| Kunimasa Ohta | Last modified date：2023.09.26 |
Professor /
Stem Cell Biology /
Division for Experimental Natural Science /
Faculty of Arts and Science
Papers
| 1. | Arif Istiaq, Terumasa Umemoto, Naofumi Ito, Toshio Suda, Kenji Shimamura, and Kunimasa Ohta, Tsukushi proteoglycan maintains RNA splicing and developmental signaling network in GFAP-expressing subventricular zone neural stem/progenitor cells, Frontiers in Cell and Developmental Biology, 10.3389/fcell.2022.994588, 2022.11, [URL]. |
| 2. | Siyaporn Putthisen, Atit Silsirivanit, Orasa Panawan, Akiko Niibori-Nambu, Yuki Nishiyama-Ikeda, Prasertsri Ma-In, Sukanya Luang, Kunimasa Ohta, Kanha Muisuk, Sopit Wongkham, Norie Araki, Targeting alpha 2,3-sialylated glycan in glioma stem-like cells by Maackia amurensis lectin-II: A promising strategy for glioma treatment, Experimental Cell Research, 410, 1, 112949, 2022.01. |
| 3. | Yuki Shirakawa, Kunimasa Ohta, Shunsuke Miyake, Ayumi Kanemaru, Akari Kuwano, Kou Yonemaru, Shota Uchino, Michiko Yamaoka, Yuki Ito, Naofumi Ito, Takuichiro Hide, Naoki Shinojima, Akitake Mukasa, Hideyuki Saito, and Hirofumi Jono, Glioma Cells Acquire Stem-like Characters by Extrinsic Ribosome Stimuli, Cells, 10, 11, 2970, 2021.11, [URL]. |
| 4. | Miwa, T., Ito, N., and Ohta, K., Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance, J Cell Commun Signal., 10.1007/s12079-021-00627-1, 2021.06, [URL]. |
| 5. | N. Ito, M. A. Riyadh, S. A. I. Ahmad, S. Hattori, Y. Kanemura, H. Kiyonari, T. Abe, Y. Furuta, Y. Shinmyo, N. Kaneko, Y. Hirota, G. Lupo, J. Hatakeyama, F. A. Abdulhaleem M, M. B. Anam, T. Yamaguchi, T. Takeo, H. Takebayashi, M. Takebayashi, Y. Oike, N. Nakagata, K. Shimamura, M. J. Holtzman, Y. Takahashi, F. Guillemot, K. Miyakawa, K. Sawamoto, and K. Ohta, Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone, Science Translational Medicine, DOI: 10.1126/scitranslmed.aay7896, 13, 587, eaay7896, 2021.03, [URL], The lateral ventricle (LV) is flanked by the subventricular zone (SVZ), a neural stem cell (NSC) niche rich in extrinsic growth factors regulating NSC maintenance, proliferation and neuronal differentiation. Dysregulation of the SVZ niche causes LV expansion, a condition known as hydrocephalus; however, the underlying pathological mechanisms areis unclear. We show that deficiency of the proteoglycan Tsukushi (TSK) in ependymal cells at the LV surface and in the cerebrospinal fluid (CSF) results in hydrocephalus with neurodevelopmental disorder-like symptoms in mice. These symptoms are accompanied by altered differentiation and survival of the NSC lineage, disrupted ependymal structure and dysregulated Wnt signaling. Multiple TSK variants found in patients with hydrocephalus patients exhibit reduced physiological activity in mice in vivo and in vitro. Administration of wild-type TSK protein or Wnt antagonists, but not of hydrocephalus-related TSK variants, in the LV of TSK knockout mice preventeds hydrocephalus and preserveds SVZ neurogenesis. These observations reveal suggest that TSK plays a crucial role for TSK as a niche molecule modulating the fate of SVZ NSCs and point to TSK as a candidate for the diagnosis and therapy of hydrocephalus.. |
