Faculty Profiles - FUJIHIRA HARUNA

Information

写真a

FUJIHIRA HARUNA

Organization

Faculty of Information Science and Electrical Engineering Department of Informatics Assistant Professor

Tel

0928023577

Profile

Fields: Auditory neurophysiology, Hearing loss, Aging, Hidden heraing loss, Auditory training, Autism spectrum disorder, Pupillary response Research topics: (1) The study on elderly listeners’ speech understanding under reverberation using auditory brainstem responses to speech (2) Auditory characteristics in people with autism spectrum disorder (3) Evaluation of hidden hearing loss by electrophysiological measures in human (4) Sensitivities of pupillary dilation responses to alert sounds (5) Development of auditory training program

Homepage

https://researchmap.jp/haruna_fujihira
Researcmap

External link

Research Areas

Life Science / Cognitive and brain science
Life Science / Otorhinolaryngology
Informatics / Perceptual information processing
Humanities & Social Sciences / Experimental psychology

Degree

Ph.D (Design)

Research History

NTTコミュニケーション科学基礎研究所

Research Interests・Research Keywords

Research theme：音源定位

Keyword：音源定位

Research period： 2026
Research theme：難聴

Keyword：難聴

Research period： 2026
Research theme：隠れ難聴

Keyword：隠れ難聴

Research period： 2026
Research theme： Cochlear synaptopathy

Keyword： Cochlear synaptopathy

Research period： 2026
Research theme：脳幹

Keyword：脳幹

Research period： 2026
Research theme：聴覚訓練

Keyword：聴覚訓練

Research period： 2026
Research theme：聴覚

Keyword：聴覚

Research period： 2026
Research theme：神経発達症

Keyword：神経発達症

Research period： 2026
Research theme：神経生理学

Keyword：神経生理学

Research period： 2026
Research theme：瞳孔反応

Keyword：瞳孔反応

Research period： 2026
Research theme：注意

Keyword：注意

Research period： 2026
Research theme：心理物理学

Keyword：心理物理学

Research period： 2026
Research theme： Development of auditory training program

Keyword： Auditory trainig, Application, Auditory brainstem response

Research period： 2023.4 - 2025.3
Research theme： Evaluation of hidden hearing loss by electrophysiological measures in human

Keyword： Hidden hearing loss, Electrophysiological measure, Paired-click stimulus

Research period： 2022.4 - 2025.3
Research theme： Auditory characteristics in people with autism spectrum disorder

Keyword： Autism spectrum disorder, Auditory brainstem response, Interaural time difference, Interaural level difference

Research period： 2020.4 - 2023.3
Research theme： Sensitivities of pupillary dilation responses to alert sounds

Keyword： Pupillary response, Attention, Alert sound

Research period： 2017.4 - 2020.3
Research theme： The study on hearing aids using auditory brainstem responses to speech in elderly people

Keyword： Aging, Auditory brainstem response, Speech

Research period： 2015.4 - 2017.3

Awards

第38回2015年春季研究発表会日本音響学会粟屋潔学術奨励賞

2015.3
第7回2013年春季研究発表会日本音響学会学生優秀発表賞

2013.3
平成25年度九州大学芸術工学部・大学院芸術工学府学生表彰

2013.3
2010年度日本音響学会九州支部学生表彰

2010.3

Papers

Altered Paired-Click Auditory Brainstem Responses in Normal-Hearing Young Adults With Frequent Loud Sound Exposure Reviewed

Haruna Fujihira, Rinako Higashi, Shimpei Yamagishi, Shigeto Furukawa, Makio Kashino, Shuji Mori

Trends in Hearing 30 23312165261417086 2026 （ ISSN:2331-2165 eISSN:2331-2165 ）

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Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：SAGE Publications

This study investigated differences in auditory brainstem responses (ABRs) using the paired-click paradigm between young adults frequently exposed to loud sounds and those not. Young adults with normal hearing were divided into two groups: an exposed group (n = 23), who were frequently exposed to loud sounds through music practice, and a control group (n = 21). Sound exposure levels (measured via smartwatch), hearing thresholds (0.125–16 kHz), distortion product otoacoustic emission (DPOAE) magnitudes, word intelligibility, and ABRs to single and paired clicks were obtained. For paired-click ABRs, root mean square values for the post-wave I response delayed from the wave I peak (RMS <sub>post-w1</sub> ) were calculated for second-click responses. The exposed group exhibited higher sound exposure levels than the control group. Despite similar hearing thresholds, DPOAE magnitudes, wave I peak amplitudes and wave I/V amplitude ratio, the exposed group showed significantly lower RMS <sub>post-w1</sub> values for second-click responses than the control group. No significant group difference was observed in word intelligibility. The results showed that frequent loud sound exposure may induce peripheral auditory changes consistent with cochlear synaptopathy (CS). This suggests that the paired-click stimulation paradigm may offer a way of detecting noise-induced CS.

