記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Clinical Neurophysiology  

Objective: This study aimed to evaluate whether auditory brainstem response (ABR) using a paired-click stimulation paradigm could serve as a tool for detecting cochlear synaptopathy (CS). Methods: The ABRs to single-clicks and paired-clicks with various inter-click intervals (ICIs) and scores for word intelligibility in degraded listening conditions were obtained from 57 adults with normal hearing. The wave I peak amplitude and root mean square values for the post-wave I response within a range delayed from the wave I peak (referred to as the RMSpost-w1) were calculated for the single- and second-click responses. Results: The wave I peak amplitudes did not correlate with age except for the second-click responses at an ICI of 7 ms, and the word intelligibility scores. However, we found that the RMSpost-w1 values for the second-click responses significantly decreased with increasing age. Moreover, the RMSpost-w1 values for the second-click responses at an ICI of 5 ms correlated significantly with the scores for word intelligibility in degraded listening conditions. Conclusions: The magnitude of the post-wave I response for the second-click response could serve as a tool for detecting CS in humans. Significance: Our findings shed new light on the analytical methods of ABR for quantifying CS.

DOI： 10.1016/j.clinph.2024.06.005

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Journal of Cognitive Neuroscience  

Attention to the relevant object and space is the brain's strategy to effectively process the information of interest in complex environments with limited neural resources. Numerous studies have documented how attention is allocated in the visual domain, whereas the nature of attention in the auditory domain has been much less explored. Here, we show that the pupillary light response can serve as a physiological index of auditory attentional shift and can be used to probe the relationship between space-based and object-based attention as well. Experiments demonstrated that the pupillary response corresponds to the luminance condition where the attended auditory object (e.g., spoken sentence) was located, regardless of whether attention was directed by a spatial (left or right) or nonspatial (e.g., the gender of the talker) cue and regardless of whether the sound was presented via headphones or loudspeakers. These effects on the pupillary light response could not be accounted for as a consequence of small (although observable) biases in gaze position drifting. The overall results imply a unified audiovisual representation of spatial attention. Auditory object-based attention contains the space representation of the attended auditory object, even when the object is oriented without explicit spatial guidance.

DOI： 10.1162/jocn_a_01935

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リポジトリ公開URL： https://hdl.handle.net/2324/7178611

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Scientific Reports  

Individuals with autism spectrum disorders (ASD) are reported to exhibit degraded performance in sound localization. This study investigated whether the sensitivity to the interaural level differences (ILDs) and interaural time differences (ITDs), major cues for horizontal sound localization, are affected in ASD. Thresholds for discriminating the ILD and ITD were measured for adults with ASD and age- and IQ-matched controls in a lateralization experiment. Results show that the ASD group exhibited higher ILD and ITD thresholds than the control group. Moreover, there was a significant diversity of ITD sensitivity in the ASD group, and it contained a larger proportion of participants with poor ITD sensitivity than the control group. The current study suggests that deficits in relatively low-level processes in the auditory pathway are implicated in degraded performance of sound localization in individuals with ASD. The results are consistent with the structural abnormalities and great variability in the morphology in the brainstem reported by neuroanatomical studies of ASD.

DOI： 10.1038/s41598-022-23346-y

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リポジトリ公開URL： https://hdl.handle.net/2324/7178608

記述言語：その他   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.cnp.2021.04.004

リポジトリ公開URL： https://hdl.handle.net/2324/7178609

記述言語：その他   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.neulet.2016.11.042

リポジトリ公開URL： https://hdl.handle.net/2324/7178610

開催年月日： 2024年9月 - 2023年4月

記述言語：日本語  

開催地：名古屋工業大   国名：日本国  

リポジトリ公開URL： https://hdl.handle.net/2324/7178602

開催年月日： 2023年10月

記述言語：日本語   会議種別：口頭発表（一般）  

開催地：千葉　幕張メッセ　国際会議場   国名：日本国  

開催年月日： 2015年5月

記述言語：英語  

国名：大韓民国  

開催年月日： 2014年10月

記述言語：英語   会議種別：口頭発表（一般）  

国名：大韓民国  

開催年月日： 2014年5月

記述言語：英語  

国名：オーストラリア連邦  

記述言語：日本語   出版者・発行元：日本音響学会  

CiNii Books

CiNii Research

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記述言語：日本語  

J-GLOBAL

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記述言語：日本語   出版者・発行元：日本音響学会  

CiNii Books

CiNii Research

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記述言語：日本語  

対象： 社会人・一般,　学術団体,　企業,　市民団体,　行政機関

種別：講演会

オージオグラム上では問題ないが、騒音下において聞き取りが困難になる「隠れ難聴」。
なぜそのような症状が起きるのか？そのメカニズムはどのようなものなのでしょうか？