トピックス賞

2015年3月   日本農芸化学会   Asian Microbiome Project phase 2: アジア人の腸内細菌叢の加齢に伴う変化

森永賞

2008年6月   森永奉仕会   乳児アレルギー早期予知のための腸内フローラ解析技術の開拓

ポスター賞

2005年8月   アメリカ微生物学会   Screening for quorum sensing inhibitors targeting fsr regulatory system

論文賞

2004年10月   日本生物工学会   Effect of Heterologous Expression of Molecular Chaperone DnaK from Tetragenococcus halophilus on Salinity Adaptation of Escherichia coli

農芸化学奨励賞

1999年4月   日本農芸化学会   腸球菌の生フェロモンシグナリングに関する生物有機化学的・分子生物学的研究

Dense tracking of the dynamics of the microbial community and chemicals constituents in spontaneous wheat sourdough during two months of backslopping. 査読

Mugihito Oshiro, Rie Momoda, Masaru Tanaka, Takeshi Zendo, Jiro Nakayama

Journal of bioscience and bioengineering   128 ( 2 )   170 - 176   2019年8月

Urban Diets Linked to Gut Microbiome and Metabolome Alterations in Children: A Comparative Cross-sectional Study in Thailand 査読 国際誌

Juma M. Kisuse, Orawan La-ongkham, Massalin Nakphaichit, Phatthanaphong Therdtatha, Rie Momoda, Masaru Tanaka, Shinji Fukuda, Siam Popluechai, Kongkiat Kespechara, Kenji Sonomoto, Yuan-Kun Lee, Sunee Nitisinprasert and Jiro Nakayama

Front. Microbiol.   2018年8月

Gut dysbiosis associated with hepatitis C virus infection 査読 国際誌

Inoue T, Nakayama J, Moriya K, Kawaratani H, Momoda R, Ito K, Iio E, Nojiri S, Fujiwara K, Yoneda M, Yoshiji H, Tanaka Y

Clin Infect Dis   67 ( 6 )   869 - 877   2018年5月

Metabolic dependent and independent pH-drop shuts down VirSR quorum sensing in Clostridium perfringens. 査読

Keika Adachi, Kaori Ohtani, Michio Kawano, Ravindra Pal Singh, Basit Yousuf, Kenji Sonomoto, Tohru Shimizu, Jiro Nakayama

Journal of bioscience and bioengineering   125 ( 5 )   525 - 531   2018年5月

Development of the gut microbiota in infancy and its impact on health in later life. 招待 査読 国際誌

Masaru Tanaka, Jiro Nakayama

Allergology international : official journal of the Japanese Society of Allergology   66 ( 4 )   515 - 522   2017年10月

Signatures in the gut microbiota of Japanese infants who developed food allergies in early childhood. 査読 国際誌

Masaru Tanaka, Yuki Korenori, Masakazu Washio, Takako Kobayashi, Rie Momoda, Chikako Kiyohara, Aki Kuroda, Yuka Saito, Kenji Sonomoto, Jiro Nakayama

FEMS microbiology ecology   93 ( 8 )   1 - 11   2017年8月

Impact of westernized diet on gut microbiota in children on Leyte island 査読

Jiro Nakayama, Azusa Yamamoto, Ladie A. Palermo-Conde, Kanako Higashi, Kenji Sonomoto, Julie Tan, Yuan Kun Lee

Frontiers in Microbiology   8 ( FEB )   2017年2月

Fermented papaya preparation restores age- related reductions in peripheral blood mononuclear cell cytolytic activity in tube- fed patients 査読

Yuhzo Fujita, Haruo Tsuno, Jiro Nakayama

PLoS One   12 ( 1 )   2017年1月

Microbial Community of Healthy Thai Vegetarians and Non-Vegetarians, Their Core Gut Microbiota, and Pathogen Risk. 査読 国際誌

Supatjaree Ruengsomwong, Orawan La-Ongkham, Jiahui Jiang, Bhusita Wannissorn, Jiro Nakayama, Sunee Nitisinprasert

Journal of microbiology and biotechnology   26 ( 10 )   1723 - 1735   2016年10月

Avellanin C, an inhibitor of quorum-sensing signaling in Staphylococcus aureus, from Hamigera ingelheimensis. 査読

Yasuhiro Igarashi, Fumiya Gohda, Taito Kadoshima, Takao Fukuda, Tomoaki Hanafusa, Akane Shojima, Jiro Nakayama, Gerald F Bills, Stephen Peterson

The Journal of antibiotics   68 ( 11 )   707 - 710   2015年11月

Diversity in gut bacterial community of school-age children in Asia. 査読 国際誌

Jiro Nakayama, Koichi Watanabe, Jiahui Jiang, Kazunori Matsuda, Shiou-Huei Chao, Pri Haryono, Orawan La-Ongkham, Martinus-Agus Sarwoko, I Nengah Sujaya, Liang Zhao, Kang-Ting Chen, Yen-Po Chen, Hsueh-Hui Chiu, Tomoko Hidaka, Ning-Xin Huang, Chikako Kiyohara, Takashi Kurakawa, Naoshige Sakamoto, Kenji Sonomoto, Kousuke Tashiro, Hirokazu Tsuji, Ming-Ju Chen, Vichai Leelavatcharamas, Chii-Cherng Liao, Sunee Nitisinprasert, Endang S Rahayu, Fa-Zheng Ren, Ying-Chieh Tsai, Yuan-Kun Lee

Scientific reports   5   8397 - 8397   2015年2月

Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria 査読

Said E. Desouky, Akane Shojima, Ravindra Pal Singh, Takahisa Matsufuji, Yasuhiro Igarashi, Takashi Suzuki, Tohru Yamagaki, Ken Ichi Okubo, Kaori Ohtani, Kenji Sonomoto, Jiro Nakayama

FEMS Microbiology Letters   362 ( 14 )   2015年1月

Rationale design of quorum-quenching peptides that target the VirSR system of Clostridium perfringens 査読

Ravindra Pal Singh, Ken Ichi Okubo, Kaori Ohtani, Keika Adachi, Kenji Sonomoto, Jiro Nakayama

FEMS Microbiology Letters   362 ( 22 )   2015年1月

Monitoring of the microbiota profile in nukadoko, a naturally fermented rice bran bed for pickling vegetables 査読

Hiroshi Ono, Shoko Nishio, Jun Tsurii, Tetsuhiro Kawamoto, Kenji Sonomoto, Jiro Nakayama

Journal of Bioscience and Bioengineering   118 ( 5 )   520 - 525   2014年1月

Quorum sensing in gram-positive bacteria Assay protocols for staphylococcal agr and enterococcal fsr systems 査読

Akane Shojima, Jiro Nakayama

Methods in Molecular Biology   1147   33 - 41   2014年1月

High-throughput screening of inhibitors targeting Agr/Fsr quorum sensing in staphylococcus aureus and enterococcus faecalis 査読

Said E. Desouky, Kenzo Nishiguchi, Takeshi Zendo, Yasuhiro Igarashi, Paul Williams, Kenji Sonomoto, Jiro Nakayama

Bioscience, Biotechnology and Biochemistry   77 ( 5 )   923 - 927   2013年6月

Development of a peptide antagonist against fsr quorum sensing of Enterococcus faecalis. 査読 国際誌

Jiro Nakayama, Ryoji Yokohata, Mami Sato, Takashi Suzuki, Takahisa Matsufuji, Kenzo Nishiguchi, Takeshi Kawai, Yosuke Yamanaka, Koji Nagata, Masaru Tanokura, Kenji Sonomoto

ACS chemical biology   8 ( 4 )   804 - 811   2013年4月

Aberrant structures of fecal bacterial community in allergic infants profiled by 16S rRNA gene pyrosequencing. 査読 国際誌

Jiro Nakayama, Takako Kobayashi, Shigemitsu Tanaka, Yuki Korenori, Atsushi Tateyama, Naoshige Sakamoto, Chikako Kiyohara, Taro Shirakawa, Kenji Sonomoto

FEMS immunology and medical microbiology   63 ( 3 )   397 - 406   2011年12月

16S rRNA pyrosequencing-based investigation of the bacterial community in nukadoko, a pickling bed of fermented rice bran. 査読 国際誌

Naoshige Sakamoto, Shigemitsu Tanaka, Kenji Sonomoto, Jiro Nakayama

International journal of food microbiology   144 ( 3 )   352 - 359   2011年1月

Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria. 査読 国際誌

Jiro Nakayama, Yumi Uemura, Kenzo Nishiguchi, Norito Yoshimura, Yasuhiro Igarashi, Kenji Sonomoto

Antimicrobial agents and chemotherapy   53 ( 2 )   580 - 586   2009年2月

Structure-activity relationship of gelatinase biosynthesis-activating pheromone of Enterococcus faecalis. 査読 国際誌

Kenzo Nishiguchi, Koji Nagata, Masaru Tanokura, Kenji Sonomoto, Jiro Nakayama

Journal of bacteriology   191 ( 2 )   641 - 650   2009年1月

Two homologous agr-like quorum-sensing systems cooperatively control adherence, cell morphology, and cell viability properties in Lactobacillus plantarum WCFS1 査読

Toshio Fujii, Colin Ingham, Jiro Nakayama, Marke Beerthuyzen, Ryoko Kunuki, Douwe Molenaar, Mark Sturme, Elaine Vaughan, Michiel Kleerebezem, Willem De Vos

Journal of Bacteriology   190 ( 23 )   7655 - 7665   2008年12月

Molecular monitoring of bacterial community structure in long-aged nukadoko: pickling bed of fermented rice bran dominated by slow-growing lactobacilli. 査読

Jiro Nakayama, Hiroyuki Hoshiko, Mizuki Fukuda, Hidetoshi Tanaka, Naoshige Sakamoto, Shigemitsu Tanaka, Kazutoshi Ohue, Kenji Sakai, Kenji Sonomoto

Journal of bioscience and bioengineering   104 ( 6 )   481 - 489   2007年12月

Differences in developing intestinal microbiota between allergic and non-allergic infants A pilot study in Japan 査読

Prapa Songjinda, Jiro Nakayama, Atsushi Tateyama, Shigemitsu Tanaka, Mina Tsubouchi, Chikako Kiyohara, Taro Shirakawa, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   71 ( 9 )   2338 - 2342   2007年11月

Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis. 査読 国際誌

Jiro Nakayama, Emi Tanaka, Reiko Kariyama, Koji Nagata, Kenzo Nishiguchi, Ritsuko Mitsuhata, Yumi Uemura, Masaru Tanokura, Hiromi Kumon, Kenji Sonomoto

Journal of bacteriology   189 ( 4 )   1358 - 1365   2007年2月

Revised model for Enterococcus faecalis fsr quorum-sensing system: the small open reading frame fsrD encodes the gelatinase biosynthesis-activating pheromone propeptide corresponding to staphylococcal agrd. 査読 国際誌

Jiro Nakayama, Shengmin Chen, Nozomi Oyama, Kenzo Nishiguchi, Essam A Azab, Emi Tanaka, Reiko Kariyama, Kenji Sonomoto

Journal of bacteriology   188 ( 23 )   8321 - 8326   2006年12月

An agr-like two-component regulatory system in Lactobacillus plantarum is involved in production of a novel cyclic peptide and regulation of adherence. 国際誌

Mark H J Sturme, Jiro Nakayama, Douwe Molenaar, Yoshiko Murakami, Ryoko Kunugi, Toshio Fujii, Elaine E Vaughan, Michiel Kleerebezem, Willem M de Vos

Journal of bacteriology   187 ( 15 )   5224 - 5235   2005年8月

Molecular monitoring of the developmental bacterial community in the gastrointestinal tract of Japanese infants 査読

Prapa Songjinda, Jiro Nakayama, Yumiko Kuroki, Shigemitsu Tanaka, Sanae Fukuda, Chikako Kiyohara, Tetsuro Yamamoto, Kunio Izuchi, Taro Shirakawa, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   69 ( 3 )   638 - 641   2005年3月

High-throughput PCR screening of genes for three-component regulatory system putatively involved in quorum sensing from low-G + C gram-positive bacteria. 国際誌

Jiro Nakayama, Antoon D L Akkermans, Willem M De Vos

Bioscience, biotechnology, and biochemistry   67 ( 3 )   480 - 489   2003年3月

Description of a 23.9-kilobase chromosomal deletion containing a region encoding fsr genes which mainly determines the gelatinase-negative phenotype of clinical isolates of Enterococcus faecalis in urine. 国際誌

Jiro Nakayama, Reiko Kariyama, Hiromi Kumon

Applied and environmental microbiology   68 ( 6 )   3152 - 3155   2002年6月

Functional analysis of TraA, the sex pheromone receptor encoded by pPD1, in a promoter region essential for the mating response in Enterococcus faecalis 査読

Takaaki Horii, Hiromichi Nagasawa, Jiro Nakayama

Journal of Bacteriology   184 ( 22 )   6343 - 6350   2002年1月

Chemical synthesis and biological activity of the gelatinase biosynthesis-activating pheromone of enterococcus faecalis and its analogs

Jiro Nakayama, Yong Cao, Takaaki Horii, Shohei Sakuda, Hiromichi Nagasawa

Bioscience, Biotechnology and Biochemistry   65 ( 10 )   2322 - 2325   2001年10月

Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis 査読

Jiro Nakayama, Yong Cao, Takaaki Horii, Shohei Sakuda, Antoon D L Akkermans, Willem M. De Vos, Hiromichi Nagasawa

Molecular Microbiology   41 ( 1 )   145 - 154   2001年1月

Analysis of pheromone binding and pheromone reception by Enterococcus faecalis 査読

Jiro Nakayama, Yuuichiro Takanami, Akinori Suzuki

Advances in Experimental Medicine and Biology   418   1033 - 1035   1997年10月

Targeted disruption of the PD78 gene (traF) reduces pheromone-inducible conjugal transfer of the bacteriocin plasmid pPD1 in Enterococcus faecalis 査読