File： Fujihira(2026)_Altered-paired-click-auditory-brainstem-responses-in-normal-hearing-young-adults-with-frequent-loud.pdf

DOI： 10.1177/23312165261417086

Web of Science

PubMed

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Other Link： https://journals.sagepub.com/doi/full-xml/10.1177/23312165261417086
Auditory brainstem response to paired clicks as a candidate marker of cochlear synaptopathy in humans Reviewed

Fujihira Haruna, Yamagishi Shimpei, Furukawa Shigeto, Kashino Makio

Clinical Neurophysiology 165 44 - 54 2024.6 （ ISSN:13882457 eISSN:18728952 ）

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Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier

Objective: This study aimed to evaluate whether auditory brainstem response (ABR) using a paired-click stimulation paradigm could serve as a tool for detecting cochlear synaptopathy (CS). / Methods: The ABRs to single-clicks and paired-clicks with various inter-click intervals (ICIs) and scores for word intelligibility in degraded listening conditions were obtained from 57 adults with normal hearing. The wave I peak amplitude and root mean square values for the post-wave I response within a range delayed from the wave I peak (referred to as the RMSpost-w1) were calculated for the single- and secondclick responses. / Results: The wave I peak amplitudes did not correlate with age except for the second-click responses at an ICI of 7 ms, and the word intelligibility scores. However, we found that the RMSpost-w1 values for the second-click responses significantly decreased with increasing age. Moreover, the RMSpost-w1 values for the second-click responses at an ICI of 5 ms correlated significantly with the scores for word intelligibility in degraded listening conditions. / Conclusions: The magnitude of the post-wave I response for the second-click response could serve as a tool for detecting CS in humans. / Significance: Our findings shed new light on the analytical methods of ABR for quantifying CS.

CiNii Research
Sensitivity to interaural level and time differences in individuals with autism spectrum disorder. Reviewed International journal

Haruna Fujihira, Chihiro Itoi, Shigeto Furukawa, Nobumasa Kato, Makio Kashino

Scientific reports 12 ( 1 ) 19142 - 19142 2022.11 （ eISSN:2045-2322 ）

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Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Scientific Reports

Individuals with autism spectrum disorders (ASD) are reported to exhibit degraded performance in sound localization. This study investigated whether the sensitivity to the interaural level differences (ILDs) and interaural time differences (ITDs), major cues for horizontal sound localization, are affected in ASD. Thresholds for discriminating the ILD and ITD were measured for adults with ASD and age- and IQ-matched controls in a lateralization experiment. Results show that the ASD group exhibited higher ILD and ITD thresholds than the control group. Moreover, there was a significant diversity of ITD sensitivity in the ASD group, and it contained a larger proportion of participants with poor ITD sensitivity than the control group. The current study suggests that deficits in relatively low-level processes in the auditory pathway are implicated in degraded performance of sound localization in individuals with ASD. The results are consistent with the structural abnormalities and great variability in the morphology in the brainstem reported by neuroanatomical studies of ASD.

DOI： 10.1038/s41598-022-23346-y

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Repository Public URL： https://hdl.handle.net/2324/7178608
Auditory brainstem responses in adults with autism spectrum disorder Reviewed

H. Fujihira, C. Itoi, S. Furukawa, N. Kato, M. Kashino

Clinical Neurophysiology Practice 6 179 - 184 2021.1

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Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal)

Objective: To investigate possible differences in the auditory peripheral and brainstem functions between adults with autism spectrum disorder (ASD) and neurotypical (NT) adults. Methods: Click-evoked auditory brainstem responses (ABRs) were obtained from 17 high-functioning ASD adults (aged 21–38 years) and 20 NT adults (aged 22–36 years). A relatively large number of stimulus presentations (6000) were adopted, and ABRs by horizontal and vertical electrode montages were evaluated, in order to allow precise evaluations of early ABR components. Results: Waves I, II, III, and V were identified in the vertical electrode montage, and wave I and the summating potential (SP) in electrocochleograms were identified in the horizontal electrode montage. There were no significant group differences in the wave I, II, III, and V latencies or the interpeak latencies (IPLs) in the vertical electrode montage. In the horizontal montage, the ASD adults exhibited significantly shortened SP latencies compared with the NT adults, whereas there was no significant group difference in the wave I latency. Conclusion: The ASD adults may have the abnormalities of processing more in the peripheral auditory system than in the brainstem. Significance: The current study suggests that the peripheral abnormality is associated with ASD.

DOI： 10.1016/j.cnp.2021.04.004

Repository Public URL： https://hdl.handle.net/2324/7178609
Correlations between word intelligibility under reverberation and speech auditory brainstem responses in elderly listeners Reviewed International journal

H. Fujihira, K. Shiraishi

Clinical Neurophysiology 126 ( 1 ) 96 - 102 2015.1

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Language：English Publishing type：Research paper (scientific journal)

Objective: To investigate the relationship between speech auditory brainstem responses (speech ABRs) and word intelligibility under reverberation in elderly adults. Methods: Word intelligibility for words under four reverberation times (RTs) of 0, 0.5, 1.0, 1.5. s, and speech ABRs to the speech syllable/da/ were obtained from 30 elderly listeners. Root mean square (RMS) amplitudes and discrete Fourier transform (DFT) amplitudes were calculated for ADD and SUB responses in the speech ABRs. Results: No significant correlations were found between the word intelligibility scores under reverberation and the ADD response components. However, in the SUB responses we found that the DFT amplitudes associated with H4-SUB, H5-SUB, H8-SUB, H9-SUB and H10-SUB significantly correlated with the word intelligibility scores for words under reverberation. With Bonferroni correction, the DFT amplitudes for H5-SUB and the intelligibility scores for words with the RT of 0.5s and 1.5s were significant. Conclusions: Word intelligibility under reverberation in elderly listeners is related to their ability to encode the temporal fine structure of speech. Significance: The results expand knowledge about subcortical responses of elderly listeners in daily-life listening situations. The SUB responses of speech ABR could be useful as an objective indicator to predict word intelligibility under reverberation.

