Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1246/bcsj.20210316

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/acs.joc.1c00837

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： https://doi.org/10.1021/acs.joc.1c00161

Language：English   Publishing type：Research paper (scientific journal)  

DOI： https://doi.org/10.1142/S1088424621500292

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/d0cc04274a

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1246/cl.200241

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jorganchem.2019.121058

Language：English   Publishing type：Research paper (scientific journal)  

DOI： https:// doi.org/ 10.1016/ j.coelec.2017.12.001

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c7dt03742b

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c7cc04377e

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/cplu.201600303

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c6dt00556j

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/anie.201507782

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.5857/RCP.2015.4.1.9

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c4dt01360c

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/cplu.201402081

Language：English   Publishing type：Research paper (international conference proceedings)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

The B12-TiO2 hybrid catalyst was effectively immobilized on a glass plate, and the immobilized catalyst shows an efficient reactivity for various molecular transformations, such as the 1,2-migration of the phenyl group and dechlorination of perchloroethylene during irradiation by UV light.

Language：English   Publishing type：Research paper (scientific journal)  

A new macrocyclic ligand (L1) having four crown ether moieties at the peripheral position was synthesized by a conventional Schiff-base condensation reaction. The corresponding dinickel (1) and dicobalt (2) complexes formed a unique face-to-face dimerized structure by complexation with a Cs+ ion, which was characterized by 1H NMR, UV-vis, and electro-spray ionization (ESI)-MS. Multi-sandwich structures consist of a 2:1 interaction of the benzo-18-crown-6-ether with the Cs+ ion afforded a significantly high overall formation constant (Kall= 25.9±0.9 at 298 K). The redox behavior of the assembled structure of the dicobalt complex was investigated by cyclic voltammetry. In the dimerized structure, two sequential reductions ascribed to the CoIICoII/CoIICoI and CoIICoI/CoICoI couples were observed at -1.13 V (E1) and -1.36 V (E2) vs. Ag/AgCl, and both potentials were separated by E = E1- E2 = 0.23 V. A mixed valence state (CoIICoI) was stabilized in the complex with the comproportionation constant Kcom = 7.7x103 at 298 K.

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

The B12-TiO2 hybrid catalyst was effectively used for the radical reactions, such as 1,2-migrations of the phenyl group and the acyl group under irradiation by UV light, and the selectivity of the reaction was controlled by the solvent system.

Language：English   Publishing type：Research paper (scientific journal)  

A cobalamin derivative, cobyrinic acid, was effectively immobilized on TiO2, and the hybrid TiO2 was characterized by UV-VIS, XPS, MALDI TOF-MS as well as TEM analysis. The hybrid TiO2 exhibits high reactivity for dehalogenation of various organic halides such as phenethyl bromide, benzyl bromide and 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethane (DDT) under irradiation with UV light at room temperature.

Language：English   Publishing type：Research paper (scientific journal)  

A new dinuclear complex of cobalt (III) having double bis-crowns moieties (1) was synthesized in a one-pot multi-step reaction between dinucleating ligand (H2L1), Co(OAc)•4H2O, and 4’-aminomethylbenzo-15-crown 5-ether under aerobic condition. The complex was characterized by UV-vis, IR, NMR, and CSI-mass spectroscopies, and axial coordination of 4’-aminomethylbenzo-15-crown 5-ether on both cobalt centers was confirmed. The bis-crowns moieties of 1 acted as potassium ion binding site with a large association constant (K) of 1.97x105 M-1 (1:1) caused by pre-organized bis-crowns structure. Solvent extraction of K+ (potassium picrate) with 1 was investigated by UV-vis and NMR, and extracted K+ was quantified by atomic absorption/flame emission spectrophotometer. 　The cyclic voltammogram (CV) of 1 showed irreversible redox waves at -0.57 V and +0.16 V vs. Ag/AgCl in DMF which are ascribed to Co(III) and Co(II) redox couple. The large peak separation (Δ0.73 V) of this redox couple indicates the association and dissociation of the axial amine on cobalt centers. The irreversible reduction peak of 1 at -0.57 V was shifted to positive direction by 80 mV in the presence of potassium ion, showing the complexation of 1 with potassium ion. Reversible formation and decomposition of the double bis-crown moieties in 1 caused by the electrical stimulus were also investigated by thin-layer UV-VIS spectroelectrochemistry. The switching of double bis-crowns structure of 1 was established over four times with response to electrical energy.

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

POrphycene was covalently immobilized in a sol-gel silica film deposited on a glass plaete.

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/ic051482o

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0040-4039(02)02022-1

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0040-4039(03)01252-8

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/b212863b

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1246/bcsj.75.1553

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0040-4039(02)00923-1

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0022-0728(01)00418-1

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/b010022f

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1246/cl.2001.346

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0040-4039(01)00040-5

Language：English   Publishing type：Research paper (scientific journal)  

Language：Japanese   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

This concept focuses on dual-catalysis using metal complexes and heterogeneous photocatalysts. Vitamin B12 derivatives are sophisticated metal complexes that facilitate enzymatic reactions in the biological systems. The B12 enzymes inspired reactions catalytically proceed in dual-catalyst systems of B12 derivatives and heterogeneous photocatalysts, such as titanium oxide (TiO2) and metal-organic frameworks (MOFs), under light irradiation. The cobalt ions in B12 derivatives are effectively reduced by photoexcited photocatalysts, producing low-valent Co(I) species. The photoinduced nucleophilic Co(I) species react with an alkyl halide to form an organometallic complex with a Co−C bond. The Co−C bond dissociates during photolysis to generate alkyl radicals. Based on this mechanism, dual-catalysis effectively promotes various light-driven organic syntheses and light-driven dehalogenation reactions of toxic alkyl halides. The trends of the dual-catalyst system and recent progress in this field are discussed in this concept.

