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Yoshinori Sawae Last modified date:2021.07.14

Professor / Machine Elements and Design Engineering Laboratory
Department of Mechanical Engineering
Faculty of Engineering


Graduate School
Undergraduate School
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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/yoshinori-sawae
 Reseacher Profiling Tool Kyushu University Pure
http://tribo1.mech.kyushu-u.ac.jp/TR/members2010-j.html
Phone
092-802-3073
Fax
092-802-3073
Academic Degree
Dr. Eng
Country of degree conferring institution (Overseas)
No
Field of Specialization
Bioengineering, Tribology
Total Priod of education and research career in the foreign country
01years00months
Research
Research Interests
  • Biomechanics of Dental Implant
    keyword : Dental Implant, Mechanics, Mechanical Stress, Strain, Bone
    2003.04Biomechanics of dental implant.
  • Wear of polymers in gaseous hydrogen
    keyword : Wear, Friction, Hydrogen, Polymer, PTFE, Fuel Cell System
    2006.07Polymer wear in hydrogen environment.
  • Development of lubricating function in articular cartilage under mechanical stimulations
    keyword : Articular Cartilage, Chondrocyte, Lubrication, Friction, Mechanotransduction
    2002.03.
  • Study on in vivo wear mechanics of UHMWPE used in joint prostheses and development of optimum wear test method for prosthetic joint materials
    keyword : Ultra-High Molecular Weight Polyethylene, Wear, Protein, Lipid
    2000.01In vivo wear mechanics and laboratory wear test method of UHMWPE.
Current and Past Project
  • Design of micro-bubble bioreactor system for tissue engineering
  • Research Center for Hydrogen Use and Strage, National Institute of Advanced Industrial Science and Technology
Academic Activities
Books
1. Yoshinori Sawae, Handbook of Polymer Tribology, World Scientific, 89-121, 2018.04.
2. Elucidation and Control of Tribology by Numerical Simulation and Surface Analysis.
3. C. Cho, T. Murakami, Y. Sawae, Wear of orthopaedic implants and artificial joints, Woodhead Publishing Limited, pp.221-245, 2012.05.
4. Yoshinori SAWAE, Effects of Physiological Factors on Wear of UHMWPE for Joint Prosthesis, Imperial College Press, Chapter 6 in Polymer Tribology, pp195-226, 2009.06.
Reports
1. Biotribology in Resin Material for Artificial Joint.
2. Friction and Wear of Polymers in Hydrogen Environment.
3. Effect of Traction Loading on Cartilaginous Tissue Formation by Chondrocyte.
4. Tribology on Prosthetic Polymer Materials.
5. Tribology of polymer sealing materials in hydrogen.
6. Introduction of Biotribology.
7. Tribology in Gaseous Hydrogen.
8. Tribology in High Pressure Hydrogen Gas.
Papers
1. Yoshinori Sawae , Takehiro Morita , Kyota Takeda , Shugo Onitsuka , Jyo Kaneuti , Tetsuo Yamaguchi, Joich Sugimura, Friction and wear of PTFE composites with different filler in high purity hydrogen gas, TRIBOLOGY INTERNATIONAL, 10.1016/j.triboint.2021.106884, 157, 106884, 2021.05, Single-filler polytetrafluoroethylene (PTFE) composites with different filler materials are prepared and their tribological characteristics are evaluated in gaseous hydrogen to investigate the tribological function of each filler material. The results indicated that glass fibre caused severe abrasion on the cast iron sliding counterface and hence increased wear in both the composite and counterface in hydrogen. The friction and wear characteristics of polyphenylene sulphide-filled PTFE in hydrogen are similar to those in ambient air because it formed a PTFE-based transfer film on the counterface regardless of the surrounding atmosphere. On the other hand, carbon fibre-filled PTFE indicates excellent low friction and low wear in hydrogen. In this case, both the composite surface and sliding counterface are covered with carbon-rich tribofilms..
2. Hironori Shinmori, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Effects of Synovial Fluid Constituents on Friction between UHMWPE and CoCrMo, Tribology Online, https://doi.org/10.2474/trol.15.283, 15, 4, 283-292, 2020.09, In this study, the reciprocating pin-on-plate sliding test was conducted between ultra-high molecular weight polyethylene (UHMWPE) and CoCrMo alloy with test lubricants containing representative synovial fluid constituents, such as proteins, hyaluronic acid, and phospholipids, to understand their effects on the in vivo friction and wear characteristics of implanted joint prostheses. To explore some details of the friction and wear process, the wear track remaining on the UHMWPE plate specimens was morphologically analyzed by laser microscopy and chemically analyzed by Fourier transform infrared (FTIR) spectroscopy. The influence of each constituent on the rheological properties of the test lubricant was also evaluated using a rotational rheometer. We observed that proteins had a definitive impact on the friction and wear process; proteins adsorbed on the UHMWPE surface and increased friction and wear by changing the predominant friction and wear mechanism from abrasive to adhesive. Phospholipids also increased friction while hyaluronic acid decreased friction by increasing the viscosity of the lubricants and enhancing the fluid dynamic effect. However, when phospholipids and hyaluronic acid were mixed with proteins, they enhanced the entrainment of the protein molecules into the contact area and increased the wear of UHMWPE..
