複数b値の拡散強調像の新しいモデル解析
キーワード:拡散強調画像、統計学的モデル
2019.04~2021.04.
筑井 徹(ちくい とおる) | データ更新日:2024.04.16 |
主な研究テーマ
頭頸部のMRI造影剤分布の解析
キーワード:MRI造影剤、頭頸部
2006.03~2016.04.
キーワード:MRI造影剤、頭頸部
2006.03~2016.04.
咀嚼筋のMRI
キーワード:MRI, 拡散、ADC, トラクトグラフィー
2009.04~2012.03.
キーワード:MRI, 拡散、ADC, トラクトグラフィー
2009.04~2012.03.
MRIによる頭頸部臓器ののT1,T2,ADC 算出, 拡散パラメーターの推定
キーワード:MRI, T1値、T2値、ADC
2006.04.
キーワード:MRI, T1値、T2値、ADC
2006.04.
頸部リンパ節の早期検出
キーワード:頸部リンパ節、画像診断
1998.04~2003.12.
キーワード:頸部リンパ節、画像診断
1998.04~2003.12.
研究業績
主要原著論文
1. | Toru Chikui, Masahiro Ohga, Yukiko Kami, Osamu Togao, Shintaro Kawano, Tamotsu Kiyoshima and Kazunori Yoshiura, Correlation between diffusion-weighted image-derived parameters and dynamic contrast-enhanced magnetic resonance imaging-derived parameters in the orofacial region, Acta Radiologica Open, 10.1177/20584601241244777, 13, (3), 1-9, 2024.03, Background: Diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) are widely used in the orofacial region. Furthermore, quantitative analyses have proven useful. However, a few reports have described the correlation between DWI-derived parameters and DCE-MRI-derived parameters, and the results have beencontroversial. Purpose: To evaluate the correlation among parameters obtained by DWI and DCE-MRI and to compare them between benign and malignant lesions. Material and Methods: Fifty orofacial lesions were analysed. The apparent diffusion coefficient (ADC), true diffusion coefficient (D), pseudodiffusion coefficient (D*) and perfusion fraction (f) were estimated by DWI. For DCE-MRI, TK model analysis was performed to estimate physiological parameters, for example, the influx forward volume transfer constant into the extracellular-extravascular space (EES) (Ktrans) and fractional volumes of EES and plasma components (ve and vp). Results: Both ADC and D showed a moderate positive correlation with ve (ρ = 0.640 and 0.645, respectively). Ktrans showed a marginally weak correlation with f (ρ = 0.296), while vp was not correlated with f or D*; therefore, IVIM perfusion-related parameters and TK model perfusion-related parameters were not straightforward. Both D and ve yielded high diagnostic power between benign lesions and malignant tumours with areas under the curve (AUCs) of 0.830 and 0.782, respectively. Conclusion: Both D and ve were reliable parameters that were useful for the differential diagnosis. In addition, the true diffusion coefficient (D) was affected by the fractional volume of EES.. |
2. | Kam Yukiko, Chikui Toru, Togao Osamu, Kawano Shintaro, Fujii Shinsuked, Ooga, Masahiro, KiyoshimaTamotsu, Yoshiura Kazunori, Usefulness of reconstructed images of Gd-enhanced 3D gradient echo sequences with compressed sensing for mandibular cancer diagnosis: comparison with CT images and histopathological findings, European Radiology , https://doi.org/10.1007/s00330-022-09075-w, 2022.08, Objectives To compare the delineation of mandibular cancer by 3D T1 turbo field echo with compressed SENSE (CS-3D-T1TFE) images and MDCT images, and to compare both sets of images with histopathological findings, as the gold standard, to validate the accuracy and clinical usefulness of CS-3D-T1TFE reconstruction. Methods Twenty-four patients with mandibular squamous cell carcinoma (SCC) who underwent MRI including CS-3D-T1TFE and MDCT examinations before surgery were retrospectively included. For both examinations, 0.5-mm-thick coronal plane images and 0.5-mm-thick plane images perpendicular and parallel to the dentition were constructed. Two radiologists rated bone invasion in three categories indexed by cortical bone, cancellous bone, and mandibular canal (MC), and inter-rater agreement was assessed by weighted kappa statistics. In 20 of the 24 patients who underwent surgery, the correlation of bone invasion with the histopathological evaluation by