子どもの夜の光環境と概日リズムに関する研究
キーワード：子ども、睡眠、概日リズム、メラトニン、光環境
2013.04.
| 樋口 重和（ひぐち しげかず） | データ更新日：2023.11.27 |
主な研究テーマ
夜勤時の光環境が概日リズムとメラトニンに及ぼす影響に関する研究
キーワード：夜勤、光，概日リズム，メラトニン、パフォーマンス、眠気
2010.04.
キーワード：夜勤、光，概日リズム，メラトニン、パフォーマンス、眠気
2010.04.
ヒトのミラーニューロンシステムの研究
キーワード：ミラーニューロンシステム，神経科学
2008.04.
キーワード：ミラーニューロンシステム，神経科学
2008.04.
従事しているプロジェクト研究
交代制勤務者の夜勤時の光と概日リズムに関する研究
2019.04～2022.03, 代表者：樋口重和.
2019.04～2022.03, 代表者：樋口重和.
水晶体の光透過率の測定に関する研究
2018.04～2022.03, 代表者：樋口重和.
2018.04～2022.03, 代表者：樋口重和.
子どもの光感受性と睡眠・生体リズム・発達に関する研究
2015.04～2022.03, 代表者：樋口重和.
2015.04～2022.03, 代表者：樋口重和.
研究業績
主要著書
主要原著論文
| 1. | Taisuke Eto, Shingo Kitamura, Kana Nishimura, Kota Takeoka, Yuki Nishimura, Sang-il Lee, Michihiro Ohashi, Akiko Shikano, Shingo Noi, Shigekazu Higuchi, Circadian phase advances in children during camping life according to the natural light-dark cycle, Journal of Physiological Anthropology, 10.1186/s40101-022-00316-x, 41, 1, 2022.12. |
| 2. | Michihiro Ohashi, Sang-il Lee, Taisuke Eto, Nobuo Uotsu, Chie Tarumizu, Sayuri Matsuoka, Shinobu Yasuo, Shigekazu Higuchi, Intake of l-serine before bedtime prevents the delay of the circadian phase in real life, Journal of Physiological Anthropology, 10.1186/s40101-022-00306-z, 41, 1, 2022.08, Background It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid L-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of L-serine before bedtime on circadian phase in real life and whether its effect depends on the initial circadian phase. Methods The subjects were 33 healthy male and female university students and they were divided into an L-serine group (n = 16) and a placebo group (n = 17). This study was conducted in a double-blind manner in autumn and winter. After a baseline period for 1 week, the subjects took 3.0 g of L-serine or a placebo 30 min before bedtime for 2 weeks. Saliva was collected twice a week at home every hour under a dim light condition from 20:00 to 1 h after habitual bedtime. Dim light melatonin onset (DLMO) was used as an index of phase of the circadian rhythm. Results DLMO after intervention was significantly delayed compared to the baseline DLMO in the placebo group (p = 0.02) but not in the L-serine group. There was a significant difference in the amount of changes in DLMO between the two groups (p = 0.04). There were no significant changes in sleeping habits after intervention in the two groups. There were significant positive correlations between advance of DLMO and DLMO before intervention in the L-serine group (r = 0.53, p Conclusions Our findings suggest that intake of L-serine before bedtime for multiple days might attenuate the circadian phase delay in the real world and that this effect does not depend on the initial circadian phase.. |
| 3. | Shigekazu Higuchi, Yandan Lin, Jingjing Qiu, Yichi Zhang, Michihiro Ohashi, Sang-il Lee, Shingo Kitamura, Akira Yasukouchi, Is the use of high correlated color temperature light at night related to delay of sleep timing in university students? A cross-country study in Japan and China, Journal of Physiological Anthropology, 10.1186/s40101-021-00257-x, 40, 1, 7-7, 2021.12, Blue-enriched white light at night has the potential to delay the circadian rhythm in daily life. This study was conducted to determine whether the use of high correlated color temperature (CCT) light at home at night is associated with delay of sleep timing in university students. The survey was conducted in 2014–2015 in 447 university students in Japan and 327 students in China. Habitual sleep timing and type of CCT light at home were investigated by using a self-administered questionnaire. The Japanese students were significantly later than the Chinese students in bedtime, wake time, and midpoint of sleep. They were asked whether the lighting in the room where they spend most of their time at night was closer to warm color (low CCT) or daylight color (high CCT). The amount of light exposure level during daily