Updated on 2025/04/17

写真a

 
MIYAZAKI YOSHIYUKI
 
Organization
Faculty of Agriculture Associate Professor
Title
Associate Professor
Contact information
メールアドレス
External link

Degree

  • Ph.D. (agriculture)

Research History

  • 平成22年1月1日〜平成23年7月31日 特定非営利活動法人NPOフコイダン研究所 主任研究員 平成23年8月1日〜平成26年9月30日 特定非営利活動法人NPOフコイダン研究所 理事長 平成26年10月1日〜現在 特定非営利活動法人NPOフコイダン研究所 理事   

    平成22年1月1日〜平成23年7月31日 特定非営利活動法人NPOフコイダン研究所 主任研究員 平成23年8月1日〜平成26年9月30日 特定非営利活動法人NPOフコイダン研究所 理事長 平成26年10月1日〜現在 特定非営利活動法人NPOフコイダン研究所 理事

  • 平成15年4月1日〜平成16年4月30日 科学技術振興事業団(PRESTO) 研究員 平成16年5月1日〜平成21年12月31日 佐賀大学 医学部 分子生命科学講座 助教   

Research Interests・Research Keywords

  • Research theme: Studies on immunomodulatory effects of food components Studies on immunomodulatory effects of sulfated polysaccharides Development of novel analytical methods for polysaccharides

    Keyword: polysaccharides functional foods immune regulation food analysis

    Research period: 2016.4 - 2021.3

Papers

  • Profiling sulfate content of polysaccharides in seaweed species using a ligand-assisted 1H-NMR assay Reviewed International journal

    #Juneha Bak, Yoshiyuki Miyazaki, @Hayato Nakano, Toshiro Matsui

    Food Science and Technology Research   27 ( 3 )   505 - 510   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3136/fstr.27.505

  • Ligand-aided 1H Nuclear Magnetic Resonance Spectroscopy for Non-destructive Estimation of Sulfate Content in Sulfated Saccharides Reviewed International journal

    #Juneha BAK, Yoshiyuki MIYAZAKI, @Hayato NAKANO, Toshiro MATSUI

    Analytical Sciences   36 ( 10 )   1269 - 1274   2020.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2116/analsci.20P163

  • The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae Reviewed

    Yoshiyuki Miyazaki, Yuri Iwaihara, Juneha Bak, Hayato Nakano, Shugo Takeuchi, Hideaki Takeuchi, Toshiro Matsui, Daisuke Tachikawa

    Biochemical and Biophysical Research Communications   516 ( 1 )   245 - 250   2019.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    The present study investigated immune stimulatory effects of Cladosiphon okamuranus-derived fucoidan to activate murine macrophage-like cell line RAW264, and the functional relationship with zymosan, a Saccharomyces cerevisiae-derived β-glucan. The production of nitric oxide (NO) and tumor necrosis factor-α (TNF-α) in RAW264 cells were remarkably enhanced in the presence of 10 μg/mL fucoidan, and the stimulatory effects of fucoidan were maximally augmented in combinational treatment with 500 ng/mL zymosan, whereas any TLR ligands had no those effects. Confocal microscopic analyses suggested that fucoidan bound on plasma membrane, and it was estimated that some cell surface molecules acted as receptor for fucoidan because cytochalasin D, an inhibitor of phagocytosis, did not affect the immune enhancing activities, whereas methyl-β-cyclodextrin (MβCD), a general agent for disruption of lipid rafts, diminished that. Furthermore, it was revealed that the additive effects of zymosan on the immune activation with fucoidan was thought to be mediated by dectin-1 based on the results with dectin-1-knockdown RAW264 cells. All of results suggested that fucoidan and some kinds of β-glucan would cooperatively reinforce the activity of innate immune cells via interactive receptor crosstalk.

