Kyushu University Academic Staff Educational and Research Activities Database
List of Presentations
Atsushi SUZUKI Last modified date:2021.06.29

Professor / Department of Molecular and Cellular Biology / Medical Institute of Bioregulation


Presentations
1. Atsushi SUZUKI, Direct reprogramming to hepatic and intestinal lineages, The 18th Stem Cell Research Symposium, 2021.05.
2. Shizuka Miura, Kenichi Horisawa, Atsushi SUZUKI, Generation of mouse and human intestinal progenitor cells using direct reprogramming technology, Exchange Program Seminar between France and Japan, Frontiers of stem cell and organoid technology, From Basic to Bedside, 2021.01.
3. Atsushi SUZUKI, Generation of expandable and bipotential human hepatic progenitor cells by direct lineage reprogramming, The 5th Symposium of the Inter-University Research Network for Trans-Omics Medicine “The Future of Trans-Omics in the Age of COVID-19”, 2021.01.
4. Atsushi SUZUKI, Generation of expandable and bipotential human hepatic progenitor cells by direct lineage reprogramming, 第43回日本分子生物学会年会, 2020.12.
5. Atsushi SUZUKI, Generation of induced intestinal stem and progenitor cells by direct lineage reprogramming, The Copenhagen Bioscience Conference on Intestinal Organoids - from stem cells to metabolism and microbiome interactions, 2019.09, Under normal physiological conditions, the fates of cells that compose various parts of organs are determined during development and never change to those of other cell types. However, recent advances in the induction of cellular reprogramming provide a great chance for generation of a completely different cell type from an original cell source by artificially modulating the gene expression pattern of cells. For example, hepatocytes normally only reside in the liver. However, we have succeeded in the induction of the hepatic program in mouse fibroblasts by expressing a set of defined transcription factors. These induced hepatocyte-like cells (iHepCs) have hepatocyte-specific properties and functionally restore damaged hepatic tissues after transplantation. In a recent study, we also found a specific combination of transcription factors that can directly induce conversion of mouse fibroblasts to organoid-forming fetal intestinal progenitor cells (FIPCs), which are designated induced FIPCs (iFIPCs). Under three-dimensional culture conditions, iFIPCs give rise to cells with intestinal stem cell properties, which can produce all intestinal epithelial cell lineages and be maintained with self-renewing cell divisions, and functionally reconstitute injured colonic tissues after transplantation. Moreover, the same set of transcription factors can be used for the generation of human iFIPCs. Thus, the direct reprogramming technology that enables the production of induced intestinal organoids may provide insights into potential therapies and drug discovery research for intestinal diseases..
6. Atsushi SUZUKI, Direct reprogramming to hepatic and intestinal lineages, International Symposium: Principles of pluripotent stem cells underlying plant vitality, 2019.05.
7. Atsushi SUZUKI, Direct reprogramming to hepatic and intestinal lineages, International Symposium on Epigenome 2019, 2019.02.
8. 鈴木 淳史, Direct reprogramming to hepatic and intestinal lineages, 第41回日本分子生物学会年会, 2018.11.
9. Atsushi SUZUKI, Direct reprogramming to hepatic and intestinal lineages, 2018 The 14th Annual Meeting of TSSCR: From Pluripotency to 3D Organoid and Personalized Medicine, 2018.10.
10. Atsushi SUZUKI, Direct reprogramming to hepatic and intestinal lineages, The 27th Hot Spring Harbor International Symposium “Frontiers in Stem Cell Research and Reprogramming”, 2017.10.
11. 鈴木 淳史, Stem cell behavior in liver regeneration and diseases, 第39回日本分子生物学会年会, 2016.12.
12. Atsushi SUZUKI, Regulation of stem cell properties in liver development, The 14th Stem Cell Research Symposium, 2016.05.
13. Atsushi SUZUKI, Stem cell systems in the liver, Keystone Symposia “Stem Cells and Regeneration in the Digestive Organs”, 2016.03.