| 6. | Mohammad Badrul Anam, Arif Istiaq, Ryusho Kariya, Mikiko Kudo, Shah Adil Ishtiyaq Ahmad, Naofumi Ito, Seiji Okada, and Kunimasa Ohta, Ribosome induces transdifferentiation of A549 and H-111-TC cancer cell lines, Biochemistry and Biophysics Reports, https://doi.org/10.1016/j.bbrep.2021.100946, 2021.02. |
| 7. | Kudo M., Anam M.B., Istiaq A., Ahmad S.A.I., Ito N., and Ohta K., Induces EMT-like Phenomenon with Cell Cycle Arrest in Human Breast Cancer Cell, Cells Tissues Organs, doi.org/10.1159/000513908, 2021.02. |
| 8. | Yuki Shirakawa, Takuichiro Hide, Michiko Yamaoka, Yuki Ito, Naofumi Ito, Kunimasa Ohta, Naoki Shinojima, Akitake Mukasa, Hideyuki Saito, Hirofumi Jono, Ribosomal protein S6 promotes stem-like characters in glioma cells., Cancer science, 10.1111/cas.14399, 111, 6, 2041-2051, 2020.06, Glioblastoma multiforme (GBM), a lethal brain tumor developing in the white matter of the adult brain, contains a small population of GBM stem cells (GSCs), which potentially cause chemotherapeutic resistance and tumor recurrence. However, the mechanisms underlying the pathogenesis and maintenance of GSCs remain largely unknown. A recent study reported that incorporation of ribosomes and ribosomal proteins into somatic cells promoted lineage trans-differentiation toward multipotency. This study aimed to investigate the mechanism underlying stemness acquisition in GBM cells by focusing on 40S ribosomal protein S6 (RPS6). RPS6 was significantly upregulated in high-grade glioma and localized at perivascular, perinecrotic, and border niches in GBM tissues. siRNA-mediated RPS6 knock-down significantly suppressed the characteristics of GSCs, including their tumorsphere potential and GSC marker expression; STAT3 was downregulated in GBM cells. RPS6 overexpression enhanced the tumorsphere potential of GSCs and these effects were attenuated by STAT3 inhibitor (AG490). Moreover, RPS6 expression was significantly correlated with SOX2 expression in different glioma grades. Immunohistochemistry data herein indicated that RPS6 was predominant in GSC niches, concurrent with the data from IVY GAP databases. Furthermore, RPS6 and other ribosomal proteins were upregulated in GSC-predominant areas in this database. The present results indicate that, in GSC niches, ribosomal proteins play crucial roles in the development and maintenance of GSCs and are clinically associated with chemoradioresistance and GBM recurrence.. |
| 9. | Toru Miwa, Kunimasa Ohta, Naofumi Ito, Satoko Hattori, Tsuyoshi Miyakawa, Toru Takeo, Naomi Nakagata, Wen Jie Song, Ryosei Minoda, Tsukushi is essential for the development of the inner ear, Molecular Brain, 10.1186/s13041-020-00570-z, 13, 1, 2020.03. |
| 10. | Mohammad Badrul Anam, Shah Adil Ishtiyaq Ahmad, Mikiko Kudo, Arif Istiaq, Athary Abdulhaleem M. Felemban, Naofumi Ito, Kunimasa Ohta, Akhirin regulates the proliferation and differentiation of neural stem cells/progenitor cells at neurogenic niches in mouse brain, Development Growth and Differentiation, 10.1111/dgd.12646, 62, 2, 97-107, 2020.02. |
