Neural stem cell-specific ITPA deficiency causes neural depolarization and epilepsy Reviewed International journal

Yuichiro Koga, Daisuke Tsuchimoto, Yoshinori Hayashi, Nona Abolhassani, Yasuto Yoneshima, Kunihiko Sakumi, Hiroshi Nakanishi, Shinya Toyokuni, Yusaku Nakabeppu

JCI Insight   5 ( 22 )   e140229   2020.11

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes. Reviewed

Naoki Haruyama, Sakumi Kunihiko, Atsuhisa Katogi, Daisuke Tsuchimoto, Gabriele De Luca, Margherita Bignami, Yusaku Nakabeppu

Progress in Neurobiology   2019.4

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain Reviewed

Takayuki Fujii, Ryo Yamasaki, Kyoko Iinuma, Daisuke Tsuchimoto, Yoshinori Hayashi, Ban yu Saitoh, Takuya Matsushita, Mizuho A. Kido, Shinichi Aishima, Hiroshi Nakanishi, Yusaku Nakabeppu, Jun ichi Kira

Annals of Neurology   84 ( 2 )   208 - 224   2018.8

2-Oxoadenosine induces cytotoxicity through intracellular accumulation of 2-oxo-ATP and depletion of ATP but not via the p38 MAPK pathway Invited Reviewed International journal

Shinji Asada, Eiko Ohta, Yoriko Akimoto, ABOLHASSANI NONA, Daisuke Tsuchimoto, Yusaku Nakabeppu

SCIENTIFIC REPORTS   7   2017.7

Deficiency of the base excision repair enzyme NEIL3 is associated with increased lymphocyte apoptosis, autoantibodies and predisposition to autoimmunity. Reviewed International journal

M Massaad, J Zhou, Daisuke Tsuchimoto, J Chou, H Jabara, E Janssen, S Glauzy, B Olson, H Morbach, T Ohsumi, K Schmitz-Abe, M Kyriacos, J Kane, Kumiko Torisu, Yusaku Nakabeppu, LD Notarangelo, E Chouery, A Megarbane, PB Kang

The Journal of Clinical Investigation   in press   2016.10

PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice Reviewed International journal

2016.10

Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells. Reviewed International journal

Yasuto Yoneshima, Nona Abolhassani, Teruaki Iyama, Kunihiko Sakumi, Naoko Shiomi, Masahiko Mori, Tadahiro Shiomi, Tetsuo Noda, Daisuke Tsuchimoto, Yusaku Nakabeppu

Scientific Reports   6   32849   2016.9

MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death Reviewed International journal

Oncogenesis   2014.8

Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia. Reviewed International journal

Hiroko Nomaru, SAKUMI Kunihiko, Atsuhisa Katogi, Yoshinori N. Ohnishi, Kosuke Kajitani, Daisuke Tsuchimoto, Eric J. Nestler, Yusaku Nakabeppu

Glia   62 ( 8 )   1284 - 1298   2014.8

Apurinic/Apyrimidinic Endonuclease 2 Regulates the Expansion of Germinal Centers by Protecting against Activation-Induced Cytidine Deaminase-Independent DNA Damage in B Cells. Reviewed International journal

Jeroen E. J. Guikema, Erin K. Linehan, Nada Esa, Daisuke Tsuchimoto, Yusaku Nakabeppu, Robert T. Woodland, Carol E. Schrader

The Journal of Immunology   2014.6

Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation Reviewed International journal

Janet Stavnezer, Erin K. Linehan, Mikayla R. Thompson, Ghaith Habboub, Anna J. Ucher, Tatenda Kadungure, Daisuke Tsuchimoto, Yusaku Nakabeppu, Carol E. Schrader

Proceedings of the National Academy of Sciences of the United States of America   2014.6

8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair Reviewed

Zijing Sheng, Sugako Oka, Daisuke Tsuchimoto, Nona Abolhassani, Hiroko Nomaru, SAKUMI Kunihiko, Hideaki Yamada, Yusaku Nakabeppu

The Journal of Clinical Investigation   122 ( 12 )   4344 - 4361   2012.12

AP-Endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge. Reviewed International journal

Jeroen E.J. Guikema, Rachel M. Gerstein, Erin K. Linehan, Erin K. Clohert, Eric Evan-Browning, Daisuke Tsuchimoto, Yusaku Nakabeppu, and Carol E. Schrader

Journal of Immunology   186(4)   2011.2

Cancer-related PRUNE2 protein is associated with nucleotides and is highly expressed in mature nerve tissues. Reviewed International journal

Iwama E., Tsuchimoto D., Iyama T., Sakumi K., Nakagawara A., Takayama K., Nakanishi Y., and Nakabeppu Y.