14. Shizuka MIURA, Atsushi SUZUKI, Overexpression of transcription factor Snail induces liver tumor formation, Keystone Symposia “Stem Cells and Regeneration in the Digestive Organs”, 2016.03.
15. Atsushi SUZUKI, A challenge to medical innovation from biological aspects, Tsukuba Global Science Week 2015, 2015.09.
16. Atsushi SUZUKI, Generation of functional hepatocyte-like cells by direct reprogramming technology, The Second International Meeting for Epithelial Tubulology, 2015.08.
17. 鈴木 淳史, Genetic cell lineage tracing in liver regeneration and cancer, 2014 International Symposium of Materials on Regenerative Medicine (2014 ISOMRM), 2014.08.
18. 鈴木 淳史, Direct reprogramming of fibroblasts to hepatocyte-like cells, THE UEHARA MEMORIAL FOUNDATION SYMPOSIUM 2014 Innovative Medicine : Basic Research and Development, 2014.06.
19. 高島 康郎, 寺田 茉衣子, 鈴木 淳史, The Lin28/let-7 axis regulates proliferation of hepatoblasts, 第12回幹細胞シンポジウム, 2014.05.
20. 寺田 茉衣子, 関谷 明香, 鈴木 淳史, Generation of a mouse model capable of visualizing pluripotent cells in Nanog-expressing cells, 第12回幹細胞シンポジウム, 2014.05.
21. 鈴木 淳史, Regulation of stem cell properties in liver development, 47th Annual Meeting of JSDB(第47回日本発生生物学会大会), 2014.05.
22. Atsushi SUZUKI, Artificial induction and disease-related conversion of the hepatic fate, Kyushu University / Academia Sinica Bilateral Mini-Symposium on Cancer and Stem Cell, 2014.01.
23. Atsushi SUZUKI, Artificial induction and disease-related conversion of the hepatic fate, The 7th International Conference on Cell Therapy, 2013.10.
24. Atsushi SUZUKI, Artificial induction and disease-related conversion of the hepatic fate, CSHA/ISSCR Joint Meeting on Stem Cells in Science and Medicine, 2013.10.
25. Shizuka MIURA, Atsushi SUZUKI, Analysis of hepatic lipid metabolism using iHep cells, The 20th Annual Meeting of the Japanese Society of the Research of Hepatic Cells (JSRH), 2013.09.
26. Yasuo TAKASHIMA, Masuyo KAWABATA, Atsushi SUZUKI, Analysis of intrahepatic bile ducts using a high-resolution 3D imaging system, The 20th Annual Meeting of the Japanese Society of the Research of Hepatic Cells (JSRH), 2013.09.
27. 鈴木 淳史, Prospective isolation and in vivo genetic lineage tracing of hepatic oval cells, 第86回日本生化学会大会, 2013.09.
28. 鈴木 淳史, Direct reprogramming of fibroblasts to hepatocyte-like cells, 第8回研究所ネットワーク国際シンポジウム, 2013.06.
29. Atsushi SUZUKI, Direct reprogramming of mouse fibroblasts to hepatocyte-like cells, The First International Meeting for Epithelial Tubulology, 2013.06.
30. Atsushi SUZUKI, Direct reprogramming of fibroblasts to hepatocyte-like cells, 23rd Conference of the Asia Pacific Association for the study of the Liver (APASL Liver Week 2013), 2013.06.
31. Atsushi SUZUKI, Directed cell fate reprogramming of mouse fibroblasts to hepatocyte-like cells, ISSCR-Roddenberry International Symposium on Cellular Reprogramming, 2012.10.
32. Atsushi SUZUKI, Directed cell fate reprogramming of mouse fibroblasts to hepatocyte-like cells, Asia-Pacific Developmental Biology Conference 2012, 2012.10.
33. Atsushi SUZUKI, Directed cell fate reprogramming of mouse fibroblasts to hepatocyte-like cells, 第33回日本炎症・再生医学会(International Symposium), 2012.07.