Updated on 2024/07/28

Information

 

写真a

 
SHIMIZU KUNIYOSHI
 
Organization
Faculty of Agriculture Department of Agro-environmental Sciences Associate Professor
School of Agriculture Department of Bioresource and Bioenvironment(Joint Appointment)
Graduate School of Bioresource and Bioenvironmental Sciences Department of Agro-environmental Sciences(Joint Appointment)
Title
Associate Professor
Contact information
メールアドレス
Tel
0926423002
Profile
The investigation of LOHAS-oriented biological activity of forest products and their applications Forest has been known to have healing power for mind and body. Our group deals with LOHAS (Life Of Health And Sustainability) oriented biological aspects of forest products and their mode of action. In most cases this involves investigating the biological activity of extractives of mushroom , woods and plant etc, such as anti-androgenic activity, prevention effect of bone loss in calcium deficient ovariectomized rats of mushroom, healing aroma, and melanin biosynthesis inhibitory activity of wood extractives. Our research cover several practical fields such as cosmetics, aroma, functional food, living environment, toiletry etc. 1, Search for biologically active substance from plants. 2, Search for biologically active substance from mushrooms. 3, Studies on the mode of action of bioactive natural substances and their structural criteria. 4, The physiological and psychological effect of aroma (natural volatiles) on human. 5, Development of bioactive substances and extracts for practical use (cosmetics, aroma, functional food, toiletry and living environment.)
Homepage
External link

Degree

  • PhD

Research History

  • 九州大学ベンチャービジネスラボラトリー:2001年4月〜2002年2月

Research Interests・Research Keywords

  • Research theme:Functional evaluation of honey and isolation and identification of compounds

    Keyword:Honey Isolation and identification Functional evaluation

    Research period: 2020.10

  • Research theme:Establishment of functional evaluation and analysis methods for argan saponins

    Keyword:Argan Argan oil Argan saponins

    Research period: 2020.6

  • Research theme:Evaluation of the functional of Angelica keiskei

    Keyword:Angelica keiskei Evaluation of the functional

    Research period: 2019.10

  • Research theme:Verification of effects on human cognitive function using foods containing peanut extract

    Keyword:Arachis hypogaea

    Research period: 2019.9 - 2020.3

  • Research theme:In vitro functional evaluation test of ethanol and water extract of Houttuynia cordata

    Keyword:Houttuynia cordata

    Research period: 2019.9 - 2020.2

  • Research theme:A supplement containing Nejimebiwa tea as a functionally labeled food that contributes to the suppression of allergic symptoms

    Keyword:Eriobotrya japonica

    Research period: 2019.7 - 2020.2

  • Research theme:Basic research on improvement of cognitive function of ingredients containing Yamabushitake

    Keyword:Hericium erinaceus

    Research period: 2019.4 - 2020.3

  • Research theme:Volatile compounds emitted from Juncus effusus and their functions

    Keyword:Juncus effusus, Igusa,GC/MS,Tatami

    Research period: 2018.4 - 2021.3

  • Research theme:Isolation and Identification of Compounds in AKAJISO(Perilla frutescens var. crispa f. purpurea) and Functional evaluation

    Keyword:AKAJISO(Perilla frutescens var. crispa f. purpurea) Isolation and Identification Functional evaluation

    Research period: 2018.4

  • Research theme:Comparison of the physiological and psychological response of the component profile and human essential oil aroma prepared from cedar leaves and wood parts

    Keyword:Cryptomeria japonica essential oil

    Research period: 2013.4 - 2015.2

  • Research theme:Functional components isolated from Olive

    Keyword:Olive

    Research period: 2013.4

  • Research theme:Search for bioactive compound from the waste of Ejyptian plants

    Keyword:Medicinal Plants from Ejypt

    Research period: 2013.4

  • Research theme:Comparative Biological Study of Roots, Stems, Leaves, and Seeds of Angelica shikokiana Makino

    Keyword:Angelica shikokiana

    Research period: 2013.4

  • Research theme:Wild Mushroom in Nepal: Some potential Candidates as Antioxidant and ACE Inhibition Sources

    Keyword:Wild Mushroom in Nepal

    Research period: 2013.4

  • Research theme:HMGCoA reductase inhibitors from natural resources

    Keyword:HMGCoA reductase inhibitor

    Research period: 2008.5 - 2010.3

  • Research theme:Search for hair growth agents from natural products

    Keyword:hair growth

    Research period: 2008.5 - 2010.3

  • Research theme:Functional components isolated from Eriobotrya japonica

    Keyword:Eriobotrya japonica

    Research period: 2008.5

  • Research theme:Search for bioactive compounds from the bamboo and the skin of bamboo shoot

    Keyword:bamboo shoot, biological activity

    Research period: 2007.5

  • Research theme:Volatile compounds emitted from woods and their functions

    Keyword:terpene, volatile

    Research period: 2006.4

  • Research theme:The physiological and psychological effects of volatiles emitted from natural resources on human

    Keyword:natural product, volatile, aroma, essential oil

    Research period: 2005.4

  • Research theme:The aldose reductase inhibitors from Ganoderma lucidum

    Keyword:aldose reductase, Ganoderma lucidum

    Research period: 2004.4

  • Research theme:国産樹木抽出物からのメラニン生成抑制成分

    Keyword:メラニン、美白成分、Sapium sebiferum、ナンキンハゼ

    Research period: 2003.4

  • Research theme:インドネシア産植物からの生理活性成分の探索

    Keyword:Indonesia, biological activity, plant extract

    Research period: 2003.4

  • Research theme:シイタケ抽出物のメラニン生成抑制効果

    Keyword:Lentinula edodes、シイタケ、メラニン

    Research period: 2003.1

  • Research theme:Search for the compound with estrogenic activity from mushrooms

    Keyword:fruiting body, estrogenic activity, Pleurotus eryngii, Ganoderma lucidum

    Research period: 2002.4

  • Research theme:Search for the preventive compounds from mushroom on benign prostate hyperplasia

    Keyword:Ganoderma lucidum, fruiting body, antiandrogen, 5a-reductase

    Research period: 2001.4

Awards

  • 日本木材学会賞

    2014.2   日本木材学会   霊芝の生理活性の探索ならびに活性発現機構に関する研究

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    第54回 日本木材学会学会賞「霊芝の生理活性の探索ならびに活性発現機構に関する研究」
    森林バイオマスを構成する重要な遺伝子資源、キノコの一種である霊芝(マンネンタケ、Ganoderma lingzhi)の機能性の探索ならびに、その活性発現機構の研究に対する受賞。前立腺肥大症改善効果につながる5α-リダクターゼ阻害活性、男性ホルモン受容体結合活性などの試験管レベルでの実験からスタートし、動物実験、臨床実験まで幅広く、包括的な科学的知見の蓄積に成功。また、骨粗しょう症への効果が期待できるエストロゲン様活性、破骨細胞分化抑制活性、骨密度低下抑制活性等の新規機能性を発見。さらに、糖尿病や糖尿病合併症への有効性が期待されるα-グルコシダーゼ阻害活性、アルドースレダクターゼ阻害活性についても見出し、活性成分を解明し、論文はネイチャーサイエンスに掲載された。加えて、古くからガンに効くキノコとして知られている霊芝の科学的根拠を示す新たなメカニズムとして、チューブリン脱重合活性を有していることも発見した。これら一連の研究に対する受賞である。

  • NH創造性開発賞

    2010.3   九州大学農学研究院   「組成物および飲食品」

  • 日本木材学会奨励賞

    2006.2   日本木材学会   「森林生物資源からの生理活性成分の探索」

  • 黎明研究者賞

    1999.11   日本木材学会九州支部  

Papers

  • Identification of telomere-related genes associated with aging-related molecular clusters and the construction of a diagnostic model in Alzheimer's disease based on a bioinformatic analysis Reviewed International journal

    #Ruan Y., @Lv W., Li S., @Cheng Y., @Wang D., @Zhang C., @Shimizu K.

    Computers in Biology and Medicine   159   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.compbiomed.2023.106922

  • Cytotoxicity evaluation of phytochemicals from stingless bee (Tetragonula biroi) propolis Reviewed International journal

    Toxicon   ( 237 )   2024.1

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Mogroside IIE, an in vivo metabolite of sweet agent, alleviates acute lung injury via Pla2g2a-EGFR inhibition Reviewed International journal

    Food Science and Human Wellness   13 ( 1 )   299 - 312   2024.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.26599/FSHW.2022.9250026

  • Effects of volatile sesquiterpenes from Japanese cedarwood on visual processing in the human brain: an event-related potential study Reviewed International journal

    @Nakashima T., @Sun M., #Honden A., @Yoshimura Y., @Nakagawa T., @Ishikawa H., @Nagano J., @Yamada Y., @Okamoto T., @Watanabe Y., @Yasunari S., @Ohnuki K., @Fujimoto N., @Shimizu K.

    Journal of Wood Science   69 ( 1 )   2023.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s10086-023-02083-4

  • Identification and immunological characterization of PLA2G2A and cell death-associated molecular clusters in idiopathic pulmonary fibrosis Reviewed International journal

    @Lv W., @Mao H., #Ruan Y., @Li S., @Shimizu K., @Zhang L., @Zhang C.

    Life Sciences   331   2023.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.lfs.2023.122071

  • Studies on the Nonalkaloidal Secondary Metabolites of Hippeastrum vittatum (L’Her.) Herb. Bulbs Reviewed International journal

    8 ( 30 )   26749 - 26761   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsomega.2c07886

  • The application of biosurfactant-producing bacteria immobilized in PVA/SA/bentonite bio-composite for hydrocarbon-contaminated soil bioremediation Reviewed International journal

    @Purnomo A.S., @Putra S.R., @Putro H.S., @Hamzah A., @Rohma N.A., @Rohmah A.A., @Rizqi H.D., @Asranudin N., @Tangahu B.V., @Warmadewanthi I.D.A.A., @Shimizu K.

    RSC Advances   13 ( 31 )   21163 - 21170   2023.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d3ra02249h

  • Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound Reviewed International journal

    @Tamrakar S., @Wang D., #Hiraki E., @Han C., #Ruan Y., @Allam A.E., @Amen Y., @Katakura Y., @Shimizu K.

    Molecules   28 ( 11 )   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/molecules28114549

  • Effect of Oral Intake of Flammulina velutipes (Enokitake) on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind, Placebo-Controlled Study on Mental and Physical Health Reviewed International journal

    @Nagae M., @Isa A., @Ishikawa S., @Muta S., @Shimizu K.

    Cosmetics   10 ( 2 )   2023.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/cosmetics10020057

  • Oligomeric Proanthocyanidin Complex from Avocado Seed as A Promising α -glucosidase Inhibitor: Characteristics and Mechanisms Reviewed International journal

    89 ( 3 )   316 - 323   2023.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/a-1878-3916

  • Screening of Asian Natural Materials to Promote β-Endorphin Synthesis Reviewed International journal

    18 ( 2 )   2023.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/1934578X231152964

  • Investigation of pulmonary toxicity evaluation on mice exposed to polystyrene nanoplastics: The potential protective role of the antioxidant N-acetylcysteine Reviewed International journal

    @Wu, Y., @Yao, Y., @Bai, H., @Shimizu, K., @Li, R., & @Zhang, C.

    Science of the Total Environment   855   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.scitotenv.2022.158851

  • Miniaturized ternary deep eutectic solvent-based matrix solid-phase dispersion: A green sample preparation method for the determination of chlorophenols in river sediment Reviewed International journal

    #El-Deen A.K., @Shimizu K.

    Journal of Separation Science   46 ( 2 )   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: DOI: 10.1002/jssc.202200717

  • Natural hydrophobic deep eutectic solvent for vortex-assisted dispersive liquid–liquid microextraction of anti-prostate cancer triple therapy from water and human plasma Reviewed International journal

    184   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.microc.2022.108124

  • Antioxidant, anti-inflammatory and anti-acne activities of stingless bee (Tetragonula biroi) propolis Invited Reviewed International journal

    @Arung E.T., @Syafrizal, @Kusuma I.W., @Paramita S., @Amen Y., @Kim Y.-U., @Naibaho N.M., @Ramadhan R., @Ariyanta H.A., @Fatriasari W., @Shimizu K.

    Fitoterapia   164   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.fitote.2022.105375

  • Melanin Synthesis Inhibition Activity of Compounds Isolated from Bamboo Shoot Skin (Phyllostachys pubescens) Reviewed International journal

    @Ashour A., @Elbermawi A., @Amen Y., @Allam A.E., @Ikeda H., @Nagata M., @Kumagae K., @Azuma T., @Taguchi A., @Takemoto T., @Matsumoto M., @Shimizu K.

    Molecules   28 ( 1 )   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/molecules28010023

  • New benzaldehyde derivatives from the fruiting bodies of Hericium erinaceus with cytotoxic activity Reviewed International journal

    #Ruan Y., @Han C., @Wang D., @Inoue Y., @Amen Y., @Othman A., @Mittraphab Y., @Nagata M., @Shimizu K.

    Natural Product Research   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14786419.2023.2169687

  • Phytochemical, ethnomedicinal uses and pharmacological profile of Juncus decipiens (Buchenau) Nakai (common rush) Reviewed International journal

    #Ullah S., @Amen Y., @Shimizu K.

    Natural Product Research   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14786419.2023.2223749

  • Soil pH and divalent cations after clear-cutting on a Japanese cypress plantation Invited Reviewed International journal

    Journal of Forest Research   2022.12

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  • Phytochemical Analysis, Anti-inflammatory, and Anticancer Activities of the Halophyte Herb Bassia indica Reviewed International journal

    #Othman A., @Amen Y., @Inoue Y., @Shimizu K.

    Natural Product Communications   17 ( 11 )   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/1934578X221137412

  • New Butyroside D from Argan Press Cake Possess Anti-Melanogenesis Effect via MITF Downregulation in B16F10 and HEM Cells Reviewed International journal

    @Bouhoute M., @Amen Y., @Bejaoui M., @Mizushima A.K.O., @Shimizu K., @Isoda H.

    International Journal of Molecular Sciences   23 ( 24 )   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms232416021

  • Suppressive Effect of Fruiting Bodies of Medicinal Mushrooms on Demyelination and Motor Dysfunction in a Cuprizone-Induced Multiple Sclerosis Mouse Model Reviewed International journal

    @Yamashina K., @Yamamoto S., @Matsumoto M., @Iwasa K., @Takeda N., @Haruta C., @Maruyama K., @Shimizu K., @Yoshikawa K.

    International Journal of Medicinal Mushrooms   24 ( 9 )   15 - 24   2022.12

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  • Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community Reviewed International journal

    Akane Mihara, @Tomoyuki Ohara, @Jun Hata, Sanmei Chen, @Takanori Honda, Sonam Tamrakar, @Akiko Isa, @Dongmei Wang, @Kuniyoshi Shimizu, @Yoshinori Katakura, Koji Yonemoto, @Tomohiro Nakao, @Takanari Kitazono, @Toshiharu Ninomiya

    Scientific reports   12 ( 1 )   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Anti-proliferative and Apoptotic Activity Against an Acute Myeloid Leukemia Cell Line by Constituents from Ficus benghalensis Reviewed International journal

    Heba Ali Hassan, Ahmed E. Allam, Rania Alaaeldin, Muhamad Mustafa, Reham H. Mohyeldin, @Kuniyoshi Shimizu, Sayed F. Abdelwahab, Samar Y. Desouky, Khaled M. Mohamed, Mohamed S. Kamel

    Revista Brasileira de Farmacognosia   2022.11

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  • A Comprehensive In Silico Study of New Metabolites from Heteroxenia fuscescens with SARS-CoV-2 Inhibitory Activity Invited Reviewed International journal

    @Abdelkarem F.M., @Nafady A.M., @Allam A.E., @Mostafa M.A.H., @Al Haidari R.A., @Hassan H.A., @Zaki M.E.A., @Assaf H.K., @Kamel M.R., @Zidan S.A.H., @Sayed A.M., @Shimizu K.

    Molecules   27 ( 21 )   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/molecules27217369

  • Undescribed glucosylceramide, flavonol triglycoside, and oleanane saponin from the halophyte agathophora alopecuroides: Promising candidates for stimulating ceramide synthesis Reviewed International journal

    #Othman, A., @Amen, Y., @Nagata, M., & @Shimizu, K.

    Phytochemistry   202   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi:10.1016/j.phytochem.2022.113320

  • A new cycloartane triterpene and other phytoconstituents from the aerial parts of Euphorbia dendroidesv Reviewed International journal

    @Ahmed R. Hassan, Ahmed Ashour, Yhiya Amen, @Maki Nagata, Sayed A. El-Toumy, @Kuniyoshi Shimizu

    Natural Product Research   36 ( 3 )   2022.11

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  • Utilization of hydrophilic and hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of bicalutamide from water and spiked human plasma Reviewed International journal

    @El-Deen, A. K., @Elmansi, H., & @Shimizu, K.

    Sustainable Chemistry and Pharmacy   29   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.scp.2022.100825

  • Lycium schweinfurthii: new secondary metabolites and their cytotoxic activities Reviewed International journal

    #Elbermawi A., @Halim A.F., @Mansour E.-S.S., @Ahmad K.F., @Elsbaey M., @Ashour A., @Amen Y., @El-Gamil M.M., @Tomofumi M., @Shimizu K.

    Natural Product Research   36 ( 20 )   5134 - 5141   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14786419.2021.1922902

  • Potential of Hibiscus sabdariffa L. and Hibiscus Acid to Reverse Skin Aging Reviewed International journal

    #Wang, D., @Nagata, M., @Matsumoto, M., @Amen, Y., @Wang, D., & @Shimizu, K.

    Molecules   27 ( 18 )   2022.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/molecules27186076

  • Anti-Obesity Evaluation of Averrhoa carambola L. Leaves and Assessment of Its Polyphenols as Potential α-Glucosidase Inhibitors Reviewed International journal

    27 ( 16 )   2022.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Possible neuroprotective effects of amide alkaloids from Bassia indica and Agathophora alopecuroides: in vitro and in silico investigations Reviewed International journal

    #Ahmed Othman, #Ahmed M. Sayed, Yhiya Amen, @Kuniyoshi Shimizu

    RSC Advances   12 ( 29 )   18746 - 18758   2022.7

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  • Stress amelioration and anti-inflammatory potential of Shiikuwasha (Citrus depressa Hayata) essential oil, limonene, and γ-terpinene Reviewed International journal

    147   467 - 471   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.sajb.2022.01.028

  • Validation of the potential anti-inflammatory activity of Plumbago auriculata Lam Reviewed International journal

    @Sherif, A. E., @Amen, Y., & @Shimizu, K.

    South African Journal of Botany   147   467 - 471   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.sajb.2022.01.028

  • Fabrication of graphitic carbon nitride/ZnTi-mixed metal oxide heterostructure: Robust photocatalytic decomposition of ciprofloxacin Reviewed International journal

    Chitiphon Chuaicham, Karthikeyan Sekar, Vellaichamy Balakumar, @Yanisa Mittraphab,@ Kuniyoshi Shimizu, Bunsho Ohtani, @Keiko Sasaki

    Journal of Alloys and Compounds   906   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Correction to: Evaluation of medicinal plants from Central Kalimantan for antimelanogenesis (Journal of Natural Medicines Reviewed International journal

    Enos Tangke Arung, Irawan Wijaya Kusuma, Eva Oktoberyani Christy, @Kuniyoshi Shimizu, Ryuichiro Kondo

    Journal of Natural Medicines   76 ( 3 )   2022.6

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  • Conducting the RBD of SARS-CoV-2 Omicron Variant with Phytoconstituents from Euphorbia dendroides to Repudiate the Binding of Spike Glycoprotein Using Computational Molecular Search and Simulation Approach Reviewed International journal

    Heba Ali Hassan, Ahmed R. Hassan, Eslam A.R. Mohamed, Ahmad Al-Khdhairawi, Alaa Karkashan, Roba Attar, Khaled S. Allemailem, Waleed Al Abdulmonem, @Kuniyoshi Shimizu, Iman A.M. Abdel-Rahman, Ahmed E. Allam

    Molecules   27 ( 9 )   2022.5

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  • Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation Invited Reviewed International journal

    Wen Shi, Jiatong Hao, Yanliang Wu, Chang Liu, @Kuniyoshi Shimizu, Renshi Li, Chaofeng Zhang

    European Journal of Pharmacology   921   2022.4

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  • Suspect and non-target screening workflow for studying the occurrence, fate, and environmental risk of contaminants in wastewater using data-independent acquisition Reviewed International journal

    #l-Deen, Asmaa Kamal, @Shimizu, Kuniyoshi

    Journal of chromatography A   1667   2022.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.chroma.2022.462905

  • Antioxidant and Protective Effect of Acetone Extract of Entada phaseoloides Leaves on UVB-Irradiated Human Epidermal Keratinocytes (HaCaT cells) by Inhibiting COX-2, iNOS, and Caspase-3 Activation Reviewed International journal

    @Yanisa Mittraphab, @Maki Nagata, @Masako Matsumoto, @Kuniyoshi Shimizu

    Natural product communications   17 ( 3 )   2022.3

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  • Effects of oral administration of equine placental extract supplement on the facial skin of healthy adult women: A randomized, double-blind, placebo-controlled study Reviewed International journal

    @Masumi Nagae, Tomoe Nishio, Koichiro Ohnuki, @Kuniyoshi Shimizu

    Health Science Reports   5 ( 2 )   2022.3

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  • Suppressive Effect of Fruiting Bodies of Medicinal Mushrooms on Demyelination and Motor Dysfunction in a Cuprizone-Induced Multiple Sclerosis Mouse Model Reviewed International journal

    :Kota Yamashina, Shinji Yamamoto, @Masako Matsumoto, Kensuke Iwasa, Nonoka Takeda, Chikara Haruta, Kei Maruyama, @Kuniyoshi Shimizu, Keisuke Yoshikawa

    International Journal of Medicinal Mushrooms   24 ( 9 )   15 - 24   2022.3

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  • Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans Reviewed International journal

    Minkai Sun, @Taisuke Nakashima, Yuri Yoshimura, Akiyoshi Honden, Toshinori Nakagawa, Yu Nakashima, Makoto Kawaguchi, Yukimitsu Takamori, Yoshitaka Koshi, Rimpei Sawada, Shinsuke Nishida, Koichiro Ohnuki, @Kuniyoshi Shimizu

    International journal of environmental research and public health   19 ( 3 )   2022.2

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  • Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice Reviewed International journal

    Renshi Li, Ce Chen, Bei Liu, Wen Shi, @Kuniyoshi Shimizu, Chaofeng Zhang

    Phytomedicine   94   2022.1

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  • Anti-Phototoxicity Effect of Phenolic Compounds from Acetone Extract of Entada phaseoloides Leaves via Activation of COX-2 and iNOS in Human Epidermal Keratinocytes Reviewed International journal

    @Yanisa Mittraphab, Yhiya Amen, @Maki Nagata, @Masako Matsumoto, @Dongmei Wang, @Kuniyoshi Shimizu

    Molecules   27 ( 2 )   2022.1

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  • Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features Reviewed International journal

    @Amen, Y., @Elsbaey, M., #Othman, A., @Sallam, M., & @Shimizu, K.

    Molecules   26 ( 24 )   2021.12

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    DOI: 10.3390/molecules26247646

  • Single-step synthesis of oxygen-doped hollow porous graphitic carbon nitride for photocatalytic ciprofloxacin decomposition Reviewed International journal

    #Chuaicham C., #Sekar K., @Xiong Y., @Balakumar V., @Mittraphab Y., @Shimizu K., @Ohtani B., @Dabo I., @Sasaki K.

    Chemical Engineering Journal   425   2021.12

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    DOI: 10.1016/j.cej.2021.130502

  • Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines Reviewed International journal

    @Arung E.T., @Ramadhan R., @Khairunnisa B., @Amen Y., @Matsumoto M., @Nagata M., @Kusuma I.W., @Paramita S., @Sukemi, @Yadi, @Tandirogang N., @Takemoto N., @Syafrizal, @Kim Y.-U., @Shimizu K.

    Saudi Journal of Biological Sciences   28 ( 12 )   7182 - 7189   2021.12

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    DOI: 10.1016/j.sjbs.2021.08.017

  • Deep eutectic solvents as promising green solvents in dispersive liquid–liquid microextraction based on solidification of floating organic droplet: Recent applications, challenges and future perspectives Reviewed International journal

    26 ( 23 )   2021.12

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    DOI: doi:10.3390/molecules26237406

  • In silico study of natural compounds from sesame against COVID-19 by targeting Mpro, PLpro and RdRp Reviewed International journal

    @Allam A.E., @Amen Y., @Ashour A., @Assaf H.K., @Hassan H.A., @Abdel-Rahman I.M., @Sayed A.M., @Shimizu K.

    RSC Advances   11 ( 36 )   22398 - 22408   2021.11

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    DOI: 10.1039/d1ra03937g

  • Chemical constituents from Limonium tubiflorum and their in silico evaluation as potential antiviral agents against SARS-CoV-2 Reviewed International journal

    @Hassan A.R., @Sanad I.M., @Allam A.E., @Abouelela M.E., @Sayed A.M., @Emam S.S., @El-Kousy S.M., @Shimizu K.

    RSC Advances   11 ( 51 )   32346 - 32357   2021.9

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    DOI: 10.1039/d1ra05927k

  • A novel acylated flavonol tetraglycoside and rare oleanane saponins with a unique acetal-linked dicarboxylic acid substituent from the xero-halophyte Bassia indica Reviewed International journal

    #Ahmed Othman, @Yhiya Amen, @Kuniyoshi Shimizu

    Fitoterapia   152   2021.6

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    DOI: 10.1016/j.fitote.2021.104907

  • Synthesis of new selective cytotoxic ricinine analogues against oral squamous cell carcinoma Reviewed International journal

    #El-Naggar M.H., #Abdel Bar F.M., #Harsha C., #Monisha J., #Shimizu K., #Kunnumakkara A.B., #Badria F.A.

    Natural Product Research   35 ( 13 )   2145 - 2156   2021.6

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    DOI: 10.1080/14786419.2019.1663513

  • Isolation and characterization of novel acetylcholinesterase inhibitors from: Ficus benghalensis L. leaves Reviewed International journal

    Heba Ali Hassan, Ahmed E. Allam, Dalia H. Abu-Baih, Mamdouh F.A. Mohamed, Usama Ramadan Abdelmohsen, @Kuniyoshi Shimizu, Samar Y. Desoukey, Alaa M. Hayallah, Mahmoud A. Elrehany, Khaled M. Mohamed, Mohamed S. Kamel

    RSC Advances   10 ( 60 )   36920 - 36929   2021.6

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    DOI: 10.1039/d0ra06565j

  • A new glucoside with a potent α-glucosidase inhibitory activity from Lycium schweinfurthii Reviewed International journal

    35 ( 6 )   976 - 983   2021.5

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    DOI: 10.1080/14786419.2019.1616730

  • Ent-trachylobane-3β-hydroperoxide, a new diterpene from the root bark of chrozophora oblongifolia (fam.; euphorbiaceae) Reviewed International journal

    35 ( 19 )   3177 - 3184   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14786419.2019.1687477

  • Analysis of Antioxidant and Antiallergic Active Components Extracted From the Edible Insect Oxya yezoensis Reviewed International journal

    #Saiki, M., @Takemoto, N., @Nagata, M., @Matsumoto, M., @Amen, Y., @Wang, D., & @Shimizu, K.

    Natural Product Communications   16 ( 5 )   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/1934578X211023363

  • Pentacylic triterpenes from Lavandula coronopifolia: structure related inhibitory activity on α-glucosidase Reviewed International journal

    35 ( 9 )   1436 - 1444   2021.5

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    DOI: 10.1080/14786419.2019.1655017

  • Modified μ-QuEChERS coupled to diethyl carbonate-based liquid microextraction for PAHs determination in coffee, tea, and water prior to GC–MS analysis: An insight to reducing the impact of caffeine on the GC–MS measurement Reviewed International journal

    #Asmaa Kamal El-Deen, @Kuniyoshi Shimizu

    1171   2021.5

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    DOI: 10.1016/j.jchromb.2021.122555

  • Agronomic characteristics of 30 promising lines of aromatic, red, and black rice and their antioxidant and cytotoxic effects in some cancer cells Reviewed International journal

    Limbongan Y, Ramadhan R, @Shimizu K, Arung ET.

    Biodiversitas   22 ( 4 )   1695 - 1700   2021.4

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    DOI: 10.13057/biodiv/d220412

  • Natural product mogrol attenuates bleomycin-induced pulmonary fibrosis development through promoting AMPK activation Reviewed International journal

    Bei Liu, Jinyu Yang, Jiatong Hao, Haifeng Xie, @Kuniyoshi Shimizu, Renshi Li, Chaofeng Zhang

    Journal of Functional Foods   77   2021.2

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    DOI: 10.1016/j.jff.2020.104280

  • Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight. Invited Reviewed International journal

    #Othman A, @Amen Y, @Matsumoto M, @Nagata M & @Shimizu K

    Natural Product Research   2021.1

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    DOI: 10.1080/14786419.2021.1872572

  • Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation Reviewed International journal

    Han Liang, Rui Cheng, Jiaoyang Wang, Haifeng Xie, Renshi Li, @Kuniyoshi Shimizu, Chaofeng Zhang

    Phytomedicine   81   2021.1

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    DOI: 10.1016/j.phymed.2020.153427

  • Two new polyhydroxylated steroids from Egyptian soft coral Heteroxenia fuscescens (Fam.; Xeniidae) Reviewed International journal

    Fahd M. Abdelkarem, Ezz Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Ahmed Ashour, Gamal A. Mohamed, @Tomofumi Miyamoto, @Kuniyoshi Shimizu

    Natural Product Research   35 ( 2 )   236 - 243   2021.1

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    DOI: 10.1080/14786419.2019.1624958

  • Diadema setosum: isolation of bioactive secondary metabolites with cytotoxic activity toward human cervical cancer Invited Reviewed International journal

    Fahd M. Abdelkarem, Ezz Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Ahmed Ashour, @Kuniyoshi Shimizu

    Natural Product Research   2020.12

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    DOI: 10.1080/14786419.2020.1855162

  • Ursolic acid treatment suppresses cuprizone-induced demyelination and motor dysfunction via upregulation of IGF-1 Invited Reviewed International journal

    Shinji Yamamoto, Chiaki Sakemoto, Kensuke Iwasa, Kei Maruyama, @Kuniyoshi Shimizu, Keisuke Yoshikawa

    Journal of Pharmacological Sciences   144 ( 3 )   119 - 122   2020.11

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    DOI: 10.1016/j.jphs.2020.08.002

  • A green air assisted-dispersive liquid-liquid microextraction based on solidification of a novel low viscous ternary deep eutectic solvent for the enrichment of endocrine disrupting compounds from water Reviewed International journal

    #Asmaa KamalEl-Deen, @KuniyoshiShimizu

    Journal of Chromatography A   1629   2020.10

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    DOI: 10.1016/j.chroma.2020.461498

  • Diversity and honey properties of stingless bees from meliponiculture in east and north kalimantan, indonesia Reviewed International journal

    Biodiversitas   21 ( 10 )   4623 - 4630   2020.10

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    DOI: 10.13057/biodiv/d211021

  • Isolation and quantification of the plant growth regulator 1-triacontanol from moso bamboo (Phyllostachys pubescens) shoot skin and its compost Reviewed International journal

    Yasuhiro Mori, Akinobu Tanaka, Toshinori Nakagawa, @Yhiya Amen, Yasumitsu Kuwano, Yufu Tanizaki, Shota Tomokiyo, @Kuniyoshi Shimizu

    Agriculture and Forestry   66 ( 3 )   81 - 93   2020.9

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    DOI: 10.17707/AgricultForest.66.3.08

  • Effects and interaction of different interior material treatment and personal preference on psychological and physiological responses in living environment Reviewed International journal

    Sun, Minkai; Nakashima, Taisuke; Yoshimura, Yuri; Honden, Akiyoshi; Nakagawa, Toshinori; Saijo, Hiromi; Watanabe, Yuichiro; Ajimi, Tsuyoshi; Yasunari, Shinji; Yamada, Yuki; Nagano, Jun; Okamoto, Tsuyoshi; Ishikawa, Hiroya; Ohnuki, Koichiro; Fujimoto, Noboru; Shimizu, Kuniyoshi

    Journal of Wood Science   66 ( 1 )   2020.9

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    DOI: 10.1186/s10086-020-01910-2

  • An: In silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19 Reviewed International journal

    RSC Advances   10   29983 - 29998   2020.8

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    DOI: 10.1039/d0ra05265e

  • Postprandial hyperglycemia lowering effect of the isolated compounds from olive mill wastes - An inhibitory activity and kinetics studies on α-glucosidase and α-amylase enzymes Reviewed International journal

    5 ( 32 )   20070 - 20079   2020.8

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    DOI: 10.1021/acsomega.0c01622

  • A new cycloartane triterpene and other phytoconstituents from the aerial parts of Euphorbia dendroides Reviewed International journal

    Ahmed R. Hassan, Ahmed Ashour, @Yhiya Amen, @Maki Nagata, Sayed A. El-Toumy, @Kuniyoshi Shimizu

    Natural Product Research   2020.7

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    DOI: 10.1080/14786419.2020.1800693

  • 雄性不稔スギ爽春の原因遺伝子候補の特徴と花粉形成期に認められた糖代謝異常 Reviewed

    #Nanako Yamasaki, Taisei Horiba, Miho Tamura, Noritsugu Kuramoto , @Kuniyoshi Shimizu, @Atsushi Watanabe

    森林学会誌   102 ( 3 )   2020.6

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  • Effect of porcine placenta extract supplement on skin condition in healthy adult women: A randomized, double-blind placebo-controlled study Reviewed International journal

    @Masumi Nagae, @Maki Nagata, Mitsuhiro Teramoto, Masayuki Yamakawa, Takahiro Matsuki, Koichiro Ohnuki, @Kuniyoshi Shimizu

    Nutrients   12 ( 6 )   1 - 12   2020.6

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    DOI: 10.3390/nu12061671

  • A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity Reviewed International journal

    @Ahmed Ashour, @Yhiya Amen, @Toshinori Nakagawa, @Yasuharu Niwa, Amira Mira, Koichiro Ohnuki, Shinki Murakami, Mitsuko Imao, @Kuniyoshi Shimizu

    Natural Product Research   34 ( 12 )   1750 - 1755   2020.6

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    DOI: 10.1080/14786419.2018.1530231

  • Isolation of new secondary metabolites from gorgonian soft coral Heteroxenia fuscescens collected from Red Sea Reviewed International journal

    Fahd M. Abdelkarem, Ezz-Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Maiki Nagata, Tomofumi Miyamoto, Kuniyoshi Shimizu.

