Kyushu University Academic Staff Educational and Research Activities Database
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Nobuyuki SUDO Last modified date:2020.09.11

Professor / Internal Medicine, Graduate School of Medical Science
Department of Clinical Medicine
Faculty of Medical Sciences

Graduate School
Undergraduate School
Administration Post

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Department of Psychosomatic Medicine .
Academic Degree
Doctor of Medicine
Country of degree conferring institution (Overseas)
Field of Specialization
Psychosomatics, Stress, Allergy, psychoneuroimmunology
Total Priod of education and research career in the foreign country
Outline Activities
Our recent research targets the effects of environmental factor on neuro-immuno-endocrine interaction.
Research Interests
  • Stress causes bacterial trans location.
    keyword : stress, bacterial trans location
  • Clarification of Anorexia Nervosa patients condition by Microbiota gut-brain axis
    keyword : Anorexia Nervosa, Microbiota gut-brain axis
  • Talks with bacteria and the host through catecholamine:Creation of a new paradigm of the mind and body correlation
    keyword : Inter-kingdom signaling, catecholamine, stress
  • The whole aspect and elucidation of the mechanism of the host action change due to intestinal bacteria
    keyword : Intestinal bacteria, stress, metabolic loam
  • How does the stress bring about the fortunetelling infectiousness of the host?
    keyword : Inter-kingdom signaling, catecholamine, stress, infectious disease
  • Does enteral Flora influence the weight gain of the anorexic?
    keyword : Enteral Flora, adiposity, anorexia nervosa, eating disorder
  • Psychoneuoimmunology
    keyword : stress, nervous system, endocrine system, immune system, interaction
  • The Gut Microbiome
    Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral
    Performance in Female Mice.

    keyword : Microbiome
    2000.01Intestinal microbiota and HPA stress response.
Academic Activities
1. 須藤 信行, Microbiome, HPA axis and production of endocrine hormones in the gut. , 10.1007/978-1-4939-0897-4_8., 817:177-94. , 2014.07.
2. Sudo N, Role of microbiome in regulating the HPA axis and its relevance to allergy., Chem Immunol Allerg, 98, 163-75, 2012.06.
3. Hiramoto T, Chida Y, Sonoda J, Yoshihara K, Sudo N, Kubo C., The hepatic vagus nerve attenuates Fas-induced apoptosis in the mouse liver via alpha7 nicotinic acetylcholine receptor., Gastroenterology, 134(7):2122-31, 2008.06.
4. Chida Y, Sudo N, Sonoda J, Hiramoto T, Kubo C., Early-life psychological stress exacerbates adult mouse asthma via the hypothalamus-pituitary-adrenal axis., Am J Respir Crit Care Med., 75(4):316-22, 2007.02.
5. Chida Y, Sudo N, Takaki A, Kubo C., The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice., Gut, 10.1136/gut.2004.058818, 54, 7, 994-1002, 2005.07.
6. Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, Kubo C, Koga Y., Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system fo stress response in mice., Journal of Physiology (London), 10.1113/jphysiol.2004.063388, 558, 1, 263-275, 558, 263-275, 2004.07.
7. Chida Y, Sudo N, Sonoda J, Sogawa H, Kubo C., Electric foot-shock stress-induced excerbation of alpha-galactosylceramide-triggered apoptosis in the mouse liver., Hepatology, 10.1002/hep.20158, 39, 4, 1131-1140, 39, 1131-1140, 2004.03.
8. Hirayama K, Sudo N, Sueyasu M, Sonoda J, Chida Y, Oishi R, Kubo C, Endogenous glucocorticoids inhibit scratching behavior induced by the administration of compound 48/80 in mice, European Journal of Pharmacology, 10.1016/j.ejphar.2003.09.003, 481, 1, 59-65, 481 (1): 59-65, 2003.11.
9. Sudo N, Yu XN, Aiba Y, Oyama N, Sonoda J, Koga Y, Kubo C, An oral introduction of intestinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice, Clinical and Experimental Allergy, 10.1046/j.1365-2222.2002.01430.x, 32, 7, 1112-1116, 32 (7): 1112-1116, 2002.07.
10. Sudo N, Oyama N, Yu XN, Kubo C, Restraint stress-induced elevation of endogenous glucocorticoids decreases Peyer's patch cell numbers via mechanisms that are either dependent or independent on apoptotic cell death, Neuroimmunomodulation, 10.1159/000059391, 9, 6, 333-339, 9 (6): 333-339, 2001.12.
11. Sudo N, Sawamura SA, Tanaka K, Aiba Y, Kubo C, Koga Y, The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction, Journal of Immunology, 159, 4, 1739-1745, 159 (4): 1739-1745, 1997.08.
Membership in Academic Society
  • ACPM
  • American Psychosomatic Society
  • International College of Psychosomatic Medicine
Educational Activities
Psychosomatic view of psycho-neuro-immunology (Undergraduate)
Professional and Outreach Activities
Lecturer in Introduction to Psychosomatic Medicine (once a year).