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Kawakubo Masateru Last modified date：2023.04.21

Assistant Professor / Department of Health Sciences
Faculty of Medical Sciences




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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/masateru-kawakubo
　Reseacher Profiling Tool　Kyushu University Pure
Phone
092-642-6728
Academic Degree
Ph.D.
Field of Specialization
Medical Image Analysis, Medical Image Processing, Medical Data Science
Research
Research Interests
  • Medical Image Analysis
    keyword : Medical Image, Image Analysis, Cardiac Function Analysis, Blood Flow Analysis, Magnetic Resonance Imaging
    2011.04.
Academic Activities
Reports
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1. Arai H, Kawakubo M, Kadokami T, Editorial for: "Image-Based Biological Heart Age Estimation Reveals Differential Aging Patterns Across cardiac chambers", J Magn Reson Imaging, doi: 10.1002/jmri.28687, 2023.03.
2. Arai H, Kawakubo M, Kadokami T, Editorial for: "First-Pass Myocardial Perfusion With Increased Anatomic Coverage at 3T Using Autocalibrated Multiband Imaging", J Magn Reson Imaging, doi: 10.1002/jmri.28213, 2022.04.
3. Arai H, Kawakubo M, Kadokami T, Editorial for: "Right/Left Ventricular Blood Pool T2 Ratio as an Innovative Cardiac MRI Screening Tool for the Identification of Left-to-Right Shunts in Patients with Right Ventricular Disease", J Magn Reson Imaging, doi: 10.1002/jmri.27880, 2021.08.
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Papers
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1. Yamamoto A, Nagao M, Kawakubo M, Ando K, Nakao R, Matsuo Y, Sakai A, Kaneko K, Momose M, Sakai S, Yamaguchi J., Prediction of cardiovascular events using myocardial strain ratio derived from N-13-ammonia positron emission tomography, Eur Radiol., 10.1007/s00330-022-09359-1, 2022.12.
2. Kawakubo M*,**, Waki H**, Shirasaka T, Kojima T, Mikayama R, Hamasaki H, Akamine H, Kato T, Baba S, Ushiro S, Ishigami K. *Corresponding author, **Equal contribution., A deep learning model based on fusion images of chest radiography and X-ray sponge images supports human visual characteristics of retained surgical items detection., Int J Comput Assist Radiol Surg., 10.1007/s11548-022-02816-8, 2022.12.
3. Kawakubo M, Nagao M, Yamamoto A, Nakao R, Matsuo Y, Kaneko K, Watanabe E, Sakai A, Sasaki M, Sakai S, 13 N-ammonia PET-derived right ventricular longitudinal strain and myocardial flow reserve in right coronary artery disease, Eur J Nucl Med Mol Imaging., 10.1007/s00259-021-05647-y, 2021.12.
4. Kawakubo M*, Yamasaki Y, Toyomura D, Yamamura K, Sakamoto I, Moriyama T, Yabuuchi H, Ishigami K, *Corresponding author, Unchanged right ventricular strain in repaired tetralogy of Fallot after pulmonary valve replacement with radial long-axis cine magnetic resonance images, Scientific Reports, 10.1038/s41598-021-98464-0, 11, 1, 2021.09.
5. Kanatani R, Shirasaka T, Kojima T, Kato T, Kawakubo M*. *Corresponding author, Influence of beam hardening in dual- energy CT imaging: phantom study for iodine mapping, virtual monoenergetic imaging, and virtual non-contrast imaging, European Radiology Experimental, https://doi.org/10.1186/s41747-021-00217-1, 5, 18, 2021.04.
6. Yamasaki Y, Abe K, Kamitani T, Hosokawa K, Kawakubo M, Sagiyama K, Hida T, Matsuura Y, Murayama Y, Funatsu R, Tsutsui H, Yabuuchi H., Balloon pulmonary angioplasty improves right atrial reservoir and conduit functions in chronic thromboembolic pulmonary hypertension., European Heart Journal Cardiovascular Imaging, 10.1093/ehjci/jeaa064, 2020.05.
7. M Kawakubo, M Nagao, U Ishizaki, Y Shina, K Inai, Y Yamasaki, M Yoneyama, S Sakai., Feature-Tracking MRI Fractal Analysis of Right Ventricular Remodeling in Adults with Congenitally Corrected Transposition of the Great Arteries, Radiology: Cardiothoracic Imaging, 10.1148/ryct.2019190026, 1, 4, 2019.10.
8. Kawakubo M*, Yamasaki Y, Kamitani T, Sagiyama K, Matsuura Y, Hino T, Abe K, Hosokawa K, Yabuuchi H, and Honda H. *Corresponding author, Clinical usefulness of right ventricular 3D area strain in the assessment of treatment effects of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: comparison with 2D feature-tracking MRI, European Radiology, https://doi.org/10.1007/s00330-019-6008-3, 29, 9, 4583-4592, 2019.09.
