Kyushu University Academic Staff Educational and Research Activities Database
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Higuchi Yujiro Last modified date:2023.04.13

Graduate School
Undergraduate School

 Reseacher Profiling Tool Kyushu University Pure
Web page of Laboratory of Applied Microbiology .
Academic Degree
PhD, Biotechnology
Country of degree conferring institution (Overseas)
Field of Specialization
Applied molecular and cellular physiological microbiology
Total Priod of education and research career in the foreign country
Outline Activities
Study of membrane traffic in Aspergillus oryzae produce valuable materials.
Research Interests
  • Development of Aspergillus oryzae host strains that highly produce valuable materials by cellular biological study
    keyword : Aspergillus oryzae, cellular biology, heterologous protein production
  • Analysis of AipA-like AAA ATPases in eukaryotic microorganisms
    keyword : AAA ATPase, AipA, Aspergillus oryzae, Schizosaccharomyces pombe
  • Analysis of early endosome motility in Aspergillus oryzae
    keyword : Early endosome, Intracellular membrane dynamics, Aspergillus oryzae
Academic Activities
1. Yujiro Higuchi*, Katsuhiko Kitamoto, Traditional and latest researches on Aspergillus oryzae and related Koji molds, Journal of Fungi, 7, 1075, 2021.12.
2. Yujiro Higuchi, Membrane traffic in Aspergillus oryzae and related filamentous fungi, Journal of Fungi, 7, 534, 2021.07.
3. Yujiro Higuchi, Membrane traffic related to endosome dynamics and protein secretion in filamentous fungi, Bioscience, Biotechnology, and Biochemistry, 85, 1038-1045, 2021.04.
4. Yujiro Higuchi, Initial fungal effector production is mediated by early endosome motility, Communicative and Integrative Biology, 2015.05.
5. Yujiro Higuchi*, Gero Steinberg*, Early endosomes motility in filamentous fungi: How and why they move, Fungal Biology Reviews, 2015.05.
6. Yujiro Higuchi, Manabu Arioka, Katsuhiko Kitamoto, Endocytic recycling at the tip region in the filamentous fungus Aspergillus oryzae, Communicative and Integrative Biology, 2009.07.
1. Yuki Morita, Yoshinori Katakura, Kaoru Takegawa, Yujiro Higuchi*, Correlative localization analysis between mRNA and EGFP-fused protein by a single-molecule FISH using an egfp probe in Aspergillus oryzae, Frontiers in Fungal Biology, 2, 721398, 2021.10.
2. Yujiro Higuchi*, Kaoru Takegawa, Single-molecule FISH reveals subcellular localization of α-amylase and actin mRNAs in the filamentous fungus Aspergillus oryzae, Frontiers in Microbiology, 11, 578862, 2020.09.
3. Yujiro Higuchi, Hitomi Matsufuji, Masanari Tanuma, Takatoshi Arakawa, Kazuki Mori, Chihaya Yamada, Risa Shofia, Emiko Matsunaga, Kosuke Tashiro, Shinya Fushinobu, Kaoru Takegawa, Identification and characterization of a novel β-D-galactosidase that releases pyruvylated galactose, Scientific Reports, 8, 12013, 2018.08.
4. Yusuke Togo, Yujiro Higuchi*, Yoshinori Katakura, Kaoru Takegawa, Early endosome motility mediates α-amylase production and cell differentiation in Aspergillus oryzae, Scientific Reports, 7, 15757, 2017.11.
5. Martin Schuster, Magdalena Martin-Urdiroz, Yujiro Higuchi, Christian Hacker, Sreedhar Kilaru, Sarah Gurr, Gero Steinberg, Co-delivery of cell-wall-forming enzymes in the same vesicle for coordinated fungal cell wall formation, Nature Microbiology, 1, 16149, 2016.08.
6. Yujiro Higuchi, Sho Yoshinaga, Ken-ichi Yoritsune, Hiroaki Tateno, Jun Hirabayashi, Shin-ichi Nakakita, Miho Kanekiyo, Yoshimitsu Kakuta, Kaoru Takegawa, A rationally engineered yeast pyruvyltransferase Pvg1p introduces sialylation-like properties in neo-human-type complex oligosaccharide, Scientific Reports, 6, 26349, 2016.05.
7. Ewa Bielska*, Yujiro Higuchi*, Martin Schuster*, Natascha Steinberg, Sreedhar Kilaru, Nicholas J. Talbot, Gero Steinberg, Long-distance endosome trafficking drives fungal effector production during plant infection, Nature Communications, *These authors contributed equally,5, 5097, 2014.10.
8. Yujiro Higuchi, Peter Ashwin, Yvonne Roger, Gero Steinberg, Early endosome motility spatially organizes polysome distribution, Journal of Cell Biology, 204, 3, 343-357, 2014.02.
9. Yujiro Higuchi, Manabu Arioka, Katsuhiko Kitamoto, Functional analysis of the putative AAA ATPase AipA localizing at the endocytic sites in the filamentous fungus Aspergillus oryzae, FEMS Microbiology Letters, 320, 1, 63-71, 2011.07.
10. Yujiro Higuchi, Jun-ya Shoji, Manabu Arioka, Katsuhiko Kitamoto, Endocytosis is crucial for cell polarity and apical membrane recycling in the filamentous fungus Aspergillus oryzae, Eukaryotic Cell, 8, 1, 37-46, 2009.01.
11. Yujiro Higuchi, Tomoyuki Nakahama, Jun-ya Shoji, Manabu Arioka, Katsuhiko Kitamoto, Visualization of the endocytic pathway in the filamentous fungus Aspergillus oryzae using an EGFP-fused plasma membrane protein, Biochemical and Biophysical Research Communications, 340, 3, 784-791, 2006.02.
1. Yujiro Higuchi, Peter Ashwin, Gero Steinberg, The cellular role of early endosome motility in Ustilago maydis., 27th Fungal Genetics Conference, 2013.03.
Membership in Academic Society
  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • The Society for Biotechnology, Japan
  • Fungal Molecular Biology Society of Japan