DOI： 10.1002/cplu.202400041

Web of Science

Scopus

PubMed

researchmap

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Hosokawa Powder Technology Foundation  

<p>A hybrid catalyst composed of naturally occurring metal complexes and semiconductor photocatalysts enables a variety of molecular transformations in a green and sustainable manner. In this study, we have developed the visible light-driven hybrid catalyst (B₁₂–M<i>ⁿ</i>⁺/TiO₂) composed of “vitamin B₁₂” and “metal ion-grafted TiO₂ (M<i>ⁿ</i>⁺/TiO₂)”. The B₁₂–M<i>ⁿ</i>⁺/TiO₂ was prepared by mixing of B₁₂ derivatives and M<i>ⁿ</i>⁺/TiO₂, and this hybrid catalyst was thoroughly characterized by various measurements. The B₁₂–M<i>ⁿ</i>⁺/TiO₂ effectively produced reactive Co(I) species under visible light irradiation. In addition, the reactivity of Co(I) species toward CO₂ reduction was investigated in this study.</p>

DOI： 10.14356/hptf.22507

CiNii Research

researchmap

Language：Japanese   Publisher：The Society of Synthetic Organic Chemistry, Japan  

<p>The bioinspired catalyst system was developed in the interdisciplinary fields of bioinorganic chemistry and catalytic chemistry. In nature, enzymes catalyze various molecular transformations under mild conditions with a high efficiency and selectivity. Therefore, we can learn about many excellent systems from nature. As for the catalyst design, a metal complex inspired by the active site of a metal enzyme has been developed and the combination of the metal complex with a redox system should form an excellent catalytic system. Based on this concept, we can use various redox systems such as electrochemistry and photo-excited chemistry to construct a catalyst system. Among the metal complexes inspired from natural metal enzymes, the cobalt ion containing the B₁₂ derivative is the focus on this account. Organometallic B₁₂ complexes are unique metal complexes having a cobalt-carbon σ-bond that exist in biological systems. Cleavage of the metal-organic σ-bond initiates many B₁₂ dependent enzymatic reactions. Based on the unique properties of alkylated cobalt complex, many B₁₂-inspired reactions have been developed. Here the visible light driven B₁₂ inspired reaction for the synthesis of various compounds from organic halides as carbon source were summarized, and the combination of the B₁₂ derivative as redox catalyst in electroorganic synthesis for the conversion of various trichloromethylated organic compounds to amides was reviewed.</p>

DOI： 10.5059/yukigoseikyokaishi.82.152

Web of Science

Scopus

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)   Publisher：Organic Chemistry Frontiers  

Functional group migrations are one of the most powerful strategies in the construction of complex molecules. [1,3]-Migrations, especially 1,3-C → C migrations are more challenging for the difficulty in the formation of highly strained four-membered ring intermediates. In the limited reports, narrow substrate tolerance, basic additives or high temperature are unavoidable. Herein, visible-light-mediated novel 1,3-C → C migrations of N-allyl enamines under base-free conditions are researched. Radical-triggered 1,3-C → C acyl and cyano migrations were achieved, initiated by a reductive radical-polar crossover (RPC) process. A variety of biologically active cyclic imines were synthesized in good-to-excellent yields under very mild reaction conditions. DFT calculations support our proposal that the radical cyclization of N-allyl enamines facilitates the reductive RPC process, which triggers the formation of strained four-membered ring intermediates for 1,3-migrations. Thus, a tandem radical cyclization/RPC/1,3-C → C migration process has been developed under base-free conditions. Furthermore, from the same N-allyl enamines, different cyclic imines, i.e., (3-azabicyclo[3.1.0]hex-2-enes), could be achieved in high selectivity mediated by the acridine photosensitizer and Co(ii) additive.

DOI： 10.1039/d3qo01849k

Web of Science

Scopus

Publishing type：Research paper (scientific journal)   Publisher：World Scientific Pub Co Pte Ltd  

Reductive dehalogenation of an aryl halide (Ar-X) subsequent coupling with bis(pinacolato)diboron (B₂pin[Formula: see text] to form an arylboronate (Ar-Bpin) by the photo-excited B[Formula: see text] complex of the Co[Formula: see text] oxidation state with an iridium photosensitizer (PS), [Ir(dtbbpy)(ppy)₂]PF₆, under anaerobic conditions was reported. The robust B[Formula: see text] complex and iridium PS provided the highest turnover numbers of over 3,800 for the borylation reaction at room temperature. The Co^I state of the B[Formula: see text] complex was formed via the reductive quenching pathway of [Ir(dtbbpy)(ppy)₂]PF₆ by visible light irradiation in the presence of [Formula: see text], [Formula: see text]-diisopropylethylamine ([Formula: see text]-Pr₂NEt) as a sacrificial electron donor (SED), which was confirmed by a photoluminescence lifetime analysis. A picosecond time-resolved spectroscopic analysis showed that the electron transfer from the excited Co[Formula: see text] state of the B[Formula: see text] complex ([Formula: see text]Co[Formula: see text] to the Ar-X occurred in the order of the rate constants for electron transfer ([Formula: see text], Ar-I [Formula: see text] Ar-Br [Formula: see text] Ar-Cl. Based on the mechanistic studies, dual excitation of PS and the B[Formula: see text] complex is involved in the catalytic reaction and single electron transfer (SET) from [Formula: see text]Co[Formula: see text] to Ar-X could provide the aryl radical by fragmentation of the Ar-X radical anion. The aryl radical should react with the radical trapping reagent, B₂pin₂, to form the Ar-Bpin product.