pathologists was assessed using Pearson’s correlation coefficient. Soft-tissue invasion was assessed by diagnosing the presence of invasion into the mylohyoid muscle, gingivobuccal fold, and masticator space, and inter-rater agreement was assessed by kappa statistics. Results The interobserver agreement for bone invasion assessment was almost perfect with CS-3D-T1TFE and substantial with MDCT. The image evaluations by both observers agreed with the pathological evaluations in 15 of the 20 cases, showing high correlation (r > 0.8). CS-3D-T1TFE also showed higher inter-rater agreement than MDCT for all measures of soft-tissue invasion. Conclusions CS-3D-T1TFE reconstructed images were clinically useful in accurately depicting the extent of mandibular cancer invasion and potentially solving the problem of lesion overestimation associated with conventional MRI. |
3. | Naoki Kaneko, Junsei Sameshima, Shintaro Kawano, Toru Chikui, Takeshi Mitsuyasu, Hu Chen, Taiki Sakamoto, SeijiNakamura, Comparison of computed tomography findings between odontogenic keratocyst and ameloblastoma in the mandible: Criteria for differential diagnosis, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 10.1016/j.ajoms.2022.07.016, 2022.09, Objectives Appropriate differential diagnosis between odontogenic keratocysts (OKCs) and ameloblastomas before treatment is crucial, but the radiographic findings, including computed tomography (CT), are often similar. This study, therefore, aimed to compare the CT findings of OKCs and ameloblastomas in the mandible. Methods Forty-one OKC and 28 ameloblastoma patients were radiologically evaluated by using initial CT images focusing on features such as long/short diameters, CT values, the appearance of the cortex, locularity, scalloped margins, sclerotic rims, and high-density structures. Subtypes of ameloblastoma were also considered. Statistical analyses, including multivariate logistic regression analysis, were performed to determine the features that were helpful for differential diagnosis. Results Short diameters and locularity were found to be significant features in the differential diagnosis. Between unicystic and conventional ameloblastomas, the frequency of sclerotic rims and buccal disappearance was significantly different. Based on these results, criteria were established for differential diagnosis between OKCs and ameloblastomas, and the diagnostic accuracy was 92.8 %. Conclusion This finding indicates that several CT findings are strikingly different between OKCs and ameloblastomas, and that these criteria for differential diagnosis are clinically useful.. |
4. | Takase H, Togao O, Kikuchi K, Hata N, Hatae R, Chikui T, Tokumori K, Kami Y, Kuga D, Sangatsuda Y, Mizoguchi M, Hiwatashi A, Ishigami K., Gamma distribution model of diffusion MRI for evaluating the isocitrate dehydrogenase mutation status of glioblastomas, Br J Radiol, DOI: 10.1259/bjr.20210392, 95, 2022 Feb 9:20210392. doi: 10.1259/bjr.20210392. Online ahead of print., 2022.02, Objective:To determine whether the γ distribution (GD) model of diffusion MRI is useful in the evaluation of the isocitrate dehydrogenase (IDH) mutation status of glioblastomas. Methods:12 patients with IDH-mutant glioblastomas and 54 patients with IDH-wildtype glioblastomas were imaged with diffusion-weighted imaging using 13 b-values from 0 to 1000 s/mm2. The shape parameter (κ) and scale parameter (θ) were obtained with the GD model. Fractions of three different areas under the probability density function curve (f1, f2, f3) were defined as follows: f1, diffusion coefficient (D) 1.0×10−3 and 3.0 × 10−3 mm2/s. The GD model-derived parameters measured in gadolinium-enhancing lesions were compared between the IDH-mutant and IDH-wildtype groups. Receiver operating curve analyses were performed to assess the