Jiro Nakayama, Don B. Clewell, Akinori Suzuki

FEMS Microbiology Letters   128 ( 3 )   283 - 288   1995年5月

Cloning and characterization of a region of Enterococcus faecalis plasmid pPD1 encoding pheromone inhibitor (ipd), pheromone sensitivity (traC), and pheromone shutdown (traB) genes 査読

Jiro Nakayama, K. Yoshida, H. Kobayashi, A. Isogai, D. B. Clewell, A. Suzuki

Journal of Bacteriology   177 ( 19 )   5567 - 5573   1995年1月

Isolation and Structure of the Sex Pheromone Inhibitor, iAM373, of Enterococcus faecalis 査読

Jiro Nakayama, Yukitsugu Ono, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   59 ( 7 )   1358 - 1359   1995年1月

Isolation and Structure of the Enterococcus faecalis Sex Pheromone, cOB1, that Induces Conjugal Transfer of the Hemolysin/Bacteriocin Plasmids, pOB1 and pYI1 査読

Jiro Nakayama, Yuki Abe, Yukitsugu Ono, Akira Isogai, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   59 ( 4 )   703 - 705   1995年1月

The prgQ gene of the Enterococcus faecalis tetracycline resistance plasmid pCF10 encodes a peptide inhibitor, iCF10 査読

Jiro Nakayama, R. E. Ruhfel, G. M. Dunny, A. Isogai, A. Suzuki

Journal of Bacteriology   176 ( 23 )   7405 - 7408   1994年1月

C-Terminal Identification of AD74, a Proteolytic Product of Enterococcus faecalis Aggregation Substance Application of Liquid Chromatography/Mass Spectrometry 査読

Jiro Nakayama, Hiroshi Watarai, Akira Isogai, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   56 ( 1 )   127 - 131   1992年1月

Immunological Characterization of Pheromone-induced Proteins Associated with Sexual Aggregation in Enterococcus faecalis 査読

Jiro Nakayama, Hiroshi Watarai, Akira Isogai, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   56 ( 2 )   264 - 269   1992年1月

Nucleotide sequence of the sex pheromone inhibitor (iAD1) determinant ofEnterococcus faecalis conjugative plasmid pAD1 査読

Don B. Clewell, Linda T. Pontius, Florence Y. An, Yasuyoshi Ike, Akinori Suzuki, Jiro Nakayama

Plasmid   24 ( 2 )   156 - 161   1990年9月

Efficient extracellular expression of a foreign protein in smptomyos using secretory protease inhibitor (SSI) gene fusions 査読

Seiichi Taguchit, Izumi Kumagai, Jiro Nakayama, Akinori Suzuki, Kin Ichiro Miura

Nature Biotechnology   7 ( 10 )   1063 - 1066   1989年10月

Isolation and Structural Elucidation of a New Cyclitol Derivative, Streptol, as a Plant Growth Regulator 査読

Akira Isogai, Shouhei Sakuda, Jiro Nakayama, Satoshi Watanabe, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   51 ( 8 )   2277 - 2279   1987年1月

Probiotic Chocolate Containing <i>Lactobacillus plantarum</i> Dad-13 Alters the Gut Microbiota Composition of Undernourished Children in Lombok: A Randomized Double-Blind Trial

Rahayu, ES; Yoga, WK; Komalasari, H; Mariyatun, M; Yuda, WA; Manurung, NEP; Hasan, PN; Suharman, S; Pamungkaningtyas, FH; Nurfiana, DA; Pramesi, PC; Gatya, M; Therdtatha, P; Nakayama, J; Juffrie, M; Djaafar, TF; Marwati, T; Utami, T

INTERNATIONAL JOURNAL OF FOOD SCIENCE   2024   9493797   2024年8月   （ ISSN:2356-7015 eISSN:2314-5765 ）

Gut microbiome signatures associated with type 2 diabetes in obesity in Mongolia

Shinoda, A; Lkhagvajav, T; Mishima, R; Therdtatha, P; Jamiyan, D; Purevdorj, C; Sonomtseren, S; Chimeddorj, B; Namdag, B; Lee, YK; Demberel, S; Nakayama, J

FRONTIERS IN MICROBIOLOGY   15   1355396   2024年6月   （ ISSN:1664-302X eISSN:1664-302X ）

アカラシアにおけるTh17免疫反応と関連した食道細菌叢の変化とLC20不全リン酸化の相互作用(The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia)

Ikeda Hiroko, Ihara Eikichi, Takeya Kosuke, Mukai Koji, Onimaru Manabu, Ouchida Kenoki, Hata Yoshitaka, Bai Xiaopeng, Tanaka Yoshimasa, Sasaki Taisuke, Saito Fumiyo, Eto Masumi, Nakayama Jiro, Oda Yoshinao, Nakamura Masafumi, Inoue Haruhiro, Ogawa Yoshihiro

Journal of Gastroenterology   59 ( 5 )   361 - 375   2024年5月   （ ISSN:0944-1174 ）

The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia

Ikeda, H; Ihara, E; Takeya, K; Mukai, K; Onimaru, M; Ouchida, K; Hata, Y; Bai, XP; Tanaka, Y; Sasaki, T; Saito, F; Eto, M; Nakayama, J; Oda, Y; Nakamura, M; Inoue, H; Ogawa, Y

JOURNAL OF GASTROENTEROLOGY   59 ( 5 )   361 - 375   2024年3月   （ ISSN:0944-1174 eISSN:1435-5922 ）

Ziziphus spina-christi (L.) Willd. Leaves Extract Affecting agr Quorum Sensing System in Staphylococcus aureus

Refai, MY; Elazzazy, AM; Abu-Elghait, M; Desouky, S; Albureikan, MOI; Nakayama, J

ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING   49 ( 1 )   97 - 105   2024年1月   （ ISSN:2193-567X eISSN:2191-4281 ）

Impact of vegetables on the microbiota of the rice bran pickling bed Nukadoko

SUGIURA Shunsaku, IKEDA Mika, NAKAMURA Yuichi, MISHIMA Riko, MORISHITA Mika, NAKAYAMA Jiro

Bioscience of Microbiota, Food and Health   advpub ( 0 )   2024年   （ eISSN:21863342 ）

Effect of lactic acid bacterial starter KUB-G2 on grass silage quality and its microbial community performed using 140-ton plastic bag silos: a large-scale study

Therdtatha, P; La-Ongkham, O; Nakphaichit, M; Mapato, C; Rungruang, S; Nakayama, J; Nitisinprasert, S

QUALITY ASSURANCE AND SAFETY OF CROPS & FOODS   15   1 - 13   2024年   （ ISSN:1757-8361 eISSN:1757-837X ）

Cyclic pairwise interaction representing a rock-paper-scissors game maintains the population of the vulnerable yeast <i>Saccharomyces cerevisiae</i> within a multispecies sourdough microbiome 国際誌

Oshiro, M; Zendo, T; Tashiro, Y; Nakayama, J

MICROBIOLOGY SPECTRUM   11 ( 6 )   e0137023   2023年12月   （ ISSN:2165-0497 ）

Interception of Epoxide ring to quorum sensing system in Enterococcus faecalis and Staphylococcus aureus 国際誌

Refai, MY; Elazzazy, AM; Desouky, SE; Abu-Elghait, M; Fayed, EA; Alajel, SM; Alajlan, AA; Albureikan, MO; Nakayama, J

AMB EXPRESS   13 ( 1 )   126 - 126   2023年11月   （ ISSN:2191-0855 ）

Interaction of diet and gut microbiome in Asians and its effect on their health

Nakayama, J; Mishima, R; Shinoda, A; Rahayu, ES; Nakphaichit, M; Demberel, S; Dalmacio, LM; Lee, YK

ANNALS OF NUTRITION AND METABOLISM   79   135 - 135   2023年8月   （ ISSN:0250-6807 eISSN:1421-9697 ）

Longitudinal gut mycobiota changes in Japanese infants during first three years of life

Mishima, R; Tanaka, M; Momoda, R; Sanefuji, M; Morokuma, S; Ogawa, M; Kato, K; Nakayama, J

JOURNAL OF BIOSCIENCE AND BIOENGINEERING   135 ( 4 )   266 - 273   2023年4月   （ ISSN:1389-1723 eISSN:1347-4421 ）

生後3年間の日本人乳児における長期的腸内真菌叢の変化(Longitudinal gut mycobiota changes in Japanese infants during first three years of life)

Mishima Riko, Tanaka Masaru, Momoda Rie, Sanefuji Masafumi, Morokuma Seiichi, Ogawa Masanobu, Kato Kiyoko, Nakayama Jiro

Journal of Bioscience and Bioengineering   135 ( 4 )   266 - 273   2023年4月   （ ISSN:1389-1723 ）

修士学生に就活フリーの時間を

中山 二郎

化学と生物   61 ( 3 )   103 - 103   2023年3月   （ ISSN:0453073X eISSN:18836852 ）

変わりゆくアジア食とアジア人の腸内細菌叢

中山 二郎

Microbiome Science   2   6 - 12   2023年

各種胆汁酸分子の発芽誘導能を用いた難培養性腸内細菌の分離と日本人腸内細菌叢カクテルの創製

中山 二郎

発酵研究所助成研究報告集   37 ( 0 )   128   2023年   （ ISSN:00738751 eISSN:27592553 ）

DYSBIOSIS IN CHRONIC HEPATITIS C WORSENS WITH AGING

Inoue, T; Nakayama, J; Moriya, K; Kawaratani, H; Iio, E; Matsuura, K; Watanabe, T; Nagaoka, K; Tateyama, M; Setoyama, H; Yoshimaru, Y; Yoshiji, H; Tanaka, Y

HEPATOLOGY   76   S1293 - S1294   2022年10月   （ ISSN:0270-9139 eISSN:1527-3350 ）

Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome 国際誌

Nagao, JI; Kishikawa, S; Tanaka, H; Toyonaga, K; Narita, Y; Negoro-Yasumatsu, K; Tasaki, S; Arita-Morioka, KI; Nakayama, J; Tanaka, Y

CELL REPORTS   40 ( 10 )   111314 - 111314   2022年9月   （ ISSN:2211-1247 ）

The association between early formula and reduced risk of cow's milk allergy during the first three year of life: a Japanese cohort study 国際誌

Ikari, K; Tezuka, J; Sanefuji, M; Nakayama, J; Nishima, D; Sonoda, Y; Ogawa, M; Shimono, M; Suga, R; Honjo, S; Kusuhara, K; Ohga, S

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY   18 ( 1 )   71 - 71   2022年8月   （ ISSN:1710-1492 ）

Glucosylceramide Changes Bacterial Metabolism and Increases Gram-Positive Bacteria through Tolerance to Secondary Bile Acids In Vitro 査読 国際誌

Dai, HH; Otsuka, A; Tanabe, K; Yanagita, T; Nakayama, J; Kitagaki, H

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   23 ( 10 )   2022年5月   （ ISSN:16616596 eISSN:1422-0067 ）

Characterization and Demonstration of Mock Communities as Control Reagents for Accurate Human Microbiome Community Measurements 査読 国際誌

Tourlousse D.M., Narita K., Miura T., Ohashi A., Matsuda M., Ohyama Y., Shimamura M., Furukawa M., Kasahara K., Kameyama K., Saito S., Goto M., Shimizu R., Mishima R., Nakayama J., Hosomi K., Kunisawa J., Terauchi J., Sekiguchi Y., Kawasaki H.

Microbiology Spectrum   10 ( 2 )   e0191521   2022年4月

Characterization and Demonstration of Mock Communities as Control Reagents for Accurate Human Microbiome Community Measurements

Tourlousse, DM; Narita, K; Miura, T; Ohashi, A; Matsuda, M; Ohyama, Y; Shimamura, M; Furukawa, M; Kasahara, K; Kameyama, K; Saito, S; Goto, M; Shimizu, R; Mishima, R; Nakayama, J; Hosomi, K; Kunisawa, J; Terauchi, J; Sekiguchi, Y; Kawasaki, H

MICROBIOLOGY SPECTRUM   10 ( 2 )   2022年4月   （ ISSN:2165-0497 ）

Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study 査読 国際誌

Desouky, SE; Abu-Elghait, M; Fayed, EA; Selim, S; Yousuf, B; Igarashi, Y; Abdel-Wahab, BA; Alsuhaibani, AM; Sonomoto, K; Nakayama, J

METABOLITES   12 ( 3 )   2022年3月   （ ISSN:2218-1989 eISSN:2218-1989 ）

“胆汁酸”を介した腸内細菌と宿主のクロストーク

田中 優, 中山 二郎

化学と生物   60 ( 2 )   79 - 88   2022年2月   （ ISSN:0453073X eISSN:18836852 ）

Gut microbiome profiles in Thai healthy pregnant women and its association with types of foods

Phoonlapdacha, P; Tangshewinsirikul, C; Phosuwattanakul, J; Kittisakmontri, K; Nitisinprasert, S; Nakayama, J; Prombutara, P; Suthutvoravut, U; Chongviriyaphan, N

BMC PREGNANCY AND CHILDBIRTH   22 ( 1 )   79   2022年1月   （ eISSN:1471-2393 ）

Bile acid dysmetabolism in the gut-microbiota-liver axis under hepatitis C virus infection 査読 国際誌

Inoue, T; Funatsu, Y; Ohnishi, M; Isogawa, M; Kawashima, K; Tanaka, M; Moriya, K; Kawaratani, H; Momoda, R; Iio, E; Nakagawa, H; Suzuki, Y; Matsuura, K; Fujiwara, K; Nakajima, A; Yoshiji, H; Nakayama, J; Tanaka, Y

LIVER INTERNATIONAL   42 ( 1 )   124 - 134   2022年1月   （ ISSN:1478-3223 eISSN:1478-3231 ）

Crisis of the Asian gut: associations among diet, microbiota, and metabolic diseases