| 11. | Shah Adil Ishtiyaq Ahmad, Mohammad Badrul Anam, Arif Istiaq, Naofumi Ito, Kunimasa Ohta, Tsukushi is essential for proper maintenance and terminal differentiation of mouse hippocampal neural stem cells, Development Growth and Differentiation, 10.1111/dgd.12649, 62, 2, 108-117, 2020.02. |
| 12. | Tatsuya Yamada, Kunimasa Ohta, Yamato Motooka, Kosuke Fujino, Shinji Kudoh, Yuki Tenjin, Younosuke Sato, Akira Matsuo, Koei Ikeda, Makoto Suzuki, Takaaki Ito, Significance of Tsukushi in lung cancer, Lung Cancer, 10.1016/j.lungcan.2019.03.024, 131, 104-111, 2019.05. |
| 13. | Kunimasa Ohta, Eriko Aoyama, Shah Adil Ishtiyaq Ahmad, Naofumi Ito, Mohammad Badrul Anam, Satoshi Kubota, Masaharu Takigawa, CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi, Journal of Cell Communication and Signaling, 10.1007/s12079-018-0487-x, 13, 1, 113-118, 2019.03. |
| 14. | Qiuyu Wang, Vishal P. Sharma, Hong Shen, Yuanyuan Xiao, Qi Zhu, Xuelian Xiong, Liang Guo, Lin Jiang, Kunimasa Ohta, Siming Li, Haifei Shi, Liangyou Rui, Jiandie D. Lin, The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation, Nature Metabolism, 10.1038/s42255-018-0020-9, 1, 2, 251-260, 2019.02. |
| 15. | Naofumi Ito, Kaoru Katoh, Hiroko Kushige, Yutaka Saito, Terumasa Umemoto, Yu Matsuzaki, Hiroshi Kiyonari, Daiki Kobayashi, Minami Soga, Takumi Era, Norie Araki, Yasuhide Furuta, Toshio Suda, Yasuyuki Kida, Kunimasa Ohta, Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency, Scientific reports, 10.1038/s41598-018-20057-1, 8, 1, 2018.12, Recently, we reported that bacterial incorporation induces cellular transdifferentiation of human fibroblasts. However, the bacterium-intrinsic cellular- transdifferentiation factor remained unknown. Here, we found that cellular transdifferentiation is caused by ribosomes. Ribosomes, isolated from both prokaryotic and eukaryotic cells, induce the formation of embryoid body-like cell clusters. Numerous ribosomes are incorporated into both the cytoplasm and nucleus through trypsin-activated endocytosis, which leads to cell-cluster formation. Although ribosome-induced cell clusters (RICs) express several stemness markers and differentiate into derivatives of all three germ layers in heterogeneous cell populations, RICs fail to proliferate, alter the methylation states of pluripotent genes, or contribute to teratoma or chimera formation. However, RICs express markers of epithelial–mesenchymal transition without altering the cell cycle, despite their proliferation obstruction. These findings demonstrate that incorporation of ribosomes into host cells induces cell transdifferentiation and alters cellular plasticity.. |
| 16. | Md Safiqul Islam, Fan Yan Wei, Kunimasa Ohta, Naoki Shigematsu, Takaichi Fukuda, Kazuhito Tomizawa, Tatsuya Yoshizawa, Kazuya Yamagata, Sirtuin 7 is involved in the consolidation of fear memory in mice, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2017.10.159, 495, 1, 261-266, 2018.01. |
| 17. | Kosei Yano, Kaoru Washio, Yuka Tsumanuma, Masayuki Yamato, Kunimasa Ohta, Teruo Okano, Yuichi Izumi, The role of Tsukushi (TSK), a small leucine-rich repeat proteoglycan, in bone growth, Regenerative Therapy, 10.1016/j.reth.2017.08.001, 7, 98-107, 2017.12. |
