Updated on 2025/05/01

Information

 

写真a

 
TOMOOKA SHOKO
 
Organization
Kyushu University Hospital General Dentistry Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス
Tel
0926426485
Profile
研究:地域一般住民を対象とした低濃度エンドトキシン血症と疾病の関連について疫学研究を継続中である。現在は血清LBPと脂肪肝ついての研究を行っている。 教育:歯学部学生の実習、歯科研修医の教育担当を行っている。 臨床:主に有病者、高齢者を対象に総合診療を行っている。また、摂食嚥下機能が低下した患者を対象として口腔リハビリテーションに関連した診療を行っている。

Degree

  • なし

Research Interests・Research Keywords

  • Research theme: Serum Lipopolysaccharide-binding Protein Levels and the Incidence of fatty liver in a General Japanese Population: the Hisayama Study.

    Keyword: Serum Lipopolysaccharide-binding Protein

    Research period: 2023.4 - 2025.3

Papers

  • An Investigation of the Effect of Clinical Practice during the COVID-19 Pandemic on Dental Studentsʼ Attitudes toward Older Adults

    Tomooka Shoko, Mizutani Shinsuke, Tabuchi Hiroaki, Oku Saori, Inoue Ryosuke, Yamazoe Junichi, Iwasa Yasuyuki, Kashiwazaki Haruhiko

    Ronen Shika Igaku   39 ( 3 )   162 - 170   2024.12   ISSN:09143866 eISSN:18847323

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    Language:Japanese   Publisher:Japanese Society of Gerodontology  

    <p> Japan has one of the worldʼs highest rates of population aging. Therefore, it is necessary for dentists to acquire a broad understanding of older adults. They are also required to learn to interact with older adults through gerodontology clinical practice and homebound dentistry practice. However, several students could not receive such training due to the COVID-19 pandemic. Therefore, this study aimed to investigate changes in attitudes toward older adults and the self-assessment of knowledge in dentistry among older adults before and after clinical practice in gerodontology from 2019 to 2021. The study used a questionnaire on required competencies, consisting of behavioral and achievement goals for older adults and the Japanese version of the Attitudes Towards the Elderly(ATE), which represents emotional attitudes toward older adults. The results demonstrate that students self-rated their abilities more positively after clinical practice and homebound dentistry practice than before(p<0.01). Attitudes toward older adults also changed more favorably(p=0.012). However, when comparing the amount of change in each survey item based on experience of home-based dentistry practice and the duration of interruption of clinical practice, no statistically significant differences were observed between the groups. This study showed changes in attitudes toward older adults and self-evaluation of required competencies through clinical practice. The evaluation of changes in attitudes toward older adults and self-evaluation of knowledge in gerodontology may help to confirm the effectiveness of training in gerodontology and to improve the content of future education.</p>

    DOI: 10.11259/jsg.39.3_162

    CiNii Research

  • Association between masticatory function, frailty, and functional disability: an observational study

    Furuhashi, H; Honda, T; Furuta, Y; Tomooka, S; Tajimi, T; Kimura, Y; Yoshida, D; Ninomiya, T

    BMC GERIATRICS   24 ( 1 )   538   2024.6   eISSN:1471-2318

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    Language:English   Publisher:BMC Geriatrics  

    Background: Increase in functional disability in aging societies is an international medical and public health issue. Masticatory function may be a potential risk factor for functional disability, but the role of frailty in the association has not been clarified. Methods: Forty thousand five hundred sixty-two community-dwelling older adults aged 65 years and over who were insured by public health insurance as of April 2018 were followed up for a median of 3.0 years. Masticatory function was categorized as good, moderate, or poor based on a self-reported questionnaire. The development of functional disability was defined as a new certification of the need for long-term care. A Cox proportional hazards model was used to calculate hazard ratios (HRs) and their 95% confidence intervals (CIs). Results: During the follow-up period, 1,397 individuals experienced functional disability. After adjusting for age, sex, comorbidities, medical history, and lifestyle behaviors, the HR for incident functional disability was significantly higher in the moderate and poor groups compared to the good group (moderate, HR 1.21 [95% CI, 1.07–1.37]; poor, HR 1.64 [95% CI, 1.03–2.62]). However, after additional adjustment for frailty-related factors—namely, underweight, regular exercise, and gait speed—the association was attenuated in both the moderate group (HR 1.06 [95% CI, 0.94–1.21]) and the poor group (HR 1.51 [95% CI, 0.94–2.41]). Conclusions: Masticatory dysfunction was significantly associated with incident functional disability in a community-dwelling older Japanese population. Our findings suggest that masticatory dysfunction may be a surrogate of frailty rather than a direct cause of functional disability.