    Phytochemistry Letters   2020.4

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  • The Effect of Eucalyptol on Nursing Home Residents Reviewed International journal

    @Seiko Goto, @Hinako Suzuki, @Toshinori Nakagawa, Kuniyoshi Shimizu

    SCIENTIFIC REPORTS   2020.3

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  • Melanin Synthesis Inhibitors from Olea europeae Reviewed International journal

    #Elkattan, A., @Gohar, A., @Amer, M., @Naeem, Z. M., @Ashour, A., & @Shimizu, K.

    Records of Natural Products   14 ( 2 )   139 - 143   2020.3

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    DOI: 10.25135/rnp.142.19.04.1264

  • Characterization of candidate gene and abnormal of carbohydrate metabolism during pollen development in a male sterility clone, sosyun. [雄性不稔スギ爽春の原因遺伝子候補の特徴と花粉形成期に認められた糖代謝異常] Reviewed International journal

    102 ( 3 )   191 - 197   2020.3

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    DOI: doi:10.4005/jjfs.102.191

  • Prenylated Flavonoids as Antioxidant and Melanin Inhibitors From Stingless Bee (Wallacetrigona incisa) Propolis Reviewed International journal

    @Enos Tangke Arung, @Syafrizal, @Whicliffe Fiernaleonardo Pasedan, @Nataniel Tandirogang, Sukemi, Ahmed E. Allam, Yhiya Amen, Kuniyoshi Shimizu, and @Hiroya Ishikawa

    Natural Product Communications   15 ( 3 )   1 - 6   2020.3

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  • A new pimarane-type diterpene obtained by biotransformation inhibits human HCT-116 colorectal carcinoma through inhibition of LTA4H activity Reviewed International journal

    Amira Mira, Mohamed A. Sabry, @Kuniyoshi Shimizu, Fatma M. Abdel Bar

    Medicinal Chemistry Research   29 ( 4 )   759 - 766   2020.2

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    DOI: 10.1007/s00044-020-02520-9

  • Regular Intake of Japanese Traditional Rice Fermented Beverage, Koji Amazake for 4 weeks Decreases Systolic Blood Pressure A Randomized, Double-blind,Placebo-controlled, Parallel-group Comparative Study Reviewed International journal

    Kenji Kikushima, Toshinori Nakagawa, @Kuniyoshi Shimizu, Koichiro Ohnuki

    Japanese Pharmacology and Therapeutics   48 ( 2 )   305 - 312   2020.2

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  • Effects of Oral Use of Phytosphingosine on Skin Moisturizing in Healthy Adults-A 12-week Double-blind, Randomized, Placebo-controlled Trial Reviewed International journal

    Akemi Nishidc, Miki Shimura, Keiko Ohnuki, @Kuniyoshi Shimizu, Koichiro Ohnuki

    Japanese Pharmacology and Therapeutics   48 ( 2 )   27 - 241   2020.2

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  • Effects and interaction of different interior material treatment and personal preference on psychological and physiological responses in living environment Reviewed International journal

    Minkai Sun, @Taisuke Nakashima, @Yuri Yoshimura, Akiyoshi Honden, Toshinori Nakagawa, Hiromi Saijo, Yuichiro Watanabe, Tsuyoshi Ajimi, Shinji Yasunari, Yuki Yamada, Jun Nagano, Tsuyoshi Okamoto, Hiroya Ishikawa, Koichiro Ohnuki, @Noboru Fujimoto, @Kuniyoshi Shimizu

    Journal of Wood Science   66 ( 1 )   2020.1

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    DOI: 10.1186/s10086-020-01910-2

  • White poplar: Targeted isolation of pancreatic lipase inhibitors Reviewed International journal

    Marwa Elsbaey,@Yhiya Amen,Toshinori Nakagawa,@Kuniyoshi Shimizu

    Industrial Crops and Products   141   2019.12

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    DOI: https://doi.org/10.1016/j.indcrop.2019.111778

  • Application of D-Limonene as a Bio-based Solvent in Low Density-Dispersive Liquid-Liquid Microextraction of Acidic Drugs from Aqueous Samples Reviewed International journal

    #El-Deen, A. K., & @Shimizu, K.

    Analytical Sciences   35 ( 12 )   1385 - 1391   2019.12

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  • Deep eutectic solvent as a novel disperser in dispersive liquid-liquid microextraction based on solidification of floating organic droplet (DLLME-SFOD) for preconcentration of steroids in water samples: Assessment of the method deleterious impact on the environment using Analytical Eco-Scale and Green Analytical Procedure Index Reviewed International journal

    @Asmaa KamalEl-Deen,@KuniyoshiShimizu

    Microchemical Journal   Volume 149 ( 103988 )   2019.11

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    DOI: https://doi.org/10.1016/j.microc.2019.103988

  • Polygonum odoratum essential oil inhibits the activity of mushroom derived tyrosinase Reviewed International journal

    Anne Frances Murray , Hiroki Satooka , Kuniyoshi Shimizu , Warinthorn Chavasiri , Isao Kubo

    Heliyon   5 ( 11 )   2019.11

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    DOI: https://doi.org/10.1016/j.heliyon.2019.e02817

  • Antioxidative activities of 62 wild mushrooms from Nepal and the phenolic profile of some selected species Reviewed International journal

    Tamrakar, S., Tran, H.B., Nishida, M., Kaifuchi, S., Suhara, H., Doi, K., Fukami, K., Parajuli, G.P., @Shimizu, K.

    Journal of Natural Medicines   70 ( 4 )   769 - 779   2019.10

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    DOI: 10.1007/s11418-016-1013-1. Epub 2016 Jun 4.

  • Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives Reviewed

    Dina I.A. Othman, Khalid B. Selim, Magda A.A. El-Sayed, Atif S. Tantawy, Yhiya Amen, Kuniyoshi Shimizu, Tatsuo Okauchi, Mitsuru Kitamura

    Bioorganic and Medicinal Chemistry   27 ( 19 )   2019.10

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    DOI: 10.1016/j.bmc.2019.07.042

  • Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives Reviewed International journal

    Dina I.A. Othman,Khalid B. Selim, Magda A.-A. El-Saye, Atif S. Tantawy, @Yhiya Amen,@Kuniyoshi Shimizu, Tatsuo Okauchi, Mitsuru Kitamura

    Bioorganic & Medicinal Chemistry   27 ( 19 )   2019.10

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    DOI: https://doi.org/10.1016/j.bmc.2019.07.042

  • Anti-oxidant and Aldose Reductase Inhibitory Activity of Piper betle Extracts International journal

    Sri Fatmawati,@Kuniyoshi Shimizu

    Pakistan Academy of Sciences   56 ( 3 )   75 - 82   2019.9

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  • Factors determining soil water repellency in two coniferous plantations on a hillslope Reviewed

    Moein Farahnak, Keiji Mitsuyasu, Kyoichi Otsuki, Kuniyoshi Shimizu, Atsushi Kume

    Forests   10 ( 9 )   2019.9

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    DOI: 10.3390/f10090730

  • Deep eutectic solvent as a novel disperser in dispersive liquid-liquid microextraction based on solidification of floating organic droplet (DLLME-SFOD) for preconcentration of steroids in water samples Assessment of the method deleterious impact on the environment using Analytical Eco-Scale and Green Analytical Procedure Index Reviewed

    Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Microchemical Journal   149   2019.9

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    DOI: 10.1016/j.microc.2019.103988

  • Association Between Serum β-Alanine and Risk of Dementia Reviewed International journal

    188 ( 9 )   2019.9

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    We examined the association between serum concentrations of β-alanine, a metabolite of carnosine and anserine, and the risk of dementia
    in a general population of elderly Japanese persons. In 2007, 1,475 residents of Hisayama, Japan, aged 60–79 years and without dementia were divided into 4 groups according to quartiles of serum β-alanine concentrations (quartile 1, lowest; quartile 4, highest) and followed for a median of 5.3 years. During follow-up, 117 subjects developed all-cause dementia (Alzheimer in 77 cases and vascular dementia in 31).
    The risk of all-cause dementia decreased with increasing serum β-alanine levels after adjustment for potential confounding factors
    (quartile 2, hazard ratio (HR) = 0.73 (95% confidence interval (CI): 0.45, 1.18); quartile 3, HR = 0.50 (95% CI: 0.28, 0.89); quartile 4,
    HR = 0.50 (95% CI: 0.27, 0.92); P = 0.01 for trend). A similar inverse association was observed for Alzheimer disease (quartile 2, HR = 0.78 (95% CI: 0.44, 1.38); quartile 3, HR = 0.53 (95% CI: 0.26, 1.06); quartile 4, HR = 0.53 (95% CI: 0.25, 1.10); P = 0.04 for trend)
    but not for vascular dementia. We found that higher serum β-alanine levels were significantly associated with lower risks of all-cause dementia and Alzheimer disease. Because serum β-alanine levels reflect intakes of carnosine/anserine, higher intakes of carnosine/anserine might be beneficial for the prevention of dementia.

    DOI: https://doi.org/10.1093/aje/kwz116

  • New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus Reviewed International journal

    @Ahmed Ashour,@Yhiya Amen,@Ahmed E.Allam,@Takashi Kudo,@Maki Nagata, Koichiro Ohnuki,@Kuniyoshi Shimizu

    Phytochemistry Letters   32   10 - 14   2019.8

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    DOI: 10.1016/j.phytol.2019.04.017

  • Melanogenesis Inhibitors from the Endophytic Fungus Aspergillus amstelodami Reviewed International journal

    @Elsbaey, M., @Sallam, A., @El-Metwally, M., @Nagata, M., @Tanaka, C., @Shimizu, K., & @Miyamoto, T.

    Chemistry and Biodiversity   16 ( 8 )   2019.8

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    DOI: 10.1002/cbdv.201900237

  • 黒ニンニク含有サプリメント摂取による肝機能保護作用 プラセボ対照・二重盲検・ランダム化比較試験 Invited Reviewed International journal

    河崎 祐樹, 八木 香奈子, 後藤 純平, @清水 邦義, 大貫 宏一郎

    日本栄養・食糧学会誌   70 ( 3 )   109 - 115   2019.8

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  • リンゴ酸およびマグネシウム含有サプリメントの摂取がいびきを自覚する健常者の睡眠の質に与える有効性ープラセボ対照・二重盲検・ランダム化・群間比較試験ー Reviewed

    後藤純平,中川かおり,大貫啓子,@清水邦義,大貫宏一郎

    新薬と臨牀   68 ( 8 )   16 - 30   2019.8

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  • Anti-allergic activity of lotus root (Nelumbo nucifera) powder in TDI-sensitized nasal allergy model mice Reviewed International journal

    Mayumi Kaneyasu, @Maki Nagata, @Hiromi Ikeda, Koichiro Ohnuki ,@ Kuniyoshi Shimizu

    Food and Agricultural Immunology   30 ( 1 )   968 - 978   2019.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Anti-allergic activity of polyphenolic compounds isolated from olive mill wastes Reviewed International journal

    Rogers Mwakalukwa,@Ahmed Ashour,@Yhiya Amenac,@Yasuharu Niwa,@Sonam Tamrakara,@Tomofumi Miyamoto,@Kuniyoshi Shimizu

    Journal of Functional Foods   58   207 - 217   2019.7

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    DOI: 10.1016/j.jff.2019.04.058

  • Antioxidant and Antimelanogenesis Activities of Glyasperin A From Macaranga pruinosa Leaves Reviewed International journal

    @Arung E.T., @Sinamabela J.R., @Rosamah E., @Kusuma I.W., @Kuspradini H., @Alam A.E., @Amen Y., #Tanaka H., #Satria D., @Shimizu K., @Ishikawa H.

    Natural Product Communications   14 ( 7 )   2019.7

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    DOI: 10.1177/1934578X19867192

  • ジャパン・コスメティックセンターとの化粧品プロジェクト 佐賀県産農産物の魅力を掘り起こすーコスメティック原料としての潜在能力 Invited Reviewed

    @清水邦義、@中川敏法

    FRAGRANCE JOURNAL   47 ( 7 )   23 - 30   2019.7

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  • A new HPLC-DAD method for the concurrent determination of hydroquinone, hydrocortisone acetate and tretinoin in different pharmaceuticals for melasma treatment Reviewed International journal

    Fawzia Ibrahim, Mohie K. Sharaf El-Din, Asmaa Kamal El-Deen, @Kuniyoshi Shimizu

    Journal of chromatographic science   57 ( 6 )   495 - 501   2019.7

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    DOI: 10.1093/chromsci/bmz020

  • スギの無垢材を内装に用いた室内空間が人の睡眠に及ぼす影響 Reviewed

    孫旻愷,本傳晃義,羽賀栄理子,中島大輔,吉村友里,西條裕美,鷲岡ゆき,松本清,井隼経子,渡邉雄一郎,安心院剛,安成信次,山田祐樹,永野 純,岡本 剛,石川洋哉,大貫宏一郎,藤本登留,清水邦義

    木材工業   74 ( 7 )   2019.7

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    As a construction material, Sugi (Cryptomeria japonica) is widely used in Japan. Present study focused on how wooden dwelling spaces with Sugi wood material influence quality of human sleep. To clarify this, Room A where naturally processed Sugi wood boards were used for the interiors and the Room B where chemically processed wood materials comprised of bonded or coated woods were used for the interiors were investigated for comparison. Volatile organic compounds (mainly sesqui-terpenes) emitted from both rooms were analyzed by Gas Chromatography/Mass Spectrometry. Ten participants were asked to take a sleep in the two rooms, respectively. Salivary stress markers, sleep time, blood pressure, questionnaires were measured. Humidity and temperature of the both rooms were recorded. The participants’ lifestyles were also investigated. Compared to several characters of Room B, humidity of Room A was lower, and concentration of sesqui-terpenes emitted from Room A were higher. Participants felt more “natural” in Room A. Participant with poor daily sleep quality showed higher morning diastolic pressure only when participants slept in Room B. These results indicate that, high emitting of sesqui-terpenes, high moisture-absorption performance or the combination of them of naturally processed Sugi wood can help people prevent diastolic pressure increasing in the morning caused by low sleep quality.

  • Increase in muscle endurance in mice by dietary Yamabushitake mushroom (Hericium erinaceus) possibly via activation of PPARδ Reviewed International journal

    90 ( 6 )   781 - 789   2019.6

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    Skeletal muscle fiber is largely classified into two types: type 1 (slow‐twitch) and type 2 (fast‐twitch) fibers. Meat quality and composition of fiber types are thought to be closely related. Previous research showed that overexpression of constitutively active peroxisome proliferator‐activated receptor (PPAR)δ, a nuclear receptor present in skeletal muscle, increased type 1 fibers in mice. In this study, we found that hexane extracts of Yamabushitake mushroom (Hericium erinaceus) showed PPARδ agonistic activity in vitro. Eight‐week‐old C57BL/6J mice were fed a diet supplemented with 5% (w/w) freeze‐dried Yamabushitake mushroom for 24 hr. After the treatment period, the extensor digitorum longus (EDL) muscles were excised. The Yamabushitake‐supplemented diet up‐regulated the PPARδ target genes Pdk4 and Ucp3 in mouse skeletal muscles in vivo. Furthermore, feeding the Yamabushitake‐supplemented diet to mice for 8 weeks resulted in a significant increase in muscle endurance. These results indicate that Yamabushitake mushroom contains PPARδ agonistic ligands and that dietary intake of Yamabushitake mushroom could activate PPARδ in skeletal muscle of mice. Unexpectedly, we observed no significant alterations in composition of muscle fiber types between the mice fed control and Yamabushitake‐supplemented diets.

    DOI: 10.1111/asj.13199

  • Chemical components and antioxidant activities of methanol extract of Syzygium polycephalum Miq. stem bark (Myrtaceae) Reviewed International journal

    Tukiran, Andika Pramudya Wardana, Nurul Hidajati, @Kuniyoshi Shimizu

    Indian Journal of Natural Products and Resources   10 ( (2) )   127 - 136   2019.6

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  • プラセンタエキス原末含有サプリメントによる健常成人女性の不定愁訴改善作用 プラセボ対照・二重盲検・ランダム化・クロスオーバー比較試験 Reviewed International journal

    後藤 純平, Supartini Atin, 大貫 啓子, 西尾 朋恵, @清水 邦義, 大貫 宏一郎

    新薬と臨牀   68 ( 6 )   781 - 793   2019.6

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  • α-Glucosidase inhibitory activity of resin from sakhalin fir tree (abies sachalinensis) and its bioactive compounds Reviewed International journal

    14 ( (6) )   2019.6

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    This study investigated in vitro the α-glucosidase inhibitory activity of resin from the Sakhalin fir tree (Abies sachalinensis). The resin showed extremely high activity (IC50 of 17.3 µg/mL). We isolated 8 compounds from the resin and identified them. All of the compounds isolated from A. sachalinensis resin are reported for the first time in the present study. In an α-glucosidase inhibitory assay, 6 compounds—(holophyllane C (1), (−) -(24 E)-23-oxo-3,4- seco-9βH-lanosta-4(28),6,8(14),24-tetraen-3,26-dioic acid (2), abiesonic acid (3), (−)-(24 E)-23-oxo-3,4- seco-9β H-lanosta-4(28),7,24-triene-3,26-dioic acid (4), 3,4-seco-4(28),6,8(14),22Z,24-mariesapentaen-26,23-olide-3-oic acid (5), and (−)-abiesonic acid 3-methyl ester (6))—showed high activity (their IC50 values were 25.1, 20.9, 82.4, 20.5, 27.3, and 20.5 µg/mL, respectively). These compounds should contribute to the resin’s α-glucosidase inhibitory activity. From an industrial point of view, these findings provide new data to support that the resin of A. sachalinensis is a rich source of α-glucosidase inhibitors, which are highly valuable for their potential to be developed as functional health foods.

    DOI: 10.1177/1934578X19858460

  • きのこの健康機能に関するデータベースの構築 〜ネパールのきのこを例として〜 Reviewed International journal

    @永田 真紀 Sonam Tamrakar @清水 邦義

    35巻 ( vol.13 )   2019.6

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  • A Pilot Study on the Effects of Chrysanthemum Scent on Memory and Mood Reviewed International journal

    Kilonzi Francisca, Xuting Shen, @Toshihori Nakagawa, Thomas Gianfagna,@ Kuniyoshi Shimizu, Seiko Goto

    JOURNAL OF THERAPEUTIC HORTICULTURE   XXIX ( 1 )   11 - 23   2019.6

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  • A new glucoside with a potent α-glucosidase inhibitory activity from Lycium schweinfurthii Reviewed International journal

    2019.6

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    DOI: https://doi.org/10.1080/14786419.2019.1616730

  • Mass spectrometry-based untargeted metabolomics and α-glucosidase inhibitory activity of lingzhi (ganoderma lingzhi) during the developmental stages Reviewed International journal

    24 ( (11) )   2019.5

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    Lingzhi is a Ganoderma mushroom species which has a wide range of bioactivities. Analysis of the changes in metabolites during the developmental stages of lingzhi is important to understand the underlying mechanism of its biosynthesis, as well as its bioactivity. It may also provide valuable information for the cultivation efficiency of lingzhi. In this study, mass spectrometry based untargeted metabolomics was carried out to analyze the alteration of metabolites during developmental stages of lingzhi. Eight developmental stages were categorized on the basis of morphological changes; starting from mycelium stage to post-mature stage. GC/MS and LC/MS analyses along with multivariate analysis of lingzhi developmental stages were performed. Amino acids, organic acids, sugars, polyols, fatty acids, fatty alcohols, and some small polar metabolites were extracted as marker metabolites from GC/MS analysis, while, lanostane-type triterpenoids were observed in LC/MS analysis of lingzhi. The marker metabolites from untargeted analysis of lingzhi developmental stages were correlated with the α-glucosidase inhibitory activity. Two metabolites, compounds 34 and 35, were identified as potential contributors of the α-glucosidase inhibitory activity. The current result shows that some metabolites are involved in the developmental process and α-glucosidase inhibitory activity of lingzhi.

    DOI: 10.3390/molecules24112044.

  • Association Between Serum β-Alanine and Risk of Dementia The Hisayama Study Reviewed International journal

    188 ( 9 )   1637 - 1645   2019.5

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    We examined the association between serum concentrations of β-alanine, a metabolite of carnosine and anserine, and the risk of dementia in a general population of elderly Japanese persons. In 2007, 1,475 residents of Hisayama, Japan, aged 60–79 years and without dementia were divided into 4 groups according to quartiles of serum β-alanine concentrations (quartile 1, lowest; quartile 4, highest) and followed for a median of 5.3 years. During follow-up, 117 subjects developed all-cause dementia (Alzheimer in 77 cases and vascular dementia in 31).The risk of all-cause dementia decreased with increasing serum β-alanine levels after adjustment for potential confounding factors (quartile 2, hazard ratio (HR) = 0.73 (95% confidence interval (CI): 0.45, 1.18); quartile 3, HR =0.50 (95% CI: 0.28, 0.89); quartile 4, HR = 0.50 (95% CI: 0.27, 0.92); P = 0.01 for trend). A similar inverse association was observed for Alzheimer disease (quartile 2, HR = 0.78 (95% CI: 0.44, 1.38); quartile 3, HR = 0.53 (95% CI:0.26, 1.06); quartile 4, HR = 0.53 (95% CI: 0.25, 1.10); P = 0.04 for trend) but not for vascular dementia. We found that higher serum β-alanine levels were significantly associated with lower risks of all-cause dementia and Alzheimer disease. Because serum β-alanine levels reflect intakes of carnosine/anserine, higher intakes of carnosine/anserine might be beneficial for the prevention of dementia.β-alanine; Alzheimer disease; cohort study; dementia; imidazole dipeptides

    DOI: 10.1093/aje/kwz116

  • Antioxidant and anti-lipase compounds isolated from heartwood of Yakushima native cedar (Cryptomeria japonica) Reviewed International journal

    Journal of Wood Chemistry and Technology   2019.4

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    DOI: https://doi.org/10.1080/02773813.2019.1578806

  • Ursolic Acid Isolated from the Leaves of Loquat (Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5 Reviewed International journal

    Hui Tan,Chong Zhao,Qinchang Zhu,@Yoshinori Katakura,@Hiroyuki Tanaka,,Koichiro Ohnuki,@Kuniyoshi Shimizu

    Journal of Agricaltural and Food Chemistry   67 ( 12 )   3333 - 3340   2019.3

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    DOI: 10.1021/acs.jafc.8b06954

  • Antiallergic Activity of the Wild Mushrooms of Nepal and the Pure Compound Hispidin Reviewed International journal

    Sonam Tamrakar, @Katsuya Fukami, Gopal Prasad Parajuli, @Kuniyoshi Shimizu

    Journal of medicinal food   22 ( 2 )   225 - 227   2019.3

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    DOI: 10.1089/jmf.2018.4267

  • Effect of polyphenols fromVicia faba on lipase activity and melanogenesis Reviewed International journal

    32 ( 16 )   1920 - 1925   2019.3

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    Two new flavonoid glycosides, kaempferol 3-O-α-L-rhamnopyranosyl (1→6) (3′′-acetyl)-β-D-galactopyranoside 1 and kaempferol 3-O-α-L-arabinopyranosyl-5-O-α-L-rhamnopyranoside 2, along with six known ones 3–8 were isolated from the flowers of Vicia faba L. (Fabaceae). Methanol extract and the isolated compounds were tested against lipase and melanogenesis inhibition activities and resulted in that compound 2 showed 53 and 77% lipase inhibition activity in concentrations of 400 and 800 μg/mL, respectively. For melanogenesis, compounds 2, 3 and 4 exhibited potent melanogenesis inhibition activity where the melanin content in melanoma cells was decreased to be about 57.5, 56 and 61%, respectively, with no obvious melanocytotoxicity. The rest of compounds showed weak to moderate activity. The results of melanogenesis inhibition activity of this study suggested the potential use of Vicia faba flowers as a skin-whitening agent and reveal the flowers to be a rich source of important phytochemicals with antilipase and melanogenesis inhibitory activity.

  • Antiallergic Activity of the Wild Mushrooms of Nepal and the Pure Compound Hispidin Reviewed International journal

    Journal of Medicinal Food   2019.2

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  • Lucidumol D, a new lanostane-type triterpene from fruiting bodies of reishi (ganoderma lingzhi) Reviewed International journal

    #Satria, D., @Amen, Y., @Niwa, Y., @Ashour, A., @Allam, A. E., & @Shimizu, K.

    Natural Product Research   33 ( 2 )   189 - 195   2019.2

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    DOI: 10.1080/14786419.2018.1440229

  • Antiallergic Activity of the Wild Mushrooms of Nepal and the Pure Compound Hispidin Reviewed

    Sonam Tamrakar, Katsuya Fukami, Gopal Prasad Parajuli, Kuniyoshi Shimizu

    Journal of medicinal food   22 ( 2 )   225 - 227   2019.2

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    DOI: 10.1089/jmf.2018.4267

  • A New HPLC-DAD Method for the Concurrent Determination of Hydroquinone, Hydrocortisone Acetate and Tretinoin in Different Pharmaceuticals for Melasma Treatment Reviewed International journal

    Journal of Chromatographic Science   2019.1

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  • Mass spectrometry-based untargeted metabolomics and α-glucosidase inhibitory activity of lingzhi (ganoderma lingzhi) during the developmental stages Reviewed

    24 ( 11 )   2019.1

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    Lingzhi is a Ganoderma mushroom species which has a wide range of bioactivities. Analysis of the changes in metabolites during the developmental stages of lingzhi is important to understand the underlying mechanism of its biosynthesis, as well as its bioactivity. It may also provide valuable information for the cultivation efficiency of lingzhi. In this study, mass spectrometry based untargeted metabolomics was carried out to analyze the alteration of metabolites during developmental stages of lingzhi. Eight developmental stages were categorized on the basis of morphological changes; starting from mycelium stage to post-mature stage. GC/MS and LC/MS analyses along with multivariate analysis of lingzhi developmental stages were performed. Amino acids, organic acids, sugars, polyols, fatty acids, fatty alcohols, and some small polar metabolites were extracted as marker metabolites from GC/MS analysis, while, lanostane-type triterpenoids were observed in LC/MS analysis of lingzhi. The marker metabolites from untargeted analysis of lingzhi developmental stages were correlated with the α-glucosidase inhibitory activity. Two metabolites, compounds 34 and 35, were identified as potential contributors of the α-glucosidase inhibitory activity. The current result shows that some metabolites are involved in the developmental process and α-glucosidase inhibitory activity of lingzhi.

    DOI: 10.3390/molecules24112044

  • Improvement of cognitive functions by oral intake of Hericium erinaceus Reviewed

    Yuusuke Saitsu, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki

    Biomedical research (Tokyo, Japan)   40 ( 4 )   125 - 131   2019.1

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    DOI: 10.2220/biomedres.40.125

  • Effects of panax ginseng-containing tea on cognitive performance in adolescence-a randomized, double-blinded, placebo-controlled parallel comparison trial- Reviewed

    Rie Takae, Junpei Goto, Koichiro Ohnuki, Akemi Nishide, Keiko Ohnuki, Daigo Sato, Kuniyoshi Shimizu

    Japanese Pharmacology and Therapeutics   47 ( 3 )   485 - 491   2019.1

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  • Antioxidant and anti-lipase compounds isolated from heartwood of Yakushima native cedar (Cryptomeria japonica) Reviewed

    Toshinori Nakagawa, Ahmed Ashour, Yhiya Amen, Koichiro Ohnuki, Noboru Fujimoto, Kuniyoshi Shimizu

    Journal of Wood Chemistry and Technology   2019.1

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    DOI: 10.1080/02773813.2019.1578806

  • Anti-allergic activity of lotus root (Nelumbo nucifera) powder in TDI-sensitized nasal allergy model mice Reviewed

    Mayumi Kaneyasu, Maki Nagata, Hiromi Ikeda, Koichiro Ohnuki, Kuniyoshi Shimizu

    Food and Agricultural Immunology   30 ( 1 )   968 - 978   2019.1

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    DOI: 10.1080/09540105.2019.1651255

  • A new glucoside with a potent α-glucosidase inhibitory activity from Lycium schweinfurthii Reviewed

    2019.1

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    A new glucoside, 3-methoxy-4-O-β-D-glucopyranosyl-methyl benzoate, has been isolated from Lycium schweinfurthii along with five known compounds through bioactivity guided fractionation of the total plant methanolic extract towards α-glucosidase inhibitory activity. All the isolated compounds were tested for their inhibitory effect on α-glucosidase enzyme. As a result, four of them showed a potent inhibitory activity and thus constitute a therapeutic approach to decrease postprandial hyperglycemia in diabetic patients.

    DOI: 10.1080/14786419.2019.1616730

  • A new HPLC-DAD method for the concurrent determination of hydroquinone, hydrocortisone acetate and tretinoin in different pharmaceuticals for melasma treatment Reviewed

    Fawzia Ibrahim, Mohie K. Sharaf El-Din, Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Journal of chromatographic science   57 ( 6 )   495 - 501   2019.1

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    DOI: 10.1093/chromsci/bmz020

  • Two new polyhydroxylated steroids from Egyptian soft coral Heteroxenia fuscescens (Fam.; Xeniidae) Reviewed International journal

    Abdelkarem, F.M., Desoky, E.-E.K., Nafady, A.M., Allam, A.E., Mahdy, A., Ashour, A., Mohamed, G.A., Miyamoto, T., @Shimizu, K.

    Natural Product Research   2019.1

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    DOI: 10.1080/14786419.2019.1624958.

  • Effects of panax ginseng-containing tea on cognitive performance in adolescence-a randomized, double-blinded, placebo-controlled parallel comparison trial- Reviewed International journal

    @Takae, R., Goto, J., Ohnuki, K., Nishide, A., Ohnuki, K., Sato, D., @Shimizu, K.

    Japanese Pharmacology and Therapeutics   47 ( 3 )   485 - 491   2019.1

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  • Effect of wood, bark and leaf extracts of Macaranga trees on cytotoxic activity in some cancer and normal cell lines Reviewed International journal

    @Enos Tangke Arung, @Rudianto Amirta ,Qinchang Zhu, Yhiya Amen, Kuniyoshi Shimizu

    Journal of the Indian Academy of Wood Science   15 ( 2 )   115 - 119   2018.12

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    DOI: 10.1007/s13196-018-0215-4

  • ヌックマム含有サプリメントの日本人成人男女における血圧降下作用 二重盲検ランダム化比較試験による検討 Reviewed International journal

    後藤 純平, 大貫 啓子, 中村 美紀, 稗田 美子, @清水 邦義, 大貫 宏一郎

    新薬と臨牀   67 ( 12 )   1506 - 1516   2018.12

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  • A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity Reviewed International journal

    Ahmed Ashour, Yhiya Amen, @Toshinori Nakagawa, @Yasuharu Niwa, Amira Mira, Koichiro Ohnuki, Shinki Murakami, Mitsuko Imao @Kuniyoshi Shimizu

    Natural Product Research   2018.12

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  • 佐賀県で生産されたシキミ(Illicium anisatum)の機能性食品および化粧品素材としての機能性評価 Reviewed

    中川敏法、西條裕美、石川洋哉、泥谷慎司、香月優、岩元彬、鶴田裕美、柘植圭介、吉村臣史、大貫宏一郎、清水邦義

    日本食品保蔵科学会誌   44 ( 6 )   303 - 308   2018.11

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  • Forsskamide, A New Ceramide from Aerial Parts of Forsskaole Reviewed International journal

    H.K. Assaf, A.M. Nafady, A. E. Allam, A.N.E. Hamed, M.S. Kamel,@K. Shimizu

    Natural Product Research   32 ( 20 )   2452 - 2456   2018.10

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    DOI: 10.1080/14786419.2017.1419234

  • Could Araucaria heterophylla resin extract be used as a new treatment for toxoplasmosis? Reviewed International journal

    El-Tantawy, N.L., Soliman, A.F., Abdel-Magied, A., Ghorab, D., Khalil, A.T., Naeem, Z.M.,@Shimizu, K., El-Sharkawy, S.H.

    Experimental Parasitology   195   44 - 53   2018.10

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    DOI: 10.1016/j.exppara.2018.10.003. Epub 2018 Oct 16.