| 18. | Rie Kawano, Kunimasa Ohta, Giuseppe Lupo, Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning, Open Biology, 10.1098/rsob.170225, 7, 12, 2017.01. |
| 19. | Uzzal Kumar Acharjee, Ryu Gejima, M. Felemban Athary Abdulhaleem, M. Asrafuzzaman Riyadh, Hideaki Tanaka, Kunimasa Ohta, Tsukushi expression is dependent on Notch signaling and oscillated in the presomitic mesoderm during chick somitogenesis, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2015.08.074, 465, 3, 625-630, 2015.09. |
| 20. | Felemban Athary Abdulhaleem M, Xiaohong Song, Rie Kawano, Naohiro Uezono, Ayako Ito, Giasuddin Ahmed, Mahmud Hossain, Kinichi Nakashima, Hideaki Tanaka, Kunimasa Ohta, Akhirin regulates the proliferation and differentiation of neural stem cells in intact and injured mouse spinal cord, Developmental Neurobiology, 10.1002/dneu.22238, 75, 5, 494-504, 2015.05. |
| 21. | Yohei Shinmyo, M. Asrafuzzaman Riyadh, Giasuddin Ahmed, Iftekhar Bin Naser, Mahmud Hossain, Hirohide Takebayashi, Hiroshi Kawasaki, Kunimasa Ohta, Hideaki Tanaka, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex, Nature communications, 10.1038/ncomms10232, 6, 2015.01. |
| 22. | Daisuke Niimori, Rie Kawano, Kanako Niimori-Kita, Hironobu Ihn, Kunimasa Ohta, Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors, Journal of Cell Communication and Signaling, 10.1007/s12079-014-0241-y, 8, 3, 173-177, 2014.09. |
| 23. | M. Asrafuzzaman Riyadh, Yohei Shinmyo, Kunimasa Ohta, Hideaki Tanaka, Inhibitory effects of draxin on axonal outgrowth and migration of precerebellar neurons, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2014.05.013, 449, 1, 169-174, 2014.06. |
| 24. | Xiaohong Song, Yuya Sato, Kiyotoshi Sekiguchi, Hideaki Tanaka, Kunimasa Ohta, Equarin Is Involved in Cell Adhesion by Means of Heparan Sulfate Proteoglycan During Lens Development, Developmental Dynamics, 10.1002/dvdy.23921, 242, 3, 301, 2013.03. |
| 25. | Shogo Ninomiya, Shigeyuki Esumi, Kunimasa Ohta, Takaichi Fukuda, Tetsufumi Ito, Itaru Imayoshi, Ryoichiro Kageyama, Toshio Ikeda, Shigeyoshi Itohara, Nobuaki Tamamaki, Amygdala kindling induces nestin expression in the leptomeninges of the neocortex, Neuroscience Research, 10.1016/j.neures.2012.12.006, 75, 2, 121-129, 2013.02. |
| 26. | Mahmud Hossain, Giasuddin Ahmed, Iftekhar Bin Naser, Yohei Shinmyo, Ayako Ito, M. Asrafuzzaman Riyadh, Athary Felemban, Xiaohong Song, Kunimasa Ohta, Hideaki Tanaka, The combinatorial guidance activities of draxin and Tsukushi are essential for forebrain commissure formation, Developmental Biology, 10.1016/j.ydbio.2012.11.029, 374, 1, 58-70, 2013.02. |
| 27. | Xiaohong Song, Yuya Sato, Kiyotoshi Sekiguchi, Hideaki Tanaka, Kunimasa Ohta, Equarin is involved in cell adhesion by means of heparan sulfate proteoglycan during lens development, Developmental Dynamics, 10.1002/dvdy.23902, 242, 1, 23-29, 2013.01. |
| 28. | Kunimasa Ohta, Rie Kawano, Naofumi Ito, Lactic Acid Bacteria Convert Human Fibroblasts to Multipotent Cells, PloS one, 10.1371/journal.pone.0051866, 7, 12, 2012.12. |
| 29. | Daisuke Niimori, Rie Kawano, Athary Felemban, Kanako Niimori-Kita, Hideaki Tanaka, Hironobu Ihn, Kunimasa Ohta, Tsukushi controls the hair cycle by regulating TGF-Β1 signaling, Developmental Biology, 10.1016/j.ydbio.2012.08.030, 372, 1, 81-87, 2012.12. |