Therdtatha, P; Shinoda, A; Nakayama, J

BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH   41 ( 3 )   83 - 93   2022年   （ ISSN:2186-6953 eISSN:21863342 ）

Characterization of the Biosynthetic Gene Cluster of Enterocin F4-9, a Glycosylated Bacteriocin. 査読 国際誌

Mohamed Abdelfattah Maky, Naoki Ishibashi, Jiro Nakayama, Takeshi Zendo

Microorganisms   9 ( 11 )   2021年11月

Mechanistic Insight into Yeast Bloom in a Lactic Acid Bacteria Relaying-Community in the Start of Sourdough Microbiota Evolution. 査読 国際誌

Mugihito Oshiro, Masaru Tanaka, Rie Momoda, Takeshi Zendo, Jiro Nakayama

Microbiology spectrum   9 ( 2 )   e0066221   2021年10月

Cultivation of Spore-Forming Gut Microbes Using a Combination of Bile Acids and Amino Acids. 査読 国際誌

Sakura Onizuka, Masaru Tanaka, Riko Mishima, Jiro Nakayama

Microorganisms   9 ( 8 )   2021年8月

Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis. 査読 国際誌

Yuichiro Nishihara, Haruei Ogino, Masaru Tanaka, Eikichi Ihara, Keita Fukaura, Kei Nishioka, Takatoshi Chinen, Yoshimasa Tanaka, Jiro Nakayama, Dongchon Kang, Yoshihiro Ogawa

Scientific reports   11 ( 1 )   13743 - 13743   2021年7月

Diversity and dynamics of sourdough lactic acid bacteriota created by a slow food fermentation system. 査読

Mugihito Oshiro, Takeshi Zendo, Jiro Nakayama

Journal of bioscience and bioengineering   131 ( 4 )   333 - 340   2021年4月

Molecular characterization of the possible regulation of multiple bacteriocin production through a three-component regulatory system in Enterococcus faecium NKR-5-3 査読 国際誌

Naoki Ishibashi, Naho Matsumoto, Rodney Honrada Perez, Shun Iwatani, Haruki Sugino, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of Bioscience and Bioengineering   131 ( 2 )   131 - 138   2021年2月

The salivary microbiota of Thai adults with metabolic disorders and association with diet. 査読 国際誌

Tawatchai Chumponsuk, Lucsame Gruneck, Eleni Gentekaki, Paiboon Jitprasertwong, Niwed Kullawong, Jiro Nakayama, Siam Popluechai

Archives of oral biology   122   105036 - 105036   2021年2月

Gut Microbiota and Short-Chain Fatty Acid Profile between Normal and Moderate Malnutrition Children in Yogyakarta, Indonesia. 査読 国際誌

Rafli Zulfa Kamil, Agnes Murdiati, Mohammad Juffrie, Jiro Nakayama, Endang Sutriswati Rahayu

Microorganisms   9 ( 1 )   1 - 15   2021年1月

Processing and secretion of non-cognate bacteriocins by EnkT, an ABC transporter from a multiple-bacteriocin producer, Enterococcus faecium NKR-5-3. 査読

Hirotoshi Sushida, Miyuki Sakei, Rodney H Perez, Naoki Ishibashi, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   130 ( 6 )   596 - 603   2020年12月

Alteration in faecal bile acids, gut microbial composition and diversity after laparoscopic sleeve gastrectomy 査読 国際誌

T. Ikeda, M. Aida, Y. Yoshida, S. Matsumoto, M. Tanaka, J. Nakayama, Y. Nagao, R. Nakata, E. Oki, T. Akahoshi, S. Okano, M. Nomura, M. Hashizume, Y. Maehara

British Journal of Surgery   107 ( 12 )   1673 - 1685   2020年11月

Indonesian children fecal microbiome from birth until weaning was different from microbiomes of their mothers. 査読 国際誌

Wei Wei Thwe Khine, Endang Sutriswati Rahayu, Ting Yi See, Sherwin Kuah, Seppo Salminen, Jiro Nakayama, Yuan-Kun Lee

Gut microbes   12 ( 1 )   1761240 - 1761240   2020年11月

Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis. 査読 国際誌

Masanori Furukawa, Kei Moriya, Jiro Nakayama, Takako Inoue, Rie Momoda, Hideto Kawaratani, Tadashi Namisaki, Shinya Sato, Akitoshi Douhara, Kosuke Kaji, Mitsuteru Kitade, Naotaka Shimozato, Yasuhiko Sawada, Soichiro Saikawa, Hiroaki Takaya, Koh Kitagawa, Takemi Akahane, Akira Mitoro, Junichi Yamao, Yasuhito Tanaka, Hitoshi Yoshiji

Hepatology research : the official journal of the Japan Society of Hepatology   50 ( 7 )   840 - 852   2020年7月

Impact of pH on succession of sourdough lactic acid bacteria communities and their fermentation properties 査読 国際誌

Mugihito OSHIRO, Masaru TANAKA, Takeshi ZENDO, Jiro NAKAYAMA

Bioscience of Microbiota, Food and Health   39 ( 3 )   152 - 159   2020年7月

Age-related changes in the gut microbiota and the core gut microbiome of healthy Thai humans. 査読 国際誌

Orawan La-Ongkham, Massalin Nakphaichit, Jiro Nakayama, Suttipun Keawsompong, Sunee Nitisinprasert

3 Biotech   10 ( 6 )   276 - 276   2020年6月

Age-related changes in the gut microbiota and the core gut microbiome of healthy Thai humans. 査読 国際誌

Orawan La-Ongkham, Massalin Nakphaichit, Jiro Nakayama, Suttipun Keawsompong, Sunee Nitisinprasert

3 Biotech   10 ( 6 )   276 - 276   2020年6月

Relation between cell-bound exopolysaccharide production via plasmid-encoded genes and rugose colony morphology in the probiotic Lactobacillus brevis KB290. 査読 国際誌

Masanori Fukao, Takeshi Zendo, Takuro Inoue, Nobuo Fuke, Tomoo Moriuchi, Yasuhiro Yamane, Jiro Nakayama, Kenji Sonomoto, Tetsuya Fukaya

Animal science journal = Nihon chikusan Gakkaiho   90 ( 12 )   1575 - 1580   2019年12月

The gelatinase biosynthesis-activating pheromone binds and stabilises the FsrB membrane protein in Enterococcus faecalis quorum sensing 査読 国際誌

594 ( 3 )   553 - 563   2019年10月

Plasmid-encoded glycosyltransferase operon is responsible for exopolysaccharide production, cell aggregation, and bile resistance in a probiotic strain, Lactobacillus brevis KB290. 査読

128 ( 4 )   391 - 397   2019年10月

Koji glycosylceramide commonly contained in Japanese traditional fermented foods alters cholesterol metabolism in obese mice. 査読 国際誌

Hiroshi Hamajima, Masaru Tanaka, Miyuki Miyagawa, Mayuko Sakamoto, Tsuyoshi Nakamura, Teruyoshi Yanagita, Megumi Nishimukai, Susumu Mitsutake, Jiro Nakayama, Koji Nagao, Hiroshi Kitagaki

Bioscience, biotechnology, and biochemistry   83 ( 8 )   1514 - 1522   2019年8月

Protective effect of lactobacillus reuteri KUB-AC5 against salmonella enteritidis challenge in chickens 査読 国際誌

M. Nakphaichit, S. Sobanbua, S. Siemuang, W. Vongsangnak, Jiro Nakayama, S. Nitisinprasert

Beneficial Microbes   10 ( 1 )   43 - 54   2019年1月

Evaluation of leader peptides that affect the secretory ability of a multiple bacteriocin transporter, EnkT. 査読

Hirotoshi Sushida, Naoki Ishibashi, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   126 ( 1 )   23 - 29   2018年7月

Developing anti-virulence chemotherapies by exploiting the diversity of microbial quorum sensing systems

Basit Yousuf, Keika Adachi, Jiro Nakayama

Biotechnological Applications of Quorum Sensing Inhibitors   151 - 208   2018年5月

Developing anti-virulence chemotherapies by exploiting the diversity of microbial quorum sensing systems

Basit Yousuf, Keika Adachi, Jiro Nakayama

Biotechnological Applications of Quorum Sensing Inhibitors   151 - 208   2018年5月

Evaluation of leader peptides that affect the secretory ability of a multiple bacteriocin transporter, EnkT 査読 国際誌

Hirotoshi Sushida, Naoki Ishibashi, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of Bioscience and Bioengineering   2018年1月

16S rRNA Metagenomics of Asian Gut Microbiota 招待 査読 国際誌

Juma Kisuse, Jiro Nakayama

Understanding Host-Microbiome Interactions - An Omics Approach Omics of Host-Microbiome Association   71 - 81   2017年9月

In vitro synergistic activities of cefazolin and nisin A against mastitis pathogens. 査読

Kohei Kitazaki, Shoko Koga, Kohei Nagatoshi, Koichi Kuwano, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto, Hitoshi Ano, Hiromu Katamoto

The Journal of veterinary medical science   79 ( 9 )   1472 - 1479   2017年9月

Asian gut microbiome 査読

Jiro Nakayama, Heping Zhang, Yuan Kun Lee

Science Bulletin   62 ( 12 )   816 - 817   2017年6月

Mutations near the cleavage site of enterocin NKR-5-3B prepeptide reveal new insights into its biosynthesis. 査読 国際誌

Rodney H Perez, Haruki Sugino, Naoki Ishibashi, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Microbiology (Reading, England)   163 ( 4 )   431 - 441   2017年4月

In vitro synergistic activities of cefazolin and nisin a against mastitis pathogens 査読

Kohei Kitazaki, Shoko Koga, Kohei Nagatoshi, Koichi Kuwano, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto, Hitoshi Ano, Hiromu Katamoto

Journal of Veterinary Medical Science   79 ( 9 )   1472 - 1479   2017年1月

The effects of administration of the Lactobacillus gasseri strain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome 査読

K. Nobutani, D. Sawada, S. Fujiwara, Y. Kuwano, K. Nishida, J. Nakayama, H. Kutsumi, T. Azuma, K. Rokutan

Journal of Applied Microbiology   122 ( 1 )   212 - 224   2017年1月

Japanese traditional dietary fungus koji Aspergillus oryzae functions as a prebiotic for Blautia coccoides through glycosylceramide Japanese dietary fungus koji is a new prebiotic 査読

Hiroshi Hamajima, Haruka Matsunaga, Ayami Fujikawa, Tomoya Sato, Susumu Mitsutake, Teruyoshi Yanagita, Koji Nagao, Jiro Nakayama, Hiroshi Kitagaki

SpringerPlus   5 ( 1 )   2016年12月

LnqR, a TetR-family transcriptional regulator, positively regulates lacticin Q production in Lactococcus lactis QU 5. 査読 国際誌

Shun Iwatani, Naoki Ishibashi, Floirendo P Flores, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

FEMS microbiology letters   363 ( 18 )   2016年9月

Bacterial community structures of deep-sea water investigated by molecular biological techniques. 査読 国際誌

Takeshi Terahara, Katsuhisa Yamada, Jiro Nakayama, Yasuhiro Igarashi, Takeshi Kobayashi, Chiaki Imada

Gene   576 ( 2 Pt 1 )   696 - 700   2016年2月

Functional Analysis of Genes Involved in the Biosynthesis of Enterocin NKR-5-3B, a Novel Circular Bacteriocin. 査読 国際誌

Rodney H Perez, Naoki Ishibashi, Tomoko Inoue, Kohei Himeno, Yoshimitsu Masuda, Narukiko Sawa, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of bacteriology   198 ( 2 )   291 - 300   2016年1月

In vitro catalytic activity of N-terminal and C-terminal domains in NukM, the post-translational modification enzyme of nukacin ISK-1. 査読

Chinatsu Shimafuji, Megumi Noguchi, Mami Nishie, Jun-Ichi Nagao, Kouki Shioya, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   120 ( 6 )   624 - 629   2015年12月

Complete genome sequence of Lactobacillus acetotolerans RIB 9124 (NBRC 13120) isolated from putrefied (hiochi) Japanese sake 査読

Hidehiro Toh, Hidetoshi Morita, Hiroyuki Tsuji, Kazuhiro Iwashita, Nami Goto, Jiro Nakayama, Mitsuo Sekine, Yumiko Kato, Ken Ichiro Suzuki, Nobuyuki Fujita

Journal of Biotechnology   214   214 - 215   2015年11月

Rationale design of quorum-quenching peptides that target the VirSR system of Clostridium perfringens. 査読 国際誌

Ravindra Pal Singh, Ken-Ichi Okubo, Kaori Ohtani, Keika Adachi, Kenji Sonomoto, Jiro Nakayama

FEMS microbiology letters   362 ( 22 )   2015年11月

Complete genome sequence of Lactobacillus acetotolerans RIB 9124 (NBRC 13120) isolated from putrefied (hiochi) Japanese sake. 査読 国際誌

Hidehiro Toh, Hidetoshi Morita, Hiroyuki Tsuji, Kazuhiro Iwashita, Nami Goto, Jiro Nakayama, Mitsuo Sekine, Yumiko Kato, Ken-ichiro Suzuki, Nobuyuki Fujita

Journal of biotechnology   214   214 - 5   2015年11月

Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp. 査読 国際誌

Yasuhiro Igarashi, Kazuki Yamamoto, Takao Fukuda, Akane Shojima, Jiro Nakayama, Lorena Carro, Martha E Trujillo

Journal of natural products   78 ( 11 )   2827 - 2831   2015年11月

Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. 査読 国際誌

Biochemistry   54 ( 31 )   4863 - 4876   2015年8月

Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria. 査読 国際誌

Said E Desouky, Akane Shojima, Ravindra Pal Singh, Takahisa Matsufuji, Yasuhiro Igarashi, Takashi Suzuki, Tohru Yamagaki, Ken-Ichi Okubo, Kaori Ohtani, Kenji Sonomoto, Jiro Nakayama