Journal of Molecular Neuroscience   2011.1

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest. Reviewed International journal

Iyama T, Abolhassani N, Tsuchimoto D, Nonaka M, Nakabeppu Y.

Nucleic Acids Research   38(14)   2010.8

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals. Reviewed International journal

Abolhassani N, Iyama T, Tsuchimoto D, Sakumi K, Ohno M, Behmanesh M, Nakabeppu Y.

Nucleic Acids Res.   2010.5

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes Reviewed International journal

Sabouri Z, Okazaki IM, Shinkura R, Begum N, Nagaoka H, Tsuchimoto D, Nakabeppu Y, Honjo T

Int. Immunol.   2009.8

ITPase-deficient mice show growth retardation and die before weaning Reviewed International journal

Behmanesh M, Sakumi K, Abolhassani N, Toyokuni S, Oka S, Ohnishi YN, Tsuchimoto D, Nakabeppu Y

Cell Death and Differentiation   2009.6

Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine. Reviewed International journal

Nonaka M, Tsuchimoto D, Sakumi K, Nakabeppu Y.

FEBS J.   2009.3

Galectin-1 promotes basal and kainate-induced proliferation of neural progenitors in the dentate gyrus of adult mouse hippocampus. Reviewed International journal

Kajitani K, Nomaru H, Ifuku M, Yutsudo N, Dan Y, Miura T, Tsuchimoto D, Sakumi K, Kadoya T, Horie H, Poirier F, Noda M, Nakabeppu Y.

Cell Death Differ.   2009.3

Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus. Reviewed International journal

Dan Y, Ohta Y, Tsuchimoto D, Ohno M, Ide Y, Sami M, Kanda T, Sakumi K, Nakabeppu Y.

DNA Repair (Amst)   2008.9

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death Reviewed International journal

Ichikawa J, Tsuchimoto D, Oka S, Ohno M, Furuichi M, Sakumi K, Nakabeppu Y

DNA Repair   2008.3

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. Reviewed International journal

Oka S, Ohno M, Tsuchimoto D, Sakumi K, Furuichi M, Nakabeppu Y

The EMBO Journal   2008.1

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination Reviewed International journal

Guikema JEJ, Kinehan EK, Tsuchimoto D, Nakabeppu Y, Strauss PR, Stavnezer J, and Schrader CE

The Journal of Experimental Medicine   2007.11

A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single-nucleotide polymorphism in the human genome. Reviewed International journal

Ohno M., Miura T., Furuichi M., Tominaga Y., Tsuchimoto D., Sakumi K. and Nakabeppu Y.

Genome Research   2006.5

Hematopoietic tissue-specific expression of mouse Neil3 for Endonuclease VIII-like protein. Reviewed International journal

Torisu K., Tsuchimoto D., Ohnishi Y. and Nakabeppu Y.

The Journal of Biochemistry   138 ( 6 )   763 - 772   2005.12

Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome. Reviewed International journal

Behmanesh B., Sakumi K., Tsuchimoto D., Torisu K., Ohnishi-Honda Y., Rancourt D.E. and Nakabeppu Y.

DNA Research   12 ( 1 )   39 - 51   2005.2

A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA. Reviewed International journal

Ushijima Y., Tominaga Y, Miura T, Tsuchimoto D, Sakumi K and Nakabeppu Y.

Nucleic Acids Research   33 ( 2 )   672 - 682   2005.1

Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice. Reviewed International journal

Ide Y, Tsuchimoto D, Tominaga Y, Nakashima M, Watanabe T, Sakumi K, Ohno M, Nakabeppu Y.