| 30. | Xiaohong Song, Yuya Sato, Athary Felemban, Ayako Ito, Mahmud Hossain, Hiroshi Ochiai, Takashi Yamamoto, Kiyotoshi Sekiguchi, Hideaki Tanaka, Kunimasa Ohta, Equarin is involved as an FGF signaling modulator in chick lens differentiation, Developmental Biology, 10.1016/j.ydbio.2012.05.029, 368, 1, 109-117, 2012.08. |
| 31. | Giasuddin Ahmed, Yohei Shinmyo, Kunimasa Ohta, Shahidul M. Islam, Mahmud Hossain, Iftekhar Bin Naser, M. Asrafuzzaman Riyadh, Yuhong Su, Sanbing Zhang, Marc Tessier-Lavigne, Hideaki Tanaka, Draxin inhibits axonal outgrowth through the netrin receptor dcc, Journal of Neuroscience, 10.1523/JNEUROSCI.0943-11.2011, 31, 39, 14018-14023, 2011.09. |
| 32. | Kunimasa Ohta, Ayako Ito, Sei Kuriyama, Giuseppe Lupo, Mitsuko Kosaka, Shin Ichi Ohnuma, Shinichi Nakagawa, Hideaki Tanaka, Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4, Proceedings of the National Academy of Sciences of the United States of America, 10.1073/pnas.1100513108, 108, 36, 14962-14967, 2011.09. |
| 33. | Ayako Ito, Yohei Shinmyo, Takaya Abe, Naoko Oshima, Hideaki Tanaka, Kunimasa Ohta, Tsukushi is required for anterior commissure formation in mouse brain, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2010.10.127, 402, 4, 813-818, 2010.11. |
| 34. | Momoko Hayashida, Ryosei Minoda, Yohei Shinmyo, Kunimasa Ohta, Hideaki Tanaka, Eiji Yumoto, PC3 is involved in the shift from proliferation to differentiation and maturation in spiral ganglion neurons, NeuroReport, 10.1097/WNR.0b013e328332c4d7, 21, 2, 90-93, 2010.04. |
| 35. | Asaka Uejima, Takanori Amano, Naoki Nomura, Miyuki Noro, Taiji Yasue, Toshihiko Shiroishi, Kunimasa Ohta, Hitoshi Yokoyama, Koji Tamura, Anterior shift in gene expression precedes anteriormost digit formation in amniote limbs, Development Growth and Differentiation, 10.1111/j.1440-169X.2009.01161.x, 52, 2, 223-234, 2010.02. |
| 36. | Shahidul M. Islam, Yohei Shinmyo, Tatsuya Okafuji, Yuhong Su, Iftekhar Bin Naser, Giasuddin Ahmed, Sanbing Zhang, Sandy Chen, Kunimasa Ohta, Hiroshi Kiyonari, Takaya Abe, Satomi Tanaka, Ryuichi Nishinakamura, Toshio Terashima, Toshio Kitamura, Hideaki Tanaka, Draxin, a repulsive guidance protein for spinal cord and forebrain commissures, Science, 10.1126/science.1165187, 323, 5912, 388-393, 2009.01. |
| 37. | Samantha A. Morris, Alexandra D. Almeida, Hideaki Tanaka, Kunimasa Ohta, Shin Ichi Ohnuma, Tsukushi modulates Xnr2, FGF and BMP signaling Regulation of Xenopus germ layer formation, PloS one, 10.1371/journal.pone.0001004, 2, 10, 2007.10. |
| 38. | Kunimasa Ohta, Sei Kuriyama, Tatsuya Okafuji, Ryu Gejima, Shin Ichi Ohnuma, Hideaki Tanaka, Tsukushi cooperates with VG1 to induce primitive streak and Hensen's node formation in the chick embryo, Development, 10.1242/dev.02579, 133, 19, 3777-3786, 2006.10. |
| 39. | Sei Kuriyama, Giuseppe Lupo, Kunimasa Ohta, Shin Ichi Ohnuma, William A. Harris, Hideaki Tanaka, Tsukushi controls ectodermal patterning and neural crest specification in Xenopus by direct regulation of BMP4 and X-delta-1 activity, Development, 10.1242/dev.02178, 133, 1, 75-88, 2006.01. |
