九州大学 研究者情報
論文一覧
土谷 享(つちや あきら) データ更新日:2021.06.25

助教 /  歯学研究院 歯学部門 口腔機能修復学講座生体材料学分野


原著論文
1. Yuta Sakemi, Koichiro Hayashi, Akira Tsuchiya, Yasuharu Nakashima, Kunio Ishikawa, Reconstruction of critical-size segmental defects in rat femurs using carbonate apatite honeycomb scaffolds, Ceramics International, 10.1002/jbm.a.37157, 2021.05.
2. Ryo Kishida, Maab Elsheikh, Koichiro Hayashi, Akira Tsuchiya, Kunio Ishikawa, Fabrication of highly interconnected porous carbonate apatite blocks based on the setting reaction of calcium sulfate hemihydrate granules, Ceramics International, 10.1016/j.ceramint.2021.03.324, 2021.04.
3. Taiga Ono, Atsuchi Tomokiyo, Keita Ipposhi, Kozue Yamashita, M Anas Alhasan, Yudai Miyazaki, Yoshihiro Kunitomi, Akira Tsuchiya, Kunio Ishikawa, Hidefumi Maeda, Generation of biohybrid implants using a multipotent human periodontal ligament cell line and bioactive core materials. Journal of Cellular Physiology, Journal of Biomedical Materials Research Part A, 2021.02.
4. Keisuke Tanaka, Akira Tsuchiya, Yoichiro Ogino, Kiyoshi Koyano, Kunio Ishikawa, Fabrication and histological evaluation of a fully interconnected porous CO3Ap block formed by hydrate expansion of CaO granules., ACS Applied Bio Materials, 2020.11.
5. Sunarso, Akira Tsuchiya, Riki Toita, Kanji Tsuru, Kunio Ishikawa, Enhanced osseointegration capability of poly(ether ether ketone) via combined phosphate and calcium surface-functionalization. International Journal of Molecular Science, International Journal of Molecular Science, 10.3390/ijms21010198s, 21, 198, 2020.03.
6. Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa, Granular honeycombs composed of carbonate apatite, hydroxyapatite, and β-tricalcium phosphate as bone graft substitutes: Effects of composition on bone formation and maturation, ACS Applied Bio Materials, 10.1021/acsabm.0c00060., 3, 1787-1795, 2020.02.
7. Yuta Sakemi, Koichiro Hayashi, Akira Tsuchiya, Yasuharu Nakashima, Kunio Ishikawa, Fabrication and histological evaluation of porous carbonate apatite block from gypsum block containing spherical phenol resin as a porogen., Materials, 10.3390/ma12233997, 12, 3997, 2019.12.
8. Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa, Honeycomb blocks composed of carbonate apatite, β-tricalcium phosphate, and hydroxyapatite for bone regeneration: effects of composition on biological responses., Materials, 10.1016/j.mtbio.2019.100031., 4, 100031, 2019.07.
9. Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, and Kunio Ishikawa, Carbonate apatite micro-honeycombed blocks generate bone marrow-like tissues as well as bone. , Advanced Biosystems, 10.1002/adbi.201900140., 3, 1900140, 2019.03.
10. Naoyuki Fukuda, Akira Tsuchiya, Sunarso, Riki Toita, Kanji Tsuru, Yoshihide Mori, Kunio Ishikawa, Surface plasma treatment and phosphorylation enhance the biological performance of poly(ether ether ketone)., Colloids and Surfaces B: Biointerfaces, 197, 36-42, 2019.01.
11. Naoyuki Fukuda, Masayuki Kanazawa, Kanji Tsuru, Akira Tsuchiya, Sunarso, Riki Toita, Yoshihide Mori, Yasuharu Nakashima, Kunio Ishikawa, Synergistic effect of surface phosphorylation and micro-roughness on enhanced osseointegration ability of poly(ether ether ketone) in the rabbit tibia., Scientific Reports, 8, 16887, 2018.11.
12. Akira Tsuchiya, Marino Sato, Ichiro Takahashi, Kunio Ishikawa, Fabrication of apatite-coated gypsum granules and histological evaluation using rabbits. Ceramics International., Ceramics International, 11, 20330-20336, 2018.11.
13. Eddy, Akira Tsuchiya, Kanji Tsuru, Kunio Ishikawa, Fabrication of self-setting β-TCP granular cement using β-TCP granules and sodium hydrogen sulfate solution., Journal of Biomaterials Applications, 33, 630-636, 2018.10.
14. Kunio Ishikawa, Youji Miyamoto, Akira Tsuchiya, Koichiro Hayashi, Kanji Tsuru, Go Ohe, Physical and histological comparison of hydroxyapatite, carbonate apatite, and β-tricalcium phosphate bone substitutes., Materials, 11, 1993, 2018.10.
15. Sunraso, Akira Tsuchiya, Naoyuki Fukuda, Riki Toita, Kanji Tsuru, Kunio Ishikawa, Effect of micro-roughening of poly(ether ether ketone) on bone marrow derived stem cell and macrophage responses, and osseointegration, Journal of Biomaterials Science, Polymer Edition, 10.1080/09205063.2018.1461448, 1-14, 2018.08.
16. Kunio Ishikawa, Tansza Setiana Putri, Akira Tsuchiya, Keisuke Tanaka, Kanji Tsuru, Fabrication of interconnected porous β-tricalcium phosphate (β-TCP) based on a setting reaction of β-TCP granules with HNO3 followed by heat treatment, Journal of Biomedical Materials Research - Part A, 10.1002/jbm.a.36285, 106, 3, 797-804, 2018.03, これまでブロック状、顆粒状の人工骨補填材が市販・臨床応用されている。一方で、実際の骨は多孔体構造をしている海綿骨が、緻密な皮質骨よりも骨形成が早いことが知られており、人工骨補填材においても多孔体構造が骨再生を促進する可能性が指摘されていた。多孔体化の一番容易な手法は顆粒の焼結反応であるが、一般的に人工骨補填材として用いられるリン酸カルシウムは高温で不安定なため、焼結反応を用いることができない。本研究では、リン酸三カルシウム顆粒をリン酸水素カルシウムの橋架けにより多孔体化し、焼成反応、化学反応を用いて純粋なリン酸三カルシウム多孔体を創製した。.