3. Mechanical design assessment of zirconia abutment supported on titanium base.
4. D. Nečas, Yoshinori Sawae, T. Fujisawa, Kazuhiro Nakashima, Takehiro Morita, Tetsuo Yamaguchi, M. Vrbka, I. Křupka, M. Hartl, The Influence of Proteins and Speed on Friction and Adsorption of Metal/UHMWPE Contact Pair, Biotribology, 10.1016/j.biotri.2017.03.003, 11, 51-59, 2017.09, It was reported in several studies that friction and wear of joint prosthesis are apparently influenced by the proteins contained in the synovial fluid. However, detailed mechanisms of these tribological processes have not been clarified yet. The present study aims on the effect of adsorbed protein film on frictional behaviour of metal/polyethylene contact pair. Reciprocating pin-on-plate test was conducted, while the CoCrMo pin was sliding against UHMWPE plate. The contact was lubricated by various solutions of albumin and γ-globulin solved in PBS. After the friction test, the thickness of adsorbed film was evaluated using spectroscopic ellipsometry. Structure of the adsorbed proteins was later examined by FT-IR. The results showed that at low sliding speed equal to 10 mm/s, there was a linear correlation between the friction coefficient and the thickness of the adsorbed protein film. An increase of friction was thus accompanied by the evolution of protein film. In that case, both proteins undergone substantial conformational changes, losing their original structure. On the contrary, proteins could sustain their secondary structure to some extent at higher sliding speed (50 mm/s), when different behaviour of the both proteins could be observed. This phenomenon was attributed to different structure of albumin and γ-globulin in its native state. It might be concluded that friction coefficient of metal-on-polyethylene joint prosthesis is influenced by protein content, as well as kinematic conditions, since the sliding conditions have a certain effect on both the adsorbed film formation and structure of the adsorbed molecules..
5. Keisuke Fukuda, Yoshifumi Shigyo, Hideaki Ariura, Seiji Omata, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Relationship between dynamic stress field and ECM production in regenerated cartilage tissue, 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, 10.1109/MHS.2016.7824183, 2017.01, Mechanical stresses exerted in articular cartilage during daily joint movements can stimulate the metabolism of chondrocytes in cartilage. Upregulative effects of mechanical stimuli on extracellular matrix (ECM) biosynthesis of chondrocytes have been utilized in the cartilage tissue for regenerative tissue engineering. However, dynamic functionalities of these regenerated cartilages were lacked compared with the natural arthrodial cartilage. Natural synovial joint surfaces are contacting and sliding each other. As a result, the loading condition applied to the cartilage tissue is not simple. Under the contact between surfaces, non-uniform stress distribution is exerted in the cartilage tissue. The shear stress at contact area is highly depended on the distance from the surface. Moreover, the surface region is exposed to larger shear stress compared with the deep region. We hypothesized that high stress in surface region may stimulate chondrocytes selectively and establish anisotropic structure in elaborated tissue. In this study, the relative motion between cartilage surfaces in a synovial joint is simulated by the rolling-sliding motion of the roller on the cultured chondrocyte-agarose construct. Then, we investigated effects on the ECM distribution and morphology of regenerated cartilage tissue..
6. Nobuo Sakai, C. Hashimoto, Seido Yarimitsu, Yoshinori Sawae, M. Komori, Teruo Murakami, A functional effect of the superficial mechanical properties of articular cartilage as a load bearing system in a sliding condition, Biosurface and Biotribology, 2016.03.
7. Dipankar Choudhury, Takehiro Morita, Yoshinori Sawae, Juergen M. Lackner, Mark Towler, Ivan Krupka, A novel functional layered diamond like carbon coating for orthopedics applications, DIAMOND AND RELATED MATERIALS, 10.1016/j.diamond.2015.11.011, 61, 56-69, 2016.01.
8. Lei Zhang, Yoshinori Sawae, Teruo Murakami, Hong Yang, Ken Yuki, Investigation of wear and wear particles from shelf-aged crosslinked UHMWPE under
different contact pressures, Triboloby Online, 10.2474/trol.10.404, 10, 6, 404-412, 2015.12.
9. Lei Zhang, Yoshinori Sawae, Tetsuo Yamaguchi, Teruo Murakami, Hong Yang, Effect of radiation dose on depth-dependent oxidation and wear of shelf-aged gamma-irradiated ultra-high molecular weight polyethylene (UHMWPE), TRIBOLOGY INTERNATIONAL, 10.1016/j.triboint.2014.12.011, 89, 78-85, 2015.09.
10. Omata Seiji, Yoshinori Sawae, Teruo Murakami, Effect of poly(vinyl alcohol) (PVA) wear particles generated in water lubricant on immune response of macrophage, Biosurface and Biotribology, 10.1016/j.bsbt.2015.02.003, 1, 71-79, 2015.03, To develop a novel biotribological material for artificial cartilage implant with a lubricity supplement of the joint surface, we focused on two
types of poly(vinyl alcohol) (PVA) hydrogel: repeated freeze–thawing (PVA-FT) and cast-drying (PVA-CD) gels. Here we observed the
morphology of wear particles generated during a reciprocating wear test and assessed macrophage immune responses by applying hydrogel wear
particles. As a result, PVA-CD had a significantly lower total amount of wear than did PVA-FT. The size distributions of PVA-FT and -CD wear
particles were similar. Most of the particles were nanoparticles up to approximately 50 nm in diameter. Considering the particle volume
distribution, there were very few micron- and submicron-sized wear particles around 1 μm in diameter. In SEM observations of dried PVA wear
particles, both distributions of wear particles of PVA-FT and -CD were similar. Micron-sized wear particles were chiefly formed by close packing
of 20- to 50-nm-sized particles. Biochemical and immunological evaluations revealed no cytotoxic effects of wear particles on macrophages.
Cytokine synthesis of both wear particle-stimulated groups was significantly lower than that of the lipopolysaccharide-stimulated positive control.
Therefore, it is suggested that PVA wear particles do not affect the macrophage immune response..
11. Lei Zhang, Yoshinori Sawae, Tetsuo Yamaguchi, Teruo Murakami, Hong Yang, Investigation on oxidation of shelf-aged crosslinked Ultra-High Molecular Weight Polyethylene (UHMWPE) and its effects on wear characteristics, Tribology Online, 10, 1, 1-10, 2015.01.
