Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Ochiai Masayuki Last modified date:2020.04.03

Lecturer / Department of Perinatal and Pediatric Medicine / Pediatrics / Kyushu University Hospital


Papers
1. 市山 正子, 落合 正行, Fetal hydrocephalus and neonatal stroke as the first presentation of protein C deficiency, Brain Dev, 2016.01.
2. 井上 普介, 落合 正行, Activation of Nod1 Signaling Induces Fetal Growth Restriction and Death through Fetal and Maternal Vasculopathy., J Immunol, 2016.03.
3. 落合 正行, Blood Reference Intervals for Preterm Low-Birth-Weight Infants: A Multicenter Cohort Study in Japan., PLoS One, 2016.08.
4. Masayuki Ochiai, BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector., Gene Ther., 2016.04.
5. Masayuki Ochiai, Longitudinal study of very low birth weight infants until 9years of age; attention deficit hyperactivity and autistic features are correlated with their cognitive functions., Early Hum Dev., 2015.12.
6. 山田 孝明, 落合 正行, Evaluation of teicoplanin concentrations and safety analysis in neonates, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 10.1016/j.ijantimicag.2014.07.005, 44, 5, 458-462, 2014.11.
7. Masayuki Ochiai, Survival and Neurodevelopmental Outcome of Preterm Infants Born at 22-24 Weeks of Gestational Age, NEONATOLOGY, 10.1159/000355818, 105, 2, 79-84, 2013.11, Background: The limits of viability in extremely premature infants are challenging for any neonatologists in developed countries. On the other hand, tThe neurological development and growth of extremely preterm infants have come to be the emerging issue in the next stage of following the management of in NICU.
Objective: To assess potential associations between changes in practice and survival/neurodevelopmental outcome, and clinical outcomes of extremely preterm infants born at the limit of viability were studied in a tertiary center.  
Study design: A retrospective study enrolled 51 infants who had no congenital disorders, and were born at 22-24 weeks of gestational age (GA) in 2000-2009 in our single institution. Clinical variables and interventions were studied with regard to one-year survival and developmental quotient (DQ) at 3 years of age.  
Results: The one-year survival rate of 24 preterm infants born in 2005-2009 (79%) was higher than that of the 27 those infants born in 2000-2004 (52%) (p=0.04). The iInfants born at or post-2005 underwent less and more frequently tocolysis (54% vs. 94%, p<0.01) and more frequently antenatal steroid therapy (32% vs. 6%, p=0.01) than those born at pre-20045, respectively. The post-2005 survivors (n=19) received more frequently indomethacin therapy (89% vs. 50%, p=0.03) and early parenteral nutrition (95% vs. 36%, p<0.01) than the pre-20045 survivors (n=14). There were no differences in the proportion of infants who attained a DQ of >50 at 3-years of age between pre-20045 (n=9/13=69%) and post-2005 groups (n=10/17=59%) (30% vs. 33%). Multivariate analysis indicated that extremely premature birth ity born at GA<24w was the sole critical factor for the development status with the a DQ of >50 in survivors.  
Conclusions: The perinatal care after 2005 could improved the overall survival rate, but not, the neurological outcomes of preterm survivors at the limit of viability. Neurodevelopmental impairments were associated with the extremely premature birth ity born at GA<24w.
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8. KENJI IHARA, Masayuki Ochiai, Hyperinsulinemic hypoglycemia of infancy in Sotos syndrome, AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 10.1002/ajmg.a.35657, 161A, 1, 34-37, 2013.01.
9. Shouichi Ohga, Masayuki Ochiai, Paediatric presentation and outcome of congenital protein C deficiency in Japan, HAEMOPHILIA, 10.1111/hae.12097, 19, 3, 378-384, 2013.05.
10. Hirosuke Inoue, Masayuki Ochiai, Serum neutrophil gelatinase-associated lipocalin as a predictor of the development of bronchopulmonary dysplasia in preterm infants, EARLY HUMAN DEVELOPMENT, 10.1016/j.earlhumdev.2012.12.011, 89, 6, 425-429, 2013.06.
11. 諸隈 誠一, 落合 正行, 和氣 徳夫, Ultrasound evaluation of fetal brain dysfunction based on behavioral patterns, BRAIN & DEVELOPMENT, 10.1016/j.braindev.2012.01.007, 35, 1, 61-67, 2013.01.
12. 北島 順子, 落合 正行, 原 寿郎, Differential Transmission and Postnatal Outcomes in Triplets with Intrauterine Cytomegalovirus Infection, PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, 10.2350/11-05-1034-CR.1, 15, 2, 151-155, 2012.03.
13. Kitajima J, Ohga S, Kinjo T, Ochiai M, Takahata Y, Honjo S, Hara T:, Serum prohepcidin concentrations at birth and 1 month after birth in premature infants., Pediatr Blood Cancer., 2011.02.