parameters' diagnostic performances. Results:The IDH-mutant group’s f1 (0.474 ± 0.143) was significantly larger than the IDH-wildtype group’s (0.347 ± 0.122, p = 0.0024). The IDH-mutant group’s f2 (0.417 ± 0.131) was significantly smaller than the IDH-wildtype group’s (0.504 ± 0.126, p = 0.036). The IDH-mutant group’s f3 (0.109 ± 0.060) was significantly smaller than the IDH-wildtype group’s (0.149 ± 0.063, p = 0.0466). The f1 showed the best diagnostic performance among the GD model-derived parameters with the area under the curve value of 0.753. Conclusion:The GD model could well describe the pathological features of IDH-mutant and IDH-wildtype glioblastomas, and was useful in the differentiation of these tumors. Advances in knowledge:Diffusion MRI based on the γ distribution model could well describe the pathological features of IDH-mutant and IDH-wildtype glioblastomas, and its use enabled the significant differentiation of these tumors. The γ distribution model may contribute to the non-invasive identification of the IDH mutation status based on histological viewpoint.. |
5. | Togao O, Chikui T, Tokumori K, Kami Y, Kikuchi K, Momosaka D, Kikuchi Y, Kuga D, Hata N, Mizoguchi M, Iihara K, Hiwatashi A., Gamma distribution model of diffusion MRI for the differentiation of primary central nerve system lymphomas and glioblastomas, PLoS One, doi: 10.1371/journal.pone.0243839. eCollection 2020., 15, 12, e0243839., 2020.12, [URL], The preoperative imaging-based differentiation of primary central nervous system lympho- mas (PCNSLs) and glioblastomas (GBs) is of high importance since the therapeutic strate- gies differ substantially between these tumors. In this study, we investigate whether the gamma distribution (GD) model is useful in this differentiation of PNCSLs and GBs. Twenty- seven patients with PCNSLs and 57 patients with GBs were imaged with diffusion-weighted imaging using 13 b-values ranging from 0 to 1000 sec/mm2. The shape parameter (κ) and scale parameter (θ) were obtained with the GD model. Fractions of three different areas under the probability density function curve (f1, f2, f3) were defined as follows: f1, diffusion coefficient (D) 1.0×10−3 and 3.0 × 10−3 mm2/sec. The GD model-derived parameters were compared between PCNSLs and GBs. Receiver operating characteristic (ROC) curve analyses were performed to assess diagnostic performance. The correlations with intravoxel incoherent motion (IVIM)-derived parameters were evaluated. The PCNSL group’s κ (2.26 ± 1.00) was significantly smaller than the GB group’s (3.62 ± 2.01, p = 0.0004). The PCNSL group’s f1 (0.542 ± 0.107) was significantly larger than the GB group’s (0.348 ± 0.132, p |
6. | Chikui T, Tokumori K, Panyarak W, Togao O, Yamashita Y, Kawano S, Kamitani T, Yoshiura K., The application of a gamma distribution model to diffusion-weighted images of the orofacial region, Dentomaxillofac Radiol, doi: 10.1259/dmfr.20200252., 2020.08, Objectives: This study evaluated the correlation among the diffusion-derived parameters obtained by monoexponential (ME), intravoxel incoherent motion (IVIM) and γ distribution (GD) models and compared these parameters among representative orofacial tumours. Methods: Ninety-two patients who underwent 1.5 T MRI including diffusion-weighted imaging were included. The shape parameter (κ), scale parameter (θ), ratio of the intracellular diffusion (ƒ1), extracellular diffusion (ƒ2) and perfusion (ƒ3) were obtained by the GD model; the true diffusion coefficient (D) and perfusion fraction (f) were obtained by the IVIM model; and the apparent diffusion coefficient (ADC) was obtained by the ME model. Results: ƒ1 had a strongly negative correlation with the ADC (ρ = -0.993) and D (ρ = -0.926). A strong positive correlation between f and ƒ3 (ρ = 0.709) was found. Malignant