12. Omata Seiji, Shogo Sonokawa, Yoshinori Sawae, Teruo Murakami, Effects of both vitamin C and mechanical stimulation on improving the mechanical characteristics of regenerated cartilage, 10.1016/j.bbrc.2012.07.019, 424, 4, 724-729, 2012.08.
13. NOBUO SAKAI, Yuichiro Hagihara, Tsukasa Furusawa, Natsuko Hosoda, Yoshinori Sawae, Teruo Murakami, Analysis of biphasic lubrication of articular cartilage loaded by cylindrical indenter, 10.1016/j.triboint.2011.03.016, 46, 2, 225-236, 2012.02.
14. Seiji OMATA, Yoshinori SAWAE, Teruo MURAKAMI, Influence of Ascorbic acid (AsA) Concentration in Culture Medium on Mechanical Property of Regenerated Cartilage, Journal of Environment and Engineering, 6, 416-425, 2011.03.
15. Y. Sawae, K. Fukuda, E. Miyakoshi, S. Doi, H. Watanabe, K. Nakashima, J. Sugimura, Tribological Characterization of Polymeric Sealing Materials in High Pressure Hydrogen Gas, Proceedings of the STLE/ASME 2010 International Joint Tribology Conference, IJTC2010-41238, 2010.10.
16. Influence of phospholipid bilayer on frictional behavior of artificial articular cartilage material.
17. S. Omata, T. Shimizi, Y. Sawae, T. Murakami, Effect of vitamin C on mechanical property of the regenerated-cartilage tissue, IFMBE Proceedings, 31, 899-902, 2010.08.
18. Influence of synovia constituents on frictional behavior of artificial cartilage material and formation of boundary lubricating film.
19. C. Morillo, Y. Sawae and T. Murakami, Effect of bovine serum constituents on the surface of the tribological pair alumina/alumina nanocomposites for total hip replacement, Tribology International, 43, 5月6日, 1158-1162, 2010.05.
20. K. Nakashima, A. Yamaguchi, Y. Kurono, Y. Sawae, T. Murakami and J. Sugimura, Effect of high-pressure hydrogen exposure on wear of polytetrafluoroethylene sliding against stainless steel, Proc. Instn Mech. Engrs Part J, 224, 285-292, 2010.01.
21. Yoshinori SAWAE, Kazuhiro NAKASHIMA, Shunichiro DOI, Teruo MURAKAMI and Joichi SUGIMURA, Effects of High Pressure Hydrogen on Wear of PTFE and PTFE Composite, Proceedings of the ASME/STLE 2009 International Joint Tribology Conference, 2009.10.
22. Yoshinori SAWAE, Daichi YAMAMOTO, Kazuhiro NAKASHIMA, Shunichiro DOI, Teruo MURAKAMI and Joich SUGIMURA, Wear Characteristics of PTFE and PTFE Based Composites in Gaseous Hydrogen, Proceedings of World Tribology Congress 2009, 18, 2009.09.
23. Kazuhiro NAKASHIMA, Yoshie KURONO, Yoshinori SAWAE, Teruo MURAKAMI and Joichi SUGIMURA, Effect of Moisture Content on Wear of PTFE in Hydrogen, Proceedings of World Tribology Congress 2009, 658, 2009.09.
24. Yoshinori SAWAE, Takayuki SARUWATARI, Seido YARIMITSU and Teruo MURAKAMI, Effects of Lubricant Lipid Concentration on Wear Rate of UHMWPE and Characteristics of Wear Particles in Multidirectional Sliding Wear Test, Proceedings of World Tribology Congress 2009, 888, 2009.09.
25. S. Omata, Y. Sawae and T. Murakami, Influence of Ascorbic acid(AsA) concentration in culture medium on mechanical property of regenerated cartilage, Proceedings of World Congress on Medical Physics and Biomedical Engineering, 25, 2009.09.
26. Hiroyoshi TANAKA, Yoshinori SAWAE, Kanao FUKUDA, Shigemasa YAMAGAMI, Takehiro MORITA, Naoshi IZUMI and Joich SUGIMURA, New Experiment System for Sliding Tests in Hydrogen and Surface Analysis with Transfer Vessel, Tribology Online, 4, 4, 82-87, 2009.07.
27. Yoshinori SAWAE, Kazuhiro NAKASHIMA, Akira YAMAGUCHI, Shunichiro DOI, Hiroyoshi TANAKA, Shigemasa YAMAGAMI, Yoshie KURONO, Teruo MURAKAMI, and Joich SUGIMURA, Transfer Film Formation and Wear of PTFE in Gaseous Hydrogen, Extended Abstracts of 2nd International Conference on Advanced Tribology 2008, pp.115-117, 2008.12.
28. Tribology for Functional Tissue Engineering of Articular Cartilage.
29. Yoshinori SAWAE, Akira YAMAGUCHI, Kazuhiro NAKASHIMA, Teruo MURAKAMI and Joichi SUGIMURA, Wear Behavior of Polymeric Sealing Material in Gaseous Hydrogen, Proceedings of STLE/ASME International Joint Tribology Conference, IJTC2008-71225, 2008.10.
30. Seiji OMATA, Yoshinori SAWAE and Teruo MURAKAMI, The Influence of Mechanical Stimulation on the Development of Tissue-Engineered Cartilage, Proceedings of KAIST-Kyushu University Joint Seminar 2008, p.22, 2008.09.
31. Yoshinori Sawae, Akio Yamamoto, Teruo Murakami, Influence of protein and lipid concentration of the test lubricant on the wear of ultra high molecular weight polyethylene, Tribology International, Vol.41, pp.648-656, 2008.07.
32. Yoshinori SAWAE, Akira YAMAGUCHI, Kazuhiro NAKASHIMA, Teruo MURAKAMI, Joichi SUGIMURA, Effects of Hydrogen Atmosphere on Wear Behavior of PTFE Sliding Against Austenitic Stainless Steel, Proceedings of ASME/STLE International Joint Tribology Conference, IJTC2007-44285, 2007.10.
