Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Sumiko Watanabe Last modified date:2022.06.27

Lecturer / Medical Technology Course / Department of Health Sciences / Faculty of Medical Sciences

1. Akimasa Urakami, Hidetaka Arimura, Yukihisa Takayama, Fumio Kinoshita, Kenta Ninomiya, Kenjiro Imada, Sumiko Watanabe, Akihiro Nishie, Yoshinao Oda, Kousei Ishigami, , Stratification of prostate cancer patients into low- and high-grade groups using multiparametric magnetic resonance radiomics with dynamic contrast-enhanced image joint histograms, The Prostate, 2021.12.
2. 渡邊壽美子, 加来恒壽, 西村和徳, 植村瑞紀, 上原俊貴, 杉島節夫, 加藤聖子, 小田義直,, 岩坂剛:, 子宮頸部腺系病変における細胞像の数量的解析-AGCに注目して-, 日本臨床細胞学会九州連合会雑誌, 2021.08.
3. Hossain A, Arimura H, Kinoshita F, Ninomiya K, Watanabe S, Imada K, Koyanagi R, Oda Y., Automated Approach for Estimation of Grade Groups for Prostate Cancer based on Histological Image Feature Analysis., Prostate., 10.1002/pros.23943.[Epub ahead of print], 2019.12.
4. Sumiko Watanabe, Shota Yamaguchi, Naoto Fujii, Natsuki Eguchi, Hitoshi Katsuta, Setsuo Sugishima, Tsuyoshi Iwasaka, Tsunehisa Kaku:, Nuclear Co-expression of p21 and p27 Induced Effective Cell-cycle Arrest in T24 Cells Treated with BCG., Cytotechnology, 10.1007/s10616-018-0278-5, 2018.09.
5. Nishimura K, Watanabe S, Kato K, Sugishima S., Serum starvation induces abnormal spindle location, RhoA delocalization, and extension of intercellular bridge with the midbody., Biosci Biotechnol Biochem., 10.1080/09168451.2018.1443791., 2018.03.
6. Toomine Y, Watanabe S, Sugishima S, Ohishi Y, Tamiya S, Kobayashi H, Sonoda K, Oda Y, Kato K, Kaku T., Diagnostic Value of Squamous Cell Change Associated With Endometrial Carcinoma: A Cytopathologic Approch., Diagnostic Cytopathology, 44, 3, 187-194, 2016.11.
7. Masaki Naka, Yoshihiro Ohishi, Tsunehisa Kaku, Sumiko Watanabe, Sadafumi Tamiya, Fumihiko Ookubo, Kato K, Yoshinao Oda, Setsuo Sugishima, Identification of Intranuclear Inclusions is Useful for the Cytological Diagnosis of Ovarian Clear Cell Carcinoma, Cytotechnology, 43, 11, 879-884, 2015.11.
8. Kazunori Nishimura, Sumiko Watanabe, Ryo Hayashida, Setsuo Sugishima, Tsuyoshi Iwasaka, Tsunehisa Kaku, Binucleated HeLa cells are formed by cytokinesis failure in starvation and keep the potential of proliferation, Cytotechnology, 10.1007/s10616-015-9869-6, 2015.04, Many cytological studies have reported
that the numbers of binucleated cells were elevated in
various tumors. However, binucleated cells are observed
in not only malignant tumors but also normal
tissues. Thus, the clinical significance of binucleated
cells is controversial. Here we attempted to elucidate
the characteristics of binucleated HeLa cells using
time-lapse microscopy. To examine the frequency,
viability, proliferation, and formation mechanism of
binucleated cells, we grew HeLa cells on chamber
slides and tissue culture dishes in DMEM supplemented
with (10, 3, 1 and 0.5 % media) and without
fetal bovine serum (0 % medium). The proliferation
was evaluated by the medium improvement examination
(cultured for 2 more days in 10% medium after
culturing in 0% medium; starvation). In the 0 %
medium, 150 binucleated cells were formed by
cytokinesis failure. There were significantly more
binucleated cells in the 0 % medium than in the 10, 3,
1 and 0.5 % media. About twice the number of
binucleated cells underwent mitosis in the improvement
examinations than in the serum-free examination.
We found here that starvation induced the
binucleation of HeLa cells and that some binucleated
cells can reproduce. These findings might be helpful
for understanding binucleated cells in tumors..
9. NAOKI FUJIYOSHI, KIMIO USHIJIMA, KOUICHIRO KAWANO, KEIZO FUJIYOSHI, TOMOHIKO YAMAGUCHI3, YUKO ARAKI, TATSUYUKI KAKUMA, Sumiko Watanabe, Tsunehisa Kaku, TAKASHI NISHIDA, TOSHIHARU KAMURA, Radiation effects on DNA content of cervical cancer cells: A rapid evaluation of radiation sensitivity by laser scanning cytometry , MOLECULAR AND CLINICAL ONCOLOGY, 10.3892/mco.2014.413, 51-54, 2015.03, Abstract. Since uterine cervical cancer is regarded as a radiosensive
tumor, ionizing radiation is the most frequently used
treatment modality against the disease. Although the crucial
end-point is radiation-induced cell death, the tumors are not
equally sensitive to radiation. Determining the criteria that
may be used to predict tumor radiosensitivity is of importance;
however, little success has been achieved thus far. In radioresistant
cases the therapeutic strategy should be changed, thereby
avoiding ineffective or unnecessary treatment. Furthermore,
10. Yukie Toomine, Sumiko Watanabe, Yoshihiro Ohishi, Sadafumi Tamiya, Setsuo Sugishima, Hiroaki Kobayashi, Yoshinao Oda, Tsunehisa Kaku, Endometrial metaplasia: correlation of histological and cytological specimens obtained from 103 cases undergoing hysterectomy for endometrial carcinoma, Cytopathology, DOI:10.1111/cyt.12055, 25, 2, 78-85, 2013.04.
11. Ryotaro Jingu, Masafumi Ohki, Sumiko Watanabe,Sadafumi Tamiya, Setsuo Sugishima, Tsunehisa Kaku, Quantitative image analysis of nuclear chromatin distribution for cytological diagnosis, Acta cytologica, 330672, 2011.09.
12. Micropapillary variant of urotherial carcinoma of the urinary bladder-a case report-.
13. Cytological diagnosis of endometrial hyperplasia-Trials for the distinction of endometrial hyperplasias.
14. Noguchi M, Yokoyama M, Watanabe S, Uchiyama M, Nakao Y, Hara K, Iwasaka T, Inhibitory effect of the tea polypfenol, (-)-epigallocatechin gallate, on growth of cervical adenocarcinoma cell line, Cancer Lett., 28;234:135-42, 2006.05.
15. T.Kaku, Y.Kawano, T.Hirakawa, Y.Koga, H.Kobayashi, S.Amada, S.Ogawa, T.Hagiwara, S. Watanabe, H.Nakano, Cytological study of early cervical adenocarcinoma : special reference to the depth of invasion, Cytopatholoy, 10.1111/j.1365-2303.2005.00272.x, 16, 6, 290-294, in press, 2005.01.
16. 渡辺寿美子、岩坂剛、横山正俊、内山倫子、加来恒寿、松山敏剛, Analysis of Nuclear Chromatin Distribution in Cervical Glandular Abnormalities, Acta Cytologica, Vol.48 No.4, July-August 2004, 2004.07.
17. Significance of Nuclepli in cervical glandular cells.