|Ochiai Masayuki||Last modified date：2022.04.06|
Post-doctoral Fellow / Pediatrics /
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|Ochiai Masayuki||Last modified date：2022.04.06|
|1.||Ochiai M、Ichiyama M、Ishimura M、Hotta T、Uchiumi T、Ishiguro A、Nishikubo T、Shima M、Suenobu T、Osamu O、Kang D、Ohga S, Next-generation diagnostic strategy for pediatric-onset heritable thrombophilia in Japan, The 8th East Asia Hemophilia Forum, 2019.02.|
|2.||Ochiai M, Invited Science Session; Extremely Prematurity Outcomes: Survival and Neurodevelopment Survival and neurodevelopmental outcome of extremely low birth weight infants, Annual Meeting of the Pediatric Academic Societies 2018, 2018.02.|
|3.||落合 正行, An Elevation of Serum Ferritin Level Might Increase Clinical Risk for the Persistence of Patent Ductus Arteriosus, Sepsis, and Bronchopulmonary Dysplasia in Erythropoietin-Treated Very Low Birth Weight Infants, Asian Society for Pediatric Research, 2017.11.|
|4.||落合 正行, Hyperferritinemia as a clinical risk factor of sepsis or bronchopulmonary dysplasia in very low birth weight infants, THE NEONATE, an International Symposium for Asia, 2017.03.|
|5.||落合 正行, Blood Reference Intervals for Preterm Low Birth Weight Infants: Multicenter Cohort Study in Japan, THE NEONATE, an International Symposium for Asia, 2017.03.|
|6.||落合 正行, Survival and neurodevelopmental outcome of preterm infants born at 22-24 weeks of gestational age, The 25th Fukuoka International Symposium on Perinatal/Maternal Medicine, 2014.08.|
|7.||市山 正子, 落合 正行, Genetic Screening of Protein C, Protein S and Antithrombin Defficiency in Pediatric Thromboembolism., PAS and ASPR Joint Meeting 2014 May 3-6, 2014 Vancouver, 2014.05.|
|8.||落合 正行, Blood chemistry and hematology reference intervals in preterm or low birth weight infants at birth, PAS and ASPR Joint Meeting 2014 May 3-6, 2014 Vancouver, 2014.05.|
|9.||落合 正行, Survival and neurodevelopmental outcome of preterm infants born at 22-24 weeks of gestational age, ASPR-PSM 2013, 2013.05, Objective: To establish the best practice for perinatal management, clinical outcomes of extremely preterm infants born at the limit of viability were studied in a tertiary center.
Study design: A retrospective study enrolled 51 infants who had no congenital disorders, and were born at 22-24 weeks of gestational age (GA) in 2000-2009 in our single institution. Clinical variables and interventions were studied with regard to one-year survival and developmental quotient (DQ) at 3 years of age.
Results: The one-year survival rate of 24 preterm infants born in 2005-2009 (79%) was higher than that of 27 those in 2000-2004 (52%) (p=0.04). The infants born at post-2005 underwent less and more frequently tocolysis (54% vs. 94%, p<0.01) and antenatal steroid therapy (32% vs. 6%, p=0.01) than those born at pre-2005, respectively. The post-2005 survivors (n=19) received more frequently indomethacin therapy (89% vs. 50%, p=0.03) and early parenteral nutrition (95% vs. 36%, p<0.01) than the pre-2005 survivors (n=14). There were no difference in the proportion of infants who attained DQ of >50 at 3-year of age between pre-2005 (n=9) and post-2005 groups (n=10) (30% vs. 33%). Multivariate analysis indicated that extremely prematurity born at GA<24w was the sole critical factor for the development status with the DQ of >50 in survivors.
Conclusions: The perinatal care after 2005 could improve the overall survival rate, but not, neurological outcomes of preterm survivors at the limit of viability. Neurodevelopmental impairments were associated with the extremely prematurity born at GA<24w.
|10.||落合 正行, Ichiyama Masako, Correlation of ADHD or ASD symptoms and WISC-3rd in VLBWI at school age, ASPR-PSM 2013, 2013.05, Background: Follow up studies of very low birth weight infant (VLBWI) have documented the risks of autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD) increase at school age.
Objectives: This study aimed to evaluate the correlation between psychiatric symptoms and intelligent quotients (IQ) in VLBWI.
Study design: A cross sectional study recruited VLBWI born at our institute in 2001-2005. We examined seventy-seven children in ADHD-Rating Scale 4th (DuPaul, 1998), Autism Spectrum Questionnaire and Wechsler Intelligence Scale for Children (WISC-3rd) at 6-9 years of age.
Results: Male VLBWI (n=45) had significantly higher total ADHD, Inattentive (IA) and Hyperactivity-Impulsivity (HI) scales than female ones (n=32) respectively (p<0.01). Multivariate analysis revealed that Verbal Comprehension (VC) and Freedom from Distractibility (FD) of WISC-3rd were negatively correlated with ASQ (cc; -0.323, 95%CI; -0.186 to -0.006, p=0.04) and IA (cc; -0.625, 95%CI; -0.350 to -0.019, p=0.03), respectively.
Conclusions: To evaluate psychiatric symptoms of VLBWI at school age, VC and FD of WISC-3rd need to be considered for educational support in addition to IQ.