| 40. | Mansoor Ahsan, Kunimasa Ohta, Sei Kuriyama, Hideaki Tanaka, Novel soluble molecule, Akhirin, is expressed in the embryonic chick eyes and exhibits heterophilic cell-adhesion activity, Developmental Dynamics, 10.1002/dvdy.20303, 233, 1, 95-104, 2005.05. |
| 41. | Kunimasa Ohta, Giuseppe Lupo, Sei Kuriyama, Roger Keynes, Christine E. Holt, William A. Harris, Hideaki Tanaka, Shin Ichi Ohnuma, Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin, Developmental Cell, 10.1016/j.devcel.2004.08.014, 7, 3, 347-358, 2004.09. |
| 42. | Christopher N.G. Anderson, Kunimasa Ohta, Marie M. Quick, Angeleen Fleming, Roger Keynes, David Tannahill, Molecular analysis of axon repulsion by the notochord, Development, 10.1242/dev.00327, 130, 6, 1123-1133, 2003.03. |
| 43. | Hong Mu, Kunimasa Ohta, Sei Kuriyama, Naoko Shimada, Hidenobu Tanihara, Kunio Yasuda, Hideaki Tanaka, Equarin, a novel soluble molecule expressed with polarity at chick embryonic lens equator, is involved in eye formation, Mechanisms of Development, 10.1016/S0925-4773(02)00423-9, 120, 2, 143-155, 2003.02. |
| 44. | T. Yamada, T. Okafuji, K. Ohta, C. Handwerker, U. Drescher, H. Tanaka, Analysis of ephrin-A2 in the chick retinotectal projection using a function-blocking monoclonal antibody, Journal of Neurobiology, 10.1002/neu.1032, 47, 4, 245-254, 2001.06. |
| 45. | Hiroko Iwamasa, Kunimasa Ohta, Tomoko Yamada, Kazuo Ushijima, Hidenori Terasaki, Hideaki Tanaka, Expression of Eph receptor tyrosine kinases and their ligands in chick embryonic motor neurons and hindlimb muscles, Development Growth and Differentiation, 10.1046/j.1440-169X.1999.00468.x, 41, 6, 685-698, 1999.12. |
| 46. | Kunimasa Ohta, David Tannahill, Kanako Yoshida, Alan R. Johnson, Geoffrey M.W. Cook, Roger J. Keynes, Embryonic lens repels retinal ganglion cell axons, Developmental Biology, 10.1006/dbio.1999.9312, 211, 1, 124-132, 1999.07. |
| 47. | Katsumi Nagata, Naohiro Hori, Kenzo Sato, Kunimasa Ohta, Hideaki Tanaka, Yasutake Hiji, Cloning and functional expression of an SGLT-1-like protein from the Xenopus laevis intestine, American Journal of Physiology - Gastrointestinal and Liver Physiology, 276, 5 39-5, G1251-G1259, 1999.05. |
| 48. | Shigeki Hirano, Hideaki Tanaka, Kunimasa Ohta, Masao Norita, Kaeko Hoshino, Reiko Meguro, Masahiko Kase, Normal ontogenic observations on the expression of Eph receptor tyrosine kinase, Cek8, in chick embryos, Anatomy and Embryology, 10.1007/s004290050130, 197, 3, 187-197, 1998.03. |
| 49. | K Ohta, H Iwamasa, U Drescher, H Terasaki, H Tanaka, The inhibitory effect on neurite outgrowth of motoneurons exerted by the ligands ELF-1 and RAGS, MECHANISMS OF DEVELOPMENT, 10.1016/S0925-4773(97)00056-7, 64, 1-2, 127-135, 1997.06, Eph-related receptor tyrosine kinases and ligands are expressed at high levels in the developing nervous system, giving rise to the proposal that they are involved in neuronal connection. Cek8 was found to be predominantly expressed on a subset of motoneurons innervating limb but not body muscles during motoneuron axonal growth. Here we show that the ligands RAGS and ELF-1 were expressed in limb buds and that they activated Cek8 when presented in membrane-bound or clustered forms of Fe