life was measured for at least 1 week by the use of a light sensor in 60 students in each country. The percentages of participants who used high CCT lighting at night were 61.6% for Japanese students and 80.8% for Chinese students. Bedtime and sleep onset time on school days and free days were significantly later in the high CCT group than in the low CCT group in Japan. The midpoint of sleep in the high CCT group was significantly later than that in the low CCT group on free days but not on school days. On the other hand, none of the sleep measurements on school days and free days were significantly different between the high CCT and low CCT groups in China. Illuminance level of light exposure during the night was significantly higher in Japanese than in Chinese, but that in the morning was significantly higher in China than in Japan. The use of high CCT light at night is associated with delay of sleep timing in Japanese university students but not in Chinese university students. The effects of light at night on sleep timing and circadian rhythm may be complicated by other lifestyle factors depending on the country. |
| 4. | Taisuke Eto, Michihiro Ohashi, Kotaro Nagata, Nakyeong Shin, Yuki Motomura, Shigekazu Higuchi, Crystalline lens transmittance spectra and pupil sizes as factors affecting light-induced melatonin suppression in children and adults, OPHTHALMIC AND PHYSIOLOGICAL OPTICS, 10.1111/opo.12809, 2021.07. |
| 5. | Eto T,Petteri Teikari,Raymond P. Najjar,Nishimura Y,Motomura Y,Kuze M Higuchi S, A Purkinje image-based system for an assessment of the density and transmittance spectra of the human crystalline lens in vivo, scientific reports, 10.1038/s41598-020-73541-y, 2020.10, [URL], A method for rapid and objective assessment of ocular lens density and transmittance is needed for research and clinical practice. The aim of this study was to determine whether the Purkinje image-based technique can be used for objective and accurate quantification of spectral density and transmittance of ocular media (the mainly crystalline lens) in visible light. Twenty-six individuals (10 young, 9 middle-aged and 7 older individuals) participated in this study. Spectral lens density was evaluated by detecting the intensity of the IVth Purkinje image for different wavelengths. Subsequently, optical density index (ODI), the area under the curve in the lens density spectrum, was calculated and ODIs were compared with clinical lens opacification scales assessed subjectively using a slit lamp. Spectral lens transmittance was estimated from the lens density spectrum. Lens densities were higher in the short wavelength region of the visible spectrum across all age groups. ODI was highly correlated with the clinical opacification scale, while lens transmittance decreased with aging. Our results showed that spectral transmittance of the human crystalline lens can be easily estimated from optical density spectra evaluated objectively and rapidly using the Purkinje image-based technique. Our results provide clinicians and scientists with an accurate, rapid and objective technique for quantification of lens transmittance.. |
| 6. | Sang‐il Lee,Kouhei Matsumori,Kana Nishimura,Yuki Nishimura,Yuki Ikeda,Taisuke Eto,Shigekazu Higuchi, Melatonin suppression and sleepiness in children exposed to blue‐enriched white LED lighting at night, Physiological Reports, 2018.12, [URL], Light‐induced melatonin suppression in children is reported to be more sensitive to white light at night than that in adults; however, it is unclear whether it depends on spectral distribution of lighting. In this study, we investigated the effects of different color temperatures of LED lighting on children's melatonin secretion during the night. Twenty‐two healthy children (8.9 ± 2.2 years old) and 20 adults (41.7 ± 4.4 years old) participated in this study. A between‐subjects design with four combinations, including two age groups (adults and children) and the two color temperature conditions (3000 K and 6200 K), was used. The experiment was conducted for two consecutive nights. On the first night, saliva samples were collected every hour under a dim light condition ( |