FEMS microbiology letters   362 ( 14 )   2015年7月

Development of quorum-sensing inhibitors targeting the fsr system of enterococcus faecalis 査読

Ravindra Pal Singh, Jiro Nakayama

Quorum Sensing vs Quorum Quenching: A Battle with no end in Sight   319 - 326   2015年1月

Development of quorum-sensing inhibitors targeting the fsr system of enterococcus faecalis 査読

Ravindra Pal Singh, Jiro Nakayama

Quorum Sensing vs Quorum Quenching: A Battle with no end in Sight   319 - 326   2015年1月

Quorum-sensing systems in enterococci 査読

Ravindra Pal Singh, Jiro Nakayama

Quorum Sensing vs Quorum Quenching: A Battle with no end in Sight   155 - 163   2015年1月

Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. 査読 国際誌

Tadao Enomoto, Masanori Sowa, Keiji Nishimori, Shinichiro Shimazu, Akira Yoshida, Kazuko Yamada, Fukumi Furukawa, Takemasa Nakagawa, Naotake Yanagisawa, Noriyuki Iwabuchi, Toshitaka Odamaki, Fumiaki Abe, Jiro Nakayama, Jin-Zhong Xiao

Allergology international : official journal of the Japanese Society of Allergology   63 ( 4 )   575 - 85   2014年12月

Gene cluster responsible for secretion of and immunity to multiple bacteriocins, the NKR-5-3 enterocins. 査読 国際誌

Naoki Ishibashi, Kohei Himeno, Yoshimitsu Masuda, Rodney Honrada Perez, Shun Iwatani, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   80 ( 21 )   6647 - 55   2014年11月

Monitoring of the microbiota profile in nukadoko, a naturally fermented rice bran bed for pickling vegetables. 査読

Hiroshi Ono, Shoko Nishio, Jun Tsurii, Tetsuhiro Kawamoto, Kenji Sonomoto, Jiro Nakayama

Journal of bioscience and bioengineering   118 ( 5 )   520 - 5   2014年11月

Effects of Japanese pepper and red pepper on the microbial community during nukadoko fermentation 査読 国際誌

H. Ono, S. Nishio, J. Tsurii, T. Kawamoto, K. Sonomoto and J. Nakayama

Biosci Microbiota Food Health   34 ( 1 )   2014年9月

Senior Thai fecal microbiota comparison between vegetarians and non-vegetarians using PCR-DGGE and real-time PCR. 査読 国際誌

Supatjaree Ruengsomwong, Yuki Korenori, Naoshige Sakamoto, Bhusita Wannissorn, Jiro Nakayama, Sunee Nitisinprasert

Journal of microbiology and biotechnology   24 ( 8 )   1026 - 33   2014年8月

Biological function of a DUF95 superfamily protein involved in the biosynthesis of a circular bacteriocin, leucocyclicin Q. 査読

Fuqin Mu, Yoshimitsu Masuda, Takeshi Zendo, Hiroshi Ono, Hiroshi Kitagawa, Haruo Ito, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   117 ( 2 )   158 - 164   2014年2月

Draft Genome Sequence of Lactobacillus namurensis Chizuka 01, Isolated from Nukadoko, a Pickling Bed of Fermented Rice Bran. 査読 国際誌

Keita Kato, Hidehiro Toh, Naoshige Sakamoto, Kazuki Mori, Kosuke Tashiro, Naruhiro Hibi, Kenji Sonomoto, Jiro Nakayama

Genome announcements   2 ( 1 )   2014年2月

Bactericidal activity of nukacin ISK-1 An alternative mode of action 査読

Urmi Roy, Mohammad Riazul Islam, Jun Ichi Nagao, Hiroshi Iida, Abdullah Al Mahin, Mengqi Li, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   78 ( 7 )   1270 - 1273   2014年1月

Transcriptomic study reveals new pathways and genes involved in Enterococcus faecalis V583 response to a therapeutic dose of vancomycin 査読

Archives of Clinical Microbiology   5 ( 1 )   2014年1月

Gene cluster responsible for secretion of and immunity to multiple bacteriocins, the NKR-5-3 enterocins 査読

Naoki Ishibashi, Kohei Himeno, Yoshimitsu Masuda, Rodney Honrada Perez, Shun Iwatani, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Applied and Environmental Microbiology   80 ( 21 )   6647 - 6655   2014年1月

Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota 査読

Tadao Enomoto, Masanori Sowa, Keiji Nishimori, Shinichiro Shimazu, Akira Yoshida, Kazuko Yamada, Fukumi Furukawa, Takemasa Nakagawa, Naotake Yanagisawa, Noriyuki Iwabuchi, Toshitaka Odamaki, Fumiaki Abe, Jiro Nakayama, Jin Zhong Xiao

Allergology International   63 ( 4 )   575 - 585   2014年1月

Lethal hydroxyl radical accumulation by a lactococcal bacteriocin, lacticin Q. 査読 国際誌

Mengqi Li, Fuminori Yoneyama, Nayu Toshimitsu, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Antimicrobial agents and chemotherapy   57 ( 8 )   3897 - 3902   2013年8月

Drosophila Host Model Reveals New Enterococcus faecalis Quorum-Sensing Associated Virulence Factors 査読

PLoS One   8 ( 5 )   2013年5月

Up to species-level community analysis of human gut microbiota by 16S rRNA amplicon pyrosequencing 査読 国際誌

Nakayama, J., Jiang, J., Watanabe, K., Chen, K., Ninxin, H., Matsuda, K., Kurakawa, T., Tsuji, H., Sonomoto, K., and Lee, Y.-K.

Bioscience, Microflora, Food, Health   32   2013年5月

Bifunctional gene cluster lnqBCDEF mediates bacteriocin production and immunity with differential genetic requirements. 査読 国際誌

Shun Iwatani, Yuko Horikiri, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   79 ( 7 )   2446 - 2449   2013年4月

Interactions of the intact FsrC membrane histidine kinase with the tricyclic peptide inhibitor siamycin I revealed through synchrotron radiation circular dichroism. 査読 国際誌

Mary K Phillips-Jones, Simon G Patching, Shalini Edara, Jiro Nakayama, Rohanah Hussain, Giuliano Siligardi

Physical chemistry chemical physics : PCCP   15 ( 2 )   444 - 447   2013年1月

Identification of the genes involved in the secretion and self-immunity of lacticin Q, an unmodified leaderless bacteriocin from Lactococcus lactis QU 5. 査読 国際誌

Shun Iwatani, Fuminori Yoneyama, Shiho Miyashita, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Microbiology (Reading, England)   158 ( 12 )   2927 - 2935   2012年12月

Monitoring of the multiple bacteriocin production by Enterococcus faecium NKR-5-3 through a developed liquid chromatography and mass spectrometry-based quantification system. 査読

Rodney H Perez, Kohei Himeno, Naoki Ishibashi, Yoshimitsu Masuda, Takeshi Zendo, Koji Fujita, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   114 ( 5 )   490 - 496   2012年11月

Interactions of the intact FsrC membrane histidine kinase with its pheromone ligand GBAP revealed through synchrotron radiation circular dichroism 査読

Simon G. Patching, Shalini Edara, Pikyee Ma, Jiro Nakayama, Rohanah Hussain, Giuliano Siligardi, Mary K. Phillips-Jones

Biochimica et Biophysica Acta - Biomembranes   1818 ( 7 )   1595 - 1602   2012年7月

Identification of enterocin NKR-5-3C, a novel class IIa bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3 査読

Kohei Himeno, Koji Fujita, Takeshi Zendo, Pongtep Wilaipun, Naoki Ishibashi, Yoshimitsu Masuda, Fuminori Yoneyama, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   76 ( 6 )   1245 - 1247   2012年6月

Purification and characterization of multiple bacteriocins and an inducing peptide produced by Enterococcus faecium NKR-5-3 from Thai fermented fish 査読

Naoki Ishibashi, Kohei Himeno, Koji Fujita, Yoshimitsu Masuda, Rodney Honrada Perez, Takeshi Zendo, Pongtep Wilaipun, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   76 ( 5 )   947 - 953   2012年5月

The incongruent gelatinase genotype and phenotype in Enterococcus faecalis are due to shutting off the ability to respond to the gelatinase biosynthesis-activating pheromone (GBAP) quorum-sensing signal 査読

Microbiology   158 ( 2 )   519 - 528   2012年2月

The incongruent gelatinase genotype and phenotype in Enterococcus faecalis are due to shutting off the ability to respond to the gelatinase biosynthesis-activating pheromone (GBAP) quorum-sensing signal. 査読 国際誌

Microbiology (Reading, England)   158 ( 2 )   519 - 528   2012年2月

Ring A of nukacin ISK-1: a lipid II-binding motif for type-A(II) lantibiotic. 査読 国際誌

Mohammad R Islam, Mami Nishie, Jun-ichi Nagao, Takeshi Zendo, Sandro Keller, Jiro Nakayama, Daisuke Kohda, Hans-Georg Sahl, Kenji Sonomoto

Journal of the American Chemical Society   134 ( 8 )   3687 - 3690   2012年2月

Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1. 査読 国際誌

Naruhiko Sawa, Pongtep Wilaipun, Seisuke Kinoshita, Takeshi Zendo, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   78 ( 3 )   900 - 903   2012年2月

Characterization and identification of weissellicin Y and weissellicin M, novel bacteriocins produced by Weissella hellenica QU 13 査読

Y. Masuda, T. Zendo, N. Sawa, R. H. Perez, J. Nakayama, K. Sonomoto

Journal of Applied Microbiology   112 ( 1 )   99 - 108   2012年1月

Enhanced production of nukacin D13E in Lactococcus lactis NZ9000 by the additional expression of immunity genes. 査読 国際誌

Tijo Varghese Puramattathu, Mohammad R Islam, Mami Nishie, Sae Yanagihara, Jun-ichi Nagao, Ken-ichi Okuda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Applied microbiology and biotechnology   93 ( 2 )   671 - 678   2012年1月

Engineering unusual amino acids into peptides using lantibiotic synthetase

Jun Ichi Nagao, Kouki Shioya, Yoshitaka Harada, Ken Ichi Okuda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Heterologous Gene Expression in E.coli Methods and Protocols   705   225 - 236   2011年12月

The effect of including Lactobacillus reuteri KUB-AC5 during post-hatch feeding on the growth and ileum microbiota of broiler chickens 査読

M. Nakphaichit, S. Thanomwongwattana, C. Phraephaisarn, N. Sakamoto, S. Keawsompong, J. Nakayama, S. Nitisinprasert

Poultry Science   90 ( 12 )   2753 - 2765   2011年12月

Survey of Overactive Bladder Symptoms Influencing Bother Before and After Treatment With Tamsulosin Hydrochloride in Japanese Patients With Benign Prostatic Hyperplasia 査読

Akira Tsujimura, Tetsuya Takao, Yasushi Miyagawa, Hidenobu Okuda, Keisuke Yamamoto, Shinichiro Fukuhara, Jiro Nakayama, Tomohiro Ueda, Hiroshi Kiuchi, Toshiaki Hirai, Yuichi Tsujimoto, Hidenobu Miura, Nobuteru Kanno, Makoto Higashino, Yoshihiro Nakamura, Kenji Nishimura, Norio Nonomura

UROLOGY   78 ( 5 )   1058 - 1062   2011年11月

Anti-HIV siamycin I directly inhibits autophosphorylation activity of the bacterial FsrC quorum sensor and other ATP-dependent enzyme activities. 査読 国際誌

Pikyee Ma, Kenzo Nishiguchi, Hayley M Yuille, Lianne M Davis, Jiro Nakayama, Mary K Phillips-Jones

FEBS letters   585 ( 17 )   2660 - 2664   2011年9月

Crystallization and preliminary X-ray analysis of a putative sensor histidine kinase domain: the C-terminal domain of HksP4 from Aquifex aeolicus VF5. 査読 国際誌

Shoichiro Horita, Yosuke Yamanaka, Akihiro Yamamura, Akitoshi Okada, Jiro Nakayama, Koji Nagata, Masaru Tanokura

Acta crystallographica. Section F, Structural biology and crystallization communications   67 ( 7 )   803 - 807   2011年7月

Lacticin Q-mediated selective toxicity depending on physicochemical features of membrane components 査読

Fuminori Yoneyama, Kanako Ohno, Yuichi Imura, Mengqi Li, Takeshi Zendo, Jiro Nakayama, Katsumi Matsuzaki, Kenji Sonomoto

Antimicrobial Agents and Chemotherapy   55 ( 5 )   2446 - 2450   2011年5月

Lantibiotic transporter requires cooperative functioning of the peptidase domain and the ATP binding domain 査読

Mami Nishie, Makoto Sasaki, Jun Ichi Nagao, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Journal of Biological Chemistry   286 ( 13 )   11163 - 11169   2011年4月

Urgency Is an Independent Factor for Sleep Disturbance in Men with Obstructive Sleep Apnea 査読

Akira Tsujimura, Tetsuya Takao, Yasushi Miyagawa, Keisuke Yamamoto, Shinichiro Fukuhara, Jiro Nakayama, Hiroshi Kiuchi, Nakamori Suganuma, Tadashi Nakamura, Takayuki Kumano-go, Yoshiro Sugita, Norio Nonomura, Akihiko Okuyama

UROLOGY   76 ( 4 )   967 - 970   2010年10月

Enterocin X, a novel two-peptide bacteriocin from Enterococcus faecium KU-B5, has an antibacterial spectrum entirely different from those of its component peptides. 査読 国際誌

Chih-Bo Hu, Wanna Malaphan, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   76 ( 13 )   4542 - 4545   2010年7月

Identification and characterization of novel multiple bacteriocins produced by Leuconostoc pseudomesenteroides QU 15 査読

