Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Tomokazu HATA Last modified date:2023.11.22

Assistant Professor / Psychosomatic medicine / Psychosomatic Medicine / Kyushu University Hospital


Papers
1. Yamashita M, Kawai K, Toda K, Aso C, Suematsu T, Yokoyama H, Hata T, Takakura S, Sudo N, Cardiopulmonary exercise testing for patients with anorexia nervosa: a case-control study, Eat Weight Disord, 27, 8, 3553-3560, 2022.12.
2. Takakura S, Toda K, Yamashita M, Kitajima T, Suematsu T, Yokoyama H, Asou CS, Hata T, Sudo N., Potential impact of the COVID-19 pandemic on Japanese patients with eating disorders -a cross-sectional study, BioPsychoSocial Medicine, 10.1186/s13030-021-00232-z, 16, 1, 2022.01.
3. Maiko Hiraide, Takeshi Horie, Shu Takakura, Tomokazu Hata, Nobuyuki Sudo, Kazuhiro Yoshiuchi, Correction to: Psychometric properties of the fear of food measure in Japanese women., Eating and weight disorders : EWD, 10.1007/s40519-021-01108-5, 26, 7, 2427-2428, 2021.10.
4. Maiko Hiraide, Takeshi Horie, Shu Takakura, Tomokazu Hata, Nobuyuki Sudo, Kazuhiro Yoshiuchi, Psychometric properties of the fear of food measure in Japanese women., Eating and weight disorders : EWD, 10.1007/s40519-020-01061-9, 26, 7, 2135-2142, 2021.10, PURPOSE: The aim of the present study was to investigate the psychometric properties of the fear of food measure (FOFM) in Japanese women. METHODS: This study was a cross-sectional, observational, and multicenter study conducted at the University of Tokyo and Kyushu University. Participants were comprised of 169 healthy women and 149 patients with eating disorders. First, the present study explored the factor structure of FOFM in Japanese women using exploratory factor analyses. Then, the Cronbach's alpha and McDonald's omega were calculated to assess reliability. Concurrent validity was examined by calculating correlation coefficients with the Eating Attitudes Test, negative affect of Positive and Negative Affect Schedule, and Hospital Anxiety and Depression Scale. Additionally, the Wilcoxon rank-sum test was used to compare scores between the healthy control and patient group. RESULTS: The final model had four subscales. The subscales, thus, had high reliability and showed significant positive correlations with the questionnaires. The scores of subscales in the patient group were significantly higher than those in the healthy control group. CONCLUSIONS: The FOFM had a four-factor structure in Japanese women. Its reliability and validity were verified and it could be used as a tool to assess fear of food. LEVEL OF EVIDENCE: III, case-control analytic study..
5. Takeshi Horie, Maiko Hiraide, Shu Takakura, Tomokazu Hata, Nobuyuki Sudo, Kazuhiro Yoshiuchi, Development of a new Japanese version of the Clinical Impairment Assessment Questionnaire., BioPsychoSocial medicine, 10.1186/s13030-020-00194-8, 14, 19-19, 2021.10, Background: The Clinical Impairment Assessment questionnaire (CIA) is used to measure the severity of psychosocial impairment in patients with eating disorders. The purpose of the present study was to develop a new Japanese version of the CIA (CIA-J) and to evaluate its reliability and validity. Methods: We translated the sixteen items of the CIA into Japanese, back-translated them into English, and had them verified by a native English speaking professional editor. Participants were 152 Japanese-speaking patients (30.4 ± 10.6 years) under treatment for eating disorders and 173 healthy controls (29.5 ± 8.3 years). In addition to the CIA-J, the participants were asked to answer the Eating Attitudes Test (EAT26), The Positive and Negative Affect Schedule (PANAS), and the Hospital Anxiety and Depression Scale (HADS). We performed confirmatory factor analyses to evaluate the factor structure, calculated the Cronbach's alphas of the CIA-J to assess the reliability, and calculated the correlation coefficients between the CIA-J score and those of EAT26, PANAS, and HADS to assess concurrent validity. We also used a Kruskal-Wallis test followed by Steel-Dwass test to compare the scores of the subtypes of eating disorders and the healthy control group. Results: A three-factor structure was obtained, similar to the original version. The Cronbach's alphas of both the global and subscale scores of the CIA-J were high. The CIA-J had significant positive correlations with the EAT26, the negative affect subscale of the PANAS, and the HADS. The global and subscale scores for all subtypes of eating disorders were significantly higher than those of the healthy control group. Conclusions: The CIA-J was determined to be reliable and valid for assessing the severity of psychosocial impairment in patients with eating disorders..
