Kyushu University Academic Staff Educational and Research Activities Database
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Fujii Shinsuke Last modified date:2023.09.20

Lecturer / Maxillofacial Diagnostic & Surgical Sciences
Department of Dental Science
Faculty of Dental Science

Graduate School
Undergraduate School

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 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Country of degree conferring institution (Overseas)
Field of Specialization
Morphological Oral Biology, Oral pathology
Total Priod of education and research career in the foreign country
Research Interests
  • The expression of Arl4c and its function in tumorigenesis.
    keyword : Arl4c, Tumorigenesis
  • The effect of Wnt signaling on salivary gland development.
    keyword : Wnt signaling, salivary gland
  • The effects of TGF-β1 on the proliferation and differentiation of human periodontal ligament cells
    keyword : TGF-β1、periodontal ligament cell
  • Establishment of human periodontal ligament stem/progenitor cell lines and its characterization
    keyword : stem/progenitor cell, periodontal ligament cell
  • Immortalization of human periodontal ligament cells
    keyword : Immortalization. Periodontal ligament
    2003.04~2006.03I established human periodontal ligament progenitor cell lines for the study of regeneration of human periodontal ligament. I am trying to clarify the regeneration mechanism of human periodontal ligament using human periodontal ligament progenitor cell lines..
Academic Activities
1. Nagano, Ryoko; Fujii, Shinsuke; Hasegawa, Kana; Maeda, Hidefumi; Kiyoshima, Tamotsu, Wnt signaling promotes tooth germ development through YAP1-TGF- βsignaling, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 10.1016/j.bbrc.2022.09.012, 630, 64-70, 2022.11.
2. Yurie Mikami, Shinsuke Fujii, Kenichi Kouhashi, Yuichi Yamada, Masafumi Moriyama, Shintarou Kawano, Seiji Nakamura, Yoshinao Oda, Tamotsu Kiyoshima, Low grade myofibroblastic sarcoma arising in the tip of the tongue with intravascular invasion
A case report, Oncology Letters, 10.3892/ol.2018.9115, 16, 3, 3889-3894, 2018.09.
3. Mikami Yurie, Fujii Shinsuke, Kengo Nagata, Hiroko Wada, Kana Hasegawa, Misaki Abe, Reiko U. Yoshimoto, Shintaro Kawano, Seiji Nakamura, Tamotsu Kiyoshima, GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas., J Cancer Res Clin Oncol, 10.1007/s00432-017-2398-2, 143, 8, 1381-1393, 2017.03.
4. Fujii S, Shinjo K, Matsumoto S, Harada T, Nojima S, Sato S, Usami Y, Toyosawa S, Morii E, Kondo Y, Kikuchi A, Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3’-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma, Oncotarget, doi: 10.18632/oncotarget.13147., 6, 49, 81571-81587, 2016.10.
5. Fujii S, Maeda H, Wada N, Tomokiyo A, Saito M, Akamine A, Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo., J Cell Physiol, 215(3):743-749, 2008.03.
6. Shinsuke Fujii., Hidefumi Maeda., Naohisa Wada., Yoshio Kano., Akifumi Akamine. , Establishing and characterizing human periodontal ligament fibroblasts immortalized by SV40T-antigen and hTERT gene transfer., Cell and tissue research, 324巻 117-125頁, 2006.01.
1. Shinsuke Fujii, Abnormality of Signal Network in Oral Tumor, IAOP 2023, 21st International Congress of Oral Pathology and Medicine, 2023.08.
2. Tatsufumi Fujimoto, Shinsuke Fujii, Tamotsu Kiyoshima, Sema3A-AKT Axis In Salivary Gland And Adenoid Cystic Carcinoma Developments, 第68回JADR学術大会, 2020.11.
Membership in Academic Society
Other Educational Activities
  • 2016.05.
  • 2009.11.
  • 2008.11.
  • 2007.11.