N. Sawa, K. Okamura, T. Zendo, K. Himeno, J. Nakayama, K. Sonomoto

Journal of Applied Microbiology   109 ( 1 )   282 - 291   2010年7月

Functional significance of the E loop, a novel motif conserved in the lantibiotic immunity ATP-binding cassette transport systems. 査読 国際誌

Ken-ichi Okuda, Sae Yanagihara, Tomomichi Sugayama, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Journal of bacteriology   192 ( 11 )   2801 - 2808   2010年6月

Characterization of modification enzyme NukM and engineering of a novel thioether bridge in lantibiotic nukacin ISK-1. 査読 国際誌

Kouki Shioya, Yoshitaka Harada, Jun-ichi Nagao, Jiro Nakayama, Kenji Sonomoto

Applied microbiology and biotechnology   86 ( 3 )   891 - 899   2010年4月

Cell-to-cell communications among microorganisms

Sueharu Horinouchi, Kenji Ueda, Jiro Nakayama, Tsukasa Ikeda

Comprehensive Natural Products II: Chemistry and Biology   4   283 - 337   2010年3月

Effect of a negatively charged lipid on membrane-lacticin Q interaction and resulting pore formation 査読

Fuminori Yoneyama, Kouki Shioya, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   74 ( 1 )   218 - 221   2010年2月

Adiponectin and testosterone in patients with symptoms of late-onset hypogonadism: Is there a link? 査読

Akira Tsujimura, Shingo Takada, Yasuhiro Matsuoka, Jiro Nakayama, Tetsuya Takao, Yasushi Miyagawa, Mina Sonoda, Hitoshi Nishizawa, Hiromi Iwahashi, Tohru Funahashi, Norio Nonomura, Akihiko Okuyama

INTERNATIONAL JOURNAL OF UROLOGY   16 ( 10 )   830 - 835   2009年10月

Mapping and identification of the region and secondary structure required for the maturation of the nukacin ISK-1 prepeptide. 査読 国際誌

Jun-Ichi Nagao, Yoshiko Morinaga, Mohammad R Islam, Sikder M Asaduzzaman, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

Peptides   30 ( 8 )   1412 - 1420   2009年8月

Peptide-lipid huge toroidal pore, a new antimicrobial mechanism mediated by a lactococcal bacteriocin, lacticin Q. 査読 国際誌

Fuminori Yoneyama, Yuichi Imura, Kanako Ohno, Takeshi Zendo, Jiro Nakayama, Katsumi Matsuzaki, Kenji Sonomoto

Antimicrobial agents and chemotherapy   53 ( 8 )   3211 - 3217   2009年8月

Nukacin ISK-1, a bacteriostatic lantibiotic. 査読 国際誌

Sikder M Asaduzzaman, Jun-ichi Nagao, Hiroshi Iida, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Antimicrobial agents and chemotherapy   53 ( 8 )   3595 - 8   2009年8月

Evaluation of essential and variable residues of nukacin ISK-1 by NNK scanning 査読

Mohammad R. Islam, K. Shioya, J. Nagao, M. Nishie, H. Jikuya, T. Zendo, J. Nakayama, K. Sonomoto

Molecular Microbiology   72 ( 6 )   1438 - 1447   2009年6月

TRANSPLANTATION OF OLFACTORY MUCOSA FOLLOWING SPINAL CORD INJURY IMPROVES VOIDING EFFICIENCY IN RAT 査読

Jiro Nakayama, Keisuke Yamamoto, Shinichiro Fukuhara, Toshiaki Hirai, Tomohiro Ueda, Hiroshi Kiuchi, Tetsuya Takao, Yasushi Miyagawa, Akira Tsujimura, Akihiko Okuyama

JOURNAL OF UROLOGY   181 ( 4 )   337 - 337   2009年4月

Identification and characterization of lactocyclicin Q, a novel cyclic bacteriocin produced by Lactococcus sp. strain QU 12. 査読 国際誌

Naruhiko Sawa, Takeshi Zendo, Junko Kiyofuji, Koji Fujita, Kohei Himeno, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   75 ( 6 )   1552 - 1558   2009年3月

Two-peptide bacteriocin from Lactobacillus plantarum PMU 33 strain isolated from som-fak, a Thai low salt fermented fsh product

W. Noonpakdee, P. Jumriangrit, K. Wittayakom, J. Zendo, J. Nakayama, K. Sonomoto, S. Panyim

Asia-Pacific Journal of Molecular Biology and Biotechnology   17 ( 1 )   19 - 25   2009年1月

Two-peptide bacteriocin from Lactobacillus plantarum PMU 33 strain isolated from som-fak, a Thai low salt fermented fsh product

W. Noonpakdee, P. Jumriangrit, K. Wittayakom, J. Zendo, J. Nakayama, K. Sonomoto, S. Panyim

Asia-Pacific Journal of Molecular Biology and Biotechnology   17 ( 1 )   19 - 25   2009年1月

Lacticin Q, a lactococcal bacteriocin, causes high-level membrane permeability in the absence of specific receptors. 査読 国際誌

Fuminori Yoneyama, Yuichi Imura, Shiro Ichimasa, Koji Fujita, Takeshi Zendo, Jiro Nakayama, Katsumi Matsuzaki, Kenji Sonomoto

Applied and environmental microbiology   75 ( 2 )   538 - 541   2009年1月

Biosynthetic characterization and biochemical features of the third natural nisin variant, nisin Q, produced by Lactococcus lactis 61-14 査読

F. Yoneyama, M. Fukao, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Journal of Applied Microbiology   105 ( 6 )   1982 - 1990   2008年12月

Two homologous Agr-like quorum-sensing systems cooperatively control adherence, cell morphology, and cell viability properties in Lactobacillus plantarum WCFS1. 査読 国際誌

Toshio Fujii, Colin Ingham, Jiro Nakayama, Marke Beerthuyzen, Ryoko Kunuki, Douwe Molenaar, Mark Sturme, Elaine Vaughan, Michiel Kleerebezem, Willem de Vos

Journal of bacteriology   190 ( 23 )   7655 - 65   2008年12月

Biosynthetic characterization and biochemical features of the third natural nisin variant, nisin Q, produced by Lactococcus lactis 61-14 査読

F. Yoneyama, M. Fukao, T. Zendo, J. Nakayama, K. Sonomoto

Journal of Applied Microbiology   105 ( 6 )   1982 - 1990   2008年12月

Binding specificity of the lantibiotic-binding immunity protein NukH. 査読 国際誌

Ken-ichi Okuda, Sae Yanagihara, Kouki Shioya, Yoshitaka Harada, Jun-ichi Nagao, Yuji Aso, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   74 ( 24 )   7613 - 7619   2008年12月

Identification and partial characterization of pediocin PA-1 producing Pediococcus pentosaceus associated in traditional Thai fermented beef (mum) 査読

Adisorn Swetwiwathana, Yaowalak Surapantapisit, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

JOURNAL OF BIOTECHNOLOGY   136   S748 - S749   2008年10月

Description of durancin TW-49M, a novel enterocin B-homologous bacteriocin in carrot-isolated Enterococcus durans QU 49 査読

C. B. Hu, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Journal of Applied Microbiology   105 ( 3 )   681 - 690   2008年9月

Expression, purification and activities of the entire family of intact membrane sensor kinases from Enterococcus faecalis. 査読 国際誌

Molecular membrane biology   25 ( 6-7 )   449 - 473   2008年9月

Identification of the nukacin KQU-131, a new type-A(II) lantibiotic produced by Staphylococcus hominis KQU-131 isolated from Thai fermented fish product (Pla-ra). 査読 国際誌

Pongtep Wilaipun, Takeshi Zendo, Ken-ichi Okuda, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   72 ( 8 )   2232 - 2235   2008年8月

Complete covalent structure of nisin Q, new natural nisin variant, containing post-translationally modified amino acids. 査読 国際誌

Masanori Fukao, Takayuki Obita, Fuminori Yoneyama, Daisuke Kohda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   72 ( 7 )   1750 - 5   2008年7月

In vivo and in vitro complementation study comparing the function of DnaK chaperone systems from halophilic lactic acid bacterium Tetragenococcus halophilus and Escherichia coli. 査読 国際誌

Shinya Sugimoto, Kozue Saruwatari, Chihana Higashi, Keigo Tsuruno, Shunsuke Matsumoto, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   72 ( 3 )   811 - 22   2008年3月

Bacteriocin detection by liquid chromatography/mass spectrometry for rapid identification 査読

T. Zendo, J. Nakayama, K. Fujita, K. Sonomoto

Journal of Applied Microbiology   104 ( 2 )   499 - 507   2008年2月

Complete covalent structure of nisin Q, new natural nisin variant, containing post-translationally modified amino acids 査読

Masanori Fukao, Takayuki Obita, Fuminori Yoneyama, Daisuke Kohda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   72 ( 7 )   1750 - 1755   2008年1月

Cooperative transport between NukFEG and NukH in immunity against the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1. 査読 国際誌

Ken-ichi Okuda, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

Journal of bacteriology   190 ( 1 )   356 - 62   2008年1月

In vivo and in vitro complementation study comparing the function of DnaK chaperone systems from halophilic lactic acid bacterium Tetragenococcus halophilus and Escherichia coli 査読

Shinya Sugimoto, Kozue Saruwatari, Chihana Higashi, Keigo Tsuruno, Shunsuke Matsumoto, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   72 ( 3 )   811 - 822   2008年1月

Cooperative transport between NukFEG and NukH in immunity against the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1 査読

Ken Ichi Okuda, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

Journal of Bacteriology   190 ( 1 )   356 - 362   2008年1月

Characterization and structure analysis of a novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14 査読

Shun Iwatani, Takeshi Zendo, Fuminori Yoneyama, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   71 ( 8 )   1984 - 1992   2007年11月

Characterization, N-terminal sequencing and classification of cerein MRX1, a novel bacteriocin purified from a newly isolated bacterium: Bacillus cereus MRX1 査読

S. Sebei, T. Zendo, A. Boudabous, J. Nakayama, K. Sonomoto

Journal of Applied Microbiology   103 ( 5 )   1621 - 1631   2007年11月

Characterization, N-terminal sequencing and classification of cerein MRX1, a novel bacteriocin purified from a newly isolated bacterium Bacillus cereus MRX1 査読

S. Sebei, Takeshi Zendo, A. Boudabous, Jiro Nakayama, Kenji Sonomoto

Journal of Applied Microbiology   103 ( 5 )   1621 - 1631   2007年11月

Differences in developing intestinal microbiota between allergic and non-allergic infants: a pilot study in Japan. 査読 国際誌

Prapa Songjinda, Jiro Nakayama, Atsushi Tateyama, Shigemitsu Tanaka, Mina Tsubouchi, Chikako Kiyohara, Taro Shirakawa, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   71 ( 9 )   2338 - 42   2007年9月

Characterization and structure analysis of a novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14. 査読 国際誌

Shun Iwatani, Takeshi Zendo, Fuminori Yoneyama, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   71 ( 8 )   1984 - 92   2007年8月

A gram-negative characteristic segment in Escherichia coli DnaK is essential for the ATP-dependent cooperative function with the co-chaperones DnaJ and GrpE. 査読 国際誌

Shinya Sugimoto, Chihana Higashi, Kozue Saruwatari, Jiro Nakayama, Kenji Sonomoto

FEBS letters   581 ( 16 )   2993 - 2999   2007年6月

Structural analysis and characterization of lacticin Q, a novel bacteriocin belonging to a new family of unmodified bacteriocins of gram-positive bacteria. 査読 国際誌

Koji Fujita, Shiro Ichimasa, Takeshi Zendo, Shoko Koga, Fuminori Yoneyama, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   73 ( 9 )   2871 - 3877   2007年5月

Cooperative transport mechanism between NukFEG and NukH in immunity process against the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1 査読 国際誌

Okuda, K., Y. Aso, J. Nakayama, K. Sonomoto

J. Bacteriol.,   2007年1月

Maturation of Nahm ? a Thai fermented meat product. Effect of pediocin PA-1 producer (Pediococcus pentosaceus TISTR 536) as starter culture, nitrite and garlic on Salmonella anatum during Nham fermentation 査読 国際誌

Swetwiwathana, A., L. Napha, J. Nakayama, K. Sonomoto

Fleischwirtschaft International   22 ( 3 )   46 - 49   2007年1月

Structural and functional conversion of molecular chaperone ClpB from the gram-positive halophilic lactic acid bacterium Tetragenococcus halophilus mediated by ATP and stress 査読

Shinya Sugimoto, Hiroyuki Yoshida, Yoshimitsu Mizunoe, Keigo Tsuruno, Jiro Nakayama, Kenji Sonomoto

Journal of Bacteriology   188 ( 23 )   8070 - 8078   2006年12月

Structural and functional conversion of molecular chaperone ClpB from the gram-positive halophilic lactic acid bacterium Tetragenococcus halophilus mediated by ATP and stress. 査読 国際誌

Shinya Sugimoto, Hiroyuki Yoshida, Yoshimitsu Mizunoe, Keigo Tsuruno, Jiro Nakayama, Kenji Sonomoto

Journal of bacteriology   188 ( 23 )   8070 - 8   2006年12月

Lantibiotics: insight and foresight for new paradigm. 査読

Jun-ichi Nagao, Sikder M Asaduzzaman, Yuji Aso, Ken-Ichi Okuda, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   102 ( 3 )   139 - 49   2006年9月

Lysine-oriented charges trigger the membrane binding and activity of nukacin ISK-1. 査読 国際誌

Sikder M Asaduzzaman, Jun-Ichi Nagao, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   72 ( 9 )   6012 - 7   2006年9月

Lantibiotics: insight and foresight for new paradigm. 査読

Jun-ichi Nagao, Sikder M Asaduzzaman, Yuji Aso, Ken-Ichi Okuda, Jiro Nakayama, Kenji Sonomoto

