Kyushu University Academic Staff Educational and Research Activities Database
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Hata Jun Last modified date:2024.04.09

Professor / Department of Epidemiology and Public Health
Center for Cohort Studies
Faculty of Medical Sciences

Graduate School
Undergraduate School
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Department of Epidemiology and Public Health, Graduate School of Medical Sciences
Center for Cohort Studies, Graduate School of Medical Sciences .
Academic Degree
Country of degree conferring institution (Overseas)
Field of Specialization
Cerebrovascular disease, Epidemiology
ORCID(Open Researcher and Contributor ID)
Total Priod of education and research career in the foreign country
Outline Activities
Epidemiological studies for chronic diseases (stroke, coronary heart disease, etc.) using the data from the Hisayama Study.
Collaboration of epidemiological and clinical studies (in Kyushu University, domestic, and international stidies).
Lecture of public health for undergraduate students. Education of epidemiological studies for PhD students.
Research Interests
  • Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)
    keyword : Dementia, depression, cohort study
  • The Hisayama Study
    keyword : epidemiology, lifestyle diseases, stroke, coronary heart disease, risk factors
Current and Past Project
  • We investigate the association of sarcopenia with dementia using the follow-up data of the residents of Hisayama, Fukuoka aged 65 years or over.
Academic Activities
1. Hata J, Ninomiya T , Epidemiology of stroke in a general Japanese population: the Hisayama Study
, J Atheroscler Thromb, 2023; 30: 710-719,, 2023.06.
1. Hata J, Tanizaki Y, Kiyohara Y, Kato I, Kubo M, Tanaka K, Okubo K, Nakamura H, Oishi Y, Ibayashi S, Iida M., Ten year recurrence after first ever stroke in a Japanese community: the Hisayama Study, J Neurol Neurosurg Psychiatry, 10.1136/jnnp.2004.038166, 76(3):368-372, 2005.03.
2. Hata J, Matsuda K, Ninomiya T, Yonemoto K, Matsushita T, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Iida M, Kiyohara Y, Nakamura Y, Kubo M., Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction, Hum Mol Genet, 10.1093/hmg/ddm005, 16(6):630-639, 2007.03.
3. Kubo M, Hata J, Doi Y, Tanizaki Y, Iida M, Kiyohara Y., Secular trends in the incidence of and risk factors for ischemic stroke and its subtypes in Japanese population, Circulation, 10.1161/CIRCULATIONAHA.107.743211, 118(25):2672-2678, 2008.12.
4. Hata J, Doi Y, Ninomiya T, Tanizaki Y, Yonemoto K, Fukuhara M, Kubo M, Kitazono T, Iida M, Kiyohara Y., The effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population, Atherosclerosis, 10.1016/j.atherosclerosis.2009.10.044, 210(1):249-255, 2010.05.
5. Hata J, Doi Y, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Hirakawa Y, Kitazono T, Kiyohara Y., Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese: the Hisayama Study, Cerebrovasc Dis, 10.1159/000324392, 31(5):477-484, 2011.01.
6. Hata J, Arima H, Zoungas S, Fulcher G, Pollock C, Adams M, Watson J, Joshi R, Kengne AP, Ninomiya T, Anderson C, Woodward M, Patel A, Mancia G, Poulter N, MacMahon S, Chalmers J, Neal B; ADVANCE Collaborative Group., Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial, PLoS One, 10.1371/journal.pone.0055807, 8(2):e55807, 2013.01.
7. Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y., Secular trends in cardiovascular disease and its risk factors in Japanese: half-century data from the Hisayama Study (1961-2009), Circulation, 10.1161/CIRCULATIONAHA.113.002424, 128(11):1198-1205, 2013.09.
8. Hata J, Arima H, Rothwell PM, Woodward M, Zoungas S, Anderson C, Patel A, Neal B, Glasziou P, Hamet P, Mancia G, Poulter N, Williams B, Macmahon S, Chalmers J; ADVANCE Collaborative Group., Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial, Circulation, 10.1161/CIRCULATIONAHA.113.002717, 128(12):1325-1334, 2013.09.