DOI： 10.1016/j.clinph.2014.05.001

Repository Public URL： https://hdl.handle.net/2324/7174373
Cochlear synaptopathy and its assessment Invited

Fujihira Haruna

THE JOURNAL OF THE ACOUSTICAL SOCIETY OF JAPAN 81 ( 5 ) 332 - 337 2025.5 （ ISSN:03694232 eISSN:24322040 ）

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Authorship：Lead author Language：Japanese Publishing type：Research paper (conference, symposium, etc.) Publisher：Acoustical Society of Japan

DOI： 10.20697/jasj.81.5_332

CiNii Research
Seeing an Auditory Object: Pupillary Light Response Reflects Covert Attention to Auditory Space and Object. Reviewed International journal

Hsin-I Liao, Haruna Fujihira, Shimpei Yamagishi, Yung-Hao Yang, Shigeto Furukawa

Journal of cognitive neuroscience 35 ( 2 ) 276 - 290 2023.2 （ ISSN:0898-929X eISSN:1530-8898 ）

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Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Cognitive Neuroscience

Attention to the relevant object and space is the brain's strategy to effectively process the information of interest in complex environments with limited neural resources. Numerous studies have documented how attention is allocated in the visual domain, whereas the nature of attention in the auditory domain has been much less explored. Here, we show that the pupillary light response can serve as a physiological index of auditory attentional shift and can be used to probe the relationship between space-based and object-based attention as well. Experiments demonstrated that the pupillary response corresponds to the luminance condition where the attended auditory object (e.g., spoken sentence) was located, regardless of whether attention was directed by a spatial (left or right) or nonspatial (e.g., the gender of the talker) cue and regardless of whether the sound was presented via headphones or loudspeakers. These effects on the pupillary light response could not be accounted for as a consequence of small (although observable) biases in gaze position drifting. The overall results imply a unified audiovisual representation of spatial attention. Auditory object-based attention contains the space representation of the attended auditory object, even when the object is oriented without explicit spatial guidance.

DOI： 10.1162/jocn_a_01935

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Repository Public URL： https://hdl.handle.net/2324/7178611
Elderly listeners with low intelligibility scores under reverberation show degraded subcortical representation of reverberant speech Reviewed

H. Fujihira, K. Shiraishi, G. B. Remijn

Neuroscience Letters 637 102 - 107 2017.1

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In order to elucidate why many elderly listeners have difficulty understanding speech under reverberation, we investigated the relationship between word intelligibility and auditory brainstem responses (ABRs) in 28 elderly listeners. We hypothesized that the elderly listeners with low word intelligibility scores under reverberation would show degraded subcortical encoding information of reverberant speech as expressed in their ABRs towards a reverberant /da/ syllable. The participants were divided into two groups (top and bottom performance groups) according to their word intelligibility scores for anechoic and reverberant words, and ABR characteristics between groups were compared. We found that correlation coefficients between responses to anechoic and reverberant /da/ were lower in the bottom performance group than in the top performance group. This result suggests that degraded neural representation toward information of reverberant speech may account for lower intelligibility of reverberant speech in elderly listeners.

DOI： 10.1016/j.neulet.2016.11.042

Repository Public URL： https://hdl.handle.net/2324/7178610
An introduction to the measurement of auditory event-related potentials (ERPs) Reviewed

Gerard B. Remijn, Emi Hasuo, Haruna Fujihira, Satoshi Morimoto

Acoustical Science and Technology 35 ( 5 ) 229 - 242 2014

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Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1250/ast.35.229

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Presentations

Paired-click刺激法を用いた聴性脳幹反応による蝸牛シナプス障害指標の検討－ヒトデータに基づく評価と生理学的考察－

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会聴覚研究会 2026.5

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Event date： 2026.5

Language：Japanese Presentation type：Oral presentation (general)

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Assessment of human cochlear synaptopathy using auditory brainstem responses to paired-click stimuli

Haruna Fujihira, Rinako Higashi, Shimpei Yamagishi, Shigeto Furukawa, Makio Kashino, Shuji Mori

Sixth Joint Meeting Acoustical Society of America and Acoustical Society of Japan 2025.12

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Event date： 2025.12

Language：English Presentation type：Poster presentation

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Sensitivities to Interaural Level and Time Differences in Adults with Listening Difficulties

Erina S. ONOE, Kazuaki HONDA, Chihiro ITOI, Shimpei YAMAGISHI, Haruna FUJIHIRA, Makio KASHINO

