Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Shinichi Mizuno Last modified date:2021.06.30

Professor / Division of Medical Sciences and Technology / Department of Health Sciences / Faculty of Medical Sciences


Papers
1. Sakimura S, Nagayama S, Fukunaga M, Hu Q, Kitagawa A, Kobayashi Y, Hasegawa T, Noda M, Kouyama Y, Shimizu D, Saito T, Niida A, Tsuruda Y, Otsu H, Matsumoto Y, Uchida H, Masuda T, Sugimachi K, Sasaki S, Yamada K, Takahashi K, Innan H, Suzuki Y, Nakamura H, Totoki Y, Mizuno S, Ohshima M, Shibata T, Mimori K., Impaired tumor immune response in metastatic tumors is a selective pressure for neutral evolution in CRC cases, PLoS Genetics, 17, e1009113, 2021.06.
2. Hasegawa T, Hayashi S, Shimizu E, Mizuno S, Niida A, Yamaguchi R, Miyano S, Nakagawa H, Imoto S., Neoantimon: a multifunctional R package for identification of tumor-specific neoantigens, Bioinformatics, 36, 4813-4816, 2021.06.
3. Nakamura T, Morishige S, Ozawa H, Kuboyama K, Yamasaki Y, Oya S, Yamaguchi M, Aoyama K, Seki R, Mouri F, Osaki K, Okamura T, Mizuno S, Nagafuji K., Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-mediated gene editing., Haemophilia, 26, 826-833, 2021.06.
4. ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Pan-cancer analysis of whole genomes., Nature, 578, 82-93, 2020.02.
5. Satoshi Morishige, Shinichi Mizuno, Hidetoshi Ozawa, Takayuki Nakamura, Ahmad Mazahery, Kei Nomura, Ritsuko Seki, Fumihiko Mouri, Koichi Osaki, Kenichi Yamamura, Takashi Okamura, Koji Nagafuji , CRISPR/Cas9-mediated Gene Correction in Hemophilia B Patient-Derived iPSCs, Int J Hematol., 10.1007/s12185-019-02765-0 , 111, 2, 225-233, 2020.02.
6. Hayashi S, Moriyama T, Yamaguchi R, Mizuno S, Komura M, Miyano S, Nakagawa H, Imoto S., ALPHLARD-NT: Bayesian Method for Human Leukocyte Antigen Genotyping and Mutation Calling through Simultaneous Analysis of Normal and Tumor Whole-Genome Sequence Data., J Comput Biol., 2019.04.
7. Nakano M, Kikushige Y, Miyawaki K, Kunisaki Y, Mizuno S, Takenaka K, Tamura S, Okumura Y, Ito M, Ariyama H, Kusaba H, Nakamura M, Maeda T, Baba E, Akashi K., Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer., Oncogene, 2019.02.
8. Hayashi S, Yamaguchi R, Mizuno S, Komura M, Miyano S, Nakagawa H, Imoto S., ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data., BMC Genomics, 2018.11.
9. Mizuno S, Iino T, Ozawa H, Arinobu Y, Chong Y, Akashi K, Notch1 expression is regulated at the post-transcriptional level by the 3' untranslated region in hematopoietic stem cell development., Int J Hematol, 107, 311-319, 2018.01.
10. Shima T, Miyamoto T, Kikushige Y, Yuda J, Tochigi T, Yoshimoto G, Kato K, Takenaka K, Iwasaki H, Mizuno S, Goto N, Akashi K, The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell. , Exp Hematol, 42, 955-65, 2014.01.
11. Morishige S, Oku E, Takata Y, Kimura Y, Arakawa F, Seki R, Imamura R, Osaki K, Hashiguchi M, Yakushiji K, Mizuno S, Yoshimoto K, Nagafuji K, Ohshima K, Okamura T, A case of 8p11 myeloproliferative syndrome with BCR-FGFR1 gene fusion presenting with trilineage acute leukemia/lymphoma, successfully treated by cord blood transplantation. , Acta Haematol, 129, 83-89, 2013.01.
12. Nakaya T, Ishiguro KI, Belzil C, Rietsch AM, Yu Q, Mizuno SI, Bronson RT, Geng Y, Nguyen MD, Akashi K, Sicinski P, Nakatani Y, p600 Plays Essential Roles in Fetal Development. , PLoS One, 8, e66269, 2013.01.
13. Int J Hematol. 96(5): 657-663, 2012, Unrelated cord blood transplantation for patients with adult T-cell leukemia/lymphoma: experience at a single institute. Int J Hematol. 96: 657-63, 2012, Int J Hematol, 96, 657-663, 2012.01.
14. Kalaszczynska I, Geng Y, Iino T, Mizuno S, Choi Y, Kondratiuk I, Silver DP, Wolgemuth DJ, Akashi K, Sicinski P, Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells., Cell, 138, 352-365, 2009.01.