  • 健康な成長期男女に対するアルギニン含有成長系サプリメント摂取における安全性の検証 Reviewed International journal

    上野 加奈子, 大貫 啓子, 後藤 純平, 佐藤 大吾, @清水 邦義, 大貫 宏一郎

    新薬と臨牀   67 ( 9 )   1075 - 1084   2018.9

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  • Characterization of Angiotensin-Converting Enzyme Inhibitory Activity of X-Hyp-Gly-Type Tripeptides Importance of Collagen-Specific Prolyl Hydroxylation Reviewed

    Yuki Taga, Osamu Hayashida, Ahmed Ashour, Yhiya Amen, Masashi Kusubata, Kiyoko Ogawa-Goto, Kuniyoshi Shimizu, Shunji Hattori

    Journal of Agricultural and Food Chemistry   66 ( 33 )   8737 - 8743   2018.8

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    DOI: 10.1021/acs.jafc.8b03648

  • Comparative study of two different chromatographic approaches for quantification of hydrocortisone acetate and pramoxine hydrochloride in presence of their impurities Reviewed International journal

    F. Ibrahim, A.K. EI-Deen,@K. Shimizu

    Journal of Food and Drug Analysis   26 ( 3 )   1160 - 1170   2018.7

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    DOI: https://doi.org/10.1016/j.jfda.2017.12.008

  • Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes Reviewed

    Zhao Chong, Haruka Matsuo, Mai Kuroda, Shuntaro Yamashita, Gopal Prasad Parajuli, Hira Kaji Manandhar, Kuniyoshi Shimizu, Yoshinori Katakura

    Cytotechnology   1 - 8   2018.6

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    DOI: 10.1007/s10616-018-0229-1

  • Changes in triterpenoids and polysaccharides content in Ganoderma lingzhi at different growth stages Reviewed International journal

    @T. Nakagawa, Q. Zhu, S. Tamrakar, Y. Amen, Y. Mori, H. Suhara, S. Kaneko, H. Kawashima, K. Okuzono, Y. Inoue, K. Ohnuki, @K. Shimizu

    Journal of Natural Medicines   72 ( 3 )   734 - 744   2018.6

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  • Protective effects of total alkaloids from Dendrobium crepidatum against LPS-induced acute lung injury in mice and its chemical components Reviewed

    Yang Hu, Jie Ren, Lei Wang, Xin Zhao, Mian Zhang, Kuniyoshi Shimizu, Chaofeng Zhang

    Phytochemistry   149   12 - 23   2018.5

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    DOI: 10.1016/j.phytochem.2018.02.006

  • Microbial transformation of the labdane diterpene 13-epi-cupressic acid Reviewed International journal

    A.F. Soliman, Z.M. Naeem, A.T. Khalil, @K. Shimizu, S. H. El-Sharkawy

    World J. Pharm. Sci   6 ( 5 )   61 - 69   2018.5

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  • スギの無垢材を内装に用いた室内空間における人滞在時の吸湿作用の検証 Reviewed

    @清水邦義,#本傳晃義,#奥田 拓,@羽賀栄理子,中島大輔,@鷲岡ゆき,@松本 清,@山本 篤,@吉村友里,@井隼経子,渡邉雄一郎,安心院剛, 安成信次,@山田祐樹,@永野 純,@岡本 剛,石川洋哉,大貫宏一郎,@藤本登留

    木材工業   73 ( 5 )   187 - 192   2018.5

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    This study focused on the humidity-control performance of the wooden dwelling spaces, which is related to the habitability. To evaluate the moisture-absorption performance in a condition close to real life, the room temperature and relative humidity were measured in a room using naturally processed sugi (Cryptomeria japonica ) wood boards (Room A) and a room using chemically processed wood materials(Room B)as interior materials while subjects were asleep. The interior materials of Room A were free from chemical processing and those of Room B were comprised of bonded or coated woods.
    The results obtained from this study during 2014 and 2015 demonstrated that the Room A showed
    higher moisture-absorption performance than the Room B.

    Repository Public URL: http://hdl.handle.net/2324/1932323

  • Stability-indicating spectrofluorimetric method with enhanced sensitivity for determination of vancomycin hydrochloride in pharmaceuticals and spiked human plasma Application to degradation kinetics Reviewed

    Mohie Khaled Sharaf El-Din, Fawzia Ibrahim, Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Journal of Food and Drug Analysis   26 ( 2 )   834 - 841   2018.4

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    DOI: 10.1016/j.jfda.2017.06.005

  • Changes in content of triterpenoids and polysaccharides in Ganoderma lingzhi at different growth stages Reviewed

    Toshinori Nakagawa, Qinchang Zhu, Sonam Tamrakar, Yhiya Amen, Yasuhiro Mori, Hiroto Suhara, Shuhei Kaneko, Hiroko Kawashima, Kotaro Okuzono, Yoshiyuki Inoue, Koichiro Ohnuki, Kuniyoshi Shimizu

    Journal of Natural Medicines   1 - 11   2018.4

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    DOI: 10.1007/s11418-018-1213-y

  • Application of quinone-based fluorophore and native fluorescence for the spectrofluorimetric determination of agomelatine in dosage form Identification of acidic and alkaline- induced degradation products by LC–MS/TOF Reviewed

    33 ( 1 )   225 - 231   2018.2

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    Three spectrofluorimetric methods were developed for agomelatine (AGM) determination in commercial tablets. Method A is based on measuring the native fluorescence of AGM aqueous solution at 230/360 nm. Methods B and C are based on the formation of a charge transfer complex between AGM and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and 7,7,8,8-tetracyanoquinodimethane (TCNQ) with measurement of the formed fluorophore at 365/475 nm and 250/304 nm, respectively. The relative fluorescence intensity (RFI) of AGM–DDQ complex was greatly enhanced in the presence of methyl-β-cyclodextrin (CD). The methods were linear over the concentration ranges of 0.015–0.5, 0.5–8.0, 0.09–6.0 and 0.05–0.2 μg/ml for AGM-native fluorescence, AGM–DDQ, AGM–DDQ–CD and AGM–TCNQ complexes, respectively with excellent correlation coefficients (r = 0.9999). The methods were validated as per the International Conference on Harmonization (ICH) guidelines and all validation requirements were satisfied. The developed methods were extended to the analysis of AGM in commercial tablets. Furthermore, the stability of AGM was studied under different stress conditions (alkaline, acidic, oxidative and photolytic). The potential alkaline and acidic degradation products were identified by LC–MS/TOF.

    DOI: 10.1002/bio.3405

  • 睡眠誘導効果をもつ(-)-酢酸ボルニルの睡眠促進効果ならびに肌質改善効果 Reviewed International journal

    @清水 邦義, @孫 旻がい, 松本 清, @本傳 晃義, 大貫 宏一郎

    46 ( 2 )   24 - 30   2018.2

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  • Chemical components and antioxidant activities of methanol extract of syzygium polycephalum miq. stem bark (Myrtaceae) Reviewed International journal

    Tukiran,Andika Pramudya Wardana,Nurul Hidajati,@Kuniyoshi Shimizu

    Indonesian Journal of Chemisty   18 ( 1 )   26 - 34   2018.2

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    DOI: 10.22146/ijc.25467

  • Mogroside IVE attenuates experimental liver fibrosis in mice and inhibits HSC activation through downregulating TLR4-mediated pathways Reviewed

    Fengyan Cao, Yunfang Zhang, Weiguang Li, Kuniyoshi Shimizu, Haifeng Xie, Chaofeng Zhang

    International Immunopharmacology   55   183 - 192   2018.2

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    DOI: 10.1016/j.intimp.2017.12.023

  • Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi) Reviewed

    Dedi Satria, Yhiya Amen, Yasuharu Niwa, Ahmed Ashour, Ahmed E. Allam, Kuniyoshi Shimizu

    Natural Product Research   1 - 6   2018.2

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    DOI: 10.1080/14786419.2018.1440229

  • Anti-Angiogenic Activity of Rotenoids from the Stems of Derris trifoliata Reviewed

    Yanisa Mittraphab, Nattaya Ngamrojanavanich, Kuniyoshi Shimizu, Kiminori Matsubara, Khanitha Pudhom

    Planta Medica   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-0044-100797

  • An Ellagic Acid Derivative and Its Antioxidant Activity of Chloroform Extract of Stem Bark of Syzygium polycephalumMiq. (Myrtaceae) Reviewed International journal

    18 ( 1 )   26 - 34   2018.1

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    The investigation of the Syzygium polycephalum Miq. (Myrtaceae) aimed to assess the phytochemical contents and antioxidant activity of the chloroform fraction. In this study, the fraction was obtained from methanol extract of S. polycephalum stem bark partitionated by chloroform. An ellagic acid derivative was successively isolated from the chloroform fraction. The molecular structure of isolated compound was elucidated and established as 3,4,3’-tri-O-methylellagic acid through extensive spectroscopic studies including UV-Vis, FTIR, NMR and LC-MS analyses and by comparison with literature data. The finding of the isolated compound is the first time from the plant, although the isolated compound previously have been found in the other Syzygium species such as S. cumini together with ellagic acid and 3,3’-di-O-methylellagic acid. The chloroform fraction, isolated compound, and vitamin C showed antioxidant activity against 2,2’-diphenyl-1-picrylhydrazyl (DPPH) with IC50 value of 163.6, 72.1, and 11.5 μg/mL, respectively.

  • Sleep enhancement by saffron extract in randomized control trial Reviewed

    Akemi Nishide, Takashi Fujita, Yoshiteru Nagaregawa, Yukihiro Shoyama, Keiko Ohnuki, Kuniyoshi Shimizu, Tuneyuki Yamamoto, Tomonari Watanabe, Koichiro Ohnuki

    Japanese Pharmacology and Therapeutics   46 ( 8 )   1407 - 1415   2018.1

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  • Biological activities of extracts from different parts of two cultivars of Prunus persica 'akatsuki' and 'fastigiata' Reviewed

    Toshinori Nakagawa, Ahmed E. Allam, Koichiro Ohnuki, Kuniyoshi Shimizu

    Natural Product Communications   13 ( 10 )   1293 - 1296   2018.1

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  • Comparative study of two different chromatographic approaches for quantitation of hydrocortisone acetate and pramoxine hydrochloride in presence of their impurities Reviewed

    Fawzia Ibrahim, Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Journal of Food and Drug Analysis   2018.1

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    DOI: 10.1016/j.jfda.2017.12.008

  • Forsskamide, a new ceramide from aerial parts of Forsskaolea tenacissima Linn. Reviewed

    Hamdy K. Assaf, Alaa M. Nafady, Ahmed E. Allam, Ashraf N.E. Hamed, Mohamed S. Kamel, Kuniyoshi Shimizu

    Natural Product Research   1 - 5   2017.12

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    DOI: 10.1080/14786419.2017.1419234

  • Melanogenesis inhibitors from Coix lacryma-jobi seeds in B16-F10 melanoma cells Reviewed International journal

    Yhiya Amen, Enos Tangke Arung, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Ryoji Fujimoto, Takahiro Goto, Kuniyoshi Shimizu

    Natural Product Research   31 ( 23 )   2712 - 2718   2017.12

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    DOI: 10.1080/14786419.2017.1292270

  • Bacterial expression of a single-chain variable fragment (scFv) antibody against ganoderic acid a A cost-effective approach for quantitative analysis using the scfv-based enzyme-linked immunosorbent assay Reviewed International journal

    Gorawit Yusakul, Poomraphie Nuntawong, Seiichi Sakamoto, Pahweenvaj Ratnatilaka Na Bhuket, Toshitaka Kohno, Nao Kikkawa, Pornchai Rojsitthisak, Kuniyoshi Shimizu, Hiroyuki Tanaka, Satoshi Morimoto

    Biological and Pharmaceutical Bulletin   40 ( 10 )   1767 - 1774   2017.10

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  • Application of quinone-based fluorophore and native fluorescence for the spectrofluorimetric determination of agomelatine in dosage form: Identification of acidic and alkaline- induced degradation products by LC–MS/TOF Reviewed International journal

    33 ( 1 )   223 - 231   2017.10

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    Three spectrofluorimetric methods were developed for agomelatine (AGM) determination in commercial tablets. Method A is based on measuring the native fluorescence of AGM aqueous solution at 230/360 nm. Methods B and C are based on the formation of a charge transfer complex between AGM and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and 7,7,8,8-tetracyanoquinodimethane (TCNQ) with measurement of the formed fluorophore at 365/475 nm and 250/304 nm, respectively. The relative fluorescence intensity (RFI) of AGM-DDQ complex was greatly enhanced in the presence of methyl-β-cyclodextrin (CD). The methods were linear over the concentration ranges of 0.015-0.5, 0.5-8.0, 0.09-6.0 and 0.05-0.2 μg/ml for AGM-native fluorescence, AGM-DDQ, AGM-DDQ-CD and AGM-TCNQ complexes, respectively with excellent correlation coefficients (r = 0.9999). The methods were validated as per the International Conference on Harmonization (ICH) guidelines and all validation requirements were satisfied. The developed methods were extended to the analysis of AGM in commercial tablets. Furthermore, the stability of AGM was studied under different stress conditions (alkaline, acidic, oxidative and photolytic). The potential alkaline and acidic degradation products were identified by LC-MS/TOF.

  • An Active Drimane-Type Lactone from Polygonum jucundum Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice Through TLR4-MAPKs Signaling Pathway Reviewed

    Yang Hu, Lijun Tao, Hui Tan, Mian Zhang, Kuniyoshi Shimizu, Fei Zhang, Chaofeng Zhang

    Inflammation   40 ( 4 )   1204 - 1213   2017.8

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    DOI: 10.1007/s10753-017-0563-z

  • Effect of polyphenols from Vicia faba L on lipase activity and melanogenesis Reviewed

    Ahmed E. Allam, Alaa M. Nafady, Toshinori Nakagawa, Naomichi Takemoto, Kuniyoshi Shimizu

    Natural Product Research   1 - 6   2017.8

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    DOI: 10.1080/14786419.2017.1359169

  • Antibacterial activity of Nepalese wild mushrooms against Staphylococcus aureus and Propionibacterium acnes Reviewed

    Sonam Tamrakar, Marina Nishida, Yhiya Amen, Hai Bang Tran, Hiroto Suhara, Katsuya Fukami, Gopal Prasad Parajuli, Kuniyoshi Shimizu

    Journal of Wood Science   63 ( 4 )   379 - 387   2017.8

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    DOI: 10.1007/s10086-017-1636-1

  • An ecofriendly green liquid chromatographic method for simultaneous determination of nicotinamide and clindamycin phosphate in pharmaceutical gel for acne treatment Reviewed

    Fawzia Ibrahim, Asmaa Kamal El-Deen, Samah Abo El Abass, Kuniyoshi Shimizu

    Journal of Food and Drug Analysis   25 ( 3 )   741 - 747   2017.7

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    DOI: 10.1016/j.jfda.2016.09.009

  • Rho-kinase inhibitors from adlay seeds Reviewed

    Yhiya Amen, Qinchang Zhu, Hai Bang Tran, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Ryoji Fujimoto, Takahiro Goto, Kuniyoshi Shimizu

    Natural Product Research   1 - 5   2017.7

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    DOI: 10.1080/14786419.2017.1354183

  • Anti-obesity activity of Yamabushitake (Hericium erinaceus) powder in ovariectomized mice, and its potentially active compounds Reviewed

    Eri Hiraki, Shoko Furuta, Rika Kuwahara, Naomichi Takemoto, Toshiro Nagata, Taiki Akasaka, Bungo Shirouchi, Masao Sato, Koichiro Ohnuki, Kuniyoshi Shimizu

    Journal of Natural Medicines   71 ( 3 )   482 - 491   2017.7

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    DOI: 10.1007/s11418-017-1075-8

  • Anti-influenza effects of Ganoderma lingzhi An animal study Reviewed

    Qinchang Zhu, Yhiya M. Amen, Koichiro Ohnuki, Kuniyoshi Shimizu

    Journal of Functional Foods   34   224 - 228   2017.7

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    DOI: 10.1016/j.jff.2017.04.040

  • The potential of triterpenoids from loquat leaves (Eriobotrya japonica) for prevention and treatment of skin disorder Reviewed

    Hui Tan, Tamrakar Sonam, Kuniyoshi Shimizu

    International Journal of Molecular Sciences   18 ( 5 )   2017.5

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    DOI: 10.3390/ijms18051030

  • Tubulin polymerization stimulating-activity of Ganoderma triterpenoids. Invited Reviewed International journal

    T. Kohno, T. Hai-Bang, Q. Zhu, S. Sakamoto, H. Tanaka, S. Morimoto, Shimizu K

    J Nat Med   71 ( 2 )   457 - 462   2017.4

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  • Anti-allergic triterpenes isolated from olive milled waste Reviewed

    Asuka Kishikawa, Yhiya Amen, Kuniyoshi Shimizu

    Cytotechnology   69 ( 2 )   307 - 315   2017.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10616-016-0058-z

  • Tubulin polymerization-stimulating activity of Ganoderma triterpenoids Reviewed

    Toshitaka Kohno, Tran Hai-Bang, Qinchang Zhu, Yhiya Amen, Seiichi Sakamoto, Hiroyuki Tanaka, Satoshi Morimoto, Kuniyoshi Shimizu

    Journal of Natural Medicines   71 ( 2 )   457 - 462   2017.4

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    DOI: 10.1007/s11418-017-1072-y

  • Partial contribution of Rho-kinase inhibition to the bioactivity of Ganoderma lingzhi and its isolated compounds insights on discovery of natural Rho-kinase inhibitors Reviewed

    Yhiya Amen, Qinchang Zhu, Hai Bang Tran, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Kuniyoshi Shimizu

    Journal of Natural Medicines   71 ( 2 )   380 - 388   2017.4

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    DOI: 10.1007/s11418-016-1069-y

  • Biodegradation of Aldrin and Dieldrin by the White-Rot Fungus Pleurotus ostreatus Reviewed International journal

    Adi Setyo Purnomo, Refdinal Nawfa, Fahimah Martak, Kuniyoshi Shimizu, Ichiro Kamei

    Current Microbiology   74 ( 3 )   320 - 324   2017.3

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    DOI: 10.1007/s00284-016-1184-8

  • 新機能性トウガラシ品種(Capsicum annuum cv. Dangjo)摂取による食後血糖値の上昇抑制効果― プラセボ対照・ランダム化比較・クロスオーバー試験 ― Reviewed

    本傳晃義,浦岡美和,大貫啓子,佐藤大吾,清水邦義,大貫宏一郎

    新薬と臨床   66 ( 3 )   243 - 248   2017.3

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  • Partial contribution of Rho-kinase inhibition to the bioactivity of Ganoderma lingzhi and its isolated compounds; Insights on discovery of natural Rho-kinase inhibitors Reviewed International journal

    Yhiya Amen, Qinchang Zhu, Hai-Bang Tran, Mohamed S. Afifi, Ahmed F. Halim,, Ahmed Ashour, Kuniyoshi Shimizu

    Journal of Natural Medicines   71 ( 2 )   380 - 388   2017.1

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  • ハトムギエキス未含有サプリメントを摂取することにによる成人日本人女性の肌への影響-ランダム化・二重盲検・プラセボ対象比較試験- Reviewed

    奥田拓, 中川敏法, 村野朋哉, 三好悠, 亀井裕人, 佐々木隆雄, 三枝康弘, 和田善行, 湊俊司, 阪井彰一, 千里泰三, 藤本登留, 清水邦義

    木材学会誌   63 ( 5 )   204 - 213   2017.1

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  • 乾燥処理がスギ板材の抽出成分に与える影響 Reviewed

    奥田拓, 中川敏法, 村野朋哉, 三好悠, 亀井裕人, 佐々木隆雄, 三枝康弘, 和田善行, 湊俊司, 阪井彰一, 千里泰三, 藤本登留, 清水邦義

    木材学会誌   63 ( 5 )   204 - 213   2017.1

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  • スギ材を内装材として使用した室内空間における揮発性成分の分析およびその季節変動 Reviewed

    清水邦義 , 吉村友里, 中川敏法, 松本清, 鷲岡ゆき, 羽賀栄理子, 本傳晃義, 中島大輔, 西條裕美, 藤田弘毅, 渡邊雄一郎, 岡本元一, 井上伸史, 安成信次, 永野純, 山田祐樹, 岡本剛, 大貫宏一郎, 石川洋哉, 藤本登留

    木材学会誌   63 ( 3 )   126 - 130   2017.1

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  • Antioxidant activity of Syzygium polynthum extracts Reviewed International journal

    Mutia Devi Hidayati, Taslim Ersam, Kuniyoshi Shimizu, Sri Fatmawati

    Indonesian Journal of Chemistry   17 ( 1 )   49 - 53   2017.1

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    DOI: 10.22146/ijc.23545

  • Micellar HPLC method for simultaneous determination of ethamsylate and mefenamic acid in presence of their main impurities and degradation products Reviewed International journal

    Fawzia Ibrahim, Mohie K.Sharaf El-Din, Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Journal of Chromatographic Science   55 ( 1 )   23 - 29   2017.1

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    DOI: 10.1093/chromsci/bmw143

  • Hepatoprotective activities of the methanol extract of Angelica shikokiana and isoepoxypteryxin against hepatocellular carcinoma Reviewed

    A. Mira, N. Elsherbiny, W. Alkhiary, A. Shebl, H. Tran, Kuniyoshi Shimizu

    Indian Journal of Pharmaceutical Sciences   79 ( 4 )   576 - 584   2017.1

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    DOI: 10.4172/pharmaceutical-sciences.1000265

  • Antiplatelet and Anticoagulant Activities of Angelica shikokiana Extract and Its Isolated Compounds Reviewed

    Amira Mira, Wael Alkhiary, Kuniyoshi Shimizu

    Clinical and Applied Thrombosis/Hemostasis   23 ( 1 )   91 - 99   2017.1

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    DOI: 10.1177/1076029615595879

  • Synthesis, Docking, Cytotoxicity, and LTA4H Inhibitory Activity of New Gingerol Derivatives as Potential Colorectal Cancer Therapy Reviewed International journal

    Mai H. El-Naggar, Amira Mira, Fatma M. Abdel Bar, Kuniyoshi Shimizu, Mohamed M. Amer, Farid A. Badria

    Bioorganic & Medicinal Chemistry   25 ( 3 )   1277 - 1285   2016.12

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  • A phenolic acid and its antioxidant activity from stem bark of chloroform fraction of Syzygium littorale (Blume) amshoff (Myrtaceae) Reviewed International journal

    Tukiran, F.Mahmudah, N. Hidayati, K.Shimizu

    Molekul   11 ( 2 )   180 - 189   2016.11

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  • Improved Biological Activities of Isoepoxypteryxin by Biotransformation Reviewed International journal

    Amira Mira,Wael Alkhiary,Qinchang Zhu, @Toshinori Nakagawa,@Hai-Bang Tran, @Yhiya M. Amen,@Kuniyoshi Shimizu

    Chemistry and Biodiversity   1307 - 1315   2016.10

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  • An update on antitumor activity of Angelica species Reviewed International journal

    Mira, A., @Shimizu, K.

    Medicinal Plants - Recent Advances in Research and Development   363 - 371   2016.10

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  • Acetylcholine esterase inhibitors and melanin synthesis inhibitors from Salvia officinalis Reviewed International journal

    A.Sallam, A.Mira, A.Ashour, Shimizu K

    Phytomedicine   23 ( 10 )   1005 - 1011   2016.9

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  • Biological activities of extracts from different parts of cryptomeria japonica Reviewed International journal

    @Horiba Hiroki,@Nakagawa Toshinori,@Zhu Qinchang,Ashour Ahmed,@Watanabe Atsushi, Shimizu Kuniyoshi

    Natural Product Communications   11 ( 9 )   1337 - 1342   2016.9

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  • An Ecofriendlly Green Liquid Chromatographic Method for Simultaneous Determination of Nicotinamide and Clindamycin phosphate in Pharmaceutical Gel for Acne Treatment Reviewed International journal

    F.Ibrahim, A.K.El-Deen, S.A.El Abass, Shimizu K

    Jounal of Food and Drug Analysis   25 ( 3 )   741 - 747   2016.9

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  • New cytotoxic lanostanoid triterpenes from Ganoderma lingzhi Reviewed International journal

    Y.M.Amen, Q.Zhu, M.S.Afifi, A.Ashour, Shimizu K

    Phytochemistry Letters   17   64 - 70   2016.9

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  • Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma Lingzhi Reviewed International journal

    S.Sakamoto, N.Kikkawa, T.Kohno, Shimizu K, H.Tanaka, S.Morimoto

    Fitoterapia   114   51 - 55   2016.8

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  • Antioxidant activity of Moringa oleifera extracts Reviewed International journal

    16 ( 3 )   297 - 301   2016.8

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    Moringa oleifera have been evaluated for its antioxidant activity. M. oleifera leaves were extracted with methanol, ethyl acetate, dichloromethane and n-hexane. The antioxidant activity of extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay and an improved 2,2’-azino-bis-[3-ethylbenzothiazoline sulphonate] (ABTS) radical cation decolorization assay in vitro. Trolox was used as standard with IC50 5.89 μg/mL in DPPH assay and 3.06 μg/mL in ABTS assay. The methanol extract showed the highest free radical scavenging activity with IC50 value of 49.30 μg/mL in DPPH assay and 11.73 μg/mL in ABTS assay. This study provided that M. oleifera leaves possess antioxidant.

    DOI: https://doi.org/10.22146/ijc.21145

  • Methoxyflavones from New Lingzhi medicinal mushroom, Ganoderma lingzhi (agaricomycetes) Reviewed International journal

    Shimizu, K., Amen, Y.M., Kaifuchi, S.

    International Journal of Medicinal Mushrooms   18 ( 8 )   713 - 719   2016.8

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  • Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells Reviewed International journal

    Yhiya M. Amen, Amira Mira, Hai-Bang Tran, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour,@Kuniyoshi Shimizu

    Journal of Natural Medicines   70 ( 3 )   661 - 666   2016.7

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  • Anti-oxidative Activities of 62 Wild Mushrooms from Nepal and the Phenolic Profile of Some Selected Species Reviewed International journal

    S. Tamrakar, H. B. Tran, M. Nishida, S. Kaifuchi, H. Suhara, K. Doi, K. Fukami, G. P. Parajuli, Shimizu K

    Journal of Natural Medicines   1 - 11   2016.6

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  • In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and Its isolated compounds Reviewed International journal

    M.Amira, Shimizu K

    Pharmacognosy Magazine   11 ( 4 )   564 - 569   2016.6

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  • An LC-MS/MS-SRM method for simultaneous quantification of four representative organosulfur compounds in garlic products Invited Reviewed International journal

    Q. Zhu, K. Kakino, C. Nogami, K. Ohnuki, Shimizu K

    Food Analytical Methods   2016.5

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  • Biological Activities of Oleanolic Acid Derivatives from Calendula officinalis Seeds Reviewed International journal

    Ahmed Zaki,@Ahmed Ashour,@Amira Mira,@Asuka Kishikawa,@Toshinori Nakagawa, @Qinchang Zhu,@Kuniyoshi Shimizu1*

    Phytotherapy Research   30 ( 5 )   835 - 841   2016.5

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  • Hericium erinaceus extracts alter behavioral rhythm in mice Invited Reviewed International journal

    S.Furuta, R.Kuwahara, E.Hiraki, K.Ohnuki, S.Yasuo, K.Shimizu

    Biomedical Research   37 ( 4 )   2016.5

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  • Anti-choline esterase activity of ceramides from the Red Sea Marine Sponge Mycale euplectellioides Invited Reviewed International journal

    R. Abdelhameed, M. S. Elgawish, A. Mira, A. K. Ibrahim, S. A. Ahmed, Shimizu K, K. Yamada

    RSC Advances   6   20422 - 20430   2016.2

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    DOI: 10.1039/C5RA26424C

  • Simultaneous determination of four vasoactive phytochemicals in different pharmaceutical preparations by a simple HPLC-DAD method Invited Reviewed International journal

    F. Ibrahim, M. K. S. El-Din, R. N. El-Shaheny, A. K. El-Deen, Shimizu K

    Analytical Methods   8   1858 - 1866   2016.2

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    DOI: 10.1039/C5AY03003J

  • Multiple uses of essential oil and by-products from various parts of the Yakushima native cedar (Cryptomeria japonica) Invited Reviewed International journal

    T. Nakagawa, Q. Zhu, H. Ishikawa, K. Ohnuki, K. Kakino, N. Horiuchi, H. Shinotsuka, T. Naito, T. Matsumoto, N. Minamisawa, M. Yatagai, Shimizu, K

    Journal of Wood Chemistry and Technology   36 ( 1 )   42 - 55   2016.1

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    DOI: DOI:10.1080/02773813.2015.1057648

  • 福岡県糸島産農産物の抗酸化活性を指標とした機能性評価 Reviewed

    中川敏法,永田敏郎,大貫宏一郎,森高正博,福田晋,清水邦義

    九州大学農学芸誌   71 ( 2 )   29 - 35   2016.1

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  • ハーブティーの便通および体組成に対する効果 Invited Reviewed

    後藤純平、清水邦義、佐藤大吾、大貫宏一郞

    新薬と臨床   65 ( 50 )   707 - 715   2016.1

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  • 脂質への放射線照射による影響 揮発性物質の生成について Reviewed

    南育子,中川敏法,奥野悦生,大貫宏一郎,清水邦義

    九州栄養福祉大学研究紀要   13   153 - 156   2016.1

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  • エミューオイルの機能特性 Reviewed

    南育子,中川敏法,室井由起子,奥野悦生,大貫宏一郎,清水邦義

    九州栄養福祉大学研究紀要   13   149 - 152   2016.1

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  • Detection of ganoderic acid A in Ganoderma lingzhi by an indirect competitive enzyme-linked immunosorbent assay Invited Reviewed International journal

    Sakamoto, S, Kohno, T, Shimizu K, Tanaka, H, Morimoto, S.

    Planta Med   2015.11

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    DOI: 10.1055/s-0042-104202

  • Kibizu concentrated liquid suppresses the accumulation of lipid droplets in 3T3-L1 cells Reviewed

    Chisato Inoue, Tomomi Kozaki, Yukiko Morita, Bungo Shirouchi, Katsuya Fukami, Kuniyoshi Shimizu, Masao Sato, Yoshinori Katakura

    Cytotechnology   67 ( 4 )   721 - 725   2015.8

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    DOI: 10.1007/s10616-015-9849-x

  • GC-MS分析のための脂質の誘導体化 Reviewed

    南育子,中川敏法,海渕覚,内田薫,岸川明日香,堀場大生,大貫宏一郎,清水邦義

    九州栄養福祉大学研究紀要   12   287 - 290   2015.8

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  • 睡眠誘導効果をもつ(-)-酢酸ボルニルの睡眠促進効果ならびに肌質改善効果 Reviewed

    清水邦義、松本清、大貫宏一郎

    コスメトロジー研究振興財団 研究業績 中間報告   197 - 235   2015.8

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  • Antiplatelet and Anticoagulant Activities of Angelica shikokiana Extract and its Isolated Compounds Reviewed International journal

    A. Mira, W, Alkhiary, Shimizu, K

    Wood Research Journal   6 ( 1 )   2015.7

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    DOI: doi: 10.1177/1076029615595879

  • Structure-Activity Relationship and Inhibition Pattern of Reishi-derived (Ganoderma lingzhi) Triterpenoids against Angiotensin-Converting Enzyme Reviewed International journal

    Shimizu, K, T. H. Bang

    Phytochemistry Letters   12   243 - 247   2015.6

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    DOI: doi:10.1016/j.phytol.2015.04.021

  • Structure-activity relationship and inhibition pattern of reishi-derived (Ganoderma lingzhi) triterpenoids against angiotensin-converting enzyme Reviewed

    Tran Hai-Bang, Kuniyoshi Shimizu

    Phytochemistry Letters   12   243 - 247   2015.6

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    DOI: 10.1016/j.phytol.2015.04.021

  • Multiple biological effects of olive oil by-products such as leaves, stems, flowers, olive milled waste, fruit pulp, and seeds of the olive plant on skin. Reviewed International journal

    A. Ashour, Q. Zhu, M. Yasuda, H. Ishikawa, Shimizu K

    Phytotherapy Research   26 ( 9 )   721 - 725   2015.6

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    DOI: DOI: 10.1002/ptr.5326

  • Determination of Seed Soundness in Conifers Cryptomeria japonica and Chamaecyparis obtusa Using Narrow-Multiband Spectral Imaging in the Short-Wavelength Infrared Range Reviewed International journal

    O. Matsuda, M. Hara, K. Yazaki, T. Nakagawa, Shimizu K, A. Uemura, H. Utsugi

    PLOS ONE   10 ( 6 )   2015.6

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    DOI: e0128358

  • Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design Invited Reviewed International journal

    Q. Zhu, T. H. Bang, K. Ohnuki, T. Sawai, K. Sawai, Shimizu K

    Scientific Reports   13194   2015.6

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    DOI: DOI: 10.1038/srep13194.

  • A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica) Reviewed

    Hui Tan, Ahmed Ashour, Yoshinori Katakura, Kuniyoshi Shimizu

    Phytomedicine   22 ( 4 )   498 - 503   2015.4

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    DOI: 10.1016/j.phymed.2015.03.002

  • In vitro bioactivities and phytochemical profile of various parts of the strawberry (Fragaria×ananassa var. Amaou)

    13 ( 1 )   38 - 49   2015.3

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  • The inhibitory activity of aldose reductase in vitro by constituents of Garcinia mangostana Linn.

