KIM JEONGHYUN
バナー付きURL
Organization
Faculty of Engineering Department of Mechanical Engineering Associate Professor
School of Engineering
（Concurrent）
Graduate School of Engineering Department of Mechanical Engineering（Concurrent）
Title
Associate Professor
External link
Research Areas
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Life Science / Biomedical engineering
Degree
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Ph.D. （ 2017.9 The University of Tokyo ）
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修士（工学） （ 2014.9 The University of Tokyo ）
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Bachelor of Engineering （ 2009.11 The University of Sydney ）
Research History
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Kyushu University Graduate School of Engineering, Department of Mechanical Engineering, Division of Bioengineering Associate Professor
2025.4 - Present
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Nagoya University Graduate School of Engineering, Department of Mechanical Systems Engineering Assistant Professor
2021.4 - 2025.3
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Kyoto University Institute for Frontier Life and Medical Sciences Postdoctoral Fellow
2018.11 - 2021.3
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The University of Tokyo Graduate School of Engineering, Department of Bioengineering Research Fellow of the Japan Society for the Promotion of Science (PD)
2017.10 - 2018.10
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The University of Tokyo Graduate School of Engineering, Department of Mechanical Engineering Research Fellow of the Japan Society for the Promotion of Science (DC2)
2017.4 - 2017.9
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The State University of New York at Buffalo, USA Department of Physiology and Biophysics Science (Frederick Sachs Lab) Visiting scholar
2016.1 - 2016.3
Education
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The University of Tokyo 大学院工学系研究科機械工学専攻 博士課程
2014.10 - 2017.9
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The University of Tokyo 大学院工学系研究科機械工学専攻 修士課程
2012.10 - 2014.9
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The University of Sydney Faculty of Engineering Biomedical Engineering
2006.3 - 2009.11
Country：Australia
Awards
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第32回（2023年度）瀬口賞
2024.5 日本機械学会バイオエンジニアリング部門
キム・ジョンヒョン
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The Yamaguchi Medal
2019.11 Asian-Pacific Association for Biomechanics
Jeonghyun Kim
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日本機械学会東海支部 2024年度 研究賞
2025.3 日本機械学会東海支部
キム・ジョンヒョン
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日本生体医工学会東海支部 2023年度 研究奨励賞
2023.10 日本生体医工学会東海支部
キム・ジョンヒョン
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日本機械学会東海支部 2021年度 奨励賞
2022.3 日本機械学会東海支部
キム・ジョンヒョン
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2020 JBSE Graphics of the Year Award
2021.6 Journal of Biomechanical Science and Engineering
Kim J, Kigami H, Adachi T
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2020 JBSE Papers of the Year Award
2021.6 Journal of Biomechanical Science and Engineering
Kim J, Kigami H, Adachi T
Papers
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Application of hydrostatic pressure up-regulates Sost gene expression in osteocytic spheroid Reviewed
Jeonghyun Kim, Kotone Niioka, Eijiro Maeda, Takeo Matsumoto
Bioscience, Biotechnology, and Biochemistry 2025.2
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Macroscopic creep behavior of spheroids derived from mesenchymal stem cells under compression Reviewed
Takashi Inagaki, Jeonghyun Kim, Eijiro Maeda, Takeo Matsumoto
Journal of the Mechanical Behavior of Biomedical Materials 2025.1
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Spatiotemporal analysis of multi-scale cell structure in spheroid culture reveals hypertrophic chondrocyte differentiation Reviewed
Kosei Tomida, Jeonghyun Kim, Eijiro Maeda, Taiji Adachi, Takeo Matsumoto
Cell and Tissue Research 2024.9
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3D quantitative assessment for nuclear morphology in osteocytic spheroids with optical clearing technique Reviewed
Takashi Inagaki, Jeonghyun Kim, Kosei Tomida, Eijiro Maeda, Takeo Matsumoto
Integrative Biology 2023.4
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Spheroid culture for chondrocytes triggers the initial stage of endochondral ossification Reviewed
Jeonghyun Kim, Kosei Tomida, Takeo Matsumoto, Taiji Adachi
Biotechnology and Bioengineering 2022.11
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Effect of chemically induced osteogenesis supplements on multicellular behavior of osteocytic spheroids Reviewed
Jeonghyun Kim, Takashi Inagaki, Junko Sunaga, Taiji Adachi, Takeo Matsumoto