6. Ryo Sakamoto, Yoichi Ohtake, Yuki Kataoka, Yoshinobu Matsuda, Tomokazu Hata, Jun Otonari, Akira Yamane, Hiromichi Matsuoka, Kazuhiro Yoshiuchi, Efficacy of acceptance and commitment therapy for people with type 2 diabetes: Systematic review and meta-analysis., Journal of diabetes investigation, 10.1111/jdi.13658, 2021.09, AIMS/INTRODUCTION: This systematic review and meta-analysis aimed to investigate the efficacy and safety of acceptance and commitment therapy (ACT) for people with type 2 diabetes mellitus. MATERIALS AND METHODS: Several electronic databases were examined on 16 January 2021, including PubMed, CENTRAL, PsycINFO, International Clinical Trials Registry Platform and ClinicalTrials.gov. Randomized controlled trials were included to compare ACT with usual treatment for people with type 2 diabetes reported in any language. Primary outcome measures were glycated hemoglobin, self-care ability assessed by the summary of diabetes self-care activities and all adverse events. The secondary outcome measure was acceptance assessed by the acceptance and action diabetes questionnaire. RESULTS: Of 678 publications initially identified, three trials were included in the meta-analysis. ACT resulted in a reduction in glycated hemoglobin (mean difference -0.62 points lower in the intervention group; 95% confidence interval -1.07 to -0.16; I2  = 0%; low-quality evidence). In addition, ACT increased the score of the summary of diabetes self-care activities (mean difference 8.48 points higher in the intervention group; 95% confidence interval 2.16-14.80; high-quality evidence). Adverse events were not measured in all trials. ACT increased scores of the acceptance and action diabetes questionnaire (mean difference 5.98 points higher in the intervention group; 95% confidence interval, 1.42-10.54; I2  = 43%; low-quality evidence). CONCLUSIONS: ACT might reduce glycated hemoglobin, and increase self-care ability and acceptance among people with type 2 diabetes..
7. Miki Shimizu, Keisuke Kawai, Makoto Yamashita, Masayasu Shoji, Shu Takakura, Tomokazu Hata, Megumi Nakashima, Keita Tatsushima, Kazunari Tanaka, Nobuyuki Sudo, Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study, BioPsychoSocial medicine, 14, 14, 2021.07.
8. Natsuru Watanabe, Katsunaka Mikami, Tomokazu Hata, Keitaro Kimoto, Ryo Nishino, Fumiaki Akama, Kenji Yamamoto, Nobuyuki Sudo, Yasuhiro Koga, Hideo Matsumoto, Effect of gut microbiota early in life on aggressive behavior in mice., Neuroscience research, 10.1016/j.neures.2021.01.005, 168, 95-99, 2021.07.
9. Tae Kimura-Todani, Tomokazu Hata, Noriyuki Miyata, Shu Takakura, Kazufumi Yoshihara, Xue-Ting Zhang, Yasunari Asano, Altanzul Altaisaikhan, Takamitsu Tsukahara, Nobuyuki Sudo, Corrigendum to "Dietary delivery of acetate to the colon using acylated starches as a carrier exerts anxiolytic effects in mice"., Physiology & behavior, 10.1016/j.physbeh.2020.113259, 229, 113259-113259, 2021.02.
10. Noriyuki Miyata, Tomokazu Hata, Shu Takakura, Kazufumi Yoshihara, Chihiro Morita, Katsunaka Mikami, Koji Nomoto, Kouji Miyazaki, Hirokazu Tsuji, Nobuyuki Sudo, Metabolomics profile of Japanese female patients with restricting-type anorexia nervosa., Physiology & behavior, 10.1016/j.physbeh.2020.113204, 228, 113204-113204, 2021.01.
11. Tae Kimura-Todani, Tomokazu Hata, Noriyuki Miyata, Shu Takakura, Kazufumi Yoshihara, Xue-Ting Zhang, Yasunari Asano, Altanzul Altaisaikhan, Takamitsu Tsukahara, Nobuyuki Sudo, Dietary delivery of acetate to the colon using acylated starches as a carrier exerts anxiolytic effects in mice., Physiology & behavior, 10.1016/j.physbeh.2020.113004, 223, 113004-113004, 2020.09.