    S. Fatmawat, T. Ersama, Shimizu, K.

    Phytomedicine   22 ( 1 )   49 - 51   2015.2

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  • In Vitro Neuroprotective Activities of Compounds from Angelica shikokiana Makino

    A. Mira, S. Yamashita, Y. Katakura, Shimizu, K.

    Molecules   20 ( 3 )   4813 - 4832   2015.2

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    DOI: 10.3390/molecules20034813

  • Anti-proliferative Activity of Some Oleanolic acid derivatives with Potent TopoisomeraseInhibitory Activity on B16 Melanoma Cells Invited Reviewed International journal

    Ahmed Ashour, Ryuichiro Kondo, Shimizu K

    Wood Research Journal   2015.1

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  • Determination of antioxidant and anti-melanogenesis activities of Indonesian Lai, Durio kutejensis [Bombacaceae (Hassk) Becc] fruit extract Reviewed International journal

    Enos Tangke Arung, Wiwin Suwinarti, Medi Hendra, Supomo, Irawan Wijaya Kusuma, Dwi Caesarina Nanda Puteri, Huseyin Avni Eroglu, Yongung Kim, @Kuniyoshi Shimizu, Hiroya Ishikawa

    Tropical Journal of Pharmaceutical Research   14 ( 1 )   41 - 46   2015.1

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  • Effect of chemical factors on integrated fungal fermentation of sugarcane bagasse for ethanol production by a white-rot fungus, Phlebia sp. MG-60 Reviewed International journal

    L. D. Khuong, R. Kon@do, R. D. Leon, T. K. Anh, @K. Shimizu, I. Kamei

    Bioresource Technology   30 - 40   2014.10

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    DOI: https://doi.org/10.1016/j.biortech.2014.05.064

  • Potent Angiotensin-Converting Enzyme Inhibitory Tripeptides identified by a Computer-based Approach

    T. H. Bang, Shimizu, K.

    Journal of Molecular Graphics and Modeling   53   206 - 211   2014.9

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  • Lipoxygenase inhibitory activity of alkyl protocatechuates

    Ha, T.J., Shimizu, K., Kubo, I.

    Food Chemistry   159 ( 15 )   471 - 476   2014.9

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  • 20(S)-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng

    Shimizu, K., S. Fatmawati, H. Yu, C. Zhang, F. Jin

    Bioorganic & Medicinal Chemistry Letters   24 ( 18 )   4407 - 4409   2014.9

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    DOI: 10.1016/j.bmcl.2014.08.009

  • Hypotensive effects of Reishi (Ganoderma lingzhi)’s auto-digested extract and its potent peptides for Angiotensin-Converting Enzyme inhibition

    19   13473 - 13485   2014.8

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    DOI: doi:10.3390/molecules190913473

  • Hypotensive effects and angiotensin-converting enzyme inhibitory peptides of reishi (Ganoderma lingzhi) auto-digested extract Reviewed International journal

    @Hai-Bang Tran, @Atsushi Yamamoto, @Sayaka Matsumoto, Hisatomi Ito, Kentaro Igami, Toshitsugu Miyazaki, @Ryuichiro Kondo,@Kuniyoshi Shimizu

    Molecules   19 ( 9 )   13473 - 13485   2014.8

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  • Biological activities and phytochemical profiles of extracts from different parts of bamboo (Phyllostachys pubescens)

    Molecules 2014, 19(6), 8238-8260   2014.6

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    DOI: 10.3390/molecules19068238

  • Production of citric acid from corncobs with its biological evaluation

    Ashour, A., EI-Sharkawy, S., Amer, M., Marzouk, A., Kishikawa, A., Ohzono, M., Kondo, R., Shimizu, K.

    Journal of Cosmetics, Dermatological Sciences and Applications   4 ( 3 )   141 - 149   2014.6

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  • Biodegradation of heptachlor-contaminated soil by white-rot fungal inocula

    Purnomo, A.S., Putri, E.M.M., Nawfa, R., Putra, S.R., Shimizu, K., Kondo, R.

    Environmental Science and Pollution Research   2014.5

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  • Bioethanol production from alkaline-pretreated sugarcane bagasse by consolidated bioprocessing using Phlebia sp. MG-60

    L. D. Khuong, R. Kondo, R. D. Leon, T. K. Anh, K. Shimizu, I. Kamei

    International Biodeterioration & Biodegradation   88 ( 3 )   62 - 68   2014.3

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  • The Inhibitory Effect of Loquat Leaves (Eriobotrya japonica) on Ovariectomy-induced Bone Loss and Osteoclast Differentiation Reviewed International journal

    T. Hui, S. Furuta, T. Nagata, K. Ohnuki, T. Akasaka, B. Shirouchi, M. Sato, R. Kondo, K. Shimizu

    Journal of Agricultural and Food Chemistry   62 ( 4 )   836 - 41   2014.1

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    DOI: doi: 10.1021/jf402735u

  • かすかな香りの効用 : 香りの定性定量分析および生理心理評価 Scent aroma with great potential : Function evaluation by qualitative and quantitative analysis and physiological and psychological assessment Reviewed

    松本 清、大貫 宏一郎、清水 邦義

    コスメトロジー研究報告   72 ( 5 )   395 - 398   2014.1

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  • Inhibitory Effects of the Leaves of Loquat (Eriobotrya japonica) on Bone Mineral Density Loss in Ovariectomized Mice and Osteoclast Differentiation Reviewed International journal

    Tan, H., Furuta, S., Nagata, T., Ohnuki, K., Akasaka, T., Shirouchi, B., Sato, M., Kondo, R., @Shimizu, K.

    Journal of Agricultural and Food Chemistry   62 ( (4) )   836 - 841   2014.1

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  • Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources Reviewed International journal

    Hai Bang, T., Suhara, H., Doi, K., Ishikawa, H., Fukami, K., Parajuli, G.P., Katakura, Y., Yamashita, S., Watanabe, K., Adhikari, M.K., Manandhar, H.K., Kondo, R., @Shimizu, K.

    Evidence-based Complementary and Alternative Medicine   2014.1

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    DOI: http://dx.doi.org/10.1155/2014/195305

  • Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs. International journal

    A. Ashour, S. El-Sharkawy, M. Amer, B. F. Abdel, Y. Katakura, T. Miyamoto, N. Toyota, T. H. Bang, R. Kondo, K. Shimizu

    Bioorg Med Chem.   22 ( 1 )   211 - 20   2014.1

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    DOI: doi: 10.1016/j.bmc.2013.11.034.

  • Effects of isolated compound from Sonneratia caseolaris leaf : a validation of traditional utilization by melanin biosynthesis and antioxidant assays

    E. T. Arung, H. Kuspradini, I. W. Kusuma, T. H. Bang, S. Yamashita, Y. Katakura, K. Shimizu

    submitted   2013.12

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  • Structure-activity relationships of lanostane-type triterpenoids from Ganoderma lingzhi as α-glucosidase inhibitors Reviewed International journal

    23 ( 21 )   5900 - 5903   2013.11

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    DOI: 10.1016/j.bmcl.2013.08.084

  • Corncobs as a potential source of functional chemicals.

    A. Ashour, M. Amer, A. Marzouk, K. Shimizu, R. Kondo, S. El-Sharkawy

    Molecules   18 ( 11 )   13823 - 13830   2013.11

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    DOI: doi:10.3390/molecules181113823

  • Hypotensive effects of Reishi (Ganoderma lingzhi)’s auto-digested extract and its potent peptides for Angiotensin-Converting Enzyme inhibition.

    2013.9

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  • Wild Mushroom in Nepal: Some potential Candidates as Antioxidant and ACE Inhibition Sources Reviewed International journal

    T. H. Bang, H. Suhara, K. Doi, H. Ishikawa, K. Fukami, G. P. Parajuli, Y. Katakura, S. Yamashita, K. Watanabe, M. K. Adhikari, H. K. Manandhar, R. Kondo, K. Shimizu

    Evidence-Based Complementary and Alternative Medicine   2014   2013.8

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    DOI: Volume 2014 (2014), Article ID 195305, 11 pages http://dx.doi.org/10.1155/2014/195305

  • A new lignan from corncobs, a potential source of functional chemicals Reviewed International journal

    A. Ashour, M. Amer, A. Marzouk, K. Shimizu, R. Kondo, S. El-Sharkawy

    2013.8

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  • Biotransformation of Khellin to Khellol by Aspergillus niger and the Evaluation of their Biological Activities. Reviewed International journal

    A. Ashour, S. El-Sharkawy, M. Amer, F.A. Bar, A. Mera, T. Nagata, R. Kondo, K. Shimizu

    The Open Bioactive Compounds Journal   4   1 - 3   2013.8

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  • Comparative Biological Study of Roots, Stems, Leaves, and Seeds of Angelica shikokiana Makino Reviewed International journal

    A. Mira, A. Tanaka, Y. Tateyama, R. Kondo, K. Shimizu

    J Ethnopharmacol   148   980 - 987   2013.8

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  • A protocol for isolation of target proteins of natural compound International journal

    J. Liu, K. Shimizu, A. Tanaka, W. Shinobu, K. Ohnuki, T. Nakamura, R. Kondo

    Protocol Exchange   2013.5

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    DOI: doi:10.1038/protex.2013.051

  • Antibacterial compounds from shoot skins of moso bamboo (Phyllostachys pubescens) Reviewed International journal

    K. Shimizu

    Journal of Wood Science   59 ( 2 )   2013.4

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    DOI: 10.1007/s10086-012-1310-6

  • Anti-salmonella agents from the Brazilian medicinal plant tanacetum balsamita and their applications Reviewed International journal

    Kubo, I., Fujita, K.-I., @Shimizu, K.

    Natural Antioxidants and Biocides from Wild Medicinal Plants   15   239 - 253   2013.4

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  • Melanin Biosynthesis Inhibitory Activity of Compounds Isolated from unused parts of Ammi visinaga

    A. Ashour, S. El-Sharkawy, M. Amer, F. A.l Bar, R. Kondo, K. Shimizu

    Journal of Cosmetics, Dermatological Sciences and Applications   3   40 - 43   2013.3

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  • ベチバー根の揮発成分のビジランス低下抑制効果 Reviewed

    清水邦義、深川未央、松原恵理、松本清、山本篤、石川洋哉、北村真吾、栫ちか子、畑山知子、永野純、岡本剛、大貫宏一郎

    14 ( 4 )   66 - 75   2013.2

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  • トマトの各部位のリパーゼ活性に及ぼす影響 Reviewed

    宮崎明日香, 室井由起子, 永田敏郎, 大貫宏一郎, 清水邦義

    九州栄養福祉大学研究紀要   10   389 - 392   2013.1

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  • ベチバー根の揮発成分のビジランス低下抑制効果 The inhibitory effect of the volatile emitted from the root of Vetiveria zizanioides on the decrement of attention in the long-term task in human Reviewed

    清水 邦義、深川 未央、松原 恵理

    14 ( 4 )   366 - 375   2013.1

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  • 成熟トマト・未成熟トマトの機能性評価 Reviewed International journal

    室井由起子, 宮崎明日香, 永田敏郎, 大貫宏一郎, 清水邦義

    九州栄養福祉大学研究紀要   10   369 - 374   2013.1

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  • Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms Reviewed International journal

    J. Liu, K. Shimizu, A. Tanaka, W. Shinobu, K. Ohnuki, T. Nakamura, R. Kondo.

    Sci. Rep. 2, 905   2012.11

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  • An ester of 4-methoxy cynnamic acid isolated from Xylocarpus moluccencis (Lamk) M. Roem (Meliaceae) Reviewed International journal

    Tukiran, S. S. Cahyasari, K. Shimizu

    Indonesian Journal of chemistry   12 ( 2 )   2012.7

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  • Volatiles emitted from the roots of Vetiveria zizanioides suppress the decline in attention during a visual display terminal task Reviewed International journal

    E. Matsubara, K. Shimizu, M. Fukagawa, Y. Ishizi, C. Kakoi, T. Hatayama, J. Nagano, T. Okamoto, K. Ohnuki, R. Kondo

    Biomedical Research   35 ( 5 )   2012.7

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  • Validation of Eupatorium triplinerve Vahl leaves, a skin care herbal from East Kalimantan in melanin biosynthesis assay Reviewed International journal

    E. T. Arung, H. Kuspradini I. W. Kusuma, K. Shimizu, R. Kondo

    Journal of Acupuncture and Meridian Studies   5 ( 2 )   2012.7

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  • The inhibitory effects of representative chalcones contained in Angelica keiskei on melanin biosynthesis in B16 melanoma cells Reviewed International journal

    E. T. Arung, S. Furuta, K. Sugamoto, K. Shimizu, H. Ishikawa, Y. Matsushita, R. Kondo

    Natural Products Communications   7 ( 8 )   2012.7

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  • Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii Reviewed International journal

    S. Yokoyama, T. H. Bang, K. Shimizu, R. Kondo

    Natural Products Communications   7 ( 9 )   2012.7

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  • The melanin biosynthesis stimulating compounds isolated from the fruiting bodies of Pleurotus citrinopileatus Reviewed International journal

    T.X. Meng, C.-F. Zhang, T. Miyamoto, H. Ishikawa, K. Shimizu, S Ohga, R. Kondo

    Journal of Cosmetics, Dermatological Sciences and Applications   2   2012.7

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  • Antioxidantive compounds from leaves of Tahongai (Klienhovia hospita) Reviewed International journal

    E. T. Arung, I. W. Kusuma, Y.-U. Kim, K. Shimizu, R. Kondo

    Journal of Wood Science,58(1)77-80   58 ( 1 )   2012.4

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  • A glucosylceramide with antimicrobial activity from the edible mushroom Pleurotus citrinopileatus Reviewed International journal

    T. X. Meng, H. Ishikawa, K. Shimizu, S. Ohga, R. Kondo

    Journal of Wood Science   58 ( 1 )   2012.2

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  • Quantitative determination of the representative triterpenoids in the extracts of Ganoderma lucidum with different growth stages using high-performance liquid chromatography for evaluation of their 5α-reductase inhibitory properties Reviewed International journal

    133   2012.2

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  • Maniçoba, a quercetin rich amazonian dish: Antioxidative prospects Reviewed International journal

    ( 26 )   129 - 154   2012.1

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    A large quantity of quercetin was characterized from a local dish, known as maniçoba in Pará, Brazil. The fresh leaf of Manihot esculenta Crantz (Euphorbiaceae), a principal ingredient for maniçoba, was found to contain a large amount of rutin or quercetin 3-O-rutinoside which was completely hydrolyzed to quercetin during cooking processes. Antioxidant activity of quercetin and its microfloral metabolites was examined. Quercetin inhibited the oxidation of linoleic acid catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, Type 1) with an IC50of 4.5 μM, while rutin did not inhibit this oxidation up to 200 μM. The progress curves for the enzyme reaction indicate that quercetin shows slow binding kinetics. In the pseudoperoxidase activity, hydroperoxides slowly oxidize quercetin to a rather stable intermediate,
    2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone. A microfloral metabolite of quercetin and rutin after ingestion, 3,4-dihydroxyphenylacetic acid, also scavenged superoxide anion generated by xanthine oxidase and inhibited uric acid formation. The antioxidant activity observed with the methanol extract of maniçoba is due mainly to multifunctional quercetin's response.

  • 樹木由来のかすかな香り : 生理・心理応答解析からみえること (特集 木の香りが生理に及ぼす影響) Scent aroma derived from woods : the consideration based on Reviewed

    清水 邦義、松原 恵里、福田 竜大

    アロマリサーチ   31 ( 9 )   202 - 208   2012.1

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  • Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors Reviewed International journal

    S. Fatmawati, K. Shimizu, R. Kondo

    Bioorganic & Medicinal Chemistry Letters, 21(24), 7295-7297   2011.12

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  • Combination effect of miconazole with polygodial against Candida albicans Reviewed International journal

    I. Kubo, S. H. Lee, K. Shimizu

    Open Journal of Medical Microbiology, 1, 7-11   2011.12

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  • Antibacterial activity of moso bamboo shoot skin (Phyllostachys pubescens) against Staphylococcus aureus. Reviewed International journal

    A. Tanaka, H. J. Kim, S. Oda, K. Shimizu, R. Kondo

    Journal of Wood Science   57 ( 6 )   542 - 544   2011.10

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  • Antioxidant activity of compounds from wood of Artocarpus heterophyllus Reviewed International journal

    E. T. Arung, K. Shimizu

    Indonesian Journal of Pharmaceutical Sciences   9 ( 2 )   72 - 77   2011.9

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  • Artocarpus Plants as a Potential Source of Skin Whitening Agents Reviewed International journal

    Arung, E.T.,@Shimizu, K., Kondo, R.

    Natural Product Communications   6 ( 9 )   1397 - 1402   2011.8

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    DOI: https://doi.org/10.1177/1934578X1100600943

  • Evaluation of biological activities of extracts from the fruiting body of Pleurotus citrinopileatus for skin cosmetics Reviewed International journal

    T.X. Meng, S. Furuta, S. Fukamizu, R. Yamamoto, H. Ishikawa, E.T. Arung, K. Shimizu, S. Ohga, R. Kondo

    Journal of Wood Science   57 ( 5 )   452 - 458   2011.5

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  • Melanin Biosynthesis Inhibitory and Antioxidant Activities of Quercetin-3'-O-b-D-glucoside Isolated from Allium cepa

    E. T. Arung, S. Furuta, H. Ishikawa, H. Tanaka, K. Shimizu, R. Kondo

    66 ( 5-6 )   209 - 214   2011.4

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  • Ganoderol B: a potent alpha-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum Reviewed International journal

    S. Fatmawati, K. Shimizu, R. Kondo

    Phytomedicine   18 ( 12 )   1053 - 1055   2011.2

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  • (-)-酢酸ボルニルの多機能性~“森の香り”(-)-酢酸ボルニルが視覚作業後の覚醒状態や緊張緩和に及ぼす効果~ Reviewed

    松原恵理、深川未央、岡本剛、大貫宏一郎、清水邦義、近藤隆一郎

    45 ( 12 )   101 - 108   2011.2

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  • Volatiles emitted from the leaves of Laurus nobilis L. improve vigilance performance in visual discrimination task Reviewed International journal

    E. Matsubara, M. Fukagawa, T. Okamoto, A. Fukuda, C. Hayashi, K. Ohnuki, K. Shimizu, R. Kondo

    Biomedical Research   32 ( 1 )   19 - 28   2011.2

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  • The essential oil of Abies sibirica (Pinaceae) reduces arousal levels after visual display terminal work

    E. Matsubara, M. Fukagawa, T. Okamoto, K. Ohnuki, K. Shimizu, R. Kondo

    Flavour and Fragrance Journal   26 ( 3 )   204 - 210   2011.2

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  • (-)-Bornyl acetate induces autonomic relaxation and reduces arousal level after visual display terminal work without any influences of task performance in low-dose condition Reviewed International journal

    E. Matsubara, M. Fukagawa, T. Okamoto, K. Ohnuki, K. Shimizu, R. Kondo

    Biomedical Research   32 ( 2 )   151 - 157   2011.2

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  • Inhibitory components from the buds of clove (Syzygium aromaticum) on melanin formation in B16 melanoma cells Reviewed International journal

    E. T. Arung, E. Matsubara, I. W. Kusuma, E. Sukaton, K. Shimizu, R. Kondo

    Fitoterapia   82 ( 2 )   2011.2

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  • Tyrosinase inhibitory effect of quercetin 4'-O-b-glucopyranoside from dried skin of Red Onion (Allium cepa)

    E. T. Arung, K. Shimizu, I. W. Kusuma, R. Kondo.

    Natural Product Research   25 ( 3 )   2011.2

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  • Reduction of Ammonia Emission during Composting of Poultry Manure by Covering with Cedar Bark Reviewed International journal

    Koyama, F., Koyama, F.,@Shimizu, K., Matsubara, E., Yoshida, E., Kondo, R.

    Mokuzai Gakkaishi/Journal of the Japan Wood Research Society   57 ( 6 )   370 - 376   2011.1

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  • モミ精油の多機能性~モミ精油は視覚作業後の覚醒状態を低下させる~ Reviewed

    松原恵理、深川未央、岡本剛、大貫宏一郎、清水邦義、近藤隆一郎

    46 ( 12 )   101 - 108   2011.1

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  • 月桂樹の多機能性~月桂樹葉揮発成分が注意力維持に及ぼす効果~ Reviewed

    松原恵理、深川未央、岡本剛、福田淳子、林ちか子、大貫宏一郎、清水邦義、近藤隆一郎

    370 - 379   2010.12

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  • Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum Reviewed International journal

    S. Fatmawati, K. Shimizu, R. Kondo

    Planta Med   76 ( 15 )   1691 - 1693   2010.11

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  • Cytotoxic effect of artocarpin on T47D cells Reviewed International journal

    E. T. Arung, B. D. Wicaksono, Y. A. Handoko, I. W. Kusuma, K. Shimizu, D. Yulia, F. Sandra

    J. Nat. Med.   64 ( 4 )   2010.10

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  • ヤマブシタケの多機能性~中年女性におけるヤマブシタケの不定愁訴改善効果の検証~ Reviewed

    清水邦義、長野真弓、林ちか子、古田祥子、近藤隆一郎、佐藤大吾、北川勝幸、大貫宏一郎

    11 ( 3 )   276 - 283   2010.10

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  • Ganoderic acid Df, a new triterpenoid with aldose reductase activity from the fruiting body of Ganoderma lucidum Reviewed International journal

    S. Fatmawati, K. Shimizu, R. Kondo

    Fitoterapia.   81 ( 8 )   1033 - 1036   2010.9

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  • Anti-melanogenesis properties of quercetin- and its derivative-rich extract from Allium cepa Reviewed International journal

    E. T. Arung, S. Furuta, H. Ishikawa, I. W. Kusuma, K. Shimizu, R. Kondo

    Food Chemistry   124 ( 3 )   2010.9

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  • Stereospecificity of hydroxyl group at C-20 in antiproliferative action of ginsenoside Rh2 on prostate cancer cells Reviewed International journal

    Fitoterapia.   81 ( 7 )   902 - 905   2010.9

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  • The effects of ganoderma alcohols isolated from Ganoderma lucidum on the androgen receptor binding and the growth of LNCaP cells Reviewed International journal

    J. Liu, K. Shimizu, R. Kondo

    Fitoterapia.   81 ( 8 )   1067 - 1072   2010.9

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  • Inhibition mode of soybean lipoxygenase-1 by quercetin

    T.J. Ha, K. Shimizu, T. Ogura, I. Kubo

    Chem. Biodiversity   7 ( 8 )   1893 - 1903   2010.8

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  • 天然素材の多機能性(2)パンノキ属樹木抽出物の多機能性--4位置換レゾルシノール構造を有するイソプレニル置換ポリフェノールの多機能性生理活性発現機構 Reviewed

    清水 邦義 , Arung Enos Tangke , 近藤 隆一郎

    11 ( 2 )   176 - 183   2010.8

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  • Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake Reviewed International journal

    M. Nagano, K. Shimizu, R. Kondo, C. Hayashi, D. Sato, K. Kitagawa, K. Ohnuki

    Biomedical Research   31 ( 4 )   2010.8

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  • Antidermatophyte and antimelanogenesis compound from Eleutherine americana growing in Indonesia

    I. W. Kusuma, E. T. Arung, E. Rosamah, S. Purwatiningsih, H. Kuspradini, Syafrizal, J. Astuti, Y-U, Kim, K. Shimizu

    J. Nat. Med.   64 ( 2 )   223 - 226   2010.7

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  • 霊芝の多機能性 ~トリテルペノイドの抗男性ホルモン活性ならびに破骨細胞分化抑制活性に着目して~ Reviewed International journal

    劉潔、清水邦義、近藤隆一郎

    11 ( 1 )   70 - 75   2010.7

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  • パンノキ属樹木抽出物の多機能性~4位置換レゾルシノール構造を有するイソプレニル置換ポリフェノールの多機能性生理活性発現機構~ Invited Reviewed International journal

    清水邦義、エノスタンケアルング、近藤隆一郎

    11 ( 2 )   176 - 183   2010.7

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  • 3-Prenyl luteolin, a new prenylated flavone with melanin biosynthesis inhibitory activity from wood of Artocarpus heterophyllus

    E. T. Arung, K. Shimizu, H. Tanaka, R. Kondo

    Fitoterapia.   81 ( 6 )   2010.6

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  • Screening of extracts of Japanese medicinal plants for HMG-CoA reductase inhibition Reviewed International journal

    S. Yokoyama, S. Takeno, T. Nagata, K. Shimizu, R. Kondo

    Bulletin of the Kagoshima University Forest   37   2010.5

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  • Melanin biosynthesis inhibitors from wood of Artocarpus heterophyllus: The effect of isoprenoid substituent of flavone with 4-substituted resorcinol moiety at B ring Reviewed International journal

    E. T. Arung, K. Shimizu, H. Tanaka, R. Kondo

    Lett. Drug Des. Discovery   7 ( 8 )   2010.5

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  • Lipoxygenase inhibitory activity of 6-pentqadecanylsalicylic acid without prooxidant effect Reviewed International journal

    I. Kubo, T.J. Ha, K. Shimizu

    Natural Product Communications   5 ( 1 )   2010.5

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  • Ganoderic acids from Ganoderma lucidum. Inhibitory activity of osteoclastic differentiation and structural criteria Reviewed International journal

    J. Liu, J. Shiono, K. Shimizu, R. Kondo

    Planta Med.   76   2010.5

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  • Isoprenoid-substituted flavonoids from wood of Artocarpus heterophyllus on B16 melanoma cell -Cytotoxicity and structural criteria- Reviewed International journal

    E. T. Arung, K. Yoshikawa, K. Shimizu, R. Kondo

    Fitoterapia   81   2010.4

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  • Antidermatophyte and antimelanogenesis compound from Eleutherine americana grown in Indonesia Reviewed International journal

    Kusuma, I.W., Arung, E.T., Rosamah, E., Purwatiningsih, S., Kuspradini, H., Syafrizal, Astuti, J., Kim, Y.-U.,@Shimizu, K.

    Open Bioactive Compounds Journal   64 ( 2 )   223 - 226   2010.4

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  • Isoprenoid-substituted flavonoids from wood of Artocarpus heterophyllus on B16 melanoma cells: Cytotoxicity and structural criteria Reviewed International journal

    Arung, E.T., Yoshikawa, K., @Shimizu, K., Kondo, R.

    Fitoterapia   81 ( 2 )   120 - 123   2010.3

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  • Multifunctional antioxidant activities of alkyl gallates Reviewed International journal

    Kubo, I., Masuoka, N., Ha, T.J., @Shimizu, K., Nihei, K.

    Open Bioactive Compounds Journal   3   1 - 11   2010.1

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  • 天然素材の多機能性(1)霊芝の多機能性--トリテルペノイドの抗男性ホルモン活性ならびに破骨細胞分化抑制活性に着目して Reviewed

    劉 潔 , 清水 邦義 , 近藤 隆一郎

    11 ( 1 )   70 - 75   2010.1

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  • 天然素材の多機能性(3)ヤマブシタケの多機能性--中年女性におけるヤマブシタケの不定愁訴改善効果の検証 Reviewed

    清水 邦義 , 長野 真弓 , 林 ちか子

    11 ( 3 )   276 - 283   2010.1

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  • Ganoderic acids from ganoderma lucidum: Inhibitory activity of osteoclastic differentiation and structural criteria Reviewed International journal

    Liu, J., Shiono, J., @Shimizu, K., Kondo, R.

    Planta Medica   76 ( 2 )   137 - 139   2010.1

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    DOI: 10.1055/s-0029-1186035

  • Evaluation of medicinal plants from Central Kalimantan for anti melanogenesis Reviewed International journal

    E. T. Arung, I. W. Kusuma, E. O. Christy, K. Shimizu, R. Kondo

    J. Nat. Med.   63   2009.12

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  • Evaluation of biological activities of extracts from 22 African tropical wood species Reviewed International journal

    Z. Huang, K. Hashida, R. Makino, F. Kawamura, K. Shimizu, R. Kondo, S. Ohara

    J. Wood Sci   55 ( 3 )   2009.5

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  • Antioxidant Activity and Cytotoxicity of the Traditional Indonesian Medicine Tahongai (Kleinhovia hospita L.) Extract Reviewed International journal

    E.T. Arung, I.W. Kusuma, S. Purwatiningsih, S.-S. Roh, C.H. Yang, S. Jeon, Y.-U. Kim, E. Sukaton, J. Susilo, Y. Astuti, B.D. Wicaksono, F. Sandra, K. Shimizu, R. Kondo

    JAMS Journal of Acupuncture and Meridian Studies   2 ( 4 )   2009.5

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  • Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor Reviewed International journal

    J. Liu, J. Shiono, K. Shimizu, A. Kukita, T. Kukita, R. Kondo

    Bioorg. Med. Chem. Lett.   19   2009.5

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  • 20(R)-Ginsenoside Rh2, not 20(S), is a selective osteoclastgenesis inhibitor without any cytotoxicity Reviewed International journal

    Bioorg. Med. Chem. Lett.   19   2009.5

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  • Methyl ganoderic acid DM: a selective potent osteoclastgenesis inhibitor Reviewed International journal

    J. Liu, J. Shiono, Y. Tsuji, K. Shimizu, R. Kondo

    The Open Bioactive Compounds Journal   2   2009.5

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  • Provenance variation in growth and wood properties of A. mangium and A. auriculiformis in Central Java, Indonesia : selecting potential hybrid parents for good performance Reviewed

    M. Hasegawa, R. Wakimoto, E. Yoshida, K. Shimizu, R. Kondo, A. Widyatmoko, A. Nirsatmanto, S. Shiraishi

    Bull. Kyushu Univ. For.   90   2009.5

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  • Estrogen-like activity of ethanol extract of Ganoderma lucidum Reviewed International journal

    K. Shimizu, I. Miyamoto, J. Liu, F. Konishi, S. Kumamoto, R. Kondo

    J. Wood Sci.   55   2009.4

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  • Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum Reviewed International journal

    I. Miyamoto, J. Liu, K. Shimizu, A. Kukita, T. Kukita, M. Sato, R. Kondo

    Eur. J. Pharmacol.   602 ( 1 )   2009.4

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  • Anti-androgenic activity of fatty acids

    J. Liu, K. Shimizu, R. Kondo

    Chemistry&Biodiversity   6 ( 4 )   503 - 512   2009.4

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  • Anti-androgen effects of extracts and compounds from Ganoderma lucidum Reviewed International journal

    J. Liu, S. Tamura, K. Kurashiki, K. Shimizu, K. Noda, F. Konishi, S. Kumamoto, R. Kondo

    Chem. Biodiversity   6   2009.4

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  • The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum Reviewed International journal

    S. Fatmawatia, K. Kurashiki, S. Takeno, Y. Kim, K. Shimizu, M. Sato, K. Imaizumi, K. Takahashi, S. Kamiya, S. Kaneko, R. Kondo

    Phytotherapy Research   23   2009.3

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  • 粗しょう症, 前立腺肥大症への朗報となるマンネンタケ Reviewed International journal

    近藤 隆一郎 , 劉 潔 , 清水 邦義

    31 ( 9 )   35 - 39   2008.9

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  • Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms Reviewed International journal

    Noguchi, M., Kakuma, T., Tomiyasu, K., Yamada, A., Itoh, K., Konishi, F., Kumamoto, S., @Shimizu, K., Kondo, R., Matsuoka, K.

    Asian Journal of Andrology   10 ( 5 )   777 - 785   2008.8

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    DOI: https://doi.org/10.1111/j.1745-7262.2008.00361.x

  • ラットへの Ganoderma lucidum (レイシ)抽出物12週間経口投与による毒性試験 Invited Reviewed International journal

    小西 史子 , 隈本 正一郎 , 野田 潔 , 隈本 能光 , 中嶋 裕也 , 清水 邦義 , 近藤 隆一郎

    応用薬理   75 ( 1 )   7 - 12   2008.8

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  • レイシエキス含有食品の下部尿路排尿障害を有する中高年男性に対する過剰摂取時の安全性試験 Reviewed

    野口 正典 , 角間 辰之 , 富安 克郎 , 名切 信 , 山田 亮 , 伊東 恭悟 , 小西 史子 , 中嶋 裕也 , 隈本 正一郎 , 清水 邦義 , 近藤 隆一郎 , 松岡 啓

    応用薬理   75 ( 1 )   13 - 17   2008.8

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  • Effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: A double-blind, placebo-controlled randomized and dose-ranging study Reviewed International journal

    Masanori Noguchi, Tatsuyuki Kakuma, Katsuro Tomiyasu, Yoshiko Kurita, Hiroko Kukihara, Fumiko Konishi, Shoichiro Kumamoto,@Kuniyoshi Shimizu, Ryuichiro Kondo , Kei Matsuoka

    Asian Journal of Andrology   10 ( 4 )   651 - 658   2008.7

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  • An extract of ganoderma lucidum in men with lower urinary tract symptoms: A double-blind, placebo-controlled randomized and dose-ranging study Reviewed International journal

    M. Noguchi, K. Tomiyasu, M, Nakiri, K. Matsuoka, T. Kakuma, F. Konishi, S. Kumamoto, K. Shimizu, R. Kondo

    Nishinihon Journal of Urology   70 ( 9 )   2008.4

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  • Artocarpin, a promising compound as whitening agent and skin cancer Reviewed International journal

    E. T. Arung, S. Muladi, E. Sukaton, K. Shimizu, R. Kondo

    Journal of Wood Science and Technology   6   2008.4

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  • Essential Oil of Lavender Inhibited the Decrement of Attention in the Long-term Task in Human Reviewed International journal

    K. Shimizu, M. Gyokusen, S. Kitamura,T. Kawabe, T. Kozaki, K. Ishibashi, R. Izumi, W. Mizunoya, K. Ohnuki, R. Kondo

    Bioscience, Biotechnology, and Biochemistry   72 ( 7 )   2008.4

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  • ビジランス(持続的注意力)に着目した香りの機能性の評価

    清水 邦義, 玉泉 真弓, 北村 真吾, 河邉 隆寛, 小崎 智照, 石橋 圭太, 泉 龍介, 水野谷 航, 大貫 宏一郎, 近藤 隆一郎

    2008.3

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  • Steroid 5α-reductase inhibitory activity of condensed tannins from woody plants Reviewed International journal

    54 ( 1 )   2008.3

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  • A randamized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms Reviewed International journal

    M. Noguchi, T. Kakuma, K. Tomiyasu, A. Yamada, K. Itoh, F. Konishi, S. Kumamoto, K. Shimizu, R. Kondo, K. Matsuoka

    Asian Journal of Andrology   10 ( 5 )   2008.3

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  • The effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: A double-blaind, placebo-controlled randomized and dose-ranging study Reviewed International journal

    M. Noguchi, T. Kakuma, K. Tomiyasu, Y. Kurita, H. Kukihara, F. Konishi, S. Kumamoto, K. Shimizu, R. Kondo, K. Matsuoka

    Asian Journal of Andrology   10 ( 4 )   2008.3

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    Language:English   Publishing type:Research paper (scientific journal)  

  • 自然由来揮発成分のLOHAS指向豊かさ因子としての検証

    清水邦義, 玉泉真弓, 高田奈津美, 村上千尋, 河邉隆寛, 小崎智照, 石橋圭太, 泉 龍介, 水野谷 航, 大貫宏一郎, 近藤 隆一郎

    第5回「循環型住空間システムの構築」フォーラム-4年間の研究成果と最終年度に向けて-   2008.1

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  • 高齢化社会に対応した霊芝の機能性--骨粗鬆症予防・改善効果 Reviewed International journal

    清水 邦義 , 宮本 以智子 , 塩野 順

    グリーンスピリッツ   3 ( 4 )   3 - 10   2008.1

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  • 高齢性社会に対応した霊芝の機能性~前立腺肥大症改善・予防効果

    劉潔, 清水邦義, 近藤隆一郎

    2007.11

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  • Screening of extracts of Japanese woods for melanin biosynthesis inhibition Reviewed International journal

    K. Shimizu, S. Fukunaga, K. Yoshikawa, R. Kondo

    J. Wood Sci.   53   2007.10

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  • Structure-activity relationship of prenyl-substituted polyphenols from Artocarpus heterophyllus as inhibitors of melanin biosynthesis in cultured melanoma cells Reviewed International journal

    Arung, E.T., @Shimizu, K., Kondo, R.