lymphoma (ML) had the highest ƒ1, followed by squamous cell carcinoma (SCC), malignant salivary gland tumours, pleomorphic adenoma (Pleo) and angioma. Both the IVIM and GD models suggested the highest perfusion in angioma and the lowest perfusion in ML. The GD model demonstrated a high extracellular component in Pleo and revealed that the T4a+T4b SCC group had a lower ƒ2 than the T2+T3 SCC group, and poor to moderately differentiated SCC had a higher ƒ1 than highly differentiated SCC. Conclusions: Given the correlation among the diffusion-derived parameters, the GD model might be a good alternative to the IVIM model. Furthermore, the GD model's parameters were useful for characterizing the pathological structure.. |
7. | Panyarak, W., Chikui, T., Tokumori, K., Yamashita Y, Kamitani T., Togao, O., Yoshiura, K., Utility of a diffusion kurtosis model in the differential diagnosis of orofacial tumours, Clinical Radiology, doi: 10.1016/j.crad.2020.01.008., 75, 7, 507-519, 2020.07, AIM: To compare the goodness of fit and correlations between diffusion kurtosis imaging (DKI) and a mono-exponential (ME) model, to compare the corrected apparent diffusion coefficient (Dapp) and apparent kurtosis (Kapp) of the DKI model, and the apparent diffusion coefficient (ADC) of the ME model among the various orofacial lesions, and to evaluate the diagnostic performances between the two models. MATERIALS AND METHODS: A total of 100 orofacial lesions underwent echo-planar diffusion magnetic resonance imaging (MRI) with four b-values. The goodness of fit was evaluated using Akaike information criterion. The correlations of the diffusion-derived parameters were evaluated. The diagnostic performance was analysed by receiver operating characteristics (ROC). RESULTS: The DKI model showed a significantly better goodness of fit than the ME model (p |
8. | WannakamonPanyarak, Toru Chiku, Yasuo Yamashita, Takeshi Kamitani, Kazunori Yoshiura., Image Quality and ADC Assessment in Turbo Spin-Echo and Echo-Planar Diffusion-Weighted MR Imaging of Tumors of the Head and Neck, Academic Radiology, https://doi.org/10.1016/j.acra.2018.11.016, 2018.12, Rationale and Objectives We aimed to compare the distortion ratio (DR), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) between turbo spin-echo (TSE)-diffusion-weighted imaging (DWI) and echo-planar imaging (EPI)-DWI of the orofacial region and prove the usefulness of TSE-DWI for the differential diagnosis of orofacial lesions. Materials and methods The DR, SNR, and CNR of both sequences were compared in 42 cases. Then, the apparent diffusion coefficient (ADC) of various orofacial lesions obtained by TSE-DWI was investigated in 143 lesions. Results In the first study, 38 of 42 cases were analyzed. TSE-DWI showed a significantly lower DR (p Conclusion TSE-DWI produced better quality images than EPI-DWI. TSE-DWI yields the high possibility of obtaining ADC in the orofacial region, and this value was considered useful for the differential diagnosis of orofacial lesions.. |
9. | Chikui T, Yamashita Y, Kise Y, Saito T, Okamura K, Yoshiura K., Estimation of proton density fat fraction of the salivary gland., Br J Radiol, doi: 10.1259/bjr.20170671., 91, 1085, 2018.05, OBJECTIVE: Our first objective was to prove the validity of the six-point Dixon method for estimating the proton density fat fraction (PDFF) of the salivary gland. The second objective was to estimate the salivary gland PDFF using Dixon method to evaluate the pathological conditions. METHODS: At first, 12 volunteers underwent two types of sequences: single-voxel magnetic resonance spectroscopy and the Dixon method and the PDFFs obtained by the two methods were compared. Next, a total of 67 individuals [normal, n = 46; Sjögren's syndrome (SS), n = 11; and IgG4-related dacryoadenitis and