Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Shigeki Furuya Last modified date:2021.07.16

Professor / Division of Systems Bioengineering / Department of Bioscience and Biotechnology / Faculty of Agriculture


Papers
1. Weiyong Shen, So-Ra Lee, Ashish Easow Mathai, Rui Zhang, Jianhai Du, Michelle X. Yam, Victoria Pye, Nigel L. Barnett, Cassie L. Rayner, Ling Zhu, James B. Hurley, Pankaj Seth, Yoshio Hirabayashi, Shigeki Furuya, Mark C. Gillies, Effect of selectively knocking down key metabolic genes in Muller glia on photoreceptor health, Glia, 10.1002/glia.24005, 69, 8, 1966-1986, 2021.08.
2. Momoko Hamano, Shozo Tomonaga, YUsuke Osaki, Hiroaki Oda, HIsanori Kato, Shigeki Furuya., Transcriptional activation of Chac1 and other Atf4-target genes induced by extracellular L-serine depletion is negated with glycine consumption in Hepa1-6 hepatocarcinoma cells., Nutrients, doi.org/10.3390/nu12103018, 12, 10, 3018, 2020.10.
3. Takashi Ichinose, Hiroyasu Murasawa, Tomoko Ishijima, Shinji Okada, Keiko Abe, Saki Matsumoto, Toshiro Matsui, Shigeki Furuya, Tyr-Trp administration facilitates brain norepinephrine metabolism and ameliorates a short-term memory deficit in a mouse model of Alzheimer’s disease., PLoS One, 10.1371/journal.pone.0232233, 15, 5, e0232233, 2020.05.
4. Juliette Le Douce, Marianne Maugard, Julien Veran, Marco Matos, Pierrick Jégo, Pierre-Antoine Vigneron, Emilie Faivre, Xavier Toussay, Michel Vandenberghe, Yaël Balbastre, Juliette Piquet, Elvire Guiot, Nguyet Thuy Tran, Myriam Taverna, Stéphane Marinesco, Ayumi Koyanagi, Shigeki Furuya, Mylène Gaudin-Guérif, Sébastien Goutal, Aurélie Ghettas, Alain Pruvost, Alexis-Pierre Bemelmans, Marie-Claude Gaillard, Karine Cambon, Lev Stimmer, Véronique Sazdovitch, Charles Duyckaerts, Graham Knott, Anne-Sophie Hérard, Thierry Delzescaux, Philippe Hantraye, Emmanuel Brouillet, Bruno Cauli, Stéphane H R Oliet, Aude Panatier, Gilles Bonvento, Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease., Cell Metabolism, https://doi.org/10.1016/j.cmet.2020.02.004., 31, 3, 503-517, .e8, 2020.03, [URL], Alteration of brain aerobic glycolysis is often observed early in the course of Alzheimer’s disease (AD). Whether and how such metabolic dysregulation contributes to both synaptic plasticity and behavioral deficits in AD is not known. Here, we show that the astrocytic L-serine biosynthesis pathway, which branches from glycolysis, is impaired in young AD mice and in AD patients. L-serine is the precursor of D-serine, a co-agonist of synaptic NMDA receptors (NMDARs) required for synaptic plasticity. Accordingly, AD mice display a lower occupancy of the NMDAR co-agonist site as well as synaptic and behavioral deficits. Similar deficits are observed following inactivation of the L-serine synthetic pathway in hippocampal astrocytes, supporting the key role of astrocytic L-serine. Supplementation with L-serine in the diet prevents both synaptic and behavioral deficits in AD mice. Our findings reveal that astrocytic glycolysis controls cognitive func- tions and suggest oral L-serine as a ready-to-use therapy for AD..
5. Yui Kawano, Hu Yating, Masahiro Sasaki, Shigeki Furuya, Silk sericin intake leads to increases in L-serine and L-tyrosine levels in the mouse brain and the simultaneous facilitation of brain noradrenergic turnover, Bioscience, Biotechnology and Biochemistry, 10.1080/09168451.2019.1676693, 84, 2, 372-379, 2020.02.
6. M. R. Haque, A. Hirowatari, F. Saruta, S. Furuya, K. Yamamoto, Molecular survey of the phosphoserine phosphatase involved in L-serine synthesis by silkworms (Bombyx mori), Insect Molecular Biology, 10.1111/imb.12609, 29, 1, 48-55, 2020.02.