Sixth Joint Meeting Acoustical Society of America and Acoustical Society of Japan 2025.12

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Event date： 2025.12

Language：English Presentation type：Poster presentation

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Paired-click 刺激法を用いた聴性脳幹反応による蝸牛シナプス障害の評価

藤平晴奈, 古川茂人, 柏野牧夫, 森周司

第70回日本聴覚医学会総会・学術講演会 2025.10

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Event date： 2025.10

Language：Japanese Presentation type：Oral presentation (general)

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音楽練習における強大音暴露による蝸牛シナプス障害の可能性－Paired-click刺激法を用いた聴性脳幹反応による検証－

藤平晴奈, 東莉奈子, 山岸慎平, 古川茂人, 柏野牧夫, 森周司

日本音響学会秋季研究発表会 2025.9

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Event date： 2025.9

Language：Japanese Presentation type：Oral presentation (general)

File： CDからの原稿_1-2-10_0110.pdf

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The relationship of between-ear attentional transitions with otoacoustic emissions

Madoka Matsuge, Yuki Ishizka, Shimpei Yamagishi, Haruna Fujihira, Sho Otsuka, Shigeto Furukawa, Seiji Nakagawa

48th ARO Midwinter Meeting 2025.2

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Event date： 2025.2

Language：English Presentation type：Poster presentation

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聞き取り困難症・聴覚情報処理障害（LiD/APD）における両耳間レベル差・時間差の検討

尾上恵里奈, 本田一暁, 糸井千尋, 山岸慎平, 藤平晴奈, 柏野牧夫

日本音響学会聴覚研究会 2025.2

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Event date： 2025.1 - 2025.2

Language：Japanese Presentation type：Oral presentation (general)

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快適な補聴器装用を目指した聴覚訓練アプリの使用感調査－補聴器サービス従事者を対象とした検討－

岩本沙也, 岡本潔和, 西元克茂, 竹松知紀, 飛松葉子, 石橋るみ, 田島康宇, 越智亮太, 藤平晴奈, 森周司

日本音響学会聴覚研究会 2024.11

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Event date： 2024.11

Language：Japanese Presentation type：Poster presentation

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聴覚機能の改善を目指した訓練アプリの開発および使用感調査

藤平晴奈, 西元克茂, 竹松知紀, 飛松葉子, 石橋るみ, 田島康宇, 森周司

第69回日本聴覚医学会総会・学術講演会 2024.10

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Event date： 2024.10

Language：Japanese Presentation type：Oral presentation (general)

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Paired-click刺激法による蝸牛シナプス障害の評価と拡張高周波数帯の聴力閾値との関連性

藤平晴奈，山岸慎平，古川茂人，柏野牧夫

日本音響学会2023年秋季研究発表会 2023.9

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Event date： 2024.9 - 2023.4

Language：Japanese

Venue：名古屋工業大 Country：Japan

Repository Public URL： https://hdl.handle.net/2324/7178602
左右耳への外因的注意が耳音響放射に与える影響

松毛円佳, 石坂勇毅, 山岸慎平, 藤平晴奈, 大塚翔, 古川茂人, 中川誠司

日本音響学会秋季研究発表会 2024.9

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Event date： 2024.9

Language：Japanese Presentation type：Poster presentation

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聴覚機能の改善を目指した訓練アプリの開発および使用感調査－認知機能に関する検討－

藤平晴奈, 岡本潔和, 岩本沙也, 西元克茂, 竹松知紀, 飛松葉子, 石橋るみ, 田島康宇, 越智亮太, 森周司

日本音響学会秋季研究発表会 2024.9

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Event date： 2024.9

Language：Japanese Presentation type：Poster presentation

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聴覚機能の改善を目指した訓練アプリの開発および使用感調査 ―聴覚処理能力に関する検討―

岩本沙也, 西元克茂, 竹松知紀, 飛松葉子, 石橋るみ, 田島康宇, 越智亮太, 藤平晴奈, 森周司

日本音響学会秋季研究発表会 2024.9

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Event date： 2024.9

Language：Japanese Presentation type：Poster presentation

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自閉スペクトラム症者における共変調マスキング解除

藤平晴奈、古川茂人、柏野牧夫

第68回日本聴覚医学会総会・学術講演会 2023.10

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Event date： 2023.10

Language：Japanese Presentation type：Oral presentation (general)

Venue：千葉　幕張メッセ　国際会議場 Country：Japan
自閉スペクトラム症者における共変調マスキング解除

藤平晴奈, 古川茂人, 柏野牧夫

第68回日本聴覚医学会総会・学術講演会 2023.10

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Event date： 2023.10

Language：Japanese Presentation type：Oral presentation (general)

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Paired-click 刺激法による蝸牛シナプス障害の評価と拡張高周波数帯の聴力閾値との関連性

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会秋季研究発表会 2023.9

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Event date： 2023.9

Language：Japanese Presentation type：Poster presentation

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聴覚の空間的注意が耳音響放射に与える影響

石坂勇毅, 大塚翔, 山岸慎平, 藤平晴奈, 古川茂人, 中川誠司

日本音響学会聴覚研究会 2023.5

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Event date： 2023.5

Language：Japanese Presentation type：Oral presentation (general)