    DOI: 10.1016/j.bbrc.2019.06.010

  • ザクロ酢のヒスタミン放出抑制活性におけるポリフェノール化合物の関与 Reviewed

    宮﨑 義之, 倉田 有希江, 古賀 裕章, 山口 智, 立花 宏文, 山田 耕路

    日本食品科学工学会   63 ( 2 )   63 - 69   2016.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Histamine release by granulocytes is a critical event in the induction of type I allergy. We investigated the effects of four different fruit vinegars made from yama-budo, haskap, blueberry and pomegranate on histamine release by the basophilic leukemia cell line RBL-2H3. Results clearly indicated that these fruit vinegars, especially pomegranate vinegar, have potent inhibitory effects on histamine release. We then performed adsorption chromatography with Diaion HP20 to estimate the bioactive components in pomegranate vinegar; the fraction eluted by 50% ethanol (EtOH) showed the most potent suppressive effect. Next, we subjected the 50% EtOH-fraction to liquid-liquid division with ethyl acetate (AcOEt), and suppressive activity was observed in both the water and AcOEt layer fractions, indicating the existence of multiple bioactive components. Furthermore, suppression of histamine release by each fraction was almost completely abolished by treatment with polyphenol adsorbent polyvinylpolypyrrolidone. These results suggested that the pomegranate vinegar contains multiple polyphenol compounds involved in the suppression of histamine release by granulocytes.

    DOI: 10.3136/nskkk.63.63

  • ブロッコリーのビタミンC, S-メチルメチオニン, ポリフェノール含有量の部位別解析と細胞機能への影響 Invited Reviewed

    上田 京子, 塚谷 忠之, 村山 加奈子, 倉田 有希江, 竹田 絵里, 大塚 崇文, 高井 美佳, 宮﨑 義之, 立花 宏文, 山田 耕路

    日本食品科学工学会   62 ( 5 )   242 - 249   2015.5

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    We studied the nutritional components and functional activities of 6 parts (flower bud, stem, lower main stalk, leaf stalk, leaf, root) of raw whole broccoli (Brassica oleracea var. Italica). Flower buds showed the highest levels of vitamin C (188.2mg/100g) and S-methylmethionine (16.7mg/100g). The buds contained 64.9mg/100g of polyphenols. Moreover, they exhibited the highest histamine release inhibitory activity. The vitamin C, S-methylmethionine and polyphenol contents of the leaves were 18%, 29% and 3.1 times those of flower buds, respectively. The leaves showed histamine release inhibitory activity and leukotriene release inhibitory activity. Additionally, the leaves tended to decrease IgE production. The leaves also showed anti-allergic activity as compared with flower buds. The vitamin C, S-methylmethionine and polyphenol contents of the roots were 13%, 25% and 83% of those of flower buds, respectively. Notably, aqueous extracts of roots produced the highest proliferative arrest in MCF-7 human breast cancer cells. These results suggest that useful components exist not only in the edible flower buds but in all parts of broccoli.

    DOI: 10.3136/nskkk.62.242

▼display all

Presentations

  • The anti-inflammatic activity of a sulfated polysaccharide Fucoidan in innate immune cells International conference

    Y Miyazaki, T Satoyama, @H Nakano, @S Takeuchi, @H Takeuchi, @D Tachikawa

    106th Annual Meeting of The American Association of Immunologists  2022.5 

     More details

    Event date: 2022.5

    Language:English   Presentation type:Oral presentation (general)  

    Fucoidan is a series of natural sulfated polysaccharides derived from brown seaweeds and have reported to possess various biological activities such as anti-tumor, anti-virus, and immuno-modulatory effects. In previous study, we revealed that fucoidan derived from Cladosiphon okamuranus activated murine macrophage-like cell line RAW264 cooperatively with Zymosan, a Saccharomyces cerevisiae-derived β-glucan. On the other hand, several reports demonstrated that fucoidan inhibited lipopolysaccharide (LPS)-induced production of nitrogen oxide (NO) and inflammatory cytokines by RAW264 cells. Therefore, in this study, we investigated the potential of fucoidan derived from Undaria pinnatifida to regulate the excessive activation of RAW264 cells in response to overstimulation with pathogen components. RAW264 cells were inoculated at 20000 cells/well in 96-well culture plates, and after a recovery culture for 24 hr, the cells were treated with fucoidan with or without appropriate concentrations of each ligand for pattern recognition receptors (PRRs) including Toll-like receptors (TLRs). Whereas the production of NO was significantly enhanced with fucoidan alone, it was dose-dependently inhibited by fucoidan under stimulation with Pam3CSK4 (TLR1/TLR2 ligand), heat killed Listeria monocytogenes (HKLM, TLR2 ligand), LPS (TLR4 ligand), Pam2CGDPKHPKSF (FSL-1, TLR2/TLR6 ligand). These results suggested that fucoidan have beneficial ability to alleviate excessive inflammatory reaction during pathogenic infection and maintain suitable immune balance.