9. Kawakubo M*, Nagao M, Kumazawa S, Chishaki AS, Mukai Y, Nakamura Y, Honda H, Morishita J. *Corresponding author, Evaluation of cardiac dyssynchrony with longitudinal strain analysis in 4-chamber cine MR imaging., European Journal of Radiology, 82, 12, 2212-2216, 2013.12.
Presentations
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1. Atsushi Yamamoto, Michinobu Nagao, Masateru Kawakubo, Kiyoe Ando, Risako Nakao, Yuka Matsuo, Akiko Sakai, Mitsuru Momose, Koichiro Kaneko, Kenji Fukushima, Shuji Sakai, Nobuhisa Hagiwara., Ammonia PET-derived Right Ventricular Strain: Prognostic Value in Coronary Artery Disease, SNMMI 2022 Annual Meeting, 2022.06.
2. Atsushi Yamamoto, Michinobu Nagao, Masateru Kawakubo, Kiyoe Ando, Risako Nakao, Yuka Matsuo, Akiko Sakai, Mitsuru Momose, Koichiro Kaneko, Kenji Fukushima, Shuji Sakai, Nobuhisa Hagiwara., Myocardial Energy Estimated by PET Strain and Myocardial Flow Reserve: New Strategy for Coronary Artery Disease, SNMMI 2022 Annual Meeting, 2022.06.
3. Tomohiko Horie, Natsuo Konta, Masateru Kawakubo, Hiroshi Hamano, Han Soo Chang, Tetsu Niwa, Kagayaki Kuroda, Mitsunori Matsumae, Quantitative evaluation of spinal cord cine-MRI with optical flow analysis, Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting, 2022.05.
4. Yurie Shiraia, Masateru Kawakubo, Michinobu Nagao,　Atsushi Yamamota, Yuka Matsuo, Misturu Momose, Risako Nakao, Kenji Fukushima, Masayuki Sasaki, and Shuji Sakai, 13N-ammonia PET-derived myocardial strain: first challenge for patients with coronary artery disease (CyPos賞 Bronze Medal), 第80回日本医学放射線学会, 2021.04.
5. M Kawakubo, M Nagao, A Yamamoto, R Nakao, Y Matsuo, K Fukushima, E Watanabe, A Sakai, M Sasaki, and S Sakai., 13N-アンモニアPETストレイン解析による右室壁運動と心筋血流予備能の関連, 第85回日本循環器学会学術集会, 2021.03.
6. M Kawakubo, M Nagao, A Yamamoto, R Nakao, Y Matsuo, K Fukushima, E Watanabe, A Sakai, M Sasaki, and S Sakai., Potential of Right Ventricular Strain Estimated by 13N-Ammonia PET for the Assessment of Ischemic Cardiomyopathy, The 106th Scientific Assembly & Annual Meeting of the RSNA, 2020.11.
7. M Kawakubo, M Nagao, A Yamamoto, R Nakao, Y Matsuo, K Fukushima, E Watanabe, A Sakai, M Sasaki, and S Sakai., Feature-Tracking of High-Resolution Cine Imaging Derived From 13N-Ammonia PET: Diagnostic Ability of Longitudinal Strain for Detection of Myocardial Ischemia, The 106th Scientific Assembly & Annual Meeting of the RSNA, 2020.11.
8. Feature tracking-derived myocardial strain from 13N-ammonia PET: first challenge for patients with coronary artery disease.
9. Koji Sagiyama, Masateru Kawakubo, Ryohei Funatsu, Takeshi Kamitani, Yuzo Yamasaki, Tomoyuki Hida, Yuko Matsuura, Yuriko Murayama, and Hidetake Yabuuchi, Detecting regional differences of lung motion by optical flow analysis combined with rapid cine MRI using compressed sensing, ISMRM & SMRT VIRTUAL CONFERENCE & EXHIBITION, 2020.08, [URL], The application of cine MRI to lung disease has been technically challenging. In this study, we exploited optical flow analysis combined with rapid acquisition of cine MRI using compressed sensing to detect differences in regional lung motion. The high spatial and temporal resolution and higher signal-to-noise ratio of cine MRI enabled optical flow analysis to visualize regional differences between five lung segments. It also differentiated between chest and diaphragm breathing patterns in volunteers. In the future, this non-invasive method could be applied to assess and follow lung diseases, such as interstitial pneumonia or chronic obstructive pulmonary disease..
10. M. Kawakubo, M. Nagao, K. Fukushima, E. Watanabe, A. Sakai, S. Suzaki, Y. Shimomiya, S. Sakai, CT instantaneous wave-free ratio (iFR) for detecting functional coronary stenosis using whole heart dynamic imaging with dose modulated scan, European Congress of Radiology, 2020.07.