33. Yoshinori SAWAE, Akio YAMAMOTO, Teruo MURAKAMI, Accelerated Wear of UHMWPE for Joint Prosthesis in Physiological Solutions Containing Protein and Lipid, Proceedings of EUROCORR 2007, On CD-ROM, 2007.09.
34. Yoshinori SAWAE, Jun HONDA, Emiko SUZUKI, Yasuyuki MORITA, Masao WATANABE, Toshiyuki SANADA, Teruo MURAKAMI, Experimental Characterization of Regenerated Cartilage Model Cultured under Cyclic Compression, Proceedings of International Conference on Advanced Technology in Experimental Mechanics 2007, On CD-ROM, 2007.09.
35. Yoshinori SAWAE, Tatsuro IKEGAMI, Yasuyuki MATSUSHITA, Nobuo SAKAI, Kiyoshi KOYANO, Teruo MURAKAMI, Cyclic Loading Test of Dental Implant with Mastication Simulator, Proceedings of International Conference on Advanced Technology in Experimental Mechanics 2007, On CD-ROM, 2007.09.
36. The Effect of the Mixing Ratio on the Temporary Cement Retention Force and Seating Discrepancy of Cement-retained Implant Superstructures.
37. Y. Sawae, T. Murakami, T. Sawano, The Influences of Lipid and Protein Concentration on Wear of Ultra-High Molecular Weight Polyethylene, Life Cycle Tribology, Ed. D. Dowson et al., 171-177, 2005.11.
38. T. MURAKAMI, N. SAKAI, Y. SAWAE, K. TANAKA and M. IHARA, Influence of Proteoglycan on Time-Dependent Mechanical Behaviors of Articular Cartilage under Constant Total Compressive Deformation, JSME International Journal, Series C, 10.1299/jsmec.47.1049, 47, 4, 1049-1055, Vol.47, 1049-1055, 2004.12.
39. Y. Sawae, J. Shelton, D.L. Bader and M.M. Knight, Confocal Analysis of Local and Cellular Strains in Chondrocyte-Agarose Constructs Subjected to Mechanical Shear, Annals of Biomedical Engineering, 10.1023/B:ABME.0000030261.38396.c0, 32, 6, 860-870, Vol.32, 860-870, 2004.06.
40. Y. Sawae, T. Murakami, T. Sawano, I. Noda and T. Shimotoso, Surface Characteristics and Tribological Behaviour of New Zirconia Ceramics for Cementless Knee Joint Prostheses, Tribological Research and Design for Engineering Systems, 263-271, 263-271, 2003.09.
Presentations
1. #新盛弘法, 澤江義則, #西村竜成, @Jaswant Kumar Hirwani, 森田健敬, @Sujeet K Sinha, ヒアルロン酸添加エポキシ系樹脂複合材の擬似生体環境における摩耗特性評価, トライボロジー会議2021 春 東京, 2021.05.
2. #李文肖, 森田健敬, 澤江義則, Friction properties of articular cartilage surface lubricated with synovial fluid, トライボロジー会議2021 春 東京, 2021.05.
3. Wenxiao. Li, Takehiro Morita, Yoshinori Sawae, Experimental study on friction properties of articular cartilage surface, 5th International Conference on BioTribology, 2021.04.
4. Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Characteristic tribo-film formation on the polyethylene surface by multidirectional motion and biological macro-molecules, 5th International Conference on BioTribology, 2021.04.
5. David Necas, Hatsuhiko Usami, Tatsuya Niimi, Yoshinori Sawae, Ivan Krupka, Martin Hartl, Reduction of friction in hip joint replacements with the use of surface-textured cup, 5th International Conference on BioTribology, 2021.04.
6. Takumi Sato, Takehiro Morita, Yoshinori Sawae, Evaluation of frictional property of agarose-chondrocyte model using rheometer, 5th International Conference on BioTribology, 2021.04.
7. Yoshinori Sawae, Effect of fillers on friction and wear of PTFE composites in high purity hydrogen gas, 2021 HYDROGENIUS & I2CNER Tribology Symposium, 2021.01.
8. 李文肖, 森田健敬, 山口哲生, 澤江義則, Friction Measurement of Articular cartilage using Nano Tribometer, トライボロジー会議2020 秋 別府, 2020.11.
9. Yoshinori Sawae, Experimental study on synovial joint lubrication using natural articular cartilage and hydrogel cartilage models, Virtual International Tribology Research Symposium 2020, 2020.11, Many previous studies have been conducted to clarify the detailed lubrication mechanism of our synovial joints and to unravel the mystery of extremely smooth joint movements. Sliding surfaces in natural synovial joints are covered with soft and highly hydrated articular cartilage and lubricated with synovial fluid. Despite several different lubrication mechanisms have been proposed, some latest studies are emphasizing the importance of the boundary lubrication at the cartilage surface. However, there are still very active discussions about the lubrication effect of biological molecules contained in the synovial fluid and the cartilage surface, and also the contribution of porous, permeable and hydrated nature of cartilage tissue. In this study, the joint articulation was modeled with glass-on-natural articular cartilage and glass-on-hydrogel cartilage models. Their frictional characteristics was evaluated in the model synovial fluid to explore the boundary lubrication mechanism of the synovial joint.
Square shaped articular cartilage samples (8 mm x 8 mm) were harvested from the proximal end of the bovine middle phalanx within 24h of sacrifice. The frictional characteristics of the cartilage surface was explored by using a smooth glass probe (2 mm diameter) and Nano Tribometer (Anton Paar NTR3) under 5 to 100 mN loads. The cartilage surface was modified by certain treatments and their influence on the frictional behavior was examined.