Blood   104 ( 13 )   4097 - 4103   2004.12

A Mechanism of Transcriptional Regulation of the CSF-1 Gene by Interferon-gamma. Reviewed International journal

Tsuchimoto D, Tojo A, Asano S

Immunological Investigations   33 ( 4 )   397 - 405   2004.12

Galectin-1beta, a natural monomeric form of galectin-1 lacking its six amino-terminal residues promotes axonal regeneration but not cell death Reviewed International journal

Miura T, Takahashi M, Horie H, Kurushima H, Tsuchimoto D, Sakumi K, Nakabeppu Y.

Cell Death and Differentiation   11 ( 10 )   1076 - 1083   2004.10

MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain Reviewed International journal

Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano S, Sakumi K, Nakabeppu Y.

Nucleic Acids Research   32 ( 10 )   3198 - 3211   2004.6

Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: from mitochondria to nuclei International journal

Nakabeppu Y, Tsuchimoto D, Ichinoe A, Ohno M, Ide Y, Hirano S, Yoshimura D, Tominaga Y, Furuichi M, Sakumi K.

Ann N Y Acad Sci.   1011   101 - 111   2004.4

Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts Reviewed International journal

Ichinoe A, Behmanesh M, Tominaga Y, Ushijima Y, Hirano S, Sakai Y, Tsuchimoto D, Sakumi K, Wake N, Nakabeppu Y.

Nucleic Acids Research   32 ( 2 )   477 - 487   2004.1

Mutator phenotype of MUTYH-null mouse embryonic stem cells. Reviewed International journal

Hirano S, Tominaga Y, Ichinoe A, Ushijima Y, Tsuchimoto D, Honda-Ohnishi Y,

J Biol Chem.   278 ( 40 )   38121 - 38124   2003.10

DeltaFosB, but not FosB, induces delayed apoptosis independent of cell proliferation in the Rat1a embryo cell line. Reviewed International journal

Tahara K, Tsuchimoto D, Tominaga Y, Asoh S, Ohta S, Kitagawa M, Horie H, Nakabeppu Y

Cell Death Differ.   10 ( 5 )   496 - 507   2003.5

Characterization of the genomic structure and expression of the mouse Apex2 gene. Reviewed International journal

Ide Y, Tsuchimoto D, Tominaga Y, Iwamoto Y, Nakabeppu Y.

Genomics   81 ( 1 )   47 - 57   2003.1

Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen. Reviewed International journal

Tsuchimoto D, Sakai Y, Sakumi K, Nishioka K, Sasaki M, Fujiwara T, Nakabeppu Y

Nucleic Acids Res.   29 ( 11 )   2349 - 2360   2001.6

ITPA欠損によるヒトてんかん性脳症のモデルとしての神経幹細胞特異的Itpaノックアウトマウス

土本　大介、古賀　祐一郎、林　良憲、アボルハッサニ　ノナ、米嶋　康臣、@中西　博、中別府　雄作

第４１回日本日本分子生物学会年会  2018.11 

Neural stem cell-specific Itpa knockout mouse as a model of human epileptic encephalopathy caused by ITPA deficiency International conference

Daisuke Tsuchimoto, Yuichiro Koga, Yoshinori Hayashi, Nona Abolhassani,Yasuto Yoneshima, @Hiroshi Nakanishi, Yusaku Nakabeppu

The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018  2018.10 

Neural stem cell-specific Itpa knockout mouse as a model of human ITPA deficiency

Daisuke Tsuchimoto, #Yuichiro Koga, Yoshinori Hayashi, Nona Abolhassani, Yasuto Yoneshima, @Hiroshi Nakanishi, Yusaku Nakabeppu

2018.7 

イノシン三リン酸分解酵素ITPA欠損症のモデルマウス作製と解析

土本 大介, 古賀 祐一郎, 米嶋　康臣, 浅田　真司, 作見 邦彦, 中別府　雄作

平成28年度先端モデル動物支援プラットフォーム成果発表会  2017.2 

イノシン三リン酸分解酵素ITPA欠損の哺乳動物細胞およびマウス中枢神経系への影響の解析

土本 大介, 米嶋康臣, 古賀祐一郎, ABOLHASSANI NONA, 猪山 輝昭, 浅田真司, 作見 邦彦, 塩見尚子, 森雅彦, 塩見忠博, 野田哲生, 中別府　雄作