  • in vitro実験系を用いたフコイダンのヒト腸内細菌叢に対する効果の解析

    #大野波月, @中野勇人, @柴崎哲哉, 里山俊哉, 宮﨑義之, 中山二郎

    日本農芸化学会  2022.3 

     More details

    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

  • Anti-angiogenic effect of fucoidan-mix AG via improvement of tumor microenvironment in a mouse melanoma model

    宮﨑義之,#朴俊夏,@中野勇人,@竹内秀吾,@竹内秀晃, @立川大介

    第50回日本免疫学会  2021.12 

     More details

    Event date: 2021.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

    Fucoidan is a series of natural sulfated polysaccharides constitute viscous component of brown seaweeds. Previously, we reported that a mixed preparation consists of high-molecular weight fucoidans derived from Okinawa-mozuku and Mekabu (sporophyll of Wakame) and Agaricus blazei mycelium extract, which named fucoidan-mix AG, acted to reinforce anti-tumor immune functions. In this study, we evaluated dietary effects of fucoidan-mix AG on tumor angiogenesis with C57BL/6 mice subcutaneously implanted basement membrane matrix (GeltrexTM) enclosing 5x104 mitomycin C-treated B16 melanoma cells or 500 ng/mL vascular endothelial growth factor (VEGF), and 2% fucoidan-mix AG containing diet was fed for 7 days before and after the matrix injection. As the result, accumulation of hemoglobin (Hb) and CD31-positive cells in the B16- enclosed matrix was lower by the fucoidan-mix AG feeding, which indicated that fucoidan-mix AG was effective to suppress tumor angiogenesis. In contrast, the Hb contents in the VEGF- enclosed matrix were not affected by the fucoidan-mix AG intake. Because the VEGF gene expression in the B16-enclosed matrix was reduced in the fucoidan-mix AG-fed mice, it was guessed that fucoidan-mix AG did not inhibit angiogenic activity of VEGF but suppressed VEGF production. In this context, the matrix infiltration of CD206-positive macrophages, which known to produce VEGF, were declined in the fucoidan-mix AG-fed mice. Furthermore, fucoidan-mix AG decreased matrix accumulation of Treg, and delayed B16 tumor growth. In conclusion, fucoidan-mix AG was expected to be effective in inhibition of tumor angiogenesis by improving immunosuppressive tumor microenvironment.