A synthetic polymer hydrogel, polyvinylalcohol (PVA) hydrogel with 79 wt% water content, was chosen as a simple analogue of articular cartilage to include soft, porous and hydrated nature of the cartilage tissue in the friction test. The frictional behavior between a glass roller and the hydrogel cartilage model was evaluated in reciprocating sliding tests. Representative synovial fluid constituents, such as serum proteins, phospholipids and hyaluronic acid was added to the model synovial fluid and their lubrication effect was examined.
In addition, hydrogel-chondrocytes constructs were prepared as quasi-cartilage models containing living cells. This model was cultured for a few weeks and the evolution of lubrication ability in the cartilage model was monitored through a friction test to examine the contribution of extra cellular matrixes (ECMs) to the boundary lubrication. The characteristic velocity-depended frictional behavior of the hydrogel cartilage model was examined by the rotational rheometer (Anton Paar MCR301).
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10. Hironori Shinmori, Tatsuhiro Hirakawa, Tetsuo Yamaguchi, Yoshitomo Nakata, Yoshinori Sawae, Effect of proteins on frictional behavior of copolymer hydrogels consist of hydrophilic and hydrophobic monomers, International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications, 2019.12.
11. Yoshinori Sawae, Hironori Shinmori, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Lubricity of synovial fluid constituents for artificial joint and synovial joint model, International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications, 2019.12.
12. Yoshinori Sawae, Study on synovial joint lubrication with macroscale experimental models of cartilage tissue and synovial fluid, 10th International Conference on Industrial Tribology, 2019.12.
13. Yoshinori Sawae, Polymer biotribology for evolution of artificial joints, Malaysia-Singapore Research Symposium 2019, 2019.11.
14. Kazuhiro Nakashima, Yoshinori Sawae, Teruo Murakami, Why contact pressure changes frictional property of joint prosthesis material under boundary lubrication?, 3rd Czech-Japan Tribology Workshop, 2019.10.
15. Rui Taninokuchi, Yoshinori Sawae, Keito Sakaki, Takehiro Morita, Joichi Sugimura, Low Friction and Wear of CF Filled PTFE Under High Contact Pressure in Hydrogen, International Tribology Conference Sendai 2019, 2019.09.
16. Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Effect of Synovial Constituents on the Wear of Artificial Joints Materials, International Tribology Conference Sendai 2019, 2019.09.
17. Yuki Doi, Luan Duong Xuan, Yoshinori Sawae, Takehiro Morita, Tetsuo Yamaguchi, Evaluation of Lubrication Effect of ECM Using Agarose-Chondrocyte Complex, International Tribology Conference Sendai 2019, 2019.09.
18. Yoshinori Sawae, Mayo Kubota, Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Evaluation of Lubrication Effect of Protein, Phospholipids and Hyaluronic Acid on Hydrated Hydrogel Cartilage Model, International Tribology Conference Sendai 2019, 2019.09.
19. Keito Sakaki, Takehiro Morita, Rui Taninokuchi, Joichi Sugimura, Yoshinori Sawae, Influence on the Friction Given by Kind of Carbon Fiber Filled PTFE Under Hydrogen Atmosphere, International Tribology Conference Sendai 2019, 2019.09.
20. Tatsuhiro Hirakawa, Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Yoshitomo Nakata, Yoshinori Sawae, Effect of proteins on frictional behavior of copolymer hydrogels consist of hydrophilic and hydrophobic monomers, The 11th International Biotribology Forum, 2019.09.
21. Tetsuo Yamaguchi1, Akira Akamine, Yoshinori Sawae, Adhesion-detachment dynamics of gecko-inspired adhesives, The 11th International Biotribology Forum, 2019.09.
22. Nobuo Sakai, Seido Yarimitsu, Yoshinori Sawae, Saori Sasaki, M. KomoriTeruo Murakami, Effect of unloading period on friction in biphasic lubrication in PVA hydrogel sliding, The 11th International Biotribology Forum, 2019.09.
23. Teruo Murakami, Seido Yarimitsu, Kazuhiro Nakashima, Nobuo Sakai, Saori Sasaki, Yoshinori Sawae, Atsushi Suzuki, Influence of Loading Condition on Frictional Behavior of Poly(Vinyl Alcohol) Hybrid Gel as Artificial Cartilage, The 11th International Biotribology Forum, 2019.09.
24. Jaswant K. Hirwani, Hironori Shinmori, Yoshinori Sawae, Sujeet K. Sinha, Tribological studies of Hyaluronic acid and UHMWPE-filled SU-8 composites, The 11th International Biotribology Forum, 2019.09.
25. Nur Hidayah Binti Shahemi, Shahira Liza binti Kamis, Yoshinori Sawae, Investigations on the influence of graphene-based material fillers on surface properties and lubricated sliding wear behavior of UHMWPE based composite, The 11th International Biotribology Forum, 2019.09.
26. David Nečas, Hatsuhiko Usami, Tatsuya Niimi, Yoshinori Sawae, The effect of acetabular cup surface texturing on friction of hip joint replacements, The 11th International Biotribology Forum, 2019.09.
27. Yoshinori SAWAE, Hironori SHINMORI, Mayo KUBOTA, Tatsuhiro HIRAKAWA, Takehiro MORITA, Tetsuo YAMAGUCHI, Tribological Behavior of Hydrogels in Model Synovial Fluids Containing Proteins, Lipids and Hyaluronic Acid, 10th International Conference on Materials for Advanced Technologies, 2019.06.
28. Hironori Shinmori, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, The Friction and Wear Property of Artificial Joint Materials in Synovial Constituent Solution, 74th STLE Annual Meeting and Exhibition, 2019.05.
29. Takuya Yashiki, Takehiro Morita, Yoshinori Sawae, Tetsuo Yamaguchi, Subsonic to Intersonic Transition in Sliding Contact of Soft Solids, 74th STLE Annual Meeting and Exhibition, 2019.05.
30. Yoshinori Sawae, Mayo Kubota, Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Lubricity of Synovial Fluid Constituents for Hydrogel Cartilage Model, 74th STLE Annual Meeting and Exhibition, 2019.05.