7. Mohammad R. Haque, Aiko Hirowatari, Nonoko Nai, Shigeki Furuya, Kohji Yamamoto, Serine hydroxymethyltransferase from the silkworm Bombyx mori
Identification, distribution, and biochemical characterization, Archives of insect biochemistry and physiology, 10.1002/arch.21594, 102, 2, 2019.10.
8. Mohammad R. Haque, Aiko Hirowatari, Ayumi Koyanagi, Takashi Ichinose, Maiko Abiru, Shinya Mohri, Shigeki Furuya, Kohji Yamamoto, Molecular characterization and expression analysis of a phosphoserine aminotransferase involving L-serine synthesis from silkworm, Bombyx mori, Archives of insect biochemistry and physiology, 10.1002/arch.21553, 101, 2, 2019.06.
9. Mohammad R. Haque, Akifumi Higashiura, Atsushi Nakagawa, Aiko Hirowatari, Shigeki Furuya, Kohji Yamamoto, Molecular structure of a 5,10-methylenetetrahydrofolate dehydrogenase from the silkworm Bombyx mori, FEBS Open Bio, 10.1002/2211-5463.12595, 9, 4, 618-628, 2019.04, The enzyme 5,10-methylenetetrahydrofolate dehydrogenase (MTHFD) is essential for the production of certain amino acids (glycine, serine, and methionine) and nucleic acids (thymidylate and purine). Here, we identified a cDNA encoding this enzyme from the silkworm Bombyx mori. The recombinant B. mori MTHFD (bmMTHFD) expressed in Escherichia coli recognized 5,10-methylenetetrahydrofolate and 5,10-methenyltetrahydrofolate as substrate in the presence of NADP + as well as NAD + . The bmMTHFD structure was determined at a resolution of 1.75 Å by X-ray crystallography. Site-directed mutagenesis indicated that the amino acid residue Tyr49 contributed to its catalytic activity. Our findings provide insight into the mechanism underlying the activity of MTHFD from B. mori and potentially other insects and may therefore facilitate the development of inhibitors specific to MTHFD as insecticides..
10. Hisatsugu Koshimizu, Nao Hirata, Keizo Takao, Keiko Toyama, Takashi Ichinose, Shigeki Furuya, Tsuyoshi Miyakawa, Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2., Neuropsychopharmacol Rep, https://doi.org/10.1002/npr2.12041, 39, 56-60, 2019.03.
11. Yukako Hino, Ayumi Koyanagi, Motohiro Maebuchi, Takashi Ichinose, Shigeki Furuya, Comparison of the effect of soy and casein-derived peptide administration on tyrosine and catecholamine metabolism in the mouse brain., J. Nutr. Sci. Vitaminol. (Tokyo), https://doi.org/10.3177/jnsv.64.329, 64, 5, 329-334, 2018.11, [URL].
12. Saar Vandekeere, Charlotte Dubois, Joanna Kalucka, Mark R. Sullivan, Melissa García-Caballero, Jermaine Goveia, Rongyuan Chen, Frances F. Diehl, Libat Bar-Lev, Joris Souffreau, Andreas Pircher, Saran Kumar, Stefan Vinckier, Yoshio Hirabayashi, Shigeki Furuya, Luc Schoonjans, Guy Eelen, Bart Ghesquière, Eli Keshet, Xuri Li, Matthew G.Vander Heiden, Mieke Dewerchin, Peter Carmeliet, Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells., Cell Metabolism, https://doi.org/10.1016/j.cmet.2018.06.009, 28, 4, 573-587, .e13, 2018.07, [URL].
13. Momoko Hamano, Yurina Haraguchi, Tomoko Sayano, Chong Zyao, Yashiho Arimoto, Yui Kawano, Kazuki Moriyasu, Miyako Udono, Yoshinori Katakura, Takuya Ogawa, Hisanori Kato, Shigeki Furuya, Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3-phosphoglycerate dehydrogenase-deficient fibroblasts., FEBS Open Bio, 10.1002/2211-5463.12429, 2018.04.
14. Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Nozomu Takaki, Yukihiro Tone, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasuo, Early-life Photoperiod Influences Depression-like Behavior, Prepulse Inhibition of the Acoustic Startle Response, and Hippocampal Astrogenesis in Mice., Neuroscience, 10.1016/j.neuroscience.2018.01.038, 374, 133-143, 2018.03, [URL].