  • がん性血管新生および腫瘍の形成に及ぼすフコイダン− アガリクスミックス(CUA-フコイダン)の摂食効果

    宮﨑義之,#朴俊夏,@中野勇人,@竹内秀吾,@竹内秀晃, @立川大介

    第68回日本食品科学工学会  2021.8 

     More details

    Event date: 2021.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

    【目的】 フコイダンは,L-フコースを主な構成糖とする褐藻類由来の天然硫酸 化多糖であり,抗がん作用や抗ウイルス作用などの生理活性が報告されている. 先の研究で我々は, オキナワモズクおよびメカブに由来する2種類のフコイダン とアガリクス菌糸体エキス末を配合したフコイダン-アガリクスミックス(通称: CUA-フコイダン)が,免疫増強作用を通してがん腫瘍形成を効果的に抑制する ことを明らかにしてきた.本研究では,新たな視点としてがん性血管新生に着目 し CUA-フコイダンの摂食効果とその作用機序を検証した.
    【方法】 本試験では C57BL/6 マウス(n=6)を用い,マイトマイシン C 処理により 増殖を阻害した 5x104 個の B16 メラノーマ細胞または 500 ng/mL の血管内皮細 胞増殖因子(VEGF)を封入した基底膜マトリクス(GeltrexTM)をマウスの背部皮 下に注射した.マトリクス皮下注射の前後 7 日間にわたり CUA-フコイダンを 2% 重量添加した AIN-93G 準拠食を自由摂食させ,マトリクスゲル内での血管形成 (ヘモグロビン(Hb)蓄積,血管内皮細胞数)および免疫細胞浸潤を評価した. 【結果】 B16 細胞を封入したマトリクスゲルにおける Hb 蓄積量は,CUA-フコイ ダン摂取群で有意に低値を示し,CD31 陽性血管内皮細胞の割合もまた CUA- フコイダン摂取群で減少傾向が観察された.これらの結果から,CUA-フコイダ ンはがん性血管新生に対して抑制作用を有することが示された.一方,VEGF を封入したマトリクスゲルでの Hb 蓄積には CUA-フコイダン摂取の効果は観察 されず,VEGF の血管新生誘導作用には影響を及ぼさないことが示された.し かし,ゲル中の VEGF 遺伝子発現は CUA-フコイダン摂取群で低値を示してお り,血管新生抑制の作用機序の一つとして,腫瘍内で VEGF を産生する CD206 陽性マクロファージの浸潤が CUA-フコイダン摂取に伴い減少することが考えら れた.さらに,CUA-フコイダンが抗腫瘍免疫の抑制に働く制御性 T 細胞(Treg) の浸潤減少や B16 腫瘍の成長遅延に働く可能性が併せて示された.以上の結 果から,CUA-フコイダンは腫瘍内の免疫抑制的な環境を改善し,がん性血管 新生および腫瘍形成の効果的な阻害に寄与することが期待された.

  • Regulatory mechanism of fucoidan-mix AG in intestinal mucosal immune cells International conference

    Y Miyazaki, #J Bak, @H Nakano, @S Takeuchi, @H Takeuchi, @D Tachikawa

    105th Annual Meeting of The American Association of Immunologists  2021.5 

     More details

    Event date: 2021.5

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Online  

    Fucoidan is a series of natural sulfated polysaccharides contained in brown sea algae, and their beneficial physiological activities such as anti-tumor, anti-virus and immune regulatory effects have been reported. In previous studies, we proved that fucoidans derived from Cladosiphon okamuranus (C. okamuranus) and Undaria pinnatifida effectively improved anti-tumor immunity and tumor vaccine efficiency in combination with an Agaricus blazei mycelium extract. It is thought that the fucoidan-agaricus mix (named fucoidan-mix AG) stimulate innate immune cells to activate intestinal and mucosal immune reaction, but actual target immune tissues and cells by fucoidan have not been evidenced yet. In this study, we investigated action mechanisms of fucoidan in regulation of mucosal immune activities. At first, immune cells were isolated from Payer’s patches, mesenteric lymph node (MLN) and intestinal epithelia of Balb/c mice, then stained with fluorophore-labeled fucoidan. As the results, it was revealed that fucoidan directly interact with lymphocytes besides dendritic cells and macrophages existing in these intestinal immune tissues. Furthermore, immune cells from Payer’s patches and MLN stimulated with fucoidan from C. okamuranus and fucoidan-mix AG produced more TNF-α, IL-12 and Th1 cytokine IFN-γ. The production of an immunosuppressive cytokine IL-10 also was augmented in the fucoidan-treated immune cells, which suggesting that fucoidan balanced immune system to prevent occurrence of excessive reaction. In addition, it was newly proved that fucoidan directly stimulated T lymphocytes to induce enhanced IFN-γ production.