| 7. | Shinobu Yasuo, Ayaka Iwamoto, Sang Il Lee, Shotaro Ochiai, Rina Hitachi, Satomi Shibata, Nobuo Uotsu, Chie Tarumizu, Sayuri Matsuoka, Mitsuhiro Furuse, Shigekazu Higuchi, L-serine enhances light-induced circadian phase resetting in mice and humans, Journal of Nutrition, 10.3945/jn.117.255380, 147, 12, 2347-2355, 2017.12, [URL], Background: The circadian clock is modulated by the timing of ingestion or food composition, but the effects of specific nutrients are poorly understood. Objective: We aimed to identify the amino acids that modulate the circadian clock and reset the light-induced circadian phase in mice and humans. Methods: Male CBA/N mice were orally administered 1 of 20 L-amino acids, and the circadian and light-induced phase shifts of wheel-running activity were analyzed. Antagonists of several neurotransmitter pathways were injected before L-serine administration, and light-induced phase shifts were analyzed. In addition, the effect of L-serine on the light-induced phase advance was investigated in healthy male students (mean ± SD age 22.2 ± 1.8 y) by using dim-light melatonin onset (DLMO) determined by saliva samples as an index of the circadian phase. Results: L-Serine administration enhanced light-induced phase shifts inmice (1.86-fold; P |
| 8. | Tokiho Akiyama, Takafumi Katsumura, Shigeki Nakagome, Sang Il Lee, Keiichiro Joh, Hidenobu Soejima, Kazuma Fujimoto, Ryosuke Kimura, Hajime Ishida, Tsunehiko Hanihara, Akira Yasukouchi, Yoko Satta, Shigekazu Higuchi, Hiroki Oota, An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression, PLoS One, 10.1371/journal.pone.0178373, 12, 6, 2017.06, [URL], Humans show various responses to the environmental stimulus in individual levels as physiological variations. However, it has been unclear if these are caused by genetic variations. In this study, we examined the association between the physiological variation of response to light-stimulus and genetic polymorphisms. We collected physiological data from 43 subjects, including light-induced melatonin suppression, and performed haplotype analyses on the clock genes, PER2 and PER3, exhibiting geographical differentiation of allele frequencies. Among the haplotypes of PER3, no significant difference in light sensitivity was found. However, three common haplotypes of PER2 accounted for more than 96% of the chromosomes in subjects, and 1 of those 3 had a significantly low-sensitive response to light-stimulus (P |
| 9. | Kazuo Isoda, Kana Sueyoshi, Yuki Ikeda, Yuki Nishimura, Ichiro Hisanaga, Stéphanie Orlic, Yeon Kyu Kim, Shigekazu Higuchi, Effect of the hand-omitted tool motion on mu rhythm suppression, Frontiers in Human Neuroscience, 10.3389/fnhum.2016.00266, 10, 2016.06, [URL], In the present study, we investigated the effect of the image of hands on mu rhythm suppression invoked by the observation of a series of tool-based actions in a goal-directed activity. The participants were 11 university students. As a source of visual stimuli to be used in the test, a video animation of the porcelain making process for museums was used. In order to elucidate the effect of hand imagery, the image of hands was omitted from the original (“hand image included”) version of the animation to prepare another (“hand image omitted”) version. The present study has demonstrated that, an individual watching an instructive animation on the porcelain making process, the image of the porcelain maker’s hands can activate the mirror neuron system (MNS). In observations of “tool included” clips, even the “hand image omitted” clip induced significant mu rhythm suppression in the right central area. These results suggest that the visual observation of a tool-based action may be able to activate the MNS even in the absence of hand imagery.. |