31. Yoshinori Sawae, Lubricity of synovial fluid constituents evaluated on UHMWPE and hydrogel cartilage tissue model, International Symposium on Biosurfaces, Biotribology and Bionic-tribology, 2019.05.
32. Rui Taninokuchi, Keito Sakaki, Takehiro Morita, Yoshinori Sawae, Joichi Sugimura, Low friction of carbon fiber filled PTFE in high-purity hydrogen, 2019 HYDROGENIUS & I2CNER Tribology Symposium, 2019.01.
33. Yoshinori Sawae, Takehiro Morita, Rui Taninoguchi3, Keito Sakaki, Tetsuo Yamaguchi, Joichi Sugimura, Friction and Wear of Carbon Fiber Filled PTFE in High Purity Hydrogen, 2018 International Conference on Engineering Tribology and Applied Technology, 2018.11.
34. TetsuoYamaguchi, Colin Hunt, Yoshinori Sawae, In-situ visualization of transient frictional behavior between Plexiglass, 2018 International Conference on Engineering Tribology and Applied Technology, 2018.11.
35. Yoshinori Sawae, Hironori Shinmori, Mayo Kubota, Tetsuo Yamaguchi, Takehiro Morita, Rheological Characteristics and Lubricity of Model Synovial Fluids containing Protein, Phospholipids and Hyaluronic Acid, 2018 International Conference on Engineering Tribology and Applied Technology, 2018.11.
36. Rui Taninokuchi, Yoshinori Sawae, Reona Umei, Keito Sakaki, Takehiro Morita, Joichi Sugimura, Low Friction of PAN-based Carbon Fiber Filled PTFE in High-purity Hydrogen, 2018 STLE Tribology Frontiers Conference, 2018.10.
37. M. Kubota, H. Shinmori, T. Morita, T. Yamaguchi, Y. Sawae, Lubricity of synovial fluid constituents on highly hydrated hydrogel artificial cartilage, 4th International Conference on BioTribology, 2018.09.
38. T. Murakami, N. Sakai, S. Yarimitsu, K. Nakashima, T. Yamaguchi, Y. Sawae, A. Suzuki, Role of biphasic lubrication in adaptive multimode lubrication mechanism for artificial hydrogel cartilage, 4th International Conference on BioTribology, 2018.09.
39. H. Shinmori, Y. Sawae, M. Kubota, T. Morita, T. Yamaguchi, Effect of proteins and phospholipids for friction between UHMWPE and CoCrMo, 4th International Conference on BioTribology, 2018.09.
40. Yoshinori Sawae, Polymer biotribology, 3rd International Conference on Polymer Tribology, 2018.09.
41. R. Umei, R. Taninoguchi, K. Sakaki, T. Morita, Y. Sawae, J. Sugimura, Effect of trace moisture content on low friction mechanism of carbon fiber filled PTFE, The 6th Asia International Conference on Tribology, 2018.09.
42. H. Shinmori, Y. Sawae, M. Kubota, T. Morita, T. Yamaguchi, Contribution of each synovia constituent to friction of UHMWPE/CoCrMo sliding pair for joint prosthesis, The 6th Asia International Conference on Tribology, 2018.09.
43. Yoshinori Sawae, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Lubricity of synovia constituents on hydrogel artificial cartilage, The 18th Nordic Symposium on Tribology, 2018.06.
44. Mayo Kubota, Hironori Shinmori, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Lubricity of synovial fluid constituents on highly hydrated hydrogel artificial cartilage, The 10th International Biotribology Forum, 2018.03.
45. Teruo Murakami, Nobuo Sakai, Seido Yarimitsu, Kazuhiro Nakashima, Tetsuo Yamaguchi, Yoshinori Sawae, Atsushi Suzuki, Influence of Changes in Permeability on Lubrication Mechanism in Poly(Vinyl Alcohol) Hybrid Gel as Artificial Cartilage, The 10th International Biotribology Forum, 2018.03.
46. Hironori Shinmori, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Protein and phospholipids increase friction between CoCrMo and UHMWPE, The 10th International Biotribology Forum, 2018.03.
47. Yoshinori Sawae, Eiichi Miyakoshi, Shunichiro Doi, Takehiro Morita, Joichi Sugimura, Friction and wear of polymer composites in high pressure hydrogen, 2018 HYDROGENIUS & I2CNER TRIBOLOGY SYMPOSIUM, 2018.02.
48. Reona Umei, Keiji Sakaki, Takehiro Morita, Yoshinori Sawae, Joichi Sugimura, Effect of trace moisture content on low friction mechanism of carbon fiber filled PTFE in high purity hydrogen, 2018 HYDROGENIUS & I2CNER TRIBOLOGY SYMPOSIUM, 2018.02.
49. Naotoshi Shimizu, Yoshinori Sawae, Takehiro Morita, Shugo Onitsuka, Joichi Sugimura, Friction and wear of polymer composites in hydrogen environment at low temperature, 2018 HYDROGENIUS & I2CNER TRIBOLOGY SYMPOSIUM, 2018.02.
50. Hideaki Ariura, Takehiro Morita, Tetsuo Yamaguchi, Yoshinori Sawae, Deformation determination of cultured cell inside scaffolds under mechanical load, Biosurface and Biotribology Chengdu 2017, 2017.09.
51. Yoshinori Sawae1, Ryosuke Baba, Takehiro Morita, Tetsuo Yamaguchi, Teruo Murakami, Effects of serum lubrication on friction between hydrogel acetabular liner and metal head, Biosurface and Biotribology Chengdu 2017, 2017.09.
52. Yoshinori Sawae, Keisuke Fukuda, Yoshifumi Shigyo, Hideaki Ariura, Takehiro Morita, Tetsuo Yamaguchi, Cartilaginous Tissue Formation by Cultured Chondrocytes under Traction loading, World Tribology Congress 2017, 2017.09.