sialadenitis (IgG4-DS), n = 4, parotitis, n = 6] were enrolled to estimate the parotid gland (PG) and submandibular gland (SMG) PDFF using the Dixon method. RESULTS: This volunteer study demonstrated excellent correlation between two methods (R2 = 0.964, slope = 1.05). In the normal group, the PG-PDFF was correlated with the weight and body mass index (BMI) (ρ = 0.38, p = 0.0085; and ρ = 0.63, p CONCLUSION: The Dixon method is a feasible method for estimating the PDFF and demonstrates fat accumulation in SMG in the SS group. Advances in knowledge: The PDFF obtained by the Dixon method is helpful for understanding the salivary gland pathological condition.. |
10. | Yoshitaka Kise, Toru Chikui, Yasuo Yamashita, Kouji Kobayashi, Kazunori Yoshiura, Clinical usefulness of the mDIXON Quant the method for estimation of the salivary gland fat fraction: Comparison with MR spectroscopy., Br J Radiol., doi.org/10.1259/bjr.20160704, 2017.07, To estimate the fat fraction (FF) in the salivary glands (SGs) by the mDIXON method and the MRS method, and to compared the results. METHODS: Sixteen healthy volunteers were enrolled. mDIXON Quant and MRS (point-resolved spectroscopy: PRESS) with a single TE were employed to measure the FF in the parotid gland (PG) and submandibular gland (SMG). Multiple TEs were applied in 10 volunteers to correct for T2 decay. In addition, we assumed that the 1.3 ppm peak accounted for 60% of the total fat peak and estimated the FF (MRS all) as a gold standard. On mDIXON Quant images, VOIs were set on the bilateral SGs and we obtained the FF (mDIXON) of each VOI. RESULTS: There was a strong correlation between the results of the mDIXON Quant method and the MRS (single TE) method (R2=0.960, slope=0.900). Using PRESS with multiple TEs, there was also a strong correlation between FF (mDIXON) and FF (MRS all) (R2=0.963, slope=1.18). FF (MRS all) was 24.9 ± 12.7% in the PG and 4.5 ± 3.0% in the SMG, while FF (mDIXON) was 29.4 ± 16.2% in the PG and 6.4 ± 4.7% in the SMG. There were no significant differences between the two methods, but the Bland-Altman plot showed that FF (mDIXON) was slightly larger than FF (MRS all) for small FF areas. CONCLUSIONS: The mDIXON Quant method could be clinically useful for evaluating the FF of SGs, but the absolute values need careful interpretation Advance in knowledge: This study suggested the potential clinical usefulness of the mDIXON Quant method for the SGs.. |
11. | Toru Chiikui, Erina KItamoto, Yukiko Nishioka Kami, Shintaro Kawano, Kouji Kobayashi, Takeshi Kamitani, Makoto Obara, Kazunori Yoshiura, Dynamic contrast-enhanced MRI of oral squamous cell carcinoma: A preliminary study of the correlations between quantitative parameters and the clinical stage., Br J Radiol., org/10.1259/bjr.20140814, 2015.04, To probe the utility of dynamic contrast-enhanced (DCE) -MRI parameters in assessing the clinical characteristics of oral squamous cell carcinoma. METHODS: A total of 85 tumors were included. We applied the Tofts and Kermode model for the DCE-MRI data, and obtained three dependent parameters: the influx forward volume transfer constant into the extravascular extracellular space (EES) from the plasma (Ktrans), the fractional volume of EES per unit volume of tissue (ve) and the fractional volume of plasma (vp). We evaluated the correlations between these parameters and the clinical stages. RESULTS: The T stage showed a negative correlation with the Ktrans (r = -0.2272, P = 0.0365), but it did not show a significant correlation with the other parameters. The N stage showed a negative correlation with Ktrans (r = -0.1948, P = 0.0404), and there were significant differences between N1 and N2+3 (0.119±0.027 min-1 vs 0.096±0.023 min-1, P = 0.0198) and between N0 and N2+3 (0.114±0.29 min-1 vs 0.096±0.023 min-1, P = 0.0288). CONCLUSIONS: A decrease in the Ktrans at the primary site was found in advanced N stage cases, which might indicate that the hypoxic status cause a high possibility of the metastasis. Advances in knowledge: A decrease in the Ktrans at the primary site suggested the high possibility of an advanced N stage.. |