DOI： 10.1142/S1088424623500815

Web of Science

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

DOI： 10.1021/acs.inorgchem.3c00882

Web of Science

Scopus

PubMed

researchmap

Publishing type：Research paper (scientific journal)  

Visible light-driven benzoyl azides formation catalyzed by a rhodium ion modified TiO2 (Rh3+/TiO2) is reported. The Rh3+/TiO2 was prepared as a visible light responsive photocatalyst by a simple procedure from TiO2 and RhCl3・3H2O. The Rh3+/TiO2 exhibited a broaden visible light absorption from 400 nm to 600 nm. Benzoyl azide formation from a benzotrichloride and a trimethylsilyl azide (TMS-N3) was performed catalyzed by the Rh3+/TiO2 under visible light irradiation (λ ≥ 420 nm) in air at room temperature. In this reaction, the benzotrichloride was effectively reduced by the single electron transfer (SET) from the Rh3+/TiO2, and the benzoyl azide was produced in 71% yield via the reaction between the benzoyl chloride and TMS-N3. In addition, several benzotrichloride derivatives were applied to this reaction and the corresponding benzoyl azide derivatives were formed in up to 71% yield. A kinetic analysis was also performed on these reactions, and it was suggested that the SET is the rate determining step in this reaction.

DOI： 10.1016/j.jpap.2023.100170

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

Continuous flow reactors with immobilized catalysts are in great demand in various industries, to achieve easy separation, regeneration, and recycling of catalysts from products. Oxidation of alcohols with 4-amino-TEMPO-immobilized monolith catalyst was investigated in batch and continuous flow systems. The polymer monoliths were prepared by polymerization-induced phase separation using styrene derivatives, and 4-amino-TEMPO was immobilized on the polymer monolith with a flow reaction. The prepared 4-amino-TEMPO-immobilized monoliths showed high permeability, due to their high porosity. In batch oxidation, the reaction rate of 4-amino-TEMPO-immobilized monolith varied with stirring. In flow oxidation, the eluent permeated without clogging, and efficient flow oxidation was possible with residence times of 2–8 min. In the recycling test of the flow oxidation reaction, the catalyst could be used at least six times without catalyst deactivation.

DOI： 10.3390/polym14235123

Web of Science

Scopus

PubMed

CiNii Research

researchmap

Language：English   Publisher：ELSEVIER SCIENCE SA  

Pyrrole-containing metal complexes widely exist in nature, for example, vitamin B-12, heme, chlorophyll, and their derivatives. Each of them shows significant functions, which are essential for life. To mimic their important functions and substance conversion reactions, numerous pyrrole-containing metal complexes have been synthesized and investigated. This review mainly focuses on cobalt complexes having pyrrolecontaining ligands and the recent progress of molecular transformations catalyzed by the complexes, especially the vitamin B-12-related cobalt complexes and porphycene cobalt complexes. A variety of reaction systems, which enable a number of molecular transformations under mild conditions is described. The construction of new reaction systems and a combination of the materials inspired by natural systems is a promising and effective approach to realizing eco-friendly and cost-effective reaction systems. (C) 2022 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.ccr.2022.214690

Web of Science

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：CHEMICAL SOC JAPAN  

Heterogeneous catalysts composed of a vitamin B-12 derivative with a polymer or mesoporous silica were synthesized and characterized. These two types of catalysts were used in alkane oxidation reactions with mCPBA oxidant, and improved catalytic efficiency was obtained using the polymer supported B-12 catalyst with a monolith structure compared to that of the monomeric B-12 catalyst. The catalytic effects were also evaluated in several alkane substrates and the polymer supported B-12 catalyst showed a better performance in all reactions compared to the silicasupported B-12 catalyst.

DOI： 10.1246/bcsj.20220161

Web of Science

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：CHEMICAL SOC JAPAN  

The development of highly-functional visible light-driven hybrid catalysts (B-12-Mn+/TiO2) prepared from B-12 complexes (B-12) derived from natural vitamin B-12, earth-abundant metal ions (Mn+), and titanium oxide (TiO2) was reported. The metal ions, such as Cu2+, Ni2+, Fe2+, Zn2+, Mn2+, Al3+, and Mg2+, were modified on the surface of TiO2 (2.4 x 10(-5)-9.9 x 10(-5) mol/g) to obtain effective response to visible light, and the B-12 complex was also loaded (6.2 x 10(-6)-1.1 x 10(-5) mol/g) to produce a highly-functional hybrid catalyst. Amide formations from dichlorodiphenyltrichloroethane (DDT) catalyzed by the B-12-Mn+/TiO2 proceeded in up to 89% yields in the presence of triethylamine (NEt3) under visible light irradiation (lambda >= 420 nm) in air at room temperature. These hybrid catalysts could be classified into two groups based on these reactivities, and it was found that the B-12-Mg2+/TiO2 showed the most effective catalytic activities of all the prepared samples. The B-12-Mg2+/TiO2 also catalyzed the syntheses of fine chemicals, such as N,N-diethyl-3-methylbenzeamide (DEET), and N,N-diethylcyanoformamide, from the corresponding trichloromethyl compounds (FG-CCl3) with about 80% yields.