11. M. Kawakubo, M. Nagao, R. Nakao, E. Watanabe, M. Yoneyama, N. Hagiwara, S. Sakai, Association between decelerated dark flow in steady-state free precession cine cardiac MR imaging and left ventricular myocardial functions, European Congress of Radiology, 2020.07.
12. Decelerated dark flow with steady-state free precession cine CMR imaging: Association with left ventricular myocardial strain and dyssynchrony.
13. Tsukasa Kojima, Michinobu Nagao, Takashi Shirasaka, Masateru Kawakubo, Yamato Shimomiya, Yuzo Yamasaki, Toyoyuki Kato, Shuji Sakai., Hybrid analysis of transluminal attenuation gradient and dynamic 320-detector coronary CT angiography: detection of functional coronary stenosis, European Congress of Radiology, 2019.03.
14. H Arai, M Kawakubo, M Eguchi, K Sanui, H Nishimura, and T Kadokami., How to quantify the intramyocardial hemorrhage after reperfusion injury: comparison to various semi-automatically methods, The 104th Scientific Assembly & Annual Meeting of the RSNA, 2018.11.
15. Arai H, Kawakubo M, Sanui K, Nishimura H, Kadokami T., Superiority of systolic T1 mapping with saturation recovery for errors of image registration and identification of myocardium, The 104th Scientific Assembly & Annual Meeting of the RSNA, 2018.11.
16. Kawakubo M, Fukushima K, Nakao R, Watanabe E, Shimomiya Y, Goto Y, Tadenuma H, Yoneyama M, Nagao M, Vortex flow in left ventricle interrupts efficient ejection: Demonstration by vortex flow map of cardiac cine magnetic resonance imaging, ISMRM 26th Annual Meeting & Exhibition, 2018.06.
17. Kawakubo M, Fukushima K, Nakao R, Shimomiya Y, Goto Y, Tadenuma H, Yoneyama M, Morishita J, Nagao M, Geometrical Vortex Flow in Left Ventricle Associates with Efficient Ejection: Analysis of a Novel Vortex Flow Map of 2D Cine MRI, The 45th Annual Meeting of Japanese Society of Magnetic Resonance in Medicine, 2017.09.
18. Kawakubo M, Yamasaki Y, Akamine H, Nagao M, Three-dimensional Bi-ventricular Myocardial Feature Tracking for Congenital Heart Disease Using Standard Cardiac Cine MRI with Interpolation Technique Based on Moving Gradients, ISMRM 25th Annual Meeting & Exhibition, 2017.04.
19. Kawakubo M, Yamasaki Y, Sakamoto I, Yamamura K, Nagao M, Biventricular Strain and Torsion in Adults with Corrected Transposition of the Great Arteries Analyzed by Feature Tracking Cine MRI, The 102nd Scientific Assembly & Annual Meeting of the RSNA, 2016.11.
20. Kawakubo M, Nagao M, Kumazawa S, Yonezawa M, Yamasaki Y, Honda H, Chishaki AS, Nakamura Y, Morishita J, Semi-automatic Cardiac Longitudinal Strain Analysis Using Four-chamber Cine MR Imaging: Correlation with Left Ventricular Dysfunction, The 100th Scientific Assembly & Annual Meeting of the RSNA, 2014.12.
21. Kawakubo M, Nagao M, Kumazawa S, Chishaki AS, Honda H, Morishita J, Evaluation of Cardiac Mechanical Dyssynchrony with Longitudinal Strain Analysis in 4-chamber Cine Magnetic Resonance Imaging, ISMRM 20th Annual Meeting & Exhibition, 2012.05.
22. Kawakubo M, Nagao M, Kumazawa S, Chishaki AS, Honda H, Morishita J, Evaluation of Cardiac Mechanical Dyssynchrony Using 4-chamber Cine Magnetic Resonance Imaging: Assessment of Chronic Heart Failure, European Congress of Radiology, 2012.03.
Membership in Academic Society
  • American Society of Nuclear Cardiology
  • Japanese Society of Nuclear Cardiology (JSNC)
  • The Japanese Circulation Society (JCS)
  • Japanese Society for Magnetic Resonance in Medicine (JSMRM)
  • Japanese Society for Adult Congenital Heart Disease (JSACHD)
  • Japanese Society of Radiological Technology (JSRT)
  • The Japanese Association of Radiological Technologist (JART)
Awards
  • Vortex Flow in Left Ventricle Interrupts Efficient Ejection: Demonstration by Vortex Flow Map of Cardiac Cine Magnetic Resonance Imaging
  • Assessment of Sleep Apnea Syndrome using Airway Cine MRI
  • Evaluation of cardiac mechanical dyssynchrony with four chamber cine magnetic resonance imaging
  • Evaluation of cardiac mechanical dyssynchrony using 4-chamber cine magnetic resonance imaging: Assessment of chronic heart failure


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