| 10. | Shigekazu Higuchi, Sang Il Lee, Tomoaki Kozaki, Tetsuo Harada, Ikuo Tanaka, Late circadian phase in adults and children is correlated with use of high color temperature light at home at night, Chronobiology International, 10.3109/07420528.2016.1152978, 33, 4, 448-452, 2016.04, [URL], Light is the strongest synchronizer of human circadian rhythms, and exposure to residential light at night reportedly causes a delay of circadian rhythms. The present study was conducted to investigate the association between color temperature of light at home and circadian phase of salivary melatonin in adults and children. Twenty healthy children (mean age: 9.7 year) and 17 of their parents (mean age: 41.9 years) participated in the experiment. Circadian phase assessments were made with dim light melatonin onset (DLMO). There were large individual variations in DLMO both in adults and children. The average DLMO in adults and in children were 21:50 ± 1:12 and 20:55 ± 0:44, respectively. The average illuminance and color temperature of light at eye level were 139.6 ± 82.7 lx and 3862.0 ± 965.6 K, respectively. There were significant correlations between color temperature of light and DLMO in adults (r = 0.735, p |
| 11. | Shigekazu Higuchi, Yuki Nagafuchi, Sang Il Lee, Tetsuo Harada, Influence of light at night on melatonin suppression in children, Journal of Clinical Endocrinology and Metabolism, 10.1210/jc.2014-1629, 99, 9, 3298-3303, 2014.09, [URL], Context: The sensitivity of melatonin to light suppression is expected to be higher in children because children have large pupilsandpure crystal lenses. However, melatonin suppression by light in children remains unclear. Copyright Objective: We investigated whether light-induced melatonin suppression in children is larger than that in adults. Methods: Thirty-three healthy primary school children(meanage, 9.2±1.5 y)and29 healthy adults (meanage, 41.6±4.7 y) participated intwoexperiments. In the first experiment, salivary melatonin concentrations in 13 children and 13 adults were measured at night under a dim light (Results: In experiment 1, the melatonin concentration was significantly decreased by exposure to moderately bright light in both adults and children. Melatonin suppression was significantly larger in children (88.2%; n = 5) than in adults (46.3%; n = 6; P Conclusion: We found that the percentage of melatonin suppression by light in children was almost twice that in adults, suggesting that melatonin is more sensitive to light in children than in adults at night.. |
| 12. | 樋口重和, 光の非視覚的作用と概日リズム：生理的多型性へのアプローチ, 日本生理人類学会誌, 18, 1, 39-43, 2013.03, [URL]. |
| 13. | Shigekazu Higuchi, Akiko Hida, Sei Ichi Tsujimura, Kazuo Mishima, Akira Yasukouchi, Sang Il Lee, Youhei Kinjyo, Manabu Miyahira, Melanopsin Gene Polymorphism I394T Is Associated with Pupillary Light Responses in a Dose-Dependent Manner, PLoS One, 10.1371/journal.pone.0060310, 8, 3, 2013.03, [URL], Background: Melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs) play an important role in non-image forming responses to light, such as circadian photoentrainment, light-induced melatonin suppression, and pupillary light response. Although it is known that there are some single nucleotide polymorphisms (SNPs) in the melanopsin (OPN4) gene in humans, the associations of the SNPs with non-image forming responses to light remains unclear. In the present study, we examined the associations of melanopsin gene polymorphisms with pupillary light response. Methods: Japanese university students (mean age: 21.0±1.7 years) with the genotypes of TT (n = 38), TC (n = 28) and CC (n = 7) at rs1079610 (I394T) located in the coding region participated in the present study. They were matched by age and sex ratio. Dark-adapted pupil size ( |