DOI： 10.1246/bcsj.20220080

Web of Science

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：AMER CHEMICAL SOC  

The oxidation of alkanes with m-chloroperbenzoic acid (mCPBA) catalyzed by the B12 derivative, heptamethyl cobyrinate, was investigated under several conditions. During the oxidation of cyclohexane, heptamethyl cobyrinate works as a catalyst to form cyclohexanol and cyclohexanone at a 0.67 alcohol to ketone ratio under aerobic conditions in 1 h. The reaction rate shows a firstorder dependence on the [catalyst] and [mCPBA] while being independent of [cyclohexane]; Vobs = k2[catalyst][mCPBA]. The kinetic deuterium isotope effect was determined to be 1.86, suggesting that substrate hydrogen atom abstraction is not dominantly involved in the rate-determining step. By the reaction of mCPBA and heptamethyl cobyrinate at low temperature, the corresponding cobalt(III)acylperoxido complex was formed which was identified by UV-vis, IR, ESR, and ESI-MS studies. A theoretical study suggested the homolysis of the O-O bond in the acylperoxido complex to form Co(III)-oxyl (Co-O center dot) and the m-chlorobenzoyloxyl radical. Radical trapping experiments using Ntert-butyl-alpha-phenylnitrone and CCl3Br, product analysis of various alkane oxidations, and computer analysis of the free energy for radical abstraction from cyclohexane by Co(III)-oxyl suggested that both Co(III)-oxyl and the m-chlorobenzoyloxyl radical could act as hydrogen-atom transfer reactants for the cyclohexane oxidation.

DOI： 10.1021/acs.inorgchem.2c01174

Web of Science

Scopus

PubMed

researchmap

DOI： 10.1142/S108842462150053X

Web of Science

Publisher：Journal of Porphyrins and Phthalocyanines  

One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.

DOI： 10.1142/S1088424621500292

Web of Science

Scopus

Language：English   Publishing type：Research paper (scientific journal)   Publisher：WORLD SCIENTIFIC PUBL CO PTE LTD  

A new meso-tetrakis(3,5-di-tert-butylphenyl) substituted porphycene and its cobalt complex were synthesized and characterized. Several meso-tetraarylporphycene cobalt complexes having different substituents showed catalytic activity for the hydrogen gas evolution reaction (HER) in the presence of trifluoroacetic acid (TFA) under electrochemical reductive conditions. The electrochemical potential of the HER was -1.50V vs. Ag/AgCl in THF. The active species of this reaction were determined to be the ligand reduced species of Co(II) porphycenes. The catalytic efficiencies of the cobalt complexes of meso-aryl substituted porphycenes and meso-tetraphenylporphyrin were compared and meso-tetraphenyl porphycene cobalt complex exhibited the best current efficiency of 72%. Based on these experimental results and theoretical calculations, we proposed a possible HER mechanism of this system.

DOI： 10.1142/S108842462250016X

Web of Science

Scopus

researchmap

Language：English   Publishing type：Research paper (scientific journal)   Publisher：WORLD SCIENTIFIC PUBL CO PTE LTD  

The electrochemical properties of beta-octaethylporphycene iridium complex (Ir-OEPo) were determined. Based on the electro-spectro measurement results, the reduction of Ir-OEPo did not occur at the central metal but at the ligand, while the reduction of beta-octaethylporphyrin iridium complex (Ir-OEPor) occurred at the central iridium. A catalytic current was observed during the cyclic voltammetry (CV) measurements with trifluoroacetic acid (TEA) under a reductive condition, indicating the catalytic reactivity of Ir-OEPo for the hydrogen evolution reaction (HER). By constant potential electrolysis, hydrogen gas was detected by gas chromatography (GC) and the catalytic reactivity of Ir-OEPo was confirmed. The HER mechanism via ligand reduction of macrocycfic aromatic complexes could be one of the concepts for the development of new catalysts.

DOI： 10.1142/S1088424622500092

Web of Science

Scopus

researchmap

Language：English   Publisher：Vitamins and Hormones  

Bioorganometallic structure found in coenzyme B12 is a key component in B12-dependent enzymatic reactions in natural enzymes. Cleavage of a cobalt-carbon bond in organometallic B12 compound provide reactive intermediate for molecular transformations. Application of the bioorganometallic B12 in organic synthesis have been developed using natural vitamin B12 as well as synthetic vitamin B12 derivatives as a bioinspired catalyst in organic solvent. Vitamin B12 derivatives composed of corrinoid structure should form stable organometallic compound having a cobalt-carbon bond. Using the unique property of the organometallic vitamin B12 derivatives, various catalytic reactions have been developed in synthetic organic chemistry. The dual catalytic system of vitamin B12 derivatives and photocatalyst, such as Ru(II) polypyridyl complex or titanium oxide, could construct light-driven molecular transformations. The B12-dependent enzymes mimic reactions, such as the dechlorination of organic halides and the radical mediated isomerization reactions, catalytically proceed in the dual catalyst system. Electroorganic syntheses mediated by the vitamin B12 derivatives have been developed as green molecular transformations. The redox active vitamin B12 derivatives shows a unique catalysis in the electroorganic synthesis, such as alkene and alkyne reductions.