53. Hironori Shinmori、Yoshinori Sawae, Mayo Kubota, Takehiro Morita, Tetsuo Yamaguchi, Effect of Synovial Constituents on Friction between UHMWPE and CoCrMo, 2nd Czech-Japan Tribology Workshop, 2017.11.
54. Mayo Kubota, Yoshinori Sawae, Ryosuke Baba, Takehiro Morita, Tetsuo Yamaguchi, Lubrication Effects of Model Synovial Fluid on Hydrated Hydrogel Artificial Cartilage, 2nd Czech-Japan Tribology Workshop, 2017.11.
55. T.Morita, Y.Sawae, J. Sugimura, EVALUATION OF HYDROGEN GAS SEALING ABILITY OF CARBON , 5th Malaysia-Japan Tribology Symposium 2017, 2017.08.
56. R. Umei, Y. Sawae, T. Morita, LOW FRICTION MECHANISM OF SELF-FORMING CARBON FILM FOR CARBON FIBER FILLED PTFE, 5th Malaysia-Japan Tribology Symposium 2017, 2017.08.
57. H. Ariura, T. Morita, T. Yamaguchi, Y. Sawae, Deformation Determination of Cultured Cells inside Scaffolds under Mechanical Load, 5th Malaysia-Japan Tribology Symposium 2017, 2017.08.
58. Yoshinori Sawae, Biotribology of Natural Synovial Joint and Joint Prosthesis, The Japan Society of Mechanical Engineers Hokkaido Branch “Biomechanics Research Meeting” 29th Seminar, 2017.07, The word “Biotribology” was defined in 1971 to embrace “all aspects of tribology (friction, wear
and lubrication) concerned with biological systems”. It covers many events encountered during our
daily life as research interests, for example, friction between a glass and fingers for gripping, wear of
teeth during brushing and so on. Among them, the lubrication mechanism of natural synovial joint is a
popular research topic in biotribology. The smooth movement of human diarthrodial joints has
attracted huge interests of researchers not only in biomedical filed but also in engineering field, since
the typical friction coefficient of synovial joints is extremely lower, around 0.001, compared with that
of man-made bearing systems, those friction coefficient is usually 0.1 to 0.01. The wear of prosthetic
joint materials is another important issue for biotribology. Metal ions and polymer wear particles
released from sliding surfaces of joint prosthesis implanted in human body are usually very toxic and
exert adverse reactions in the surrounding living tissue Therefore, it is recognized as a main factor
restricting the lifetime of current artificial joints. This presentation attempts to present recent progress
of biotribology research on the natural synovial joint and joint replacements..
59. Y. Sawae,K. Takeda, T. Morita, H. Watanabe,S. Onitsuka,T. Yamaguchi,J. Kaneuchi,J. Sugimura, FRICTION AND WEAR OF PTFE COMPOSITES WITH VARIOUS FILLER MATERIALS IN HIGH PURITY HYDROGEN GAS, 6th European Conference on Tribology , 2017.06.
60. Carbon film formation on the surface of carbon fiber filled PTFE during sliding in High-purity Hydrogen (Second report).
61. Yoshinori Sawae, Polymer Tribology in Hydrogen, 2017 HYDROGENIUS & I2CNER Tribology Symposium, 2017.02.
62. Naotoshi Shimizu, Yasuhiro Shimazu, Junichi Yoshihisa, Yoshinori Sawae, T. Morita, Shugo Onitsuka, Hideki Watanabe, Joichi Sugimura, Friction and Wear of Polymer Composites in Hydrogen Environment at low temperature, 2017 HYDROGENIUS & I2CNER Tribology Symposium, 2017.02.
63. Yoshinori Sawae, Hiroshi Kojima, T. Morita, Kyota Takeda, Hiroyoshi Uejima, Jyo Kaneuti, Joichi Sugimura, Self-forming carbon film lubrication for carbon fibre filled PTFE in high purity hydrogen gas environment, 2017 HYDROGENIUS & I2CNER Tribology Symposium, 2017.02.
64. Ryosuke Baba, Yoshinori Sawae, Tetsuo Yamaguchi, Teruo Murakami, Frictional Characteristics of Hip Joint Prosthesis with Hydrogel Acetabular Liner, ICETA2016, 2016.11.
65. Lei Zhang, Yoshinori Sawae, Teruo Murakami, Hong Yang, Study on the Wear Properties of Shelf-aged Cross-linked and Annealed Ultra-high Molecular Weight Polyethylene (UHMWPE), 2nd Joint Conference of the Research Center for Advanced Biomechanics & Japan Institute of EIectronics Packaging Kyushu Branch, 2014.02.
66. Kazuhiro Nakashima, Yoshinori Sawae, Susumu Kudo, Teruo Murakami, Protein Adsorption Film Observation by Using Electrochemial Method, 2nd Joint Conference of the Research Center for Advanced Biomechanics & Japan Institute of EIectronics Packaging Kyushu Branch, 2014.02.
67. Seido Yarimitsu, Kazuhiro Nakashima, Yoshinori Sawae, Teruo Murakami, Effect of Synovial Fluid Constituents on Tribological Behavior of Artificial Hydrogel Cartilage, 2nd Joint Conference of the Research Center for Advanced Biomechanics & Japan Institute of EIectronics Packaging Kyushu Branch, 2014.02.
68. Omata Seiji, Kohei Matsushita, Keisuke Fukuda, Teruo Murakami, Yoshinori Sawae, Effect of Cyclic Shear Deformation on Viabiiity of Chondrocyte in Regenerated-CartiIage Tissue ModeI, 2nd Joint Conference of the Research Center for Advanced Biomechanics & Japan Institute of EIectronics Packaging Kyushu Branch, 2014.02.