| 14. | 樋口重和, 光の非視覚的作用 -光環境への適応-, 日本生理人類学会誌, 16, 1, 21-26, 2011.03, [URL]. |
| 15. | Shigekazu Higuchi, Yutaka Motohashi, Keita Ishibashi, Takafumi Maeda, Influence of eye colors of Caucasians and Asians on suppression of melatonin secretion by light, American Journal of Physiology - Heart and Circulatory Physiology, 10.1152/ajpregu.00355.2006, 292, 6, 2007.06, [URL], This experiment tested effects of human eye pigmentation depending on the ethnicity on suppression of nocturnal melatonin secretion by light. Ten healthy Caucasian males with blue, green, or light brown irises (light-eyed Caucasians) and 11 Asian males with dark brown irises (dark-eyed Asians) volunteered to participate in the study. The mean ages of the light-eyed Caucasians and dark-eyed Asians were 26.4 ± 3.2 and 25.3 ± 5.7 years, respectively. The subjects were exposed to light (1,000 lux) for 2 h at night. The starting time of exposure was set to 2 h before the time of peak salivary melatonin concentration of each subject, which was determined in a preliminary experiment. Salivary melatonin concentration and pupil size were measured before exposure to light and during exposure to light. The percentage of suppression of melatonin secretion by light was calculated. The percentage of suppression of melatonin secretion 2 h after the start of light exposure was significantly larger in light-eyed Caucasians (88.9 ± 4.2%) than in dark-eyed Asians (73.4 ± 20.0%) (P |
| 16. | Shigekazu Higuchi, Yutaka Motohashi, Yang Liu, Akira Maeda, Effects of playing a computer game using a bright display on presleep physiological variables, sleep latency, slow wave sleep and REM sleep, Journal of Sleep Research, 10.1111/j.1365-2869.2005.00463.x, 14, 3, 267-273, 2005.09, [URL], Epidemiological studies have shown that playing a computer game at night delays bedtime and shortens sleeping hours, but the effects on sleep architecture and quality have remained unclear. In the present study, the effects of playing a computer game and using a bright display on nocturnal sleep were examined in a laboratory. Seven male adults (24.7 ± 5.6 years old) played exciting computer games with a bright display (game-BD) and a dark display (game-DD) and performed simple tasks with low mental load as a control condition in front of a BD (control-BD) and DD (control-DD) between 23:00 and 1:45 hours in randomized order and then went to bed at 2:00 hours and slept until 8:00 hours. Rectal temperature, electroencephalogram (EEG), heart rate and subjective sleepiness were recorded before sleep and a polysomnogram was recorded during sleep. Heart rate was significantly higher after playing games than after the control conditions, and it was also significantly higher after using the BD than after using the DD. Subjective sleepiness and relative theta power of EEG were significantly lower after playing games than after the control conditions. Sleep latency was significantly longer after playing games than after the control conditions. REM sleep was significantly shorter after the playing games than after the control conditions. No significant effects of either computer games or BD were found on slow-wave sleep. These results suggest that playing an exciting computer game affects sleep latency and REM sleep but that a bright display does not affect sleep variables.. |
主要総説, 論評, 解説, 書評, 報告書等
| 1. | 江藤太亮, 樋口重和, ipRGCの発見と概日リズム研究の発展, 日本色彩学会, 2021.01. |
| 2. | 樋口重和, 子どもの睡眠問題と光環境, 睡眠医療, 2017.12. |
| 3. | 樋口 重和, 李 相逸, 光のサーカディアンリズムとメラトニン分泌への作用の個人差, 照明学会誌，99(1)，20-24, 2015.01, [URL]. |
| 4. | 樋口重和, 光とヒトのメラトニン抑制, 日本時間生物学雑誌, 2008.05. |
主要学会発表等
学会活動
所属学会名
日本生理心理学会
日本生理人類学会
日本時間生物学会
日本睡眠学会
日本人間工学会
日本感性工学会
日本視覚学会
日本産業衛生学会
照明学会
The Society for Light Treatment and Biological Rhythms
学協会役員等への就任
2019.09, Internatinal Association of Physiological Anthropology.
2023.06～2025.06, 日本生理人類学会, 会長.
2023.04～2025.03, 日本時間生物学会, 理事.
2021.09, 日本睡眠学会 将来構想委員会, .
2019.04, 日本生理人類学会 光と生体リズム研究部会, 部会長.
