| 1. |
中尾実樹, 新版 魚病学概論, 恒星社厚生閣, 第２章 魚類の生体防御と耐病性育種, 2020.09. |
| 2. |
中尾実樹, 動物学の百科事典「補体の進化」, 丸善, 2018.09. |
| 3. |
Miki Nakao, Tomonori Somamoto, The evolution of complement system functions and pathways in vertebrates. in THE EVOLUTION OF THE IMMUNE SYSTEM: A BALANCE BETWEEN CONSERVATION AND DIVERSITY, Elsevier, in press, 2015.08, An ancestral complement system is considered to be an opsonic system that seems a combination of the lectin and alternative pathways known in mammalian complement. The ancestral system equipped with lectin-like pattern-recognition molecule linked with specific proteases homologous to MASP and factor B, which cleave C3 into physiologically active forms with inflammatory and opsonic functions, as seen in primitive invertebrate species. In vertebrates, two rounds of whole-genome duplication have generated two additional reaction cascades, the classical and lytic pathway, providing jawed vertebrates with much more specific and efficient ability of pathogen elimination. A trace of molecular and functional evidence that represent a transient status from invertebrate prototypic complement to full equipped system can be found in extant jawless species such as lamprey. A striking diversity of complement component isoforms unique to teleost fish is also discussed in a functional context.. |
| 4. |
中尾実樹、杣本智軌, 補体への招待 2-5-2. 補体系の進化：脊椎動物, メジカルビュー, 2011.04.  |
| 5. |
Nakao M, Mutsuro J, Yano T, Expansion of the genes encoding complement components in bony fish. In "Recent Research Developments in Immunology" ed. by S. G. Pandalai, Reseach Signpost, Kerala, India., Vol. 3, Part I" . pp 15-32,, 2001.01. |
| 6. |
中尾実樹・矢野友紀, cDNAサブトラクションを利用したコイ生体防御関連遺伝子の同定 , 「魚類の免疫系」(水産学シリーズ）, 渡辺 翼編, 恒星社厚生閣, pp 128-139., 2003.01. |
| 7. |
矢野友紀・中尾実樹, 硬骨魚類の補体の特性, 「魚類の免疫系」(水産学シリーズ）, 渡辺 翼編, 恒星社厚生閣, pp 51-61., 2003.01. |