DOI： 10.1016/bs.vh.2022.01.015

Web of Science

Scopus

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1142/S1088424619500780

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.gee.2019.03.001

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c9cc06185a

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/cplu.201800586

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/adsc.201801707

Language：English   Publishing type：Research paper (scientific journal)  

The dihydrogenated porphycene cobalt(ii) complex was synthesized and electrochemical experiments were carried out. The one-electron reduction of the complex proceeded at the central metal to afford the Co(i) species; in contrast, for the non-hydrogenated porphycene cobalt(ii) complex, the one-electron reduction gave the ligand reduced radical anion species. The reactivity of the one-electron reduced species with alkyl halides showed clear differences between the complexes. Hydrogenation of the β-position of the porphycene makes it possible to generate a central cobalt reduced species possessing a higher reactivity than the ligand reduced radical anion species.

DOI： 10.1039/c8dt03743d

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c7ra13037f

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/cplu.201800522

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1246/cl.180355

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.5059/yukigoseikyokaishi.76.894

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/acsomega.8b00239

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jinorgbio.2017.07.021

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c7ra02062g

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jorganchem.2017.02.002

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/c6dt00355a

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jorganchem.2014.11.015

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.tetlet.2014.03.028

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.tetlet.2013.08.026

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Publishing type：Research paper (scientific journal)  

Redox behavior and Catalysis of B12 immobilized hyper-branched polymer were reported.

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/S0040-4039(03)01587-9

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1107/S0108270102013483

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/ic0155434

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/om010141p

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/b100974p

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1021/ic9600994

Language：English   Publishing type：Research paper (scientific journal)  

Responsible for pages：Chapter 3   Language：English   Book type：Scholarly book

Responsible for pages：Chapter 19   Language：English   Book type：Scholarly book

Language：Japanese   Book type：General book, introductory book for general audience

Language：Japanese   Book type：General book, introductory book for general audience

Language：Japanese   Book type：Scholarly book

Language：Japanese   Book type：Scholarly book

Language：Japanese   Book type：Scholarly book

Responsible for pages：Vol. 10, pp313-370   Language：English   Book type：Scholarly book

Bioinspired catalysts with B12 enzyme functions were reviewed.

Total pages：500  

CiNii Research

Event date： 2022.12

Language：English   Presentation type：Oral presentation (general)  

Country：Singapore  

Event date： 2022.12

Language：English  

Venue：Singapore   Country：Singapore  

researchmap

Event date： 2022.11

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.11

Language：English  

Venue：On-line   Country：Japan  

researchmap

Event date： 2022.10

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：オンライン   Country：Japan  

Event date： 2022.10

Language：Japanese  

Venue：オンライン   Country：Japan  

researchmap

Event date： 2022.7

Language：English   Presentation type：Oral presentation (general)  

Country：Spain  

Event date： 2022.7

Language：English  

Venue：Madrid   Country：Spain  

researchmap

Event date： 2022.7

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：北九州   Country：Japan  

Event date： 2022.7

Language：Japanese  

Venue：北九州   Country：Japan  

researchmap

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：オンライン   Country：Japan  

生体内での酵素反応は、温和な常温•常圧下で進行し、また有機合成化学的にも魅力的な反応が多い．我々は、天然の有機金属錯体であるビタミンB12依存性酵素に着目し、そのモデル錯体を用いた天然酵素を範とする様々な物質変換反応を開発してきた（官能基転位反応、脱塩素化反応、クロスカップリング反応等）1,2．これらの反応は、超求核性を示すCo(I)種と有機ハロゲン化物との反応により生成するコバルト-炭素結合を有するアルキル錯体が中間体として進行している．近年、可視光駆動型錯体触媒の開発は、太陽光利用を目指した次世代のクリーン触媒の発展における重要な課題である．このような観点から最近当研究室では、ビタミンB12誘導体とロジウムイオンを表面修飾した酸化チタン複合触媒を合成し、可視光応答型の物質変換反応を報告している3．本研究では、より汎用性の高い触媒開発を目指し、安価な遷移金属イオンやアルカリ土類金属イオンを修飾した酸化チタン複合触媒を開発し、その可視光応答性を利用した新規不飽和ニトリル合成反応の開発を行った．

Event date： 2020.12

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2020.11

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：オンライン   Country：Japan  

酸素敏感性の低原子価Co(I)種の利用及びアルキル錯体の開裂から生成するラジカル種を経由する触媒反応においては、嫌気性条件下で行うことが常識であった。しかし電解還元などにより常に電極から電子を供給し続けることが可能な系では、好気性条件下においても活性Co(I)種が生成しトリクロロアセトニトリルの電解反応を酸素共存下で行うことで、酸塩化物を中間体としたアミド合成反応の開発に成功した。

Event date： 2020.4

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2019.7 - 2019.8

Language：English   Presentation type：Oral presentation (general)  

Country：United Kingdom  

Event date： 2019.5

Language：English   Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2019.2

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：福岡   Country：Japan  

Event date： 2018.12

Language：English   Presentation type：Oral presentation (general)  

Country：Singapore  

Event date： 2018.11

Language：English   Presentation type：Oral presentation (general)  