12. Takeshi Horie, Maiko Hiraide, Shu Takakura, Tomokazu Hata, Nobuyuki Sudo, Kazuhiro Yoshiuchi, Development of a new Japanese version of the Clinical Impairment Assessment Questionnaire, BioPsychoSocial Medicine, 10.1186/s13030-020-00194-8, 14, 1, 1-6, 2020.08.
13. Miki Shimizu, Keisuke Kawai, Makoto Yamashita, Masayasu Shoji, Shu Takakura, Tomokazu Hata, Megumi Nakashima, Keita Tatsushima, Kazunari Tanaka, Nobuyuki Sudo, Correction to: Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study., BioPsychoSocial medicine, 10.1186/s13030-020-00192-w, 14, 18-18, 2020.08, [This corrects the article DOI: 10.1186/s13030-020-00186-8.]..
14. Shu Takakura, Chie Suzuyama Aso, Kenta Toda, Tomokazu Hata, Makoto Yamashita, Nobuyuki Sudo, Physical and psychological aspects of anorexia nervosa based on duration of illness: a cross-sectional study., BioPsychoSocial medicine, 10.1186/s13030-019-0173-0, 13, 32-32, 2019.12, Background: We evaluated physical and psychological features of patients with anorexia nervosa (AN) who differed by duration of illness. Methods: Data were obtained from 204 female patients with AN, divided into two groups based on illness duration: short-term illness duration (less than 5 years; n = 118); and long-term duration (5 years or more; n = 86). Physical parameters were measured using blood serum testing and psychological aspects were assessed using various instruments. Results: A significantly higher proportion of restricting type AN was observed in the short-term group while the proportion of binge eating/purging type AN was higher in the long-term group. There was no difference in body mass index (BMI) between the groups. Serum total protein, albumin, potassium, chloride, and calcium in the long-term group were significantly lower than in the short-term group. Overall scores on the Eating Disorder Inventory as well as most of the subscales, except maturity fears, were higher in the long-term group than in the short-term group. The care subscale of the Parental Bonding Instrument (PBI) was lower in the long-term group than in the short-term group, while the overprotection subscale of the PBI was higher in the long-term group than in the short-term group. Results of a multiple regression analysis indicated that the overprotection subscale of the PBI was the only significant predictor of duration of illness. Conclusions: Duration of illness may be associated with physical and psychological features of AN; thus, adapting therapeutic approaches to illness duration might be necessary..
15. Tomokazu Hata, Noriyuki Miyata, Shu Takakura, Kazufumi Yoshihara, Yasunari Asano, Tae Kimura-Todani, Makoto Yamashita, Xue-Ting Zhang, Natsuru Watanabe, Katsunaka Mikami, Yasuhiro Koga, Nobuyuki Sudo, The Gut Microbiome Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral Performance in Female Mice., Endocrinology, 10.1210/en.2019-00408, 160, 10, 2441-2452, 2019.10.
16. Tomokazu Hata, Yasunari Asano, Kazufumi Yoshihara, Tae Kimura-Todani, Noriyuki Miyata, Xue-Ting Zhang, Shu Takakura, Yuji Aiba, Yasuhiro Koga, Nobuyuki Sudo, Regulation of gut luminal serotonin by commensal microbiota in mice., PloS one, 10.1371/journal.pone.0180745, 12, 7, e0180745, 2017.07.
17. Sawamoto R, Nozaki T, Nishihara T, Furukawa T, Hata T, Komaki G, Sudo N, Predictors of successful long-term weight loss maintenance: a two-year follow-up, Biopsychosoc Med, 11:14, 2017.06.