14. Inoue H, Ihara K, Ochiai M, Takahata Y, Kohno H, Hara T:, Congenital multiple pituitary hormone deficiency associated with hyperammonemia: a case report with a short review of the literature., J Perinatol., 2011.02.
15. Kitajima J, Inoue H, Ohga S, Kinjo T, Ochiai M, Yoshida T, Kusuhara K, Hara T:, Differential transmission and postnatal outcomes in triplets with intrauterine cytomegalovirus infection., Pediatr Dev Pathol., 2011.10.
16. Li X, Morokuma S, Fukushima K, Otera Y, Yumoto Y, Tsukimori K, Ochiai M, Hara T, Wake N:, Prognosis and long-term neurodevelopmental outcome in conservatively treated twin-to-twin transfusion syndrome., BMC Pregnancy Childbirth. , 2011.04.
17. Fukushima K, Morokuma S, Fujita Y, Tsukimori K, Satoh S, Ochiai M, Hara T, Taguchi T, Wake N:, Short-term and long-term outcomes of 214 cases of non-immune hydrops fetalis., Early Hum Dev., 87, 8, 571-575, 2011.05.
18. Kusuda T, Hikino S, Ohga S, Kinjo T, Ochiai M, Takahata Y, Tokunaga S, Ihara K, Hata Y, Hara T:, Genetic variation of vascular endothelial growth factor pathway dose not correlate with the severity of retinopathy of prematurity., J Perinatol, 31, 4, 246-250, 2011.05.
19. Kinjo T, Ohga S, Ochiai M, Honjo S, Tanaka T, Takahata Y, Ihara K, Hara T, Serum chemokine levels and developmental outcome in preterm infants., Early Hum Dev., 2011.01.
20. Kinjo T, Ohga S, Ochiai M, Honjo S, Tanaka T, Takahata Y, Ihara K, Hara T, Serum chemokine levels and developmental outcome in preterm infants., Early Hum Dev., 2011.01.
21. Hikino S, Ohga S, Kinjo T, Kusuda T, Ochiai M, Inoue H, Honjo S, Ihara K, Ohshima K, Hara T, Tracheal aspirate gene expression of preterm newborns developing bronchopulmonary dysplasia., Pediatr Int, 2011.11.
22. Inoue H, Ihara K, Ochiai M, Takahata Y, Kohno H, Hara T:, Congenital multiple pituitary hormone deficiency associated with hyperammonemia: A case report with a short review of the literature., Journal of perinatology, 2011.02.
23. Inoue H, Takada H, Kusuda T, Goto T, Ochiai M, Kinjo T, Muneuchi J, Takahata Y, Takahashi N, Morio T, Kosaki K, Hara T:, Successful cord blood transplantation for a CHARGE syndrome with CHD7 mutation showing DiGeorge sequence including hypoparathyroidism., Eur J Pediatr., 2010.06.
24. Kitajima J, Ohga S, Kinjo T, Ochiai M, Takahata Y, Honjo S, Hara T:, Serum prohepcidin concentrations at birth and one month after birth in premature infants., Pediatric Blood and Cancer, 2010.09.
25. Kusuda T, Hikino S, Ohga S, Kinjo T, Ochiai M, Takahata Y, Tokunaga S, Ihara K, Hata Y, Hara T:, Genetic variation of vascular endothelial growth factor pathway does not correlate with the severity of retinopathy of prematurity., J Perinatol, 2010.08.
26. Ochiai M, Hikino S, Nakayama H, Ohga S, Taguchi T, Hara T, Nonimmune hydrops fetalis due to generalized lymphatic dysplasia in an infant with Robertsonian trisomy 21., Am J Perinatol, 10.1055/s-2005-918892, 23, 1, 63-66, 23 (1): 63-66, 2005.05.
27. Ochiai M, Nakayama H, Sato K, Iida K, Hikino S, Ohga S, Tsukimori K, Wake N, Masumoto K, Taguchi T, Hara T, Head circumference and long-term outcome in small-for-gestational age infants., J Perinat Med, J Perinat Med, 2008.05.
28. Nagatomo T, Muta K, Ohga S, Ochiai M, Ohshima K, Hara T, Insulin-like growth factor-II: a novel autocrine growth factor modulating the apoptosis and maturation of umbilical cord blood erythroid progenitors., Exp Hematol, 36 (4): 401-411, 2008.05.
29. Ochiai M, Hikino S, Yabuuchi H, Nakayama H, Sato K, Ohga S, Hara T, A new scoring system for computed tomography of the chest for assessing the clinical status of bronchopulmonary dysplasia., J Pediatr, 130 (7): 2118-2119, 2008.01.