Biochemical and Biophysical Research Communications 2022.9
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Comparative gene expression analysis for pre-osteoblast MC3T3-E1 cells under non-adhesive culture toward osteocyte differentiation Reviewed
Jeonghyun Kim, Hiroyuki Kigami, Taiji Adachi
Journal of Bioscience and Bioengineering 2021.12
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Modulation of Sost expression by hypoxia in 3D scaffold-free osteocytic tissue Reviewed
Jeonghyun Kim, Taiji Adachi
Tissue Engineering Part A 2021.8
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Cell-fate decision of mesenchymal stem cells toward osteocyte differentiation is committed by spheroid culture Reviewed
Jeonghyun Kim, Taiji Adachi
Scientific Reports 2021.6
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Cell condensation triggers the differentiation of osteoblast precursor cells to osteocyte-like cells Reviewed
Jeonghyun Kim, Taiji Adachi
Frontiers in Bioengineering and Biotechnology 2019.10
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Quasi-static and dynamic mechanical properties of artificial tissue fabricated from concentrated collagen using mechano-chemical treatment Reviewed
Yoshikazu Ohashi, Takashi Suzuki, Tomohito Iwasaki, Keita Goto, Jeonghyun Kim, Takeo Matsumoto, Masaomi Saeki, Eijiro Maeda
Materials Today Communications 2025.4
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Biomechanical properties of regenerated digital flexor tendon in immature newt following complete transection Reviewed
Yu Masuda-Otsuka, Tomoka Kamiya, Daisuke Suzuki, Toshinori Hayashi, Tomohito Iwasaki, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda
Bio-medical Engineering and Materials 2025
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Functional analysis of regenerated digit in newt following complete amputation at proximal interphalangeal joint Reviewed
Takeshi Kasahara, Machiko Teramoto, Kiyokazu Agata, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda
Journal of Biomechanical Science and Engineering 2024.10
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Novel air-liquid interface culture model to investigate stiffness-dependent behaviors of alveoli epithelial cells Reviewed
Yuto Takahashi, Satoru Ito, Junfeng Wang, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda
Biochemical and Biophysical Research Communications 2024.5
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Biomechanical analysis of tendon regeneration capacity of Iberian ribbed newts following transection injury: Comparison to a mouse model Reviewed
Fumiya Sato, Yu Masuda, Daisuke Suzuki, Toshinori Hayashi, Tomohito Iwasaki, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda
Journal of Orthopaedic Research 2024.3
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Contributions of collagen and elastin to elastic behaviours of tendon fascicle Reviewed
Yusei Ishizaki, Junfeng Wang, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda
Acta Biomaterialia 2024.1
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Macroscopic and microscopic mechanical analysis on tissue regenerated in central transverse slit defect in mouse patellar tendon Reviewed
Eijiro Maeda, Reiya Yamamori, Jeonghyun Kim, Takeo Matsumoto
Transactions of the JSME (in Japanese) 2023.4
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Dependency of the deformation of cell nucleus on stretch direction of tissue: Possible mechanotransduction pathway to anisotropic response of aortic media to hypertension Reviewed
Yong Fan, Junfeng Wang, Jeonghyun Kim, Eijiro Maeda, Takeo Matsumoto
Journal of the Mechanical Behavior of Biomedical Materials 2022.9
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Internal radial perfusion bioreactor promotes decellularization and recellularization of rat uterine tissue Reviewed
Narintadeach Charoensombut, Kinyoshi Kawabata, Jeonghyun Kim, Minki Chang, Tsuyoshi Kimura, Akio Kishida, Takashi Ushida, Katsuko Furukawa
Journal of Bioscience and Bioengineering 2022.1
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Uniaxially-fixed mechanical boundary condition elicits cellular alignment in collagen matrix with induction of osteogenesis Reviewed
Jeonghyun Kim, Keiichi Ishikawa, Junko Sunaga, Taiji Adachi
Scientific Reports 2021.4
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Characterization of self-organized osteocytic spheroids using mouse osteoblast-like cells Reviewed
Jeonghyun Kim, Hiroyuki Kigami, Taiji Adachi
Journal of Biomechanical Science and Engineering 2020.6
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Acquired contractile ability in human endometrial stromal cells by passive loading of cyclic tensile stretch Reviewed
Jeonghyun Kim, Takashi Ushida, Kevin Montagne, Yasushi Hirota, Osamu Yoshino, Takehiro Hiraoka, Yutaka Osuga, Katsuko Furukawa