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Paired-click刺激法による蝸牛シナプス障害の評価―ヒトの蝸牛神経複合活動電位による検討―

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会春季研究発表会 2023.3

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Event date： 2023.3

Language：Japanese Presentation type：Poster presentation

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Paired-click刺激法による蝸牛シナプス障害の評価―計算機シミュレーションによる検討―

山岸慎平, 藤平晴奈, 古川茂人, 柏野牧夫

日本音響学会春季研究発表会 2023.3

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Event date： 2023.3

Language：Japanese Presentation type：Poster presentation

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蝸牛シナプス障害の評価に向けたpaired-click刺激に対する蝸牛神経応答の計算機シミュレーション

山岸慎平, 藤平晴奈, 古川茂人, 柏野牧夫

日本音響学会聴覚研究会 2023.1

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Event date： 2023.1

Language：Japanese Presentation type：Oral presentation (general)

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From viewpoint of Electrophysiology: Auditory brainstem response to paired click stimulation as a marker of cochlear synaptopathy in human Invited

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

内耳ひずみ研究会 2022.12

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Event date： 2022.12

Language：Japanese Presentation type：Oral presentation (invited, special)

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ヒトを対象としたpaired-click刺激に対する蝸牛神経複合活動電位によるcochlear synaptopathyの評価

藤平晴奈, 古川茂人, 柏野牧夫

第67回日本聴覚医学会総会・学術講演会 2022.10

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Event date： 2022.10

Language：Japanese Presentation type：Oral presentation (general)

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両耳間位相差刺激に対する脳幹誘発電位の両耳相互作用

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会秋季研究発表会 2022.9

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Event date： 2022.9

Language：Japanese Presentation type：Poster presentation

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Paired-click 刺激に対する蝸牛神経複合活動電位によるcochlear synaptopathy の評価―若年者と中年者を対象とした予備的検討―

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

第2回ERA・ERP研究会 2022.7

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Event date： 2022.7

Language：Japanese Presentation type：Oral presentation (general)

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対クリック刺激法による蝸牛シナプトパシーの他覚的評価の予備的検討

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会聴覚研究会 2022.5

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Event date： 2022.5

Language：Japanese Presentation type：Oral presentation (general)

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両耳間位相差刺激に対する脳幹/皮質誘発電位と知覚感度との関連性

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会春季研究発表会 2022.3

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Event date： 2022.3

Language：Japanese Presentation type：Poster presentation

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音声刺激に対する聴性脳幹反応の加算回数に関する検討

白石君男, 泉春名, 内田匠, 藤平晴奈

第11回ERA・OAE研究会 2016.7

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Event date： 2016.7

Language：Japanese Presentation type：Oral presentation (general)

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Effects of reverberation on auditory brainstem responses (ABRs) to speech in elderly listeners International conference

Haruna Fujihira, Kimio Shiraishi, Gerard B. Remijn

XXIV Biennial Symposium of the International Evoked Response Audiometry Study Group (IERASG) 2015.5

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Event date： 2015.5

Language：English

Country：Korea, Republic of
Duration perception of filled and empty intervals - a study with magnitude estimation and electroencephalography International conference

Emi Hasuo, Kazuo Ueda, Takuya Kishida, Haruna Fujihira, Satoshi Morimoto, Gerard Remijn, Kimio Shiraishi, Shozo Tobimatsu, Yoshitaka Nakajima

13th International Conference on Music Perception and Cognition 2014.10

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Event date： 2014.10

Language：English Presentation type：Oral presentation (general)

Venue：Seoul (Korea) Country：Korea, Republic of
Brain stem responses to reverberant speech in elderly listeners International conference

@Haruna Fujihira, @Kimio Shiraishi

XXXII World Congress of Audiology 2014.5

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Event date： 2014.5

Language：English

Venue：Brisbane (Australia) Country：Australia
Effectiveness of a hearing loop (magnetic induction) system in a bus for elderly people International conference

@Kimio Shiraishi, @Haruna Fujihira

XXXII World Congress of Audiology 2014.4

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Event date： 2014.4

Language：English

Venue：Brisbane (Australia) Country：Australia
Paired-click刺激法による蝸牛シナプス障害の評価-ヒトの蝸牛神経複合活動電位による検討-

藤平晴奈, 藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2023.3

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Country：Japan

Evaluation of cochlear synaptopathy by paired-click stimulus-Assessing the action potential in human-
自閉スペクトラム症者における共変調マスキング解除

藤平晴奈, 古川茂人, 柏野牧夫

Audiology Japan 2023.9 (一社)日本聴覚医学会

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ヒトを対象としたpaired-click刺激に対する蝸牛神経複合活動電位によるcochlear synaptopathyの評価

藤平晴奈, 古川茂人, 柏野牧夫

Audiology Japan 2022.9 (一社)日本聴覚医学会

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聴覚機能の改善を目指した訓練アプリの開発および使用感調査