chimeric proteins but not in unclustered soluble forms. When chick embryonic motoneurons enriched by panning were cultured on clustered farms of RAGS-Fc and ELF-I-Fc, the neurite growth of motoneurons expressing Cek8 was inhibited. Our results show a relationship between receptor phosphorylation and neurite growth inhibition and suggest that Eph-related kinases and Ligands have a regulatory effect on the axon growth of motoneurons during development. (C) 1997 Elsevier Science Ireland Ltd.. |
| 50. | Bruno Monschau, Claus Kremoser, Kunimasa Ohta, Hideaki Tanaka, Tomomi Kaneko, Tomoko Yamada, Claudia Handwerker, Martin R. Hornberger, Jürgen Löschinger, Elena B. Pasquale, Doyle A. Siever, Michael F. Verderame, Bernhard K. Müller, Friedrich Bonhoeffer, Uwe Drescher, Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons, EMBO Journal, 10.1093/emboj/16.6.1258, 16, 6, 1258-1267, 1997.03. |
| 51. | Masaaki Nakamura, Kunimasa Ohta, Kaoru Hirokawa, Mikiko Fukushima, Makoto Uchino, Masayuki Ando, Hideaki Tanaka, Developmental and denervation changes in c-ret proto-oncogene expression in chick motoneurons, Molecular Brain Research, 10.1016/0169-328X(95)00347-U, 39, 1-2, 1-11, 1996.07. |
| 52. | Mikiko Fukushima, Masaaki Nakamura, Kunimasa Ohta, Ryouichi Okamura, Akira Negi, Hideaki Tanaka, Regional specification of motoneurons along the anterior-posterior axis is independent of the notochord, Development, 122, 3, 905-914, 1996.03. |
| 53. | Kunimasa Ohta, Masaaki Nakamura, Kaoru Hirokawa, Shigeyasu Tanaka, Atsushi Iwama, Toshio Suda, Masayuki Ando, Hideaki Tanaka, The receptor tyrosine kinase, Cek8, is transiently expressed on subtypes of motoneurons in the spinal cord during development, Mechanisms of Development, 10.1016/0925-4773(95)00461-0, 54, 1, 59-69, 1996.01. |
| 54. | Kunimasa Ohta, Akihito Mizutani, Atsushi Kawakami, Yasunori Murakami, Yasuyo Kasuya, Shin Takagi, Hideaki Tanaka, Hajime Fujisawa, Plexin A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions, Neuron, 10.1016/0896-6273(95)90266-X, 14, 6, 1189-1199, 1995.06. |
| 55. | M. Satoda, S. Takagi, K. Ohta, T. Hirata, H. Fujisawa, Differential expression of two cell surface proteins, neuropilin and plexin, in Xenopus olfactory axon subclasses, Journal of Neuroscience, 15, 1 II, 942-955, 1995.01. |
| 56. | Kunimasa Ohta, Kazumitsu Hanai, Hiromichi Morita, Glutathione-binding proteins identified by monoclonal antibodies which depress the behavioral response evoked by glutathione in Hydra, BBA - General Subjects, 10.1016/0304-4165(92)90071-2, 1117, 2, 136-142, 1992.09. |
| 57. | Kunimasa Ohta, Shin Takagi, Hiroaki Asou, Hajime Fujisawa, Involvement of neuronal cell surface molecule B2 in the formation of retinal plexiform layers, Neuron, 10.1016/0896-6273(92)90230-B, 9, 1, 151-161, 1992.07. |
| 58. | Masahiko Sakaguchi, Kazumitsu Hanai, Kunimasa Ohta, Masaaki Kitajima, Sachiko Matsuhashi, Katsuji Hori, Hiromichi Morita, Monoclonal antibodies that depress a specific subset of multiple components of the glutathione-induced response of Hydra, Journal of Comparative Physiology A, 10.1007/BF00199601, 168, 4, 409-416, 1991.04. |
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