| 1. |
Tasutake Tanaka, Michio Kawano, Makoto Asahina, Katsumi Imaizumi, Masao Sato, Smek2 is a multi-function regulator of three major nutritions, 22nd-IUNS International Congress of Nutrition, 2022.12. |
| 2. |
Zhe Jiang, Takuya Hayashi, Kentaro Kashima, Kayo Kurotani, Bungo Shirouchi, Tetsuya Mizoue, Masao Sato, High Serum Phospholipid Dihomo-γ-Linolenic Acid Level is Associated with NAFLD in the Japanese Population: A Cross-sectional Study, IcoFF2019, 2019.12. |
| 3. |
Masao Sato, The healthy and nutritional properties of eggs –Promoting better & happier life–, IcoFF2019, 2019.12. |
| 4. |
Yurika Miyazaki, Masahiro Ono, Ai Sawazaki, Yoshinori Katakura, Bungo Shirouchi, Masao Sato, Lipid extract of rice bran changes the neural morphology in human neuroblastoma cell line SH-SY5Y, The 3rd International Symposium on Rice Science in Global Health, 2018.11. |
| 5. |
Misato Niibo, Bungo Shirouchi, Masao Sato, Development of hepatic disease model mice by inducing inflammation, AFELiSA (International Symposium on Agriculture, Food, Environmental and Life Science in Asia) 2017, 2017.11. |
| 6. |
Motonori Miyago, Yurika Miyazaki, Masahiro Ono, Bungo Shirouchi, Masao Sato, Cerebral cortical oxycholesterols as indices for dementia in the rats, AFELiSA (International Symposium on Agriculture, Food, Environmental and Life Science in Asia) 2017, 2017.11. |
| 7. |
Ai Sawazaki, Yoshinori Katakura, Bungo Shirouchi, and Masao Sato, Neural morphometric appraisal by addition of apolipoprotein E in human neuroblastoma cell line SH-SY5T, AFELiSA (International Symposium on Agriculture, Food, Environmental and Life Science in Asia) 2017, 2017.11. |
| 8. |
Asami Teramoto, Bungo Shirouchi, Masao Sato, Effects of dietary phosphatidylserine on gastric emptying and postprandial glycemic response in rats, AFELiSA (International Symposium on Agriculture, Food, Environmental and Life Science in Asia) 2017, 2017.11. |
| 9. |
Takuya Mizokami, Yasutake Tanaka, Bungo Shirouchi, Satoshi Ishizuka, Taizou Nagura, Michihiro Fukushima, Masao Sato, Effects of dietary trimethylglycine on cholesterol metabolism, AFELiSA (International Symposium on Agriculture, Food, Environmental and Life Science in Asia) 2017, 2017.11. |
| 10. |
MASAO SATO, Mitsukazu Sakata, Mari Seno, Hiroaki Matsusaka, Kiyomi Takahashi, Yuki Nakamura, Yoshiyuki Yamagata, Enrique R. Angeles, T Mochizuki, T. Kumamaru, Akiko Enomoto, KOSUKE TASHIRO, Satoru Kuhara, Hikaru Satoh, Atsushi Yoshimura, Mutation Breeding of rice giant embryo toward A high oil content cultivar
, The 3rd International Conference on Rice Bran Oil, 2016.10, Objectives: Rice bran oil is a byproduct of the milling of rice (Oryza sativa L.). It offers various health benefits and has a beneficial fatty acid composition. To increase the amount of rice bran as a sink for triacylglycerol (TAG), we developed and characterized new breeding materials with giant embryos originated from a high-yielding cultivar ‘Mizuhochikara’.
Strategy and Methods: The high-yielding cultivar ‘Mizuhochikara’ grown for rice bread and animal feed in southwestern Japan was used as the genetic background. To induce mutants, we treated fertilized egg cells of ‘Mizuhochikara’ with N-methyl-N-nitrosourea (MNU). We dehulled M2 seeds from 5,645 M1 plants and screened them by eye for giant embryo mutants. Mutant lines were backcrossed to ‘Mizuhochikara’ to remove undesirable traits, and we selected the promising line. To evaluate whether the mutant line retained the superior agronomic traits of ‘Mizuhochikara’, we evaluated 11 agronomic traits of F3 generation: plant height, culm length, panicle length, number of panicles per plant, number of grains per panicle, fertility, panicle weight per plant, yield per plant, seed length, seed width and seed thickness. We also compared the TAG contents of rice bran in the mutant line with those of ‘Mizuhochikara’. To reveal the underlying genetic mechanisms, we performed allelic testing and sequence analysis. For allelic testing, the giant embryo mutant EM40, which carries giant embryo (ge), was used as a tester line. For sequence analysis, Os07g0603700, which was causal gene of ge on chromosome 7, was sequenced.
