Kyushu University Academic Staff Educational and Research Activities Database
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Tomohiko Akahoshi Last modified date:2024.01.25

Professor / Department of Emergency medicine, Advanced medicine and disaster medicine
Department of Clinical Medicine
Faculty of Medical Sciences

Graduate School
Undergraduate School
Other Organization
Administration Post

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Academic Degree
Doctor of phylosophy
Country of degree conferring institution (Overseas)
Field of Specialization
Emergency medicine, intensive care medicine, Portal hypertension, abdominal emergency medicine
ORCID(Open Researcher and Contributor ID)
Total Priod of education and research career in the foreign country
Outline Activities
Degrees/ Diplomas/ Licensures and Certifications
2002 Ph.D. Kyushu University, Graduate School
1995 M.D. Kyushu University

Present Academic Appointment
Associate Professor (Chief of section)
Graduate School of Medical Sciences,
Disaster and Emergency medicine,
Kyushu University, Fukuoka, Japan
2014~now Vice President Emergency and Critical care center,
Kyushu university hospital

Japanese Surgical Society
Japanese Association for Acute Medicine
The Japanese Society of Gastroenterological Surgery
Japanese Society of endoscopic surgery
Japanese Society of portal hypertension
Japan Society of Hepatology
Japanese trauma operative management course instructor

Board Certified SurgeonBoard Certified Gastroenterological Surgeon
Board Certified Emergency and critical care medicine
Board Certified Hepatologist of Japan Society of Hepatology
Board Certified Digestive endoscopy
Board Certified American Trauma Operative Management course
Research Interests
  • development for new treatment for ARDS
    keyword : ARDS
  • The efficacy of Adipose tissue derived stem cell on liver failure or liver cirrhosis
    keyword : liver failure
  • The effective training for acute care surgery
    keyword : acute care surgery
  • Portal hypertension
    Abnormal microcirculation in cirrhotic liver
    keyword : Liver cirrhosis, Portal hypertension, splenomegaly
Current and Past Project
  • Adipose derived mesenchymal stem cells (ADSC) have an ability to diffrentiate a variety of cell such as muscle, hepatocyte and so on. Therefore, these cell is expected as a new therapy for organ failure in the patiets. Recently, not only the ability of differentiation but also paracrine effect of the stem cells is noted and increasingly reported. Our research progect found that ADSC product VEGF, HGF and TGF, which are important cytocine for tissue healing. We are working now for future application of human treatment.
Academic Activities
1. Akahoshi T. Hashizume M, Electromagnetic thermoablation to treat thrombocytopenia in cirrhotic and hypersplenic rats. J Gastroenterol Hepatol, 2011.07.
1. Akahoshi T, Sarcopenia is a predictive factor for prolonged intensive care unit stays in high-energy blunt trauma patients, Acute Medicine & Surgery, 2016.08.
2. Kinjo N, Kawanaka H, Akahoshi T, Maehara Y, Hepatic vein waveform and splenomegaly predict improvement of prothrombin time after splenectomy in hepatitis C virus-related cirrhotic patients., Hepatol Res, 10.1111/hepr.12040, 43, 9, 933-941, 2013.09.
3. Sumida K, Shimoda S, Iwasaka S, Hisamoto S, Kawanaka H, AKahoshi T, Ikegami T, Akashi K, Characteristics of splenic CD8+ T cell exhaustion in patients with hepatitis C, Clin Exp Immunol, 10.1111/cei., 174, 1, 172-178, 2013.08.
4. Akahoshi T, Merits of prophylactic sclerotherapy for esophageal varices concomitant unresectable hepatocellular carcinoma: Prospective randomized study., Dig Endosc., 10.1111/den.12119, 2013.05.
5. Tsutsumi N, Tomikawa M, Uemura M, Akahoshi T, Image-guided laparoscopic surgery in an open MRI operating theater., Surg Endosc. , 1007/s00464-012-2737, 27, 6, 2178-2184, 2013.01.
6. AKAHOSHI T, Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism, Surg Endosc., 24, 680-685, 2010.08.
7. Akahoshi T, Higashi H, Takeuchi H, Muto Y., Neuroendocrine carcinoma in liver , a case report and literature review. Surgery Today Surg Today., Surg Today., 2010;40(2):185-9., 2010.01.
8. Tomohiko Akahoshi, Selective cyclooxygenase(COX)inhibition causes damage to portal hypertensive gastric mucosa Role of nitric oxide and NF-kapperB, The FASEB Journal, 19, 9, 1163-1165, 2005.07.
9. Tomohiko Akahoshi, Role of the spleen in liver fibrosis in rats may be mediated by transforming growth factor beta-1., Journal of Gastroenterlogy and Hepatology, 10.1046/j.1440-1746.2002.02667.x, 17, 1, 59-65, 17(1): 59-65, 2002.01.
10. Akahoshi T, Long-term results of endoscopic Histoacryl injection sclerotherapy for gastric variceal bleeding: a 10-year experience., Surgery, 10.1067/msy.2002.119501, 131, 1, S176-S181, 131(1): 176-181, 2002.01.
Membership in Academic Society
  • Japanese Association for Acute Medicine
  • Japanese Association for sugery