15. Haruka Imai, Kazuki Moriyasu, Akane Nakahata, Motohiro Maebuchi, Takashi Ichinose, Shigeki Furuya, Soy peptide ingestion ingestion augments the synthesis and metabolism of noradrenaline in the mouse brain. , Biosci. Biotech. Biochem. , http://dx.doi.org/10.1080/09168451.2017.1282807, 81, 1007-1013, 2017.05, [URL].
16. Yasufumi Fukano, Nozomu Okino, Shigeki Furuya, Makoto Ito, A label-free impedance-based whole cell assay revealed a new G protein-coupled receptor ligand for mouse microglial cell migration., Biochemical and Biophysical Research Communications, https://doi.org/10.1016/j.bbrc.2016.07.119, 478, 624-630, 2016.09, [URL].
17. Momoko Hamano, Tomoko Sayano, Wataru Kusada, Hisanori Kato, Shigeki Furuya, Microarray data on altered transcriptional program of Phgdh-deficient mouse embryonic fibroblasts caused by L-serine depletion., Data in Brief, DOI: 10.1016/j.dib.2016.04.052, 7, 1598-1601, 2016.05, [URL].
18. Tomoko Sayano, Yuki Kawano, Wataru Kusada, Yashiho Arimoto, Kayoko Esaki, Momoko Hamano, Miyako Udono, Yoshinori Katakura, Takuya Ogawa, Hisanori Kato, Yoshio Hirabayashi, Shigeki Furuya, Adaptive response to L-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts., FEBS Open Bio, DOI: 10.1002/2211-5463.12038, 2016.03, [URL].
19. Kazuki Moriyasu, Takashi Ichinose, Akane Nakahata, Mitsuru Tanaka, Toshiro Matsui, Shigeki Furuya, The Dipeptides Ile-Tyr and Ser-Tyr Exert Distinct Effects on Catecholamine Metabolism in the Mouse Brainstem., Int. J. Pept., http://dx.doi.org/10.1155/2016/6020786, 2016, Article ID 6020786, 2016.02, [URL].
20. Kayoko Esaki, Tomoko Sayano, Chiaki Sonoda, Takumi Akagi, Takeshi Suzuki, Takuya Ogawa, Masahiro Okamoto, Takeo Yoshikawa, Yoshio Hirabayashi, Shigeki Furuya, L-Serine deficiency elicits intracellular accumulation of cytotoxic deoxysphingolipids and lipid body formation. , J. Biol. Chem., 10.1074/jbc.M114.603860, 290, 23, 14595-14609, 2015.06, [URL].
21. Takashi Ichinose, Kazuki Moriyasu, Akane Nakahata, Mitsuru Tanaka, Toshiro Matsui, Shigeki Furuya, Orally administrated dipeptide Ser-Tyr efficiently stimulates noradrenergic turnover in the mouse brain., Biosci. Biotech. Biochem., doi: 10.1080/09168451.2015.1044932, 2015.05.
22. Jeffrey T. Ehmsen, Ting Martin Ma, Hagit Sason, Dina Rosenberg, Tadashi Ogo, Shigeki Furuya, Solomon H. Snyder, Herman Wolosker, D-Serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase., J. Neurosci. , doi: 10.1523/​JNEUROSCI.4914-12.2013, 33, 12464-12469, 2013.07.
23. Keizo Takao, Katsunori Kobayashi, Hideo Hagihara, Koji Ohira, Hirotaka Shoji, Satoko Hattori, Hisatsugu Koshimizu, Juzoh Umemori, Keiko Toyama, Hironori K Nakamura, Mahomi Kuroiwa, Jun Maeda, Kimie Atsuzawa, Kayoko Esaki, Shigeki Furuya, Tsuyoshi Takagi, Noah M Walton, Mitsuyuki Matsumoto, Shunsuke Ishii, Tsuyoshi Miyakawa, Deficiency of Schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. , Neuropsychopharmacology, doi: 10.1038/npp.2013.38., 38, 1409-1425, 2013.07.