Country：Taiwan, Province of China  

Event date： 2018.10 - 2018.11

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2018.10

Language：English   Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2018.9

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：函館   Country：Japan  

金属酵素の活性中心に着目し,その構造を再現した生体関連金属錯体を合成し,様々な物質変換反応へと応用した．その際,錯体触媒を還元活性化する手法として,電解反応や光触媒反応を用いることで,高効率でクリーンな反応システムを構築することができた．これらの反応は錯体触媒や電極および光触媒単独では進行しないものであり,両機能を相乗させることで初めて達成することができた．

Event date： 2018.1

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.10

Language：English   Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2017.9

Language：English   Presentation type：Oral presentation (general)  

Country：Germany  

Event date： 2017.8 - 2017.9

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：千葉   Country：Japan  

様々な金属錯体を、電極、酸化物半導体、光増感剤、および高分子化イオン液体などと組み合わせた複合触媒を開発し、様々な物質変換反応の開発を行ってきた。本講演では、これらの複合触媒の開発から最近の応用展開まで、著者らの研究を中心に紹介した。

Event date： 2017.6

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：北海道   Country：Japan  

様々な金属錯体を、電極、酸化物半導体、光増感剤、および高分子化イオン液体などと組み合わせた複合触媒を開発し、様々な物質変換反応の開発を行ってきた。本講演では、これらの複合触媒の開発から最近の応用展開まで、著者らの研究を中心に紹介した。

Event date： 2017.1

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：静岡大学   Country：Japan  

光線力学治療のために、ポルフィリノイド系光化学増感剤の設計と合成、およびその光物性について報告した。

Event date： 2016.9

Language：English   Presentation type：Oral presentation (general)  

Country：Russian Federation  

Event date： 2016.4

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.4

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese  

Venue：大阪大学   Country：Japan  

Event date： 2016.2 - 2016.12

Language：English   Presentation type：Oral presentation (general)  

Country：New Zealand  

Event date： 2016.2

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.12

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Event date： 2015.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：宇都宮大学   Country：Japan  

Event date： 2015.10

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：同志社大学   Country：Japan  

Event date： 2015.8

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：奈良先端科学技術大学院大学   Country：Japan  

Event date： 2015.6

Language：Japanese  

Venue：長崎大学   Country：Japan  

Event date： 2015.6

Language：Japanese  

Venue：京都大学   Country：Japan  

Event date： 2014.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：京都大学   Country：Japan  

我々は、ビタミンB12のモデル化合物と無機材料である酸化チタン（TiO2）を複合したハイブリッド触媒を作製し、光駆動型の物質変換反応の開発を行って来た。ビタミンB12は中心にコバルトイオンを含む金属錯体であり、Co(I)種へと還元することで高い求核性を示し、各種求電子剤との反応に利用出来る（プロトン還元、有機塩素化合物の脱塩素化反応等）。本複合触媒においては酸化チタンの励起電子の還元力を利用することで、還元Co(I)種を生成しているが、TiO2の励起にはバンドギャップエネルギーに相当する紫外線照射が必要であった。本討論会では、カテコールとビタミンB12誘導体をそれぞれ別個に修飾したTiO2を作成し、両者を混合して用いることで、電荷分離状態の安定化5)によるさらなる反応の効率化を目指した（図1b）。また用いるTiO2の結晶系の違いに起因する伝導体電位(CB)の違いが、本システムにどのような影響を及ぼすかについても検討した。

Event date： 2014.11

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：熊本   Country：Japan  

有機塩素化合物を基質とし、コバルト錯体を電解メデイエーターとする還元的脱塩素化反応を好気性条件下で行ったところ、アルコール溶媒中では対応するエステル化合物が生成し、またアミン存在下ではアミド化合物が生成することを見出した。またESRスピントラップ実験より、基質ラジカルと溶存酸素との反応により生成するオキシラジカル種が中間体として生成することを確認した。

Event date： 2014.10

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：横浜   Country：Japan  

我々は、生体関連金属錯体であるビタミンB12とルテニウム光増感剤を組み合わせた、光駆動型のビタミンB12触媒システムを開発してきた。なかでも、高分子の側鎖に両錯体を導入したハイブリッドポリマーにおいては、ポリマー内での高効率な光誘起電子移動反応が進行することを見出している。またイオン液体を反応溶媒とすることで、ビタミンB12錯体の反応性が向上し、また触媒であるビタミンB12錯体のリサイクル化にも成功している。一方で、高粘性なイオン液体中では分子間反応が抑制され、反応の加速化にはさらなる工夫が必要であることも判明した。この点を踏まえて、イオン液体中での高効率な触媒反応を達成するために、イオン液体構造を高分子鎖に導入し、さらに側鎖にビタミンB12とRu光増感剤を導入したハイブリッド型高分子化イオン液体の開発も行っている。今回我々は、新たなアプローチとして、電子メディエータ-能を有するイオン液体を溶媒とする光触媒系の構築を行った。イオン液体を溶媒兼電子メディエータ-とすることで、希薄なRu光増感剤濃度条件下でも高効率な光駆動型のビタミンB12触媒反応が進行することが期待される。