18. Ryoko Sawamoto, Takehiro Nozaki, Tomoe Nishihara, Tomokazu Furukawa, Tomokazu Hata, Gen Komaki, Nobuyuki Sudo, Predictors of successful long-term weight loss maintenance: a two-year follow-up., BioPsychoSocial medicine, 10.1186/s13030-017-0099-3, 11, 14-14, 2017.06, BACKGROUND: Weight regain is a common problem following weight loss intervention, with most people who seek treatment for obesity able to lose weight, but few able to sustain the changes in behavior required to prevent subsequent weight regain. The identification of factors that predict which patients will successfully maintain weight loss or who are at risk of weight regain after weight loss intervention is necessary to improve the current weight maintenance strategies. The aim of the present study is identify factors associated with successful weight loss maintenance by women with overweight or obesity who completed group cognitive behavioral treatment (CBT) for weight loss. METHODS: Ninety women with overweight or obesity completed a 7-month weight loss intervention. The data of 86 who completed follow-up surveys 12 and 24 months after the end of the treatment was analyzed. Depression, anxiety, binge eating, food addiction, and eating behaviors were assessed before and after the weight loss intervention. Participants who lost at least 10% of their initial weight during the weight loss intervention and had maintained the loss at the month 24 follow-up were defined as successful. RESULTS: The intervention was successful for 27 participants (31.3%) and unsuccessful for 59 (68.6%). Multiple logistic regression analysis extracted larger weight reduction during the weight loss intervention, a lower disinhibition score, and a low food addiction score at the end of the weight loss intervention as associated with successful weight loss maintenance. CONCLUSION: The results suggest that larger weight reduction during the weight loss intervention and lower levels of disinhibition and food addiction at the end of the weight loss intervention predicted successful weight loss maintenance. TRIAL REGISTRATION: Trial registry name: Development and validation of effective treatments of weight loss and weight-loss maintenance using cognitive behavioral therapy for obese patients. Registration ID: UMIN000006803 Registered 1 January 2012. URL: https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000008052..
19. Sawamoto R, Nozaki T, Furukawa T, Tanahashi T, Morita C, Hata T, Nakashima M, Sudo N, A change in objective sleep duration is associated with a change in the serum adiponectin level of women with overweight or obesity undergoing weight loss intervention., Obes Sci Pract, 2(2): 180-188, 2016.06.
20. Sawamoto R, Nozaki T, Furukawa T, Tanahashi T, Morita C, Hata T, Komaki G, Sudo N, Predictors of Dropout by Female Obese Patients Treated with a Group Cognitive Behavioral Therapy to Promote Weight Loss, Obes Facts, 9(1): 29-38, 2016.01.
21. Ryoko Sawamoto, Takehiro Nozaki, Tomokazu Furukawa, Tokusei Tanahashi, Chihiro Morita, Tomokazu Hata, Gen Komaki, Nobuyuki Sudo, Predictors of Dropout by Female Obese Patients Treated with a Group Cognitive Behavioral Therapy to Promote Weight Loss., Obesity facts, 10.1159/000442761, 9, 1, 29-38, 2016.01, OBJECTIVE: To investigate predictors of dropout from a group cognitive behavioral therapy (CBT) intervention for overweight or obese women. METHODS: 119 overweight and obese Japanese women aged 25-65 years who attended an outpatient weight loss intervention were followed throughout the 7-month weight loss phase. Somatic characteristics, socioeconomic status, obesity-related diseases, diet and exercise habits, and psychological variables (depression, anxiety, self-esteem, alexithymia, parenting style, perfectionism, and eating attitude) were assessed at baseline. Significant variables, extracted by univariate statistical analysis, were then used as independent variables in a stepwise multiple logistic regression analysis with dropout as the dependent variable. RESULTS: 90 participants completed the weight loss phase, giving a dropout rate of 24.4%. The multiple logistic regression analysis demonstrated that compared to completers the dropouts had significantly stronger body shape concern, tended to not have jobs, perceived their mothers to be less caring, and were more disorganized in temperament. Of all these factors, the best predictor of dropout was shape concern. CONCLUSION: Shape concern, job condition, parenting care, and organization predicted dropout from the group CBT weight loss intervention for overweight or obese Japanese women..
22. Morita C, Tsuji H, Hata T, Gondo M, Takakura S, Kawai K, Yoshihara K, Ogata K, Nomoto K, Miyazaki K, Sudo N, Gut Dysbiosis in Patients with Anorexia Nervosa, PLoS One, 10(12): e0145274, 2015.12.
23. Shu Takakura, Yokoyama H, Suzuyama C, Tatsushima K, Yamashita M, Gondo M, Morita C, Hata T, Takii M, Kawai K, Sudo N, Three cases of appendicitis with anorexia nervosa under inpatient care, J Eat Disord, 3:38, 2015.11.