2003.06, 日本生理人類学会, 評議員.
2003.04, 日本生理人類学会, 理事.
2009.04～2017.12, 日本生理人類学会 感性研究部会, 部会長.
2013.04～2018.03, 日本生理人類学会 照明研究部会, 部会長.
2007.04, 日本睡眠学会, 評議員.
2005.04, 日本時間生物学会, 評議員.
学会大会・会議・シンポジウム等における役割
2022.06.30～2022.07.01, 日本睡眠学会第47回定期学術集会, シンポジウム座長.
2021.11.20～2021.11.21, 第28回日本時間生物学会 実行委員, 企画立案・運営等, パネル司会・セッションチェア等.
2021.09.23～2021.09.24, 日本睡眠学会第46回定期学術集会, パネル司会・セッションチェア等.
2019.10.26～2019.10.27, 日本生理人類学会第80回大会, 座長（Chairmanship）.
2019.09.24～2019.09.27, The 14th International Congress of Physiological Anthropology, 実行委員.
2018.12.01～2018.12.01, 日本生理人類学会 光と生体リズム研究部会, 部会長.
2018.10.20～2018.10.21, 第25回日本時間生物学会, 座長（Chairmanship）.
2018.07.12～2018.07.14, 日本睡眠学会第43回定期学術集会, 座長（Chairmanship）.
2018.06.16～2018.06.17, 日本生理人類学会第77回大会, 大会長.
2017.10.28～2017.10.29, 第24回日本時間生物学会, 座長（Chairmanship）.
2017.08.21～2017.08.21, 日本生理人類学会 照明研究部会, 座長（Chairmanship）.
2017.06.24～2017.06.25, 日本生理人類学会第75回大会, 座長（Chairmanship）.
2016.09.22～2016.09.24, UNIST-JPA Joint Symposium 2016 on Anthropological and Physiological Research on Humans Living in Modern Society of the East Asia, 実行委員.
2015.10.27～2015.10.30, The 12th International Congress of Physiological Anthropology, 実行委員.
2015.10.27～2015.10.30, The 12th International Congress of Physiological Anthropology, 座長（Chairmanship）.
2015.03.20～2015.03.20, 日本生理人類学会 照明研究部会, 座長（Chairmanship）.
2015.03.14～2015.03.16, International Symposium on Human Adaptation to Environment and Whole-body Coordination, 実行委員.
2015.03.14～2015.03.16, International Symposium on Human Adaptation to Environment and Whole-body Coordination, 座長（Chairmanship）.
2014.11.21～2014.11.21, 応用生理人類学研究センター キックオフシンポジウム, 実行委員.
2014.11.09～2014.11.10, 第21回日本時間生物学会学術大会, 実行委員.
2014.09.04～2014.09.05, 2014年度日本生理人類学会夏期セミナー, 実行委員長.
2014.07.03～2014.07.04, 日本睡眠学会第39 回定期学術集会, 座長（Chairmanship）.
2014.06.21～2014.06.22, 日本生理人類学会第70回大会, 実行委員.
2014.06.21～2014.06.22, 日本生理人類学会第70回大会, 座長（Chairmanship）.
2014.05.15～2014.05.18, 国際人類学民族科学連合(IUAES), 座長（Chairmanship）.
2013.10.26～2013.10.27, 日本生理人類学会第69回大会, 座長（Chairmanship）.
2013.08.08～2013.08.10, 11th International Congress of Physiological Anthropology, 座長（Chairmanship）.
2013.06.08～2013.06.09, 日本生理人類学会第68回大会, 座長（Chairmanship）.
2012.06.28～2012.06.30, 日本睡眠学会第37回定期学術集会, 座長（Chairmanship）.
2012.05.12～2012.05.13, 日本生理人類学会第66回大会, 実行委員.
2011.06.11～2011.06.12, 日本生理人類学会第64回大会, 実行委員.
2011.03.03～2011.03.04, 第6回日本感性工学会春季大会, 座長（Chairmanship）.