    DOI: 10.1186/s12877-024-05131-w

    Web of Science

    Scopus

    PubMed

  • Serum Lipopolysaccharide-binding Protein Levels and the Incidence of Metabolic Syndrome in a General Japanese Population: the Hisayama Study

    Tomooka Shoko, Oishi Emi, Asada Masako, Sakata Satoko, Hata Jun, Chen Sanmei, Honda Takanori, Suzuki Kosuke, Watanabe Hiroshi, Murayama Norihito, Wada Naohisa, Kitazono Takanari, Ninomiya Toshiharu

    Journal of Epidemiology   34 ( 1 )   1 - 7   2024.1   ISSN:09175040 eISSN:13499092

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    Language:English   Publisher:Japan Epidemiological Association  

    <p><b>Background:</b> The association between chronic lipopolysaccharide exposure and the development of metabolic syndrome (MetS) is unclear. In this study we examined the association between serum lipopolysaccharide-binding protein (LBP) levels, an indicator of lipopolysaccharide exposure, and the development of MetS in a general Japanese population.</p><p><b>Methods:</b> 1,869 community-dwelling Japanese individuals aged ≥40 years without MetS at baseline examination in 2002–2003 were followed up by repeated examination in 2007–2008. MetS was defined according to the Japanese criteria. Serum LBP levels were classified into quartiles (quartiles 1–4: 2.20–9.56, 9.57–10.78, 10.79–12.18, and 12.19–24.34 µg/mL, respectively). Odds ratios (ORs) for developing MetS were calculated using a logistic regression model.</p><p><b>Results:</b> At the follow-up survey, 159 participants had developed MetS. Higher serum LBP levels were associated with greater risk of developing MetS after multivariable adjustment for age, sex, smoking, drinking, and exercise habits (OR [95% confidence interval] for quartiles 1–4: 1.00 [reference], 2.92 [1.59–5.37], 3.48 [1.91–6.35], and 3.86 [2.12–7.03], respectively; <i>P</i> for trend <0.001). After additional adjustment for homeostasis model assessment of insulin resistance, this association was attenuated but remained significant (<i>P</i> for trend = 0.007). On the other hand, no significant association was observed after additional adjustment for serum high-sensitivity C-reactive protein (<i>P</i> for trend = 0.07).</p><p><b>Conclusion:</b> In the general Japanese population, our findings suggest that higher serum LBP levels are associated with elevated risk of developing MetS. Low-grade endotoxemia could play a role in the development of MetS through systemic chronic inflammation and insulin resistance.</p>

    DOI: 10.2188/jea.je20220232

    Web of Science

    Scopus

    PubMed

    CiNii Research

  • Database profile of the Fukuoka-City Information Platform for Community-based Integrated Care. Invited Reviewed International journal

    Takanori Honda, Hiroko Furuhashi, Yoshihiko Furuta, Shoko Tomooka, Takahiro Tajimi, Fumi Nagasawa, Emi Oishi, Yasumi Kimura, Daigo Yoshida, Toshiharu Ninomiya.

    Annals of Clinical Epidemiology   2024.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.37737/ace.24002

  • Database profile of the Fukuoka-City Information Platform for Community-based Integrated Care

    Honda Takanori, Furuhashi Hiroko, Furuta Yoshihiko, Tomooka Shoko, Tajimi Takahiro, Nagasawa Fumi, Oishi Emi, Kimura Yasumi, Yoshida Daigo, Ninomiya Toshiharu

    Annals of Clinical Epidemiology   6 ( 1 )   5 - 11   2024   eISSN:24344338

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    Language:English   Publisher:Society for Clinical Epidemiology  

    <p><b>BACKGROUND</b></p><p>The Fukuoka-City Information Platform for Community-based Integrated Care is an advanced big data platform that aggregates information on the health and medical services of Fukuoka citizens. Fukuoka City is engaged in a joint project with Kyushu University to promote policy making through a large-scale real-world data analysis. This paper describes the framework for this cooperative effort and the features of the analytical platform.</p><p><b>METHODS</b></p><p>Fukuoka City is the fifth most populous ordinance-designated city in Japan, with an estimated population of approximately 1.6 million. Under an agreement with Fukuoka City, Kyushu University was granted access to a portion of the city’s anonymized healthcare database as secondary-use information. The database contains information on resident registration, health insurance claims, specific health checkups and health checkups for the older adults, specific health guidance, long-term care insurance data, and cancer screenings collected after fiscal year 2012. Each of these constituent datasets can be interlinked using anonymized hashed key variables, allowing individuals to be followed across databases and over time.</p><p><b>CONCLUSIONS</b></p><p>The platform allows longitudinal investigation of the complex association between various aspects of healthcare, such as medical procedures, examinations, interviews, medical costs, long-term care certifications, and care costs. The platform can provide valuable public-health information because it is relatively large for a single database, and because it allows analysis of data across multiple domains and tracing of individuals over time.</p>

    DOI: 10.37737/ace.24002

    PubMed

    CiNii Research

Presentations

  • Association between oral rehabilitation and function inesophageal cancer patients.