Journal of bioscience and bioengineering   102 ( 3 )   139 - 49   2006年9月

Lysine-oriented charges trigger the membrane binding and activity of nukacin ISK-1 査読

Sikder M. Asaduzzaman, Jun Ichi Nagao, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

Applied and Environmental Microbiology   72 ( 9 )   6012 - 6017   2006年9月

Lactococcin Q, a novel two-peptide bacteriocin produced by Lactococcus lactis QU 4. 査読 国際誌

Takeshi Zendo, Shoko Koga, Yasushi Shigeri, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology   72 ( 5 )   3383 - 3389   2006年5月

Purification and amino acid sequence of a bacteriocins produced by Lactobacillus salivarius K7 isolated from chicken intestine

Komkhae Pilasombut, Thavajchai Sakpuaram, Worawidh Wajjwalku, Sunee Nitisinprasert, Adisorn Swetwiwathana, Takeshi Zendo, Koji Fujita, Jiro Nakayama, Kenji Sonomoto

Songklanakarin Journal of Science and Technology   28 ( SUPPL. 1 )   121 - 131   2006年3月

Identification and production of a bacteriocin from Enterococcus mundtii QU 2 isolated from soybean 査読

Takeshi Zendo, N. Eungruttanagorn, S. Fujioka, Yukihiro Tashiro, K. Nomura, Y. Sera, G. Kobayashi, Jiro Nakayama, A. Ishizaki, Kenji Sonomoto

Journal of Applied Microbiology   99 ( 5 )   1181 - 1190   2005年11月

Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli. 国際誌

Jun-Ichi Nagao, Yoshitaka Harada, Kouki Shioya, Yuji Aso, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Biochemical and biophysical research communications   336 ( 2 )   507 - 513   2005年10月

A novel type of immunity protein, NukH, for the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1 査読

Yuji Aso, Ken Ichi Okuda, Jun Ichi Nagao, Youhei Kanemasa, Nguyen Thi Bich Phuong, Hanako Koga, Kouki Shioya, Toshihiro Sashihara, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   69 ( 7 )   1403 - 1410   2005年9月

Characterization of functional domains of lantibiotic-binding immunity protein, NukH, from Staphylococcus warneri ISK-1. 査読 国際誌

Ken-ichi Okuda, Yuji Aso, Jun-ichi Nagao, Kouki Shioya, Youhei Kanemasa, Jiro Nakayama, Kenji Sonomoto

FEMS microbiology letters   250 ( 1 )   19 - 25   2005年9月

Localization and interaction of the biosynthetic proteins for the lantibiotic, nukacin ISK-1 査読

Jun Ichi Nagao, Yuji Aso, Toshihiro Sashihara, Kouki Shioya, Asaho Adachi, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   69 ( 7 )   1341 - 1347   2005年9月

Characterization of functional domains of lantibiotic-binding immunity protein, NukH, from Staphylococcus warneri ISK-1 査読

Ken Ichi Okuda, Yuji Aso, Jun Ichi Nagao, Kouki Shioya, Youhei Kanemasa, Jiro Nakayama, Kenji Sonomoto

FEMS Microbiology Letters   250 ( 1 )   19 - 25   2005年9月

A novel type of immunity protein, NukH, for the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1. 査読 国際誌

Yuji Aso, Ken-ichi Okuda, Jun-ichi Nagao, Youhei Kanemasa, Nguyen Thi Bich Phuong, Hanako Koga, Kouki Shioya, Toshihiro Sashihara, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   69 ( 7 )   1403 - 10   2005年7月

Localization and interaction of the biosynthetic proteins for the lantibiotic, Nukacin ISK-1. 査読 国際誌

Jun-ichi Nagao, Yuji Aso, Toshihiro Sashihara, Kouki Shioya, Asaho Adachi, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   69 ( 7 )   1341 - 7   2005年7月

Description of complete DNA sequence of two plasmids from the nukacin ISK-1 producer, Staphylococcus warneri ISK-1. 査読 国際誌

Yuji Aso, Hanako Koga, Toshihiro Sashihara, Jun-Ichi Nagao, Youhei Kanemasa, Jiro Nakayama, Kenji Sonomoto

Plasmid   53 ( 2 )   164 - 178   2005年3月

Molecular monitoring of the developmental bacterial community in the gastrointestinal tract of Japanese infants. 査読 国際誌

Prapa Songjinda, Jiro Nakayama, Yumiko Kuroki, Shigemitsu Tanaka, Sanae Fukuda, Chikako Kiyohara, Tetsuro Yamamoto, Kunio Izuchi, Taro Shirakawa, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   69 ( 3 )   638 - 41   2005年3月

Reconstitution and function of Tetragenococcus halophila chaperonin 60 tetradecamer. 査読

Amonlaya Tosukhowong, Jiro Nakayama, Yoshimitsu Mizunoe, Shinya Sugimoto, Daisuke Fukuda, Kenji Sonomoto

Journal of bioscience and bioengineering   99 ( 1 )   30 - 7   2005年1月

Characterization of a gene cluster of Staphylococcus warneri ISK-1 encoding the biosynthesis of and immunity to the lantibiotic, nukacin ISK-1. 国際誌

Yuji Aso, Toshihiro Sashihara, Jun-Ichi Nagao, Youhei Kanemasa, Hanako Koga, Taku Hashimoto, Toshimasa Higuchi, Asaho Adachi, Harumi Nomiyama, Ayaaki Ishizaki, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   68 ( 8 )   1663 - 1671   2004年8月

Heterologous expression and functional analysis of the gene cluster for the biosynthesis of and immunity to the lantibiotic, nukacin ISK-1 査読

Yuji Aso, Jun Ichi Nagao, Hanako Koga, Ken Ichi Okuda, Youhei Kanemasa, Toshihiro Sashihara, Jiro Nakayama, Kenji Sonomoto

Journal of Bioscience and Bioengineering   98 ( 6 )   429 - 436   2004年1月

The two-synergistic peptide bacteriocin produced by Enterococcus faecium NKR-5-3 isolated from Thai fermented fish (Plara). 査読 国際誌

Wilaipun, P., T. Zendo, M. Sangjindavong, S. Nitisinprasert, V. Leelawatcharamas, J. Nakayama, and K. Sonomoto

ScienceAsia   - 30   2004年1月

Nucleotide sequences of genes encoding allosamidin-sensitive and -insensitive chitinases produced by allosamidin-producing Streptomyces. 査読 国際誌

Hiroshi Matsuura, Susumu Okamoto, Sarintip Anamnart, Qiuqi Wang, Ze-Yang Zhou, Takuya Nihira, Yasuhiro Yamada, Tomohisa Kuzuyama, Haruo Seto, Jiro Nakayama, Akinori Suzuki, Hiromichi Nagasawa, Shohei Sakuda

Bioscience, biotechnology, and biochemistry   67 ( 9 )   2002 - 2005   2003年9月

Identification of the lantibiotic nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan. 査読 国際誌

Takeshi Zendo, Masanori Fukao, Kyoko Ueda, Tomoko Higuchi, Jiro Nakayama, Kenji Sonomoto

Bioscience, biotechnology, and biochemistry   67 ( 7 )   1616 - 9   2003年7月

Effect of heterologous expression of molecular chaperone DnaK from Tetragenococcus halophilus on salinity adaptation of Escherichia coli 査読

Shinya Sugimoto, Jiro Nakayama, Daisuke Fukuda, Shino Sonezaki, Maki Watanabe, Amonlaya Tosukhowong, Kenji Sonomoto

Journal of Bioscience and Bioengineering   96 ( 2 )   129 - 133   2003年1月

Identification of the lantibiotic nisin q, a new natural nisin variant produced by lactococcus lactis 61-14 isolated from a river in japan 査読

Takeshi Zendo, Masanori Fukao, Kyoko Ueda, Tomoko Higuchi, Jiro Nakayama, Kenji Sonomoto

Bioscience, Biotechnology and Biochemistry   67 ( 7 )   1616 - 1619   2003年1月

Aminoacylation of the N-terminal cysteine is essential for Lol-dependent release of lipoproteins from membranes but does not depend on lipoprotein sorting signals. 国際誌

Ayumu Fukuda, Shin-Ichi Matsuyama, Takashi Hara, Jiro Nakayama, Hiromichi Nagasawa, Hajime Tokuda

The Journal of biological chemistry   277 ( 45 )   43512 - 43518   2002年11月

Functional analysis of TraA, the sex pheromone receptor encoded by pPD1, in a promoter region essential for the mating response in Enterococcus faecalis. 国際誌

Takaaki Horii, Hiromichi Nagasawa, Jiro Nakayama

Journal of bacteriology   184 ( 22 )   6343 - 50   2002年11月

Blasticidin A as an inhibitor of aflatoxin production by Aspergillus parasiticus 査読

S. Sakuda, M. Ono, H. Ikeda, T. Nakamura, Y. Inagaki, R. Kawachi, Jiro Nakayama, A. Suzuki, A. Isogai, H. Nagasawa

Journal of Antibiotics   53 ( 11 )   1265 - 1271   2000年1月

Aflastatins: New streptomyces metabolites that inhibit aflatoxin biosynthesis

Shohei Sakuda, Makoto Ono, Hiroyuki Ikeda, Masaru Sakurada, Jiro Nakayama, Akinori Suzuki, Akira Isogai

Biologically Active Natural Products: Agrochemicals   185 - 200   1999年1月

Structures and biosynthesis of aflastatins: Novel inhibitors of aflatoxin production by Aspergillus parasiticus

Makoto Ono, Shohei Sakuda, Hiroyuki Ikeda, Kazuo Furihata, Jiro Nakayama, Akinori Suzuki, Akira Isogai

Journal of Antibiotics   51 ( 11 )   1019 - 1028   1998年11月

Molecular mechanism of peptide-specific pheromone signaling in Enterococcus faecalis: Functions of pheromone receptor TraA and pheromone- binding protein TraC encoded by plasmid pPD1 査読

Jiro Nakayama, Yuuichiro Takanami, Takaaki Horii, Shohei Sakuda, Akinori Suzuki

Journal of Bacteriology   180 ( 3 )   449 - 456   1998年2月

Structures and biosynthesis of aflastatins: novel inhibitors of aflatoxin production by Aspergillus parasiticus 査読

Makoto Ono, Shohei Sakuda, Hiroyuki Ikeda, Kazuo Furihata, Jiro Nakayama, Akinori Suzuki, Akira Isogai

Journal of Antibiotics   51 ( 11 )   1019 - 1028   1998年1月

Structure of blasticidin A 査読

Shohei Sakuda, Ono Makoto, Hiroyuki Ikeda, Yasuhito Inagaki, Jiro Nakayama, Akinori Suzuki, Akira Isogai

Tetrahedron Letters   38 ( 42 )   7399 - 7402   1997年10月

Genetic analysis of plasmid-specific pheromone signaling encoded by ppd1 in enterococcus faecalis 査読

Jiro Nakayama, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   61 ( 11 )   1796 - 1799   1997年1月

Aflastatin A, a novel inhibitor of aflatoxin production of Aspergillus parasiticus, from Streptomyces 査読

Shohei Sakuda, Makoto Ono, Kazuo Furihata, Jiro Nakayama, Akinori Suzuki, Akira Isogai

Journal of the American Chemical Society   118 ( 33 )   7855 - 7856   1996年8月

Isolation and Structure of staph-cAM373 Produced by Staphylococcus aureus That Induces Conjugal Transfer of Enterococcus faecalis Plasmid pAM373 査読

Liro Nakayama, Shigeru Igarashi, Hiromichi Nagasawa, Don B. Clewell, Florence Y. An, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   60 ( 6 )   1038 - 1039   1996年1月

Quantitative analysis for pheromone inhibitor and pheromone shutdown in Enterococcus faecalis. 査読

Jiro Nakayama, G. M. Dunny, D. B. Clewell, A. Suzuki

Developments in Biological Standardization   85   35 - 38   1995年1月

Structural Analysis of New Syringopeptins by Tandem Mass Spectrometry 査読

Akira Isogai, Akira Isogai, Jiro Nakayama, Jiro Nakayama, Akinori Suzuki, Akihiko Kusai, Jon Y. Takemoto

Bioscience, Biotechnology and Biochemistry   59 ( 7 )   1374 - 1376   1995年1月

Rotihibins, Novel Plant Growth Regulators from Streptomyces graminofaciens 査読

Naoyuki Fukuchi, Kazuo Furihata, Jiro Nakayama, Akira Isogai

Journal of Antibiotics   48 ( 9 )   1004 - 1010   1995年1月

Structure and stereochemistry of three phytotoxins, syringomycin, syringotoxin and syringostatin, produced by Pseudomonas syringae pv. syringae 査読

Naoyuka Fukuchi, Akira Isogai, Jiro Nakayama, Seiji Takayama, Shuichi Yamashita, Kazuo Suyama, Jon Y. Takemoto, Akinori Suzuki

Journal of the Chemical Society, Perkin Transactions 1   ( 9 )   1149 - 1157   1992年12月

Partial amino-acid sequence of ECP31, a carrot embryogenic-cell protein, and enhancement of its accumulation by abscisic acid in somatic embryos 査読

Tomohiro Kiyosue, Jiro Nakayama, Shinobu Satoh, Akira Isogai, Akinori Suzuki, Hiroshi Kamada, Hiroshi Harada

Planta   186 ( 3 )   337 - 342   1992年2月

Isolation and structural elucidation of syringostatins, phytotoxins produced by pseudomonas syringae pv. syringae lilac isolate 査読

Naoyuki Fukuchi, Akira Isogai, Jiro Nakayama, Seiji Takayama, Shuichi Yamashita, Kazuo Suyama, Akinori Suzuki

Journal of the Chemical Society, Perkin Transactions 1   ( 7 )   875 - 880   1992年1月

Structural Elucidation of Rotihibin B by Tandem Mass Spectrometry 査読

Naoyuki Fukuchi, Jiro Nakayama, Seiji Takayama, Akira Isogai, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   56 ( 7 )   1152 - 1153   1992年1月

