Kyushu University Academic Staff Educational and Research Activities Database
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Mitsuru Tanaka Last modified date:2021.09.15

Undergraduate School

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Research and Development Center for Five-Sense Devices, Kyushu University .
Lab. Food Analysis, Department of Bioscience and Biotechnology,
Faculty of Agriculture, Kyushu University .
Academic Degree
Ph.D. (Agriculture)
Country of degree conferring institution (Overseas)
Field of Specialization
Food Analysis
Total Priod of education and research career in the foreign country
Outline Activities
Studies on the evaluation of bioavailability of food compounds and the development of analytical techniques for evaluation of food quality.
Research Interests
  • Application of MALDI-MS Imaging for food analysis
    keyword : MALDI-MS Imaging, Food analysis
  • Study on the synergistic enhancement of small peptide-induced vasorelaxation by food components
    keyword : synergistic effect, peptide, vascular function
  • Study on physiological functionality of small peptides on vascular health and its underlying mechanisms
    keyword : Peptide, Vascular relaxation, Hypertension, Atherosclerosis
Academic Activities
1. Study on the Physiological Benefits of Food Compounds on Vascular Health and Their Underlying Mechanisms.
1. Tae Hun Hahm*, Mitsuru Tanaka*, Huu-Nghi Nguyen, Ayaka Tsutsumi, Koichi Aizawa, Toshiro Matsui (*equal contribution), Matrix-assisted laser desorption/ionization mass spectrometry-guided visualization analysis of intestinal absorption of acylated anthocyanins in Sprague-Dawley rats, Food Chemistry,, 334, 1, 127586, 1-9, 2020.07, [URL].
2. Mitsuru Tanaka, Chung Hsuan, Masataka Oeki, Weilin Shen, Asuka Goda, Yusuke Tahara, Takeshi Onodera, Keisuke Sanematsu, Tomotsugu Rikitake, Eiji Oki, Yuzo Ninomiya, Rintaro Kurebayashi, Hideto Sonoda, Yoshihiko Maehara, Kiyoshi Toko, Toshiro Matsui , Identification of characteristic compounds of moderate volatility in breast cancer cell lines , PLOS ONE,, 15, 6, e0235442, 2020.06.
3. Mitsuru Tanaka, Shinya Dohgu, Genki Komabayashi, Hayato Kiyohara, Fuyuko Takata, Yasufumi Kataoka, Takashi Nirasawa, Motohiro Maebuchi & Toshiro Matsui, Brain-transportable dipeptides across the blood-brain barrier in mice, Scientific Reports,, 9, 5769, 1-10, 2019.04.
4. Huu-Nghi Nguyen*; Tanaka, Mitsuru*; Li, Baorui; Ueno, Tomoya; Matsuda, Hideki; Matsui, Toshiro (*These authors contributed equally), Novel in situ visualisation of rat intestinal absorption of polyphenols via matrix-assisted laser desorption/ionisation mass spectrometry imaging, SCIENTIFIC REPORTS, 10.1038/s41598-019-39405-w, 9, 3166, 1-9, 2019.02.
5. Seong-Min Hong, Mitsuru Tanaka, Riho Koyanagi, Weilin Shen, Toshiro Matsui, Structural Design of Oligo-peptides for Intestinal Transport Model, Journal of Agricultural and Food Chemistry, 10.1021/acs.jafc.6b00279., 64, 10, 2072-2079, 2016.03.
6. Jian Zhao, Aki Suyama, Hsuan Chung, Toshihiko Fukuda, Mitsuru Tanaka, Toshiro Matsui, Ferulic acid enhances nitric oxide production through up-regulation of argininosuccinate synthase in inflammatory human endothelial cells, Life Sciences,, 145, 224-232, 2016.01.
7. Mitsuru Tanaka, Eiji Tanaka, Noe Obinata, Toshiro Matsui, Visualization of Tocopherol Acetate Absorbed Inside Laminated Films by a
Matrix-assisted Laser Desorption/Ionization-imaging Mass Spectrometry, Food Science and Technology Research, doi: 10.3136/fstr.21.821, 21, 6, 821-826, 2015.11.
8. Jian Zhao, Aki Suyama, Mitsuru Tanaka, Toshiro Matsui, Ferulic Acid Enhances the Vasorelaxant Effect of Epigallocatechin Gallate in Tumor Necrosis Factor-Alpha-induced Inflammatory Rat Aorta, The Journal of Nutritional Biochemistry, 10.1016/j.jnutbio.2014.03.013, 25, 7, 807-814, 2014.07.
9. Seong-Min Hong, Mitsuru Tanaka, Saori Yoshii, Toshiro Matsui, Enhanced Visualization of Small Peptides Absorbed in Rat Small Intestine by Phytic-Acid-Aided Matrix-Assisted Laser Desorption/ Ionization-Imaging Mass Spectrometry, Analytical Chemistry, 10.1021/ac402252j, 85, 10033-10039, 2013.09.
10. Mitsuru Tanaka, Jian Zhao, Aki Suyama, and Toshiro Matsui, Epigallocatechin Gallate Promotes the Vasorelaxation Power of the Antiatherosclerotic Dipeptide Trp-His in Contracted Rat Aorta, Journal of Agricultural and Food Chemistry, 10.1021/jf3010228, 60, 9048-9054, 2012, 60, 9048-9054, 2012.09, [URL].
1. Mitsuru Tanaka, Tae Hun Ham, Hun-Nghi Nguyen, Toshiro Matsui, Visualization of absorption and metabolism of polyphenols in rat intestine by nifedipine-aided MALDI-MS imaging, ICoFF/ISNFF2019 (12th International Conference and Exhibition for Nutraceuticals and Functional Foods) Oral presentation, 2019.12.
2. Mitsuru Tanaka, Toshiro Matsui, Screening of synergistic combination of food compounds to exert vasorelaxation effect in rat aorta, ISNFF2017 (The 10th international conference and exhibition on nutraceuticals & functional foods), 2017.10.
3. Seong-Min Hong, Saori Yoshii, Yutaro Morita, Tanaka Mitsuru, Toshiro Matsui, Application of MALDI-MS Imaging to Visualize the Tissue Distribution of Absorbable Small Peptides in Rat Intestine, 2013 International Students Academic Presentation, 2013.03.
Membership in Academic Society
  • The Japanese Society for Food Analysis
  • The Japan Society for Analytical Chemistry
  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • The Japanese Society for Food Science and Technology
  • Japan Society of Nutrition and Food Science
  • Screening of Synergistic Combination of Food Compounds to Exert Vasorelaxation Effect in Rat Aorta
  • Visualization of Tocopherol Acetate Absorbed Inside Laminated Films by a Matrix-assisted Laser Desorption/Ionization-imaging Mass Spectrometry
  • Study on the beneficial effect of food compounds in vascular function