24. Kayoko Esaki, Taketo Ohmori, Motohiro Maebuchi, Toshihiro Nakamori, Toshihisa Ohshima, Shigeki Furuya, Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY. , Biosci. Biotech. Biochem. , 77, 847-849, 2013.04.
25. Tomoko Sayano, Yuriko Kawakami, Wataru Kusada, Takeshi Suzuki, Yuki Kawano, Akihiro Watanabe, Kana Takashima, Yashiho Arimoto, Kayoko Esaki, Akira Wada, Fumiaki Yoshizawa, Masahiko Watanabe, Masahiro Okamoto, Yoshio Hirabayashi, Shigeki Furuya, Serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the central nervous system., FEBS J., doi: 10.1111/febs.12146., 280, 1502-1517, 2013.02.
26. Masataka Suzuki, Jumpei Sasabe, Shigeki Furuya, Kenji Hamase, Sadakazu Aiso, Type 1 diabetes mellitus in mice increases hippocampal D-serine in the acute phase after streptozotocin injection. , Brain Res., doi: 10.1016, 1466, 167-176, 2012.05.
27. Esaki, K., Kokido, T., Ohmori, T., Tsukino, M., Ohshima, T., Furuya S., Soy peptide ingestion increases neuroactive amino acids in the adult brain of wild-type and genetically engineered serine-deficient mice., J. Nutr. Food Sci., 10.4172/2155-9600.1000109, 1, 109, 2011.11.
28. Yang, JH., Wada, A., Yoshida, K., Miyoshi, Y., Sayano, T., Esaki, K., Kinoshita, O.M., Tomonaga, S., Azuma, N., Watanabe, M., Hamase, K., Zaitsu, K., Machida, T., Messing, A., Itohara, S., Hirabayashi, Y., Furuya, S.  , Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an NMDA receptor co-agonist, in adult brain., J. Biol. Chem., 285, 41380-41390, 2010.12.
29. Kinoshita, O.M., Furuya, S., Ito, S., Shinoda, Y., Yamazaki, Y., Greimel, P., Ito, Y., Hashikawa, T., Machida, T., Nagatsuka, Y., Hirabayashi, Y. , Lipid rafts enriched in phosphatidylglucoside direct astroglial differentiation by regulating tyrosine kinase activity of EGF receptors., Biochem. J. , 419, 565-575, 2009.05.
30. Kawakami, Y., Yoshida, K., Yang, J.H., Suzuki, T., Azuma, N., Tanaka, H., Watanabe, M., Kuhara, S., Hirabayashi, Y., Furuya, S. , Impaired neurogenesis in the embryonic spinal cord of Phgdh knockout mouse, a serine deficiency disorder model. , Neurosci. Res., 63, 184-193, 2009.03.
31. Kinoshita, O.M., Shinoda, Y., Sakai, K., Hashikawa, T., Watanabe, M., Machida, T., Hirabayashi, Y., Furuya, S. , Selective up-regulation of 3-phosphoglycerate dehydrogenase (Phgdh) expression in adult subventricular zone neurogenic niche., Neurosci. Lett. , 453, 21-26., 2009.03.
32. Hirabayashi, Y., Furuya, S. , Roles of L-serine and sphingolipid synthesis in brain development and neuronal survival., Prog. Lipid Res, 47, 3, 188-203., 2008.02.
33. Furuya, S., An essential role for de novo synthesis of L-serine in CNS development. , Asia Pac J Clin Nutr. , 17, S1, 307-310., 2008.01.
34. Furuya, S., Yoshida, K., Kawakami,Y., Yang, J-H., Sayano, T., Azuma, N., Tanaka, H., Kuhara, S., Hirabayashi, Y. , Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: Changes in gene expression and associated regulatory networks resulting from serine deficiency. , Funct. Integr. Genomics. , 8, 235-249, 2008.07.
35. Shigeki Furuya, Cell specific expression of neutral glycosphingolipids in vertebrate brain: Immunochemical localization of 3-O-acetyl-sphingosine-series glycolipid(s) in myelin and oligodendrocytes., J. Neurosci. Res. , 85, 2856-2862, 2007.04.
36. Shigeki Furuya, Stathmin, a microtubule destabilizer, mediates the development of dendritic arbors in neuronal cells. , J. Cell Sci. , 120, 1447-1456., 2007.04.
