Kyushu University Academic Staff Educational and Research Activities Database
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ATSUTA IKIRU Last modified date:2022.06.27

Associate Professor / Division of Advanced Dental Devices and Therapeutics, Faculty of Dental Science Kyushu University
Department of Dental Science
Faculty of Dental Science

Graduate School
Undergraduate School

 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Country of degree conferring institution (Overseas)
Field of Specialization
Dental Prosthesis
Total Priod of education and research career in the foreign country
Outline Activities
Aim of our research: The dental implant treatment has emerged as most important prosthetic therapy option for completely and partially edentulous patients. However, it is a current state that a lot of unsettled matters have been left as for the adhesive mechanism of Peri-implant epithelium and the implant body. Therefore, this research will clarify these matters.
Research Interests
  • Complete denture research
    keyword : Complete denture
  • Injection timing of Mesenchymal Stem Cells to promote the soft tissue sealing around titanium implant
    keyword : Mesenchymal stem cells, Dental implant, Epithelial cell, Titanium, Adhesion molecule
  • Re-generation of Peri-implant epithelium
    keyword : implant epithelium re-generation
Academic Activities
1. 熱田 生, Soft tissue sealing around dental implants based on histological interpretation., J Prosthodont Res, 2016.01.
2. 熱田 生, Therapeutic interaction of systemically-administered mesenchymal stem cells with peri-implant mucosa., PLoS One, 2014.05.
3. ATSUTA IKIRU, IL-17-mediated M1/M2 macrophage alteration contributes to pathogenesis of bisphosphonate-related osteonecrosis of the jaws., Clin Cancer Res., 2013.05.
4. ATSUTA IKIRU, Mesenchymal stem cells inhibit multiple myeloma cells via the Fas-L/Fas pathway, Stem Cell Res Ther, 2013.04.
5. ATSUTA IKIRU, Yasunori AYUKAWA, kiyoshi koyano, The role of phosphoinositide 3-kinase in adhesion of oral epithelial cells to titanium, ARCHIVES OF ORAL BIOLOGY, 10.1016/j.archoralbio.2013.07.013, 58, 11, 1696-1708, 2013.11.
6. ATSUTA IKIRU, Evaluations of epithelial sealing and peri-implant epithelial down-growth around “step-type” implants, 2012.09.
7. ATSUTA IKIRU, Expression of Integrin beta-4 and alpha-3 subunits on the process of peri-implant epithelium formation, 2013.03.
8. ATSUTA IKIRU, In vivo and in vitro studies of epithelial cell behavior around titanium implants with machined- and rough-surface., 2013.01.
9. ATSUTA IKIRU, Promotive effect of insulin-like growth factor-1 for epithelial sealing to titanium implants, 2013.04.
1. ATSUTA IKIRU, Yasunori AYUKAWA, kiyoshi koyano, Mesenchymal stem cells promote soft tissue sealing around titanium implants, 86th Annual Meeting of the American Prosthodontic Society, 2014.02.
2. ATSUTA IKIRU, Yasunori AYUKAWA, kiyoshi koyano, Injection timing of Mesenchymal Stem Cells to promote the soft tissue sealing around titanium implant, Biennial Joint Congress of CPS-JPS-KAP, 2013.04.
3. ATSUTA IKIRU, Inhibitory effects of Mesenchymal Stem Cells for myeloma cells., Seminar in Center for Craniofacial Molecular Biology, 2011.11.
Membership in Academic Society
  • International and American Association for Dental Research
Educational Activities
Other Educational Activities
  • 2015.10.
  • 2013.06.
  • 2009.04.