Event date： 2014.10

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：北海道大学   Country：Japan  

我々は、生体関連金属錯体であるビタミンB12とRu光増感剤を組み合わせた、光駆動型のビタミンB12人工酵素システムを開発してきた。なかでも、高分子の側鎖に両錯体を導入したハイブリッドポリマーにおいては、ポリマー内での高効率な光誘起電子移動反応が進行することを見出している。またイオン液体を反応溶媒とすることで、ビタミンB12錯体の反応性が向上し、また触媒であるビタミンB12錯体のリサイクル化にも成功している。しかし一方で、高粘性なイオン液体中では分子間反応が抑制され、反応の加速化にはさらなる工夫が必要であることも判明した。そこで本研究ではこれらの結果を踏まえ、イオン液体中での高効率な触媒反応を達成するために、1）イオン液体構造を高分子に導入し、さらに側鎖にビタミンB12とRu光増感剤を導入したハイブリッド型高分子化イオン液体の合成、2）電子メディエータ-能を有するイオン液体を溶媒とする光触媒反応を行った。高分子化イオン液体はイオン伝導材料やCO2吸着材料として魅力的であるが、触媒としての応用例は少ない4)。またイオン液体を溶媒兼電子メディエータ-として使用した例はなく、新規なアプローチである。

Event date： 2014.9

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：長崎大学   Country：Japan  

我々は、生体関連金属錯体であるビタミンB12とRu光増感剤を組み合わせた、光駆動型のビタミンB12人工酵素システムを開発してきた。なかでも、高分子の側鎖に両錯体を導入したハイブリッドポリマーにおいては、ポリマー内での高効率な光誘起電子移動反応が進行することを見出している。またイオン液体を反応溶媒とすることで、ビタミンB12錯体の反応性が向上し、また触媒であるビタミンB12錯体のリサイクル化にも成功している。しかし一方で、高粘性なイオン液体中では分子間反応が抑制され、反応の加速化にはさらなる工夫が必要であることも判明した。そこで本研究ではこれらの結果を踏まえ、イオン液体中での高効率な触媒反応を達成するために、1）イオン液体構造を高分子に導入し、さらに側鎖にビタミンB12とRu光増感剤を導入したハイブリッド型高分子化イオン液体の合成、2）電子メディエータ-能を有するイオン液体を溶媒とする光触媒反応を行った。

Event date： 2014.9

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.8

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：筑波国際会議場   Country：Japan  

我々は、天然金属酵素の活性中心に存在するビタミンB12のモデル化合物と無機材料である酸化チタン等の光触媒を複合したハイブリッド触媒を作製し、光に応答して機能発現する環境調和型の機能材料の開発を行って来た1)。過去の討論会では、酸化チタン粒子に表面ゾルーゲル法を用いて共有結合によりビタミンB12誘導体を固定化したハイブリッド触媒の作製とその水素発生触媒としての機能について報告した2)。本発表では、本触媒のさらなる機能として、炭素—炭素二重結合還元能について検討した。

Event date： 2014.7

Language：English   Presentation type：Oral presentation (general)  

Country：Austria  

Event date： 2014.6

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：長良川国際会議場   Country：Japan  

水素は次世代のクリーンエネルギーとして注目され、様々な水素生成技術が開発されている。しかし現状の水素発生触媒は、化石燃料を原料として製造されており、また使用する触媒は高価で複雑なものであり、安価な遷移金属を用いた触媒の開発が強く望まれている。そこで本研究では、コバルト錯体のCo(I)種のプロトン還元能に着目し、新規な水素発生触媒の開発を行った。コバルト錯体としてはモノアニオン性の配位子であるイミン/オキシム型の二核コバルト錯体を用い、その二核中心の協同効果を利用した反応システムを構築した。

Event date： 2014.6

Language：English   Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2014.5

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Event date： 2014.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：名古屋大学   Country：Japan  

Event date： 2013.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：早稲田大学   Country：Japan  

Event date： 2013.11

Language：English   Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2013.11

Language：English   Presentation type：Oral presentation (general)  

Country：Taiwan, Province of China  

Event date： 2013.11

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：琉球大学   Country：Japan  

Event date： 2013.9

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：金沢大学   Country：Japan  

Event date： 2013.8

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.8

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：唐津   Country：Japan  

Event date： 2013.8

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：広島大学   Country：Japan  

Event date： 2013.6

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：神戸セミナーハウス   Country：Japan  

Event date： 2013.6

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.6

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.6

Language：English  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東北大学   Country：Japan  

Event date： 2012.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：同志社大学   Country：Japan  

Event date： 2012.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：沖縄   Country：Japan  

Event date： 2012.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：琉球大学   Country：Japan  

Event date： 2012.11

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：名古屋市立大学   Country：Japan  

Event date： 2012.11

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.10

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Event date： 2012.9

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：富山大学   Country：Japan  

Event date： 2012.9

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京工業大学   Country：Japan  

Event date： 2012.7

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：慶応大学   Country：Japan  

Event date： 2012.6

Language：English   Presentation type：Oral presentation (general)  

Venue：ルミエール府中   Country：Japan  

Event date： 2012.5

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：ベルサール神田   Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：アクトシテイ浜松   Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：慶応大学   Country：Japan  

Event date： 2011.11

Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.10

Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Event date： 2011.7

Venue：関西大学   Country：Japan  

表面ゾル-ゲル法を利用して、光に応答して水素を発生する触媒を開発した。

Event date： 2011.1

Presentation type：Oral presentation (general)  

Venue：鳥取   Country：Japan  

Event date： 2010.12

Presentation type：Oral presentation (general)  

Country：United States  

Catalysis of tetrapyrrole compound in inoic liquid was reported.

Event date： 2010.11

Presentation type：Oral presentation (general)  

Venue：福岡   Country：Japan  

Event date： 2010.11

Presentation type：Oral presentation (general)  

Country：Japan  

Photosensitization property of brominated porphycene was reported.

Event date： 2010.10

Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Hydrogen evolution and molecular transformation catalyzed by B12-TiO2 hybrid catalyst were reported.