日本分子生物学会  2016.12 

イノシン三リン酸分解酵素ITPAの組織特異的欠損 マウス作成と解析

土本 大介, 古賀 祐一郎, 米嶋康臣, 浅田 真司, 中別府 雄作

日本分子生物学会／日本生化学会合同年会  2015.12 

デオキシイノシン三リン酸の蓄積はミスマッチ修復タンパク質MLH1に依存した細胞周期の遅延をもたらす

土本 大介, 米嶋 康臣, ABOLHASSANI NONA, 猪山 輝昭, 作見 邦彦, 塩見 尚子, 森 雅彦, 塩見 忠博, 野田 哲生, 中別府 雄作

日本分子生物学会総会  2014.11 

デオキシイノシン三リン酸の蓄積はミスマッチ修復機構に依存した細胞増殖抑制とゲノム不安定性を引き起こす

米嶋 康臣, 土本 大介, アボルハッサニ　ノナ, 猪山 輝昭, 作見 邦彦, 塩見 尚子, 森 雅彦, 塩見 忠博, 中別府 雄作

第36回日本分子生物学会年会、ポスター発表（2013年12月4日2P-0150）  2013.12 

2-OH-ATPによる細胞増殖抑制と細胞死に関与する遺伝子の網羅的解析

瀧口友香, 太田詠子, 土本 大介, 作見 邦彦, 中別府 雄作

日本遺伝学会第84回大会（演題番号2C-05)  2012.9 

イノシン三リン酸によるゲノム不安定化機構と細胞内イノシン三リン酸生成経路の解明

米嶋 康臣, 土本 大介, 作見 邦彦, 野田 哲生, 中別府 雄作

日本遺伝学会第84回大会（演題番号2E-02)  2012.9 

ほ乳動物細胞におけるデオキシイノシンヌクレオチドによるゲノム不安定化機構とその防御システム

土本大介、猪山輝昭、アボルハッサニ・ノナ、米嶋康臣、作見邦彦、塩見尚子、森雅彦、塩見忠博、中別府雄作

第34回日本分子生物学会年会  2011.12 

ほ乳動物細胞におけるデオキシイノシンヌクレオチドによるゲノム不安定化とその防御機構

土本大介、猪山輝昭、アボルハッサニ・ノナ、米嶋康臣、作見邦彦、中別府雄作

日本遺伝学会  2011.9 

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest International conference

Teruaki Iyama, Nona Abolhassani, Daisuke Tsuchimoto, Yusaku Nakabeppu

The 7th Global COE International Symposium and 6th Young Investigators Forum  2011.2 

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest International conference

Teruaki Iyama, Nona Abolhassani, Daisuke Tsuchimoto, Yusaku Nakabeppu

Keystone Symposia on Molecular and Cellular Biology, Genomic Instability and DNA Repair  2011.2 

NUDT16は（デオキシ）イノシン二リン酸分解酵素であり、その欠損は核DNAの一本鎖切断の蓄積と増殖抑制をもたらす

土本大介、猪山輝昭、アボルハッサニ　ノナ、野中麻里、中別府雄作

2010.12 

An increased expression of NUDT16 with IDP/dIDP hydrolyzing activity in immortalized ITPA-null mouse embryonic fibroblasts suppressed ITPA-deficient phenotypes

Nona Abolhassani, Teruaki Iyama, Daisuke Tsuchimoto, Kunihiko Sakumi, Mizuki Ohno, Behmanesh Mehrdad, Yusaku Nakabeppu

2009.12 

Human NUDT16 is a novel nucleotide pool sanitizing enzyme hydrolyzing (deoxy)inosine diphosphate to (deoxy)inosine monophosphate

Daisuke Tsuchimoto, Teruaki Iyama, Nona Abolhassani, Yusaku Nakabeppu

2009.12 

Human NUDT16 Is a Novel Nucleotide Pool Sanitizing Enzyme Hydrolyzing (Deoxy)Inosine Diphosphate to (Deoxy)Inosine Monophosphate.

