDS RESEARCH   43 ( 5 )   2853 - 2863   2015.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/nar/gkv121

    Repository Public URL: https://hdl.handle.net/2324/7183344

▼display all

Presentations

  • 古細菌群に保存される真核生物型ヌクレオチド除去修復因子XPBの機能解析

    玉村百香, 白石都, 岩井成憲

    第46回日本分子生物学会年会  2023.12 

     More details

    Language:Others  

    Country:Other  

  • アーキアの損傷塩基除去修復に関わる新規酵素の発見

    白石 都, 石野園子, 牧田成人, 江頭由里子, 清成信一, 山上 健, 石野良純

    日本生化学会 九州支部例会  2013.5 

     More details

    Language:Japanese  

    Country:Other  

  • 超好熱性アーキアPyrococcus furiosusから同定された新規な修復エンドヌクレアーゼ

    白石 都, 石野園子, 牧田成人, 江頭由里子, 清成信一, 山上 健, 石野良純

    第13回 日本蛋白質科学会年会  2013.6 

     More details

    Language:English  

    Country:Other  

  • アーキアに見出された損傷塩基修復酵素Endonuclease Qの特性

    白石 都, 石野園子, 牧田成人, 江頭由里子, 清成信一, 山上 健, 石野良純

    第26回日本Archaea研究会  2013.7 

     More details

    Language:Japanese  

    Country:Other  

  • A novel endonuclease responsible for damaged DNA repair in archaeal order Thermococcales

    Shiraishi, M, Ishono, S, Egashira, Y, Kiyonari, S, Yamagami, T, Cann, I, Ishino, Y

    2016.3 

     More details

    Language:English  

    Country:Other  

    A novel endonuclease responsible for damaged DNA repair in archaeal order Thermococcales

  • A novel DNA repair pathway found in achaeal order Thermococcales International conference

    Shiraishi, M, Ishono, S, Egashira, Y, Kiyonari, S, Yamagami, T, Cann, I, Ishino, Y

    Molecular Biology of Archaea 5  2016.8 

     More details

    Language:English  

    Country:Other  

    A novel DNA repair pathway found in achaeal order Thermococcales

  • A Novel DNA Repair Pathway for Damaged Bases in Thermococcales International conference

    Shiraishi, M, Ishono, S, Egashira, Y, Kiyonari, S, Yamagami, T, Cann, I, Ishino, Y

    Extremophiles2016 (11th International Congress)  2016.9 

     More details

    Language:English  

    Country:Other  

    A Novel DNA Repair Pathway for Damaged Bases in Thermococcales

  • Endonuclease Q Acts on Various Mutagenic Bases in Hyperthermophilic Archaea International conference

    Shiraishi, M, Ishino, S. Yamagami, T, Egashira, Y, Kiyonari, S, Iwai, S, Ishino, Y

    Thermophiles2019 (15th International Congress)  2019.9 

     More details

    Language:English  

    Country:Other  

    Endonuclease Q Acts on Various Mutagenic Bases in Hyperthermophilic Archaea

  • アーキアから見出された新規修復タンパク質、エンドヌクレアーゼQの基質認識機構

    白石 都, 岩井成憲

    第42回日本分子生物学会年会  2019.12 

     More details

    Language:English  

    Country:Other  

  • Thermococcus kodakarensis由来エンドヌクレアーゼIIIとその変異体を用いた機能解析

    水谷謙斗, 山元淳平, 岩井成憲, 白石都

    第42回日本分子生物学会年会  2019.12 

     More details

    Language:Others  

    Country:Other  

  • Characterization of archaeal Endonuclease V

    The 48th International Symposium on Nucleic Acids Chemistry  2021.11 

     More details

    Language:Others  

    Country:Other  

    Characterization of archaeal Endonuclease V

  • アーキア型RPA及びRadAのRNAに対する機能解析

    日比寛菜, 白石都, 岩井成憲

    極限環境生物学会2021年度(第22回)年会  2021.11 

     More details

    Language:Others  

    Country:Other  

  • Cdt1およびCdt1結合性クロマチン制御因子によるクロマチン構造変換機構の解明

    坂井花菜, 辻田沙伎, 東寅彦, 勝木陽子, 杉本のぞみ, 白石都, 藤田雅俊

    第45回日本分子生物学会年会  2022.11 

     More details

    Language:Others  

    Country:Other  

  • アーキア研究から見出された新しいDNA修復因子と機能

    白石 都

    第45回日本分子生物学会年会  2022.12 

     More details

    Language:Others  

    Country:Other  

  • クリックケミストリーを用いたCRISPR-Cas模倣型タンパク質の開発とイメージングへの応用

    中村惇, 白石都, 山本純平, 鈴木啓一郎

    第46回日本分子生物学会年会  2023.12 

     More details

    Language:Others  

    Country:Other  

▼display all

Industrial property rights

Patent   Number of applications: 1   Number of registrations: 2
Utility model   Number of applications: 0   Number of registrations: 0
Design   Number of applications: 0   Number of registrations: 0
Trademark   Number of applications: 0   Number of registrations: 0

Academic Activities

  • Screening of academic papers

    Role(s): Peer review

    2021

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

Research Projects

  • ヒトCdt1がライセンス化において果たすクロマチン構造制御のメカニズムの解明

    2024

      More details

    Grant type:Donation

  • 古細菌由来の核酸関連酵素を用いた等温核酸増幅促進法の開発

    2023

      More details

    Grant type:Donation

  • -

    2023

      More details

    Authorship:Principal investigator  Grant type:On-campus funds, funds, etc.

  • Cdt1の新たな活性によって誘導されるヌクレオソームの構造解析

    2023

    令和5年度 出産・育児復帰者支援

      More details

    Authorship:Principal investigator  Grant type:On-campus funds, funds, etc.

  • 古細菌が持つ独特なヌクレオチド除去修復機構の解明

    Grant number:22K14832  2022 - 2025

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Grant type:Scientific research funding

  • 典型的なDNA修復因子が示す新規RNA結合活性の意義

    2022

      More details

    Grant type:Donation

  • 古細菌が持つXPBとXPDの役割の解明

    2020

      More details

    Grant type:Donation

  • 生物界に幅広く存在するEndonuclease Vの普遍的役割の解明

    2019

      More details

    Grant type:Donation

  • 等温反応かつ正確なDNA増幅法の開発

    2018

      More details

    Grant type:Donation

  • 超好熱性アーキアPyrococcus furiosus由来Endonuclease Qが介するDNA修復経路の解明

    2017

      More details

    Grant type:Donation

  • 超好熱性アーキアに存在する極限環境下の特異的DNA修復機構の解明

    2014 - 2016

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

▼display all

Class subject

  • 染色体生物学とそのがん研究への応用

    2024.4 - 2024.9   First semester

  • 創薬科学総論

    2023.10 - 2024.3   Second semester

  • 生物薬学研究

    2023.4 - 2024.3   Full year

  • 染色体生物学とそのがん研究への応用

    2023.4 - 2023.9   First semester

  • 創薬科学総論

    2022.10 - 2023.3   Second semester

Travel Abroad

  • 2021.11 - 2022.2

    Staying countory name 1:United States   Staying institution name 1:University of Illinois at Urbana-Champaign

  • 2014.5 - 2016.12

    Staying countory name 1:United States   Staying institution name 1:University of Illinois at Urbana-Champaign