    Chemistry and Biodiversity   4 ( 9 )   2166 - 2171   2007.9

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    DOI: https://doi.org/10.1002/cbdv.200790173

  • Steroid 9a-hydroxylation during testosterone degradation by resting Rhodococcus equi Cells Reviewed International journal

    Y. Kim, J. Han, S. S. Lee, K. Shimizu, Y. Tsutsumi, R. Kondo

    Arch. Pharm. Chem. Life Sci..   340   2007.7

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  • Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum Reviewed International journal

    J. Liu, K. Shimizu, F. Konishi, K. Noda, S. Kumamoto, K. Kurashiki, R. Kondo

    Food Chem.   100   2007.6

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  • 高齢化社会に対応した男性ホルモン調節機能を有するキノコ(霊芝)の開発

    清水 邦義

    福岡商工会議所ニュース   2007.5

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  • The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum Reviewed International journal

    J. Liu, K. Shimizu, F. Konishi, S. Kumamoto, R. Kondo

    Bioorg. Med. Chem.   15 ( 14 )   2007.3

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  • Isoprenoid-substituted polyphenols from Artocarpus heterophyllus -Melanin biosynthesis inhibitory activity and structural criteria- Reviewed International journal

    Enos T. Arung, K. Shimizu, R. Kondo

    Chemistry & Biodiversity   4   2007.3

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  • Steroid 9a-hydroxylation during testosterone degradation by resting Rhodococcus equi Cells International journal

    Y. Kim, J. Han, S. S. Lee, K. Shimizu, Y. Tsutsumi, R. Kondo

    Arch. Pharm. Chem. Life Sci   2007.1

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  • Structure activity relationship for inhibition of 5α-reductase by triterpenoids isolated from Ganoderma lucidum Reviewed International journal

    14 ( 24 )   2006.12

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  • Briononic acid from the hexane extract of Sandoricum koetjape Merr. stem bark (Meliaceae) Reviewed International journal

    Tukiran, Saidah, Suyatno, Nurul Hidayati, K Shimizu

    Indo. J. Chem.   6 ( 3 )   2006.11

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  • マンネンタケ(Ganoderma lucidum)エタノール抽出物による骨粗鬆症予防効果 Reviewed International journal

    @清水 邦義, 宮本 以智子, 塩野 順, 佐藤 匡央, 久木田 明子, 久木田 敏夫, 近藤 隆一郎

    機能性食品と薬理栄養   4 ( 1 )   29 - 36   2006.11

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  • Hemsleyanoside F, an oligoresveratrol glucoside from the stem bark of Shorea parvistipulata F. Heim. Reviewed International journal

    Tukiran, K. Sakai, K. Shimizu, S.A. Achmad

    Bull. Soc. Nat. Prod. Chem. (Indonesia)   6   2006.11

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  • Antioxidant activity of anacardic acids Reviewed International journal

    Masuoka, N., @Shimizu, K., Kubo, I.

    Food Chemistry   99 ( 3 )   555 - 562   2006.8

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    DOI: https://doi.org/10.1016/j.foodchem.2005.08.023

  • Estrogen-like activity and prevention effect of bone loss in calcium deficient ovariectomized rats by the extract of Pleurotus eryngii. Reviewed International journal

    K. Shimizu, M. Yamanaka, M. Gyokusen, S. Kaneko, M. Tsutsui, J. Sato, I. Sato, M. Sato, R. Kondo

    Phytotherapy Research   20   2006.1

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  • 霊芝の前立腺肥大・骨粗鬆症改善効果 Reviewed

    清水邦義、劉潔、宮本以智子、近藤隆一郎

    食品・食品添加物研究誌   211 ( 2 )   124 - 133   2006.1

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  • Inhibitory effect of Artocarpanone from Artocarpus heterophyllus on melanin biosynthesis Reviewed International journal

    Enos T. Arung, K. Shimizu, R. Kondo

    Biol Pharm. Bull.   29   2006.1

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  • Inhibitory Effect of Isoprenoid-substituted Flavonoids Isolated from Artocarpus heterophyllus on Melanin Biosynthesis Reviewed International journal

    Enos T. Arung, K. Shimizu, R. Kondo

    Planta Med   72   2006.1

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  • 5a-reductase inhibitory effects of triterpenoids isolated from Ganoderma lucidum. Reviewed International journal

    J. Liu, K. Kurashiki, K. Shimizu, R. Kondo

    Biol. Pharm. Bull.   29   2006.1

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  • Ganoderic acid TR, a new lanostanoid with 5a-reductase inhibitory activity from the fruiting body of Ganodema lucidum. Reviewed International journal

    J. Liu, K. Shimizu, R. Kondo

    Natural Product Communications   1 ( 5 )   2006.1

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  • Oligostilbenoids from the stem bark of Shorea selanica Blume (Dipterocarpaceae) Reviewed International journal

    Tukiran, S.A. Achmad, E.H. Hakim, Y.M. Syah, L. Makmur, L.D. Juliawaty, K. Shimizu, and K. Sakai.

    Malaysian Journal of Science (MJS),   24 ( 1 )   2005.1

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  • Screening of Indonesian plants for tyrosinase inhibitory activity Reviewed International journal

    Enos T. Arung, Irawan W. Kusuma, Yetti M. Iskandar, S. Yasutake, K. Shimizu, R. Kondo

    J. Wood Sci..   51 ( 5 )   520 - 525   2005.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10086-004-0690-7

  • The effect of chlorophorin and its derivatives on melanin biosynthesis. Reviewed International journal

    Enos T. Arung, K. Yoshikawa., K. Shimizu, R. Kondo

    Holzforschung   59 ( 5 )   514 - 518   2005.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1515/HF.2005.085

  • The effect of strain, growth stage and cultivationg condition of Ganoderma lucidum on 5a-reductase inhibition Reviewed International journal

    J. Liu, R. Fujita, M. Sato, K. Shimizu, F. Konishi, K. Noda, S. Kumamoto, C. Ueda, H. Tajiri, S. Kaneko, Y. Suimi, R. Kondo

    J. Wood Sci   51 ( 2 )   189 - 192   2005.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10086-004-0645-z

  • Anti-androgenic activities of Ganoderma lucidum. Reviewed International journal

    R. Fujita, J. Liu, K. Shimizu, F. Konishi, K. Noda, S. Kumamoto, C. Ueda, H. Tajiri, S. Kaneko, Y. Suimi, R. Kondo

    J. Ethnopharmacol.   102 ( 1 )   107 - 112   2005.1

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    DOI: 10.1016/j.jep.2005.05.041

  • Oligostilbenoids from Shorea balangeran. Reviewed International journal

    Tukiran, S.A. Achmad, E.H. Hakim, L. Makmur, K. Sakai, K. Shimizu, and Y.M. Syah

    Biochemical systematic and Ecology (BSE),   33 ( 6 )   631 - 634   2005.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bse.2004.10.016

  • マンネンタケ抽出物の抗男性ホルモン効果 Reviewed International journal

    @劉 潔, @清水 邦義, 小西 史子, 野田 潔, 隈本 正一郎, 金子 周平, 水海 吉太郎, 近藤 隆一郎

    機能性食品と薬理栄養   2 ( 2 )   67 - 72   2004.11

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  • Resveratrol oligomers from the stem bark of Hopea bancana (Dipterocarpaceae) Reviewed International journal

    Tukiran, Sjamsul A. Achmad, Euis H. Hakim, Yana M. Syah, Lukman Makmur, Lia D. Juliawaty, K. Shimizu, K. Sakai

    Bull. Soc. Nat. Prod. Chem. (Indonesia)   4   2004.1

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  • Oxidation products of quercetin catalyzed by mushroom tyrosinase Reviewed International journal

    I kubo, K. Nihei,K. Shimizu

    Bioorg. Med. Chem.   12   2004.1

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  • Antibacterial activity of ent-kaurene diterpenoids from Rabdosia rosthornii. Reviewed International journal

    I. Kubo, Y Xu, K Shimizu

    Phytother Res.   18 ( 2 )   2004.1

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  • Arudonine, an allelopathic steroidal glycoalkaloid from the root bark of Solanum arundo Mattei Reviewed International journal

    K. Fukuhara, K. Shimizu, I. Kubo

    Phytochemistry   65 ( 9 )   2004.1

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  • Morphological features and dietary functional components in fruit bodies of two strains of Pholiota adiposa grown on artificial beds Reviewed International journal

    @Shimizu, K., Fujita, R., Kondo, R., Sakai, K., Kaneko, S.

    Journal of Wood Science   49 ( 2 )   193 - 196   2003.4

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  • entIsopimarane diterpenoids of the leaves from Rabdosia forrestii Reviewed International journal

    I. Kubo, K. Shimizu, Y.L. Xu

    Fitoterapia   74 ( 7-8 )   2003.1

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  • 4位置換レゾルシノール誘導体のメラニン生成抑制効果 Reviewed International journal

    清水 邦義 , 安武 政司 , 近藤 隆一郎

    コスメトロジー研究報告   11   16 - 22   2003.1

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  • Polyphenols from the heartwood of Cercidiphyllum japonicum and their effects on proliferation of mouse hair epithelial cells Reviewed International journal

    K. Towatari, K. Yoshida, N. Mori, K. Shimizu, R. Kondo, K. Sakai

    Planta Med.   68 ( 11 )   2002.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-2002-35657

  • Antioxidant activity of heartwood extracts of Papua New Guinean woods. Reviewed International journal

    K. Shimizu, R. Kondo, K. Sakai

    J. Wood. Sci.   48 ( 5 )   2002.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/BF00770708

  • The skin-lightening effects of artocarpin on UVB -induced pigmentation. Reviewed International journal

    K. Shimizu, R. Kondo, K. Sakai, N. Takeda, T. Nagahata

    Planta Med.   68 ( 1 )   2002.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-2002-20057

  • Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties. Reviewed International journal

    K. Shimizu, R. Kondo, K. Sakai, N. Takeda, T. Nagahata, T. Oniki

    Lipids   36 ( 12 )   2001.3

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    DOI: 10.1007/s11745-001-0847-9

  • A geranylated chalcone with 5α-reductase inhibitory properties from Artocarpus incisus. Reviewed International journal

    54 ( 8 )   2001.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0031-9422(00)00187-4

  • The 5α-reductase inhibitory components from heartwood of Artocarpus incisus: Structure-activity investigations Reviewed International journal

    @Kuniyoshi Shimizu, Masayuki Fukuda, Ryuichiro Kondo*, and, Kokki Sakai

    66 ( 1 )   16 - 19   2000.11

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  • 5α-Reductase inhibitory component from leaves of Artocarpus altilis Reviewed International journal

    @Kuniyoshi Shimizu, Ryuichiro KondoEmail author, Kokki Sakai, Supanida Buabarn and Uraiwan Dilokkunanant

    46 ( 5 )   385 - 389   2000.10

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  • The 5α-reductase inhibitory activity and hair regrowth effects of extract from Boehmeria nipononivea. Reviewed International journal

    64   2000.3

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  • The 5α-reductase inhibitiory components from heartwood of Artocarpus incisus: Structure-activity investigations. Reviewed International journal

    66 ( 1 )   2000.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-2000-11114

  • Inhibition of tyrosinase by flavonoids, stilbenes and related 4-substituted resorcinols: Structure-activity investigations. Reviewed International journal

    K. Shimizu, R. Kondo and K. Sakai

    Planta Med.   66 ( 1 )   2000.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-2000-11113

  • The 5α-reductase inhibitory component from leaves of Artocarpus altilis. Reviewed International journal

    46   2000.3

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  • The Inhibitory Components from Artocarpus incisus on Melanin Biosynthesis. Reviewed International journal

    K. Shimizu, R. Kondo, K. Sakai, S.-H. Lee, H. Sato

    Planta Med.   64 ( 5 )   1998.3

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    DOI: 10.1055/s-2006-957470

  • A Stilbene Derivative from Artocarpus incisus. Reviewed International journal

    K. Shimizu, R. Kondo, K. Sakai

    Phytochemistry   45 ( 6 )   1997.3

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    DOI: 10.1016/S0031-9422(97)00143-X

  • An Examination of the Anti-fungal Components in the Heartwood Extracts of Pterocarpus indicus. Reviewed International journal

    Mokuzai gakkaishi   41 ( 6 )   1995.3

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  • A new pimarane-type diterpene obtained by biotransformation inhibits human HCT-116 colorectal carcinoma through inhibition of LTA4H activity Reviewed International journal

    Amira Mira, Mohamed A. Sabry, @Kuniyoshi Shimizu, Fatma M. Abdel Bar

    MEDICINAL CHEMISTRY RESEARCH   1900

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Books

  • キノコの生理活性と機能 第8章 ヤマブシタケ

    呉静、清水邦義( Role: Joint author)

    シーエムシー出版  2021.10 

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    Language:Japanese   Book type:Scholarly book

  • キノコの生理活性と機能 第16章 霊芝(マンネンタケ)の臨床研究と含有成分

    清水邦義( Role: Joint author)

    シーエムシー出版  2021.10 

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    Language:Japanese   Book type:Scholarly book

  • 加工食品輸出の戦略的課題 第14章 国産農林水産物の機能性評価と産業化の動向と輸出展開

    〇清水邦義、中川敏法( Role: Joint author)

    筑波書房  2019.12 

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    Language:Japanese   Book type:Scholarly book

  • Molecular Design of Soybean Lipoxygenase Inhibitors Based on Natural Products, A Comprehensive Survey of International Soybean Research - Genetics, Physiology, Agronomy and Nitrogen Relationships

    I. Kubo, T. J. Ha, K. Shimizu( Role: Joint author)

    InTech  2013.3 

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    Responsible for pages:James E. Board (Ed.) DOI: 10.5772/52703.   Language:English   Book type:Scholarly book

    Other Link: http://www.intechopen.com/

  • Antioxidant Activity of Anacardic Acids In: Antioxidants and Biocides from Latin American Plants;

    N. Masuoka, K. Shimizu, I. Kubo( Role: Joint author)

    CABI Publishing (UK)  2012.11 

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    Responsible for pages:C.L. Cespedes, D.A. Sampietro, D.S. Seigler, Ed.   Language:English   Book type:Scholarly book

  • Naturally Occurring Antifungal Agents and Their Modes of Action. Fungicides for Plant and Animal Diseases

    I. Kubo, K. Shimizu, K. Fujita( Role: Joint author)

    InTech  2012.11 

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    Responsible for pages:D. Dhanasekaran, N. Thajuddin and A. Panneerselvam (Ed.)   Language:English   Book type:Scholarly book

    Other Link: http://www.intechopen.com/books/fungicides-for-plant-and-animal-diseases/naturally-occurring-antifungal-agents-and-their-modes-of-action

  • MANICOBA, A quercetin rich Amazonian dish In: Quercetin: Dietary Sources, Functions and Health Benefits

    I. Kubo, K. Shimizu, K. Nihei( Role: Joint author)

    Nova Science Publishers, Inc.  2012.11 

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    Language:English   Book type:Scholarly book

  • Anti-Salmonella Agents from Tanacetum Balsamita, A Brazilian Medicinal Plant, and their Application In: Antioxidants and Biocides from Latin American Plants

    I. Kubo, K. Fujita, K. Shimizu( Role: Joint author)

    CABI Publishing (UK)  2012.11 

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    Responsible for pages:C.L. Cespedes, D.A. Sampietro, D.S. Seigler, Ed.   Language:English   Book type:Scholarly book

  • キノコ学への誘い

    清水 邦義( Role: Joint author)

    海青社  2004.1 

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    Responsible for pages:「キノコの化学成分」67-82   Language:Japanese   Book type:Scholarly book

  • An update on antitumor activity of Angelica species

    Amira Mira, Kuniyoshi Shimizu

    Springer Singapore  2016.1 

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    Responsible for pages:363-371   Language:English  

    DOI: 10.1007/978-981-10-1085-9_15

  • 霊芝の多機能性薬理効果に関する近年の科学的検証

    2016 

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    Language:Japanese  

  • Anti-salmonella agents from the Brazilian medicinal plant tanacetum balsamita and their applications

    Isao Kubo, Ken Ichi Fujita, Kuniyoshi Shimizu

    CABI Publishing  2013.4 

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    Responsible for pages:239-253   Language:English  

  • Antioxidant activity of anacardic acids

    Noriyoshi Masuoka, Kuniyoshi Shimizu, Isao Kubo

    CABI Publishing  2013.4 

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    Responsible for pages:137-147   Language:English  

  • Maniçoba, a quercetin rich amazonian dish Antioxidative prospects

    2012 

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    Responsible for pages:129-154   Language:English  

    A large quantity of quercetin was characterized from a local dish, known as maniçoba in Pará, Brazil. The fresh leaf of Manihot esculenta Crantz (Euphorbiaceae), a principal ingredient for maniçoba, was found to contain a large amount of rutin or quercetin 3-O-rutinoside which was completely hydrolyzed to quercetin during cooking processes. Antioxidant activity of quercetin and its microfloral metabolites was examined. Quercetin inhibited the oxidation of linoleic acid catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, Type 1) with an IC50 of 4.5 μM, while rutin did not inhibit this oxidation up to 200 μM. The progress curves for the enzyme reaction indicate that quercetin shows slow binding kinetics. In the pseudoperoxidase activity, hydroperoxides slowly oxidize quercetin to a rather stable intermediate, 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone. A microfloral metabolite of quercetin and rutin after ingestion, 3,4-dihydroxyphenylacetic acid, also scavenged superoxide anion generated by xanthine oxidase and inhibited uric acid formation. The antioxidant activity observed with the methanol extract of maniçoba is due mainly to multifunctional quercetin's response.

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Presentations

  • 単一試験室および室間共同試験によるスギ材抽出成分(テルペン類)分析法の妥当性確認

    伊佐 亜希子1、藤田 弘毅1、井倉 則之1、藤本 登留1、清水 邦義1、谷 和樹2、小藤田 久義3、光永 徹4、芦谷 竜矢5、須原 弘登6、加藤 政和6 (1. 九大院農、2. 琉球大農、3. 岩大農、4. 岐阜大応生、5. 山形大農、6. 宮崎木技セ)

    第74回日本木材学会大会  2024.3 

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    Event date: 2024.3

    Language:Japanese  

    Venue:京都大学   Country:Japan  

  • エノキタケ各成長段階におけるノンターゲットリピドミクス

    ○范 佳欣1、金子 周平2、王 冬梅1、清水 邦義1 (1. 九⼤院農、2. 日本樹木医会)

    第74回日本木材学会大会  2024.3 

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    Event date: 2024.3

    Language:Japanese  

    Venue:京都大学   Country:Japan  

  • 東京都産軟化ウド根部における生理活性物質の探索と新規利用法の提案

    (九大院農) ○浦野優成、黄正萱、韓春光、永田真紀、王 冬梅、清水邦義 (東京都農林総合研究センター) 宮下智人、大槻優華

    第29回日本木材学会九州支部大会  2023.9 

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    Event date: 2023.9

    Language:Japanese  

    Venue:立命館アジア太平洋大学   Country:Japan  

  • Multi-medicinal mushroom Ganoderma lingzhi Invited International conference

    @Kuniyoshi Shimizu

    Ethnopharmacology: Globalization of Traditional Medicine  2023.3 

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    Event date: 2023.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:India  

  • Exploring the cosmeceuticals properties of the seagrass: Amamo (Zostera marina)

    2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Country:Japan  

  • 機能性表示無垢スギ材創出を目指したスギ含有抽出成分(セスキテルペン類)の分析JAS法開発への取り組み

    (九大農) @谷 和樹、@伊佐 亜希子、@藤田 弘毅、@藤本 登留、(山形大農)芦谷竜矢、(九大院農)@清水 邦義

    第73回日本木材学会大会  2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Venue:福岡大学   Country:Japan  

  • スギ内装材量の違いが心理的・生理的反応に及ぼす影響

    (九大農) @岸田文、@中島大輔、@谷和樹、@伊佐亜希子、@吉野紀美香、@藤田弘毅、@藤本登留、(トライウッド・木の家の健康を研究する会)渡邉雄一郎、(安成工務店・木の家の健康を研究する会)@安成信次、(九大院農)@清水 邦義

    第73回日本木材学会大会  2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Venue:福岡大学   Country:Japan  

  • エノキタケの経口摂取による皮膚水分量の改善:無作為化二重盲検プラセボ対照試験

    (九大院農) @永柄真澄、#范佳欣、@王冬梅、@伊佐亜希子、@永田真紀、@松本雅子、@清水 邦義 (熊本県立大学)@竹本直道 (農事組合法人 白茸館)@牟田伸一、@石川慧

    第73回日本木材学会大会  2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Venue:福岡大学   Country:Japan  

  • New benzaldehyde derivatives from the fruiting bodies of Hericium erinaceus with cytotoxic activity

    2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Country:Japan  

  • In vitro Metabolism of Hricenone C from Hericium erinaceus

    2023.3 

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    Event date: 2023.3

    Language:Japanese  

    Country:Japan  

  • 機能性表示無垢スギ材創出を目指したスギ含有抽出成分(テルペン類)の分析JAS法開発への取り組み

    (九大農) @谷 和樹、@伊佐 亜希子、@東房 健一、@藤本 登留、@藤田 弘毅、@清水 邦義

    第28回日本木材学会九州支部大会  2022.11 

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    Event date: 2022.11

    Language:Japanese  

    Venue:Zoomオンライン(熊本県)   Country:Japan  

  • スギ材内装由来の揮発性成分総量が心理的・生理的反応に及ぼす影響

    (九大院農)岸田文、中島大輔、土山真未、#孫良昊、谷和樹、伊佐亜希子、東房健一、藤田弘毅、藤本登留、清水邦義、(トライ・ウッド・木の家の健康を研究する会)@渡邉雄一郎、(安成工務店・木の家の健康を研究する会)@安成信次

    第28回日本木材学会九州支部大会  2022.11 

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    Event date: 2022.11

    Language:Japanese  

    Venue:Zoomオンライン(熊本県)   Country:Japan  

  • Anti-phototoxicity of Phenolic compounds from Entada phaseoloides leaves in Human Epidermal Keratinocytes Invited International conference

    #Mittraphab Yanisa, @Kuniyoshi Shimizu

    11th Asian Natural Product Conference (Q-AOS)  2022.6 

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    Event date: 2022.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Possible neuroprotective effect of amide alkaloids from some halophytes growing in Egypt Invited International conference

    #Ahmed Othman, @Kuniyoshi Shimizu

    11th Asian Natural Product Conference (Q-AOS)  2022.6 

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    Event date: 2022.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Ganoderma Triterpenoids: Hint for Understanding Multi-Medicinal effects of Ganoderma mushroom Invited International conference

    @Kuniyoshi Shimizu

    International Congress of SOCIETY FOR ETHNOPHARMACOLOGY, INDIA 2022  2022.4 

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    Event date: 2022.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:India  

  • アルガンオイルに含まれるアルガンサポニンの分析の検討

    #鈴木藍,@王冬梅,@Yhiya Amen,@竹本直道,@中嶋光敏,@礒田博子,@Tarik Ouchbani,@Fatima Ezzahra Janati Idrissi,@清水邦義

    第72回日本木材学会大会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学 岐阜大学   Country:Japan  

  • Anti-Phototoxicity of Phenolic Compounds from Acetone Extract of Entada phaseoloides Leaves in Human Epidermal Keratinocytes

    #Yanisa Mittraphab, @Yhiya Amen, @Maki Nagata, @Masako Matsumoto, @Dongmei Wang, @Kuniyoshi Shimizu

    2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Potential of Hibiscus sabdariffa Linn. for treatment of skin senescence and their mechanisms

    #Duanyang Wang, @Maki Nagata, @Masako Matsumoto, @Yhiya Amen, @Dongmei Wang, @Kuniyoshi Shimizu

    2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 霊芝(Ganoderma lingzhi)由来生理活性物質トリテルペノイドに関する研究

    #小松原陸, Yhiya amen,@Wu Yuchi,@竹本直道,@韓春光,@王冬梅,@清水邦義

    第72回日本木材学会大会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学 岐阜大学   Country:Japan  

  • スギ無垢材の抗ウイルス効果

    #松本雅子,@永田真紀,@井上由佳,@東房健一,@土山真未,@藤本登留,@清水邦義,@安成信次,@渡邉雄一郎

    第72回日本木材学会大会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学 岐阜大学   Country:Japan  

  • スギ材内装材由来の異なる香り濃度条件下における人の生理・心理応答解析

    #土山真未,@中島大輔,@東房健一,#孫良昊,@藤本登留,@清水邦義,@大貫宏一郎,@安成信次,@渡邉雄一郎

    第72回日本木材学会大会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学 岐阜大学   Country:Japan  

  • Utilization of natural resources based on scientific evidence for sustainable development-pharmaceutical, functional food, aroma, living environment Invited International conference

    @Kuniyoshi Shimizu

    Tunisia-Japan Symposium-Materials for Sustainable Development: Fundamentals & Applications  2022.3 

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    Event date: 2022.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Tunisia  

  • An analytical method for argan saponins in argan oil by using liquid chromatography quadrupole time-of-flight mass spectrometry International conference

    #Ran,Suzuki,@Wang Dongmei,@Yhiya Amen,@Naomichi Takemoto,@Fatima Ezzahra Janati Idrissi,@Tarik Ouchbani,@Mitsutoshi Nakajima, @Hiroko Isoda,@Kuniyoshi Shimizu

    Tunisia-Japan Symposium-Materials for Sustainable Development: Fundamentals & Applications  2022.3 

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    Event date: 2022.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Tunisia  

  • 前立腺に対する霊芝の効果 Invited

    @清水邦義

    泌尿器抗加齢医学研究会  2022.2 

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    Event date: 2022.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:沖縄万国津梁館(沖縄県)   Country:Japan  

  • Utilization of natural resources for sustainable development based on scientific evidence-Use for pharmaceuticals, functional foods, aromas, living environment- Invited International conference

    @Kuniyoshi SHIMIZU

    1st International Conference on Highland Germpalsm (ICHG) -Technological Innovation and Sustainable Development Based on Highland Germplasm-  2022.2 

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    Event date: 2022.2 - 2021.2

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • 機能性表示無垢スギ材創出を目指したスギ含有抽出成分(テルペン類)の分析JAS法開発への取り組み

    @清水邦義、@土山真未、@竹本直道、@中島大輔、@東房健一、@藤本登留(九州大学農学研究院)、@芦谷竜矢(山形大学農学部)、@小藤田久義(岩手大学農学部)、@光永徹(岐阜大学応用生物科学部)、 @楠本倫久、@橋田光、@大平辰朗(森林総合研究所)

    第4回樹木抽出成分研究交流会  2021.12 

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    Event date: 2021.12

    Language:Japanese  

    Venue:Zoomオンライン(香川大学)   Country:Japan  

  • How do we utilize natural resources based on scientific evidence? -Use for pharmaceuticals, functional foods, cosmetics, aromas, and living environment- Invited International conference

    @Kuniyoshi SHIMIZU

    International Conference on Natural Sciences, Technology, Islamic Studies, Social Sciences and Humanity (ICoNTISH)  2021.11 

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    Event date: 2021.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • Determination of Acetylcholinesterase Inhibiting Metabolites Through Untargeted Metabolomics Approach on Olive Cultivars

    2021.11 

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    Event date: 2021.11 - 2019.11

    Language:Japanese  

    Country:Japan  

  • 機能性食品開発に向けたコバネイナゴ抽出物の機能性成分の探索

    #齋木雅大、@永田真紀、@松本雅子、@Chunguang Han、@Dongmei Wang、@清水邦義

    第27回日本木材学会九州支部大会  2021.11 

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    Event date: 2021.11 - 2019.11

    Language:Japanese  

    Venue:Zoomオンライン(九州大学)   Country:Japan  

  • How should we utilize natural resources for sustainable development based on scientific evidence?-Use for pharmaceuticals, functional foods, aromas, living environment- Invited International conference

    @Kuniyoshi SHIMIZU

    International Conference-Natural Resources Governance Toward Sustainable Development  2021.11 

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    Event date: 2021.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • Characterization and Kinetic Studies of Proanthocyanidin Oligomers Complex Derived from Avocado Seed As a Promising Antidiabetic Agent Invited International conference

    @Thien Huu Nguyen, @Yhiya Amen, @Dongmei Wang, #Ahmed Othman, @Kuniyoshi Shimizu

    8th Asian Natural Product Conference (Q-AOS)  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Suspect and Non-target Screening of Emerging Contaminants in Wastewater Using LC-QTOF/MS in Data Independent Acquisition (DIA) Mode: Occurrence, Fate and Risk Assessment Invited International conference

    Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    8th Asian Natural Product Conference (Q-AOS)  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Bio-Activity Evaluation of Hibiscus sabdariffa Linn. in Skin Care and Isolation of Contributory Component International conference

    #Duanyang Wang, @Maki Nagata, @Masako Matsumoto, @Yhiya Amen, @Dongmei Wang, @Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • Suspect and non-target screening of emerging contaminants in wastewater using LC-QTOF/MS: An insight on occurrence, fate, risk, and wastewater management in Asia International conference

    @Asmaa Kamel El-Deen,@Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • The expansion of the promising value of Flammulina velutipes and the prospect of its sustainable development International conference

    #Jiaxin Fan,@Ahmed Ashour, @Ahmed Hassan, @Yhiya Amen, @Maki Nagata, @Masako Matsumoto, @Shuhei Kaneko, @Dongmen Wang, @Satoshi Ishikawa, @Shinich Muta, @Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • Utilization of Halophytes as a Source of Pharmaceutical Candidates International conference

    #Ahmed Othman, @Yhiya Amin, @Masako Matsumoto, @Maki Nagata, @Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • The Isolation and Identification of Hericenones in Hericium erinaceus (Yamabushitake) International conference

    #Ruan Yang, #Yanisa Mittraphab, #Ahmed Muhamed Othman, @Yhiya Amen, @Wang Dongmei, @Han Chunguang, @Mika Abe, @Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • Protective effects of acetone extract from Entada phaseoloides leaves on UVB-irradiated HaCaT keratinocytes International conference

    #Yanisa Mittrapha, @Maki Nagata, @Massako Matsumoto, @Kuniyoshi Shimizu

    Kyushu University Asia Week 2021  2021.10 

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    Event date: 2021.10

    Language:English  

    Country:Japan  

  • 森林資源(木の家・キノコ)の認知機能改善効果 Invited

    #清水邦義、@中島大輔、@土山真未、@竹本直道、@永田真紀、@松本雅子、@永柄真澄、@大貫宏一郎

    シンポジウム3 ぼけ(認知症)に克つ 第21回日本メンズヘルス医学会  2021.9 

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    Event date: 2021.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:オンライン   Country:Japan  

  • How do we utilize natural materials based on scientific evidence? -Use for pharmaceuticals, functional foods, cosmetics, aromas, and living environment- Invited International conference

    The 2nd International Conference Series on Biodiversity Status Update of North Borneo  2021.9 

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    Event date: 2021.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • How to utilize natural products as the valuable products -Medicine, Functional Food, aroma, Woody house Invited International conference

    Academic Seminar International Conference (2ND ASIC)  2021.8 

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    Event date: 2021.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Chemical and biological investigation of xero-halophyte Bassia indica growing in Egypt

    #Ahmed Othman, @Yhiya Amen, @Masako Matsumoto, @Maki Nagata, @Kuniyoshi Shimziu

    2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Study of a glucosylceramide as functional food properties in Flammulina velutipes (Enokitake)

    #Jiaxin Fan, #Asmaa Kamal El-Deen, Ahmed Ashour, Ahmed Ramadan Hassan, Yhiya Amen, @Naomichi Takemoto, @Maki Nagata, @Masako Matsumoto , @Dongmei Wang, Satoshi Ishikawa, Shinichi Muta, @Kuniyoshi Shimizu

    2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • イナゴの含有成分分析及び機能性評価

    #齋木 雅大、@竹本 直道、@永田 真紀、@松本 雅子、@王 冬梅、@Amen Yhiya、@清水 邦義

    第71回日本木材学会大会  2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • Bio-Activity Evaluation of Hibiscus sabdariffa Linn. in Skin Care and Isolation of Contributory Component

    #Duanyang Wang, @Maki Nagata, @Masako Matsumoto, @Yhiya Amen, @Dongmei Wang, @Kuniyoshi Shimizu

    2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Chemical investigation and biological activities of Entada phaseoloides leaves

    2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • LCMS-Based Untargeted Metabolomics of Stipe, Pileus, and Spore of Ganoderma lingzhi

    #Renandini Danistha, Dedi Satria, Rogers Mwakalukwa, @Kuniyoshi Shimizu

    2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Lifestyles of Health and Sustainability (LOHAS) concept for the better future: How to utilize natural products as the valuable products -Medicine, Functional Food, aroma, Woody house Invited International conference

    New Challenges in Pharmaceutical Research and Education in Egypt  2021.3 

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    Event date: 2021.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:Egypt  

  • スギ材の香りがヒトの脳内視覚性注意に与える影響. 第3回樹木抽出成分討論会

    中島大輔、吉村友里、@渡邉裕一郎((株)トライ・ウッド)、@安成信次((株)安成工務店)、@大貫宏一郎(近畿大学産業理工学部)、藤本登留、清水邦義

    第3回樹木抽出成分討論会  2020.11 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  • Effects of Japanese cedar scent on the human brain function Invited International conference

    Taisuke Nakashima, Akiyoshi Honden, @Minkai Sun, Yuri Yoshimura, @Toshinori Nakagawa, @Hiroya Ishikawa, Jun Nagano, Yuki Yamada, Tsuyoshi Okamoto, @Yuichiro Watanabe, @Shinji Yasunari, @Koichiro Ohnuki, Noboru Fujimoto, Kuniyoshi Shimizu.