Teruaki Iyama, Daisuke Tsuchimoto, Nona Abolhassani, Yusaku Nakabeppu

The 49th annual meeting of the American Society for Cell Biology  2009.12 

ヒトＮＵＤＴ１６は（デオキシ）イノシン二リン酸を（デオキシ）イノシン一リン酸に加水分解する新規ヌクレオチドプール浄化酵素である

土本大介、猪山輝昭、アボルハッサニ・ノナ、中別府雄作

第２０回DNA複製・組換え・修復ワークショップ  2009.11 

神経芽腫予後関連タンパク質Prune2の全長フォームの同定

土本大介、岩間映二、野中麻里、作見邦彦、中別府雄作

第32回日本神経科学大会  2009.9 

新規損傷ヌクレオチド浄化酵素ITPBP2の同定と機能解析

土本大介、猪山輝昭、吉田奈桜子、中別府雄作

2008.12 

新規cAMP phosphodiesteraseの同定と癌転移に関与する可能性の検討

岩間映二、土本大介、中別府雄作

2008.12 

Neil3遺伝子改変マウスにおける末梢白血球減少

土本大介，鳥巣久美子，中別府雄作

第２８回日本分子生物学会年会  2005.12 

ITP結合タンパク質ITPBP1の生化学的特性

野中麻里、土本大介、太田詠子、作見邦彦、中別府雄作

日本分子生物学会２００６フォーラム  2006.12 

ATP固定化樹脂を用いた損傷ヌクレオチド結合タンパク質の探索

土本大介、野中麻里、太田詠子、作見邦彦、中別府雄作

日本分子生物学会２００６フォーラム  2006.12 

ITP結合タンパク質ITPBP1の生物学的特性の解析

野中麻里、土本大介、太田詠子、作見邦彦、中別府雄作

日本分子生物学会  2007.12 

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest. International conference

Teruaki Iyama, Nona Abolhassani, Daisuke Tsuchimoto, Mari Nonaka, Yusaku Nakabeppu

The 7th 3R Symposium  2010.10 

Role of 8-oxoguanine accumulated in nuclear or mitochindrial DNA in the development of Alzheimer's disease

2016.12 

AP-1転写因子を構成するFosb遺伝子産物による 補体受容体遺伝子C5ar1発現制御機構の解析

森岡 紀子, 能丸 寛子, Julio Leon, 加藤木 敦央, 土本 大介, 作見 邦彦, 中別府 雄作

日本分子生物学会／日本生化学会合同年会  2015.12 

X線照射によるプリンヌクレオシド修飾の包括的 解析

秋本 頼子, ABOLHASSANI NONA, Erika Castillo, 土本 大介, 中別府 雄作

日本分子生物学会／日本生化学会合同年会  2015.12 

ヒトミトコンドリア型AP endonuclease 候補のcDNAクローニング

土本大介、中別府雄作

１９９８年第２１回日本分子生物学会年会  1998.12 

マウス新規AP endonuclease候補遺伝子APE2のクローニングと遺伝子欠損ES細胞株の樹立

井手康人，冨永洋平，土本大介，酒井康成，今磯泰幸，中別府雄作

２０００年第２３回日本分子生物学会年会  2000.12 

Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen.

Daisuke Tsuchimoto, Yusaku Nakabeppu

2001.12 

大腸菌Endonuclease VIII (Nei) 類似タンパク質NEIL3をコードする ヒトおよびマウス遺伝子のゲノム構造と発現解析

土本　大介、○鳥巣（中原）久美子、中別府　雄作

２００２年第２５回日本分子生物学会年会  2002.12 

MUTYH protects an intermediate of base excision repair by itself in DNA from a double-strand break caused by OGG1 and APEX1

2002.12 

Repair mechanism of misincorporated adenine opposite 8-oxoG by mammalian MutY homolog, MUTYH: its relevance to mutagenesis and carcinogenesis Invited

Daisuke Tsuchimoto, Yasuhiro Ushijima, Yohei Tominaga, Seiki Hirano, Akimasa Ichinoe, Kunihiko Sakumi, and Yusaku Nakabeppu

2003.10 

Establishment and characterization of APEX2 null mice International conference

Daisuke Tsuchimoto, Yasuhito Ide, Manabu Nakashima, Takeshi Watanabe and Yusaku Nakabeppu

2003.10 

APEX2欠損マウスの樹立とその解析

土本大介，井手康人，中島学，渡邊武，中別府雄作

２００３年第２６回日本分子生物学会年会  2003.12 

APEX2欠損マウスにおける抗オブアルブミン抗体産生の遅延

土本大介，井手康人，中島学，渡邊武，中別府雄作

第２７回日本分子生物学会年会  2004.12 

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals. International conference