    Shoko Tomoka, Junichi Yamazoe, Michiko Furuta, Naohisa Wada, Haruhiko Kashiwazaki.

    2025 AADOCR/CADR Annual Meeting & Exhibition 

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    Event date: 2025.3

  • 当院における脳血管疾患患者に対する歯科摂食嚥下リハビリテーションチームの取り組み

    塚本葉子、友岡祥子、神野哲平、山添淳一   

    第38回日本口腔口腔リハビリテーション学会・学術大会 

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    Event date: 2024.12

  • 周術期食道癌患者における摂食嚥下リハビリテーションと口腔機能との関連

    友岡祥子、塚本葉子、井上昂也、合津佳祐

    第37回日本口腔診断学会 第34回日本口腔内科学会合同学術大会 

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    Event date: 2024.9

  • 当院における周術期食道癌患者に対する歯科摂食嚥下リハビリテーションチームの取り組み

    友岡祥子、 井上昂也 、山添淳一 、荻野洋一郎、神野哲平、塚本葉子、萱野綾華 、和田尚久、柏﨑晴彦

    第21回日本口腔ケア学会総会・学術大会  2024.4 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 歯科治療恐怖症の患者に対しMDASによる恐怖感の推移を評価した診療が有効であった症例

    友岡祥子、水谷慎介、柏﨑晴彦

    第33回日本有病者歯科医療学会学術大会  2024.3 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 血清LBP値のメタボリックシンドローム発症との関連:久山町研究

    友岡祥子、大石絵美、浅田雅子、秦淳、和田尚久、二宮利治

    第56回日本循環器病予防学会学術集会  2020.12 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 地域高齢者住民における歯数とサルコペニア発症との関連:久山町研究

    友岡祥子、坂田智子、大石絵美、本田貴紀、秦 淳、古田美智子、山下喜久、和田尚久、北園孝成、二宮利治

    第33回日本老年医学会九州地方会  2023.3 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 経口摂取困難であった高齢患者に対し多職種連携のチームによる診療が有効であった症例

    友岡 祥子、柏﨑晴彦

    第34回日本老年歯科医学会  2023.6 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 口腔粘膜に付着する液状乳化物の呈味増強効果についての検討

    山添 淳一, 川端 由子, 友岡 祥子, 田口 大夢, 朝武 宗明, 青柳 守紘, 柏崎 晴彦, 重村 憲徳

    日本摂食・嚥下リハビリテーション学会  2024.12  (一社)日本摂食嚥下リハビリテーション学会

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    Language:Japanese  

  • 周術期食道癌患者における摂食嚥下リハビリテーションと口腔機能との関連

    友岡 祥子, 塚本 葉子, 井上 昂也, 合津 佳祐

    日本口腔内科学会雑誌  2024.12  (一社)日本口腔内科学会

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    Language:Japanese  

  • 地域高齢住民における歯数とサルコペニア発症との関連 久山町研究

    友岡 祥子, 柏崎 晴彦, 二宮 利治

    日本老年歯科医学会  2024.6  (一社)日本老年歯科医学会

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    Language:Japanese  

  • 当院における周術期食道癌患者に対する歯科摂食嚥下リハビリテーションチームの取り組み

    友岡 祥子, 井上 昂也, 山添 淳一, 荻野 洋一郎, 神野 哲平, 塚本 葉子, 萱野 綾華, 和田 尚久, 柏崎 晴彦

    日本口腔ケア学会  2024.4  (一社)日本口腔ケア学会

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    Language:Japanese  

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Professional Memberships

  • The Japanese Society of Dentistry for Medically Compromised Patient

  • The Japanese Society of Dysphagia Rehabilitation

  • Japanese society of Gerodontology

Research Projects

  • 食道がん患者の社会復帰を支援するオーダーメイドリハビリテーションプランの開発

    Grant number:25K20704  2025.4 - 2028.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

    友岡 祥子

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    Grant type:Scientific research funding

  • 低濃度エンドトキシンと脂肪肝との関連:久山町研究

    Grant number:23K19864  2023 - 2024

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Research Activity start-up

    友岡 祥子

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    Authorship:Principal investigator  Grant type:Scientific research funding

    脂肪肝は肝臓におけるメタボリックシンドローム(MetS)の表現型と言われており、その予防には早期からの危険因子の管理が重要である。近年、腸内のグラム陰性細菌に由来するエンドトキシンが血中移行することで、低濃度の血中エンドトキシン(代謝性エンドトキシン血症)が炎症を惹起し、肥満の病態に関与することが注目されている。本研究では、血中エンドトキシンの安定マーカーであるリポ多糖結合蛋白質(Lipopolysaccharide-binding protein, LBP)の血中濃度を用いて、日本人の地域住民における血中エンドトキシン濃度(血清LBP値)と脂肪肝との関連を縦断的に検討する。

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Clinician qualification

  • Certifying physician

    日本老年歯科医学会

  • 認定士

    日本摂食嚥下リハビリテーション学会