2010.06.15～2010.06.16, 日本生理人類学会第62回大会, 座長（Chairmanship）.
2009.09.26～2009.09.27, 日本生理人類学会第61回大会, 実行委員.
2009.09.26～2009.09.27, 日本生理人類学会第61回大会, 座長（Chairmanship）.
2008.10.18～2008.10.19, 日本生理人類学会第59回大会, 実行委員長.
2008.06.07～2008.06.08, 日本生理人類学会第58回大会, 座長（Chairmanship）.
学会誌・雑誌・著書の編集への参加状況
2003.04～2019.12, 日本生理人類学雑誌, 国内, 編集委員.
2005.04, Journal of PHYSIOLOGICAL ANTHROPOLOGY, 国際, 編集委員.
学術論文等の審査
| 年度 | 外国語雑誌査読論文数 | 日本語雑誌査読論文数 | 国際会議録査読論文数 | 国内会議録査読論文数 | 合計 |
|---|---|---|---|---|---|
| 2022年度 | 15 | 0 | 15 | ||
| 2021年度 | 5 | 0 | 5 | ||
| 2020年度 | 8 | 0 | 8 | ||
| 2019年度 | 5 | 1 | 6 | ||
| 2018年度 | 6 | 1 | 7 | ||
| 2017年度 | 8 | 1 | 9 | ||
| 2016年度 | 4 | 2 | 6 | ||
| 2015年度 | 8 | 3 | 11 | ||
| 2014年度 | 8 | 4 | 12 | ||
| 2013年度 | 4 | 3 | 7 | ||
| 2012年度 | 5 | 3 | 8 | ||
| 2011年度 | 3 | 3 | 10 | 16 | |
| 2010年度 | 3 | 2 | 5 | ||
| 2009年度 | 4 | 1 | 5 | ||
| 2008年度 | 7 | 3 | 10 |
その他の研究活動
海外渡航状況, 海外での教育研究歴
National University of Singapore, Singapore, 2019.03～2019.03.
National University of Singapore, Singapore, 2019.09～2019.09.
Stem-cell and Brain Research Institute, France, 2019.08～2019.08.
National University of Singapore, Singapore, 2018.03～2018.03.
University of Basel , Switzerland, 2018.09～2018.09.
Loughborough University, UnitedKingdom, 2017.09～2017.09.
カリフォルニア大学サンディエゴ校（UCSD）, UnitedStatesofAmerica, 2006.02～2006.03.
受賞
日本生理人類学会 論文奨励賞, 日本生理人類学会, 2023.03.
日本生理人類学会第83回大会 優秀発表賞, 日本生理人類学会, 2023.01.
日本生理人類学会第83回大会 優秀発表賞, 日本生理人類学会, 2023.01.
日本生理人類学会 論文奨励賞, 日本生理人類学会, 2022.03.
第28回日本時間生物学会学術大会 優秀ポスター賞, 日本時間生物学会, 2021.11.
日本生理人類学会第81回大会 優秀発表賞, 日本生理人類学会, 2021.03.
日本生理人類学会第81回大会 優秀発表賞, 日本生理人類学会, 2021.03.
日本生理人類学会第80回大会 優秀発表賞, 日本生理人類学会, 2020.03.
日本生理人類学会奨励賞, 日本生理人類学会, 2020.03.
The 14th International Congress of Physiological Anthropology Best Poster Award (1st Prize), The 14th International Congress of Physiological Anthropology, 2019.09.
日本生理人類学会奨励賞, 日本生理人類学会, 2019.03.
第25回日本時間生物学会学術大会 優秀ポスター賞, 第25回日本時間生物学会学術大会, 2018.10.
日本生理人類学会第77回大会, 日本生理人類学会, 2018.06.
日本生理人類学会 優秀研究賞, 日本生理人類学会, 2015.05.
日本生理人類学会奨励賞, 日本生理人類学会, 2014.06.
国立精神神経センター精神保健研究所 青申賞, 2009.03.