藤平晴奈, 西元克茂, 竹松知紀, 飛松葉子, 石橋るみ, 田島康宇, 森周司

Audiology Japan 2024.9 (一社)日本聴覚医学会

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Paired-click刺激法を用いた聴性脳幹反応による蝸牛シナプス障害の評価

藤平晴奈, 古川茂人, 柏野牧夫, 森周司

Audiology Japan 2025.9 (一社)日本聴覚医学会

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MISC

小特集—加齢性難聴の研究の新しい展開— 蝸牛シナプス障害とその評価手法 Invited

藤平晴奈

日本音響学会誌 81 ( 5 ) 332 - 337 2025.5

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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)

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聞き取り困難症・聴覚情報処理障害(LiD/APD)における両耳間レベル差・時間差の検討—Evaluation of Interaural Level and Time Difference in Adults with Listening Difficulties and Auditory Processing Disorder

尾上恵里奈, 本田一暁, 糸井千尋, 山岸慎平, 藤平晴奈, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 55 ( 1 ) 45 - 50 2025 （ ISSN:1346-1109 ）

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Language：Japanese Publisher：東京 : 日本音響学会

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Other Link： https://ndlsearch.ndl.go.jp/books/R000000004-I033949223
Effect of exogenous attention to left and right ears on otoacoustic emissions

松毛円佳, 石坂勇毅, 山岸慎平, 藤平晴奈, 大塚翔, 古川茂人, 古川茂人, 古川茂人, 中川誠司

日本音響学会研究発表会講演論文集(CD-ROM) 2024 2024 （ ISSN:1880-7658 ）

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聴覚の空間的注意が耳音響放射に与える影響—The Effect of Auditory-Spatial Attention on Otoacoustic Emission

石坂勇毅, 山岸慎平, 藤平晴奈, 大塚翔, 古川茂人, 中川誠司

聴覚研究会資料 = Proceedings of the auditory research meeting 53 ( 3 ) 63 - 68 2023.5 （ ISSN:1346-1109 ）

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聴覚の空間的注意が耳音響放射に与える影響—The Effect of Auditory-Spatial Attention on Otoacoustic Emission

石坂勇毅, 山岸慎平, 藤平晴奈, 大塚翔, 古川茂人, 中川誠司

聴覚研究会資料 = Proceedings of the auditory research meeting 2023.5

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Evaluation of cochlear synaptopathy by paired-click stimulus-Assessing the action potential in human-

藤平晴奈, 藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2023 2023.3 （ ISSN:1880-7658 ）

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蝸牛シナプス障害の評価に向けたpaired-click刺激に対する蝸牛神経応答の計算機シミュレーション—Computer simulation of cochlear nerve responses to paired-click stimulation toward the evaluation of cochlear synaptopathy

山岸慎平, 藤平晴奈, 古川茂人, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 53 ( 1 ) 7 - 11 2023.1 （ ISSN:1346-1109 ）

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蝸牛シナプス障害の評価に向けたpaired-click刺激に対する蝸牛神経応答の計算機シミュレーション—Computer simulation of cochlear nerve responses to paired-click stimulation toward the evaluation of cochlear synaptopathy

山岸慎平, 藤平晴奈, 古川茂人, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 2023.1

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自閉スペクトラム症者における共変調マスキング解除

藤平晴奈, 藤平晴奈, 古川茂人, 古川茂人, 古川茂人, 柏野牧夫

Audiology Japan 66 ( 5 ) 2023 （ ISSN:0303-8106 ）

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Relationship between extended high-frequency hearing thresholds and electrophysiological measures using paired-click stimulation as a marker of cochlear synaptopathy.

藤平晴奈, 藤平晴奈, 山岸慎平, 古川茂人, 古川茂人, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2023 2023 （ ISSN:1880-7658 ）

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Evaluation of cochlear synaptopathy by paired-click stimulus-A study using computer simulation

山岸慎平, 藤平晴奈, 藤平晴奈, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2023 2023 （ ISSN:1880-7658 ）

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ヒトを対象とした paired-click 刺激に対する蝸牛神経複合活動電位による cochlear synaptopathy の評価

藤平晴奈, 古川茂人, 柏野牧夫

ＡＵＤＩＯＬＯＧＹＪＡＰＡＮ 65 ( 5 ) 423 - 423 2022.9 （ ISSN:0303-8106 eISSN:1883-7301 ）

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Language：Japanese Publisher：一般社団法人日本聴覚医学会

DOI： 10.4295/audiology.65.423

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対クリック刺激法による蝸牛シナプトパシーの他覚的評価の予備的検討—A preliminary study of objective evaluation of cochlear synaptopathy using paired click stimulation paradigm

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 52 ( 3 ) 203 - 208 2022.5 （ ISSN:1346-1109 ）

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対クリック刺激法による蝸牛シナプトパシーの他覚的評価の予備的検討—A preliminary study of objective evaluation of cochlear synaptopathy using paired click stimulation paradigm

藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 2022.5

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Binaural interaction of brainstem responses to interaural phase modulation sound

藤平晴奈, 藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2022 2022 （ ISSN:1880-7658 ）