12. | Erina Kitamoto, Toru Chikui, Shintaro Kawano, Masahiro Ohga, Kouji Kobayashi, Yoshio Matsuo, Takashi Yoshiura, Makoto Obara, Hiroshi Honda, Kazunori Yoshiura, The application of dynamic contrast-enhanced MRI and diffusion-weighted MRI in patients with maxillofacial tumors., Academic Radiology, org/10.1016/j.acra.2014.08.016, 22, 2, 210-216, 2015.02, To elucidate the characteristics of four types of tumors, including squamous cell carcinoma (SCC), malignant lymphoma (ML), malignant salivary gland tumors (MSGTs), and pleomorphic adenoma (Pleo), in the maxillofacial region using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted MRI (DW-MRI)data. MATERIALS AND METHODS: A total of 59 tumors were included in this research. DCE-MRI and DW-MRI were performed. We applied the Tofts and Kermode model (TK model) for the DCE-MRI data and obtained three dependent parameters: the influx forward volume transfer constant into the extravascular extracellular space from the plasma (K(trans)), the fractional volume of extravascular extracellular space per unit volume of tissue (ve), and the fractional volume of plasma (vp). RESULTS: Among the K(trans) values, there were no significant differences between the three types of malignant tumors; however, there was a significant difference between the SCC and Pleo (P = .0099). The ve values of the Pleo were highest, with significant differences compared to the other categories (SCC, P = .0012; ML, P = .0017; and MSGT, P = .041). The ML had the lowest ve values, and there were significant differences between ML and the other two types of malignant tumors (SCC, P = .0278 and MSGT, P = .0062). In 14 (24%) cases, apparent diffusion coefficient (ADC) could not be measured because of poor image quality. The ADC values of the ML were lowest, whereas those of Pleo were highest, similar to that observed for ve. CONCLUSIONS: The Pleo tumors had lower K(trans) values and higher ve values, which are useful for differentiating them from the malignant tumors. Moreover, the ve was also useful for establishing a diagnosis of ML.. |
13. | Chikui T, Obara M, Simonetti AW, Ohga M, Koga S, Kawano S, Matsuo Y, Kamintani T, Shiraishi T, Kitamoto E, Nakamura K, Yoshiura K., The principal of dynamic contrast enhanced MRI, the method of pharmacokinetic analysis, and its application in the head and neck region., Int J Dent, doi: 10.1155/2012/480659, 2012.11, The principal of dynamic contrast enhanced MRI, the method of pharmacokinetic analysis, and its application in the head and neck region.. |
14. | Chikui T, Kitamoto E, Kawano S, Sugiura T, Obara M, Simonetti AW, Hatakenaka M, Matsuo Y, Koga S, Ohga M, Nakamura K, Yoshiura K, Pharmacokinetic analysis based on dynamic contrast-enhanced MRI for evaluating tumor response to preoperative therapy for oral cancer., J Magn Reson Imaging, doi: 10.1002/jmri.23704, 2012.06, 口腔扁平上皮ガンにおける、術前科学放射線の治療効果判定を、MRIのダイナミック撮影をコンパートメントモデル解析を用いる事により評価可能であるか検討した。治療高価判定としては、組織学的効果を大星、下里分類を用い、 gold standardとした。コンパートメントモデル解析から得られる、血管外細胞外のスペースveの変化量が、組織学的効果判定と相関する事を明らかにした。すなわわち、腫瘍細胞の減少による血管外細胞外スペースの割合の増加をMRでとらえる事が可能であることを示した。. |
15. | Matsubara R, Kawano S, Chikui T, Kiyosue T, Goto Y, Hirano M, Jinno T, Nagata T, Oobu K, Abe K, Nakamura S., Clinical Significance of Combined Assessment of the Maximum Standardized Uptake Value of F-18 FDG PET with Nodal Size in the Diagnosis of Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma. , Acad Radiol, 19, 6, 708-17, 2012.06. |