17. Akira Tsuchiya, Jeong Hun Kang, Takeshi Mori, Yuki Naritomi, Satoshi Kushio, Takuro Niidome, Katsuro Tachibana, Yoko Takahashi, Yoichi Negishi, Yusuke Oda, Ryo Suzuki, kazuo Maruyama, Yoshiki Katayama, Efficient delivery of signal-responsive gene carriers for disease-specific gene expression via bubble liposomes and sonoporation, Colloids and Surface B - Biointerfaces, 10.1016/j.colsurfb.2017.09.021, 160, 60-64, 2017.12.
18. Akira Tsuchiya, Siti Norulhuda Hashim, Shoko Ise, Takafumi Furuhata, Kiyohiko Kawai, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya, Shinsuke Sando, BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells, ANALYTICAL SCIENCES, 32, 5, 543-547, 2016.05.
19. Siti Norulhuda Hashim, Akira Tsuchiya, Noriho Kamiya, Shinsuke Sando, A Single Fluorophore-labeled Aptamer Sensor for the Detection of Interferon Gamma, Chem. Lett., 44, 12, 1670-1672, 2015.12.
20. Hiroshi Nonaka, Qi An, Fuminori Sugihara, Tomohiro Doura, Akira Tsuchiya, Yoshichika Yoshioka, Shinsuke Sando, Phenylboronic Acid-based F-19 MRI Probe for the Detection and Imaging of Hydrogen Peroxide Utilizing Its Large Chemical-Shift Change, ANALYTICAL SCIENCES, 31, 4, 331-335, 2015.04.
21. Yuta Nakamura, Chan Woo Kim, Akira Tsuchiya, Satoshi Kushio, Takanobu Nobori, Kai Ki, Eun Kyong Lee, Guo Xi Zhao, Daiki Funamoto, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Branched polyethylenimine-based PKCα-responsive gene carriers, J. Biomater. Sci.-Polym. Ed, 24, 1858-1868, 2013.05.
22. Satoshi Kushio, Akira Tsuchiya, Yuta Nakamura, Chan Woo Kim, Guo Xi Zhao, Daiki Funamoto, Eun Kyung Lee, Kai Lee, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Cancer-specific gene carriers responding to cancer microenvironment: acidosis and hyper-activated protein kinases, Biomedical Engineering, 25, 1340005-1340016, 2013.05.
23. Hidetoshi Arima, Ayumi Yoshimatsu, Haruma Ikeda, Ayumu Ohyama, Keiichi Motoyama, Taishi Higashi, Akira Tsuchiya, Takuro Niidome, Yoshiki Katayama, Kenjiro Hattori, Tomoko Takeuchi, Folate-PEG-Appended Dendrimer Conjugate with alpha-Cyclodextrin as a Novel Cancer Cell-Selective siRNA Delivery Carrier, MOLECULAR PHARMACEUTICS, 10.1021/mp300188f, 9, 9, 2591-2604, 2012.09.
24. Akira Tsuchiya, Yuki Naritomi, Satoshi Kushio, Jeong-Hun Kang, Masaharu Murata, Makoto Hashizume, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Improvement in the colloidal stability of protein kinase-responsive polyplexes by PEG modification, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 10.1002/jbm.a.34049, 100A, 5, 1136-1141, 2012.05.
25. Akira Tsuchiya, Daisuke Asai, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Correlation between phosphorylation ratios by MALDI-TOF MS analysis and radioactivities by radioactive assay, Anal. Biochem, 2011.10.
26. Jeong-Hun Kang, Daisuke Asai, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2), PLoS ONE, 2011.07.
27. Akira Tsuchiya, Jeong-Hun Kang, Daisuke Asai, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Transgene regulation system responding to Rho associated coiled-coil kinase (ROCK) activation, JOURNAL OF CONTROLLED RELEASE, 10.1016/j.jconrel.2011.05.002, 155, 1, 40-46, 2011.10.
28. Jun Oishi, Joohee Jung, Akira Tsuchiya, Riki Toita, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Katsuyuki Tanizawa, Shun'ichi Kuroda, Yoshiki Katayama, A gene delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer, Int. J. Pharm., 396, 174-178, 2010.12.
29. Daisuke Asai, Akira Tsuchiya, Jeong-Hun Kang, Kenji Kawamura, Jun Oishi, Takeshi Mori, Takuro Niidome, Yoko Shoji, Hideki Nakashima, Yoshiki Katayama, Inflammatory cell-specific gene regulation system responding to Ikappa-B kinase beta activation, J. Gene Med, 2009.05.
30. Daisuke Asai, Jeong-Hun Kang, Riki Toita, Akira Tsuchiya, Takuro Niidome, Hideki Nakashima, Yoshiki Katayama, Regulation of Transgene Expression in Tumor Cells by Exploiting Endogenous Intracellular Signals, NANOSCALE RESEARCH LETTERS, 10.1007/s11671-008-9230-5, 4, 3, 229-233, 2009.03.
31. Jeong-Hun Kang, Masanori Kuramoto, Akira Tsuchiya, Riki Toita, Daisuke Asai, Yuko T. Sato, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Correlation between phosphorylation ratios by MALDI-TOF MS analysis and enzyme kinetics, Eur. J. Mass Spectrom., 2008.05.

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