九州大学-研究者情報 [吉田晋一郎 (助教) 九州大学病院口腔機能修復科]

吉田晋一郎（よしだしんいちろう）

データ更新日：2024.04.16

助教　／　九州大学病院口腔機能修復科九州大学大学院歯学研究院　口腔機能修復学講座　歯科保存学研究分野

総説, 論評, 解説, 書評, 報告書等

Shinichiro Yoshida, Atsushi Tomokiyo, Daigaku Hasegawa, Sayuri Hamano, Hideki Sugii, Hidefumi Maeda., Insight into the Role of Dental pulp Stem Cells in Regenerative Therapy, Biology, 2020.07, Mesenchymal stem cells (MSCs) have the capacity for self-renewal and multilineage differentiation potential, and are considered a promising cell population for cell-based therapy and tissue regeneration. MSCs are isolated from various organs including dental pulp, which originates from cranial neural crest-derived ectomesenchyme. Recently, dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth (SHEDs) have been isolated from dental pulp tissue of adult permanent teeth and deciduous teeth, respectively. Because of their MSC-like characteristics such as high growth capacity, multipotency, expression of MSC-related markers, and immunomodulatory effects, they are suggested to be an important cell source for tissue regeneration. Here, we review the features of these cells, their potential to regenerate damaged tissues, and the recently acquired understanding of their potential for clinical application in regenerative medicine..

吉田晋一郎、前田英史, 4-META/MMA-TBBレジンの直接覆髄材への応用, 日本歯内療法学会雑誌, 2019.05.

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九州大学病院


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