Kyushu University Academic Staff Educational and Research Activities Database
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Kenji Hamase Last modified date:2021.04.09

Graduate School
Undergraduate School

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 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Country of degree conferring institution (Overseas)
Field of Specialization
Drug Discovery and Evolution
Total Priod of education and research career in the foreign country
Research Interests
  • Chiral amino acid metabolomics studies and clinical applications
    keyword : Chiral amino acids, Clinical metabolomics
  • Determination of D-amino acids in mammals and the study of their functions
    keyword : D-amino acids
  • Sensitive determination of hormones
    keyword : Sensitive determination
  • Development of novel functional reagents
    keyword : functional reagents
Academic Activities
1. Akiko MORIKAWA, Kenji HAMASE, Tomohiro OHGUSU, Sachise ETOH, Hiroyuki TANAKA, Ichiro KOSHIISHI, Yukihiro SHOYAMA and Kiyoshi ZAITSU, Immunohistochemical localization of D-alanine to β-cells in rat pancreas, Biochemical and Biophysical Research Communications, 355, 872-876, 2007.04.
2. Kenji HAMASE, Akiko MORIKAWA, Tomohiro OHGUSU, Wolfgang LINDNER and Kiyoshi ZAITSU, Comprehensive analysis of branched aliphatic D-amino acids in mammals using an integrated multi-loop two-dimensional column-switching high-performance liquid chromatographic system combining reversed-phase and enantioselective columns, Journal of Chromatography A, 1143, 105-111, 2007.03.
3. Kenji HAMASE, Sayaka TAKAGI, Akiko MORIKAWA, Ryuichi KONNO, Akira NIWA, and Kiyoshi ZAITSU, Presence and origin of large amounts of D-proline in the urine of mutant mice lacking D-amino acid oxidase activity, Analytical and Bioanalytical Chemistry, 386, 705-711, 2006.10.
4. Junzo HIRANO, Kenji HAMASE, Hiroko FUKUDA, Tatsunosuke TOMITA and Kiyoshi ZAITSU, Novel stable fluorophore, 6-methoxy-4-quinolone, with strong fluorescence in wide pH range of aqueous media, and its application as a fluorescent labeling reagent, Journal of Chromatography A, 10.1016/j.chroma.2004.10.020, 1059, 1-2, 225-231, 1059, 225-231, 2004.12.
5. Kenji HAMASE, Junzo HIRANO, Yuki KOSAI, Tatsunosuke TOMITA and Kiyoshi ZAITSU, A Sensitive Internal Standard Method for the Determination of Melatonin in Mammals using Precolumn Oxidation Reversed-Phase High-Performance Liquid Chromatography, Journal of Chromatography B, 10.1016/j.jchromb.2004.08.027, 811, 2, 237-241, 811, 237-241, 2004.11.
6. Hua ZHAO, Kenji HAMASE, Akiko MORIKAWA, Zongyin Qiu and Kiyoshi ZAITSU, Determination of D- and L-Enantiomers of Threonine and allo-Threonine in Mammals using Two-Step High-Performance Liquid Chromatography, Journal of Chromatography B, 10.1016/j.jchromb.2004.08.006, 810, 2, 245-250, 810, 245-250, 2004.10.
7. Junzo HIRANO, Kenji HAMASE, Takeyuki AKITA and Kiyoshi ZAITSU, Crystal Structure of N-[(6-Methoxy-4-oxo-1,4-dihydroquinolin-3-yl)methyl]-2,2-dimethylpropanamide, Analytical Sciences, 20, x115-x116, 2004.09.
8. Koji YAMAMOTO, Kenji HAMASE and Kiyoshi ZAITSU, 2-Amino-3-phenylpyrazine, a Sensitive Fluorescence Prelabeling Reagent for the Chromatographic or Electrophoretic Determination of Saccharides, Journal of Chromatography A, 10.1016/S0021-9673(03)00452-7, 1004, 1-2, 99-106, 1004, 99-106, 2003.07.
9. Tatsunosuke TOMITA, Kenji HAMASE, Hiromi HAYASHI, Hiroko FUKUDA, Junzo HIRANO and Kiyoshi ZAITSU, Determination of Endogenous Melatonin in the Individual Pineal Glands of Inbred Mice using Precolumn Oxidation Reversed-Phase Micro-High-Performance Liquid Chromatography, Analytical Biochemistry, 10.1016/S0003-2697(03)00079-4, 316, 2, 154-161, 316, 154-161, 2003.05.
10. Akiko MORIKAWA, Kenji HAMASE and Kiyoshi ZAITSU, Determination of D-Alanine in the Rat Central Nervous System and Periphery using Column-Switching High-Performance Liquid Chromatography, Analytical Biochemistry, 10.1016/S0003-2697(02)00432-3, 312, 1, 66-72, 312, 66-72, 2003.01.
11. Kenji HAMASE, Tomomi INOUE, Akiko MORIKAWA, Ryuichi KONNO and Kiyoshi ZAITSU, Determination of Free D-Proline and D-Leucine in the Brains of Mutant Mice Lacking D-Amino-Acid Oxidase Activity, Analytical Biochemistry, 10.1006/abio.2001.5382, 298, 2, 253-258, 298, 253-258, 2001.11.
12. Tomomi INOUE, Kenji HAMASE, Akiko MORIKAWA and Kiyoshi ZAITSU, Determination of Minute Amounts of D-Leucine in Various Brain Regions of Rat and Mouse Using Column-Switching High-Performance Liquid Chromatography, Journal of Chromatography B, 10.1016/S0378-4347(00)00244-9, 744, 1, 213-219, 744, 213-219, 2000.07.
13. Kenji HAMASE, Tatsunosuke TOMITA, Ayako KIYOMIZU and Kiyoshi ZAITSU, Determination of Pineal Melatonin by Precolumn Derivatization Reversed-Phase High Performance Liquid Chromatography and Its Application to the Study of Circadian Rhythm in Rats and Mice, Analytical Biochemistry, 10.1006/abio.1999.4435, 279, 1, 106-110, 279, 106-110, 2000.01.
Membership in Academic Society
  • Japan Society of Clinical Chemistry