16. | Chikui T, Kawano S, Kawazu T, Hatakenaka M, Koga S, Ohga M, Matsuo Y, Sunami S, Sugiura T, Shioyama Y, Obara M, Yoshiura K., Prediction and monitoring of the response to chemoradiotherapy in oral squamous cell carcinomas using a pharmacokinetic analysis based on the dynamic contrast-enhanced MR imaging findings., Eur Radiol, DOI: 10.1007/s00330-011-2102-x, 2011 Aug;21(8), 2011.08. |
17. | Shiraishi T, Chikui T, Yoshiura K, Yuasa K., Evaluation of T2 values and apparent diffusion coefficient of the masseter muscle by clenching., Dentomaxillofac Radiol. , 40, (1), 35-41., 2011.01. |
18. | Chikui T, Shiraishi T, Tokumori K, Inatomi D, Hatakenaka M, Yuasa K, Yoshiura K., Assessment of the sequential change of the masseter muscle by clenching: a quantitative analysis of T1, T2, and the signal intensity of the balanced steady-state free precession., Acta Radiol., 51, 6, 669-78., 2010.07. |
19. | TORU CHIKUI, TOMOKO SHIRAISHI, TAKAHIRO ICHIHARA, TOSHIYUKI KAWAZU, MASAMITSU HATAKENAKA, YUKIKO KAMI, KENJI YUASA , KAZUNORI YOSHIURA, Effect of clenching on T2 and diffusion parameters of the masseter muscle, Acta Radiologica, 51, 1, 58-63, 2010.01. |
20. | Toru Chikui, Mayumi Shimizu, Toshiyuki Kawazu, Kazutoshi Okamura, Tomoko Shiraishi, Kazunori Yoshiura, A quantitative analysis of sonographic images of the salivary gland: A comparison between the sonographic findings and the sialographic findings, UltrasoundinMed.&Biol., 35(8):1257-1264, 2009.08. |
21. | 筑井徹、瀬々良介、市原隆洋、湯浅賢治、吉浦一紀, 2D-Look-Locker sequence を使用したT1計測の試み, 歯科放射線学会雑誌, 47(2):65-74, 2007.06. |
22. | TORU CHIKUI, KAZUTOSHI OKAMURA, KENJI TOKUMORI, SEIJI NAKAMURA, Quantitative Analyses of Sonographic images of the parotid gland in patient with Sjogren's syndrome., Ultrasound in Med. & Biol., Vol. 32, No. 5, pp. 617- 622, 2006, 2006.05. |
23. | Toru Chikui, Kenji Yuasa1, kenji Tokumori, Shigenobu Kanda, Naonobu Kunitake, Katsumasa Nakamura,, Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy, European Radiology, 10.1007/s00330-003-2173-4, 14, 7, 1255-1262, (2004) 14:1255–1262, 2004.07. |
24. | 筑井徹,湯浅賢治,神田重信,中村和正,長田哲次,平木昭光, 術前放射線治療による頸部リンパ節の超音波所見の変化について, 頭頸部腫瘍, Vol.28,pp.211-217, 2002.03. |
25. | Chikui T., Yonetsu K., Nakamura T., Multivariate feature analysis of sonographic findings of metastatic cervical lymph nodes: contribution of blood flow features revealed by power Doppler sonography for predicting metastasis, AJNR Am J Neuroradiol., Vol.21,No.3,pp.561-567, 2000.05. |
主要総説, 論評, 解説, 書評, 報告書等
主要学会発表等
学会活動
学協会役員等への就任
2024.04~2026.03, 日本歯科放射線学会, 理事.
2012.04~2014.03, 日本歯科放射線学会, 代議員.
2008.07~2008.10, 日本歯科放射線学会, 認定委員会問題作成委員.
2008.04, 日本歯科放射線学会, 評議員.
2007.05, 日本歯科放射線学会, 医療情報委員会.
2006.08, 日本歯科放射線学会, ガイドライン策定委員.
学会大会・会議・シンポジウム等における役割
2023.05.26~2023.05.28, NPO法人日本歯科放射線学会第63回学術大会・第19回定例総会, 準備委員長.
2023.05.26~2023.05.28, NPO法人日本歯科放射線学会第63回学術大会, 座長(教育講演1).
2022.10.08~2022.10.09, NPO法人日本歯科放射線学会第3回秋季臨床大会, 教育講演演者.
2022.10.08~2022.10.09, NPO法人日本歯科放射線学会第3回秋季臨床大会, 座長.
2022.06.25~2022.06.25, 全国歯科大学・歯学部附属病院診療放射線技師連絡協議会 2022年度 歯科放射線技術研修会, 教育講演演者.
2019.11.22~2019.11.23, 第24回臨床画像大会, 座長.
2017.11.26~2017.11.26, 日本歯科放射線学会 教育研修会「第29回 実技研修会・超音波診断」, 教育講演演者.
2017.11.25~2017.11.25, 第 50 回 NPO 法人日本口腔科学会九州地方部会教育研修会, シンポジスト.
2017.07.29~2017.07.29, 第19回 日本口腔顎顔面外傷学会総会・学術大会, シポジスト.
2017.06.03~2017.06.04, NPO法人 日本歯科放射線学会 第58回学術大会・第14回定例総会, 座長.
2017.06.03~2017.06.04, NPO法人 日本歯科放射線学会 第58回学術大会・第14回定例総会, 座長(Chairmanship).
2016.12.10~2016.12.10, NPO 法人 日本歯科放射線学会 第36回関西・九州合同地方会, 準備委員長.
2015.10.25~2015.10.25, 第28回生涯学習研修会(歯科エックス線優良医講習会), 実施責任者.
2012.12.08~2012.12.08, 日本歯科放射線学会第32回関西・九州合同地方会, 座長(Chairmanship).
2012.05.19~2012.05.20, 第72回九州歯科学会総会学術大会, シンポジスト.
2011.12.10~2011.12.10, 日本歯科放射線学会第31回関西・九州合同地方会, 座長(Chairmanship).
2011.05.25~2011.05.29, 18th International Congress of Dento-Maxillo-Facial Radiology, 座長(Chairmanship).
2010.12.11~2010.12.11, 日本歯科放射線学会 第49回九州地方会・第53回関西地方会, 座長(Chairmanship).