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Frequency following response correlates with interaural phase modulation following response and behavioural performance

藤平晴奈, 藤平晴奈, 山岸慎平, 古川茂人, 柏野牧夫

日本音響学会研究発表会講演論文集(CD-ROM) 2022 2022 （ ISSN:1880-7658 ）

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自閉スペクトラム症者の両耳間時間差および両耳間レベル差の弁別閾と聴性脳幹反応—Sensitivity to interaural time and level differences and auditory brainstem responses in individuals with autism spectrum disorder

藤平晴奈, 糸井千尋, 古川茂人, 加藤進昌, 柏野牧夫

聴覚研究会資料 = Proceedings of the auditory research meeting 2021.5

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成人の自閉スペクトラム症者における聴性脳幹反応

藤平晴奈, 古川茂人, 柏野牧夫

ＡＵＤＩＯＬＯＧＹＪＡＰＡＮ 2020.9

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DOI： 10.4295/audiology.63.435
2 音節音声による聴性脳幹反応を用いた高齢者の他覚的な聴覚評価―聴取成績との関連性

藤平晴奈, 白石君男

ＡＵＤＩＯＬＯＧＹＪＡＰＡＮ 2018.9

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DOI： 10.4295/audiology.61.313
聴覚末梢の障害に着目した電気生理学的手法による耳鳴りの客観的評価の検討—Objective evaluation of subjective tinnitus using electrophysiological method considering deficits of peripheral auditory system

藤平晴奈, 白石君男

聴覚研究会資料 = Proceedings of the auditory research meeting 2018.5

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刺激音出現頻度が聴性脳幹反応に及ぼす影響—Effect of probability of stimuli on frequency following responses

大塚翔, 藤平晴奈, 山岸慎平, 古川茂人

聴覚研究会資料 = Proceedings of the auditory research meeting 2017.6

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対話型差分進化を用いた耳鳴音探索システムの基礎的検討

木下, 光太郎, 白石, 君男, 藤平, 晴奈, 高木, 英行, 齋藤, 睦巳

聴覚研究会資料 2016.3

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A Study on Measurement of Tinnitus Using Interactive Differential Evolution
音声刺激に対する聴性脳幹反応における若年者と高齢者の比較—Comparison of auditory brainstem responses to speech sounds between young and elderly adults

藤平晴奈, 白石君男

聴覚研究会資料 = Proceedings of the auditory research meeting 2013.6

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音声刺激に対する聴性脳幹反応における若年者と高齢者の比較—Comparison of auditory brainstem responses to speech sounds between young and elderly adults

藤平晴奈, 白石君男

電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 2013.6

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音の立ち上がり･立ち下がりに対する聴性緩反応—The slow vertex responses to onset and offset of sound

藤平晴奈, 白石君男, Gerard B. REMIJN

聴覚研究会資料 = Proceedings of the auditory research meeting 2011.12

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Industrial property rights

Patent	Number of applications: 1	Number of registrations: 1
Utility model	Number of applications: 0	Number of registrations: 0
Design	Number of applications: 0	Number of registrations: 0
Trademark	Number of applications: 0	Number of registrations: 0

Professional Memberships

日本聴覚医学会
日本音響学会
米国耳鼻咽喉科学会
米国耳鼻咽喉科学会

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日本音響学会

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日本聴覚医学会

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Committee Memberships

日本音響学会聴覚研究会幹事

2024.4 - Present

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Research Projects

難聴の早期発見に向けた耳年齢モデルの基盤構築：蝸牛シナプス障害検出法の評価

Grant number：26K14882 2026.4 - 2029.3

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

藤平晴奈, WONG WILLY

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Grant type：Scientific research funding

世界的な高齢化に伴い難聴者は増加しており、認知症リスクや生活の質の低下、医療費増大を招く深刻な社会問題となっている。これを抑制するには早期発見と予防が不可欠であり、初期病態の把握が重要である。近年、難聴初期に蝸牛シナプス障害が生じることが示されている。申請者は、この障害を検出する手法として、対クリック刺激による聴性脳幹反応測定法を考案し、その指標が加齢変化を反映することを示した。本研究では、指標の感度・再現性を検証し、性別や音響暴露歴との関連を明らかにした上で、難聴の初期障害の程度を年齢換算で推定する「耳年齢」モデルの基盤構築と精度向上を目指す。

CiNii Research
Comprehensive approach to human auditory temporal resolution -theory, brain function analysis, testing, training-

Grant number：24H00174 2024.4 - 2028.3

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

森周司, 岡本康秀, 小渕千絵, 岡本秀彦, 神崎晶, 藤平晴奈, 山本弥生

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音の時間変化を検知する能力、即ち時間分解能は音声知覚に必須の機能である。ヒト聴覚の時間分解能は鋭敏で聴覚末梢系の処理を反映すると考えられてきたが、近年矛盾する結果が出ており、新たな理論や神経基盤の解明が待たれている。時間分解能の低下は聴覚障害の一因となるが、耳鼻咽喉科の検査項目に時間分解能は含められておらず、診断や治療を妨げている。聴覚障害による死亡率の増加と莫大な経済損失は重大な社会的問題であり、診療用の時間分解能検査の確立と低下改善手法の開発が早急に望まれる。本研究では、基礎から臨床までの聴覚時間分解能の課題に対し、理論、脳機能計測、検査、聴覚訓練の研究を連携して取り組む。