Scientific Reports 2020.6
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Fabrication of extracellular matrix hydrogel derived from uterine tissues Reviewed
Kinyoshi Kawabata, Narintadeach Charoensombut, Jeonghyun Kim, Tsuyoshi Kimura, Akio Kishida, Takashi Ushida, Katsuko Furukawa
Japanese Journal of Clinical Biomechanics 2020.5
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Fabrication of uterine decellularized matrix using high hydrostatic pressure through depolymerization of actin filaments Reviewed
Jeonghyun Kim, Shu Takeda, Narintadeach Charoensombut, Kinyoshi Kawabata, Yugo Kishimoto, Tsuyoshi Kimura, Akio Kishida, Takashi Ushida, Katsuko Furukawa
Journal of Biomechanical Science and Engineering 2019.9
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Hypergravity down-regulates c-fos gene expression via ROCK/Rho-GTP and the PI3K signaling pathway in murine ATDC5 chondroprogenitor cells Reviewed
Jeonghyun Kim, Kevin Montagne, Hidetoshi Nemoto, Takashi Ushida, Katsuko Furukawa
PLoS ONE 2017.9
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Involvement of the mTOR pathway in redifferentiation of bovine chondrocytes under dynamic hydrostatic loading Reviewed
Kevin Montagne, Dongig Oh, Jeonghyun Kim, Takashi Ushida, Katsuko S Furukawa
Japanese Journal of Clinical Biomechanics 2016
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Enhanced chondrogenesis with upregulation of PKR using a novel hydrostatic pressure bioreactor Reviewed
Jeonghyun Kim, Kevin Montagne, Takashi Ushida, Katsuko S Furukawa
Bioscience, Biotechnology, and Biochemistry 2015.2
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Mechanical and Histopathological Comparison between Commercialized and Newly Designed Coronary Bare Metal Stents in a Porcine Coronary Restenosis Model Reviewed
Kyung Seob Lim, In Ho Bae, Jung Ha Kim, Dae Sung Park, Jong Min Kim, Jeonghyun Kim, Doo Sun Sim, Young Joon Hong, Myung Ho Jeong
Chonnam Medical Journal 2013.4
Professional Memberships
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The Japanese Society of Biorheology
2022.4 - Present
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The Japanese Society for Medical and Biological Engineering
2021.4 - Present
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The Japanese Society for Regenerative Medicine
2015.4 - Present
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The Japan Society of Mechanical Engineers
2014.4 - Present
Committee Memberships
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日本機械学会 バイオエンジニアリング部門 渉外委員会 幹事
2025.4 - Present
Committee type：Academic society
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日本機械学会 バイオエンジニアリング部門 運営委員会 委員
2025.4 - Present
Committee type：Academic society
Research Projects
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骨オルガノイド樹立を目指した骨細胞分化メカニズムの解明
Grant number：23K17193 2023.4 - 2025.3
日本学術振興会 科学研究費助成事業 若手研究
Authorship：Principal investigator
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Scaffold-free tissue積層化による３次元骨軟骨モデル構築
Grant number：20K20181 2020.4 - 2023.3
日本学術振興会 科学研究費助成事業 若手研究
Authorship：Principal investigator
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骨形成再現に向けた旋回培養法による骨オルガノイド大量作製及び新たな活用法構築
Grant number：19K23604 2019.8 - 2021.3
日本学術振興会 科学研究費助成事業 研究活動スタート支援
Authorship：Principal investigator Grant type：Scientific research funding
Class subject
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機械工学実験第二
2025.10 - Present Second semester
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Heat transfer II
2025.6 - Present Summer quarter
Teaching Student Awards
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Best Presentation Award
Year and month of award：2025.3
Classification of award-winning students：Undergraduate student Name of award-winning student：大久保 栄亮
マウス骨芽細胞様細胞由来スフェロイドの力学負荷培養：溝付シリコーンゴム膜を用いた圧縮培養装置の構築
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ベストプレゼンテーション賞
Year and month of award：2023.3
Classification of award-winning students：Postgraduate student Name of award-winning student：富田 航世
スフェロイド培養法によるマウス軟骨前駆細胞の肥大化軟骨細胞分化誘導
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The Outstanding Student Poster Award
Year and month of award：2022.6
Classification of award-winning students：Postgraduate student Name of award-winning student：富田航世
マウス軟骨前駆細胞の３次元スフェロイド培養による肥大軟骨分化およびアポトーシス誘導
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優秀講演賞
Year and month of award：2022.3
Classification of award-winning students：Undergraduate student Name of award-winning student：水島 慎吾
静水圧刺激がマウス骨芽前駆細胞の細胞形状・増殖に与える影響
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優秀講演賞
Year and month of award：2022.3
Classification of award-winning students：Undergraduate student Name of award-winning student：稲垣 貴士
組織透明化手法による３次元骨細胞スフェロイド内部の細胞核形状評価