    Asian Natural Product Conference (Q-AOS)  2020.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Cultivar-specific metabolic profiling of olive leaves cultivars by LCMS based non-targeted metabolomics for the determination of AChE inhibitor metabolites Invited International conference

    #Rogers Mwakalukwa, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2020.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • モウソウチク(Phyllostachys pubescens)稈由来リグニンの分解生成物中に含まれる化合物の生理活性

    #廣島 将大,栫 拓巳,堤 祐司,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:鳥取県   Country:Japan  

    モウソウチク(Phyllostachys pubescens)は日本国内に広く生育するタケの一種である。竹材の高付加価値的利用を考える上で、その主要な構成要素であるリグニンに着目し、薬理学的効果を指向した検討を行った。アルカリ抽出を起点としてモウソウチク稈由来リグニン分解生成物を分画し、分画物が5種のヒト由来細胞に与える影響を検討した。分画物中の比較的低極性の化合物群が今回使用した多くの細胞に対し細胞生存率を低下させる活性を示したが、ヒト皮膚細胞に関しては癌細胞であるG-361に対してのみ同様の活性が見られた。活性画分を分画し、6種の化合物を単離した。単離化合物による試験結果も報告する。

  • Postprandial hyperglycemia lowering effect of metabolites isolated from olive mill wastes (OMW)―An inhibitory activity on α-glucosidase and α-amylase enzymes―

    #MWAKALUKWA Rogers,AMEN Yhiya,SHIMIZU Kuniyoshi

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:English   Presentation type:Oral presentation (general)  

    Venue:鳥取県   Country:Japan  

    Diabetes is characterized by chronic hyperglycemia resulting from either, when the pancreas does not produce enough insulin (type 1), or when the body cannot effectively use the insulin it produces (type 2). The raise of blood glucose level, postprandially, results from hydrolysis of carbohydrates catalyzed by α-glucosidase and α-amylase. Thus, inhibition of these enzymes results into massive reduction of postprandial blood glucose levels ? a major cause of diabetes. In the present study, we report the isolation and anti-diabetic activity (inhibitory effect on α-glucosidase and α-lipase) of eight (8) compounds, one of them being novel, from olive mill wastes (OMW). Additionally, we investigated the enzyme kinetic analysis of the most active compounds to assist the possible characterization of the inhibition mechanisms involved. We observed that four compounds, 1, 2, 4 and 7, had higher activity against both enzymes. The kinetics studies of these compounds revealed that oleanolic acid 1 and luteolin-7-O-glucoside 7 inhibit α-glucosidase in a mixed-type fashion, while 1-acetoxypinoresinol 4 does it uncompetitively. Both mixed type and uncompetitive inhibition are similar to noncompetitive inhibition except that binding of the substrate or the inhibitor affect the enzyme’s binding affinity for the other. Thus for both, mixed type and uncompetitive, Ki value, which measures the affinity of the inhibitor for an enzyme was greater than 1 (Ki >1). Even though the novel compound, 3,4-dihydroxyphenyl-2-ethoxyethanol 5 exhibited poor activity, it helped to study the SAR for compounds of same class (hydroxytyrosol acetate 6 and hydroxytyrosol), whereby we clearly observed that both methoxylation and esterification of different positions does not influence their activity against the enzymes. This work attracts more attention to OMW as a potential source of lead compounds for structural modification to improve and develop new anti-diabetic drugs.

  • Anti-Hyperglycemic Effect of Pholiota adiposa on Human Subjects and isolation of active components

    2020.3 

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    Event date: 2020.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • スギ材部由来の揮発性成分が覚醒時および睡眠時のヒトに与える影響の生理学的・心理学的評価

    #楊 楽,中島 大輔,野村 健,工藤 崇,吉村 友里,阿部 三佳,竹本 直道,王 冬梅,@渡邊 雄一郎,@大貫 宏一郎,藤本 登留,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

    本研究では、津江スギから得られた精油が、覚醒時および睡眠時のヒトの生理・心理応答にどのような影響を及ぼすかについて検討した。 本実験は九州大学倫理委員会の承認を得て行い、被験者には参加への同意を得た。夜間における睡眠に及ぼす影響を検証する為に睡眠実験を実施し、脳波および心電図、血圧、脈拍、唾液コルチゾール、sIgAを測定し、ピッツバーグ睡眠質問票、気分プロフィール検査、香りに対する主観評価などを測定した。また、室内の香り成分を含む空気を捕集しGC/MS分析装置を用いて揮発性成分の定量・定性的分析を行った。 その結果、スギの精油の呈示によりネガティブな気分状態が低下し、ヒトの心理面において好ましい影響を及ぼすことが明らかになった。また、睡眠導入時にスギの精油を呈示することにより、ノンレム睡眠の4段階の時間を延長させる可能性が示唆された。

  • スギ材を用いた木質居住環境の香りがヒトの脳内の視覚性注意へ与える影響

    中島 大輔,本傳 晃義,吉村 友里,孫 旻愷,中川 敏法,山田 祐樹,岡本 剛,@渡邉 雄一郎,@安成 信次,@大貫 宏一郎,藤本 登留,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:鳥取県   Country:Japan  

    ヒトの精神的状態は居住環境に影響される。近年、電気生理学的手法によってヒトの脳に香りが与える影響が検討されている。しかしながらそれらは主に覚醒度に関する評価であり、居住環境の香りによる脳内の認知処理過程を段階的に明らかにしたものは知る限り存在しない。そこで、スギの無垢材と樹脂系建材を内装とする2棟を建設し、木質居住環境中の揮発性成分をGC/MSにより定量化し、同時に若年成人18名を対象に初期視覚野成分P100、非自発的注意成分ミスマッチ陰性電位(MMN)、自発的注意成分P300を測定し、脳内の認知処理過程を段階的に評価した。その結果、セスキテルペン類の濃度はスギ無垢材等において有意に高かった (P < 0.05)。また、視覚性MMN成分はスギ無垢材棟においてのみ顕著に認められた(P < 0.05)。よって、スギ無垢材を内装に用いた場合、その主な揮発性成分であるセスキテルペン類が非意図的な注意機能を初期の視覚野レベルで高める可能性が示唆された。

  • 内装の異なる木質住環境がヒトの生理・心理応答に及ぼす影響

    野村 健,小山 眞,工藤 崇,阿部 三佳,吉村 友里,高濱 瞭子,常冨 愛香里,原口 翼,王 冬梅,中島 大輔,@東房 健一,@渡邉 雄一郎,@安成 信次,@大貫 宏一郎,藤本 登留,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:鳥取県   Country:Japan  

    スギ(Cryptomeria japonica)は日本固有の主要樹種であり、古来より様々な用途に用いられてきた。スギ材から放出される「香り成分」はヒトの交感神経活動を抑制し、心身をリラックスさせる効果があることはよく知られている本研究では、スギ無垢材および樹脂系建材を内装に用いた異なる木質住環境がヒトの生理・心理応答にどのような影響を及ぼすかについて比較検討を行った。その結果、室内に揮発性成分のセスキテルペン類を多く含むスギの乾燥木材を内装に用いた部屋は、塗装やビニールクロスなどを内装に用いた部屋に比べリラックス効果が高く、その影響により記憶に関連する脳機能が促進し正答率が向上する可能性が示唆された。

  • ヤマブシタケ子実体発育過程における生理活性成分ヘリセノン類の分析

    #太田 早紀子,#阮 暘,#ASMAA Kamal El-deen,竹本 直道,YHIYA Amen,王 冬梅,金子 周平,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:鳥取県   Country:Japan  

    ヤマブシタケはサンゴハリタケ科サンゴハリタケ属に属する食用きのこである。特にヤマブシタケに含まれるヘリセノン類は神経成長因子 (NGF) の合成促進などの活性を示すことが報告されている。本研究では、子実体発育に伴いどのように生理活性成分が変化するのか、液体クロマトグラフ四重極飛行時間型質量分析装置 (LC-Q-TOF/MS) を用いて二次代謝産物であるヤマブシタケ抽出物のヘリセノン類の挙動の解明、分析方法の確立および定量化することを目的とした。 ヤマブシタケからメタノール抽出を行い、そのヘキサン画分より得られたヘリセノン類粗精製物を用いて、高速液体クロマトグラフィーによるヘリセノン類の分析方法を検討し、LC-Q-TOF/MSにより各ピークの同定を行った。この分析条件をもとに、ヘリセノン類の抽出溶媒の検討およびステージごとのヘリセノン類の定量を進めているため、詳細は当日報告する。

  • スギ板材に含まれる揮発性成分の空間的挙動に関する研究

    竹本 直道,吉村 友里,阿部 三佳,王 冬梅,@東房 健一,@簗瀬 和彦,@渡辺 久美子,@中川 敏法,藤本 登留,清水 邦義

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese  

    Venue:鳥取県   Country:Japan  

    乾燥方法によって、スギ板材の揮発性成分は異なることが報告されている。また、異なる乾燥法(高温乾燥・中温乾燥・地熱乾燥・天然乾燥)で抽出成分(揮発性成分)への影響を調査した結果、いくつかのセスキテルペン類、ジテルペン類で統計的有意差が認められるとともに、地熱乾燥は天然乾燥に近い成分組成であると考えられた。加えて、ジテルペン類に関しては、地熱乾燥材に多く含まれており、耐腐朽性に優れている可能性が示された。しかし、このような成分は仕上げからの時間経過に伴い、板材中から揮発するなどして減少することも予想され、その挙動を把握することが重要であると考えた。しかし、これまで板材中の揮発性成分の挙動に関する報告はない。そこで、本研究ではスギ板材に含まれる揮発性成分および含水率の空間的な挙動に関する評価方法の確立および調査を実施した。

  • Isolation, Characterization and in Vitro Antioxidant Activity of Polysaccharide from Pholiota adiposa

    2020.3 

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    Event date: 2020.3

    Language:English  

    Country:Japan  

  • Ganoderic acid Df, a potent aldose reductase inhibitor isolated from the fruiting body of medicinal mushroom, Ganoderma lucidum International conference

    S. Fatmawati, K. Shimizu, R. Kondo

    11th Eurasia Conference on Chemical Sciences,  2010.10 

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    Event date: 2010.10

    Presentation type:Oral presentation (general)  

    Country:Jordan  

  • タモギタケ(Pleurotus cornucopiae)の生理活性

    孟天暁、清水邦義、大賀祥治、近藤隆一郎

    第17回日本木材学会九州支部  2010.8 

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    Event date: 2010.8

    Presentation type:Oral presentation (general)  

    Venue:福岡大学   Country:Japan  

  • Anti-melanogenesis of quercetin and its derivatives from Allium cepa in cultured melanoma cells

    E. T. Arung, K. Shimizu, R. Kondo, H. Ishikawa

    2010.7 

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    Event date: 2010.7

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • The prevention effect of medicinal mushroom, Ganoderma lucidum on benign prostatic hyperplasia Invited International conference

    K. Shimizu

    2nd East Asian International Symposium on Natural Resources for Medicine  2010.6 

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    Event date: 2010.6

    Presentation type:Oral presentation (general)  

    Country:Korea, Republic of  

  • 『アカルを用いた多機能性消臭資材の開発』

    清水 邦義

    アグリビジネス創出フェアin 九州  2007.11 

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    Venue:久留米リサーチセンタービル(展示場)   Country:Japan  

  • 霊芝(Ganoderma lucidum)の前立腺肥大抑制効果

    清水 邦義、劉 潔、田村 貞明、野田潔、小西史子、隈本正一郎、金子周平、水海吉太郎、近藤 隆一郎

    第十回日本キノコ学会  2006.9 

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    Venue:秋田県立大学秋田キャンパス   Country:Japan  

  • Anti-androgenic Effect of Ganoderma lucidum International conference

    J. Liu, K. Shimizu, F. Konishi, S. Kumamoto, R. Kondo

    2006' International Symposium for Pharmaceutical Sciences in Beijing  2006.10 

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    Country:Japan  

  • Prevention Effect of Bone Loss in Calcium Deficient Ovariectomized Rats by the Ethanol Extract of Ganoderma lucidum Invited International conference

    K. Shimizu, I. Miyamoto, R. Kondo

    2006' International Symposium for Pharmaceutical Sciences in Beijing  2006.10 

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    Presentation type:Oral presentation (general)  

    Country:Japan  

  • 「自然の恵み」を科学する~健やかになる「辛味」と「苦味」~ Invited

    清水 邦義

    いとしまサイエンスキャラバン  2006.10 

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    Presentation type:Oral presentation (general)  

    Venue:前原市商工会館   Country:Japan  

  • 『ロハスな身近な自然の機能~きのこや樹木からのヒント~』 Invited

    清水 邦義

    第六回ネットワーク勉強会(ひびきのエコサロン)  2007.1 

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    Presentation type:Oral presentation (invited, special)  

    Venue:北九州学術研究都市 産学連携センター2F 中会議室2 (北九州市若松区ひびきの2-1)   Country:Japan  

  • マンネンタケ抽出物からの抗男性ホルモン活性成分

    劉 潔、清水 邦義、小西 史子、隈本 正一郎、近藤 隆一郎

    日本農芸化学会  2007.3 

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    Presentation type:Oral presentation (general)  

    Venue:東京都(口頭発表)   Country:Japan  

  • 『自然と人のインターフェース解析~香りと人~ -香り-化学構造-量-心理・生理応答-数値化-システム化』 Invited

    清水 邦義

    JST Innovation Bridge 九州大学 研究シーズ発表会~機械分野、医歯薬バイオ分野~  2007.3 

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    Presentation type:Oral presentation (general)  

    Venue:秋葉原コンベンションホール(秋葉原ダイビル5F)(東京都千代田区外神田1-18-13 )   Country:Japan  

  • 『天然物」と「人」の生理・感性相互作用に着目した自然と人のインターフェース解析』 Invited

    清水 邦義

    九州大学教育・研究の最前線~九州大学総合研究博物館 特別展示~第六回P&P研究成果一般公開~  2007.5 

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    Presentation type:Symposium, workshop panel (public)  

    Venue:九州大学箱崎キャンパス50周年記念講堂   Country:Japan  

  • マンネンタケからの前立腺ガン細胞の増殖抑制成分

    劉潔、清水邦義、近藤隆一郎

    第57回日本木材学会  2007.8 

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    Venue:広島市   Country:Japan  

  • 自然由来揮発成分のビジランスに及ぼす影響

    清水邦義、玉泉真弓、村上千尋、水野谷航、近藤隆一郎、河邉隆寛、小崎智照、大貫宏一郎、石橋圭太、泉 龍介

    第57回日本木材学会  2007.8 

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    Venue:広島市   Country:Japan  

  • The inhibitory compounds from Ganoderma lucidum on osteoclast formation International conference

    J. Shiono, I. Miyamoto, J. Liu, K. Shimizu, R. Kondo

    Asian Symposium for Pharmaceutical Science in JSPS Asian Core Program  2007.10 

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    Country:Japan  

  • The anti-androgenic effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum International conference

    J. Liu, K. Shimizu, F. Konishi, S. Kumamoto, R. Kondo

    Asian Symposium for Pharmaceutical Science in JSPS Asian Core Program  2007.10 

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    Country:Japan  

  • Bio-Activity Evaluation of Hibiscus sabdariffa Linn. in Skin Care and Isolation of Contributory Component International conference

    #Duanyang Wang, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2021.2 

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    Event date: 2021.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • LCMS-Based Untargeted Metabolomics of Stipe, Pileus and Spore of Ganoderma lingzhi International conference

    #Renandini Danistha, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2021.2 

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    Event date: 2021.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • From Waste To Medicine: Potential Avocado (Persean americana Mill) Seed Derived Compounds For The Treatment Of Diabetes International conference

    #Nguyen Huu Thien, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2021.2 

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    Event date: 2021.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • ウィズコロナ時代に対応した無垢木材の開発戦略 Invited

    清水邦義

    農林水産技術セミナー  2021.1 

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    Event date: 2021.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン   Country:Japan  

  • 機能性成分とアンチエイジング

    清水邦義

    日本抗加齢医学会  2020.12 

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    Event date: 2020.12

    Language:Japanese  

    Country:Japan  

  • LC-QTOFMS・データベース活用時の標準物質の有無による成分分析における利便性と予期せぬ挙動への対応困難さ~汚泥中微量有機化合物・キノコ中機能性脂質分析を例として~ Invited

    清水邦義

    第167回 質量分析関西談話会  2020.12 

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    Event date: 2020.12

    Language:Japanese  

    Country:Japan  

  • Effects of secondary metabolites of Entada phaseoloides leaves on UV radiation damage in human keratinocytes and fibroblasts cell lines International conference

    #Yanisa Mittraphab, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2020.10 

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    Event date: 2020.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Liquid chromatography–high-resolution mass spectrometry-based analysis of ceramides in Aspergillus oryzae and Flammulina velutipes International conference

    2020.10 

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    Event date: 2020.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:福岡県   Country:Japan  

  • Evaluation of the Anti-Hyperglycemic Effect of Pholiota adiposa on Human Subjects and the bio-guided isolation of active components Invited International conference

    Asian Natural Product Conference (Q-AOS)  2020.9 

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    Event date: 2020.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Metabolomics Analysis Revealed Alteration of Lingzhi (Ganoderma lingzhi) metabolites during developmental stages Invited International conference

    Asian Natural Product Conference (Q-AOS)  2020.9 

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    Event date: 2020.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Application of D-Limonene as a Bio-Based Solvent in Low Density-Dispersive Liquid-Liquid Microextraction of Acidic Drugs from Aqueous Samples Invited International conference

    #Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Asian Natural Product Conference (Q-AOS)  2020.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Sleep Enhancement by Saffron Extract in Randomized control trial Invited International conference

    @Akemi Nishide, @Keiko Ohnuki, @Tomonari Watanabe, @Yoshiteru Nagaregawa, Kuniyoshi Shimizu, @Koichiri Ohnuki.

    Asian Natural Product Conference (Q-AOS)  2020.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Propolis of Stingless Bees for Skin whitening agent Invited International conference

    @Enos Tangke Arung, @Syafrizal, @Swandari Parawita, @Yadi, @Sukemi, @Nataniel Tandirogang, Yhiya Amen, Kuniyoshi Shimizu, @Hiroya Ishikawa.

    Asian Natural Product Conference (Q-AOS)  2020.5 

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    Event date: 2020.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • エノキタケ(大木白雪919)含有主要セラミドの定量分析

    #高嶋 快土,竹本 直道,@上田 景子,@石川 慧

    第70回日本木材学会  2020.3 

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    Event date: 2020.3

    Language:Japanese  

    Venue:鳥取県   Country:Japan  

    大木白雪919というエノキタケ品種に含まれるグルコシルセラミドの定量的分析のため、有機溶媒での抽出とHPLCによる分析を行った。エノキタケから単離されたENH-7という成分について、抽出溶媒と分析方法の最適化を図り、様々な条件で検討しクロロホルムでの抽出と、水・メタノールの混合溶媒を移動相に用いた逆走HPLCによる分析手法を確立した。今後は抽出のスケールを上げ、セラミド以外の成分の除去のため前処理技術の検討も行いより分析の精度を上げ、大木白雪919に含まれるENH-7の正確な含有量を把握する予定である。

  • 日本固有の住環境由来素材(畳、スギ)の香りのヒトへの影響解析と高機能性快適住環境創出に向けた戦略 Invited

    清水 邦義

    日本ハーブ療法研究会 第7回学術集会  2019.12 

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    Event date: 2019.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:埼玉大学 教育機構 全学講義棟1号館 1-301室   Country:Japan  

  • 木材のヒトへの良さの科学的検証と将来展望 ~いかに機能性を証明し、高付加価値・新市場を獲得するか~ Invited

    清水 邦義

    第10回日本木の家づくりサミット in 博多  2019.11 

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    Event date: 2019.11 - 2019.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡県   Country:Japan  

    一般的に木の家はヒトにとって良いといわれている。しかし、その効果を科学的に検証した研究は少ない。この講演は木の家の機能性を証明しようとする重要な発表である。将来的には木の家に高付加価値を付け、新市場が開ける可能性がある。

  • 香辛料の機能性研究~機能性表示と香りの多機能性~ Invited

    清水 邦義

    第34回日本香辛料研究会  2019.11 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:九州大学病院 コラボステーションⅠ(福岡市)   Country:Japan  

  • Lifestyles of Helth and Sustinability (LOHAS) concept for the better future : How to utilize natural products as the valueable products-Medicine,Functional Food, Aroma,Woody house

    Kuniyoshi Shimizu

    1st Gunma University Center for Food Science and Wellness (GUCFW) International Symposium and ALCA/JST workshop  2019.11 

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    Event date: 2019.11

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Lifestyles of Health and Sustainability (LOHAS) concept for the better future: How to utilize natural products as the valuable products -Medicine, Functional Food, Aroma, Woody house- Invited International conference

    Kuniyoshi Shimizu

    Natural Product From Tropical Highland Rainforest  2019.11 

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    Event date: 2019.11

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Development of natural products research from tropical rainforest How to utilize natural products as the valuable products -Medicine, Functional Food, Aroma, Woody house- Invited International conference

    Kuniyoshi Shimizu

    World Class Professor Program 2019  2019.10 

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    Event date: 2019.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Lifestyles of Health and Sustainability (LOHAS) concept for the better future: How to utilize natural products as the valuable products-Medicine, Functional Food, Aroma, Woody house- Invited International conference

    Kuniyoshi SHIMIZU

    The 409th Symposium on Sustainable Humanosphere and the 9th International Symposium for Sustainable Humanosphere  2019.10 

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    Event date: 2019.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • エキスが細胞の凱日リズムに及ぼす影響

    清水邦義、永田真紀、松本雅子、Yhiya Amen、工藤崇、望月雅友、谷口薫

    日本生薬学会第66回年会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:北里大学 薬学部   Country:Japan  

  • The importance of triterpenoids for efficient utilization of multi-medicinal mushroom, Ganoderma lingzhi-Analysis of metabolites during developmental stages Invited International conference

    Kuniyoshi SHIMIZU,Dedi SATRIA

    The 10th International Medicinal Mushroom Conference  2019.9 

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    Event date: 2019.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:China  

  • The importance of triterpenoids for efficient utilization of multi-medicinal mushroom, Ganoderma lingzhi-Analysis of metabolites during developmental stages- Invited International conference

    Kuniyoshi SHIMIZU,Dedi SATRIA

    The 10th International Medicinal Mushroom Conference Third Circular  2019.9 

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    Event date: 2019.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Cytotoxicity of lignin-derived compounds isolated from bamboo (Phyllostachys pubescence) on cancer cell line International conference

    Hiroshima Shota, Kakoi Takumi, Hayashi Junya, Tsutsumi Yuji,Shimizu Kuniyoshi

    1st International Lignin Symposium (64th Lignin Symposium)  2019.9 

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    Event date: 2019.9

    Language:English  

    Country:Japan  

  • 覚醒時および睡眠中の生理的・心理的評価および揮発性成分分析を組み合わせた評価系の確立

    楊 楽、吉村友里、中島大輔、野村健、工藤崇、阿部三佳、小山眞、竹本直道、渡邊雄一郎、大貫宏一郎、藤本登留、清水邦義

    第26回日本木材学会九州支部大会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:宮崎市民プラザ   Country:Japan  

  • 仕上げからの時間経過に伴う地熱乾燥したすぎ板材の揮発性成分分析に関する研究

    竹本直道、吉村友里、阿部三佳、簗瀬和彦、渡辺久美子、中川敏法、藤本登留、清水邦義

    第26回日本木材学会九州支部大会  2019.9 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:宮崎市民プラザ(宮崎県)   Country:Japan  

  • 乾燥スギ内装材を用いた居住空間が作業課題における心理および脳機能 に与える影響

    中島大輔、小山眞、野村健、工藤崇、高濱瞭子、阿部三佳、吉村友里、渡邉雄一郎、安成信次、大貫宏一郎、藤本登留、清水邦義

    第26回日本木材学会九州支部大会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:宮崎市民プラザ(宮崎県)   Country:Japan  

  • 異なる木質住環境がヒトの睡眠の質に及ぼす影響に関する 電気生理学的研究

    野村健、小山眞、工藤崇、阿部三佳、吉村友里、中島大輔、岡本剛、渡邉雄一郎、安成信次、大貫宏一郎、藤本登留、清水邦義

    第26回日本木材学会九州支部大会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:宮崎市民プラザ(宮崎県)   Country:Japan  

  • スギ無垢材もしくは非無垢材を内装に使用した住環境におけるヒトへの生理学的・心理学的影響

    本傳晃義、小山眞、野村健、工藤崇、阿部三佳、吉村友里、中島大輔、渡邉雄一郎、安成信次、大貫宏一郎、藤本登留、清水邦義

    第26回日本木材学会九州支部大会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:宮崎市民プラザ(宮崎県)   Country:Japan  

  • Mast cell stabilizing effect of the isolated compounds from olive mill waste following allergic sensitization - A bioassay-guided fractionation approach

    Rogers Mwakalukwa, Ahmed Ashour, Yhiya Amen, Yasuharu Niwa, Sonam Tamrakar, Toshihiro Miyamoto and Kuniyoshi Shimizu

    2019.9 

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    Event date: 2019.9

    Language:English  

    Country:Japan  

  • Lifestyles of Health and Sustainability (LOHAS) concept for the better future: How to utilize natural products as the valuable products-Medicine, Functional Food, Aroma, Woody house- Invited International conference

    Kuniyoshi Shimizu

    2019.9 

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    Event date: 2019.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • 環境ストレッサーに対するビワ種子粉末の機能性評価

    清水邦義、永田真紀、松本雅子、Yhiya Amen ,高谷泰行、谷口薫

    第36回和漢医薬学会学術大会  2019.9 

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    Event date: 2019.8 - 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:富山国際会議場   Country:Japan  

  • Lifestyles of Health and Sustainability (LOHAS) for the better future -Functional Food, Aroma, Woody house- How to utilize natural products Invited International conference

    Kuniyoshi SHIMIZU

    2019.8 

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    Event date: 2019.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Stress Amelioration Potentials of Shiikuwasha (Citrus Depressa Hayata) Essential Oil International conference

    Yonathan Asikin,Eriko Haga, Kuniyoshi Shimizu,Miyako Kusano, Hirosuke Oku, Koji Wada

    ACN (Asian Congress of Nutrition) 2019  2019.8 

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    Event date: 2019.8

    Language:English  

    Country:Japan  

  • いぐさがヒトの睡眠に与える影響ーEffects of dried common rush (Juncus effusus) on human sleepー

    第42回日本神経科学大会  2019.7 

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    Event date: 2019.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • New potent α-glucosidase inhibitory glucoside from Lycium schweinfurthi

    Ahmed ASHOUR、El-sayed MANSOUR、Kadria AHMAD、Kuniyoshi SHIMIZU

    第69回日本木材学会大会(函館大会)  2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • Ursolic acid, isolated from the leaves of loquat (Eriobotrya japonica) inhibited osteoclast differentiation through specific target

    Hui Tan、Kuniyoshi Shimizu

    第69回日本木材学会大会(函館大会)  2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • 竹幹表皮エキスの美白作用機序解析と化粧品の機能性評価

    熊谷健太、東知世、田口文、竹本拓矢、清水邦義

    第69回日本木材学会大会(函館大会)  2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • モウソウチク(Phyllostachys pubescens)稈由来リグニンの分解生成物中に含まれる抗癌活性成分の探索

    廣島将大、栫拓巳、堤祐司、清水邦義

    第69回日本木材学会大会(函館大会)  2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • Phytochemical investigation of bamboo peel and biological activities related to skin

    2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • Isolation and identification of anti-allergic compounds from Olive Mill Wastes (OMW)

    2018.3 

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    Event date: 2018.3

    Language:English  

    Country:Japan  

  • トドマツ(Abies sachalinensis)抽出物の生理活性

    中川敏法,Ahmed Ashour, Ahmed Allam, 古場有里恵, 大貫宏一郎, 清水邦義

    2018.3 

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    Event date: 2018.3

    Language:Japanese  

    Country:Japan  

  • Analysis of Ganoderma lingzhi (Reishi) metabolite during growth stages: a metabolomics approach

    The 68th Annual Meeting of Japan Wood Research Society in Kyoto  2018.3 

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    Event date: 2018.3

    Language:English  

    Country:Japan  

  • Three new Erinacerins from the fruiting bodies of Hericium erinaceums

    Ashour A, Allam A, Amen Y, Shimizu K

    2018.3 

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    Event date: 2018.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • スギ材を使用した建物の室内空間における揮発性成分の分析およびその季節変動Ⅱ

    西條裕美, 吉村友里, 本傳晃義, 藤田弘毅, 藤本登留, 清水邦義, 渡邉雄一郎, 岡本元一, 井上伸史, 安成信次, 永野純, 山田祐樹, 岡本剛, 大貫宏一郎, 石川洋哉

    第67回日本木材学会大会  2017.3 

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    Event date: 2017.3

    Language:Japanese  

    Country:Japan  

  • オリーブオイル搾油残渣に含まれる抗アレルギー活性成分

    #岸川明日香、@Yhiya Amen、@清水邦義

    第67回日本木材学会大会  2017.3 

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    Event date: 2017.3

    Language:Japanese  

    Venue:九州大学   Country:Japan  

  • 乾燥処理がスギ板材のメタノール抽出成分に与える影響

    奥田拓、村野朋哉, 三好悠, 亀井裕人、佐々木隆雄、三枝康弘、和田善行, 湊俊司、阪井彰一、千里泰三, 中川敏法、藤本登留、清水邦義

    第67回日本木材学会大会(福岡大会)  2017.3 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:アクロス福岡(福岡   Country:Japan  

  • ヤマブシタケ(Hericium erinaceum)に含まれる機能性成分の生育ステージごとの比較分析

    竹本直道,中川敏法,アハメドアラム,清水邦義,大貫宏一郎,永田敬文,森川 茂

    第67回日本木材学会大会(福岡大会)  2017.3 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:アクロス福岡(福岡   Country:Japan  

  • 生育段階が異なる霊芝(Ganoderma lingzhi)のトリテルペノイド含量および多糖類含量

    中川敏法、Zhu Qinchang, Sonam Tamrakar, Yhiya Amen, 森康浩, 金子周平, 川島寛子, 奥薗高太郎, 井上義之, 大貫宏一郎, 清水邦義

    第67回日本木材学会大会(福岡大会)  2017.3 

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    Event date: 2017.3

    Language:Japanese  

    Country:Japan  

  • 異なるスギ材を使用した居住空間がヒトの心理および作業性に及ぼす影響

    本傳晃義、羽賀栄理子、中島大輔、鷲岡ゆき、吉村友里、藤本登留、清水邦義、山田祐樹、永野純、岡本剛, 石川洋哉, 大貫宏一郎、渡邉雄一郎、岡本元一、井上伸史、安成信次

    第67回日本木材学会大会(福岡大会)  2017.3 

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    Event date: 2017.3

    Language:Japanese  

    Venue:九州大学・アクロス福岡(福岡)   Country:Japan  

  • Isolation and identification of anti-allergic compounds in the fruiting body of Pholiota adiposa mushroom

    Nguyen Thi Kim Thoa, Yhiya M. Amen, Kuniyoshi Shimizu, Kenshin Hiromatsu.