Event date： 2010.9

Presentation type：Oral presentation (general)  

Venue：Osaka   Country：Japan  

Event date： 2010.9

Presentation type：Oral presentation (general)  

Country：Japan  

The light-driven B12 molecular transformation such as dechlorination of DDT was reported.

Event date： 2010.9

Presentation type：Oral presentation (general)  

Venue：千葉大学   Country：Japan  

Event date： 2010.6

Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2010.4

Presentation type：Oral presentation (general)  

Country：Canada  

The hybrid polymer was synthesized by a radical polymerization and its photocatalytic reaction was investigated.

Event date： 2009.11

Presentation type：Oral presentation (general)  

Country：Japan  

Recycled use of a porphycene having an ionic liquid tag in photosensitising oxidation of various substrate was achieved using an ionic liquid as reaction medium.

Event date： 2009.10

Presentation type：Oral presentation (general)  

Country：Austria  

B12-dependent enzymes, involving the cobalamin as a catalytic center, mediate various reactions.1 The CoI species of cobalamin derivative is widely known as a supernucleophile that forms an alkylated complex by reaction with an alkyl halide.2 The alkylated complex is a useful reagent for forming radical species as the cobalt-carbon bond is readily cleaved homolytically by photolysis, electrolysis, and thermolysis.3 Our research interest is focused on the application of this catalytic system to various molecular transformations. Recently, we reported dechlorination of DDT catalyzed by B12 derivative, heptamethyl cobrinate perchlorate, with a visible light irradiation system containing a [Ru(II)(bpy) 3]Cl2 photosensitizer as shown in Scheme 1.4 Although B12 derivative showed high catalytic efficiency in the reaction, large amount of photosensitizer was required for the reaction. To improve this problem, we synthesized new B12 catalyst having Ru(bpy)3 unit at peripheral position as shown in Chart 1. In this complex, photosensitizing unit was covalently bounded in cobalamin derivative, and which may allows efficient electron transfer from Ru(bpy)3 moiety to cobalt center of B12 moiety.

Event date： 2008.11

Presentation type：Oral presentation (general)  

Venue：福岡   Country：Japan  

Event date： 2008.9

Presentation type：Oral presentation (general)  

Country：Korea, Republic of  

Photophysical and photochemical properties of brominated porphycenes was investigated.

Event date： 2008.9

Presentation type：Oral presentation (general)  

Venue：金沢大学   Country：Japan  

Event date： 2008.6

Presentation type：Oral presentation (general)  

Venue：福岡   Country：Japan  

Event date： 2008.6

Presentation type：Oral presentation (general)  

Venue：近畿大学   Country：Japan  

Event date： 2007.9

Presentation type：Oral presentation (general)  

Venue：東北大学   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：新潟   Country：Japan  

Event date： 2018.7 - 2018.8

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.6

Language：English  

Country：Korea, Republic of  

Event date： 2015.5 - 2016.5

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Presentation type：Oral presentation (general)  

Venue：広島大学（広島）   Country：Japan  

Presentation type：Oral presentation (invited, special)  

Venue：立教大学（東京）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：立教大学（東京）   Country：Japan  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：九州大学（九州）   Country：Japan  

Presentation type：Oral presentation (general)  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：同志社大学（京都）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：高知大学（高知）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：神奈川大学（神奈川）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：大阪大学（大阪）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：長岡（新潟）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：北海道大学（北海道）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：北海道大学（北海道）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：埼玉工業大学（埼玉）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：立命館大学（滋賀）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：立命館大学（滋賀）   Country：Japan  

Presentation type：Oral presentation (general)  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：甲南大学（神戸）   Country：Japan  

Presentation type：Oral presentation (general)  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：京都   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：千葉大学（千葉）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：島根大学（島根）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：早稲田大学（東京）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：東北大学（仙台）   Country：Japan  

Presentation type：Oral presentation (general)  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：岡山大学（岡山）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：大阪大学（大阪）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：東京大学（東京）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：九州工業大学（福岡）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：早稲田大学（東京）   Country：Japan  

Presentation type：Oral presentation (invited, special)  

Venue：早稲田大学（東京）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：東京工業大学（東京）   Country：Japan  

Presentation type：Oral presentation (general)  

Country：Japan  

Presentation type：Oral presentation (general)  

Venue：北海道大学（北海道）   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：福岡   Country：Japan  

Presentation type：Oral presentation (general)  

Venue：山形大学（山形）   Country：Japan  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Type：Peer review 

Number of peer-reviewed articles in foreign language journals：3

Type：Competition, symposium, etc. 

Type：Scientific advice/Review 

Type：Scientific advice/Review 

Type：Peer review 

Number of peer-reviewed articles in Japanese journals：6

Type：Peer review 

Number of peer-reviewed articles in foreign language journals：6

Type：Competition, symposium, etc. 

Number of participants：80

Type：Academic society, research group, etc. 

Type：Peer review 

Number of peer-reviewed articles in foreign language journals：6

Type：Peer review 

Number of peer-reviewed articles in foreign language journals：8

Type：Competition, symposium, etc. 

Number of participants：50

Type：Competition, symposium, etc. 

Number of participants：80

Type：Competition, symposium, etc. 

Number of participants：2,000

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

researchmap

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

researchmap

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

researchmap

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

researchmap

Type：Competition, symposium, etc. 

Type：Competition, symposium, etc. 

researchmap