日本時間生物学会 学術奨励賞, 2007.11.
日本生理人類学会 奨励賞, 1997.06.
研究資金
科学研究費補助金の採択状況(文部科学省、日本学術振興会)
2019年度～2021年度, 基盤研究(B), 代表, メラトニン受容体の遺伝子多型と夜勤時の光の生体影響.
2020年度～2024年度, 基盤研究(A), 分担, 網膜メラノプシン細胞による生体への影響の解明：心理学・生物学・工学の手法を用いて.
2020年度～2022年度, 基盤研究(B), 分担, 睡眠教育プログラムの教育現場における実証研究.
2017年度～2021年度, 基盤研究(B), 分担, 子どものメラトニン分泌パタン改善に直結するシンプル・ストラテジーの提案と実践検証.
2017年度～2019年度, 挑戦的研究（萌芽）, 代表, 子どもの高い光感受性と概日リズムを考慮した夜の光環境の指針開発に向けた研究.
2015年度～2018年度, 基盤研究(A), 代表, 子どもの高い光感受性と概日リズムの夜型化・成熟に関する研究.
2013年度～2016年度, 基盤研究(A), 分担, 高齢者向けロコモ対策用ゲームの開発を通したゲームデザイン研究 .
2012年度～2016年度, 基盤研究(A), 分担, ゲノム情報・生理的多型性・行動からみた光環境における遺伝的及び可塑的適応性の評価.
2012年度～2013年度, 挑戦的萌芽研究, 代表, 光の生理心理作用におけるプラセボ効果の検証.
2012年度～2014年度, 基盤研究(B), 代表, ヒトのメラノプシン遺伝子多型と生理機能:機能的潜在性の発現と環境適応能.
2010年度～2012年度, 基盤研究(B), 分担, 子どもの睡眠健康増進のための生理人類学的介入研究.
2010年度～2011年度, 挑戦的萌芽研究, 代表, ヒト網膜のメラノプシンの遺伝子多型およびその機能的役割の解明.
2009年度～2011年度, 基盤研究(B), 代表, 光の生理心理作用の脳内機序と健康リスクへの適応.
2008年度～2011年度, 基盤研究(A), 分担, 現代の生活環境における行動履歴が生理的多型性に及ぼす影響、及びその適応性評価.
2006年度～2008年度, 基盤研究(B), 代表, 光に対する視覚的及び非視覚的な生体反応の生理的協関性と多型性.
2004年度～2004年度, 萌芽研究, 代表, 日照量の少ない東北地方における冬季の積雪が生体リズムの同調機構に果たす役割.
2003年度～2003年度, 萌芽研究, 代表, 虹彩の色の多型が光に対する生体リズム同調に果たす役割の生理的解明にむけた基礎研究.
2003年度～2003年度, 基盤研究(C), 代表, 海外における生理人類学の研究拠点の拡大にむけた企画調査.
2003年度～2007年度, 基盤研究(S), 分担, 光と温熱の環境要因に対する生理的多型性とその適応能力.
2001年度～2002年度, 奨励研究(A), 代表, IT社会の進展と生活習慣の夜型化が睡眠，生体リズム，精神的健康度に及ぼす影響.
1998年度～1999年度, 奨励研究(A), 代表, 照明の照度・色温度条件が知的作業能率及び覚醒水準の日内リズムに及ぼす影響.
共同研究、受託研究(競争的資金を除く)の受入状況
2017.01～2019.03, 代表, 有機ＥＬディスプレイを対象とした感性・脳科学的アプローチに関する共同研究.
2013.10～2018.09, 代表, 概日時計に及ぼすL-セリンの影響に関する研究.
2017.06～2018.02, 代表, 特異作業実施場所における照明環境改善研究（その５）.
2016.12～2017.03, 代表, 特異作業実施場所における照明環境改善研究（その４）.
2009.09～2015.03, 代表, 美術館展示に関する感性・脳科学的アプローチに関する研究.
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