Kyushu University Academic Staff Educational and Research Activities Database
Researcher information (To researchers) Need Help? How to update
Nobuyuki Sudo Last modified date:2021.11.26

Professor / Internal Medicine, Graduate School of Medical Science
Department of Clinical Medicine
Faculty of Medical Sciences

Graduate School
Undergraduate School
Administration Post

E-Mail *Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
 Reseacher Profiling Tool Kyushu University Pure
Department of Psychosomatic Medicine .
Academic Degree
Doctor of Medicine
Country of degree conferring institution (Overseas)
Field of Specialization
Psychosomatics, Stress, Allergy, psychoneuroimmunology
Total Priod of education and research career in the foreign country
Outline Activities
Our recent research targets the effects of environmental factor on neuro-immuno-endocrine interaction.
Research Interests
  • Stress causes bacterial trans location.
    keyword : stress, bacterial trans location
  • Clarification of Anorexia Nervosa patients condition by Microbiota gut-brain axis
    keyword : Anorexia Nervosa, Microbiota gut-brain axis
  • Talks with bacteria and the host through catecholamine:Creation of a new paradigm of the mind and body correlation
    keyword : Inter-kingdom signaling, catecholamine, stress
  • The whole aspect and elucidation of the mechanism of the host action change due to intestinal bacteria
    keyword : Intestinal bacteria, stress, metabolic loam
  • How does the stress bring about the fortunetelling infectiousness of the host?
    keyword : Inter-kingdom signaling, catecholamine, stress, infectious disease
  • Does enteral Flora influence the weight gain of the anorexic?
    keyword : Enteral Flora, adiposity, anorexia nervosa, eating disorder
  • Psychoneuoimmunology
    keyword : stress, nervous system, endocrine system, immune system, interaction
  • The Gut Microbiome
    Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral
    Performance in Female Mice.

    keyword : Microbiome
    2000.01Intestinal microbiota and HPA stress response.
Academic Activities
1. Tomokazu Hata,Noriyuki Miyata,Shu Takakura, Kazuhfumi Yoshihara,Yasunari Asano, Tae Kimura-Todani, Makoto Yamashita, Xue Ting Zhang, Natsuru Watanabe, Katsunaka Mikami, Yasuhiro Koga,Nobuyuki Sudo., The Gut Microbiome Derived from Anorexia Nervosa Patients Impairs Weight Gain and Behavioral Performance in Female Mice, Endocrinology, 10.1210/en.2019-00408, 160, 10, 2441-2452, 2019.08.
2. Michelle G. Rooks, Patrick Veiga, Analise Z. Reeve, Sydney Lavoie, Koji Yasuda, Yasunari Asano, Kazufumi Yoshihara, Monia Michaud, Leslie Wardwell-Scott, Carey Ann Gallini, Jonathan N. Glickman, Nobuyuki Sudo, Curtis Huttenhower, Cammie F. Lesser, Wendy S. Garretta, QseC inhibition as an antivirulence approach for colitis-associated bacteria, Proceedings of the National Academy of Sciences of the United States of America, 10.1073/pnas.1612836114, 114, 1, 142-147, 2017.01.
3. Chihiro Morita, Hirokazu Tsuji, Tomokazu Hata, Motoharu Gondo, Shu Takakura, Keisuke Kawai, Kazufumi Yoshihara, Kiyohito Ogata, Koji Nomoto, Kouji Miyazaki, Nobuyuki Sudo, Gut Dysbiosis in Patients with Anorexia Nervosa, PloS one, 10.1371/journal.pone.0145274, 10, 12, e0145274, 2015.12.
4. Ryo Nishino, Katsunaka Mikami, H.ideki Takahashi, Shiniciro Tomonaga, Furuse, Tetsuya Hiramoto, Y. Aiba, Yasuhiro Koga, Nobuyuki Sudo, Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods, Neurogastroenterology and Motility, 10.1111/nmo.12110, 25, 6, 521-e371, 2013.06.
5. Yasunari Asano, Tetsuya Hiramoto, Ryo Nishino, Yuji Aiba, Tae Kimura, Kazufumi Yoshihara, Yasuhiro Koga, Nobuyuki Sudo, Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice, American Journal of Physiology - Gastrointestinal and Liver Physiology, 10.1152/ajpgi.00341.2012, 303, 11, G1288-G1295, 2012.12.
6. Forsythe P, Sudo N, Dinan T, Taylor VH, Bienenstock J, Mood and gut feelings, Brain Behav Immun., 24, 1, 9-16, 2010.01.
7. Tetsuya Hiramoto, Youichi Chida, Jyunko Sonoda, Kazufumi Yoshihara,Nobuyuki Sudo,Chiharu Kubo., The hepatic vagus nerve attenuates Fas-induced apoptosis in the mouse liver via alpha7 nicotinic acetylcholine receptor., Gastroenterology, 10.1053/j.gastro.2008.03.005, 134, 7, 2122-31, 134(7):2122-31, 2008.06.
8. Chida Y, Sudo N, Sonoda J, Hiramoto T, Kubo C., Early-life psychological stress exacerbates adult mouse asthma via the hypothalamus-pituitary-adrenal axis., Am J Respir Crit Care Med., 75(4):316-22, 2007.02.
9. Chida Y, Sudo N, Takaki A, Kubo C., The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice., Gut, 10.1136/gut.2004.058818, 54, 7, 994-1002, 2005.07.
10. Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, Kubo C, Koga Y., Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system fo stress response in mice., Journal of Physiology (London), 10.1113/jphysiol.2004.063388, 558, 1, 263-275, 558, 263-275, 2004.07.
11. Chida Y, Sudo N, Sonoda J, Sogawa H, Kubo C., Electric foot-shock stress-induced excerbation of alpha-galactosylceramide-triggered apoptosis in the mouse liver., Hepatology, 10.1002/hep.20158, 39, 4, 1131-1140, 39, 1131-1140, 2004.03.
12. Sudo N, Sawamura SA, Tanaka K, Aiba Y, Kubo C, Koga Y, The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction, Journal of Immunology, 159, 4, 1739-1745, 159 (4): 1739-1745, 1997.08.
13. Nobuyuki Sudo, Sada Aki Sawamura, Kazuo Tanaka, Yuhji Aiba, Chiharu Kubo, Yasuhiro Koga, The Requirement of Intestinal Bacterial Flora for the Development of an IgE Production System Fully Susceptible to Oral Tolerance Induction, Journal of Immunology, 159, 4, 1739-1745, 1997.08.
1. 須藤 信行, Possible contribution of gut dysbiosis to the pathology of anorexia nervosa, The 8th Beneficial Microbes conference, 2021.03.
2. 須藤 信行, Gut microbes influence the brain: how it was discovered and where it’s going (Plenary lecture)., The 26th Annual Meeting of Chinese Society of Psychosomatic Medicine & International Psychosomatic Medicine Forum, 2020.10.
Membership in Academic Society
  • International College of Psychosomatic Medicine
  • American Psychosomatic Society
  • ACPM
  • Japanese Society of Neurogastroenterology
  • The Japanese Association of Stress Science
  • Japanese Society for Parenteral and Enteral Nutrition
  • Japanese Society of Fatigue Science
  • The Japanese Society for the Study of Chronic Pain : JSSCP
  • Japanese Society of Transactional Analysis
  • Japanese Society of Autogenic Therapy
  • Japanese Society of Behavioral Medicine(JSBM)
Educational Activities
Psychosomatic view of psycho-neuro-immunology (Undergraduate)
Professional and Outreach Activities
Lecturer in Introduction to Psychosomatic Medicine (once a year).