69. Takehiro Morita, Yoshitaka Naganuma, Yoshinori Sawae, Kazumi Okada, Yoshie Kurono, Joichi Sugimura, Hiroyoshi Uejima, Joe Kaneuchi, Friction and Wear of PTFE Composites in Hydrogen under High Temperature and High Sliding Speed Condition, 2014 HYDROGENIUS & I2CNER Tribology Symposium, 2014.01.
70. Hayato Ideguchi, Yoshinori Sawae, Takehiro Morita, Kazuhiro Nakashima, Joichi Sugimura, Effects of Filler Materials in Polymer Composite on Hydrogen Sealing Ability and Wear Characteristics, 2014 HYDROGENIUS & I2CNER Tribology Symposium, 2014.01.
71. Kazumi Okada, Yoshinori Sawae, Takehiro Morita, Joichi Sugimura, Friction and Wear of Carbon Fiber Filled PTFE in Gaseous Hydrogen, 2014 HYDROGENIUS & I2CNER Tribology Symposium, 2014.01.
72. Keisuke Fukuda, Omata Seiji, Yoshinori Sawae, Development of cartilaginous tissue in chondrocyte-agarose construct cultured under traction loading, The 15th International Conference on Biomedical Engineering, 2013.12.
73. Hayato Ideguchi, Yoshinori Sawae, Takehiro Morita, Kazuhiro Nakashima, Joichi Sugimura, Experimental Study of Hydrogen Sealing Ability and Wear Characteristics of Polymer Composites, World Tribology Congress 2013, 2013.09, In this study, the gas sealing ability and wear behavior of polymer composites in gaseous hydrogen were evaluated as the index of sealing parts performance. The experimental results show that differences in the filler materials of PTFE composites and the metal surface roughness affect both hydrogen sealing ability and volumetric wear rate..
74. Yoshinori Sawae, Keisuke Fukuda, Omata Seiji, Traction Loading on Tissue Surface Stimulate Cartilage Tissue Development by Cultured Chondrocytes, World Tribology Congress 2013, 2013.09, In this study, a traction loading was applied to the surface of chondrocyte-agarose construct, a model of regenerative cartilage tissue, and effects on the metabolism of chondrocytes cultured in the agarose construct and subsequent development of cartilage tissue were examined..
75. Kazuhiro Nakashima, Yoshinori Sawae, Teruo Murakami, Stefano Mischler, Behavior of Adsorbed Albumin Film on CoCrMo Alloy under In-situ Observation, World Tribology Congress 2013, 2013.09.
76. Yoshinori Sawae, Ryohei Oide, Takashi Morioka, Effect of Phospholipids on Wear and Friction of Ultra-High Molecular Weight Polyethylene, World Tribology Congress 2013, 2013.09, In this study, effects of phospholipids contained in synovial fluid on the volumetric wear rate and friction coefficient of UHMWPE/Co-Cr-Mo sliding pair were evaluated. In addition, influences on morphological characteristics of polyethylene wear particles were examined too. The multidirectional sliding pin-on-plate wear tester was employed to reproduce the in vivo wear behavior of artificial hip. The reciprocating friction tester was also employed to explore the frictional behavior in detail..
77. 張 磊, 澤江 義則, The Oxidation Behavior and Wear Properties of Shelf-aged Gamma- irradiated UHMWPE, トライボロジー会議2013春 東京, 2013.05.
78. Yoshinori Sawae, Takehiro Morita, Kazuhiro Nakashima, Eichi Miyakoshi, Shunichiro Doi, Hideki Watanabe, Joichi Sugimura, Tribology of Polymer Sealing Materials in Hydrogen, 2013 Hydrogenius Tribology Symposium, 2013.01.
79. keisuke Fukuda, Yoshinori Sawae, Structure and Mechanical Properties of Regenerated Cartilage Tissue Cultured Under Traction Loading, MJIIT-JUC Joint Symposium 2012, 2012.11.
80. Keisuke Fukuda, Yoshinori Sawae, Microscopic Structure Formation in Regenerated Cartilage Tissue Cultured Under Traction Loading, Bio4Apps 2012, 2012.11.
81. Yoshinori Sawae, Kazuhiro Nakashima, Seido Yarimitsu, Teruo Murakami, Interaction Between Physiological Environment and Surface of Joint Prothesis – Effect on Friction and Wear, Bio4Apps 2012, 2012.11.
82. Experimental study of hydrogen sealing ability and wear characteristics of polymer composites.
83. Wear of PTFE in Hydrogen Atmospher.
84. Effects of hydrogen atmosphere on wear behavior of PTFE sliding against austenitic stainless steel.
85. Friction and wear of plastic seal material in hydrogen.
86. Experimental characterization of regenerated cartilage model cultured under cyclic compression.
87. In Situ Observation of Forming Boundary Film Composed of Synovia Constituents on Rubbing Surface of Artificial Cartilage Material.
88. Cyclic loading test of dental implant with mastication simulator.
89. Accelerated wear of UHMWPE for joint prosthesis in physiological solutions containing protein and lipid.
90. Transport phenomena in engineered cartilage with tissue development in agarose gel.
Membership in Academic Society
  • MALAYSIAN TRIBOLOGY SOCIETY
  • The Society of Tribologists and Lubrication Engineers
  • The Japanese Society for Replacement Arthroplasty
  • Japan Society for Design Engineering
  • Japan Society of Mechanical Engineering
  • Japanese Society of Tribologists
  • Japanese Society for Medical and Biological Engineering
  • Japanese Society for Clinical Biomechanics
  • Japanese Society of Oral Implantology
  • Japanese Society for Biomaterials
Awards
  • Effect of Modifying UHMWPE Using Graphene Oxide and Graphite Flakes as Fillers on Protein Adsorption and Wear Behaviour
  • Influence of Proteoglycan on Time-Dependent Mechanical Behaviors of Articular Cartilage under Constant Total Compressive Deformation