Structural Elucidation of Minor Components of Peptidyl Antibiotic P168s (Leucinostatins) by Tandem Mass Spectrometry 査読

Akira Isogai, Jiro Nakayama, Seiji Takayama, Akinori Suzuki, Akihiko Kusai

Bioscience, Biotechnology and Biochemistry   56 ( 7 )   1079 - 1085   1992年1月

Expression of a Putative Precursor of Pheromone Biosynthesis Activating Neuropeptide-I (PBAN-I) of the Silkmoth, Bombyx mori, and Its Conversion to the Mature Peptide, PBAN-I 査読

Tsuyoshi Kawano, Hisato Kuniyoshi, Jiro Nakayama, Hiromichi Nagasawa, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   55 ( 7 )   1943 - 1945   1991年1月

Amino acid sequence of pheromone-inducible surface protein in Enterococcus faecalis, that is encoded on the conjugative plasmid pPD1 査読

Jiro Nakayama, Hiromich Nagasawa, Akira Isogai, Don B. Clewell, Akinori Suzuki

FEBS Letters   268 ( 1 )   245 - 248   1990年7月

Structure of Syringotoxin B, a Phytotoxin Produced by Citrus Isolates of Pseudomonas syringae pv. syringae 査読

Naoyuki Fukuchi, Akira Isogai, Jiro Nakayama, Akinori Suzuki

Bioscience, Biotechnology and Biochemistry   54 ( 12 )   3377 - 3379   1990年1月

Stucture of Demethylallosamidin as an Insect Chitinase Inhibitor 査読

Akira Isogai, Masahiro Sato, Shohei Sakuda, Jiro Nakayama, Akinori Suzuki

Agricultural and Biological Chemistry   53 ( 10 )   2825 - 2826   1989年10月

Microbial Biofilms

（ 担当： 共著）

Springer  2014年9月 

乳酸菌とビフィズス菌のサイエンス

山本憲二、中山二郎、他（ 担当： 共著）

京都大学学術出版会  2010年11月 

Comprehensive Natural Products II: Chemistry and Biologym, Cell-to-cell communications among microorganisms

Sueharu Horinouchi, Kenji Ueda, Jiro Nakayama, Tsukasa Ikeda（ 担当： 共著）

Elsevier  2010年3月 

Effect of garlic on lactic acid and bacteriocins production of bacteriocin-producing lactic acid bacteria associated in Nham (Thai fermented meat) during fermentation

Swetwiwathana A., Lotong N., Nakayama J., Sonomoto K.

52nd International Congress of Meat Science and Technology: Harnessing and exploiting global opportunities  2023年8月    （ ISBN:9789086865796, 9789086860104 ）

食品免疫学辞典

中山二郎（ 担当： 共著）

朝倉書店  2021年11月 

食品免疫学辞典

中山二郎（ 担当： 共著）

朝倉書店  2021年11月 

Biotechnological Applications of Quorum Sensing Inhibitors

Basit Yousuf, Keika Adachi, Jiro Nakayama（ 担当： 共著）

Springer Nature  2018年6月 

Quorum quenching strategy targeting gram-positive pathogenic bacteria

Ravindra Pal Singh, Said E. Desouky, Jiro Nakayama

Springer New York LLC  2016年1月 

Quorum Sensing vs Quorum Quenching: A Battle with no end in Sight (Development of quorum-sensing inhibitors targeting the fsr system of enterococcus faecalis)

Ravindra Pal Singh, Jiro Nakayama（ 担当： 共著）

Springer  2015年1月 

Quorum Sensing vs Quorum Quenching: A Battle with no end in Sight (Quorum-sensing systems in enterococci)

Ravindra Pal Singh, Jiro Nakayama（ 担当： 共著）

Springer  2015年1月 

環境と微生物の事典

中山二郎、他（ 担当： 共著）

朝倉書店  2014年5月 

世紀を越えるビフィズス菌の研究

上野川修一、山本憲二、中山二郎、他（ 担当： 共著）

(財）日本ビフィズス菌センター  2011年6月 

腸内共生系のバイオサイエンス

上野川修一、清野宏、中山二郎、他（ 担当： 共著）

丸善出版  2011年5月 

Cell-to-cell communications among microorganisms

Sueharu Horinouchi, Kenji Ueda, Jiro Nakayama, Tsukasa Ikeda

Elsevier Ltd  2010年3月 

医科プロバイオティクス学

中山二郎、他（ 担当： 共著）

シナジー  2009年1月 

プロバイオティクスとバイオジェニクス

中山二郎，田中重光，園元謙二（ 担当： 共著）

2005年1月 

Aflastatins New streptomyces metabolites that inhibit aflatoxin biosynthesis

Shohei Sakuda, Makoto Ono, Hiroyuki Ikeda, Masaru Sakurada, Jiro Nakayama, Akinori Suzuki, Akira Isogai

CRC Press  1999年1月 

Increase of non-communicable diseases in Asia is caused by change in diets and/or gut microbiota ? 招待 国際会議

Jiro Nakayama

The 13th Asian Conference on Lactic Acid Bacteria  2023年10月 

Crisis and Remodeling of Asian Gut Microbiome 招待 国際会議

Jiro Nakayama

The 8th International Conference of Indonesian Society for Lactic Acid Bacteria and Gut Microbiota  2023年7月 

炭素源の違いが合成腸内細菌叢に与える影響の解析

大石紗菜、中山二郎

第６０回化学関連支部合同大会  2023年7月 

各種海藻多糖類が腸内細菌叢に及ぼす影響の比較解析

太田匡俊、三島梨子、上野幹憲、中山二郎

日本農芸化学会2023年度大会  2023年3月 

直接作用型ウイルス剤(DAAs)による治療がC型肝炎患者の胆汁酸代謝に与える影響

中川大輔、井上貴子、田中靖人、中山二郎

日本農芸化学会2023年度大会  2023年3月 

人間ドック受診者を対象とした腸内細菌叢と代謝疾患との関連性の解析

田村史織、篠田あかり、井上貴子、渡辺久剛、田中靖人、中山二郎

日本農芸化学会2023年度大会  2023年3月 

Interaction of diet and gut microbiome in Asians and its effect on their health 招待

Jiro Nakayama

22nd International Union of Nutritional Sciences  2022年11月 

Asian Microbiome Project to understand the current status of gut microbial community of Asians as an interface between foods and health 招待

Jiro Nakayama

The 12th Asian Conference on Lactic Acid Bacteria  2022年10月 

Gut microbiome and metabolome of Asian population related to diet and health 招待

Jiro Nakayama

The 11th Asian Conference on Lactic Acid Bacteria  2021年11月 

Comparison of gut microbiota between diabetic and non-diabetic obese Mongolian 国際会議

Akari SHINODA, Shirchin DEMBEREL, Riko MISHIMA, Dugersuren JAMYAN, Tsogtbaatar LKHAGVAJAV , Jiro NAKAYAMA

The 11th Asian Conference on Lactic Acid Bacteria  2021年11月 

アジアの小学生児童の腸内細菌叢 招待

中山二郎

第25回腸 内細菌学会学術集  2021年6月 

各種ヒト胆汁酸による腸内芽胞形成細菌の発芽誘導と分離培養

鬼塚咲良，田中優，中山二郎

第25回腸 内細菌学会学術集会  2021年6月 

アジアの小学生児童の腸内細菌叢 招待

中山二郎

第25回腸 内細菌学会学術集会  2021年6月 

腸内環境および免疫機能に及ぼすあまおう乳酸菌およびフコイダンの摂食効果

篠田あかり，朴俊夏，中野勇人，柴崎哲哉， 宮﨑義之，中山二郎

日本農芸化学会2021年度大会  2021年3月 

日本人とインドネシア人の乳幼児の腸内メタゲノム比較解析

清野峻彦，堀野美里，田中優，山田拓司，林哲也， 後藤恭宏，加藤聖子，實藤雅文，諸隈誠一，小川昌宣， Endang Rahayu，中山 二郎

日本農芸化学会2021年度大会  2021年3月 

The succession of gut mycobiota in Japanese infants at first 3 years of life 国際会議

Riko Mishima, Masafumi Sanefuji, Seiichi Morokuma, Masaru Tanaka, Masanobu Ogawa, Kiyoko Kato, Jiro Nakayama

International Union of Microbiological Societies 2020  2020年10月 

アジア人の食と腸内フローラと生活習慣病 招待

中山二郎

Visionary 農芸化学100 シンポジウム 食・腸内細菌・健康研究領域 第3回シンポジウム「健康長寿社会に向けての腸内細菌科学の新展開  2021年9月 

生後1年間における乳幼児の腸内真菌叢形成と出産・育児環境因子の関連性解析

#三島 梨子、@實藤 雅文、@諸隈 誠一、#田中 優、百田 理恵、@園元 謙二、@小川 昌宣、@加藤 聖子、@中山 二郎

日本農芸化学会2019年度大会  2019年3月 

環状ペプチドクォルモンを介する腸内細菌と宿主のクロストークの可能性 招待

中山二郎

日本農芸化学会2019年度大会  2019年3月 

Maturation of the infant gut microbiota community and bile acids metabolism over three years in healthy Japanese infants 国際会議

7th Beneficial Microbes Conference  2018年11月 

Signatures imprinted in gut microbiome of Asians: a comparative metagenomic study of children in East and South-East Asia 国際会議

#Misato Horino, #M. Tanaka, #A. Uchikawa, R. Momoda, @K. Sonomoto, Y. Ogura, A. Toyoda, T. Yamada, K. Kurokawa, @T. Hayashi, @J.Nakayama

7th Beneficial Microbes Conference  2018年11月 

日本人成人における腸内細菌叢と食事の関連性の解析

内川彩夏，田中優, 余田美沙子，中山二郎, 池田温子, 河口礼佳, 十倉充範

日本農芸化学会 関西・中四国・西日本支部2017年度合同大阪大会  2017年9月 

Urbanization of Thai diets and its impacts to children gut microbiota and metabolites, The International Conference on Beneficial Microbes 国際会議

#J. Kisuse, #M. Tanaka, #P. Therdtatha, R. Momoda, O. La-ongkham, M. Nakphaichit, S. Nitisinpraser, S. Fukuda, @K. Sonomoto, @J. Nakayama

ICOBM2018  2018年8月 

アジア各国の腸内細菌叢の有する遺伝子機能に関する研究

堀野美里、田中優、内川彩夏、百田理恵、園元謙二、小椋義俊、豊田敦、山田拓司、黒川顕、林哲也、中山二郎

日本乳酸菌学会2018年度大会  2018年7月 

In vitro培養モデルを利用したヒト腸管における短鎖脂肪酸生産に関わる主要細菌群の選出

冬野憂介、安達 桂香、田中優、園元 謙二、中山 二郎

日本乳酸菌学会2018年度大会  2018年7月 

腸内細菌叢研究から見た日本人の食生活と健康：Asian Microbiome Projectの研究成果から 招待

中山二郎、Yuan-Kun Lee

第72回日本栄養・食糧学会大会  2018年5月 

日本人健常人の腸内細菌叢における胆汁酸代謝に関する研

余田美沙子、田中優、内川彩夏、百田理恵、池田温子、河口礼佳、園元謙二、十倉充範、中山二郎

日本農芸化学会2018年度大会  2018年3月 

日本人乳幼児の生後3年間の腸内フローラの形成・成熟化と胆汁酸代謝の関連性解析

田中優、實藤雅文、諸隈誠一、余田美沙子、百田理恵、園元謙二、加藤聖子、中山二郎

日本農芸化学会2018年度大会  2018年3月 

日本人健常成人の食と腸内細菌叢における短鎖脂肪酸の生産パターン

内川彩夏、田中優、余田美沙子、百田理恵、園元謙二、中山二郎、池田温子、河口礼佳、十倉充範

日本農芸化学会2018年度大会  2018年3月 

アジア人の腸内フローラとビフィズス菌 招待

中山二郎

腸内細菌と健康ービフィズス菌研究の新展開  2018年1月 

アジアマイクロビオームプロジェクト：アジア人の食と健康のインターフェースとしての腸内フローラの理解に向けて 招待

中山二郎

第26回腸内フローラシンポジウム  2017年10月 

Metabolic-linked pH-drop quenches VirSR quorum sensing in Clostridium perfringens 国際会議

Keika Adachi, Jiro Nakayama.