15. Yoshimoto G, Miyamoto T, Jabbarzadeh-Tabrizi S, Iino T, Rocnik JL, Kikushige Y, Mori Y, Shima T, Iwasaki H, Takenaka K, Nagafuji K, Mizuno S, Niiro H, Gilliland GD, Akashi K, FLT3-ITD upregulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation., Blood, 114, 5034-5043, 2009.01.
16. Arinobu Y, Mizuno S, Chong Y, Shigematsu H, Iino T, Iwasaki H, Graf T, Mayfield R, Chan S, Kastner P, Akashi K, Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages., Cell Stem Cell, 1, 416-427, 2007.01.
17. Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, Shigematsu H, Takatsu K, Tenen DG, Akashi K, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. , Genes Dev, 20, 3010-3021, 2006.01.
18. Hirai H, Zhang P, Dayaram T, Hetherington CJ, Mizuno S, Imanishi J, Akashi K, Tenen DG, C/EBPbeta is required for 'emergency' granulopoiesis., Nature Immunology, 7, 732-739, 2006.01.
19. Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ, Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells., Science, 307, 1101-1104, 2005.01.
20. Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, Akashi K, Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med. 201: 1891-7, 2005, Proc Natl Acad Sci U S A, 102, 18105-18110, 2005.01.
21. Iwasaki H, Somoza C, Shigematsu H, Duprez EA, Iwasaki-Arai J, Mizuno S, Arinobu Y, Geary K, Zhang P, Dayaram T, Fenyus ML, Elf S, Chan S, Kastner P, Huettner CS, Murray R, Tenen DG, Akashi K, Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation., Blood, 106, 1590-1600, 2005.01.
22. Huntly BJ, Shigematsu H, Deguchi K, Lee BH, Mizuno S, Duclos N, Rowan R, Amaral S, Curley D, Williams IR, Akashi K, Gilliland DG, MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors., Cancer Cell, 6, 587-596, 2004.01.
23. Shigematsu H, Reizis B, Iwasaki H, Mizuno S, Hu D, Traver D, Leder P, Sakaguchi N, Akashi K, Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin., Immunity, 21, 43-53, 2004.01.
24. Iwasaki H, Mizuno S, Wells RA, Cantor AB, Watanabe S, Akashi K, GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages., Immunity, 19, 451-462, 2003.01.
25. Mizuno S, Chijiwa T, Okamura T, Akashi K, Fukumaki Y, Niho Y, Sasaki H, Expression of DNA methyltransferases DNMT1, 3A and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia., Blood, 91, 1172-1179, 2001.01.
26. Akashi K, Mizuno S, Epstein-Barr virus-infected natural killer cell leukemia., Leuk Lymphoma, 40, 57-66, 2000.01.
27. Mizuno S, Okamura T, Iwasaki H, Ohno Y, Akashi K, Inaba S, Niho Y, Hypercoagulable state following transfusions of granulocytes obtained from granulocyte colony- stimulating factor-stimulating donors., Int J Hematol, 72, 115-117, 2000.01.
28. Kato R, Shirohzu H, Yokomine T, Mizuno S, Mukai T, Sasaki H, Sequence-ready 1-Mb YAC, BAC and cosmid contigs covering the distal imprinting region of mouse chromosome 7. , DNA Research, 6, 401-405, 1999.01.
29. Inoue T, Yamaza H, Sakai Y, Mizuno S, Ohno M, Hamasaki N, Fukumaki Y, Position-independent human beta-globin gene expression mediated by a recombinant adeno-associated virus vector carrying the chicken beta-globin insulator., J Hum Genet, 44, 152-162, 1999.01.
30. Mizuno S, Akashi K, Ohshima K, Iwasaki H, Miyamoto T, Uchida N, Shibuya T, Harada M, Kikuchi M, Niho Y, Interferon-gamma prevents apoptosis in Epstein-Barr virus-infected natural killer cell leukemia in an autocrine fashion., Blood, 93, 3439-3540, 1999.01.
31. Takenaka K, Gondo H, Tanimoto K, Nagafuji K, FujisakiT, Mizuno S, Miyamoto T, Okamura T, Hayashi S, Eto T, Osaki K, Yamasaki K, Shibuya T, Harada N, Teshima T, Matuishi E, Minematus T, Minamishima Y, Harada M, Niho Y, Increased incidence of cytomegalovirus(CMV) infection and CMV-associated disease after allogeneic bone marrow transplantation from unrelated donors., Bone Marrw Transplant, 19, 241-248, 1997.01.
32. Miyamoto T, Inaba S, Harada M, Makino S, Teshima T, Takamatsu Y, Eto T, Nagafuji K,Mizuno S, Gondo H, Niho Y, Collection and transplantation of autologous peripheral blood stem cells in adults., Jap J Apheresis, 16, 50-55, 1997.01.