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聴覚訓練用アプリの開発とその効果の検証

2024.4 - 2025.3

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公益信託小野音響学研究助成基金による助成金によりプロジェクトを実施
補聴器装用のための聴覚訓練システムの開発

2024.2 - 2025.3

Joint research

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補聴器装用のための聴覚訓練システムの開発とその訓練効果に関する研究

2023.8 - 2024.8

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一般財団法人曽田豊二記念財団 2023年度耳鼻咽喉科及び関連分野の研究に対する助成金
様々な聞こえの困難を同定するための聴覚初期情報処理の検査手法に関する研究

2023.7 - 2024.2

Joint research

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ヒトを対象としたpaired-click刺激に対する蝸牛神経複合活動電位によるcochlear synaptopathyの評価

2022.4 - 2025.3

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科学研究費若手研究
Elucidating the mechanisms underlying hidden hearing loss through cochlear nerve responses in humans

Grant number：22K17924 2022 - 2024

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Early-Career Scientists

Fujihira Haruna

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Authorship：Principal investigator Grant type：Scientific research funding

Hidden hearing loss refers to a condition in which individuals exhibit normal hearing thresholds but experience difficulty understanding speech in the presence of background noise and/or reverberation. The present study aimed to elucidate the mechanisms underlying hidden hearing loss, with a particular focus on cochlear synaptopathy-a disorder affecting the synapses between inner hair cells and cochlear nerve fibers in the cochlea-which is considered a major contributing factor. Currently, there is no established method for detecting cochlear synaptopathy in humans. Therefore, considering the properties of cochlear nerve fibers affected by cochlear synaptopathy, we proposed auditory brainstem responses (ABRs) using a paired-click stimulation paradigm as an index that could reflect cochlear synaptopathy. Our findings demonstrate a significant association between the ABR indices and word intelligibility scores under noisy and reverberant listening conditions.

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聴性脳幹反応を用いた自閉スぺクトラム症と脳幹機能との関連に関する研究

Grant number：20J40247 2020 - 2023

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows

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高齢者の音声に対する聴性脳幹反応による新たな聴覚補償に関する研究

Grant number：15J07390 2015 - 2017

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows

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Class subject

プログラミング演習(P)

2024.6 - 2024.8 Summer quarter

FD Participation

2023.11 Role：Participation Title：【シス情FD】企業等との共同研究の実施増加に向けて

Organizer：[Undergraduate school/graduate school/graduate faculty]
2023.11 Role：Participation Title：GakuNin RDMデータ活用セミナー：これからの研究データ管理を探る

Organizer：[Undergraduate school/graduate school/graduate faculty]
2023.9 Role：Participation Title：【シス情FD】Top10%論文／Top10%ジャーナルとは何か: 傾向と対策

Organizer：[Undergraduate school/graduate school/graduate faculty]
2023.6 Role：Participation Title：【シス情FD】SBRC、QRECの活動ご紹介

Organizer：[Undergraduate school/graduate school/graduate faculty]
2023.4 Role：Participation Title：【シス情FD】若手教員による研究紹介⑧

Organizer：[Undergraduate school/graduate school/graduate faculty]
2023.4 Role：Participation Title：令和５年度第１回全学ＦＤ（新任教員の研修）The 1st All-University FD (training for new faculty members) in FY2023

Organizer：University-wide

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Social Activities

聴こえとともに元気に

Role(s)：Informant

九州大学 2025年度九州大学オープンキャンパス 2025.8

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音響性難聴の早期発見手法の開発

Role(s)：Advisor

伊藤早苗記念基金事業令和６年度九州大学QURIES プログラム 2024.8

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隠れ難聴について知ろう―検査法の開発と予防－

Role(s)：Informant

九州大学 2024年度九州大学オープンキャンパス 2024.8

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Hidden hearing loss とその評価方法について

Role(s)：Appearance,　Lecturer,　Informant

聴覚補償研究会第5回近畿聴覚補償研究会 2024.7

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講座Ⅱ 「『隠れ難聴』について

Role(s)：Appearance,　Lecturer,　Informant

一般社団法人日本補聴器販売店協会九州・沖縄支部第33回補聴器販売講習会 2023.11

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講座Ⅱ　「『隠れ難聴』について」

一般社団法人日本補聴器販売店協会九州・沖縄支部リモート九州沖縄支部事務局（九州リオン株式会社）会議室 2023.11

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Type：Lecture

オージオグラム上では問題ないが、騒音下において聞き取りが困難になる「隠れ難聴」。
なぜそのような症状が起きるのか？そのメカニズムはどのようなものなのでしょうか？
音声に対する聴性脳幹反応の測定と解析およびその応用

Role(s)：Appearance,　Lecturer,　Informant

日本聴覚医学会 ERA・OAE研究会第10回ERA・OAE研究会 2015.7

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Type：Seminar, workshop

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