| 1. |
河崎雅弘,荻野洋一郎,諸井亮司,鮎川保則
, 下顎顎義歯装着患者の咀嚼機能に影響を与える因子についての検証, 日本顎顔面補綴学会 第40回総会学術大会, 2023.06. |
| 2. |
和智貴紀, 諸井 亮司, 的野 良就, 古藤航, 北村和幸, 牧平 清超, 前歯部歯肉退縮による審美障害に対して熱可塑性材料を用いて暫間対応した１症例, 日本補綴歯科学会 平成２７年度九州支部学術大会, 2015.08. |
| 3. |
首藤 崇裕, 和智 貴紀, 片山 洋子, 篠原 義憲, 的野 良就, 諸井 亮司, 牧平 清超, ラット実験モデルを用いたインプラント周囲粘膜炎の解析, 日本補綴歯科学会 第１２３回学術大会, 2014.05. |
| 4. |
和智 貴紀, 首藤 崇裕, 中村 優介, 的野 良就, 篠原 義憲, 諸井 亮司, 牧平 清超, インプラント体表面からの溶出チタンの検討, 日本補綴歯科学会 第１２３回学術大会, 2014.05. |
| 5. |
Takahiro Shuto, Takanori Wachi, Yuichi Mine, Ryoji Moroi, Yoshinari Matono, Hiroki Nikawa, Yoshihiro TERADA, Seicho Makihira, RANKL Expression in the Tissues around Implant Injected with LPS, IADR-APR, 2013.08, Abstract
Objectives: It was reported that activated T cells in periodontal diseased gingival tissues expressed RANKL. Hence we investigated whether T cells in the tissues suffered from peri-implantitis could express RANKL or not.
Methods: Mini pure titanium implants (mini-implant) were placed into palatine bone of Wistar rats, followed by that lipopolysaccharide derived from Porphyromonas gingivalis (P.g.-LPS) was intermittently injected into the gingival tissues around mini-implant. Inflamed tissues by P.g.-LPS (P.g.-LPS samples) were collected from around mini-implant. The mRNA expression patterns of RANKL and OPG in the tissues, which were known as the markers of bone resorption, were examined by real-time RT-PCR. In addition, Immunohistochemical analysis was performed for comparative investigation of T cells expressing RANKL by using anti-CD3 and anti-RANKL antibodies. The tissues without P.g.-LPS were used as the control samples.
Results: P.g.-LPS enhanced the mRNA expressions of RANKL in the tissues around mini-implant, as compared with those of control samples without P.g.-LPS. On the other hand, the mRNA expressions of OPG in the P.g.-LPS samples were decreased. CD3- or RANKL-positive cells were observed in each tissue sample. However, only in the P.g.-LPS samples, the cells stained with both anti-CD3 and anti-RANKL antibodies were detected.
Conclusions: These data, taken together, revealed that P.g.-LPS injection enhanced the mRNA expressions of RANKL in the tissues around mini-implant of the rat model. Additionally, the CD3-positive cells in the tissues around mini-implant injected with P.g.-LPS expressed the RANKL molecules. Therefore, it is suggested that the activated T cells in the tissues suffered from peri-implantitis may be the primary sources of RANKL, similar to the case for periodontitis, and be involved in the bone resorption associated with peri-implantitis.. |
| 6. |
諸井 亮司, 牧平 清超, 和智貴紀, 寺田 善博, 光触媒材料を含有した粘膜調整材の抗菌・抗真菌効果, 日本老年歯科医学会, 2013.06. |
| 7. |
諸井亮司，内丸雅之，坂井貴子，出口幹人 *，寺田善博（九州大，* ㈱松風）, 光触媒材料含有粘膜調整材の抗菌・抗真菌効果の持続性, 社団法人日本補綴歯科学会第１２０回記念学術大会, 2011.05. |
| 8. |
○岡崎昌太，牧平清超 *，峯 裕一，首藤崇裕 *，諸井亮司 *，寺田善博 *，二川浩樹（広島大，* 九州大）, メカニカルストレスに対する破骨細胞の反応にカルシウムの流入が関与している
, 社団法人日本補綴歯科学会第１２０回記念学術大会, 2011.05. |
| 9. |
内丸雅之，坂井貴子，諸井亮司，吉田創介，寺田善博, 光触媒含有ティッシュコンディショナーの抗菌・抗真菌効果について, 平成２１年度日本歯科理工学会九州支部夏期セミナー, 2009.08. |
| 10. |
内丸雅之、坂井貴子、諸井亮司、吉田創介、出口幹人、寺田善博, 光触媒材料含有粘膜調整材の抗菌・抗真菌効果, 日本補綴歯科学会第118回学術大会, 2009.06. |
| 11. |
程 亜麗，谷口久美子，坂井貴子，諸井亮司，寺田善博, 光触媒材料含有義歯床用レジンの汚れ分解能と機械的性質の経時的変化, 第115回日本補綴歯科学会学術大会, 2006.07. |
| 12. |
首藤真一，諸井亮司，程亜麗，内丸雅之，坂井貴子，寺田善博, 義歯床用レジンへの二酸化チタン光触媒の応用—歯肉由来培養細胞への影響について—, 第114回日本補綴歯科学会学術大会, 2005.10. |