33. Harada M, Akashi K, Hayashi S, Eto T, Takamatsu Y, Teshima T, Hirota Y, Taniguchi S, Nagafuji K, Mizuno S, Gondo H, Niho Y, Granulocyte colony-stimulating factor-combined marrow-ablative chemotherapy and autologous blood cell transplantation for the treatment of patients with acute yelogenous leukemia in first remission., Int J Hematol, 66, 297-301, 1997.01.
34. Gondo H, Harada M, Miyamoto T, Takenaka K, Tanimoto K, Mizuno S, Fujisaki T, Nagafuji K, Hayashi S, Eto T, Taniguchi S, Akashi K, Harada N, Yamasaki K, Shibuya T, Matsuishi E, Ohno Y, Makino S, Takamatsu Y, Murakawa M, Teshima T, Hirota Y, Okamura T, Kinukawa N, Niho Y, Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia., Bone Marrow Transplant, 20, 821-826, 1997.01.
35. Takenaka T, Nagafuji K, Harada M, Mizuno S, Miyamoto T, Makino S, Gondo H, Okamura T, Niho Y, In vitro expansion of hematopoietic progenitor cells induces functional expression of Fas antigen(CD95). , Blood, 88, 2871-2877, 1996.01.
36. Takenaka K, Mizuno S, Harada M, Nagafuji K, Miyamoto T, Iwasaki H, Fujisaki T, Kubota A, Ohno Y, Arima F, Shigematsu H, Gondo H, Okamura T, Okamura S, Inaba S, Niho Y, Generation of human natural killer cells from peripheral blood CD34+cells mobilized by granulocyte colony-stimulating factor., Br J Haematol, 92, 788-794, 1996.01.
37. Miyamoto T, Nagafuji K, Akashi K, Harada M, Kyo T, Akashi T, Takenaka K, Mizuno S, Gondo H, Okamura T, Dohy H, Niho Y, Persistence of multipotent progenitors expressing AML1 / ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia., Blood, 87, 4789-4796, 1996.01.
38. Harada M, Nagafuji K, Fujisaki T, Kubota A, Mizuno S, Takenaka K, Miyamoto T, Ohno Y, Gondo H, Kuroiwa M, Okamura T, Inaba S, Niho Y, G-CSF-induced mobilization of peripheral blood stem cells from healthy adults for allogeneic transplantation., J Hematother, 5, 63-71, 1996.01.
39. Takenaka T, Nagafuji K, Harada M, Mizuno S, Miyamoto T, Makino S, Gondo H, Okamura T, Niho Y, In vitro expansion of hematopoietic progenitor cells induces functional expression of Fas antigen(CD95). , Blood, 88, 2871-2877, 1996.01.
40. Nagafuji K, Shibuya T, Harada M, Mizuno S, Takenaka K, Miyamoto T, Okamura T, Gondo H, Niho Y, Functional expression of Fas antigen(CD95) on hematopoietic progenitor cells., Blood, 86, 883-889, 1995.01.
41. Miyamoto T, Nagafuji K, Harad M, Yamasaki K, Shibuya T, Iwasaki H, Akashi K, Mizuno S, Eto T, Takenaka K, Gondo H, Okamura T, Niho Y, Characterization of blasts from a patient with eosinophilic blast crisis of chronic myelogenous leukaemia., Br J Haematol, 89, 207-210, 1995.01.
42. Miyamoto T, Nagafuji K, Harada M, Eto T, Fujisaki T, Kubota A, Akashi K, Mizuno S, Takenaka K, Kanaji T, Gondo H, Okamura T, Inaba S, Niho Y, Quantitative analysis of AML1 / ETO transcripts in peripheral blood stem cell harvests from patients with t(8;21) acute myelogenous leukemia., Br J Haematol, 91, 132-138, 1995.01.
43. Ohshima K, Kikuchi M, Mizuno S, Akashi K, Moriyama K, Yoneda S, Takeshita M, Shibata T, Hepatosinusoidal leukemia / lymphoma consisting of Epstein-Barr virus-containing natural killer cell leukemia / lymphoma and T-cell lymphoma; mimicking malignant histiocytosis., Hematological Oncol, 13, 83-97, 1995.01.
44. Akashi K, Mizuno S, Harada M, Kimura N, Kinjyo M, Shibuya T, Shimoda K, Takeshita M, Okamura S, Matsumoto I, Kikuchi M, Niho Y, T lymphoid / myeloid bilineal crisis in chronic myelogenous leukemia., Exp Hematol, 21, 743-748, 1993.01.
45. Mizuno S, Akashi K, Hirota Y, Gyoten S, Matsumoto I, Harada M, Niho Y, Filgrastim treatment of leukaemic transformation in myelodysplastic syndrome., Lancet, 341, 1475-1476, 1993.01.