24. Sawamoto R, Nozaki T, Furukawa T, Tanahashi T, Morita C, Hata T, Komaki G, Sudo N, Higher sleep fragmentation predicts a lower magnitude of weight loss in overweight and obese women participating in a weight-loss intervention., Nutr Diabetes, e144, 2014.10.
25. Amemiya N, Takii M, Hata T, Morita C, Takakura S, Oshikiri K, Urabe H, Tokunaga S, Nozaki T, Kawai K, Sudo N, Kubo C, The outcome of Japanese anorexia nervosa patients treated with an inpatient therapy in an internal medicine unit, Eat Weight Disord, 17(1), e1-8, 2012.03.
26. Kawai K, Yamashita S, Yamanaka T, Gondo M, Morita C, Nozaki T, Takakura S, Hata T, Yamada Y, Matsubayashi S, Takii M, Kubo C, Sudo N, The longitudinal BMI pattern and body composition of patients with anorexia nervosa who require urgent hospitalization: A case control study, Biopsychosoc Med, 5, 2011.12.
27. Keisuke Kawai, Sakino Yamashita, Takeharu Yamanaka, Motoharu Gondo, Chihiro Morita, Takehiro Nozaki, Shu Takakura, Tomokazu Hata, Yu Yamada, Sunao Matsubayashi, Masato Takii, Chiharu Kubo, Nobuyuki Sudo, The longitudinal BMI pattern and body composition of patients with anorexia nervosa who require urgent hospitalization: A case control study., BioPsychoSocial medicine, 10.1186/1751-0759-5-14, 5, 14-14, 2011.12, BACKGROUND: The prevention of serious physical complications in anorexia nervosa (AN) patients is important. The purpose of this study is to clarify which physical and social factors are related to the necessity for urgent hospitalization of anorexia nervosa (AN) patients in a long-term starvation state. We hypothesized that the change of longitudinal BMI, body composition and social background would be useful as an index of the necessity for urgent hospitalization. METHODS: AN patients were classified into; urgent hospitalization, due to disturbance of consciousness or difficulty walking(n = 17); planned admission (n = 96); and outpatient treatment only groups (n = 136). The longitudinal BMI pattern and the clinical features of these groups were examined. In the hospitalization groups, comparison was done of body composition variation and the social background, including the educational level and advice from family members. RESULTS: After adjusting for age and duration of illness, the BMI of the urgent hospitalization group was lower than that of the other groups at one year before hospitalization (P
28. Takii M, Uchigata Y, Kishimoto J, Morita C, Hata T, Takehiro Nozaki, Keisuke Kawai, Iwamoto Y, Sudo N, Kubo C, The relationship between the age of onset of type 1 diabetes and the subsequent development of a severe eating disorder by female patients, Pediatr Diabetes, 12, 296-401, 2011.06.
29. Masato Takii, Yasuko Uchigata, Junji Kishimoto, Chihiro Morita, Tomokazu Hata, Takehiro Nozaki, Keisuke Kawai, Yasuhiko Iwamoto, Nobuyuki Sudo, Chiharu Kubo, The relationship between the age of onset of type 1 diabetes and the subsequent development of a severe eating disorder by female patients., Pediatric diabetes, 10.1111/j.1399-5448.2010.00708.x, 12, 4 Pt 2, 396-401, 2011.06, OBJECTIVES: To determine the age of onset of type 1 diabetes that is most closely related to the subsequent development of a severe eating disorder such as anorexia nervosa (AN) or bulimia nervosa (BN). METHODS: Participants were 53 female type 1 diabetes patients with AN or BN referred to our outpatient clinic from the Diabetes Center of Tokyo Women's Medical University. Forty-nine female type 1 diabetes patients who regularly visited the Diabetes Center and had no eating disorder-related problems constituted the 'direct control' group, whereas 941 female patients who for the first time visited the Diabetes Center constituted the 'historical control' group. The kernel function method was used to generate a density estimation of the onset age of each group and the chi-square test was used to compare the distribution. RESULTS: The control groups had similar density shapes for the onset age of type 1 diabetes, but both differed from the 'eating disorder' group. For onset age 7-18 yr, the density of the 'eating disorder' group was higher than those of the control groups, but for the younger and older onset ages the densities were lower. The 'eating disorder' group developed type 1 diabetes significantly more frequently than the 'historical control' group between 7 and 18 yr of age (χ2 = 9.066, p