37. Bae, J.-S., Furuya, S., Ahn, S.-J., Yi, S.-J., Shinoda, Y., Hirabayashi, Y., Jin, H.-K., Neuroglial activation in Niemann-Pick Type C mice is suppressed by intracerebral transplantation of bone marrow-derived mesenchymal stem cells., Neurosci. Lett., 381, 234-236, 2005.08.
38. Bae, J.-S., Furuya, S., Shinoda, Y., Endo, S., Schuchman, E. H., Hirabayashi, Y., Jin, H.-K., Neurodegeneration augments the ability of bone marrow-derived mesenchymal stem cells to fuse with Purkinje neurons in Niemann-Pick type C mice., Human Gene Therapy, 16, 1006-1011, 2005.09.
39. Satoi, H., Tomimotoa, H., Ohtani, R., Kitano, T., Kondo, T., Watanabe, M., Oka, N, , I. Akiguchi, I., Furuya, S., Hirabayashi, Y. and Okazaki, T., Astroglial expression of ceramide in Alzheimer's disease brains: A role during neuronal apoptosis., Neuroscience, 130, 657-666, 2005.04.
40. Yoshida, K., Furuya, S., Osuka, S., Mitoma, J., Shinoda, Y., Watanabe, M., Azuma, N., Tanaka, H., Hashikawa, T., Itohara, S., and Hirabayashi, Y., Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality., J. Biol. Chem., 279, 3573-3577, 2004.04.
41. Shimizu, M., Furuya, S., Shinoda, Y., Mitoma, J., Okamura, T., Miyoshi, I., Kasai, N., Hirabayashi, Y., Suzuki, Y., Functional analysis of mouse 3-phosphoglycerate dehydrogenase (Phgdh) gene promoter in developing brain., J. Neurosci. Res., 76, 623-632, 2004.06.
42. Mitoma, J., Furuya, S., Shimizu, M., Shinoda, Y., Yoshida, K., Azuma, N., Tanaka, H., Suzuki, Y., Hirabayashi, Y., Mouse 3-phosphoglycerate dehydrogenase gene: Genomic organization, chromosomal localization, and promoter analysis., Gene, 334, 15-22, 2004.05.
43. Shigeki Furuya, Functional identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat neurons in primary culture., Neurosci Res., 49, 101-111, 2004.09.
44. Shigeki Furuya, Selective expression of L-serine synthetic enzyme 3PGDH in Schwann cells, perineuronal glia and endoneurial fibroblasts in rat sciatic nerves and its upregulation after crush injury., Arch. Histol. Cytol, 66, 429-436, 2003.10.
45. Shigeki Furuya, Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture., FEBS Lett., 548, 69-73, 2003.10.
46. Furuya, S. and Watanabe, M., Novel neuroglial and glioglial relationships mediated by L-serine metabolism., Arch. Histol. Cytol., 66, 109-121, 2003.11.
47. Chen, P., Peng, C., Luff, J., Spring, K., Watters, D., Bottle, S., Fururya, S. and Lavin, M.F., Oxidative stress is responsible for deficient survival and dendritogenesis in Purkinje neurons from Atm mutant mice., J. Neurosci., 23, 11453-11460, 2003.12.
48. Chen, N., Furuya, S., Shinoda, Y., Yumoto, M., Ohtake, A., Sato, K., Doi, H., Hashimoto, Y., Kudo, Y., and Higashi, H., Extracellular carbohydrate-signal triggering PKA-dependent neuronal actin-reorganization., Neuroscience, 122, 985-995, 2003.09.
49. Chen, N., Furuya, S., Doi, H., Hashimoto, Y., Kudo, Y., and Higashi, H., Ganglioside/Calmodulin kinase II signal inducing cdc42-mediated neuronal actin-reorganization., Neuroscience, 120, 163-176, 2003.04.
50. Sakai, K., Shimizu, K., Koike, T., Furuya, S, and Watanabe, M., Neutral amino acid transporter ASCT1 is preferentially expressed in L-Ser-synthetic/storing glial cells in the mouse brain with transient expression in developing capillaries., J. Neurosci., 23, 550-560, 2003.04.
51. Hartell, N.A., Furuya, S., Jacoby, S., and Okada, D., Intercellular action of nitric oxide increases cyclic GMP in cerebellar Purkinje cells., Neuroreport, 12, 25-28, 2001.06.