9. Hata J, Mukai N, Nagata M, Ohara T, Yoshida D, Kishimoto H, Shibata M, Hirakawa Y, Endo M, Ago T, Kitazono T, Oike Y, Kiyohara Y, Ninomiya T., Serum angiopoietin-like protein 2 is a novel risk factor for cardiovascular disease in the community: the Hisayama Study, Arterioscler Thromb Vasc Biol, 10.1161/ATVBAHA.116.307291, 36(8):1686-1691, 2016.08.
10. Hata J, Nagai A, Hirata M, Kamatani Y, Tamakoshi A, Yamagata Z, Muto K, Matsuda K, Kubo M, Nakamura Y; Biobank Japan Cooperative Hospital Group, Kiyohara Y, Ninomiya T., Risk prediction models for mortality in patients with cardiovascular disease: the BioBank Japan project, J Epidemiol, 10.1016/, 27(3S):S71-S76, 2017.03.
11. Hata J, Fukuhara M, Sakata S, Arima H, Hirakawa Y, Yonemoto K, Mukai N, Kitazono T, Kiyohara Y, Ninomiya T., White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study, Hypertens Res, 10.1038/hr.2017.74, 40(11):937-943, 2017.11.
12. Hata J, Ohara T, Katakura Y, Shimizu K, Yamashita S, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Kitazono T, Kuhara S, Ninomiya T., Association between serum β-alanine and risk of dementia, Am J Epidemiol, 10.1093/aje/kwz116, 188(9):1637-1645, 2019.09.
13. Hata J, Nagata T, Sakata S, Oishi E, Furuta Y, Hirakawa Y, Honda T, Yoshida D, Kitazono T, Ninomiya T., Risk prediction model for incident atrial fibrillation in a general Japanese population: the Hisayama Study, Circ J, 10.1253/circj.CJ-20-0794, 85(8):1373-1382, 2021.07, Background: The risk prediction of incident atrial fibrillation (AF) is useful to prevent AF and its complications. The aim of this study is to develop a new risk prediction model for incident AF using the prospective longitudinal data from a general Japanese population.
Methods and Results: A total of 2,442 community-dwelling AF-free residents aged ≥40 years were followed up from 1988 to 2012 (46,422 person-years). The development of AF was confirmed by a standard 12-lead electrocardiogram at repeated health examinations and by medical records at clinics or hospitals. The risk prediction model for incident AF was developed using a Cox proportional hazards model. During the follow up, 230 AF events were confirmed. Age, sex, systolic blood pressure, waist circumference, estimated glomerular filtration rate, abnormal cardiac murmur, high R-wave amplitude, and arrhythmia other than AF were selected for inclusion in the model. This model showed good discrimination (Harrell's c statistics: 0.785) and calibration (Greenwood-Nam-D'Agostino test: P=0.87) for AF risk at 10 years.
Conclusions: The new risk prediction model showed good performance on the individual risk assessment of the future onset of AF in a general Japanese population. As this model included commonly used clinical parameters, it may be useful for determining the requirements for the careful evaluation of AF, such as frequent electrocardiogram examinations in clinical settings, and subsequent reductions in the risk of AF-related complications..
1. Hata J,Kiyohara Y, Diabetes mellitus as a risk factor for cancer: the Hisayama Study, 第72回日本癌学会学術総会, 2013.10.
2. Hata J,Ninomiya T. , Risk factors for carotid atherosclerosis: the Hisayama Study. , 第49回日本動脈硬化学会総会・学術集会, 2017.07.
3. Hata J,Kiyohara Y, Stroke epidemiology in Japan: the Hisayama Study, 2nd Asia Pacific Stroke Conference, 2012.09.
Membership in Academic Society
  • Society for Clinical Epidemiology
  • Japanese Society of Internal Medicine
  • Japan Stroke Society
  • Japanese Circulation Society
  • Japanese Society of Cardiovascular Disease Prevention
  • Japanese Society of Hypertension
  • Japanese Society of Neurology
  • Japan Mibyou Association
  • Japan Epidemiological Association
  • Japanese Society of Public Health
  • Japan Geriatrics Society
  • Japan Atherosclerosis Society
  • American Heart Association
Educational Activities
Lecture of public health.
Education of epidemiological studies using the data from the Hisayama Study and other observational studies