Susumu Kudo | Last modified date:2024.02.13 |
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Homepage
https://kyushu-u.elsevierpure.com/en/persons/susumu-kudo
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http://www.bfe.mech.kyushu-u.ac.jp/
Biofunctional Engineering Laboratory .
Academic Degree
PhD
Country of degree conferring institution (Overseas)
No
Field of Specialization
Biomechanics
Total Priod of education and research career in the foreign country
01years00months
Outline Activities
[Research]
We are elucidating the mechanisms by which the functions of cells and tissues adapt to mechanical environments on the basis of biomechanics. We are also trying to clarify the mechanism and micro- and nanoscopic biotransport. Macroscopic biotransport can be often be analyzed by using a differential equation to model physical phenomena. However, biotransport at much smaller scales (the micro-and nano-scales) is more difficult to model in physical detail. Clarification of the mechanisms of such micro- and nanoscale biotransport will be useful not only in improving our understanding of the mechanisms of disease and the maintenance of stable biological functions, but also for the development of clinical applications such as tissue engineering. The following are examples of the studies that have been performed.
1) Effect of ambient temperature on finger skin blood flow
2) Effect of shear stress on functions of endothelial cells
3) Effect of shear stress on macromolecule permeability across endothelial cells
4) Effect of flow load on hepatic function in co-culture of hepatocytes and endothelial cells
5) Using a photochromic fluorescent protein to analyze membrane protein diffusion in endothelial cells under shear stress
6) Visualization of intracellular diffusion in endothelial cell using photochromic fluorescent protein
[Education]
Undergraduate Course:
Graduate School:
[Social Activities]
N/A
We are elucidating the mechanisms by which the functions of cells and tissues adapt to mechanical environments on the basis of biomechanics. We are also trying to clarify the mechanism and micro- and nanoscopic biotransport. Macroscopic biotransport can be often be analyzed by using a differential equation to model physical phenomena. However, biotransport at much smaller scales (the micro-and nano-scales) is more difficult to model in physical detail. Clarification of the mechanisms of such micro- and nanoscale biotransport will be useful not only in improving our understanding of the mechanisms of disease and the maintenance of stable biological functions, but also for the development of clinical applications such as tissue engineering. The following are examples of the studies that have been performed.
1) Effect of ambient temperature on finger skin blood flow
2) Effect of shear stress on functions of endothelial cells
3) Effect of shear stress on macromolecule permeability across endothelial cells
4) Effect of flow load on hepatic function in co-culture of hepatocytes and endothelial cells
5) Using a photochromic fluorescent protein to analyze membrane protein diffusion in endothelial cells under shear stress
6) Visualization of intracellular diffusion in endothelial cell using photochromic fluorescent protein
[Education]
Undergraduate Course:
Graduate School:
[Social Activities]
N/A
Research
Research Interests
- Effect of ambient temperature on finger skin blood flow
Effect of shear stress on functions of endothelial cells
Effect of shear stress on macromolecule permeability across endothelial cells
Effect of flow load on hepatic function in co-culture of hepatocytes and endothelial cells
Using a photochromic fluorescent protein to analyze membrane protein diffusion in endothelial cells under shear stress
Visualization of intracellular diffusion in endothelial cell using photochromic fluorescent protein
keyword : Biomechanics, Biotransport
2012.04~2023.03.
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