Nona Abolhassani, Teruaki Iyama, Daisuke Tsuchimoto, SAKUMI Kunihiko, Ohno Mizuki, Mehrdad Behmanesh, Yusaku Nakabeppu

The 7th 3R Symposium  2010.10 

発達性てんかん性脳症の分子病態に迫る　マウスモデルを用いた早期乳児てんかん性脳症EIEE35の発症メカニズムの解明

土本 大介

脳と発達  2022.5  (一社)日本小児神経学会

ATPおよびGTPの酸化体による細胞内シグナル伝達機構の解明

Grant number：21117512  2009 - 2010

日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

マウスを用いたＤＮＡおよび遊離ヌクレオチドの品質管理機構欠損の分子病態解析

Grant number：19390114  2007 - 2009

日本学術振興会  科学研究費助成事業  基盤研究(B)

遺伝子改変マウスをモデルとしたＤＮＡ塩基除去修復欠損の分子病態解明

Grant number：16390119  2004 - 2006

日本学術振興会  科学研究費助成事業  基盤研究(B)

医科学ゼミナール

2021.4 - 2022.3   Full year

博士論文応用演習

2021.4 - 2022.3   Full year

細胞病理学

2021.4 - 2022.3   Full year

核酸と生命

2020.6 - 2020.8   Summer quarter

神経化学

2020.4 - 2021.3   Full year

行動生理

2020.4 - 2021.3   Full year

専攻コア統合科目「基礎医学研究者養成コース入門(1)-(4)」

2020.4 - 2021.3   Full year

総合医学 II ／総合生命科学 II （研究室配属）.

2020.4 - 2020.9   First semester

核酸と生命

2019.6 - 2019.8   Summer quarter

細胞病理学

2019.4 - 2020.3   Full year

遺伝子生化学

2019.4 - 2020.3   Full year

脳機能制御学研究法

2019.4 - 2020.3   Full year

分子神経科学

2019.4 - 2020.3   Full year

神経化学

2019.4 - 2020.3   Full year

行動生理

2019.4 - 2020.3   Full year

専攻コア統合科目「基礎医学研究者養成コース入門(1)-(4)」

2019.4 - 2020.3   Full year

総合医学 II ／総合生命科学 II （研究室配属）.

2019.4 - 2019.9   First semester

核酸と生命

2018.6 - 2018.8   Summer quarter

医科学ゼミナール

2018.4 - 2019.3   Full year

博士論文応用演習

2018.4 - 2019.3   Full year

細胞病理学

2018.4 - 2019.3   Full year

遺伝子生化学

2018.4 - 2019.3   Full year

遺伝子生化学

2017.4 - 2018.3   Full year

細胞病理学

2017.4 - 2018.3   Full year

医科学ゼミナール

2017.4 - 2018.3   Full year

博士論文応用演習

2017.4 - 2018.3   Full year

医科学ゼミナール（修士）

2016.4 - 2017.3   Full year

博士論文演習

2016.4 - 2017.3   Full year

専攻コア選択科目 「細胞病理学」

2016.4 - 2017.3   Full year

専攻コア選択科目 「遺伝子生化学」

2016.4 - 2017.3   Full year

基礎医学実習 「基礎医学研究者養成コース入門（１）〜（４）」

2016.4 - 2017.3   Full year

遺伝子生化学

2015.4 - 2016.3   Full year

細胞病理学

2015.4 - 2016.3   Full year

医科学ゼミナール

2015.4 - 2016.3   Full year

博士論文応用演習

2015.4 - 2016.3   Full year

2018.10   Role：Panelist   Title：平成３０年度馬出地区４部局合同男女共同参画FD

Organizer：[Undergraduate school/graduate school/graduate faculty]

2017.10   Role：Participation   Title：平成２９年度 部局男女共同参画FD(第一部：講演「無意識のバイアスからの開放：ダイバーシティのススメ」、第二部：公開討論会）

Organizer：[Undergraduate school/graduate school/graduate faculty]

2016.10   Role：Participation   Title：馬出地区キャンパスFD 「なぜ今『女性活躍推進法』か？ —男女共同参画の必要性と九州大学における取組み—」

Organizer：[Undergraduate school/graduate school/graduate faculty]

2007.4   Role：Participation   Title：平成19 年度第１回全学FD

Organizer：University-wide