▼display all

MISC

  • 高分子CUAフコイダン摂取による健常人の唾液IgA産生増強

    宮﨑 義之

    Bio Industry   2021.4

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    フコイダンは、褐藻類の”ぬめり”成分を構成する天然硫酸化多糖類である。免疫力の向上や抗ウイルス作用に関する基礎的な研究報告は多いものの、臨床学的な知見は未だ少ない。本稿では、唾液分泌型IgA(sIgA)を口腔内粘膜免疫の指標とする健常人を対象とした高分子フコイダン-アガリクスミックス(以下、CUAフコイダン)投与試験を紹介する。検討の結果、CUAフコイダンが粘膜免疫の増強に寄与する可能性が示され、口腔や上気道等における感染防御およびアレルギー疾患の病態緩和に貢献することが期待される。

  • いちご果実由来乳酸菌 Lactobacillus plantarum AMAOU を用いた食品素材の開発と機能性評価

    宮﨑 義之, 中溝 公次, 柴崎 哲哉

    食品と開発 2019年4月号 特集/食成分による腸内環境活性   2019.4

     More details

    Language:Japanese  

  • フコイダン−アガリクスミックス摂取によるペプチドワクチン処置マウスにおけるがん抗原特異的免疫応答の効率的誘導 Reviewed

    宮﨑 義之

    New Food Industry   2019.2

     More details

    Language:Japanese  

  • 第III編 成分単離・同定, 作用機序解析 第1章 成分単離・同定 4. 多糖類

    宮﨑 義之

    機能性食品開発のための初期評価試験プロトコール集(CMC出版)   2017.6

     More details

    Language:Japanese  

  • 海藻由来機能性多糖フコイダンの免疫増強作用 (特集 水産物由来成分の機能研究)

    宮﨑 義之

    Food style 21   2016.12

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

▼display all

Industrial property rights

Patent   Number of applications: 1   Number of registrations: 0
Utility model   Number of applications: 0   Number of registrations: 0
Design   Number of applications: 0   Number of registrations: 0
Trademark   Number of applications: 0   Number of registrations: 0

Professional Memberships

  • Japan Society for Lactic Acid Bacteria

  • Japan Society for Bioscience, Biotechnology, and Agrichemistry

  • The Japanese Society for Food Science and Technology

  • Japanese Society for Immunology

  • The American Association of Immunologists

▼display all

Committee Memberships

  • 日本食品科学工学会 西日本支部   Councilor   Domestic

    2022.3 - 2024.2   

  • 日本農芸化学会 西日本支部   参与   Domestic

    2020.4 - 2023.12   

Academic Activities

  • 会計

    食品科学工学会第68回大会  ( Japan ) 2021.8

     More details

    Type:Competition, symposium, etc. 

  • 会計

    食品科学工学会第67回大会  ( Japan ) 2020.8

     More details

    Type:Competition, symposium, etc. 

  • Screening of academic papers

    Role(s): Peer review

    2020

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:7

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2019

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:11

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2018

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:4

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

▼display all

Research Projects

  • キャピラリー電気泳動法に基づく天然硫酸化多糖類の品質および機能評価

    Grant number:21K05423  2021 - 2023

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • 農芸化学中小企業産学・産官連携研究

    2020.4 - 2021.3

    日本農芸化学会 

      More details

    Authorship:Collaborating Investigator(s) (not designated on Grant-in-Aid) 

    「あまおう由来乳酸菌と沖縄もずくフコイダンの腸内フローラ改善効果」の検証
    マウス摂食試験により、あまおう乳酸菌およびオキナワモズクフコイダン摂取が腸内細菌叢および腸管免疫に与える影響を検討

  • DOSY-NMR法による硫酸化多糖分析と腸管免疫制御機構に関する 研究

    Grant number:17K07819  2017 - 2019

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

Educational Activities

  • 特別開講科目(後期)の開講
    大学院学生の研究指導

Class subject

  • 食品免疫機能分析学特論

    2022.10 - 2022.12   Fall quarter

  • 食品免疫機能分析学特論

    2021.10 - 2021.12   Fall quarter

  • 機能性多糖分析学特論

    2020.10 - 2020.12   Fall quarter

  • 機能性多糖分析学特論

    2019.10 - 2019.12   Fall quarter

  • 機能性多糖分析学特論

    2018.10 - 2018.12   Fall quarter

▼display all

FD Participation

  • 2021.11   Role:Participation   Title:農学研究院FD「人を対象とする生命科学・医学系研究に関する倫理指針」について

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2021.7   Role:Participation   Title:農学研究院FD「科研費を獲りにいこう! 科研費獲得の技術と工夫」

