YAMAZAKI KYOTARO
Organization
Faculty of Medical Sciences Department of Stem Cell Biology and Medicine Assistant Professor
Title
Assistant Professor
External link
Papers
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Epigenetic landscape of synthetic human centromere core regions: CENP-A assembly and euchromatic modifications interdependently antagonize heterochromatin accumulation Reviewed
Ohzeki, J; Watanabe, A; Lee, JX; Minami, C; Kugou, K; Yamazaki, K; Shirasawa, K; Isobe, S; Endo, Y; Kazuki, Y
NUCLEIC ACIDS RESEARCH 54 ( 12 ) 2026.6
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High-throughput CRISPR live-cell imaging of low-frequency chromosomal events quantifies the latent efficiency of chromosome engineering
Hu, X; Iwamoto, Y; Yamazaki, K; Kishima, N; Otaki, N; Miyamoto, H; Miyaoka, Y; Kazuki, Y; Ota, S
BIORXIV 2026.5
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Generation of transchromosomic mice harboring HLA-A/B/C and human B2M via mouse artificial chromosome and triple BAC integration Reviewed
Kishima, N; Moriwaki, T; Uno, N; Suzuki, T; Abe, S; Sugawara, M; Nagashima, Y; Kazuki, K; Endo, T; Yamazaki, K; Nakagawa, W; Yuno, R; Moriguchi, Y; Matsukura, S; Tomizuka, K; Kazuki, Y
SCIENTIFIC REPORTS 15 ( 1 ) 2025.7
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Development of an OATP1-humanized transchromosomic mouse model for prediction of hepatic drug uptake in humans. Reviewed International journal
Koishikawa, T; Kazuki, K; Ohnishi, R; Okita, K; Mizuno, T; Abe, S; Nanchi, I; Masago, Y; Yamazaki, K; Ohzeki, JI; Kusuhara, H; Kazuki, Y
DRUG METABOLISM AND DISPOSITION: THE BIOLOGICAL FATE OF CHEMICALS 53 ( 2 ) 100028 - 100028 2025.2
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Microcell-mediated chromosome transfer between non-identical human iPSCs Reviewed
Uno, N; Miyamoto, H; Yamazaki, K; Egawa, M; Kobayashi, H; Kazuki, K; Osaki, M; Suzuki, T; Hamamichi, S; Oshimura, M; Tomizuka, K; Kazuki, Y
MOLECULAR THERAPY - NUCLEIC ACIDS 35 ( 4 ) 102382 - 102382 2024.12
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Generation of Monosomy 21q Human iPS Cells by CRISPR/Cas9‐Mediated Interstitial Megabase Deletion Reviewed
Egawa, M; Uno, N; Komazaki, R; Ohkame, Y; Yamazaki, K; Yoshimatsu, C; Ishizu, Y; Okano, Y; Miyamoto, H; Osaki, M; Suzuki, T; Hosomichi, K; Aizawa, Y; Kazuki, Y; Tomizuka, K
GENES TO CELLS 2024.11
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Rapid human genomic DNA cloning into mouse artificial chromosome via direct chromosome transfer from human iPSC and CRISPR/Cas9-mediated translocation. Reviewed International journal
Miyamoto, H; Kobayashi, H; Kishima, N; Yamazaki, K; Hamamichi, S; Uno, N; Abe, S; Hiramuki, Y; Kazuki, K; Tomizuka, K; Kazuki, Y
NUCLEIC ACIDS RESEARCH 2024.1
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Co-treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency Reviewed
Uno, N; Satofuka, H; Miyamoto, H; Honma, K; Suzuki, T; Yamazaki, K; Ito, R; Moriwaki, T; Hamamichi, S; Tomizuka, K; Oshimura, M; Kazuki, Y
MOLECULAR THERAPY - NUCLEIC ACIDS 2023.7
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Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate Reviewed
Satofuka, H; Wang, Y; Yamazaki, K; Hamamichi, S; Fukuhara, T; Rafique, A; Osako, N; Kanazawa, I; Endo, T; Miyake, N; Honma, K; Nagashima, Y; Hichiwa, G; Shimoya, K; Abe, S; Moriwaki, T; Murakami, Y; Gao, X; Kugoh, H; Oshimura, M; Ito, Y; Kazuki, Y
SCIENTIFIC REPORTS 13 ( 1 ) 2023.3
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Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery Reviewed International journal
Yamazaki, K; Matsuo, K; Okada, A; Uno, N; Suzuki, T; Abe, S; Hamamichi, S; Kishima, N; Togai, S; Tomizuka, K; Kazuki, Y
SCIENTIFIC REPORTS 12 ( 21790 ) 1 - 14 2022.12
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Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci Reviewed International journal
Satofuka, H; Abe, S; Moriwaki, T; Okada, A; Kazuki, K; Tanaka, H; Yamazaki, K; Hichiwa, G; Morimoto, K; Takayama, H; Nakayama, Y; Hatano, S; Yada, Y; Murakami, Y; Baba, Y; Oshimura, M; Tomizuka, K; Kazuki, Y
NATURE COMMUNICATIONS 13 ( 1 ) 1841 2022.4 （ eISSN:2041-1723 ）
Presentations
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Kishima Nanami, Miyamoto Hitomaru, Abe Satoshi, Okada Akane, Nakagawa Wakana, Yamazaki Kyotaro, Kazuki Kanako, Moriwaki Takashi, Uno Narumi, Tomizuka Kazuma, Kazuki Yasuhiro
Experimental Animals 2024 (公社)日本実験動物学会