52. Sugishita, H., Kuwabara Y., Toku K., Doi L., Yang L., Mitoma J., Furuya S., Hirabayashi Y., Maeda N., Sakanaka M., and Tanaka J., L-Serine regulates the activities of microglial cells that express very low level of 3-phosphoglycerate dehydrogenase, an enzyme for L-serine biosynthesis., J. Neurosci. Res., 64, 392-401, 2001.11.
53. Furuya, S., Tabata, T., Mitoma, J., Yamada, K., Yamasaki, M., Makino, A., Yamamoto, T., Watanabe, M., Kano, M., and Hirabayashi, Y., L-Serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons., Proc. Natl. Acad. Sci. USA, 97, 11528-11533, 2000.10.
54. Tabata, T., Sawada, S., Araki, K., Bono, Y., Furuya, S., and Kano, M., A reliable method for culture of dissociated mouse cerebellar cells enriched for Purkinje neurons., J. Neurosci. Methods., 104, 45-53, 2000.11.
55. Okudaira S., Ikeda, Y., Kondo, S., Furuya, S., Hirabayashi, Y., Koyano, T., Saito, Y., and Umezawa, K., Inhibition of acidic sphingomyelinase by xanthone compounds isolated from Gracinia speciosa., J. Enzyme Inhib., 15, 129-138, 2000.06.
56. Furuya, S., Makino, A., and Hirabayashi, Y., An improved method for culturing cerebellar Purkinje cells with differentiated dendrites under a mixed monolayer setting., Brain Res. Protocols, 3, 192-198, 1998.06.
57. Mitoma, J., Kasama, T., Furuya, S., and Hirabayashi, Y., Occurrence of an unusual phospholipid, phosphatidyl-L-threonine, in cultured hippocampal neurons: Exogenous L-serine is required for the syntheses of neuronal phosphatidyl-L-serine and sphingolipids., J. Biol. Chem., 273, 19363-19366, 1998.08.
58. Furuya, S., Mitoma, J., Makino, A., and Hirabayashi, Y., Ceramide and its interconvertable metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells., J. Neurochem., 71, 366-377, 1998.10.
59. Mitoma, J., Furuya, S., and Hirabayashi, Y., A novel metabolic communication between neurons and astrocytes: Non-essential amino acid L-serine released from astrocytes is essential for developing hippocampal neurons., Neurosci. Res., 30, 195-199, 1998.11.
60. Mitoma, J., Ito, M., Furuya, S., and Hirabayashi, Y., Bipotential role of ceramide in the growth of hippocampal neurons: Promotion of cell survival and dendritic elongation in dose- and developmental stage-dependent manners., J. Neurosci. Res., 10.1002/(SICI)1097-4547(19980315)51:6<712::AID-JNR5>3.0.CO;2-E, 51, 6, 712-722, 51, 712-722, 1998.11.
61. Yamane, Y., Tohno-oka, R., Yamada, S., Furuya, S., Hirabayashi, Y., Sugino, H., and Sugahara, K., Molecular characterization of Xenopus embryo heparan sulfate: Different structural requirements for the specific binding to basic fibroblast growth factor and follistatin., J. Biol. Chem., 273, 7375-7381, 1998.07.
62. Futami, T., Hatanaka, Y., Matsushita, K., and Furuya, S., Expression of substance P receptor in the substantia nigra., Mol. Brain Res., 54, 183-198, 1998.03.
63. Zhang, G., Ji, L., Kurono, S., Fujita, S.C., Furuya, S., and Hirabayashi, Y., Developmentally regulated O-acetylated sialoglycans in the central nervous system Revealed by a new monoclonal antibody 493D4 recognizing a wide range of O-acetylated glycoconjugates., Glycoconjugate J., 14, 847-857, 1997.08.
64. Furuya, S., Kurono, S., and Hirabayashi, Y., Lysosphingomyelin-elicited Ca2+ release from rat brain microsomes., J. Lipid Mediat. Cell Signal., 14, 303-311, 1996.06.
65. Furuya, S., Hashikawa, T., and Hirabayashi, Y., Restricted occurrence of an unusual ganglioside GD1α in rat brain and its possible involvement in dendritic growth of cerebellar Purkinje neurons., J. Neurosci. Res., 44, 73-83, 1996.11.