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2020.9   Role:Participation   Title:科研費を獲りにいこう! 勝ち抜く気合と技術

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2019.6   Role:Participation   Title:令和元年度 第1回農学研究院FD 「優良な博士人材の獲得と育成に向けて ~農学研究院教授に学ぶ ~」

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2016.8   Role:Participation   Title:平成28年度安全衛生セミナー I(リスクアセスメントの導入について)

    Organizer:[Undergraduate school/graduate school/graduate faculty]

▼display all

Social Activities

  • 第2回市民講座  「健康寿命を延ばすための食生活」

    九州大学大学院農学研究院食品免疫機能分析学寄附講座  R4/6/1  九州大学 西新プラザ  2022.6

     More details

    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

    第1部:「健康を維持するためのサプリメントの上手な利用法」 食品免疫機能分析学寄附講座 准教授 宮﨑義之
    第2部:「農産物の有する機能性と味 ~苦味を制する者は健康を制する?~」  高知大学 理事・副学長 受田浩之氏

  • 第1回市民講座  「野菜で健康に!」

    九州大学大学院農学研究院食品免疫機能分析学寄附講座  R3/12/14 九州大学 西新プラザ  2021.12

     More details

    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

    第1部「食べると免疫力アップにつながる海の野菜(海藻)のお話」 九州大学農学研究院 准教授 宮﨑義之
    第2部「Dr.ベジフルの健康になるための野菜の力」髙上青果有限会社 代表取締役 髙上実氏

  • 「海藻多糖類の機能性 〜免疫賦活作用と抗ウイルス作用〜」  第31回食品産業創造展 西日本機能性食品開発研究会セミナー   主催:日刊工業新聞社 企画主催:日本食品科学工学会西日本支部 西日本機能性食品開発研究会   R3/5/19 マリンメッセ福岡(福岡)

    2021

     More details

    「海藻多糖類の機能性 〜免疫賦活作用と抗ウイルス作用〜」  第31回食品産業創造展 西日本機能性食品開発研究会セミナー   主催:日刊工業新聞社 企画主催:日本食品科学工学会西日本支部 西日本機能性食品開発研究会   R3/5/19 マリンメッセ福岡(福岡)

  • 食品保健指導士会 2020年度支部事業計画第1回受託セミナー 「コロナ対策 ̶ 免疫力UPの成分! フコイダンを中心に!」

    公益財団法人日本健康・栄養食品協会  オンライン講演  2020.11

     More details

    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 第49期食品保健指導士養成講習会 「免疫と健康食品の活用」

    公益財団法人日本健康・栄養食品協会  R/1/7/28 パピヨン24(福岡)  2019.7

     More details

    Audience:General, Scientific, Company, Civic organization, Governmental agency

    Type:Other

▼display all

Media Coverage

  • もずくの効能を腸管免疫と腸内環境の改善の観点から健康効果を紹介 Newspaper, magazine

    マキノ出版 月刊誌『ゆほびか』  2021.5

     More details

    もずくの効能を腸管免疫と腸内環境の改善の観点から健康効果を紹介

  • 「FUCOIDAN: Anti-Cancer Functions + Inhibitor of Covid-19?」

    Journal of Modern Healing  2021.3

     More details

    「FUCOIDAN: Anti-Cancer Functions + Inhibitor of Covid-19?」

  • 九州大学におけるオキナワモズク由来フコイダンの機能性研究紹介 Newspaper, magazine

    日刊みなと新聞  2020.4

     More details

    九州大学におけるオキナワモズク由来フコイダンの機能性研究紹介

  • メディカルフロンティア「Japanese Super Foods ニッポン長寿食の秘密」 TV or radio program

    NHK BSプレミアム  2017.11

     More details

    メディカルフロンティア「Japanese Super Foods ニッポン長寿食の秘密」

  • メディカルフロンティア「Japanese Super Foods ニッポン長寿食の秘密」 TV or radio program

    NHK総合沖縄地域放送  2017.11

     More details

    メディカルフロンティア「Japanese Super Foods ニッポン長寿食の秘密」

▼display all