6th ASM Cell-Cell communication in Bacteria  2017年10月 

Ecology of gut microbiota in Japanese children - possible link with pre- and probiotics research 招待 国際会議

Jiro Nakayama

6th Beneficial Microbes Conference  2017年10月 

Clostridium perfringensの毒素生産制御に関わる内在性クオラムクエンチングの解析

安達桂香、Ravindra Pal Singh、園元謙二、中山二郎

第69回日本生物工学会年次大会  2017年9月 

Clostridium perfringensの代謝同調的な内在性クオラムクエンチング機構の実態解明

安達桂香、Ravindra Pal Singh、大谷郁、園元謙二、中山二郎

環境微生物系学会合同大会2017  2017年8月 

Changing dietary habit is changing Asians gut microbiota 招待 国際会議

Jiro Nakayama

15th International Congress of Bacteriology and Applied Microbiology  2017年7月 

健常成人における胆汁酸プロファイルと腸内細菌叢の関連性の解析

余田美沙子、田中優、内川彩夏、本田倫子、百田理恵、池田温子、河口礼佳、園元謙二、十倉充範、中山二郎

日本乳酸菌学会2017年度大会  2017年7月 

Clostridium perfringensの内在性クオラムクエンチング―代謝同調的pH低下によるクオラムセンシング機構の抑制―

安達桂香、神川美樹、Ravindra Pal Singh、大谷郁、園元謙二、中山二郎

日本農芸化学会  2017年3月 

Clostridiales目細菌ゲノムにコードされるagr様クオラムセンシング系自己誘導ペプチドのLC-MS/MS検出系の確率

中山二郎、神川美樹、安達桂香、大久保謙一、大谷郁、岡健太郎、園元謙二

日本農芸化学会  2017年3月 

腸内細菌叢研究の概論 招待

中山二郎

日本アレルギー学会イブニングシンポジウム  2016年12月 

ヒト腸内細菌叢のダイナミズムとダイバーシティー 招待

中山二郎

日本乳酸菌学会秋期セミナー  2016年12月 

Changing dietary habit is changing Asian gut microbiota 招待 国際会議

Jiro Nakayama

5th Beneficial Microbes Conference  2016年10月 

アジア人の腸内細菌叢 招待

中山二郎

Visonary農芸化学100シンポジウム  2016年10月 

アジア人の食と腸内細菌叢の関連性 招待

中山二郎、本田倫子、Kisuse Juma、百田理恵、田中優、園元謙二、Lee Yuan-Kun

日本生物工学会  2016年9月 

Clostridium butyricum MIYAIRI 588が産生するオートインデューサー様ペプチドの同定

神川美樹、庄島あかね、大久保謙一、松藤貴久、Ravindra Pal Siingh,　大谷郁、岡健太郎、高橋志達、園元謙二、中山二郎

第52回化学関連支部合同九州大会  2015年6月 

新生児の生後１年間の腸内細菌叢変化と食物アレルギー発症の関連性の解析

田中優、東佳那子、山本麻寿紗、本田倫子、百田理恵、清原千賀子、園元謙二、鷲尾昌一、中山二郎

第20回腸内細菌学会  2016年6月 

Development of quorum quenching peptides targeting VirR/VirS system of Clostridium perfringens 国際会議

Ravindra Pal Singh, Kenich Okubo, Kenji Sonomoto, Jiro Nakayama

6th Congress of European Microbiologists  2015年6月 

Clostridium perfringensの毒素産生を制御するクオラムクエンチングの機構の解明

安達桂香、大谷郁、河野通生、ラビンドラパルシン、園元謙二、中山二郎

日本農芸化学会2016年度大会  2016年3月 

食物アレルギー発症児と非発症児の乳幼児期における腸内細菌叢の比較解析

田中優、東佳那子、山本麻寿紗、本田倫子、百田理恵、清原千賀子、園元謙二、鷲尾昌一、中山二郎

日本農芸化学会2016年度大会  2016年3月 

フィリピンの子どもの腸内細菌叢：食との関連性

山本麻寿紗、本田倫子、田中優、百田理恵、Ladie Palermo, Jullie Tan, Yuan Kun Lee, 園元謙二、中山二郎

第22回日本生物工学会九州支部宮崎大会  2015年12月 

Clostridium perfringensの毒素産生を制御するクオラムクエンチングに関する研究

安達桂香、Ravindra Pal Singh,大谷郁、河野通生、園元謙二、中山二郎

第22回日本生物工学会九州支部宮崎大会  2015年12月 

Age-related changes and their food consumption affecting gut microbiota of healthy Thai subjects 招待 国際会議

Sunee Nitisinprasert, Orawan La-ongkam, Supatjaree Ruengsomwong, Massalin Nakphaichit, Bhusita Wanissorn, Jiro Nakayama

2015年10月 

新生児期における腸内細菌叢に影響を与える要因の網羅的解析

本田倫子、實藤雅文、諸隈誠一、山本麻寿紗、田中優、百田理恵、高木愛子、佐藤匡夫、月森清巳、加藤聖子、原寿郎、中山二郎

第67回日本生物工学会  2015年10月 

フィリピン都市部と農村部に住む児童の腸内細菌叢の比較

山本麻寿紗、本田倫子、田中優、百田理恵、Ladie Palermo, Jullie Tan, Yuan Kun Lee, 園元謙二、中山二郎

2015年度日本農芸化学会中四国・西日本支部合同大会  2015年9月 

Digging into our gut microbial community by NGS 招待 国際会議

Jiro Nakayama

2nd Asian Fermented Foods: Probiotic: the potential ingredients for health products  2015年8月 

What is microbiota, microbiome and their analysis ? 招待 国際会議

Jiro Nakayama

The 8th Asian Conference on Lactic Acid Bacteria  2015年7月 

アジア人の食と腸内細菌と健康に関するマルチコホート研究 招待

中山二郎

第19回腸内細菌学会  2015年6月 

Asian Microbiome Project:アジア人の食と腸内フローラと健康に関する調査研究 招待

中山二郎、渡辺幸一、Yuan-Kun Lee

日本農芸化学会2014年度大会  2014年3月 

放線菌の生産する環状デプシペプチドによるクオラムセンシング阻害活性

庄島あかね, 園元謙二, 中山二郎, Said E Desouky, 大久保謙一

日本農芸化学会2014年度大会  2014年3月 

アジア人の腸内フローラに見られる２つのエンテロタイプと地域特異性

東佳那子、Jiahui Jiang, 渡辺幸一、Shirchin Demberel, Sunee Nitisinprasert, Yongha Park, Endang S, Rahayum, Fa-Zheng Ren, Ying-Chieh Tsai, 園元謙二、Yuan-Kun Lee, 中山二郎

日本農芸化学会2014年度大会  2014年3月 

微生物二次代謝産物を対象としたグラム陽性病原細菌のクオラムセンシング阻害物質の探索

松藤貴久, 園元謙二, 中山二郎, Said E Desouky

第20回生物工学会九州支部佐賀大会  2013年12月 

Diversity in gut bacterial composition and their 16S rRNA gene sequences among Asian children

Jihaui Jiang, Kenji Sonomoto, Jiro Nakayama

2013年9月 

グラム陽性日和見感染菌のクオラムセンシング阻害剤のスクリーニングと構造解析

庄島あかね, 園元謙二, 中山二郎, 松藤貴久

第50回科学関連合同支部九州大会  2013年7月 

アジア５ヶ国児童の腸内細菌叢解析

第17回腸内細菌学会  2013年6月 

Phase I study of Asian Microbiome Project: Discovery of intestinal microbiota in Asian youngsters profiled bu 16S rRNA gene pyrosequencing

Jiang J, Nakayama J, Watanabe K, Sakamoto N, Matsuda K, Kurakawa T, Tsuji H, Ren FZ, Nitisinprasert S, Rahayu ES, Liao CC, Tsai YC, Lee YK

2013年3月 

腸内細菌と健康：ゆりかごから墓場まで 招待

中山二郎

日本微生物連盟フォーラム「驚きの微生物たち」  2013年1月 

腸球菌のクオラムセンシング阻害剤ZBzl-YAA5911の創製とその抗感染症剤としての効果検証

中山二郎，横畑綾治，松藤貴久，鈴木崇，永田宏次，園元謙二

第35回日本分子生物学会  2012年12月 

長期熟成糠床に生息する2つの乳酸桿菌のゲノム・生理特性解析

加唐圭太、阪本直茂、森一樹、田代康介、園元謙二、中山二郎

第19回九州支部大分大会  2012年6月 

454 Pyrosequencing study on the basal microbiota of healthy Asian youngsters 国際会議

Jiang J, Nakayama J, Watanabe K, Sakamoto N, Matsuda K, Kurakawa T, Tsuji H, Ren FZ, Nitisinprasert S, Rahayu ES, Liao CC, Tsai YC, Lee YK

3rd Asain Symposium on Lactic Acid Bacteria  2012年5月 

分子疫学研究による乳幼児腸内細菌叢とアレルギーの関連性の解析

田中 重光、SONGJINDA, Prapa、立山 敦、坪内 美樹、清原 千香子、白川 太郎、中山 二郎、園元 謙二

日本農芸化学会  2006年3月 

腸球菌のfsr系を制御する環状ペプチドGBAPの構造活性相関

西口 賢三、中山 二郎、園元 謙二

日本農芸化学会  2006年3月 

リステリア属細菌のagr様遺伝子群にコードされる環状ペプチドクォルモンの構造決定

朱雀 奈津子、西口 賢三、善藤 威史、中山 二郎、園元 謙二

日本農芸化学会  2008年3月 

腸球菌のクォーラムセンシングを制御する環状ペプチドクォルモン（GBAP）の2つの芳香族アミノ酸は受容体への結合に関与する

西口 賢三、中山 二郎1、永田 宏次、田之倉 優、園元 謙二

日本農芸化学会  2008年3月 

糸状菌二次代謝産物を対象とした腸球菌のクォーラムセンシング阻害物質の探索

上村 結美、中山 二郎、五十嵐 康弘、西口 賢三、園元 謙二

日本農芸化学会  2008年3月 

乳幼児における腸内細菌叢形成とアレルギー発症に関する研究

田中 重光、中山 二郎、SONGJINDA, Prapa、立山 敦、小林 貴子、清原 千香子、園元 謙二

日本農芸化学会  2008年3月 

AN OVERVIEW OF LACTOBACILLUS REUTERI KUB-AC5 AS AN ANTIMICROBIAL SUBSTANCE PRODUCER AND PROBIOTIC 招待 国際会議

Sunee Nitisinprasert, Massalin Nakphaichit, Nuntaporn Pungsungvorn, Jiraporn Tangthong, Arpa Suwatwattanakul, Jiro Nakayama, Kenji Sonomoto

International Union of Microbiological Societies 2011 Congress  2011年9月 

ASIAN MICROBIOME PROJECT 招待 国際会議

Yuan Kun Lee, Jiro Nakayama, Fazheng Ren, Sunee Nitisinprasert, Endang Rahayu, Raha Abdul Rahim, Chii Cherng Liao, Koichi Watanabe, Ying Chieh Tsai

International Union of Microbiological Societies 2011 Congress  2011年9月 

COMMUNITY STRUCTURE AND IMMUNE FUNCTION OF DEVELOPMENTAL GI TRACT MICROBIOTA IN INFANTS 招待 国際会議

Jiro Nakayama

International Union of Microbiological Societies 2011 Congress  2011年9月 

COMMUNITY STRUCTURE AND IMMUNE FUNCTION OF DEVELOPMENTAL GI TRACT MICROBIOTA IN INFANTS 招待 国際会議

Jiro Nakayama

International Union of Microbiological Societies 2011 Congress  2011年9月 

Discovery and Development of Inhibitors Targeting Cyclic　Peptide-mediated Quorum Sensing in Gram-positive　Pathogens 招待 国際会議

2011年11月 

Asian Microbiome Project: A pilot study on the basal microbiota profile of healthy Asian youngsters 国際会議

Nakayama J, Watanabe K, Sakamoto N, Jiang J, Matsuda K, Kurakawa T, Tsuji H, Ren FZ, Nitisinprasert S, Rahayu ES, Liao CC, Tsai YC, Lee YK

International Human Microbiome Conference  2012年3月 

日本人成人腸内細菌叢の７クラスターの短鎖脂肪酸・胆汁酸代謝機能性と食生活習慣との関係性

田中優、余田美沙子、内川彩夏、百田理恵、園元謙二、池田 温子、河口礼佳、十倉充範、亀山恵司、中山二郎

日本乳酸菌学会  2019年7月 

Features and signatures in Asian microbiome: Crisis or adaptation ? 招待 国際会議

Jiro Nakayama

The 10th Asian Conference on Lactic Acid Bacteria  2019年8月 

アジア人の食習慣と腸内細菌叢と健康に関する研究 招待

中山二郎

第71回日本生物工学会大会  2019年9月 

出生・育児環境が乳幼児期の腸内真菌叢形成に及ぼす影響

三島梨子，實藤雅文，諸隈誠一，田中優，園元謙二，小川昌宣，加藤聖子, 中山二郎

日本農芸化学会2019年度西日本・中四国支部合同沖縄大会  2019年11月 

Association of diets with intestinal microbiome in Asians 招待 国際会議

Jiro Nakayama

The 7th Iternational Conference on Food Factors  2019年12月 

腸内細菌と口腔内細菌の胆汁酸耐性

船津結妃，田中 優，鬼塚咲良，中山二郎

第26回日本生物工学会九州支部長崎大会  2019年12月 

胆汁酸の発芽誘導活性を利用した腸内芽胞形成細菌の分離と同定

田中 優，鬼塚 咲良，船津 結妃，中山 二郎

第93回日本細菌学会総会  2020年2月 

Difference of Gut Microbial Metabolism among Indonesian Obese, Type 2 Diabetic, and Healthy Groups

Yayi Song, Phatthanaphong Therdtatha, Masaru Tanaka, Mariyatun Mariyatun, Miisaroh Almunifah, Nancy Eka Putri Manurung, Siska Indriarshi, Yuan-kun, Lee, Endang Sutriswati Rahayu, Jiro Nakayama

2020年3月 

Difference of Gut Microbial Community in Indonesian Obese, Type 2 Diabetic, and Healthy Groups

Phatthanaphong Therdtatha, Masaru Tanaka, Mariyatun Mariyatun, Miisaroh Almunifah, Nancy Eka Putri Manurung, Siska Indriarshi, Yuan-kun, Lee, Endang Sutriswati Rahayu, Jiro Nakayama

2020年3月 

モンゴル人の腸内フローラと生活習慣病との関係

篠田あかり、デンベレルシルチン、三島梨子、田中優、堀野美里、ジャムヤンドゴースレン, ラハクバジャウツォクトバートル、中山二郎

日本農芸化学会２０２０年度大会  2020年3月 

ヒト腸内芽胞形成細菌の各種胆汁酸による発芽誘導と分離培養

鬼塚咲良，田中　優，中山二郎

日本農芸化学会２０２０年度大会  2020年3月 

腸内フローラにおける胆汁酸代謝と健康と疾病について俯瞰する 招待

中山二郎、田中優、船津結妃

日本農芸化学会２０２０年度大会  2020年3月 

Peptide-mediated cell-cell communication in Gram-positive bacteria 招待 国際会議

Nakayama, J.

The XVth international symposium on gnotobiology  2005年7月