    The 67th annual meeting of Japan Wood Research Society in Fukuoka  2017.3 

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    Event date: 2017.3

    Language:English  

    Country:Japan  

  • Triterpenoids: Hint for Understanding Multi-Medicinal effects of Ganoderma mushroom Invited International conference

    Shimizu K

    International Mini Symposium of Natural Products Chemistry and Life Sciences in UGSAS-GU  2016.3 

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    Event date: 2017.3

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Japan  

  • Ling Zhi (霊芝): An amazing multi-medicinal mushroom Invited International conference

    2016.11 

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    Event date: 2016.11

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:Nanjing   Country:China  

  • Two phenolic compounds from chloroform extracts of Syzygium polycephalum MIQ. stem bark (Myrtaceae) Invited International conference

    Shimizu K, Tukiran, Andika Pramdya Wardana, Nurul Hidayati

    The 1st International Joint Conference on Science and Technology (IJCST)  2016.10 

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    Event date: 2016.10

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Indonesia  

  • Triterpenoids: Clue for Understanding Multi-Medicinal effects of Ganoderma mushroom Invited International conference

    Shimizu K

    2016 International Conference on Ganoderma Research  2016.10 

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    Event date: 2016.10

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Viet Nam  

  • 抗ganoderic acid A モノクロナール抗体を用いた免疫クロマトグラフィーの確立

    清水邦義, 橘川奈生, 坂元政一, 河野聡亨, 田中宏幸, 森本聡

    第63回日本生薬学会  2016.9 

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    Event date: 2016.9

    Language:Japanese  

    Country:Japan  

  • スギの無垢材を内装に用いた建物内におけるヒト滞在時の調湿作用の研究

    本傳晃義, 奥田拓, 羽賀栄理子, 中島大輔, 鷲岡ゆき

    第66回日本木材学会大会  2016.9 

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    Event date: 2016.9

    Language:Japanese  

    Country:Japan  

  • New Secondary Metabolites From Ganoderma lingzhi International conference

    Shimizu Kuniyoshi, Yhiya M. Amen, Qinchang Zhu, Hai-Bang Tran, Satoru Kaifuchi, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Amira Mira

    InternationaSymposium on Natural Products for the future 2016 (ISNPF2016)  2016.9 

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    Event date: 2016.9

    Language:English  

    Country:Iceland  

  • Multi-functional effects of triterpenoids isolated from Ganoderma mushroom Invited International conference

    Shimizu K

    The First Chinese Lingzhi Conference  2015.8 

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    Event date: 2016.8

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:China  

  • Nepalese Wild Mushrooms: A Treasure Trove of Various Biological Activities International conference

    Shimizu K, Sonam Tamrakar, Hai Bang Tran, Marina Nishida, Satoru Kaifuchi, Hiroto Suhara, Katsumi Doi, Katsuya Fukami, Gopal Prasad Parajuli

    19th International Society for Mushroom Science (ISMS) Congress, Muziekgebouw aan het IJ  2016.5 

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    Event date: 2016.5 - 2016.6

    Language:English  

    Country:Iceland  

  • The Multi-functional effects of triterpenpoids isolated from Ganoderma lingzhi Invited International conference

    Shimizu K

    The 55th Aniversary of National Institute of Medicinal Materials (NIMM) conference  2016.4 

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    Event date: 2016.4

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Viet Nam  

  • オリーブ搾油残渣中の抗アレルギー活性成分と、表皮角化細胞の細胞内カルシウムイオン濃度に影響を与える成分

    清水 邦義, 岸川明日香, 片倉 喜範

    第66回日本木材学会大会  2016.3 

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    Event date: 2016.3

    Language:Japanese  

    Country:Japan  

  • Methoxyflavones from Ganoderma lingzhi

    Yhiya Amen, Satoru Kaifuchi, Shimizu K

    2016.3 

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    Event date: 2016.3

    Language:English  

    Country:Japan  

  • 屋久島地杉の心材色に着目した抽出物の新規利用法探索

    中川 敏法, 川崎 勝也, 武田 光史, 藤本 登留, 清水 邦義

    第66回日本木材学会大会  2016.3 

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    Event date: 2016.3

    Language:Japanese  

    Country:Japan  

  • Bioactivity and Chemical Characterization of some Wild Mushrooms of Nepal

    Sonam TAMRAKAR, Hai Bang TRAN, Marina NISHIDA, Hiroto SUHARA, Katsumi DOI, Katsuya FUKAMI, Gopal Prasad PARAJULI, Shimizu K

    2016.3 

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    Event date: 2016.3

    Language:English  

    Country:Japan  

  • 徳島県産スギ無垢板材の商品化における乾燥方法の検討 -乾燥方法と木取り位置の組み合わせによる検討-

    三好悠, 亀井裕人, 佐々木隆雄, 三枝康弘, 和田善行, 湊俊司, 阪井彰一, 千里泰三, 奥田拓, 村野朋哉, 中川敏法, 清水 邦義, 藤本 登留

    第66回日本木材学会大会  2016.3 

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    Event date: 2016.3

    Language:Japanese  

    Country:Japan  

  • 乾燥処理が徳島県産実生スギ材の抽出成分に与える影響

    奥田拓, 三好悠, 亀井裕人, 佐々木隆雄, 三枝康弘, 和田善行, 湊俊司, 阪井彰一, 千里泰三, 中川敏法, 藤本 登留, 清水 邦義

    第66回日本木材学会大会  2016.3 

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    Event date: 2016.3

    Language:Japanese  

    Country:Japan  

  • The Biological Activity of Ethanol Extract of Olive Milled Waste - Anti-allergic effect on RBL-2H3 and Stimulating effect on intracellular concentration of calcium ion in HaCaT International conference

    Kishikawa A, Yoshinori Katakura, Shimizu K

    Keystone Symposia: B5: Immunity in Skin Development, Homeostasis and Disease  2016.3 

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    Event date: 2016.2 - 2016.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • ガンマ線照射と電子線照射の脂質への影響の比較

    南 育子, 中川 敏法, 海渕 覚, 岸川 明日香, 堀場 大生, 大貫 宏一郎, 清水 邦義, 等々力 節子

    第51回 日本食品照射研究協議会  2015.11 

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    Event date: 2015.11 - 2015.10

    Language:Japanese  

    Country:Japan  

  • Differences in human physiological and psychological response: volatility and humidity conditioning effects caused by different wooden environments Invited International conference

    Shimizu K

    International Symposium on Frontier Researches in Sustainable Humanosphere 2015  2015.11 

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    Event date: 2015.11

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Japan  

    November 16th-17th, 2015

  • スギ(Cryptomeria japonica)の部位別抽出成分の生理活性探索

    清水 邦義, 堀場 大生, Ahmed Ashou, 中川敏法, 朱 欽昌, 小藤田 久義, 渡辺敦史

    第22回木材学会九州支部  2015.10 

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    Event date: 2015.10

    Language:Japanese  

    Country:Japan  

  • 木質空間に使用される素材の違いが室内の各種環境要素に及ぼす影響 -雨季の物理・化学的環境要素に着目した検討-

    奥田 拓, 鷲岡ゆき, 長池淳, 吉村友里, 井隼経子, 藤田 弘毅, 川﨑 章惠, 佐藤 宣子, 藤本 登留, 清水 邦義, 岡本 剛, 山田祐樹, 永野 純, 石川洋哉, 大貫宏一郎, 井上伸史, 渡邉雄一郎, 嶋津久憲, 安成信次

    第22回木材学会九州支部  2015.10 

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    Event date: 2015.10

    Language:Japanese  

    Country:Japan  

  • 屋久島地杉抽出成分の機能性探索抗菌活性

    中川敏法, 川崎勝也, 武田光史, 藤本 登留, 清水 邦義

    第22回木材学会九州支部  2015.10 

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    Event date: 2015.10

    Language:Japanese  

    Country:Japan  

  • Investigation for target protein uf ursolic acid with inhibitory activity on osteoclast differentiation International conference

    Tan H, Shimizu K

    ISPSA (Inaugural Symposium of the Phytochemical Society of Asia) 2015  2015.8 

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    Event date: 2015.8 - 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • In vivo and In vitro Hepatoprotective Activities of The Methanol Extract of Angelica shikokiana and Its Major Coumarin: Isoepoxypteryxin Against Hepacocellular Carcinoma International conference

    Mira A, Elshebiny N, Shebl A, Tran HB

    ISPSA (Inaugural Symposium of the Phytochemical Society of Asia) 2015  2015.8 

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    Event date: 2015.8 - 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

    ISPSA (Inaugural Symposium of the Phytochemical Society of Asia) 2015
    August 30th -

  • Biotransformation of Isoepoxypteryxin by Cordyceps sineneis through a Novel Microbial pathway and Improved Biological Activities International conference

    Amira M, Wael Alkhiary, Zhu Q, Nakagawa T, Tran H B, Shimizu K

    ISPSA (Inaugural Symposium of the Phytochemical Society of Asia) 2015  2015.8 

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    Event date: 2015.8 - 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Differences in physiological and psychological response to human,volatile and humidity conditioning effect caused by different wooden environment Invited International conference

    Shimizu K

    Integration of Psychology, Physiology, Education, and Policy For the Forest Healing  2015.7 

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    Event date: 2015.7

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Korea, Republic of  

  • Investigation of the Antioxidant Activities of the Wild Mushrooms of Nepal

    Sonam Tamrakar, Marina Nishida, Hiroto Suhara

    2015.3 

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    Event date: 2015.3 - 2016.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • スギ精油の香りに対するヒトの生理心理応答調査

    山邊結子, 中川敏法, 吉村友里, 長池淳, 福元菜穂子, 稲上誠, 光藤崇子, 須原弘登, 石川洋哉, 大貫宏一郎, 岡本剛, 清水 邦義

    第65回日本木材学会  2015.3 

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    Event date: 2015.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 空間嗜好性に着目した異なる木質空間における心理評価の違い

    清水 邦義, 長池淳, 松本清, 山本篤, 吉村友里, 稲上誠, 福元菜穂子, 中川敏法、, 藤田 弘毅, 藤本 登留, 佐藤 宣子, 川﨑 章惠, 岡本 剛, 永野 純, 光藤崇子, 石川洋哉, 大貫宏一郎, 井上伸史, 渡辺雄一郎, 嶋津久憲

    日本木材学会  2015.3 

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    Event date: 2015.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • スギ精油の香りに対するヒトの生理心理応答調査

    山邉結子, 松本 清, 山本 篤, 中川敏法, 光藤崇子, 須原弘登, 石川洋哉, 大貫宏一朗, 岡本 剛, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • Electrophysiological Characterization of Wooden Environment during Sleep

    Eka Permana K, Okamoto T, Yamada Y, Nagano J, Matsumoto S, Yamamoto A, Yamabe Y, Nakagawa T, Terui K, Fujita K, Kawasaki A, Sato N, Fujimoto N, Shimizu K, Mitsudo T, Nakashima T, Ishikawa H, Ohnuki K, Watanabe Y, Shimazu H

    2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Country:Japan  

  • モウソウチク抽出成分のアトピー性皮膚炎緩和効果の検証-黄色ブドウ球菌の増殖抑制とダニ抗原特異的IgE産生抑制-

    森 康浩, 岩元 彬, 田中明信, 永田敏郎, 清水 邦義, 川原浩治

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • ネパール産野生キノコに含まれる機能性成分の探索

    西田麻理奈, Tran Hai-Ban, 須原弘登, 土居克美, 深見克哉, Gopal Prasad Parajuli, 渡辺和夫, Mahesh Kumar Adhikari, Hira Kaji Manandhar, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • 屋久島に自生する杉(地杉)の生理活性に着目したカスケード的利用法の探索

    中川敏法, 岸川明日香, 石川洋哉, 大貫宏一郎, 柿野賢一, 堀内直哉, 篠塚宏明, 内藤輝美, 松本毅史, 南沢典子, 谷田貝光克, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • ファイトレメディエーションを指向した白色腐朽菌 Phlebia brevispora由来シトクロムP450遺伝子導入タバコ培養細胞の調製ならびに物質変換能評価

    豊田望美, 岡本早悠里, 重藤潤, 堤祐司, 其木茂則, 近藤隆一郎, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • スギ(Cryptomeria japonica)の部位別網羅的新規機能性探索

    堀場大生, 永田敏郎, Tran Hai-Ban, 渡辺敦史, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • Osteoclast Differentiation Inhibitors from Loquat Leaves (Eriobotrya japonica): Structure Activity Relationship

    2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Country:Japan  

  • 木質空間の快適性に関する脳科学的定量化

    清水 邦義, 岡本剛, 山田祐樹, 永野純, 松本清, 山本篤, 山邊結子, 中川敏法, 照井佳世, 藤田弘毅, 川﨑章惠, 佐藤宣子, 藤本登留, 光藤崇子, 石川洋哉, 大貫宏一郎, 中島大輔, 渡邉雄一郎, 嶋津久憲, 安成信次

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • 霊芝(Ganoderma lingzhi)の抗がん活性発現メカニズムの解明~Tubulin重合に与える影響解析~

    河野俊享, 澤井 健, トランハイバン, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • オリーブ(Olea europaea)各部位の生理活性の探索

    岸川明日香, 永田敏郎, 小浜友紀子, 相浦正文, 塚本敏郎, 中山良一, 安田みどり, 石川洋哉, 清水 邦義

    第64回 日本木材学会  2014.3 

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    Event date: 2014.3

    Language:Japanese  

    Venue:愛媛大学   Country:Japan  

  • Restorative effect of wooden materials on electrophysiological responses in humans International conference

    S. Matsumoto, T. Okamoto, A. Yamamoto, K. Shimizu

    Society for Neuroscience 2013  2013.11 

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    Event date: 2013.11

    Language:English  

    Country:United States  

  • Molecular target of triterpenoid with anticancer activity isolated from medicinal mushroom, Ganoderma lingzhi Invited International conference

    K. Shimizu (Keynote speaker)

    The Fifth International Symposium of Indonesian Wood Research Society  2013.11 

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    Event date: 2013.11

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Indonesia  

  • Synthesis and anti-proliferative activity of some oleanolic acid derivatives as potent topoisomerase inhibitors International conference

    A. Ashour, S. EI Sharkawy, M. Amer, K. Shimizu

    The Fifth International Symposium of Indonesian Wood Research Society  2013.11 

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    Event date: 2013.11

    Language:English  

    Country:Indonesia  

  • Utilization of Biomass (wood, mushroom etc) by Focusing on Their Biological Activities

    K. Shimizu

    EUIJ-Kyushu 3rd Annual International Conference  2013.11 

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    Event date: 2013.11

    Language:English  

    Country:Japan  

  • 健常成人女性の不定愁訴と身体活動量との関連

    栫 ちか子, 長野 真弓, 清水 邦義, 大貫 宏一郎

    第63回日本木材学会抽出成分利用研究会  2013.9 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:日本教育会館(東京)   Country:Japan  

  • Investigation on the biologically active compounds from Nepal’s mushroom ~Antioxidant and ACE inhibition~

    清水 邦義

    こうする!生物多様性条約と国際共同研究 九大・ネパールプロジェクトを事例として  2013.2 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:国際ホール(九州大学箱崎キャンパス)   Country:Japan  

  • トマトの部位別におけるリパーゼ阻害活性の検討

    宮崎明日香, 室井由起子, 清水邦義, 大貫宏一郎

    第60回日本栄養改善学会学術総会  2013.9 

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    Event date: 2013.9

    Language:Japanese  

    Venue:神戸国際会議場(口頭発表)   Country:Japan  

  • 成熟トマト・未成熟トマトの機能性評価

    室井由起子, 宮柱明日香, 清水邦義, 大貫宏一郎

    第60回日本栄養改善学会学術総会  2013.9 

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    Event date: 2013.9

    Language:Japanese  

    Venue:神戸国際会議場(口頭発表)   Country:Japan  

  • Hypotentive effects of Reishi (Ganoderma lingzhi)'s auto-digested extract ant it's potent peptides for the inhibition of Angiotensin-Converting Enzyme

    T. H. Bang, H. Ito, K. Igami, T. Miyazaki, R. Kondo, K. Shimizu

    2013.9 

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    Event date: 2013.9

    Language:Japanese  

    Country:Japan  

  • ヤマブシタケ(Hericium erinaceum)の行動リズムに与える影響

    平木絵理, 古田祥子, 佐藤大吾, 安尾しのぶ, 大貫宏一郎, 近藤隆一郎, 清水邦義

    日本きのこ学会 第17回大会  2013.9 

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    Event date: 2013.9

    Language:Japanese  

    Venue:県立広島大学広島キャンパス(口頭発表)   Country:Japan  

  • Aldose reductase inhibitory effect of Garcinia mangostana constituents

    Fatmawatia S, Shimizu K, Ersam T

    2013.9 

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    Event date: 2013.9

    Language:English  

    Country:Japan  

  • 天然・乾燥材と新建材の調温・調湿機能比較 ―寝室環境の経時的変化から―

    山本篤, 松本清, 山邊結子, 福田竜大, 藤田弘毅, 川﨑章惠, 佐藤宣子, 清水 邦義, 藤本登留, 岡本剛, 山田祐樹, 永野純, 光藤崇子, 石川洋哉, 大貫宏一郎, 中島大輔, 安成信次, 嶋津久憲, 渡邉雄一郎

    第20回日本木材学会九州支部大会  2013.9 

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    Event date: 2013.9

    Language:Japanese  

    Venue:九州大学 箱崎キャンパス   Country:Japan  

  • Corncobs as a Potential Source of Functional Chemicals

    Ashoura A, El-Sharkawy S, Amer M, Marzouk A, Kondo R, Shimizu K

    2013.9 

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    Event date: 2013.9

    Language:English  

    Country:Japan  

  • Osteoclast Differentiation Inhibitors from Loquat Leaves (Eriobotrya japonica): Structure Activity Relationship

    Tan H, Shimizu K

    2013.9 

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    Event date: 2013.9

    Language:English  

    Country:Japan  

  • 森林バイオマス高度利用のための鍵物質「抽出成分」 ~セルロース・リグニン以外の成分をいかに利用するか?~

    清水 邦義

    第37回九州紙パルプ研究会  2013.5 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:九州大学五十周年祈念講堂四階大会議室   Country:Japan  

  • アロマの効用~元気になる香り、癒される香り~

    清水 邦義

    第23回西日本食品産業創造展  2013.5 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:マリンメッセ福岡   Country:Japan  

  • 嗅覚九州プロジェクトの紹介」~医農理工文連携による「におい」の最先端総合研究~ Invited

    第63回日本木材学会抽出成分利用研究会  2013.3 

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    Event date: 2013.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岩手大学(盛岡市)   Country:Japan  

  • Molecular target of biologically active triterpenoid isolated from medicinal mushroom, Ganoderma lucidum Invited International conference

    K. SHIMIZU

    VII International Symposium on Natural Products Chemistry and its Applications (VIIISNPCA 2012)  2012.11 

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    Event date: 2012.11

    Presentation type:Oral presentation (invited, special)  

    Country:Chile  

  • 『天然由来の機能可能性を探る~人材育成と同じ。良い点を見つけて伸ばす~』

    清水 邦義

    第69回KDRIイブニングセミナー  2012.10 

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    Event date: 2012.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:熊本大学連携インキュベータ   Country:Japan  

  • タモギタケ子実体のメラニン生成促進成分

    孟天暁、清水邦義、大賀祥治、近藤隆一郎

    第16回日本きのこ学会  2012.9 

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    Event date: 2012.9

    Presentation type:Oral presentation (general)  

    Venue:東京都   Country:Japan  

  • タモギタケ子実体のメラニン生成促進成分

    孟天暁, 清水邦義, 大賀祥治, 近藤隆一郎

    第16回日本きのこ学会 2012年9月6-7日 東京都(口頭発表)  2012.9 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京都   Country:Japan  

  • Utilization of forest bio-resources (wood, mushroom etc) focusing on their biological activities International conference

    JBEI (Joint BioEnergy Institute)  2012.8 

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    Event date: 2012.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • タモギタケ子実体の生理活性成分

    K. Shimizu, 孟 天暁

    第19回日本木材学会九州支部大会 2012年8月24-25 宮崎市(口頭発表)  2012.8 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:宮崎市(口頭発表)   Country:Japan  

  • The Inhibitory Effect of Loquat Leaves (Eriobotrya japonica) on Ovariectomy-induced Bone Loss and Osteoclast Differentiation

    K. Shimizu, T. Hui

    2012.8 

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    Event date: 2012.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • タモギタケ子実体の生理活性成分

    孟天暁、清水邦義、近藤隆一郎

    第19回日本木材学会九州支部大会  2012.8 

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    Event date: 2012.8

    Presentation type:Oral presentation (general)  

    Venue:宮崎大学(宮崎市)   Country:Japan  

  • The inhibitory effect of loquat leaves (Eriobotrya japonica) on ovariectomy-induced bone loss and osteoclast differentiation

    T. Hui, S. Furuta, T. Nagata, T. Akasaka, B. Shirouchi, M. Sato, K. Shimizu, R. Kondo

    2012.8 

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    Event date: 2012.8

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • 『糸島天然素材(農林・海産物)のライブラリー化と有用機能探査』

    清水 邦義

    糸島市九州大学連携研究助成金 第2回研究発表会  2012.7 

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    Event date: 2012.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:九州大学 伊都キャンパス 総合学習プラザ   Country:Japan  

  • 『バイオマス資源の有効活用~樹皮・タマネギ皮等を活用した美白・抗酸化・消臭商品の開発~』

    清水 邦義

    シーズ発表会~大学研究者によるノウハウ・技術の発表~  2012.6 

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    Event date: 2012.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:博多座・西銀ビル13階   Country:Japan  

  • 『平成23年度事業化案件発掘・支援事業成果報告』

    清水 邦義

    九州地域バイオベンチャーフォーラム2012  2012.5 

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    Event date: 2012.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:熊本ホテルキャッスル2階   Country:Japan  

  • 『アロマの効用~元気になる香り、癒される香り~』

    清水 邦義

    第22回西日本食品産業創造展  2012.5 

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    Event date: 2012.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:マリンメッセ福岡   Country:Japan  

  • 『「噂を科学する」 ~身近な天然資源を生かすヒント~』

    清水 邦義

    平成23年度【RIST】「植物工場」第2回技術検討会 拡大セミナー  2012.3 

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    Event date: 2012.3

    Presentation type:Oral presentation (general)  

    Venue:熊本県産業技術センター大会議室   Country:Japan  

  • ヤマブシタケの卵巣摘出マウスにおける抗肥満効果

    古田 祥子、佐藤 崇雄、佐藤 大吾、大貫宏一郎、赤坂泰輝、城内 文吾、佐藤 匡央、清水 邦義、近藤 隆一郎

    第62回日本木材学会  2012.3 

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    Event date: 2012.3

    Presentation type:Oral presentation (general)  

    Venue:北海道大学農学部(札幌市)   Country:Japan  

  • Ganoderic acid DMの生理活性発現機構解析

    清水邦義、田中明信、劉潔、忍和歌子、近藤隆一郎

    第62回日本木材学会  2012.3 

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    Event date: 2012.3

    Presentation type:Oral presentation (general)  

    Venue:北海道大学農学部(札幌市   Country:Japan  

  • モウソウチク(Phyllostachys pubescens)のタケノコの皮に含まれる生理活性物質の探索

    田中明信、清水邦義、近藤隆一郎

    第62回日本木材学会  2012.3 

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    Event date: 2012.3

    Presentation type:Oral presentation (general)  

    Venue:北海道大学農学部(札幌市)   Country:Japan  

  • 言い伝えを科学する

    清水 邦義

    キーパーソン@「九州の食」プレステージ  2012.1 

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    Event date: 2012.1

    Presentation type:Oral presentation (general)  

    Venue:福岡合同庁舎本館5階中会議室A・B   Country:Japan  

  • Antioxidantive of Eleutherol from leaves of Tahongai (Klienhovia hospita) International conference

    E. T. Arung, I. W. Kusuma, Y. U. Kim, K. Shimizu, R. Kondo

    The 3rd International Symposium of Indonesian Wood Research Society  2011.11 

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    Event date: 2011.11

    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Anti-androgenic activity of Ganoderma lucidum Invited International conference

    K. Shimizu

    National Symposium on Natural Products Chemistry XIX  2011.10 

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    Event date: 2011.10

    Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • ヤマブシタケによる高脂肪食飼育OVXマウスによる体脂肪減少効果

    古田祥子、佐藤大吾、赤坂泰輝、城内文吾、佐藤匡央、大貫宏一郎、清水邦義、近藤隆一郎

    第15回日本きのこ学会  2011.9 

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    Event date: 2011.9

    Presentation type:Oral presentation (general)  

    Venue:信州大学農学部   Country:Japan  

  • タモギタケ子実体の抗菌活性成分

    孟天暁、石川洋哉、清水邦義、大賀祥治、近藤隆一郎

    第15回日本きのこ学会  2011.9 

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    Event date: 2011.9

    Presentation type:Oral presentation (general)  

    Venue:信州大学農学部   Country:Japan  

  • 霊芝由来機能性トリテルペノイドの標的分子の探索

    清水邦義、劉潔、近藤隆一郎

    第15回日本きのこ学会  2011.9 

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    Event date: 2011.9

    Presentation type:Oral presentation (general)  

    Venue:信州大学農学部   Country:Japan  

  • Development of evidence-based aroma: the effect of natural volatiles on task efficiency and psychophysiological response during the visual task Invited International conference

    K. Shimizu

    The 3rd East Asian International Symposium on National Resources for medicine  2011.8 

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    Event date: 2011.8

    Presentation type:Oral presentation (invited, special)  

    Country:Korea, Republic of  

  • モウソウチク(Phyllostachys pubescens)のタケノコの皮に含まれる抗菌活性物質の探索

    田中明信、金孝貞、小田正二郎、清水邦義、近藤隆一郎

    第18回日本木材学会九州支部大会  2011.8 

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    Event date: 2011.8 - 2011.3

    Presentation type:Oral presentation (general)  

    Venue:鹿児島大学   Country:Japan  

  • 植物の揮発成分提示による視覚作業時の作業効率および生理・心理応答へ与える影響

    松原恵理、清水邦義、近藤隆一郎

    第18回日本木材学会九州支部大会  2011.8 

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    Event date: 2011.8 - 2011.3

    Presentation type:Oral presentation (general)  

    Venue:鹿児島大学   Country:Japan  

  • (-)-酢酸ボルニル吸入が視覚作業時の作業効率および自律神経活動に与える影響

    松原恵理、大貫宏一郎、清水邦義、近藤隆一郎

    第61回日本木材学会  2011.3 

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    Event date: 2011.3

    Presentation type:Oral presentation (general)  

    Venue:京都大学   Country:Japan  

  • Ganoderic acid DMの標的分子の探索

    清水邦義、劉潔、近藤隆一郎

    第61回日本木材学会  2011.3 

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    Event date: 2011.3

    Presentation type:Oral presentation (general)  

    Venue:京都大学   Country:Japan  

  • Isoprenylated Flavonoids from wood of Artocarpus heterophyllus: cytotoxicity, structural criteria and mechanism in cancer cells

    E. T. Arung, B. Dani, Y. A. Handoko, F. Sandra, K. Shimizu, R. Kondo

    2010.8 

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    Event date: 2010.8

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • Effects of hydrophobic side chain in cardols and anacardic acids on tyrosinase International conference

    K. Shimizu, I. Kubo

    BIT's Inaugural Symposium on Enzymes & Biocatalysis  2010.4 

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    Event date: 2010.4

    Presentation type:Oral presentation (general)  

    Country:China  

  • エリンギ抽出物の破骨細胞分化抑制効果

    横山 聡、清水 邦義、近藤 隆一郎

    第60回日本木材学会  2010.3 

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    Event date: 2010.3

    Country:Japan  

  • スギ樹皮抽出物からの5α-reductase阻害物質の探索

    中本理、清水邦義、近藤隆一郎

    第60回日本木材学会  2010.3 

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    Event date: 2010.3

    Venue:宮崎県宮崎市松山   Country:Japan  

  • Aldose reductase inhibitors of Ganoderma lucidum

    S. Fatmawati, K. Shimizu, R. Kondo

    2009.11 

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    Event date: 2009.11

    Country:Japan  

  • モミ(Abies sibirica)精油が精神負荷作業時の生理的変化に及ぼす効果

    松原恵理、清水邦義、大貫宏一郎、近藤隆一郎

    香料・テルペンおよび精油化学に関する討論会  2009.11 

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    Event date: 2009.11

    Venue:生駒市   Country:Japan  

  • インドネシア産ベチバー根によるVOCsおよびアンモニアの低減効果

    松原恵理、小山太、吉田絵美、木下玲子、清水邦義、高木茂、宮本雅一、近藤隆一郎

    におい・かおり環境学会  2009.7 

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    Event date: 2009.7

    Presentation type:Oral presentation (general)  

    Venue:東京都   Country:Japan  

  • インドネシア産ベチバー根によるVOCsおよびアンモニアの低減効果

    松原恵理、小山太、吉田絵美、木下玲子、清水邦義、高木茂、宮本雅一、近藤隆一郎

    におい・かおり環境学会  2009.7 

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    Event date: 2009.7

    Venue:東京都   Country:Japan  

  • Gallic acid acts as a redox coupler in the tyrosinase-catalyzed oxidation of polyphenols

    K. Shimizu, I. Kubo

    2009.3 

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    Event date: 2009.3

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • インドネシア中部ジャワ州産11年生Acacia mangiumとAcacia auriculiformisの成長と木材性質

    長谷川益己、脇元理恵、吉田絵美、清水邦義、近藤隆一郎、Anthonius Widyatmoko, Arif Nirsatmanto, 白石進

    日本木材学会  2009.3 

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    Event date: 2009.3

    Presentation type:Oral presentation (general)  

    Venue:松本市   Country:Japan  

  • 「植物の多機能性に着目した多目的快適空間システムの開発」

    清水 邦義

    2009.2 

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    Event date: 2009.2

    Presentation type:Oral presentation (general)  

    Venue:ハイネスホテル久留米   Country:Japan  

  • The effects of triterpenoids isolated from Ganoderma lucidum on 5α-reductase, androgen receptor and LNCaP cells International conference

    2008.12 

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    Event date: 2008.12

    Presentation type:Oral presentation (general)  

    Country:Other  

  • The effects of artocarpin on melanogenesis and cytotoxicity International conference

    E. T. Arung, K. Yoshikawa, K. Shimizu, R. Kondo

    2008 'Shanghai International Symposium on pharmacy  2008.12 

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    Event date: 2008.12

    Presentation type:Oral presentation (general)  

    Country:Other  

  • Effects of scent compounds of "catinga de mulata" on mushroom tyrosinase International conference

    K. Shimizu, I. Kubo

    II Phytotherapeutics Conference of Mercosul, VI Meeting of the Latin American Phytochemistry Society  2008.12 

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    Event date: 2008.12

    Presentation type:Oral presentation (general)  

    Country:Brazil  

  • The prevention effect of ganoderic acid DM on prostate cancer International conference

    J. Liu, K. Shimizu, R. Kondo

    The 5th Meeting of East Asia for Collaboration on Edible Fungi  2008.9 

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    Event date: 2008.9

    Country:Other  

  • ベチバーを活用した消臭剤等の開発

    清水邦義、吉田絵美、近藤隆一郎

    2008.8 

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    Event date: 2008.8

    Presentation type:Oral presentation (general)  

    Venue:日田市   Country:Japan  

  • マンネンタケの抗男性ホルモン効果

    劉 潔、清水 邦義、近藤 隆一郎、金子 周平

    日本木材学会九州支部大会  2008.8 

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    Event date: 2008.8

    Presentation type:Oral presentation (general)  

    Venue:日田市   Country:Japan  

  • Aldose reductase inhibitors from Ganoderma lucidum International conference

    S. Fatmawati, J. Liu, K. Shimizu, R. Kondo

    7th Joint Meeting of the Association Francophone pour l'Enseignement et la Recherche en Pharmacognosie (AFERP), American Society of Pharmacognosy (ASP), Society for Medicinal Plant Research (GA), Phytochemical Society of Europe (PSE), and Society Italiana  2008.8 

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    Event date: 2008.8

    Presentation type:Oral presentation (general)  

    Country:Greece  

  • レーザーマイクロダイセクションによる微量組織でのリグニン生合成遺伝子転写解析およびリグニン分析

    田中奏、藤田弘毅、黒田健一、堤祐司、近藤隆一郎

    日本木材学会  2008.3 

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    Event date: 2008.3

    Presentation type:Oral presentation (general)  

    Venue:つくば市   Country:Japan  

  • マンネンタケの30%エタノール抽出物の前立腺肥大抑制効果

    劉潔、清水邦義、近藤隆一郎、小西史子、野田潔、隈本正一郎

    日本木材学会  2008.3 

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    Event date: 2008.3

    Presentation type:Oral presentation (general)  

    Venue:つくば市   Country:Japan  

  • スギ平角材のあらわし材に適した乾燥方法の検討

    松本勝男、藤本登留、臼田綾子、清水邦義、近藤隆一郎

    日本木材学会  2008.3 

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    Event date: 2008.3

    Presentation type:Oral presentation (general)  

    Country:Japan  

  • 機能性香りの量的質的成分分析ならびに生理・心理機能を指標とした評価システムの開発

    清水 邦義

    第12回次世代医療システム産業化フォーラム  2008.3 

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    Event date: 2008.3

    Venue:大阪商工会議所   Country:Japan  

  • 自然由来揮発成分のLOHAS指向豊かさ因子としての検証

    清水邦義、玉泉真弓、高田奈津美、村上千尋、河邉隆寛、小崎智照、石橋圭太、泉 龍介、水野谷 航、大貫宏一郎、近藤 隆一郎

    第5回「循環型住空間システムの構築」フォーラム -4年間の研究成果と最終年度に向けて-  2008.1 

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    Event date: 2008.1

    Venue:福岡ガーデンパレス   Country:Japan  

  • Anticoagulant active compounds of Angelica shikokiana International conference

    Amira Mira, Wael Alkhiary, Kuniyoshi Shimizu

    2015.3 

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    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 機能性増強を目指した担子菌によるモウソウチク(Phyllostachys pubescens)のバイオリファイナリー

