Kyushu University Academic Staff Educational and Research Activities Database
Researcher information (To researchers) Need Help? How to update
Ken Yamaura Last modified date:2023.01.25

Undergraduate School

E-Mail *Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
 Reseacher Profiling Tool Kyushu University Pure
Department of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences, Kyushu University .
Academic Degree
Medical Doctor
Country of degree conferring institution (Overseas)
Yes Doctor
Field of Specialization
ORCID(Open Researcher and Contributor ID)
Total Priod of education and research career in the foreign country
Outline Activities
Cardiovascular Anesthesia
Research Interests
  • Anesthetic management in patients with left ventricular dysfunction
    keyword : LV diastolic function, anesthesia
  • Neuropathic pain
    keyword : neuropathic pain
  • postoperative cognitive dysfunction
    keyword : surgery anesthesia cognitive dysfunction
  • Circulation and coagulation control during operative period
    keyword : Circulation coagulation Anesthesia
  • Evaluation of the perioperative cardiac function using transesophageal echocardiaography
    keyword : Transesophageal echocardiography cardiac function perioperqative
    1996.04~2010.03Evaluation of cardiac function using transesophageal echocardiography.
Academic Activities
1. Midoriko Higashi, Kenji Shigematsu, Kenji Tominaga, Kazuya Murayama, Daisuke Seo, Toshikazu Tsuda, Gen Maruta, Kohei Iwashita, Ken Yamaura, Preoperative elevated E/e' (≥ 15) with preserved ejection fraction is associated with the development of postoperative heart failure in intermediate-risk non-cardiac surgical patients., Journal of anesthesia, 10.1007/s00540-019-02728-z, 34, 2, 250-256, 2020.04, PURPOSE: Left ventricular diastolic dysfunction is an independent risk factor for adverse cardiovascular morbidities and mortalities in cardiovascular and high-risk surgical patients. However, there were only a few investigations among intermediate-risk surgical patients. This study aimed to investigate postoperative heart failure (HF) in intermediate-risk surgical patients who had preoperative diastolic dysfunction with preserved ejection fraction (EF). METHODS: Consecutive patients underwent intermediate-risk surgery between January 2016 and December 2018 were retrospectively evaluated. Patients with preserved EF were divided into three groups using one of the parameters of diastolic function: the ratio of early diastolic filling velocity to the peak diastolic velocity of mitral medial annulus (E/e') ≥ 15, E/e' between 8 and 15, and E/e' < 8. Postoperative HF was defined as clinical symptoms and radiological evidence and low SpO2 less than 93%. The primary outcome was the incidence of postoperative HF and its relation to preoperative E/e'. Chi-squared test, unpaired t test with Welch's correction, and multivariate logistic regression were used for analysis. RESULTS: In total, 965 patients were included in the final analysis. Postoperative HF developed in 36/965 (3.7%) patients with preserved EF. The incidence of postoperative HF was stratified according to the E/e', and the rates of HF occurrence in patients with E/e' < 8, 8-15, and ≥ 15 were 1.8%, 2.7%, and 15%, respectively (P < 0.01). CONCLUSION: Preoperative elevated E/e' (≥ 15) was associated with the development of postoperative HF in intermediate-risk surgical patients with preserved EF..
Membership in Academic Society
  • American Society of Anesthesiologists
  • Japanese Society od Medical Instrumentation
  • Japan Association for Perinatal Anestheisolgy
  • 日本麻酔科学会
  • 日本集中治療医学会
  • 日本蘇生学会
  • 日本老年麻酔学会
  • 日本神経麻酔集中治療学会
  • 日本手術医学会
  • 日本心臓血管麻酔学会
  • 日本循環制御医学会
  • 日本区域麻酔学会
  • 日本ペインクリニック学会
  • The Japan Society for Clinical Anesthesia
  • Japanese Society of Medical Instrumentation
  • Japan Society for Obstetric Anesthesia and Perinatology
  • American Society of Anesthesiologist
Educational Activities
Clinical Cardiovascular Anesthesia