Updated on 2025/08/13

Information

 

写真a

 
YOSHIHAMA NAOYA
 
Organization
Kyushu University Hospital Oral and Maxillofacial Surgery Assistant Professor
Graduate School of Dental Science （Concurrent）
Title
Assistant Professor
Homepage
External link

Research Areas

  • Life Science / Surgical dentistry

Degree

  • 歯学博士 （ 2014.3 Kyushu University ）

Research History

  • Kyushu University Section of Oral and Maxillofacial Surgery，Division of Maxillofacial Diagnostic and Surgical Sciences，Faculty of Dental Science Assistant Professor 

    2021.4 - Present

Education

  • Kyushu University   歯学部  

    2003.4 - 2009.3

Research Interests・Research Keywords

  • Research theme： jawbone reconstruction and dental implant

    Keyword： インプラント

    Research period： 2023.4 - Present

Papers

  • Oral metastatic tumor (renal cell carcinoma) in maxillary gingiva: A case report and systematic review

    Nakako, Y; Fujimoto, T; Wada, H; Yoshihama, N; Kami, Y; Fujii, S; Kohashi, K; Kumamaru, W; Chikui, T; Moriyama, M; Kiyoshima, T

    JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY   37 ( 4 )   839 - 848   2025.7   （ ISSN:2212-5558 eISSN:2212-5566 ）

    　More details

    Publisher：Journal of Oral and Maxillofacial Surgery Medicine and Pathology  

    Background and objective: Oral metastases are rare. We experienced a case of oral metastasis of renal cell carcinoma (RCC) and discussed its characteristics with a systematic review to survey the literature for useful features for the diagnosis of oral metastatic RCC. Methods: A systematic review was conducted according to the PRISMA 2020 statement. An electronic search was performed using three databases and the literature of cases of renal cancer metastasis to the jawbone and gingiva. Results: Thirty studies were identified (male-to-female ratio, 2.75:1). The site of metastasis was the jawbone in 66.7 % (mandible, 60 %; maxilla, 6.7 %) and the gingiva in 30 %. Clinical symptoms were a mass in 86.7 % and hypoesthesia in 23.3 %. A total of 76.7 % of oral metastases were clear cell type. In our case, the male patient showed a mass in the maxillary gingiva without hypoesthesia. Metastatic clear cell RCC was suspected by an oral biopsy, which was confirmed on clinical examinations, including a renal biopsy. Conclusion: Oral metastases are rare, and the clinical and imaging findings for oral metastases of RCC are wide-ranged with low specificity, depending on the metastatic site. It is necessary to fully understand the key points in histopathological differentiation. Because the clinician plays a fundamental role in the early diagnosis of oral cancer and the identification of metastatic lesions, awareness of the possibility of rare tumors as in this study can facilitate an accurate preoperative diagnosis and the planning of appropriate treatment.

    DOI： 10.1016/j.ajoms.2025.01.004

    Web of Science

    Scopus

  • 歯肉出血を契機に発見された後天性第X因子欠乏症の1例．

    日口外誌   2018.2

  • miR-203 Inhibits Frizzled-2 Expression via CD82/KAI1 Expression in Human Lung Carcinoma Cells. Reviewed

    PLoS One   2015.7

  • 唾石を伴った線維素性唾液管炎の1例.

    Hospital Dentistry & Oral-Maxillofacial Surgery   2015.6

  • 口腔内転移性腫瘍の2例

    Hospital Dentistry & Oral-Maxillofacial Surgery   2015.6

  • Knockdown of the T-box transcription factor Brachyury increases sensitivity of adenoid cystic carcinoma cells to chemotherapy and radiation in vitro: implications for a new therapeutic principle.

    Int J Oncol   2014.4

  • T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma.

    Int J Oncol   2012.12

  • Retrospective Study of Selective Submandibular Neck Dissection versus Radical Neck Dissection for N0 or N1 Necks in Level I Patients with Oral Squamous Cell Carcinoma.

    J Oncol   2012

▼display all

Books

  • 歯科診療・口腔ケアにおける救急＆アクシデント対応ハンドブック

    （Role：Joint author口腔ケア中のアクシデントに対する対応）

    医歯薬出版株式会社  2022.3 

Presentations

Professional Memberships

  • 日本口腔ケア学会

    2020.4 - Present

  • japanese society of oral and maxillofacial surgions

    2010.4 - Present

Educational Activities

  • 口腔外科および再生歯科インプラントセンター助教を併任していることから、口腔腫瘍に伴う顎骨切除後の再建とインプラントによる咬合再建に関する授業を担っている。また、口腔外科分野では学生臨床実習におけるadvancedOSCEのための実技実習および講義を担っている。
    臨床実習前のOSCEにおける予備実習も科内で分担制で担っている。

Class subject

  • 歯科補綴学

    2023.4 - Present  

Visiting, concurrent, or part-time lecturers at other universities, institutions, etc.

  • 2024  博多メディカル専門学校  Classification:Part-time lecturer  Domestic/International Classification:Japan 

Outline of Social Contribution and International Cooperation activities

  • We actively accept overseas observations related to implant treatment, and, provided that we obtain the patient's consent, we offer guided tours within the regenerative dental implant center and opportunities to observe surgeries.

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Dentistry / Surgical Dentistry

Clinician qualification

  • Certifying physician

    日本口腔外科学会

Year of medical license acquisition

  • 2009