    松尾タケル, 須原弘登, 主計高弘, 清水 邦義

    第21回日本木材学会九州支部大会 

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    Language:Japanese  

    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • Effect of compound X for working memory performance and amyloid-β protein in mice

    第87回日本薬理学会 

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    Language:English  

    Venue:東北大学百周年記念会館川内萩ホール (仙台市)   Country:Japan  

  • Effects of arbutin on mushroom tyrosinase and melanoma cells

    K. Shimizu, I. Kubo

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    Presentation type:Oral presentation (general)  

    Country:Japan  

  • 『マンネンタケ(Ganoderma lucidum)抽出物の骨密度低下メカニズムの解明』

    清水 邦義

    地域発技術シーズ発表会 ライフサイエンス(医療・医薬・食品) 

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    Venue:科学技術振興機構JSTホール(東京・市ヶ谷)   Country:Japan  

  • Phanerochaete chrysosporiumの産生するマンガンペルオキシダーゼ活性に影響を及ぼす物質について

    扇剛士、清水邦義、近藤隆一郎

    日本木材学会  2003.3 

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    Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

  • 熱帯産樹木パンノキ心材に含まれるアルトカルピンの美白メカニズムの解析

    清水邦義、吉川圭介、近藤隆一郎

    日本農芸化学会  2003.3 

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    Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 食用きのこ抽出物のエストロゲン様活性

    山中 麻衣子、清水 邦義、近藤隆一郎、筒井 元武、佐藤 郁夫、金子 周平

    日本木材学会  2003.3 

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    Venue:九州産業大学(福岡)   Country:Japan  

  • ナンキンハゼ(Sapium sebiferum)抽出物のメラニン生成抑制成分

    清水邦義、福永晶子、芦谷竜矢、近藤隆一郎

    日本農芸化学会  2004.3 

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    Presentation type:Oral presentation (general)  

    Venue:広島   Country:Japan  

  • マンネンタケからの5α-リダクターゼ阻害成分

    劉潔、清水邦義、金子周平、野田潔、小西史子、隈本正一郎、水海吉太郎、上田千恵、近藤隆一郎

    日本農芸化学大会  2004.3 

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    Presentation type:Oral presentation (general)  

    Venue:広島大学   Country:Japan  

  • 干しシイタケ抽出物のメラニン生成抑制効果

    安藤亮、清水邦義、冨田健次、藤本淳一、長畑哲二、近藤隆一郎

    日本菌学会  2004.5 

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    Presentation type:Oral presentation (general)  

    Venue:長崎   Country:Japan  

  • 干しシイタケ抽出物のメラニン生成抑制効果

    安藤亮、清水邦義、近藤隆一郎

    森林生態圏管理学(演習林)研究発表会  2004.6 

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    Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

  • 薬用・食用キノコからのアルドースレダクターゼ阻害作用を有する素材の探索

    青山かおり、田中弘次、神谷晋司、金子周平、清水邦義、近藤隆一郎

    日本キノコ学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:奈良   Country:Japan  

  • マンネンタケエタノール抽出物の骨密度改善効果

    宮本以智子、清水邦義、佐藤匡央、近藤隆一郎

    日本キノコ学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:奈良   Country:Japan  

  • 生物活性を指標とした高機能性バイオ新素材の開発(若手の会)

    清水邦義、橋田光、岸本崇夫

    日本木材学会若手の会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • 樹木タンニン類のメラニン生成抑制効果

    安藤亮、清水邦義、橋田光、牧野礼、大原誠資、近藤隆一郎

    日本木材学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • Tyrosinase inhibiroty activity of Artocarpus woods

    2004.8 

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    Presentation type:Oral presentation (general)  

    Country:Japan  

  • 樹木タンニン類の5α−リダクターゼ阻害活性

    劉潔、清水邦義、橋田光、牧野礼、大原誠資、近藤隆一郎

    日本木材学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • マンネンタケ抽出物の骨密度改善効果

    宮本以智子、清水邦義、佐藤匡央、近藤隆一郎

    日本木材学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • 薬用・食用キノコのアルドースレダクターゼ阻害活性

    清水邦義、神谷晋司、青山かおり、田中弘次、近藤隆一郎

    日本木材学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • エリンギ抽出物の骨密度改善効果

    玉泉真弓、山中麻衣子、佐藤郁夫、筒井元武、清水邦義、佐藤匡夫、近藤隆一郎

    日本木材学会  2004.8 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • 樹木タンニン類のB16メラノーマ細胞に及ぼす影響

    清水邦義、安藤亮、橋田光、牧野礼、大原誠資、近藤隆一郎

    日本木材学会  2005.3 

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    Presentation type:Oral presentation (general)  

    Venue:札幌   Country:Japan  

  • 樹木タンニン類のB16メラノーマ細胞における細胞増殖および色素形成に及ぼす影響

    清水邦義、安藤亮、橋田光、牧野 礼、大原 誠資、近藤隆一郎

    日本木材学会  2005.3 

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    Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  • 「住環境への応用を指向した森林の発する成分の人体への生理作用に対する影響の評価」

    清水邦義、石橋圭太

    第2回 フォーラム「循環型住空間システムの構築」(21世紀COEプログラム)  2005.4 

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    Presentation type:Oral presentation (general)  

    Venue:九州大学箱崎キャンパス 国際ホール   Country:Japan  

  • 「霊芝の多機能性生理活性〜高齢性ホルモン疾患予防・改善効果に着目して」 Invited

    清水邦義

    第54回 日本食品保蔵科学会大会シンポジウム  2005.6 

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    Presentation type:Oral presentation (general)  

    Venue:関東学院大学金沢八景キャンパス(神奈川県)  

  • 「樹木抽出成分の緩和・多機能性生理活性」 Invited

    清水邦義

    第4回 木材成分の化学的総合利用研究会  2005.6 

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    Presentation type:Oral presentation (general)  

    Venue:宮崎大学工学部(宮崎県)(  

  • Multifunctional biological activity of natural products from forest resources Invited International conference

    K. Shimizu

    8th Indonesian Wood Research Society (IWoRS)  2005.8 

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    Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • Anti-androgenic and estrogen-like activities of Ganoderma lucidum International conference

    K. Shimizu, J. Liu, I. Miyamoto, R. Kondo

    IWSS (The Sixth International Wood Science Symposium)  2005.8 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Bioactivity of water and ethanol extracts of Jackfruit (Artocarpus heterophyllus) wood, bark and leaves and its mistletoe (Macrosolen cochinchinensis) International conference

    N. Artani, I. Yudistira, M. Hanafi, E. T. Arung, K. Shimizu, R. Kondo

    IWSS (The Sixth International Wood Science Symposium)  2005.8 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Melanin biosynthesis inhibitory activity of chlorophorin and its derivative International conference

    E. T. Arung, K. Shimizu, R. Kondo

    IWSS (The Sixth International Wood Science Symposium)  2005.8 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Melanin biosynthesis inhibitory activity of chlorophorin and its derivative International conference

    E. T. Arung, K. Shimizu, R. Kondo

    8th Indonesian Wood Research Society (IWoRS)  2005.9 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Anti-androgenic and estrogen-like activities of Ganoderma lucidum International conference

    K. Shimizu, J. Liu, I. Miyamoto, R. Kondo

    8th Indonesian Wood Research Society (IWoRS)  2005.9 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • Multifunctional Biological Activity of Natural Products from Forest Resources Invited International conference

    K. Shimizu

    2005.9 

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    Presentation type:Oral presentation (general)  

    Country:Indonesia  

  • 「生物活性を指標とした高機能性バイオ新素材の開発」 Invited

    清水 邦義

    「江間忠木材・江間忠合板研究助成制度」助成プロジェクト発表会  2005.11 

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    Presentation type:Oral presentation (general)  

    Venue:新木場振興「新木場ホール」(東京)  

  • マンネンタケ(Ganoderma lucidum)エタノール抽出物による骨粗鬆症予防効果

    近藤隆一郎、宮本 以智子、清水 邦義、久木田敏夫

    第4回日本機能性食品医用学会総会  2005.12 

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    Venue:東京慈恵会医科大学(東京都)(   Country:Japan  

  • Effect of Isoprenoid-substituted Flavonoids Isolated from Artocarpus heterophyllus on Melanin Biosynthesis

    2006.8 

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    Presentation type:Oral presentation (general)  

    Country:Japan  

  • マンネンタケからの5α−リダクターゼ阻害成分

    劉 潔、清水邦義、近藤隆一郎

    日本木材学会  2006.8 

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    Presentation type:Oral presentation (general)  

    Venue:秋田市   Country:Japan  

  • Rhodococcus equiによるテストステロンから9α−水酸化ステロイドへの変換

    金 容雄、清水邦義、堤祐司、近藤隆一郎、Seung Ki Lee, Sang Sup Lee、Jaehong Han

    日本木材学会  2006.8 

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    Presentation type:Oral presentation (general)  

    Venue:秋田市   Country:Japan  

  • 霊芝抽出物の破骨細胞分化抑制活性

    塩野順、久木田明子、劉 潔、清水邦義、近藤隆一郎

    第57回日本木材学会  2007.8 

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    Venue:広島市   Country:Japan  

  • 『森林生物資源の多機能性生理活性~霊芝(マンネンタケ)の前立腺肥大症予防効果~』

    清水 邦義

    第57回日本木材学会  2007.8 

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    Venue:広島市   Country:Japan  

  • 『身近に役立つ森のはたらき』

    清水 邦義

    2007.9 

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    Venue:大川市   Country:Japan  

  • 『マンネンタケ(Ganoderma lucidum)抽出物の骨密度低下メカニズムの解明』

    清水 邦義

    JSTイノベーションプラザ福岡研究成果発表会  2007.10 

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    Venue:ホテルセントラーザ博多   Country:Japan  

  • マンネンタケの菌床びん栽培

    金子 周平、石川 景子、清水 邦義、劉 潔、近藤隆一郎、隈本正一郎、小西史子、水海 吉太郎

    日本キノコ学会  2007.11 

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    Country:Japan  

  • 霊芝中の生理活性物質を利用した男性排尿障害に対する特定保健用食品の開発:プラセボコントロール、用量設定比較試験

    野口正典、角間辰之、富安克郎、小西史子、隈本正一郎、清水邦義、近藤隆一郎、松岡啓

    第59回日本泌尿器科学会西日本総会  2007.11 

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    Country:Japan  

  • 『前立線肥大症予防・改善効果を有する霊芝を原料とした機能性食品の開発』

    清水 邦義

    アグリビジネス創出フェアin 九州  2007.11 

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    Venue:久留米リサーチセンタービル(展示場)   Country:Japan  

  • 『森林生物資源の多機能性生理活性~機能性「食」・「香り」~』

    清水 邦義

    先端セミナー  2007.12 

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    Venue:鳥取大学農学部   Country:Japan  

  • マングローブ林から採取したPhlebia acanthocystisの生物学的特性

    山邊結子, 早乙女梢, 中桐昭, 霜村典宏, 前川二太郎, 清水 邦義

    第57回日本菌学会  2013.6 

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    Language:Japanese  

    Venue:東京農業大学   Country:Japan  

  • 日本産Hypholoma fasciculare (ニガクリタケ)の分類学的再評価

    西田麻理奈, 早乙女梢, 長澤栄史, 中桐昭, 前川二太郎, 清水 邦義

    第57回日本菌学会  2013.6 

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    Venue:東京農業大学   Country:Japan  

  • N源およびFe源がマツタケ菌糸体生長および形態に与える影響

    田﨑徳也, 近藤隆一郎

    第57回日本菌学会  2013.6 

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    Venue:東京農業大学   Country:Japan  

  • 木質空間における生理心理応答:無垢材と新建材での比較

    清水 邦義, 松本清, 山本篤, 福田竜大, 山邊結子, 藤田弘毅, 川﨑章惠, 佐藤宣子, 藤本登留, 岡本剛, 山田祐樹, 永野純, 光藤崇子, 大貫宏一郎, 石川洋哉, 中島大輔, 安成信次, 嶋津久憲, 渡邉雄一郎

    第20回日本木材学会九州支部大会  2013.9 

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    Venue:九州大学 箱崎キャンパス   Country:Japan  

  • 緑の付加価値の高い新しい利活用法開発のヒント~人に及ぼす影響に着目して~

    清水 邦義

    第24回福岡県の緑を考える会  2013.9 

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    Language:Japanese  

    Venue:ホテルニュープラザ久留米(福岡県)   Country:Japan  

  • 天然素材の言い伝え・噂・スクリーニングを元とした実用化研究アプローチ~香りからポリフェノールまでを例として~』 グリーンケミカル・イノベーション~自然環境矯正共生型社会をめざす香りの研究開発を巡って~

    清水 邦義

    第14回アロマ・サイエンス・フォーラム2013  2013.10 

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    Language:Japanese  

    Venue:アルカディア市ヶ谷 (東京都)   Country:Japan  

  • 『多機能性キノコ“霊芝(Ganoderma lingzhi)”の更年期障害改善効果~エストロゲン様活性・骨密度低下抑制活性に着目して~』更年期から総合力を高めるために-予防から一歩進んだ健康戦略を考える-

    清水 邦義

    第1回日本サプリメント学会  2013.10 

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    Venue:帝京平成大学池袋キャンパス (東京都)   Country:Japan  

  • スギ精油の健康増進効果を切り口とした新規機能性の探索

    清水 邦義

    日本木材学会/江間忠研究助成プロジェクト発表会  2013.10 

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    Venue:東京大学弥生講堂 (東京都)   Country:Japan  

  • 国産杉を活用した住宅建築と産学連携プロジェクトの展開』 快適な住まいと環境~自然を活かし、自然と共に暮らす~

    清水 邦義

    第11回福岡女子大学産学官技術交流会  2013.11 

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    Venue:福岡女子大学 視聴覚室 (付属図書館1階)   Country:Japan  

  • 香りの空間~木のはたらき~

    清水 邦義

    屋久島地杉集い 木育セミナーin福岡  2014.1 

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    Venue:アクロス福岡2Fセミナー室2   Country:Japan  

  • 甘草各部位抽出物の有用機能性の探索

    清水 邦義

    玄海町・九州大学 薬用植物の総合研究プロジェクト(第二期) -薬用植物を活かした地域振興に向けて-  2014.2 

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    Venue:玄海町薬用植物栽培研究所研修室   Country:Japan  

  • 自然の個性をいかに活かすか?

    清水 邦義

    第一回九大Tech Forum  2014.2 

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    Venue:ホテル日航3F都久志の間   Country:Japan  

  • きのこの噂を科学する

    清水 邦義

    福岡きのこ友の会  2014.3 

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    Venue:福岡あいれふ10階講堂   Country:Japan  

  • 持続的国産材利用を目指した木の多面的機能解析

    清水 邦義

    共進化社会システム創成拠点フォーラム  2014.3 

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    Venue:TKP市ヶ谷カンファレンスセンター(東京都)   Country:Japan  

  • 持続的国産材利用を目指した木の多面的機能解析

    清水 邦義

    共進化社会システム創成拠点フォーラム  2014.3 

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    Venue:TKP市ヶ谷カンファレンスセンター(東京都)   Country:Japan  

  • 神経栄養効果と生体内活性構造に着目したヤマブシタケの精神疾患改善機構の解明

    平木絵里, 片倉喜範, 清水 邦義

    第65回日本木材学会  2014.3 

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    Venue:タワーホール船堀 東京   Country:Japan  

  • 天然素材の都市伝説を科学する~アロマ、キノコ・・・自然の知られざる力~

    清水 邦義

    サイエンスカフェ@ふくおか  2014.4 

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    Venue:TKP市ヶ谷カンファレンスセンター(東京都)   Country:Japan  

  • ヤマブシタケは骨格筋の核内受容体PPARδを活性化する

    水野谷航, 石井もも子, 清水 邦義, 永田敏郎, 平木絵里, 中村俊哉, 中村真子, 辰巳隆一, 池内義秀

    第68回日本栄養・食糧学会  2014.5 

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    Country:Japan  

  • Zn2+がマツタケ菌叢形態および代謝物プロファイルに与える影響

    田崎徳也, 清水 邦義, 近藤 隆一郎

    第58回日本菌学会  2014.6 

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    Country:Japan  

  • ネパール原産キノコエタノール抽出物の生理活性評価

    西田麻理奈, Tran Hai Bang, 須原弘登, 土居克実, 深見克哉, Gopal Prasad Parajuli, 渡辺和夫, Mahesh Kumar Adhikari, Hira Kaji Manandhar, 清水 邦義

    第58回日本菌学会  2014.6 

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    Venue:サイエンスヒルズこまつ(石川県)   Country:Japan  

  • 農林業の6次化とスマートコミュニティ

    清水 邦義

    九州エコフェア2014:再生エネルギー&スマートコミュニティ・スマートコミュニティ関連講演III  2014.6 

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    Venue:福岡国際センター   Country:Japan  

  • 糸島農林水産物高付加価値化を目指した有用機能探索

    清水 邦義

    糸島市九州大学連携研究助成金研究発表会(平成24年度助成分)  2014.7 

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    Venue:糸島市役所 本庁舎新館501会議室   Country:Japan  

  • 国産スギの抽出成分に着目した高度カスケード利用法~香りからポリフェノールまで~

    清水 邦義

    平成26年度木を活かす人材養成事業講座講演  2014.7 

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    Venue:徳島県 建設センター3F   Country:Japan  

  • ヌメリスギタケ抽出物に含まれる機能性成分の探索

    馬場純子, 清水 邦義

    日本きのこ学会第18回大会  2014.9 

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    Venue:京都大学 百周年時計台記念館(京都)   Country:Japan  

  • ネパール原生きのこ抽出物がメラニン生合成に与える影響

    西田麻理奈, Tran Hai Bang, 須原弘登, 土居 克実, 深見克哉, Gopal Prasad Parajuli, 渡辺和夫, Mahesh Kumar Adhikari, Hira Kaji Manandhar, 清水 邦義

    日本きのこ学会第18回大会  2014.9 

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    Venue:京都大学 百周年時計台記念館(京都)   Country:Japan  

  • 屋久杉(地杉)の精油および各種副産物における機能性探索

    中川敏法, 朱欽昌, 清水 邦義, 石川洋哉, 大貫宏一郎, 柿野賢一, 堀内直哉, 篠塚宏明, 内藤輝実, 松本毅史, 南沢典子, 谷田貝光克

    第21回日本木材学会九州支部大会  2014.9 

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    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • 屋久杉(地杉)の精油および各種副産物における機能性探索

    中川敏法, 朱欽昌, 清水 邦義, 石川洋哉, 大貫宏一郎, 柿野賢一, 堀内直哉, 篠塚宏明, 内藤輝実, 松本毅史, 南沢典子, 谷田貝光克

    第21回日本木材学会九州支部大会  2014.9 

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    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • 乾燥方法の異なる徳島すぎ人工乾燥材における加熱脱着GC-MS法を用いた揮発性成分分析

    吉村友里, 中川敏法, 清水 邦義, 藤本 登留, 石川洋哉, 大貫宏一郎, 網田克明, 橋本茂, 和田善行

    第21回日本木材学会九州支部大会  2014.9 

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    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • 「無垢材」と「新建材」を使った居住空間におけるヒトの生理心理学的分析

    長池淳, 松本清, 福田竜大, 山邊結子, 照井佳世, 吉村友里, 中川敏法, 藤田 弘毅, 川﨑 章惠, 佐藤 宣子, 藤本 登留, 清水 邦義, 岡本 剛, 山田 祐樹, 永野 純, Kurniawan Eka Pormane, 光藤崇子, 大貫宏一郎, 石川洋哉, 中島大輔

    第21回日本木材学会九州支部大会  2014.9 

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    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • スキンケアを指向したスギ(Cryptomeria japonica)の部位別機能性探索

    堀場大生, 中川敏法, 朱欽昌, 渡辺 敦史, 清水 邦義

    第21回日本木材学会九州支部大会  2014.9 

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    Venue:くまもと県民交流館パレア(熊本県)   Country:Japan  

  • ヤマブシタケHericium erinaceumの精神疾患改善機構

    平木絵里, 門岡桂史, 片倉喜範, 清水 邦義

    第61回日本生薬学会年会  2014.9 

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    Venue:福岡大学薬学部(福岡)   Country:Japan  

  • 日本の代表的な木の香気特性

    清水 邦義, 鳥谷涼, 長谷川登志夫, 藤原隆司

    第58回香料・テルペンおよび精油化学に関する討論会(TEAC2014)  2014.9 

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    Venue:和歌山大学   Country:Japan  

  • Inhibition Effect of Ganoderma Triterpenoids against Influenza Neuraminidase and Implications for Neuraminidase Inhibitor Design

    2014.12 

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    Country:Japan  

  • 植物香気成分の吸入が自律神経活動に及ぼす効果

    小川愛, 光永徹, 清水 邦義, 近藤 隆一郎, 其田桂子, 松原恵理

    第65回日本木材学会  2015.3 

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    Country:Japan  

▼display all

MISC

  • An Update on Antitumor Activity of Angelica Species

    Amira Mira, kuniyoshi shimizu

    Medicinal Plants - Recent Advances in Research and Development, pp 363-371   2016.10

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  • 森林生物資源の抽出成分の機能性に着目した研究展開

    清水 邦義

    生物資源第10巻2号   2016.8

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  • 特集にあたって―生物におけるにおい―

    清水 邦義

    におい・かおり環境学会誌 47巻1号1   2016.7

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  • 九州大学大学院農学研究院森林圏環境資源科学講座 清水グループ ありふれた自然素材を見捨てない、”よろず屋”的アプローチで、人に役立つ”才能”のエビデンスを探る

    清水 邦義

    2016.5

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  • ハーブティーの便通および体組成に対する効果

    後藤純平, 清水 邦義, 大貫 宏一郎, 佐藤大吾

    新薬と臨床   2016.5

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  • 木の家の健康を科学する実験

    清水 邦義

    安成工務店グループCSVレポート   2016.4

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  • 生理・心理応答解析から見えてきたヒトと「かすかな」においの関係とその応用

    鷲岡ゆき, 大貫 宏一郎, 清水 邦義

    におい・かおり環境学会誌   2016.1

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  • 霊芝の多機能性薬理効果に関する近年の科学的検証in press

    清水 邦義, 朱 欽昌, 吉村 友里, 海渕 覚, 桑原 李佳, 大貫 宏一郎

    FFIジャーナル   2016.1

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  • 天然素材の言い伝え・噂・スクリーニングを元にした実用化研究開発アプローチ~香りからポリフェノールまでを例として~

    清水 邦義

    2014.5

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  • かすかな香りの効用~香りの定性定量分析および生理心理評価を中心とした付加価値創造~

    清水 邦義, 松本 清, 大貫 宏一郎

    バイオサイエンスとインダストリー   2014.5

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  • 木質空間の特徴を生理心理応答から明らかにする試み ―無垢材と新建材の部屋で人の心身はどのような応答を示すか?―

    2013.4

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  • 「カリフォルニア大学とアマゾン川流域に滞在して」

    清水 邦義

    ニュースレター Vol. 63   2013.2

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  • インドネシアの未開発天然素材の多機能性・多様性に着目した高度利用

    清水 邦義

    2013.1

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  • Molecular Design of Soybean Lipoxygenase Inhibitors Based on Natural Products

    I. Kubo, T. J. Ha, K. Shimizu

    A Comprehensive Survey of International Soybean Research - Genetics, Physiology, Agronomy and Nitrogen Relationships, James E. Board (Ed.), ISBN: 978-953-51-0876-4, InTech, DOI: 10.5772/52703.   2013.1

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  • 天然素材の『噂を科学する』地域企業密着型研究

    清水 邦義

    産学連携ジャーナル 5月号   2012.5

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  • Antioxidant Activity of Anacardic Acids

    N. Masuoka, K. Shimizu, I. Kubo

    In: Antioxidants and Biocides from Latin American Plants; C.L. Cespedes, D.A. Sampietro, D.S. Seigler, Ed., CABI Publishing (UK)(2012)   2012.2

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  • Naturally Occurring Antifungal Agents and Their Modes of Action.

    I. Kubo, K. Shimizu, K. Fujita

    In : Fungicides Volume I; D. Dhanasekaran, N. Thajuddin, A. Panneerselvam, Ed., InTech - Open Access Publisher   2012.2

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  • MANICOBA, A quercetin rich Amazonian dish

    I. Kubo, K. Shimizu, K. Nihei

    In: Quercetin: Dietary Sources, Functions and Health Benefits- Nova Science Publishers, Inc.   2012.2

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Anti-Salmonella Agents from Tanacetum Balsamita, A Brazilian Medicinal Plant, and their Application

    I. Kubo, K. Fujita, K. Shimizu

    In: Antioxidants and Biocides from Latin American Plants; C.L. Cespedes, D.A. Sampietro, D.S. Seigler, Ed., CABI Publishing (UK)   2012.2

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  • Artocarpus Plants as a Potential Source of Skin Whitening Agents

    E. T. Arung, K. Shimizu, R. Kondo

    Natural Product Communications   2011.7

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  • ウッドサイエンス・ミキサーを振り返って(その2)

    清水 邦義、長谷川 益己、亀井 一郎

    木科学情報, 17巻2号28-30   2010.10

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  • パンノキ属樹木抽出物の多機能性~4位置換レゾルシノール構造を有するイソプレニル置換ポリフェノールの多機能性生理活性発現機構~

    清水邦義、エノスタンケアルング、近藤隆一郎

    2010.7

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  • ウッドサイエンス・ミキサーを振り返って(その1)

    清水 邦義、長谷川 益己、亀井 一郎

    木科学情報   2010.6

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  • Multifunctional Antioxidant Activities of Alkyl Gallates

    I. Kubo, N. Masuoka, T. J. Ha, K. Shimizu, K. Nihei

    The Open Bioactive Compounds Journal   2010.6

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  • Multifunctional Acne Control Agents

    I. Kubo, T. J. Ha, T. Nitoda, K. Shimizu, A. Kubo

    Current Topics in Phytochemistry   2008.6

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  • 超高齢化社会に向けて林産研究者が何をすべきか?〜霊芝(キノコ)の高齢性疾患(前立腺肥大症)予防・改善効果〜

    清水邦義 、劉 潔、近藤 隆一郎

    木科学情報   2005.1

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  • Tyrosinase and 5a-Reductase Inhibitory Components from Artocarpus incisus

    K. Shimizu

    Bull. Kyushu Univ. For.   2001.1

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  • Cupressaceae trees and their bioactivities.

    K. Shimizu, R. Kondo, K. Sakai

    Bull. Kyushu Univ. For.   2001.1

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  • 森林生物資源からの生理活性成分の探索

    清水邦義

    九州大学ベンチャービジネスラボラトリー 2000 年度 年報   2000.10

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  • Tyrosinase inhibitors from Artocarpus incisus.

    K. Shimizu, R. Kondo, K. Sakai

    Research Advances in Phytochemistry   2000.1

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  • 多機能性キノコ「霊芝」(Ganoderma lingzhi)の更年期症状改善効果

    清水 邦義, 河野 俊亨

    更年期と加齢のヘルスケア   1900

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  • 健康な毎日を送る木の家の7つの効果

    清水邦義

    建築知識ビルダーズ,No38,小冊子   2019.9

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  • ジャパン・コスメティックセンターとの化粧品プロジェクト 佐賀県産農産物の魅力を掘り起こすーコスメティック原料としての潜在能力

    清水邦義、中川敏法

    2019.7

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  • An LC-MS/MS-SRM Method for Simultaneous Quantification of Four Representative Organosulfur Compounds in Garlic Products

    Qinchang Zhu, Kenichi Kakino, Chika Nogami, Koichiro Ohnuki, Kuniyoshi Shimizu

    Food Analytical Methods   2016.12

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    DOI: 10.1007/s12161-016-0535-1

  • Antioxidative activities of 62 wild mushrooms from Nepal and the phenolic profile of some selected species

    Sonam Tamrakar, Hai Bang Tran, Marina Nishida, Satoru Kaifuchi, Hiroto Suhara, Katsumi Doi, Katsuya Fukami, Gopal Prasad Parajuli, Kuniyoshi Shimizu

    Journal of Natural Medicines   2016.10

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    DOI: 10.1007/s11418-016-1013-1

  • Improved Biological Activities of Isoepoxypteryxin by Biotransformation

    Amira Mira, Wael Alkhiary, Qinchang Zhu, Toshinori Nakagawa, Hai Bang Tran, Yhiya M. Amen, Kuniyoshi Shimizu

    Chemistry and Biodiversity   2016.10

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    DOI: 10.1002/cbdv.201600049

  • Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi

    Seiichi Sakamoto, Nao Kikkawa, Toshitaka Kohno, Kuniyoshi Shimizu, Hiroyuki Tanaka, Satoshi Morimoto

    Fitoterapia   2016.10

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    DOI: 10.1016/j.fitote.2016.08.016

  • Acetylcholine esterase inhibitors and melanin synthesis inhibitors from Salvia officinalis

    Amal Sallam, Amira Mira, Ahmed Ashour, Kuniyoshi Shimizu

    Phytomedicine   2016.9

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    DOI: 10.1016/j.phymed.2016.06.014

  • New cytotoxic lanostanoid triterpenes from Ganoderma lingzhi

    Yhiya M. Amen, Qinchang Zhu, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Kuniyoshi Shimizu

    Phytochemistry Letters   2016.9

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    DOI: 10.1016/j.phytol.2016.07.024

  • Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells

    Yhiya M. Amen, Qinchang Zhu, Hai Bang Tran, Mohamed S. Afifi, Ahmed F. Halim, Ahmed Ashour, Amira Mira, Kuniyoshi Shimizu

    Journal of Natural Medicines   2016.7

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    DOI: 10.1007/s11418-016-0976-2

  • Biological Activities of Oleanolic Acid Derivatives from Calendula officinalis Seeds

    Ahmed Zaki, Ahmed Ashour, Amira Mira, Asuka Kishikawa, Toshinori Nakagawa, Qinchang Zhu, Kuniyoshi Shimizu

    Phytotherapy Research   2016.5

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    DOI: 10.1002/ptr.5589

  • Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay

    Seiichi Sakamoto, Toshitaka Kohno, Kuniyoshi Shimizu, Hiroyuki Tanaka, Satoshi Morimoto

    Planta Medica   2016.5

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    DOI: 10.1055/s-0042-104202

  • Simultaneous determination of four vasoactive phytochemicals in different pharmaceutical preparations by a simple HPLC-DAD method

    Fawzia Ibrahim, Mohie Khaled Sharaf El-Din, Rania Nabih El-Shaheny, Asmaa Kamal El-Deen, Kuniyoshi Shimizu

    Analytical Methods   2016.2

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    DOI: 10.1039/c5ay03003j

  • Hericium erinaceus extracts alter behavioral rhythm in mice

    Shoko Furuta, Rika Kuwahara, Eri Hiraki, Koichiro Ohnuki, Shinobu Yasuo, Kuniyoshi Shimizu

    Biomedical Research   2016.1

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    DOI: 10.2220/biomedres.37.227

  • Multiple uses of Essential Oil and By-Products from Various Parts of the Yakushima Native Cedar (Cryptomeria Japonica)

    Toshinori Nakagawa, Qinchang Zhu, Hiroya Ishikawa, Koichiro Ohnuki, Kenichi Kakino, Naoya Horiuchi, Hiroaki Shinotsuka, Terumi Naito, Tsuyoshi Matsumoto, Noriko Minamisawa, Mitsuyoshi Yatagai, Kuniyoshi Shimizu

    Journal of Wood Chemistry and Technology   2016.1

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    DOI: 10.1080/02773813.2015.1057648

  • Methoxyflavones from New Lingzhi medicinal mushroom, Ganoderma lingzhi (agaricomycetes)

    Kuniyoshi Shimizu, Yhiya M. Amen, Satoru Kaifuchi

    International Journal of Medicinal Mushrooms   2016.1

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    DOI: 10.1615/IntJMedMushrooms.v18.i8.70

  • Anti-choline esterase activity of ceramides from the Red Sea marine sponge Mycale euplectellioides

    Reda Abdelhameed, Mohamed Saleh Elgawish, Amira Mira, Amany K. Ibrahim, Safwat A. Ahmed, Kuniyoshi Shimizu, Koji Yamada

    RSC Advances   2016

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    DOI: 10.1039/c5ra26424c

  • 生理・心理応答解析から見えてきたヒトと「かすかな」においの関係とその応用

    におい・かおり環境学会誌   2016

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  • 森林資源科学の抽出成分の機能性に着目した研究展開

    生物資源   2016

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  • Biological activities of extracts from different parts of cryptomeria japonica

    Hiroki Horiba, Toshinori Nakagawa, Qinchang Zhu, Ahmed Ashour, Atsushi Watanabe, Kuniyoshi Shimizu

    Natural Product Communications   2016

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  • Antioxidant activity of Moringa oleifera extracts

    Wiwit Denny Fitriana, Taslim Ersam, Kuniyoshi Shimizu, Sri Fatmawati

    Indonesian Journal of Chemistry   2016

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    DOI: 10.22146/ijc.1148

  • Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design

    Qinchang Zhu, Tran Hai Bang, Koichiro Ohnuki, Takashi Sawai, Ken Sawai, Kuniyoshi Shimizu

    Scientific Reports   2015.8

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    DOI: 10.1038/srep13194

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Industrial property rights

Patent   Number of applications: 61   Number of registrations: 13
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Professional Memberships

  • 日本農芸化学会

  • 日本生薬学会