Results: By screening M2 seeds, we isolated four giant embryo mutant lines: MGE8, MGE12, MGE13 and MGE14. After growing backcrossed progenies, we selected MGE13 as a promising line based on embryo size and similarity to ‘Mizuhochikara’. As a result of evaluation of agronomic traits, MGE13 was not significantly different except in having a longer culm than ‘Mizuhochikara’. The TAG contents of rice bran in 50 seeds of MGE13 increased by 142% compared to ‘Mizuhochikara’. Genetic analysis revealed that the causative locus in line MGE13 was allelic to ge, and had base changes in the causal gene Os07g0603700. Further selection of plants, the production of breeding seeds, yield tests and characterization of oil quality are required for the development of the new cultivar.
Conclusions: We developed the new giant embryo mutant line MGE13. This line showed almost the same yield performances and increased the TAG contents by about 1.4 times, compared to ‘Mizuhochikara’. MGE13 would be useful for breeding of a high oil content cultivar.
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| 11. |
MASAO SATO, Physiological significance of oxidized cholesterols, ACN2015, a joint meeting with The 69th Annual Meeting of Japan Society of Nutrition and Food science, 2015.05. |
| 12. |
Bungo Shirouchi, Asuka Kawauti, Yumiko Furukawa, Yuko Arima, MASAO SATO, Effects of dietary phosphatidylcholine on postprandial lymphatic inflammatory cytokine levels in rats, ACN2015, a joint meeting with The 69th Annual Meeting of Japan Society of Nutrition and Food science, 2015.05. |
| 13. |
Yasutake Tanaka, Kiyomi Takahashi, Taiki Akasaka, Naoko Fujita, Yuhi Saito, Bungo Shirouchi, MASAO SATO, Screening of rice (Oryza sativa L.) grains with antidiabetic functionalities, ACN2015, a joint meeting with The 69th Annual Meeting of Japan Society of Nutrition and Food science, 2015.05. |
| 14. |
Bungo Shirouchi, Asuka Kawauchi, Takuya Kato, Yumiko Furukawa, Yuko Arima, MASAO SATO, Dietary phosphatidylcholine reduces lymphatic inflammatory cytokine levels in thoracic lymph-duct cannulated rats, 1st Asian Conference on Oleo Science (ACOS2014), 2014.09. |
| 15. |
Bungo Shirouchi, Ryuei Baba, Takuya Kato, Nagao K, MASAO SATO, Dietary Resveratrol Alleviates Atherosclerotic Lesions in ApoE-deficient Mice: Comparison with Pterostilbene, a Resveratrol Analog, 27th International Conference on Polyphenols & 8th Tannin Conference, 2014.09. |
| 16. |
Bungo Shirouchi, MASAO SATO, Lymphatic Lipid Transport Regulated by Dietary Components and Drug, 105th AOCS Annual Meeting & Expo, A Joint World Congress with the Japan Oil Chemists' Society, 2014.05. |
| 17. |
Development and evaluation of giant embryo mutants originated from rice variety "Mizuhochikara". |
| 18. |
MASAO SATO, Morita Y, Ogawa A, Kadooka Y., Bungo Shirouchi, Effects of Dietary Lactobacillus gasseri SBT2055 on Glucose Metabolism in Rats, IUNS 20th International Congress of Nutrition, 2013.09. |
| 19. |
Bungo Shirouchi, Nakamura Y, MASAO SATO, Furukawa Y, Kawauchi A, katsumi imaizumi, DIETARY LIPID DYNAMICS IN THE THORACIC LYMPH REGULATED BY FOOD COMPONENTS AND DRUG IN THE INTESTINAL LUMEN, IUNS 20th International Congress of Nutrition, 2013.09. |
| 20. |
Tanaka Y, Nagao K, Nakagiri H, Nagaso T, Iwasa Y, Mori H, Asahina M, katsumi imaizumi, MASAO SATO, Increase of Serum Cholesterol Level Induced by Dietary Cholesterol Involves Secretion of Triacylglycerol from Liver in EXHC Rats, IUNS 20th International Congress of Nutrition, 2013.09. |
| 21. |
Ngoc Minh Pham, Akiko Nanri, Kazuki Yasuda, Kayo Kurotani, Keisuke Kuwahara, MASAO SATO, Hitomi Hayabuchi, Tetsuya Mizoue, Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population, The 8th Asia Pacific Conference on Clinical Nutrition (APCCN 2013),, 2013.06, Objective: Coffee and green tea consumption has been suggested to protect against cancer, in which adipose-derived hormones (adipokines) are thought to be involved. However, few studies have investigated the association between consumption of these beverages and adipokines, and their results are inconsistent. We examined the association of coffee, green tea and caffeine consumption with serum adipokines in a Japanese working population.
