Kyushu University Academic Staff Educational and Research Activities Database
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Nobuyuki Sudo Last modified date:2023.06.28

Professor / Internal Medicine, Graduate School of Medical Science
Department of Clinical Medicine
Faculty of Medical Sciences

Graduate School
Undergraduate School
Administration Post

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 Reseacher Profiling Tool Kyushu University Pure
Department of Psychosomatic Medicine .
Academic Degree
Doctor of Medicine
Country of degree conferring institution (Overseas)
Field of Specialization
Psychosomatics, Stress, Allergy, psychoneuroimmunology
Total Priod of education and research career in the foreign country
Outline Activities
Our recent research targets the effects of environmental factor on neuro-immuno-endocrine interaction.
Research Interests
  • Stress causes bacterial trans location.
    keyword : stress, bacterial trans location
  • Clarification of Anorexia Nervosa patients condition by Microbiota gut-brain axis
    keyword : Anorexia Nervosa, Microbiota gut-brain axis
  • Talks with bacteria and the host through catecholamine:Creation of a new paradigm of the mind and body correlation
    keyword : Inter-kingdom signaling, catecholamine, stress
  • The whole aspect and elucidation of the mechanism of the host action change due to intestinal bacteria
    keyword : Intestinal bacteria, stress, metabolic loam
  • How does the stress bring about the fortunetelling infectiousness of the host?
    keyword : Inter-kingdom signaling, catecholamine, stress, infectious disease
  • Does enteral Flora influence the weight gain of the anorexic?
    keyword : Enteral Flora, adiposity, anorexia nervosa, eating disorder
  • Psychoneuoimmunology
    keyword : stress, nervous system, endocrine system, immune system, interaction
  • The Gut Microbiome
    Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral
    Performance in Female Mice.

    keyword : Microbiome
    2000.01Intestinal microbiota and HPA stress response.
Academic Activities
1. Hata T,Miyata N,Takakura S, Yoshihara K,Asano Y, Kimura-Todani T, Yamashita M, Xue Ting Zhang, Watanabe N, Mikami K, Koga Y,Sudo N., The Gut Microbiome Derived from Anorexia Nervosa Patients Impairs Weight Gain and Behavioral Performance in Female Mice, Endocrinology, 10.1210/en.2019-00408, 160, 10, 2441-2452, 2019.08.
2. Michelle G. Rooks, Patrick Veiga, Analise Z. Reeve, Sydney Lavoie, Yasuda K, Asano Y, Yoshihara K, Michaud M, Leslie Wardwell-Scott, Carey Ann Gallini, Jonathan N. Glickman, Sudo N, Curtis Huttenhower, Cammie F. Lesser, Wendy S. Garretta, QseC inhibition as an antivirulence approach for colitis-associated bacteria, Proceedings of the National Academy of Sciences of the United States of America, 10.1073/pnas.1612836114, 114, 1, 142-147, 2017.01.
3. Morita C, Tsuji H, Hata T, Gondo M, Takakura S, Kawa Ki,Yoshihara K, Ogata K, Nomoto K, Miyazaki K, Sudo N., Gut Dysbiosis in Patients with Anorexia Nervosa, PloS one, 10.1371/journal.pone.0145274, 10, 12, e0145274, 2015.12.
4. Nishino R, Mikami K, Takahashi H, Tomonaga S, Hiramoto T, Aiba Y, Koga Y, Sudo N., Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods, Neurogastroenterology and Motility, 10.1111/nmo.12110, 25, 6, 521-e371, 2013.06.
5. Asano Y,Hiramoto T, Nishino R, Aiba Y, Kimura T, Yoshihara K, Koga Y, Sudo N., Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice, American Journal of Physiology - Gastrointestinal and Liver Physiology, 10.1152/ajpgi.00341.2012, 303, 11, G1288-G1295, 2012.12.
6. Forsythe P, Sudo N, Dinan T, Taylor VH, Bienenstock J, Mood and gut feelings, Brain Behav Immun., 24, 1, 9-16, 2010.01.
7. Hiramoto T, Chida Y, Sonoda J, Yoshihara K,Sudo K,Kubo C., The hepatic vagus nerve attenuates Fas-induced apoptosis in the mouse liver via alpha7 nicotinic acetylcholine receptor., Gastroenterology, 10.1053/j.gastro.2008.03.005, 134, 7, 2122-31, 134(7):2122-31, 2008.06.
8. Chida Y, Sudo N, Sonoda J, Hiramoto T, Kubo C., Early-life psychological stress exacerbates adult mouse asthma via the hypothalamus-pituitary-adrenal axis., Am J Respir Crit Care Med., 75(4):316-22, 2007.02.
9. Chida Y, Sudo N, Takaki A, Kubo C., The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice., Gut, 10.1136/gut.2004.058818, 54, 7, 994-1002, 2005.07.
10. Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, Kubo C, Koga Y., Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system fo stress response in mice., Journal of Physiology (London), 10.1113/jphysiol.2004.063388, 558, 1, 263-275, 558, 263-275, 2004.07.
11. Chida Y, Sudo N, Sonoda J, Sogawa H, Kubo C., Electric foot-shock stress-induced excerbation of alpha-galactosylceramide-triggered apoptosis in the mouse liver., Hepatology, 10.1002/hep.20158, 39, 4, 1131-1140, 39, 1131-1140, 2004.03.
12. Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y., The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction, Journal of Immunology, 159, 4, 1739-1745, 159 (4): 1739-1745, 1997.08.
1. 須藤 信行, Possible contribution of gut dysbiosis to the pathology of anorexia nervosa, The 8th Beneficial Microbes conference, 2021.03.
2. 須藤 信行, Gut microbes influence the brain: how it was discovered and where it’s going (Plenary lecture)., The 26th Annual Meeting of Chinese Society of Psychosomatic Medicine & International Psychosomatic Medicine Forum, 2020.10.
Membership in Academic Society
  • International College of Psychosomatic Medicine
  • American Psychosomatic Society
  • The Japanese Association of Stress Science
  • Japanese Society of Neurogastroenterology
  • Japanese Society of Fatigue Science
  • ACPM
Educational Activities
Psychosomatic view of psycho-neuro-immunology (Undergraduate)
Professional and Outreach Activities
Lecturer in Introduction to Psychosomatic Medicine (once a year).