Kyushu University Academic Staff Educational and Research Activities Database
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Tomohiko Akahoshi Last modified date:2022.11.07

Associate Professor / Disaster and Emergency medicine
Department of Advanced Medical Initiatives
Faculty of Medical Sciences

Graduate School
Undergraduate School
Other Organization
Administration Post

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 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Doctor of phylosophy
Country of degree conferring institution (Overseas)
Field of Specialization
Emergency medicine, intensive care medicine, Portal hypertension, abdominal emergency medicine
ORCID(Open Researcher and Contributor ID)
Total Priod of education and research career in the foreign country
Outline Activities
Degrees/ Diplomas/ Licensures and Certifications
2002 Ph.D. Kyushu University, Graduate School
1995 M.D. Kyushu University

Present Academic Appointment
Associate Professor (Chief of section)
Graduate School of Medical Sciences,
Disaster and Emergency medicine,
Kyushu University, Fukuoka, Japan
2014~now Vice President Emergency and Critical care center,
Kyushu university hospital

Japanese Surgical Society
Japanese Association for Acute Medicine
The Japanese Society of Gastroenterological Surgery
Japanese Society of endoscopic surgery
Japanese Society of portal hypertension
Japan Society of Hepatology
Japanese trauma operative management course instructor

Board Certified SurgeonBoard Certified Gastroenterological Surgeon
Board Certified Emergency and critical care medicine
Board Certified Hepatologist of Japan Society of Hepatology
Board Certified Digestive endoscopy
Board Certified American Trauma Operative Management course
Research Interests
  • development for new treatment for ARDS
    keyword : ARDS
  • The efficacy of Adipose tissue derived stem cell on liver failure or liver cirrhosis
    keyword : liver failure
  • The effective training for acute care surgery
    keyword : acute care surgery
  • Portal hypertension
    Abnormal microcirculation in cirrhotic liver
    keyword : Liver cirrhosis, Portal hypertension, splenomegaly
Current and Past Project
  • Adipose derived mesenchymal stem cells (ADSC) have an ability to diffrentiate a variety of cell such as muscle, hepatocyte and so on. Therefore, these cell is expected as a new therapy for organ failure in the patiets. Recently, not only the ability of differentiation but also paracrine effect of the stem cells is noted and increasingly reported. Our research progect found that ADSC product VEGF, HGF and TGF, which are important cytocine for tissue healing. We are working now for future application of human treatment.
Academic Activities
1. Laparoscopic splenectomy.
2. Akahoshi T. Hashizume M, Electromagnetic thermoablation to treat thrombocytopenia in cirrhotic and hypersplenic rats.
J Gastroenterol Hepatol
, J Gastroenterol Hepatol. , 2011.07.
1. Akahoshi T, Sarcopenia is a predictive factor for prolonged intensive care unit stays in high-energy blunt trauma patients, Acute Medicine & Surgery, 2016.08.
2. Kinjo N, Kawanaka H, Akahoshi T, Maehara Y, Hepatic vein waveform and splenomegaly predict improvement of prothrombin time after splenectomy in hepatitis C virus-related cirrhotic patients., Hepatol Res, doi: 10.1111/hepr.12040, 43, 9, 933-941, 2013.09.
3. Sumida K, Shimoda S, Iwasaka S, Hisamoto S, Kawanaka H, AKahoshi T, Ikegami T, Akashi K, Characteristics of splenic CD8+ T cell exhaustion in patients with hepatitis C, Clin Exp Immunol , doi: 10.1111/cei., 174, 1, 172-178, 2013.08.
4. Akahoshi T, Merits of prophylactic sclerotherapy for esophageal varices concomitant unresectable hepatocellular carcinoma: Prospective randomized study., Dig Endosc. , doi: 10.1111/den.12119, 2013.05.
5. Tsutsumi N, Tomikawa M, Uemura M, Akahoshi T, Image-guided laparoscopic surgery in an open MRI operating theater., Surg Endosc. , 1007/s00464-012-2737, 27, 6, 2178-2184, 2013.01.
6. Akahoshi T, Tomikawa M, Korenaga D, Ikejiri K, Saku M, Takenaka K. Maehara Y, Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism., Surg Endosc. 2010 Aug 19, 2010.08.
7. Akahoshi T, Higashi H, Takeuchi H, Muto Y., Neuroendocrine carcinoma in liver , a case report and literature review. Surgery Today
Surg Today.
, Surg Today., 2010;40(2):185-9., 2010.01.
8. Tomohiko Akahoshi, Selective cyclooxygenase(COX)inhibition causes damage to portal hypertensive gastric mucosa
Role of nitric oxide and NF-kapperB, The FASEB Journal, 19, 9, 1163-1165, 2005.07.
9. Tomohiko Akahoshi, Role of the spleen in liver fibrosis in rats may be mediated by transforming growth factor beta-1., Journal of Gastroenterlogy and Hepatology, 10.1046/j.1440-1746.2002.02667.x, 17, 1, 59-65, 17(1): 59-65, 2002.01.
10. Akahoshi T, Long-term results of endoscopic Histoacryl injection sclerotherapy for gastric variceal bleeding: a 10-year experience., Surgery, 10.1067/msy.2002.119501, 131, 1, S176-S181, 131(1): 176-181, 2002.01.
1. Utility of real time navigation system by open MRI for laparoscopic surgery.
2. The significance of surgery for gastrointestinal variceal bleeding..
3. The strategy for esophageal varices in the patients with VP3,4 HCC.
4. Complication of laparoscopic splenectomy in cirrhotic patients.
5. Emergency system for esophagogastric variceal bleeding in kyushu university .
  • The role of splenic immunosystem on liver fibrosis.