Methods: The authors analyzed data (n = 509) from a cross-sectional survey among Japanese workers aged 20-68 years. Serum concentrations of adiponectin, leptin, resistin, visfatin, plasminogen activator inhibitor 1 (PAI-1) and adipsin were measured using Bio-Plex Pro Human Diabetes Assay kit on Bio-Plex 3D system. Coffee and green tea consumption was assessed by a validated diet history questionnaire, and caffeine intake from these sources was estimated. Multiple regression analysis was performed with adjustment for potential confounding variables.
Results: Coffee consumption was significantly inversely associated with serum leptin and PAI-1 (P for trend = 0.004 and 0.02, respectively). Similar associations were observed for caffeine intake (P for trend = 0.01 and 0.02, respectively). Moreover, there was a suggestion of positive association between coffee consumption and serum resistin in current male smokers (P for trend = 0.01), but not in male non-smokers (P for trend = 0.35, P for interaction = 0.38). Further, a significant positive association between coffee consumption and serum adiponectin appeared to be confined to men (P for trend = 0.046, P for interaction = 0.46). Green tea consumption was not associated with any adipokine.
Conclusions: Higher consumption of coffee and caffeine was associated with lower serum leptin and PAI-1 in Japanese adults.
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| 22. |
Shimabukuro M, 大川知奈美, SATO MASAO, Higashida M, Sato H, Kurobe H, Takao S, Hirata Y, Nakayama T, Lei XF, Kim-Kaneyama JR, Fukuda D, Yamada H, Kitagawa T, Sata M, Effects of Ezetimibe on Oxidized Cholesterol and Fatty-acid Components in Epicardial fat and Myocardium: A Gas Chromatography-Mass Spectrometry Analysis, 第77回日本循環器学会学術集会, 2013.03, Background: Growing evidence suggest that epicardial adipose tissue (EAT) may contribute to the development of coronary artery disease (CAD). Proinflammatory cytokines/adipocytokines are expressed and secreted at a higher level in EAT of individuals with coronary artery disease (CAD) (Hirata et al, JACC 2011). Oxidized cholesterol and fatty acids in food serve as strong atherogenic components, but their distribution in EAT remain unclarified. Objective: We determined effects of ezetimibe on oxidized cholesterol and fatty-acid components in EAT and myocardium using gas chromatography-mass spectrometry analysis.Methods: Male guinea mini pigs were divided into 3 groups of control (80 kcal/kg/day), 1.5% cholesterol-containing high-fat diet (120 kcal/kg/day) (HFD), and HFD+
ezetimibe (0.3mg/kg/day) (Ezetimibe). Fourteen oxidized cholesterol and twenty fatty-acid components were measured by a gas chromatography-mass spectrometry analysis. Results: 1. Plasma levels of Α- and Β-epoxy-cholesterol were increased and 7-ketocholesterol was decreased in HFD group;Α- and Β-epoxy-cholesterol in EAT were decreased in HFD group;Α-epoxy-cholesterol in plasma and epicardial fat were decreased in Ezetimibe group as compared to HFD group, 2. Levels of arachidonic acids were increased comparably in HFD and Ezetimibe groups, 3. EAT volume and echocardiographic indices were comparable among three groups. Conclusion: Components of atherogenic oxidized cholesterol and fatty acids are altered in plasma and perivascular fat and ezetimibe ma
y be beneficial in regulating these components.. |
| 23. |
Dietary guar gum reduces lymph flow and diminishes lipid transport in thoracic duct-cannulated rats.. |
| 24. |
Effects of Lactobacillus gasseri SBT2055 on glucose metabolism in diabetic rats. |
| 25. |
Positional identification of a gene that regulates serum HDL cholesterol and apolipoprrotein A-I in rats and mice. |
| 26. |
Atherosclerosis protected by foods -beyond cholesterol-According to a meta-analysis of the reports in Apo E -/- mice-. |
| 27. |
Effect od dietary sphingomyelin on protein kinase C and phosphlipid composition in the brain of senescence-accelerated mice. |
| 28. |
The relationship between hypercholesterolemia and the promoter region of fatty acid syntase gene in exogenously hypercholesterolemic rat. |