2009.10.24~2009.10.26, 日本歯科放射線学会 臨床画像大会, 座長(Chairmanship).
2008.05.16~2008.05.16, 日本歯科放射線学会 学術大会, 座長(Chairmanship).
2008.05~2008.05, 日本歯科放射線学会第49回学術大会, 座長.
2005.12~2005.12, 第42回九州・第48回関西合同地方会, 座長.
2005.12~2005.12, 日本歯科放射線学会 九州、関西合同地方会, 座長(Chairmanship).
2005.08~2005.08, 日本歯科放射線学会 九州地方会, 座長(Chairmanship).
2005.05~2005.05, 第45回 日本歯科放射線学会総会, シンポジスト.
2004.11~2004.11, 第40回九州・第47回関西合同地方会, 座長.
2004.11~2004.11, 日本歯科放射線学会 関西、九州合同地方会, 座長(Chairmanship).
2003.09~2003.09, 第44回 日本歯科放射線学会, ゲストスピーカー(学会賞受賞講演).
2003.05~2003.05, 第8回 臨床画像大会, 座長.
2002.10~2002.10, 第43回 日本歯科放射線学会総会, シンポジスト.
2002.05~2002.05, 日本歯科放射線学会 臨床画像大会 , 座長(Chairmanship).
学会誌・雑誌・著書の編集への参加状況
2021.02~2022.03, Journal of Advanced Oral Science, 国際, Journal of Advanced Oral Sciences (Chiang Mai Dental Journal).
2012.05~2013.01, Internal journal of Dentistry. (Special issue on New Current and Advanced Diagnositic Imaging for Oral and Maxillofacial Disease.), 国際, 編集委員.
学術論文等の審査
年度 | 外国語雑誌査読論文数 | 日本語雑誌査読論文数 | 国際会議録査読論文数 | 国内会議録査読論文数 | 合計 |
---|---|---|---|---|---|
2023年度 | 7 | 7 | |||
2022年度 | 7 | 7 | |||
2021年度 | 7 | 7 | |||
2020年度 | 12 | 12 | |||
2019年度 | 8 | 8 | |||
2018年度 | 8 | 8 | |||
2017年度 | 9 | 9 | |||
2016年度 | 9 | 0 | 0 | 0 | 9 |
2015年度 | 12 | 12 | |||
2014年度 | 8 | 8 | |||
2013年度 | 6 | 6 | |||
2012年度 | 5 | 5 | |||
2011年度 | 6 | 6 | |||
2010年度 | 6 | 6 | |||
2009年度 | 0 | 1 | 0 | 0 | 1 |
2006年度 | 1 | 0 | 0 | 0 | 1 |
その他の研究活動
海外渡航状況, 海外での教育研究歴
チュラロンコーン大学, コンケーン大学, Thailand, Thailand, 2000.12~2000.12.
チェンマイ大学, Thailand, 2002.12~2002.12.
受賞
JMRI Reviewer Awards, International Society for Magnetic Resonance in Medicine, 2018.08.
優秀発表賞, 日本矯正歯科学会, 2013.10.
Yoshida Award, NPO法人日本歯科放射線学会, 2008.11.
優秀論文賞, 日本歯科放射線学会, 2003.10.
研究資金
科学研究費補助金の採択状況(文部科学省、日本学術振興会)
2019年度~2021年度, 基盤研究(C), 分担, Compressed sensingを用いた頭頸部病変の高時間分解能血流動態評価.
2018年度~2020年度, 基盤研究(C), 代表, 統計学modelを用いた拡散情報と薬物動態解析の総合評価 頭頸部への応用.
2015年度~2017年度, 基盤研究(C), 代表, 顎顔面部における可動性蛋白質/ペプチドの化学交換イメージングの検討.
2012年度~2014年度, 基盤研究(C), 代表, MRIによる頭頸部病変のpermeabilityおよびperfusionの総合評価.
2009年度~2011年度, 基盤研究(C), 代表, HーMRI、PーMRSによる咬合の咀嚼筋に及ぼす影響の画像的評価.
2009年度~2011年度, 基盤研究(C), 分担, 歯科用コーンビームCT検査の最適化のための総合的CT性能評価法の開発.
2006年度~2008年度, 一般研究(C), 分担, 造影MRIを用いた頭頸部Kinetic Analysisの試み.
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